78 results on '"Riveros, S."'
Search Results
2. Portomesenteric Jump Graft for Deceased Donor Liver Transplantation. Single Center Experience of 15 Cases in Latin America
- Author
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Briceño, E., primary, Riveros, S., additional, Artigas, G., additional, Irarrazaval, M.J., additional, Ochoa, G., additional, Rebolledo, P., additional, Achurra, P., additional, Viñuela, E., additional, Jarufe, N., additional, and Dib, M., additional
- Published
- 2022
- Full Text
- View/download PDF
3. Management of Biliary Complications after Living Donor Liver Transplantation. The Initial Experience of a Single Center
- Author
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Riveros, S., primary, Irarrázaval, M.J., additional, Ochoa, G., additional, Artigas, G., additional, Arab, J.P., additional, Wolf, R., additional, Barrera, F., additional, Benitez, C., additional, Achurra, P., additional, Martinez, J., additional, Viñuela, E., additional, Jarufe, N., additional, Espino, A., additional, Briceño, E., additional, and Dib, M., additional
- Published
- 2022
- Full Text
- View/download PDF
4. Contralateral Liver Tumor Behavior after Portal Embolization: Are Two-Stage Hepatectomies Always Justified?
- Author
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Riveros, S., primary, Irarrazabal, M.J., additional, Peñailillo, A., additional, Hevia, J., additional, Achurra, P., additional, Briceño, E., additional, Viñuela, E., additional, Jarufe, N., additional, Martinez, J., additional, Meneses, L., additional, and Dib, M., additional
- Published
- 2022
- Full Text
- View/download PDF
5. Double prevalence of appendicular peritonitis during COVID times
- Author
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Riveros, S, primary, Artigas, G, additional, Inzunza, M, additional, Rebolledo, R, additional, Brañes, A, additional, Crovari, F, additional, and Achurra, P, additional
- Published
- 2021
- Full Text
- View/download PDF
6. Management of biliary complications after adult-to-adult living donor liver transplantation. Initial experience in a latin american center
- Author
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Riveros, S., primary, Irarrázaval, M.J., additional, Ochoa, G., additional, Artigas, G., additional, Briceño, E., additional, Arab, J.P., additional, Wolff, R., additional, Barrera, F., additional, Benítez, C., additional, Achurra, P., additional, Viñuela, E., additional, Meneses, L., additional, Espino, A., additional, Martínez, J., additional, and Dib, M., additional
- Published
- 2021
- Full Text
- View/download PDF
7. Contralateral liver tumor behavior after portal embolization: are two-stage hepatectomies always justified?
- Author
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Riveros, S., primary, Irarrázaval, M.J., additional, Peñailillo, A., additional, Hevia, J., additional, Achurra, P., additional, Briceño, E., additional, Viñuela, E., additional, Jarufe, N., additional, Martinez, J., additional, Meneses, L., additional, and Dib, M., additional
- Published
- 2021
- Full Text
- View/download PDF
8. Adult-pediatric living donor liver transplant in recipients >20kg with full left lobe grafts.
- Author
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Ortiz, C., Riveros, S., Meira, J.D., Pattillo, J.C., Soriano, H., Gana, J.C., Viñuela, E., Jarufe, N., Martinez, J., Briceño, E., and Dib, M.
- Published
- 2024
- Full Text
- View/download PDF
9. Impact of liver transplantation on the use of healthcare resources on the waiting list: analysis of transplantation with living donors, deceased donors and non-transplanted candidates.
- Author
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Riveros, S., Garcia, D., Irarrazabal, M.J., Achurra, P., Briceño, E., Viñuela, E., Rebolledo, P., Jarufe, N., Martinez, J., and Dib, M.
- Published
- 2024
- Full Text
- View/download PDF
10. Measurement of NADH in perfusate of liver during HOPE.
- Author
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Rivas, E., Riveros, S., Benitez, J., Galaz, V., Soto, D., and Rebolledo, R.
- Published
- 2024
- Full Text
- View/download PDF
11. Te invito a un café
- Author
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Juliana Riveros S. and Juliana Riveros S.
- Abstract
¿Tienes idea de lo complicado que es ser un chico guapo y que la mujer que deseas no te preste atención? Tras sufrir un problema amoroso con su exesposa, Nathaniel Brown decide abandonar Madrid y empezar una nueva vida en Londres, trabajando como corrector de estilo para una editorial. Pasados dos años, en los cuales ha tenido que lidiar con los escándalos que le arma su exmujer, conoce a Anne Brooks, una bailarina de ballet llena de fuerza y vitalidad, pero con una condición particular que resulta ser un impedimento para que los métodos de conquista de Nathaniel funcionen. Con el pasar del tiempo y los problemas que le ha traído la pequeña «niñata», como la llama Nathaniel, Anne empieza a sentir una pequeña atracción hacia él. Sin embargo, no quiere ponérselo fácil; ella tiene una idea muy clara de lo que buscan los hombres y sabe que debe mantener la guardia arriba. Aunque la relación entre los dos empieza a mejorar, surge un nuevo problema: alguien no quiere verlos juntos. Varios atentados en su contra empiezan a llegar, afectando física y emocionalmente a todo aquel que tenga relación con ellos. ¿Cómo enamoras a una mujer que no desea tener nada contigo?, ¿cuántas veces tienes que equivocarte en el amor para aprender la lección?, ¿cómo proteges a la persona que quieres de un peligro que no logras comprender? Nathaniel está dispuesto a narrar su historia, contando los dolores de cabeza que la testaruda Anne Brooks ha traído a su vida y cómo lidiar con ellos ha sido lo mejor que le ha pasado en mucho tiempo.
- Published
- 2021
12. Un modelo estructural para medir la efectividad de los servicios hospitalarios: aplicación en hospitales públicos del sur de Chile
- Author
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Esperanza García-Uceda, Jorge Riveros S, and Carmen Berné M
- Subjects
Service (business) ,business.industry ,media_common.quotation_subject ,User satisfaction ,Management audit ,Hospitals, public ,Patient satisfaction ,General Medicine ,Health Services accessibility ,Structural equation modeling ,Test (assessment) ,Public health care ,Nursing ,Order (business) ,Medicine ,Quality (business) ,business ,media_common - Abstract
Background: One of the main determinants of quality in the public health care services is the perceived user satisfaction. Aim: To analyze the relationship between supply (User Orientation of Management) (UO), demand (User Satisfaction with service components) (US) and subjective indicators of effectiveness, such as Perceived Global Quality (PGQ) and Global Satisfaction (GS) among hospital service users. Material and Methods: A survey was applied to users of hospital services, asking about management and quality of hospital services and satisfaction with the service provided. Data was analyzed with exploratory and confirmatory factorial analyses. Structural Equation Models were used to test the hypotheses implied in the theoretical model of effectiveness. Results: The cause-effect relationship between UO and US was confirmed. There was also a direct relationship between PGQ and GS. Conclusions: Efficient nursing and administrative personnel are of highest importance to improve user satisfaction. The hospital management must pay extreme attention to this kind of staff in order to be effective from the point of view of their patients.
- Published
- 2012
13. Un modelo estructural para medir la efectividad de los servicios hospitalarios: aplicación en hospitales públicos del sur de Chile
- Author
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Riveros S, Jorge, Berné M, Carmen, and García-Uceda, Esperanza
- Subjects
Management audit ,Hospitals, public ,Patient satisfaction ,Health Services accessibility - Abstract
Background: One of the main determinants of quality in the public health care services is the perceived user satisfaction. Aim: To analyze the relationship between supply (User Orientation of Management) (UO), demand (User Satisfaction with service components) (US) and subjective indicators of effectiveness, such as Perceived Global Quality (PGQ) and Global Satisfaction (GS) among hospital service users. Material and Methods: A survey was applied to users of hospital services, asking about management and quality of hospital services and satisfaction with the service provided. Data was analyzed with exploratory and confirmatory factorial analyses. Structural Equation Models were used to test the hypotheses implied in the theoretical model of effectiveness. Results: The cause-effect relationship between UO and US was confirmed. There was also a direct relationship between PGQ and GS. Conclusions: Efficient nursing and administrative personnel are of highest importance to improve user satisfaction. The hospital management must pay extreme attention to this kind of staff in order to be effective from the point of view of their patients.
- Published
- 2012
14. [A structural model to measure effectiveness of hospital services]
- Author
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Jorge, Riveros S, Carmen, Berné M, and Esperanza, García-Uceda
- Subjects
Male ,Attitude of Health Personnel ,Hospitals, Public ,Patient Satisfaction ,Surveys and Questionnaires ,Humans ,Female ,Chile ,Models, Theoretical ,Health Services Accessibility ,Quality Indicators, Health Care ,Quality of Health Care - Abstract
One of the main determinants of quality in the public health care services is the perceived user satisfaction.To analyze the relationship between supply (User Orientation of Management) (UO), demand (User Satisfaction with service components) (US) and subjective indicators of effectiveness, such as Perceived Global Quality (PGQ) and Global Satisfaction (GS) among hospital service users.A survey was applied to users of hospital services, asking about management and quality of hospital services and satisfaction with the service provided. Data was analyzed with exploratory and confirmatory factorial analyses. Structural Equation Models were used to test the hypotheses implied in the theoretical model of effectiveness.The cause-effect relationship between UO and US was confirmed. There was also a direct relationship between PGQ and GS.Efficient nursing and administrative personnel are of highest importance to improve user satisfaction. The hospital management must pay extreme attention to this kind of staff in order to be effective from the point of view of their patients.
- Published
- 2011
15. Tratamiento de oesteogénesis imperfecta en un tigre (Panthera tigris)
- Author
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Antonio Horvath S., Luis Francesetti F., and Víctor Riveros S.
- Subjects
Economics and Econometrics ,Materials Chemistry ,Media Technology ,Forestry - Published
- 2010
16. Gestión y satisfacción en servicios de salud de Chile: Contraste entre las percepciones de los funcionarios y los usuarios
- Author
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RIVEROS S, JORGE, BERNÉ M, CARMEN, and MÚGICA G, JOSÉ M
- Subjects
patient care management ,Marketing of health services ,Patients - Abstract
Background: Clients and providers of health care can have contrasting perceptions about the quality of service. Provider perceptions are mostly devoted to design and delivery of services while those of clients are focused in the attention received. Aim: To assess perceptions of health care providers and clients about client management and satisfaction with services provided. Material and Methods: Two public hospitals were surveyed. A qualitative analysis was performed first, reviewing reports and patient data bases and through informal meetings with providers and clients. In a second phase, an enquiry with Likert type questions was devised and answered by a total of 377 providers and 400 clients from both hospitals. Results: The median perception of clients about the quality of service was better than that of providers in both hospitals. The communication of hospitals with clients to offer timely information received a poor evaluation both from providers and clients. However the concern of hospitals about health care of the community was considered adequate. The degree of satisfaction with concrete issues such as information panels and physical infrastructure received similar evaluation both by providers and clients. Conclusions: This analysis can be useful for management decision making, identifying strengths and weaknesses of health care provided by these two public hospitals. This type of assessment can be replicated in other public and private health care facilities.
- Published
- 2010
17. Gestión y satisfacción en servicios de salud de Chile: Contraste entre las percepciones de los funcionarios y los usuarios
- Author
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Jorge Riveros S, Josém M. Múgica G, and Carmen Berné M
- Subjects
Gerontology ,patient care management ,Physical infrastructure ,Patients ,business.industry ,Quality of service ,media_common.quotation_subject ,General Medicine ,Likert scale ,Provider perceptions ,Qualitative analysis ,Marketing of health services ,Nursing ,Perception ,Health care ,Medicine ,business ,Strengths and weaknesses ,media_common - Abstract
Background: Clients and providers of health care can have contrasting perceptions about the quality of service. Provider perceptions are mostly devoted to design and delivery of services while those of clients are focused in the attention received. Aim: To assess perceptions of health care providers and clients about client management and satisfaction with services provided. Material and Methods: Two public hospitals were surveyed. A qualitative analysis was performed first, reviewing reports and patient data bases and through informal meetings with providers and clients. In a second phase, an enquiry with Likert type questions was devised and answered by a total of 377 providers and 400 clients from both hospitals. Results: The median perception of clients about the quality of service was better than that of providers in both hospitals. The communication of hospitals with clients to offer timely information received a poor evaluation both from providers and clients. However the concern of hospitals about health care of the community was considered adequate. The degree of satisfaction with concrete issues such as information panels and physical infrastructure received similar evaluation both by providers and clients. Conclusions: This analysis can be useful for management decision making, identifying strengths and weaknesses of health care provided by these two public hospitals. This type of assessment can be replicated in other public and private health care facilities.
- Published
- 2010
18. [An enquiry on client opinions about quality of care in a public hospital]
- Author
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Jorge, Riveros S and Carmen, Berné M
- Subjects
Adult ,Male ,Adolescent ,Hospitals, Public ,Consumer Behavior ,Middle Aged ,Hospitalization ,Patient Satisfaction ,Ambulatory Care ,Humans ,Regression Analysis ,Female ,Chile ,Factor Analysis, Statistical ,Aged ,Quality of Health Care - Abstract
The level of satisfaction of patients with the services provided by public hospitals is becoming an important issue for health authorities.To analyze an enquiry applied to patients, about the level of satisfaction with the service provided by a public regional hospital in Chile.An enquiry was applied to 150 ambulatory (76% women) and 50 hospitalized patients (56% women). It included 28 questions about management aspects of health care and 20 questions about client satisfaction. Data was analyzed using factorial analysis and multiple regressions.The manners of hospital personnel were the factor with the highest impact on the perception of patients about global quality of services. Attention timing was the most influential aspect on global satisfaction.There results confirm those from abroad and can orient an adequate management of public hospital.
- Published
- 2007
19. Análisis de la opinión de usuarios sobre calidad percibida y satisfacción con hospitales públicos: Estudio de caso desde la perspectiva de la aplicación del marketing
- Author
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Riveros S, Jorge and Berné M, Carmen
- Subjects
Patient care management ,Quality of health care ,Hospitals, public - Abstract
Background: The level of satisfaction of patients with the services provided by public hospitals is becoming an important issue for health authorities. Aim: To analyze an enquiry applied to patients, about the level of satisfaction with the service provided by a public regional hospital in Chile. Material and methods: An enquiry was applied to 150 ambulatory (76% women) and 50 hospitalized patients (56% women). It included 28 questions about management aspects of health care and 20 questions about client satisfaction. Data was analyzed using factorial analysis and multiple regressions. Results: The manners of hospital personnel were the factor with the highest impact on the perception of patients about global quality of services. Attention timing was the most influential aspect on global satisfaction. Conclusions: There results confirm those from abroad and can orient an adequate management of public hospital
- Published
- 2007
20. Análisis de la opinión de usuarios sobre calidad percibida y satisfacción con hospitales públicos: Estudio de caso desde la perspectiva de la aplicación del marketing
- Author
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Carmen Berné M and Jorge Riveros S
- Subjects
Gerontology ,business.industry ,MEDLINE ,Hospitals, public ,General Medicine ,Consumer satisfaction ,Patient care management ,Patient satisfaction ,Ambulatory care ,Nursing ,Public hospital ,Quality of health care ,Medicine ,Quality of care ,business - Abstract
Background: The level of satisfaction of patients with the services provided by public hospitals is becoming an important issue for health authorities. Aim: To analyze an enquiry applied to patients, about the level of satisfaction with the service provided by a public regional hospital in Chile. Material and methods: An enquiry was applied to 150 ambulatory (76% women) and 50 hospitalized patients (56% women). It included 28 questions about management aspects of health care and 20 questions about client satisfaction. Data was analyzed using factorial analysis and multiple regressions. Results: The manners of hospital personnel were the factor with the highest impact on the perception of patients about global quality of services. Attention timing was the most influential aspect on global satisfaction. Conclusions: There results confirm those from abroad and can orient an adequate management of public hospital
- Published
- 2007
21. [Mediastinal hydatid cyst. Case report and review]
- Author
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Carlos, Alvarez Z, Pedro, Riveros S, Rubén, Miranda T, and Oriana, Yarur V
- Subjects
Adult ,Treatment Outcome ,Mediastinal Cyst ,Echinococcosis ,Humans ,Female ,Follow-Up Studies - Abstract
Hydatid disease is caused by the larval stages of a cestodes belonging to the genus Echinococcus. In humans, hydatid larva and cysts are located90% in the liver and/or lungs. Primary mediastinal location, with absence of documented lung infection, is extremely rare and has not been previously reported in Chile. We report the first case of a primary mediastinal hydatid cyst in Chile and review the literature. A 38 year old woman was admitted because of a painful right supraclavicular mass, dyspnea on exertion and logical dysphagia. Presurgical evaluation evidenced a mediastinal tumor extending to the cervical region that was successfully removed. The diagnosis of mediastinal hydatid cyst was confirmed macroscopically and by biopsy.
- Published
- 2007
22. Quiste hidatídico mediastínico: Reporte de un caso y revisión de la literatura
- Author
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Álvarez Z, Carlos, Riveros S, Pedro, Miranda T, Rubén, and Yarur V, Oriana
- Subjects
Hydatid cyst ,mediastinal tumor ,mediastinal cyst ,quiste de mediastino ,Quiste hidatídico ,tumor de mediastino - Abstract
La hidatidosis es una parasitosis producida por la larva o quiste del cestodes del género Echinococcus. Una vez que el parásito infecta al hombre se ubica, en más de 90% de los casos, en hígado o pulmón. La localización mediastínica sin afección pleuropulmonar previa es extremadamente infrecuente. En Chile no hay reporte de casos con tal ubicación. Se presenta el primer caso en Chile de un quiste hidatídico (QH) mediastínico: el caso de una mujer de 38 años que consultó por aumento de volumen doloroso supraclavicular derecho, asociado a disnea de esfuerzo y disfagia lógica, cuyo estudio preoperatorio mostró un tumor de mediastino con extensión cervical de aspecto nodal y de naturaleza incierta. Se operó con éxito en nuestro hospital, comprobándose durante la operación y por la biopsia, el diagnóstico de QH mediastínico. Adjuntamos las imágenes más relevantes y las fotografías de la operación y la pieza quirúrgica, como también una revisión de la literatura médica Hydatid disease is caused by the larval stages of a cestodes belonging to the genus Echinococcus. In humans, hydatid larva and cysts are located > 90% in the liver and/or lungs. Primary mediastinal location, with absence of documented lung infection, is extremely rare and has not been previously reported in Chile. We report the first case of a primary mediastinal hydatid cyst in Chile and review the literature. A 38 year old woman was admitted because of a painful right supraclavicular mass, dyspnea on exertion and logical dysphagia. Presurgical evaluation evidenced a mediastinal tumor extending to the cervical region that was successfully removed. The diagnosis of mediastinal hidatyd cyst was confirmed macroscopically and by biopsy
- Published
- 2007
23. Quiste hidatídico mediastínico: Reporte de un caso y revisión de la literatura
- Author
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Carlos Alvarez Z, Oriana Yarur V, Rubén Miranda T, and Pedro Riveros S
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Lung infection ,Treatment outcome ,Public Health, Environmental and Occupational Health ,Follow up studies ,Mediastinal tumor ,Hydatid cyst ,quiste de mediastino ,Quiste hidatídico ,medicine.disease ,Dysphagia ,Infectious Diseases ,parasitic diseases ,Biopsy ,medicine ,Radiology ,Genus Echinococcus ,medicine.symptom ,business ,tumor de mediastino - Abstract
La hidatidosis es una parasitosis producida por la larva o quiste del cestodes del género Echinococcus. Una vez que el parásito infecta al hombre se ubica, en más de 90% de los casos, en hígado o pulmón. La localización mediastínica sin afección pleuropulmonar previa es extremadamente infrecuente. En Chile no hay reporte de casos con tal ubicación. Se presenta el primer caso en Chile de un quiste hidatídico (QH) mediastínico: el caso de una mujer de 38 años que consultó por aumento de volumen doloroso supraclavicular derecho, asociado a disnea de esfuerzo y disfagia lógica, cuyo estudio preoperatorio mostró un tumor de mediastino con extensión cervical de aspecto nodal y de naturaleza incierta. Se operó con éxito en nuestro hospital, comprobándose durante la operación y por la biopsia, el diagnóstico de QH mediastínico. Adjuntamos las imágenes más relevantes y las fotografías de la operación y la pieza quirúrgica, como también una revisión de la literatura médica
- Published
- 2007
24. [Application of marketing strategies for the management of public hospitals from the viewpoint of the staff members]
- Author
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Jorge, Riveros S and Carmen, Berné M
- Subjects
Male ,Marketing of Health Services ,Personnel, Hospital ,Analysis of Variance ,Attitude of Health Personnel ,Hospitals, Public ,Surveys and Questionnaires ,Humans ,Regression Analysis ,Female ,Planning Techniques ,Chile ,Organizational Culture - Abstract
The implementation of the marketing strategies in public hospitals provides management advantages and improves the relationship between customers and staff.To analyze the application of marketing strategies in a public hospital, from the perspective of the staff.A structured survey that asked about perceptions in 50 items about communication between personnel and customers/users, customer satisfaction, participation in the development of new policies and incentives for efficiency was applied to a stratified sample of the staff. Factorial and regression analyses were performed to define the impact of marketing strategies on the degree of preoccupation and orientation of the organization towards the satisfaction of customer needs.The survey was applied to 74 males and 122 females. The survey showed that the orientation of the hospital towards the satisfaction of its beneficiaries basically depends on the generation of an organizational culture oriented towards them and the implementation of adequate policies in staff management and quality of service. These basic aspects can be accompanied with practices associated to the new marketing approaches such as a market orientation, customer orientation and relational marketing. All these factors presented positive and significant relations.New marketing strategies should be applied, to achieve an efficient and customer oriented hospital management.
- Published
- 2006
25. La aplicación del marketing en hospitales públicos desde la perspectiva de los funcionarios: El caso de un hospital del sur de Chile
- Author
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Carmen Berné M and Jorge Riveros S
- Subjects
Delivery of healthcare ,Marketing of Health Services ,Staff management ,Organizational culture ,Hospitals, public ,General Medicine ,Stratified sampling ,Incentive ,Customer orientation ,Public hospital ,Market orientation ,Customer satisfaction ,Business ,Marketing - Abstract
Background: The implementation of the marketing strategies in public hospitals provides management advantages and improves the relationship between customers and staff. Aim: To analyze the application of marketing strategies in a public hospital, from the perspective of the staff. Material and methods: A structured survey that asked about perceptions in 50 items about communication between personnel and customers/users, customer satisfaction, participation in the development of new policies and incentives for efficiency was applied to a stratified sample of the staff. Factorial and regression analyses were performed to define the impact of marketing strategies on the degree of preoccupation and orientation of the organization towards the satisfaction of customer needs. Results: The survey was applied to 74 males and 122 females. The survey showed that the orientation of the hospital towards the satisfaction of its beneficiaries basically depends on the generation of an organizational culture oriented towards them and the implementation of adequate policies in staff management and quality of service. These basic aspects can be accompanied with practices associated to the new marketing approaches such as a market orientation, customer orientation and relational marketing. All these factors presented positive and significant relations. Conclusions: New marketing strategies should be applied, to achieve an efficient and customer oriented hospital management
- Published
- 2006
26. La aplicación del marketing en hospitales públicos desde la perspectiva de los funcionarios: El caso de un hospital del sur de Chile
- Author
-
Riveros S, Jorge and Berné M, Carmen
- Subjects
Delivery of healthcare ,Marketing of Health Services ,Hospitals, public - Abstract
Background: The implementation of the marketing strategies in public hospitals provides management advantages and improves the relationship between customers and staff. Aim: To analyze the application of marketing strategies in a public hospital, from the perspective of the staff. Material and methods: A structured survey that asked about perceptions in 50 items about communication between personnel and customers/users, customer satisfaction, participation in the development of new policies and incentives for efficiency was applied to a stratified sample of the staff. Factorial and regression analyses were performed to define the impact of marketing strategies on the degree of preoccupation and orientation of the organization towards the satisfaction of customer needs. Results: The survey was applied to 74 males and 122 females. The survey showed that the orientation of the hospital towards the satisfaction of its beneficiaries basically depends on the generation of an organizational culture oriented towards them and the implementation of adequate policies in staff management and quality of service. These basic aspects can be accompanied with practices associated to the new marketing approaches such as a market orientation, customer orientation and relational marketing. All these factors presented positive and significant relations. Conclusions: New marketing strategies should be applied, to achieve an efficient and customer oriented hospital management
- Published
- 2006
27. GENOTIPO E3/3 DE APO E Y SU RELACIÓN CON LA RESPUESTA DE LOS LIPIDOS SÉRICOS AL COLESTEROL DIETARIO
- Author
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Jaime Rozowski N, Antonio Arteaga Ll, Ingrid Flores C, María Soledad Reyes S, Ana M Acosta B, Claudia Riveros S, and Oscar Castillo
- Subjects
Nutrition and Dietetics ,consumo de huevo ,genotipo Apo E ,dietary colesterol ,Apo E ,colesterol dietario ,egg consumption ,Apo B ,Food Science - Abstract
Introducción: Se ha descrito que el colesterol dietario produce modestos cambios en los niveles de colesterol sérico. Diversos estudios han mostrado que existe una marcada heterogeneidad en la respuesta individual frente a una dieta baja en colesterol. El polimorfismo de la apo E y sus diferentes isoformas descritas, ha sido reconocido como un factor involucrado en la variación de la respuesta y también como marcador de riesgo cardiovascular en la población. Los estudios que evalúan la respuesta dietaria en relación al gen de la apo E no han sido realizados en la población chilena. Objetivo: Evaluar la respuesta de los lípidos séricos en individuos con genotipo E3/3, frente a una intervención con colesterol dietario en la forma de un huevo sobre su dieta normal. Materiales y Métodos: Se realizó un estudio de diseño prospectivo, randomizado y crossover en 36 hombres provenientes de una institución bancaria de 25 a 55 años de edad. Se determinó colesterol plasmático total, LDL-col, HDL-col, TG, apo B y polimorfismo de apo E. Resultados: Las isoformas de apo E encontradas fueron un 79% de E3/3 y un 16% de E4/3. Los individuos E3/3 modificaron las concentraciones de colesterol total en un 0.1% luego de la adición de un huevo a la dieta por 4 semanas (209,6 ± 5,1 v/s 209,8 ± 5,6 mg/dl respectivamente, IC [- 5,0; 6,8] ). Individuos E4/3 modificaron en un 0,8% la concentración de colesterol total bajo las mismas condiciones experimentales (200,3 ± 9,4 v/s 201,8 ± 6,0 mg/dL, IC [-10,0; 13,0] ). La concentración de Apo B sérico tuvo una variación porcentual de + 5,5% para individuos E3/3 y - 2,1% para individuos E4/3, sin diferencias significativas intra y entre grupos. Conclusión: Individuos con genotipo E3/3 de apo E no modificaron significativamente sus concentraciones de colesterol total luego de la intervención con colesterol dietario, así como también los individuos E4/3 analizados. Nuestros resultados refuerzan la noción que la mayoría de la población es capaz de compensar a un aumento moderado de colesterol. Estos resultados tienen implicancia en las recomendaciones dietarias a la población Introduction: It has been described in the literature that dietary cholesterol produces only slight changes in serum cholesterol in healthy individuals. Nevertheless, several studies have shown a marked heterogeneity in the response to a variation of cholesterol in the diet. One of the factors involved in this response is the Apo E genotype, also singled as a risk factor for cardiovascular disease. There are no studies in Chile that evaluate the response to dietary cholesterol in individuals and its relationship to the Apo E genotype. Objective: To evaluate the response to a cholesterol load in individuals and relate it to their Apo E genotype. Materials and methods: A prospective randomized and cross-over study was carried out in 36 male volunteers either normolipemics or isolated hypercholesterolemic aged 25-55 years old, who were given one egg/day for 4 weeks in addition to their normal diet. Total, LDL, and HDL cholesterol were measured before and after the intervention, as well as Apo B concentration and Apo E genotype. Results: Apo E genotype was 79% E3/3 and 16% E 4/3 in this population. The addition of one egg to their normal diet did not change significantly any of the variables studied. Conclusions: Normocholesterolemic or hypercholesterolemic individuals did not respond to a load of cholesterol given in the form of one egg/day. The implications for population recommendations are discussed
- Published
- 2003
28. LA ECONOMÍA DE LOS DESASTRES NATURALES EN CHILE: EVALUACIÓN DE CAMBIOS EN SERIES ECONÓMICAS.
- Author
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Fabres A., César A., Riveros S., Gabriel E., Ainzúa Auerbach, Sebastián, and Valenzuela S., Luis A.
- Abstract
This paper aims to verify and analyze, using dummies variables, if the series of GDP, CPI and unemployment rate from Chile experience statistically significant changes in both, the short and the long term, upon the occurrence of natural disasters. To perform an answer three specific events has been assessed within the period 1990-2014, which are: a) The drought of 1994-1997 between the regions of Coquimbo and Maule; b) the flood between Copiapó and Los Angeles since April to August 1997; c) the February earthquake of 2010 from the region of Valparaíso to the region of Araucanía. According to the results it is concluded that, when analyzing and dealing with the effects generated by natural disasters in Chile, they must be under the premise that the disaster will generate significant changes in the economy, especially in the long term. [ABSTRACT FROM AUTHOR]
- Published
- 2016
29. Un modelo estructural para medir la efectividad de los servicios hospitalarios: aplicación en hospitales públicos del sur de Chile
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Riveros S, Jorge, primary, Berné M, Carmen, additional, and García-Uceda, Esperanza, additional
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- 2012
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30. Tratamiento de oesteogénesis imperfecta en un tigre (Panthera tigris)
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Horvath S., Antonio, primary, Francesetti F., Luis, additional, and Riveros S., Víctor, additional
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- 2010
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31. Gestión y satisfacción en servicios de salud de Chile: Contraste entre las percepciones de los funcionarios y los usuarios
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RIVEROS S, JORGE, primary, BERNÉ M, CARMEN, additional, and MÚGICA G, JOSÉ M, additional
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- 2010
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32. Análisis de la opinión de usuarios sobre calidad percibida y satisfacción con hospitales públicos: Estudio de caso desde la perspectiva de la aplicación del marketing
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Riveros S, Jorge, primary and Berné M, Carmen, additional
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- 2007
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33. Quiste hidatídico mediastínico: Reporte de un caso y revisión de la literatura
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Álvarez Z, Carlos, primary, Riveros S, Pedro, additional, Miranda T, Rubén, additional, and Yarur V, Oriana, additional
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- 2007
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34. La aplicación del marketing en hospitales públicos desde la perspectiva de los funcionarios: El caso de un hospital del sur de Chile
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Riveros S, Jorge, primary and Berné M, Carmen, additional
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- 2006
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35. GENOTIPO E3/3 DE APO E Y SU RELACIÓN CON LA RESPUESTA DE LOS LIPIDOS SÉRICOS AL COLESTEROL DIETARIO
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Reyes S, María Soledad, primary, Flores C, Ingrid, additional, Riveros S, Claudia, additional, Castillo V, Oscar, additional, Arteaga Ll, Antonio, additional, Acosta B, Ana María, additional, and Rozowski N, Jaime, additional
- Published
- 2003
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36. Flavin mononucleotide as a biomarker of viability in liver perfusion HOPE (Hypothermic Oxygenated Perfusion).
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Benitez, J., Rivas, E., Galaz, V., Riveros, S., Alvarez, T., Ruiz, J., Bastidas, J., Zamorano, M., Grandon, C., Contreras, M., Matulic, M., Mendoza, N., Morales, I., Fuentes, D., Norero, B., Dominguez, A., Martinez, E., Sanhueza, M., and Rebollado, R.
- Published
- 2024
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37. Explicación del Riesgo de Tasa de Interés del Libro Bancario Bajo la Perspectiva de Ganancias: Análisis de los Establecimientos de Crédito Colombianos entre los Años 2011 y 2020
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Garcia Gelvez, David Esteban, Ruiz Molina, Geraldinne Guadalupe, Riveros S, Egberto A, Pineda Ríos, Wilmer Darío, and Universidad Santo Tomás
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Estadísticas Aplicada ,Riesgo de tasa de interés ,margen financiero neto ,modelos panel ,Finanza ,credit institutions ,net financial margin ,panel models ,Interés ,establecimientos de crédito ,Interest rate risk ,Crédito ,Banco - Abstract
El riesgo de tasa de interés del libro bancario (IRRBB) se ha convertido en un factor de gestión preponderante para los establecimientos de crédito. Su medición en escenarios de estrés puede anticipar coyunturas complejas en materia de liquidez y rentabilidad que, si son previstas a tiempo, incentivan a las entidades a tomar decisiones sobre la estructura de su balance para salvaguardar su capital y margen de intermediación. Este trabajo pretende proponer un modelo estadístico que por medio del Margen Financiero Neto (NIM) pueda aproximar la exposición al IRRBB para los establecimientos de crédito colombianos. Además, se propondrán variables sectoriales y de control macroeconómico que coadyuven a una mejor interpretación de este riesgo en el contexto nacional. Los datos serán recolectados directamente de la Superintendencia Financiera de Colombia, con periodicidad mensual y en un periodo de estudio de 10 años, desde el año 2011 hasta el año 2020. Finalmente, se espera hacer una contribución metodológica al sector financiero colombiano y a la literatura latinoamericana en materia de medición y monitoreo de IRRBB, cuya literatura resulta ser escasa para esta parte de la región. Bank book interest rate risk (IRRBB) has become a preponderant management factor for credit institutions. Its measurement in stress scenarios can anticipate complex situations in terms of liquidity and profitability that, if foreseen on time, encourage entities to make decisions about the structure of their balance sheet to safeguard their capital and intermediation margin.This paper aims to propose a statistical model that through the Net Financial Margin (NIM) that can approximate the exposure to IRRBB for Colombian credit institutions. In addition, sectoral and macroeconomic control variables will be proposed that contribute to a better interpretation of this risk in the national context.The data will be collected directly from the Financial Superintendence of Colombia, monthly and over a 10-year study period, from 2011 to 2020. Finally, we hope to make a methodological contribution to the Colombian financial sector and to Latin American literature on measurement matter and monitoring of IRRBB, whose literature is scarce for this part of the region. Magister en Estadística Aplicada Maestría
- Published
- 2023
38. Seizure emergency code strategy: Improving treatment times and hospital outcomes for patients with urgent epileptic seizures.
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Espinosa-Jovel C, Riveros S, Valencia-Enciso N, Velásquez A, Vergara-Palma J, and Sobrino-Mejía F
- Abstract
Objective: Timely treatment is one of the most relevant prognostic factors in patients with urgent epileptic seizures. Despite the available evidence, treatment times remain suboptimal. The aim of this study was to demonstrate the impact of the "seizure code" in an emergency department, focusing on both treatment times and hospital outcomes of patients with urgent epileptic seizures., Methods: An ambispective cohort study was conducted in the emergency department of a public hospital in Bogotá, Colombia. Treatment times and hospital outcomes were evaluated both before and after the implementation of the seizure code., Results: A total of 336 patients were included (94 in the pre-seizure code period and 242 in the post-seizure code period). Both cohorts were comparable in terms of clinical and demographic baseline characteristics. After the implementation of the seizure code, in-hospital treatment times improved among patients with status epilepticus and seizure cluster. For the group of patients with status epilepticus, the time from arrival to the first benzodiazepine decreased from a median of 100.5 min (IQR: 43-152.5) to a median of 20 min (IQR: 10-45) (p = .0063), and the time from arrival to the first non-benzodiazepine antiseizure medication decreased from a median of 155 min (IQR: 49-194) to a median of 39 min (IQR: 25-57) (p = .0071). For the group of patients with seizure cluster, the time from arrival to the first non-benzodiazepine antiseizure medication decreased from a median of 296 min (IQR: 112.5-409) to a median of 72 min (IQR: 46-111) (p < .001). The seizure code significantly decreased the risk of inappropriate benzodiazepine use (p = .0087), in-hospital seizure recurrence (p < .001), in-hospital mortality (p = .0074), and prolonged hospitalizations (more than 48 h) (p = .0475)., Significance: The seizure code shortens the time to treatment, reduces the length of hospital stay, decreases the risk of inappropriate benzodiazepine use, and lowers both the in-hospital seizure recurrence and in-hospital mortality among patients with urgent epileptic seizures., (© 2024 International League Against Epilepsy.)
- Published
- 2024
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39. Use of artisanal and non-regulated cannabis-based products for the treatment of epilepsy in a low-income population.
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Espinosa-Jovel C, Riveros S, Acosta-Amaya A, and García C
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Introduction: Several artisanal and non-regulated cannabis-based products used for the treatment of epilepsy are available and can be easily obtained. Many of these preparations lack proper quality validation and exhibit cannabinoid contents significantly different from those stated on their labels, along with the presence of potentially harmful compounds. This study aims to evaluate the frequency of use and prescription patterns of these products among patients with epilepsy from a low-income population., Methods: Observational and cross-sectional study. A survey was conducted on patients with epilepsy at a public hospital in Bogotá, Colombia., Results: A total of 380 patients were evaluated, with 10.3 % (n = 39) reporting the use of artisanal and non-regulated cannabis-based products for the treatment of epilepsy. Among these patients, 84.6 % (n = 33) used the product on their own initiative, without a medical recommendation. Only 7.7 % (n = 3) of the patients had a record of the consumption of these products in their medical history. Age (p = 0.002), type of therapeutic response (p = 0.01), number of previous antiseizure medications used (p < 0.01), and non-pharmacological treatment such as vagal nerve stimulation (p < 0.01) showed a statistically significant association with the utilization of these products., Conclusion: One in ten patients with epilepsy has used artisanal and non-regulated cannabis-based products for the treatment of their condition. The majority of patients used these products on their own initiative, without a medical recommendation. The prevalence of consuming these products was higher among younger individuals with uncontrolled epilepsy, who had previously used multiple antiseizure medications and other non-pharmacological alternatives such as vagal nerve stimulation., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Published
- 2024
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40. Laparoscopic extended right colectomy with complete mesocolic excision and en bloc partial gastrectomy for locally advanced mid-transverse colon cancer-A video vignette.
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Vela J, Riquoir C, Palacios F, Riveros S, Larach JT, and Besser N
- Published
- 2024
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41. Impact of Third-Generation Antiseizure Medications on People with Epilepsy in a Low-Income Population: The Brivaracetam Experience in a Real-World Study.
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Espinosa-Jovel C, Valencia N, Gaitán L, and Riveros S
- Abstract
Background: Third-generation antiseizure medications, such as brivaracetam, are recognized for their superior safety, tolerability, and pharmacokinetic profiles. However, their potential benefits are often limited in low-income populations because of challenges related to availability and affordability., Objective: We aimed to evaluate the effectiveness and safety of brivaracetam for treating epilepsy in a low-income population, within a real-world setting., Methods: This retrospective cohort study included individuals with epilepsy from a low-income population in Bogotá, Colombia, who were treated with brivaracetam between January 2020 and July 2023. Effectiveness (mean seizure reduction and ≥ 50% seizure reduction) and safety (retention rate and adverse events) were evaluated., Results: A total of 106 individuals were included, with a median age of 33 years (interquartile range: 24-44). Most had focal epilepsy with a median disease duration of 25.4 years (standard deviation: 13.6). The baseline seizure frequency was 4 seizures per month (interquartile range: 2-15) and individuals had previously received a mean of 4.4 (standard deviation: 1.8) antiseizure medications. The mean percentage seizure reduction at 3, 6, and 12 months was 55.3%, 66.9%, and 63.8%, respectively. Additionally, 60%, 63.8%, and 65.9% of individuals achieved a ≥ 50% seizure reduction at 3, 6, and 12 months, respectively. Retention rate at 3 months was 89% (n = 95) and 18.7% (n = 20) reported adverse effects., Conclusions: In a real-world setting, brivaracetam has been shown to be safe and effective for the treatment of epilepsy in individuals from a low-income population. This study suggests that people with epilepsy living in this context can significantly benefit from the use of third-generation antiseizure medications., (© 2024. The Author(s).)
- Published
- 2024
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42. Real-world evidence on the use of cannabidiol for the treatment of drug resistant epilepsy not related to Lennox-Gastaut syndrome, Dravet syndrome or Tuberous Sclerosis Complex.
- Author
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Espinosa-Jovel C, Riveros S, Bolaños-Almeida C, Salazar MR, Inga LC, and Guío L
- Subjects
- Humans, Young Adult, Adult, Anticonvulsants adverse effects, Retrospective Studies, Seizures drug therapy, Cannabidiol, Lennox Gastaut Syndrome drug therapy, Drug Resistant Epilepsy drug therapy, Tuberous Sclerosis complications, Tuberous Sclerosis drug therapy, Epilepsies, Myoclonic drug therapy
- Abstract
Introduction: Highly purified cannabidiol (CBD) has a broad spectrum of action and could be useful for the treatment of drug resistant epilepsy regardless of etiology or syndrome., Materials and Methods: Multicenter retrospective study that evaluated the efficacy and safety of CBD for the treatment of drug resistant epilepsy of different etiologies in patients >2 years of age., Results: Seventy-eight patients with a median age of 24 years and a wide spectrum of mainly structural and genetic etiologies were included. Patients were using a median of 3 antiseizure drugs (IQR=2-4) and had a median of 30 monthly seizures (IQR=12-100) before starting CBD. The median treatment time with CBD was 14 months (IQR=10-17). The efficacy analysis at the last available visit showed that mean percent reduction in seizures, ≥50% reduction in seizure frequency and seizure freedom was 67.8%, 68.8% and 11.5% respectively. We found no significant impact of concomitant clobazam use on the efficacy and safety of CBD. In the safety analysis, 28.2% (n = 22) of patients presented adverse events related to CBD and drug-retention rate was 78.2%., Conclusions: In a real-world setting, highly purified CBD has been shown to be safe and effective for the treatment of drug resistant epilepsy not related to Lennox-Gastaut syndrome, Dravet syndrome or Tuberous Sclerosis Complex. Based on these findings, highly purified CBD should be considered as an adjuvant therapy for drug resistant epilepsy, regardless of its underlying cause or specific syndrome. Nevertheless, this assumption should be validated through further controlled trials., Competing Interests: Declaration of Competing Interest No conflicts of interest exist., (Copyright © 2023. Published by Elsevier Ltd.)
- Published
- 2023
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43. Customized normothermic machine perfusion decreases ischemia-reperfusion injury compared with static cold storage in a porcine model of liver transplantation.
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Riveros S, Marino C, Ochoa G, Soto D, Alegría L, Zenteno MJ, San Martín S, Brañes A, Achurra P, and Rebolledo R
- Subjects
- Swine, Animals, Organ Preservation methods, Perfusion methods, Bile, Liver surgery, Liver pathology, Liver Transplantation adverse effects, Liver Transplantation methods, Reperfusion Injury etiology, Reperfusion Injury prevention & control, Reperfusion Injury pathology
- Abstract
Background: Liver transplantation has been demonstrated to be the best treatment for several liver diseases, while grafts are limited. This has caused an increase in waiting lists, making it necessary to find ways to expand the number of organs available for transplantation. Normothermic perfusion (NMP) of liver grafts has been established as an alternative to static cold storage (SCS), but only a small number of perfusion machines are commercially available., Methods: Using a customized ex situ machine perfusion, we compared the results between ex situ NMP and SCS preservation in a porcine liver transplant model., Results: During NMP, lactate concentrations were 80% lower after the 3-h perfusion period, compared with SCS. Bile production had a 2.5-fold increase during the NMP period. After transplantation, aspartate transaminase (AST) and alanine transaminase (ALT) levels were 35% less in the NMP group, compared to the SCS group. In pathologic analyses of grafts after transplant, tissue oxidation did not change between groups, but the ischemia-reperfusion injury score was lower in the NMP group., Conclusion: NMP reduced hepatocellular damage and ischemia-reperfusion injury when compared to SCS using a customized perfusion machine. This could be an alternative for low-income countries to include machine perfusion in their therapeutic options., (© 2022 International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.)
- Published
- 2023
- Full Text
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44. Right Lobe Liver Donation After Bariatric Surgery. A Case Series of 4 Living Donors.
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Garcia D, Riveros S, Ochoa G, Rebolledo P, Achurra P, Briceño E, Viñuela E, Arab JP, Jarufe N, Fernandes E, Martinez J, and Dib M
- Subjects
- Male, Female, Humans, Middle Aged, Adult, Living Donors, Retrospective Studies, Weight Loss, Treatment Outcome, Gastrectomy adverse effects, Liver surgery, Obesity, Morbid surgery, Liver Transplantation adverse effects, Laparoscopy adverse effects, Bariatric Surgery adverse effects, Gastric Bypass adverse effects
- Abstract
Background: The increasing prevalence of obesity and need for bariatric surgery as well as the expanding use of living donors for liver transplantation means that potential donors could present with this surgical history. We present 4 cases of liver donors with previous bariatric surgery in our living donor liver transplant program., Methods: A retrospective descriptive analysis of patients with a bariatric surgery history who underwent right hepatectomy in our living donor liver transplant program is presented., Results: Case 1: A 53-year-old man with body mass index (BMI) of 33 who underwent laparoscopic sleeve gastrectomy (LSG). Pretransplant BMI was 21.5. Case 2: A 46-year-old woman with a BMI maximum of 40.8 who underwent LSG and required conversion to Roux-en-Y gastric bypass. Pretransplant BMI was 35.1. Case 3: A 53-year-old woman with a BMI maximum of 31.6 who underwent LSG. Pretransplant BMI was 24.2. Case 4: A 38-year-old man with a BMI maximum of 41.5 who underwent Roux-en-Y gastric bypass 6 years before the hepatectomy. Pretransplant BMI was 29.4. No complications were observed. Average operative time was 367.5 minutes, with a hospital stay of 5.8 days and 100% graft survival to date., Discussion: Utilization of selected donors with previous bariatric surgery appears to be a safe option and increases the donor pool., (Copyright © 2022 Elsevier Inc. All rights reserved.)
- Published
- 2022
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45. Midterm Results of the Open and Minimally Invasive Transversus Abdominis Release Technique for the Treatment of Abdominal Wall Hernias in an Academic Center.
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Quezada N, Grimoldi M, Jacubovsky I, Besser N, Riveros S, Achurra P, and Crovari F
- Abstract
Introduction: Large hernia defects are a challenge for general and specialized hernia surgeons. The transversus abdominis release (TAR) technique has revolutionized the treatment of complex hernias since it allows the closure of large midline hernias, as well as hernias in different locations. This study aims to report the experience with the TAR technique and mid-term results in the first 101 patients. Methods: Non-concurrent cohort review of our prospectively collected electronic database. All patients submitted to a TAR (open or minimally invasive eTEP-TAR) from 2017 to 2020 were included. Demographic data, comorbidities, hernia characteristics, preoperative optimization, intraoperative variables, and clinical outcomes were gathered. The main outcomes of this study are hernia recurrences and surgical morbidity. Results: A total of 101 patients were identified. The median follow-up was 26 months. Mean age and body mass index was 63 years and 31.4 Kg/m
2 , respectively. Diabetes was present in 22% of patients and 43% had at least one previous hernia repair. Nineteen patients had significant loss of domain. Mean hernia size and area were 13 cm and 247 cm2 , respectively. Ninety-six percent of cases were clean or clean-contaminated. The mean operative time was 164 min and all patients received a synthetic mesh. We diagnosed two hernia recurrences and the overall (medical and surgical) complication rate was 32%. The hernia-specific complication rate was 17%, with seven surgical site infections and seven surgical site occurrences requiring procedural interventions. Notably, weight loss was associated with a lower risk of SSOPI and reoperations. Conclusion: We show an encouraging 2% of recurrences in the mid-term follow-up in the setting of clinically complex hernia repair. However, we observed a high frequency of overall and hernia-specific complications pointing to the complexity of the type of surgery itself and the patients we operated on., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Quezada, Grimoldi, Jacubovsky, Besser, Riveros, Achurra and Crovari.)- Published
- 2022
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46. Implementation and design of customized ex vivo machine perfusion. Analysis of its first results.
- Author
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Riveros S, Marino C, Ochoa G, Morales E, Soto D, Alegría L, Zenteno MJ, Brañes A, Achurra P, and Rebolledo RA
- Subjects
- Animals, Equipment Design, Female, Hemodynamics, Liver blood supply, Liver Transplantation, Swine, Liver metabolism, Organ Preservation methods, Perfusion instrumentation
- Abstract
The lack of organs available for transplantation is a global problem. The high mortality rates on the waiting list and the high number of discarded livers are reasons to develop new tools in the preservation and transplantation process. New tools should also be available for low-income countries. This article reports the development of customized normothermic machine perfusion (NMP). An ex vivo dual perfusion machine was designed, composed of a common reservoir organ box (CRO), a centrifugal pump (portal system, low pressure), and a roller pump (arterial system, high pressure). Porcine livers (n = 5) were perfused with an oxygenated normothermic (37℃) strategy for 3 hours. Hemodynamic variables, metabolic parameters, and bile production during preservation were analyzed. Arterial and portal flow remain stable during perfusion. Total bilirubin production was 11.25 mL (4-14.5) at 180 minutes. The median pH value reached 7.32 (7.25-7.4) at 180 minutes. Lactate values decreased progressively to normalization at 120 minutes. This perfusion setup was stable and able to maintain the metabolic activity of a liver graft in a porcine animal model. Design and initial results from this customized NMP are promising for a future clinical application in low-income countries., (© 2021 International Center for Artificial Organs and Transplantation and Wiley Periodicals LLC.)
- Published
- 2022
- Full Text
- View/download PDF
47. Development of a Novel Perfusable Solution for ex vivo Preservation: Towards Photosynthetic Oxygenation for Organ Transplantation.
- Author
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Veloso-Giménez V, Escamilla R, Necuñir D, Corrales-Orovio R, Riveros S, Marino C, Ehrenfeld C, Guzmán CD, Boric MP, Rebolledo R, and Egaña JT
- Abstract
Oxygen is the key molecule for aerobic metabolism, but no animal cells can produce it, creating an extreme dependency on external supply. In contrast, microalgae are photosynthetic microorganisms, therefore, they are able to produce oxygen as plant cells do. As hypoxia is one of the main issues in organ transplantation, especially during preservation, the main goal of this work was to develop the first generation of perfusable photosynthetic solutions, exploring its feasibility for ex vivo organ preservation. Here, the microalgae Chlamydomonas reinhardtii was incorporated in a standard preservation solution, and key aspects such as alterations in cell size, oxygen production and survival were studied. Osmolarity and rheological features of the photosynthetic solution were comparable to human blood. In terms of functionality, the photosynthetic solution proved to be not harmful and to provide sufficient oxygen to support the metabolic requirement of zebrafish larvae and rat kidney slices. Thereafter, isolated porcine kidneys were perfused, and microalgae reached all renal vasculature, without inducing damage. After perfusion and flushing, no signs of tissue damage were detected, and recovered microalgae survived the process. Altogether, this work proposes the use of photosynthetic microorganisms as vascular oxygen factories to generate and deliver oxygen in isolated organs, representing a novel and promising strategy for organ preservation., Competing Interests: Author CG was employed by company Sky-Walker SpA. Competing Interests: JTE is CSO and co-founder of SymbiOx Inc., a start-up company that owns IP in the field of this work. Thanks to an R and D grant provided by the Chilean Ministry of Economics (CORFO), during the conduct of this project, DN, RE and RC-O were full-time employees of SymbiOx Inc. All other authors declare that they have no competing interests., (Copyright © 2021 Veloso-Giménez, Escamilla, Necuñir, Corrales-Orovio, Riveros, Marino, Ehrenfeld, Guzmán, Boric, Rebolledo and Egaña.)
- Published
- 2021
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48. Epidemiological Indicators of SARS-CoV-2 (COVID-19) and Vaccination Effectiveness on the Report of Positive Cases in the Colombian Army.
- Author
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Duque MC, Correa-Cárdenas CA, Londoño-Méndez S, Oliveros C, Pérez J, Daza CD, Albarracin L, Márquez EK, Alvarado MT, Ortíz FLS, Romero Y, Gutierrez-Riveros S, and Méndez C
- Abstract
The description of the epidemiological indicators of SARS-CoV-2 (COVID-19), such as the mortality rate (MR), the case fatality rate (CFR), and the attack rate (AR), as well as the geographical distribution and daily case reports, are used to evaluate the impact that this virus has had within the Colombian Army and its health system. As military forces around the world represent the force that defends sovereignty, independence, the integrity of the national territory, and the constitutional order, while maintaining migration controls in blocked border areas during this critical pandemic times, they must carry out strict epidemiological surveillance to control the situation among the servicemen. Up to date, the Colombian Army has faced a very high attack rate (AR = 8.55%) due, among others, to living conditions where active military personnel share bedrooms, bathrooms, and dining facilities, which facilitate the spread of the virus. However, being a mainly young and healthy population, the MR was 1.82 deaths/1,000 ha, while the CFR = 2.13% indexes consistently low if compared with those values reported for the national population. In addition, the effectiveness of vaccination is shown in daily cases of COVID-19, where, for the third peak, the active military population presented a decrease of positive patients compared to the dynamics of national transmission and the total population of the military forces (active, retired, and beneficiaries)., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Duque, Correa-Cárdenas, Londoño-Méndez, Oliveros, Pérez, Daza, Albarracin, Márquez, Alvarado, Ortíz, Romero, Gutierrez-Riveros and Méndez.)
- Published
- 2021
- Full Text
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49. Cluster characterization of SARS-CoV-2 in military personnel deployed to Egypt and subsequent introduction of B.1.1.7 and C.36 lineages to Colombia.
- Author
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Ballesteros N, Castañeda S, Muñoz M, Patiño LH, Méndez C, Oliveros C, Pérez J, Albarracín L, Márquez EK, Alvarado MT, Santos Ortiz FL, Romero Y, Correa-Cárdenas CA, Duque MC, Gutíerrez-Riveros S, Paniz-Mondolfi A, and Ramírez JD
- Subjects
- Colombia epidemiology, Egypt epidemiology, Humans, COVID-19 virology, Military Personnel, SARS-CoV-2 classification
- Published
- 2021
- Full Text
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50. Cutibacterium Acnes Tetracycline Resistance Profile in Patients with Acne Vulgaris, in a Colombian Dermatologic Center.
- Author
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Castellanos Lorduy HJ, Pérez Cely HC, Casadiego Rincón EJ, Henao Riveros SC, and Colorado CL
- Abstract
Introduction: Acne is a chronic inflammatory disease, in which different events intervene in its pathogenesis, one of which is Cutibacterium acnes (C. acnes). Resistance of this bacteria to different antimicrobials used in treatment has been described in different regions of the world. The purpose of the study is to estimate the resistance of C. acnes to cyclins in patients with moderate and severe acne over 18 years of age., Materials and Methods: An analytical cross-sectional study was carried out. Samples were taken from inflammatory lesions with a comedone extractor. The content of the samples was incubated in an anaerobic atmosphere to grow C. acnes. Finally, the susceptibility of C. acnes to tetracycline, minocycline and doxycycline was determined., Results: Samples were taken from 147 patients, of which 129 showed growth of C. acnes, finding that 5.43% of the strains were resistant to tetracycline, 5.43% to doxycycline, 0.78% to minocycline and cross resistance between doxycycline and tetracycline in all the cases. An association was found between resistance and being 25 years of age or older. No association was found with the prior use of antibiotics, a history of misuse of oral or topical antibiotics, and other demographic and clinical characteristics evaluated., Conclusions: The resistance found of C. acnes to cyclines was lower than that reported in other studies. Although no relationship was found with the previous use of antibiotics, it is a factor described in previous studies, which is why the proper use of antibiotics is imperative to avoid the appearance of resistance., (Copyright © 2021 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2021
- Full Text
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