Search

Your search keyword '"Riverol, Mario"' showing total 217 results
Start Over Author "Riverol, Mario"
217 results on '"Riverol, Mario"'

3. Awareness of Diagnosis in Persons with Early-Stage Alzheimer’s Disease: An Observational Study in Spain

Author

Villarejo-Galende, Alberto, García-Arcelay, Elena, Piñol-Ripoll, Gerard, del Olmo-Rodríguez, Antonio, Viñuela, Félix, Boada, Mercè, Franco-Macías, Emilio, de la Peña, Almudena Ibañez, Riverol, Mario, Puig-Pijoan, Albert, Abizanda-Soler, Pedro, Arroyo, Rafael, Baquero-Toledo, Miquel, Feria-Vilar, Inmaculada, Balasa, Mircea, Berbel, Ángel, Rodríguez-Rodríguez, Eloy, Vieira-Campos, Alba, García-Ribas, Guillermo, Rodrigo-Herrero, Silvia, Lleó, Albert, and Maurino, Jorge

Published
2022
Full Text
View/download PDF

5. Magnetic Resonance‐Guided Focused Ultrasound (MRgFUS)‐Thalamotomy for Essential Tremor: Lesion Location and Clinical Outcomes

Author

Arcadi, Alana, primary, Aviles‐Olmos, Iciar, additional, Gonzalez‐Quarante, Lain Hermes, additional, Gorospe, Arantza, additional, Jiménez‐Huete, Adolfo, additional, de la Corte, Marta Macías, additional, Parras, Olga, additional, Martin‐Bastida, Antonio, additional, Riverol, Mario, additional, Villino, Rafael, additional, Guridi, Jorge, additional, and Rodríguez‐Oroz, Maria C., additional

Published
2024
Full Text
View/download PDF

6. Clusters of cognitive performance predict long‐term cognitive impairment in elderly patients with subjective memory complaints and healthy controls.

Author

Jiménez‐Huete, Adolfo, Villino‐Rodríguez, Rafael, Ríos‐Rivera, Mirla M., Rognoni, Teresa, Montoya‐Murillo, Genoveva, Arrondo, Carlota, Zapata, Carolina, Rodríguez‐Oroz, María Cruz, and Riverol, Mario

Abstract

INTRODUCTION: Patients with subjective memory complaints (SMC) may include subgroups with different neuropsychological profiles and risks of cognitive impairment. METHODS: Cluster analysis was performed on two datasets (n: 630 and 734) comprising demographic and neuropsychological data from SMC and healthy controls (HC). Survival analyses were conducted on clusters. Bayesian model averaging assessed the predictive utility of clusters and other biomarkers. RESULTS: Two clusters with higher and lower than average cognitive performance were detected in SMC and HC. Assignment to the lower performance cluster increased the risk of cognitive impairment in both datasets (hazard ratios: 1.78 and 2.96; Plog‐rank: 0.04 and <0.001) and was associated with lower hippocampal volumes and higher tau/amyloid beta 42 ratios in cerebrospinal fluid. The effect of SMC was small and confounded by mood. DISCUSSION: This study provides evidence of the presence of cognitive clusters that hold biological significance and predictive value for cognitive decline in SMC and HC. Highlights: Patients with subjective memory complaints include two cognitive clusters.Assignment to the lower performance cluster increases risk of cognitive impairment.This cluster shows a pattern of biomarkers consistent with incipient Alzheimer's disease pathology.The same cognitive cluster structure is found in healthy controls.The effect of memory complaints on risk of cognitive decline is small and confounded. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

12. Medical help-seeking intentions among patients with early Alzheimer’s disease

Author

Villarejo-Galende, Alberto, primary, García-Arcelay, Elena, additional, Piñol-Ripoll, Gerard, additional, del Olmo-Rodríguez, Antonio, additional, Viñuela, Félix, additional, Boada, Mercè, additional, Franco-Macías, Emilio, additional, Ibañez de la Peña, Almudena, additional, Riverol, Mario, additional, Puig-Pijoan, Albert, additional, Abizanda-Soler, Pedro, additional, Arroyo, Rafael, additional, Baquero-Toledo, Miquel, additional, Feria-Vilar, Inmaculada, additional, Balasa, Mircea, additional, Berbel, Ángel, additional, Rodríguez-Rodríguez, Eloy, additional, Vieira-Campos, Alba, additional, Garcia-Ribas, Guillermo, additional, Rodrigo-Herrero, Silvia, additional, Lleó, Alberto, additional, and Maurino, Jorge, additional

Published
2023
Full Text
View/download PDF

18. Quality of Life and the Experience of Living with Early-Stage Alzheimer’s Disease

Author

Villarejo-Galende, Alberto, primary, García-Arcelay, Elena, additional, Piñol-Ripoll, Gerard, additional, del Olmo-Rodríguez, Antonio, additional, Viñuela, Félix, additional, Boada, Mercè, additional, Franco-Macías, Emilio, additional, Ibañez de la Peña, Almudena, additional, Riverol, Mario, additional, Puig-Pijoan, Albert, additional, Abizanda-Soler, Pedro, additional, Arroyo, Rafael, additional, Baquero-Toledo, Miquel, additional, Feria-Vilar, Inmaculada, additional, Balasa, Mircea, additional, Berbel, Ángel, additional, Rodríguez-Rodríguez, Eloy, additional, Vieira-Campos, Alba, additional, García-Ribas, Guillermo, additional, Rodrigo-Herrero, Silvia, additional, Terrancle, Ángeles, additional, Prefasi, Daniel, additional, Lleó, Alberto, additional, and Maurino, Jorge, additional

Published
2022
Full Text
View/download PDF

22. Awareness of Diagnosis in Persons with Early-Stage Alzheimer's Disease: An Observational Study in Spain

Author

Roche, Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas (España), European Commission, European Federation of Pharmaceutical Industries and Associations, Instituto de Salud Carlos III, Grifols, Fundación la Caixa, Villarejo-Galende, Alberto, García-Arcelay, Elena, Piñol-Ripoll, Gerard, Olmo-Rodríguez, Antonio del, Viñuela, Félix, Boada, Mercè, Franco-Macías, Emilio, Ibáñez de la Peña, Almudena, Riverol, Mario, Puig-Pijoan, Albert, Abizanda-Soler, Pedro, Arroyo, Rafael, Baquero, Miquel, Feria-Vilar, Inmaculada, Balasa, Mircea, Berbel, Ángel, Rodríguez-Rodríguez, Eloy, Vieira-Campos, Alba, García-Ribas, Guillermo, Rodrigo-Herrero, Silvia, Lleó, Alberto, Maurino, Jorge, Roche, Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas (España), European Commission, European Federation of Pharmaceutical Industries and Associations, Instituto de Salud Carlos III, Grifols, Fundación la Caixa, Villarejo-Galende, Alberto, García-Arcelay, Elena, Piñol-Ripoll, Gerard, Olmo-Rodríguez, Antonio del, Viñuela, Félix, Boada, Mercè, Franco-Macías, Emilio, Ibáñez de la Peña, Almudena, Riverol, Mario, Puig-Pijoan, Albert, Abizanda-Soler, Pedro, Arroyo, Rafael, Baquero, Miquel, Feria-Vilar, Inmaculada, Balasa, Mircea, Berbel, Ángel, Rodríguez-Rodríguez, Eloy, Vieira-Campos, Alba, García-Ribas, Guillermo, Rodrigo-Herrero, Silvia, Lleó, Alberto, and Maurino, Jorge

Abstract

[Introduction] Limited information is available on people’s experiences of living with Alzheimer’s disease (AD) at earlier stages. This study assessed awareness of diagnosis among people with early-stage AD and its impact on different person-centered outcome measures., [Methods] We conducted an observational, cross-sectional study in 21 memory clinics in Spain. Persons aged 50–90 years, diagnosed with prodromal or mild AD (NIA/AA criteria), a Mini Mental State Examination (MMSE) score ≥ 22, and a Clinical Dementia Rating-Global score (CDR-GS) of 0.5 or 1.0 were recruited. The Representations and Adjustment to Dementia Index (RADIX) was used to assess participants’ beliefs about their condition and its consequences., [Results] A total of 149 persons with early-stage AD were studied. Mean (SD) age was 72.3 (7.0) years and 50.3% were female. Mean duration of AD was 1.4 (1.8) years. Mean MMSE score was 24.6 (2.1) and 87.2% had a CDR-GS score of 0.5. Most participants (n = 84, 57.5%) used a descriptive term related to specific AD symptoms (e.g., memory difficulties) when asked what they called their condition. Participants aware of their diagnosis using the term AD (n = 66, 45.2%) were younger, had more depressive symptoms, and poorer life satisfaction and quality of life compared to those without awareness of their specific diagnosis. Practical and emotional consequences RADIX scores showed a significant negative correlation with Quality of Life in Alzheimer’s Disease score (rho = − 0.389 and − 0.413, respectively; p < 0.0001). Years of education was the only predictor of awareness of AD diagnosis [OR = 1.04 (95% CI 1.00–1.08); p = 0.029]., [Conclusions] Awareness of diagnosis was a common phenomenon in persons with early-stage AD negatively impacting their quality of life. Understanding illness representations in earlier stages may facilitate implementing optimized care that supports improved quality of life and well-being.

Published
2022

23. Quality of Life and the Experience of Living with Early-Stage Alzheimer's Disease

Author

Roche, Villarejo-Galende, Alberto, García-Arcelay, Elena, Piñol-Ripoll, Gerard, Olmo-Rodríguez, Antonio del, Viñuela, Félix, Boada, Mercè, Franco-Macías, Emilio, Ibáñez de la Peña, Almudena, Riverol, Mario, Puig-Pijoan, Albert, Abizanda-Soler, Pedro, Arroyo, Rafael, Baquero, Miquel, Feria-Vilar, Inmaculada, Balasa, Mircea, Berbel, Ángel, Rodríguez-Rodríguez, Eloy, Vieira-Campos, Alba, García-Ribas, Guillermo, Rodrigo-Herrero, Silvia, Terrancle, Ángeles, Prefasi, Daniel, Lleó, Alberto, Maurino, Jorge, Roche, Villarejo-Galende, Alberto, García-Arcelay, Elena, Piñol-Ripoll, Gerard, Olmo-Rodríguez, Antonio del, Viñuela, Félix, Boada, Mercè, Franco-Macías, Emilio, Ibáñez de la Peña, Almudena, Riverol, Mario, Puig-Pijoan, Albert, Abizanda-Soler, Pedro, Arroyo, Rafael, Baquero, Miquel, Feria-Vilar, Inmaculada, Balasa, Mircea, Berbel, Ángel, Rodríguez-Rodríguez, Eloy, Vieira-Campos, Alba, García-Ribas, Guillermo, Rodrigo-Herrero, Silvia, Terrancle, Ángeles, Prefasi, Daniel, Lleó, Alberto, and Maurino, Jorge

Abstract

[Background] There is a need to better understand the experience of patients living with Alzheimer's disease (AD) in the early stages., [Objective] The aim of the study was to evaluate the perception of quality of life in patients with early-stage AD., [Methods] A multicenter, non-interventional study was conducted including patients of 50–90 years of age with prodromal or mild AD, a Mini-Mental State Examination (MMSE) score ≥22, and a Clinical Dementia Rating-Global score (CDR-GS) of 0.5.–1.0. The Quality of Life in Alzheimer ’s Disease (QoL-AD) questionnaire was used to assess health-related quality of life. A battery of self-report instruments was used to evaluate different psychological and behavioral domains. Associations between the QoL-AD and other outcome measures were analyzed using Spearman’s rank correlations., [Results] A total of 149 patients were included. Mean age (SD) was 72.3 (7.0) years and mean disease duration was 1.4 (1.8) years. Mean MMSE score was 24.6 (2.1). The mean QoL-AD score was 37.9 (4.5). Eighty-three percent (n = 124) of patients had moderate-to-severe hopelessness, 22.1% (n = 33) had depressive symptoms, and 36.9% (n = 55) felt stigmatized. The quality of life showed a significant positive correlation with self-efficacy and negative correlations with depression, emotional and practical consequences, stigma, and hopelessness., [Conclusion] Stigma, depressive symptoms, and hopelessness are frequent scenarios in AD negatively impacting quality of life, even in a population with short disease duration and minimal cognitive impairment.

Published
2022

26. Person-centered Assessment in Early Alzheimer’s Disease (P1-1.Virtual)

Author

Galende, Alberto Villarejo, primary, Garcia-Arcelay, Elena, additional, Pinol-Ripoll, Gerard, additional, del Olmo-Rodriguez, Antonio, additional, Vinuela, Felix, additional, Rovira, Merce Boada, additional, Franco-Macias, Emilio, additional, Ibañez, Almudena, additional, Riverol, Mario, additional, Pijoan, Albert Puig, additional, Abizanda, Pedro, additional, Gonzalez, Rafael Arroyo, additional, Baquero, Miquel, additional, Feria, Inmaculada, additional, Balasa, Mircea, additional, Berbel, Angel, additional, Rodriguez-Rodriguez, Eloy, additional, Vieira, Alba, additional, Garcia-Ribas, Guillermo, additional, Rodrigo-Herrero, Silvia, additional, Lleo, Alberto, additional, Morales, Eduardo Aguera, additional, Catalán-Flores, Carmen, additional, and Maurino, Jorge, additional

Published
2022
Full Text
View/download PDF

30. Additional file 1 of Mixed pathologies in pancreatic β cells from subjects with neurodegenerative diseases and their interaction with prion protein

Author

Martinez-Valbuena, Ivan, Valenti-Azcarate, Rafael, Amat-Villegas, Irene, Marcilla, Irene, Marti-Andres, Gloria, Maria-Cristina Caballero, Riverol, Mario, María-Teresa Tuñon, Fraser, Paul E., and Luquin, María-Rosario

Subjects
ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, ComputingMilieux_COMPUTERSANDEDUCATION, Data_FILES, ComputerApplications_COMPUTERSINOTHERSYSTEMS
Abstract

Additional file 1. Supplementary figures and tables.

Published
2021
Full Text
View/download PDF

31. Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment:A European Alzheimer's disease consortium survey

Author

Frederiksen, Kristian S., Nielsen, Thomas R., Appollonio, Ildebrando, Andersen, Birgitte Bo, Riverol, Mario, Boada, Mercè, Ceccaldi, Mathieu, Dubois, Bruno, Engelborghs, Sebastiaan, Frölich, Lutz, Hausner, Lucrezia, Gabelle, Audrey, Gabryelewicz, Tomasz, Grimmer, Timo, Hanseeuw, Bernard, Hort, Jakub, Hugon, Jacques, Jelic, Vesna, Koivisto, Anne, Kramberger, Milica G., Lebouvier, Thibaud, Lleó, Alberto, de Mendonça, Alexandre, Nobili, Flavio, Ousset, Pierre Jean, Perneczky, Robert, Olde Rikkert, Marcel, Robinson, David, Rouaud, Olivier, Sánchez, Elisabet, Santana, Isabel, Scarmeas, Nikolaos, Sheardova, Katerina, Sloan, Stephanie, Spiru, Luiza, Stefanova, Elka, Traykov, Latchezar, Yener, Görsev, Waldemar, Gunhild, Frederiksen, Kristian S., Nielsen, Thomas R., Appollonio, Ildebrando, Andersen, Birgitte Bo, Riverol, Mario, Boada, Mercè, Ceccaldi, Mathieu, Dubois, Bruno, Engelborghs, Sebastiaan, Frölich, Lutz, Hausner, Lucrezia, Gabelle, Audrey, Gabryelewicz, Tomasz, Grimmer, Timo, Hanseeuw, Bernard, Hort, Jakub, Hugon, Jacques, Jelic, Vesna, Koivisto, Anne, Kramberger, Milica G., Lebouvier, Thibaud, Lleó, Alberto, de Mendonça, Alexandre, Nobili, Flavio, Ousset, Pierre Jean, Perneczky, Robert, Olde Rikkert, Marcel, Robinson, David, Rouaud, Olivier, Sánchez, Elisabet, Santana, Isabel, Scarmeas, Nikolaos, Sheardova, Katerina, Sloan, Stephanie, Spiru, Luiza, Stefanova, Elka, Traykov, Latchezar, Yener, Görsev, and Waldemar, Gunhild

Abstract

Objectives: Mild cognitive impairment (MCI) is associated with an increased risk of further cognitive decline, partly depending on demographics and biomarker status. The aim of the present study was to survey the clinical practices of physicians in terms of biomarker counseling, management, and follow-up in European expert centers diagnosing patients with MCI. Methods: An online email survey was distributed to physicians affiliated with European Alzheimer's disease Consortium centers (Northern Europe: 10 centers; Eastern and Central Europe: 9 centers; and Southern Europe: 15 centers) with questions on attitudes toward biomarkers and biomarker counseling in MCI and dementia. This included postbiomarker counseling and the process of diagnostic disclosure of MCI, as well as treatment and follow-up in MCI. Results: The response rate for the survey was 80.9% (34 of 42 centers) across 20 countries. A large majority of physicians had access to biomarkers and found them useful. Pre- and postbiomarker counseling varied across centers, as did practices for referral to support groups and advice on preventive strategies. Less than half reported discussing driving and advance care planning with patients with MCI. Conclusions: The variability in clinical practices across centers calls for better biomarker counseling and better training to improve communication skills. Future initiatives should address the importance of communicating preventive strategies and advance planning.

Published
2021

37. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes

Author

Thelen, Mathias, Razquin, Cristina, Hernández, Isabel, Gorostidi, Ana, Sánchez-Valle, Raquel, Ortega-Cubero, Sara, Wolfsgruber, Steffen, Drichel, Dmitriy, Fliessbach, Klaus, Duenkel, Tanja, Damian, Marinella, Heilmann, Stefanie, Slotosch, Anja, Lennarz, Martina, Seijo-Martínez, Manuel, Rene, Ramón, Kornhuber, Johannes, Peters, Oliver, Luckhaus, Christian, Jahn, Holger, Hüll, Michael, Rüther, Eckart, Wiltfang, Jens, Lorenzo, Elena, Gascon, Jordi, Lleó, Alberto, Lladó, Albert, Campdelacreu, Jaume, Moreno, Fermin, Ahmadzadehfar, Hojjat, Fortea, Juan, Indakoetxea, Begoña, Heneka, Michael T., Wetter, Axel, Pastor, Maria A., Riverol, Mario, Becker, Tim, Frölich, Lutz, Tárraga, Lluís, Boada, Mercè, Wagner, Michael, Jessen, Frank, Maier, Wolfgang, Clarimón, Jordi, López de Munain, Adolfo, Ruiz, Agustín, Pastor, Pau, and Ramirez, Alfredo

Published
2014
Full Text
View/download PDF

40. Biomarker counseling, disclosure of diagnosis and follow‐up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey

Author

Frederiksen, Kristian S., primary, Nielsen, Thomas R., additional, Appollonio, Ildebrando, additional, Andersen, Birgitte Bo, additional, Riverol, Mario, additional, Boada, Mercè, additional, Ceccaldi, Mathieu, additional, Dubois, Bruno, additional, Engelborghs, Sebastiaan, additional, Frölich, Lutz, additional, Hausner, Lucrezia, additional, Gabelle, Audrey, additional, Gabryelewicz, Tomasz, additional, Grimmer, Timo, additional, Hanseeuw, Bernard, additional, Hort, Jakub, additional, Hugon, Jacques, additional, Jelic, Vesna, additional, Koivisto, Anne, additional, Kramberger, Milica G., additional, Lebouvier, Thibaud, additional, Lleó, Alberto, additional, de Mendonça, Alexandre, additional, Nobili, Flavio, additional, Ousset, Pierre‐Jean, additional, Perneczky, Robert, additional, Olde Rikkert, Marcel, additional, Robinson, David, additional, Rouaud, Olivier, additional, Sánchez, Elisabet, additional, Santana, Isabel, additional, Scarmeas, Nikolaos, additional, Sheardova, Katerina, additional, Sloan, Stephanie, additional, Spiru, Luiza, additional, Stefanova, Elka, additional, Traykov, Latchezar, additional, Yener, Görsev, additional, and Waldemar, Gunhild, additional

Published
2020
Full Text
View/download PDF

41. Multicenter Validation of Metabolic Abnormalities Related to PSP According to the MDS‐PSP Criteria

Author

Martí‐Andrés, Gloria, primary, van Bommel, Liza, additional, Meles, Sanne K., additional, Riverol, Mario, additional, Valentí, Rafael, additional, Kogan, Rosalie V., additional, Renken, Remco J., additional, Gurvits, Vita, additional, van Laar, Teus, additional, Pagani, Marco, additional, Prieto, Elena, additional, Luquin, M. Rosario, additional, Leenders, Klaus L., additional, and Arbizu, Javier, additional

Published
2020
Full Text
View/download PDF

46. Psychosocial Adjustment to Illness Scale in family caregivers of patients with Parkinson's Disease: Spanish validation study.

Author

Ambrosio, Leire, Navarta‐Sánchez, Mª Victoria, Portillo, Mª Carmen, Martin‐Lanas, Raquel, Recio, Miriam, and Riverol, Mario

Subjects
RELIABILITY (Personality trait), CAREGIVERS, RESEARCH evaluation, PSYCHOLOGICAL adjustment testing, RESEARCH methodology evaluation, CROSS-sectional method, RESEARCH methodology, DISEASES, HEALTH surveys, PSYCHOMETRICS, MULTITRAIT multimethod techniques, PARKINSON'S disease, QUESTIONNAIRES, DESCRIPTIVE statistics, CHI-squared test
Abstract

Psychosocial adjustment to a complex and disabling long‐term condition like Parkinson´s disease is a complex, dynamic, cyclical and interactive process. Family caregivers, face multiple challenges that require a significant effort in terms of psychosocial adjustment, which must be considered by healthcare professionals in order to provide a holistic care. The patients' self‐report version of the Psychosocial Adjustment to Illness Scale (PAIS‐SR), which has been validated in Spain for use in Parkinson's disease, is designed to evaluate the psychosocial adjustment of patients. Our purpose was to validate the Spanish PAIS‐SR version for caregivers of patients with Parkinson's disease. An open, national cross‐sectional study with one point‐in‐time evaluation and retest was carried out in 450 family caregivers of patients with Parkinson's disease. Data were collected in Spain from April 2016 to September 2017. The psychometric analysis performed showed that the Spanish version of the PAIS‐SR for caregivers presents adequate indicators of reliability, internal and external validity, and is structured according to the seven‐domain model proposed by the author of the instrument. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

49. Amylin as a potential link between type 2 diabetes and alzheimer disease

Author

Martinez‐Valbuena, Ivan, primary, Valenti‐Azcarate, Rafael, additional, Amat‐Villegas, Irene, additional, Riverol, Mario, additional, Marcilla, Irene, additional, Andrea, Carlos E., additional, Sánchez‐Arias, Juan Antonio, additional, Mar Carmona‐Abellan, Maria, additional, Marti, Gloria, additional, Erro, Maria‐Elena, additional, Martínez‐Vila, Eduardo, additional, Tuñon, Maria‐Teresa, additional, and Luquin, Maria‐Rosario, additional

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results