10 results on '"Riza Boranbayeva"'
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2. Epidemiology of congenital malformations in Kazakhstan
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Altynay SADYKOVA, Riza BORANBAYEVA, Gulbanu BERDIYAROVA, Karligash ZHUBANYSHEVA, Svetlana ANOHINA, Mukhtar KULIMBET, Dinara OSPANOVA, Shynar TANABAYEVA, and Ildar FAKHRADIYEV
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congenital malformations ,epidemiology ,prevalence ,kazakhstan ,Medicine ,Medicine (General) ,R5-920 - Abstract
Introduction. Congenital malformations are the main cause of morbidity and mortality amongst newborns. The detailed epidemiological data about congenital anomalies in Kazakhstan have not been reported yet. The objective of the study was to estimate the prevalence of congenital malformations and their regional distribution in Kazakhstan. In addition, the study aimed to assess the cause-specific death rate, perinatal, neonatal, post-neonatal, and infant mortality rates for the period 2015-2019. Material and methods. The descriptive cross-sectional study was based on data obtained from the Republican Centre of Health Development (18 regions of Kazakhstan) for the period 2015-2019. Results. In 2019, the prevalence of total congenital malformations decreased by 30-40% compared to 2015. At the same time, the prevalence of congenital malformations of the respiratory system increased by 14%. The congenital cardiovascular malformations prevailed (18.3 per 10,000 live births) in 2015. The highest values of mortality from congenital malformations were observed in South Kazakhstan. In 2019, the rates of perinatal (13.14), post-neonatal (3.89), neonatal (4.32), and infant mortality (8.21) per 10,000 live births showed a slight decrease. In 2019, an increase of perinatal mortality was observed compared to 2015 (from 13.96 to 14.29 per 10,000 live births), while neonatal mortality decreased from 8.33 to 6.08 per 10,000 live births, as well as infant mortality (from 11.33 to 9.42 per 10,000 live births). Conclusions. During the 5-year period of the study, the analysis showed a decrease in the prevalence of some congenital malformations, such as malformations of digestive, urinary, nervous systems, and others. In the southern region of Kazakhstan there was a high rate of different forms of congenital defects, in particular, the circulatory system abnormalities. The results can be useful for the optimization of the national strategy, to reduce the prevalence of congenital malformations.
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- 2021
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3. COMPARATIVE ANALYSIS OF CLINICAL AND LABORATORY DATA IN CHILDREN WITH MULTISYSTEM INFLAMMATORY SYNDROME ASSOCIATED WITH SARS-COV-2 IN THE REPUBLIC OF KAZAKHSTAN
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Indira Jaxybayeva, Riza Boranbayeva, Sagira Abdrakhmanova, Raikhan Maitbassova, Pakhitkanym Ishuova, Dinagul Bayesheva, Nurila Maltabarova, Adyl Katarbayev, Kumisgul Umesheva, Tatyana Marshalkina, Lyazat Manzhuova, Gulnara Abdilova, Gulshat Alimkhanova, Gulmira Yerzhanova, Gulnara Bulabaeva, Nazgul Zhanuzakova, Svetlana Anokhina, Aigul Kuatbayeva, and Gulnara Tashenova
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paediatrics, MIS-C, SARS-CoV-2, Delta variant ,Diseases of the blood and blood-forming organs ,RC633-647.5 - Abstract
Background and Objectives: Data with more severe mutations of the SARS-CoV-2 virus, compared with the original wild-type strain of COVID-19 disease, were reported worldwide. The study aims to describe the clinical and laboratory manifestations of a multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2 in the Republic of Kazakhstan and to compare the severity of the disease depending on the time of the circulating variant of SARS-CoV-2 virus. Material and methods: A retrospective, multicentre, nationwide study of 89 children with MIS-C who received inpatient treatment from August 1, 2020, to December 1, 2021. The patients were allocated into two groups: 1(2020) - 45 children and 2 (2021) - 44 children. Study periods were characterized by the circulation of different strains of the SARS-CoV-2 virus. Results: In children with MIS-C in 2021, acute renal failure, disseminated intravascular coagulation syndrome, and shock were statistically more frequently found, which led to fairly common admittance to the intensive care unit. When comparing laboratory data, the children with MIS-C in 2021 had higher values of inflammation markers: ferritin, procalcitonin, erythrocyte sedimentation rate, leukocytes, and neutrophils. Furthermore, these children had a lower level of lymphocytes than children with MIS-C in 2020. Conclusions: MIS-C is a severe, life-threatening systemic disease characterized by multiple organ damage and important inflammatory changes in laboratory parameters. A more aggressive clinical course of MIS-C in 2021 may be associated with the emergence of new SARS-CoV-2 strains. Keywords: children, MIS-C, variants of SARS-CoV-2
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- 2022
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4. Current issues of gastro-oesophageal reflux disease surgical treatment in children
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Nurlan Nurkinovich Akhparov, Riza Boranbayeva, Saule Bakhtyarovna Suleimanova, and Madina Temirkhanova
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children ,oesophagitis ,oesophagofundoplication ,gastro-oesophageal reflux ,Pediatrics ,RJ1-570 ,Surgery ,RD1-811 - Abstract
Gastro-oesophageal reflux (GER) disease is one of the most common diseases amongst a wide range of chronic inflammatory diseases of the gastrointestinal tract in children of all ages, significantly impairing the quality of life of the child and posing a serious threat to the health of the patient. From 2008 to 2019, 134 patients aging from 6 months to 12 years were hospitalised at the Scientific Center for Pediatrics and Pediatric Surgery including 69 (51%) infants. Of them, 51 (38%) were the patients with persistent manifestations of regurgitation, despite an outpatient course of conservative therapy; 29 (22%) patients with recurrent reflux-associated pneumonia; also, 35 (26%) children with GER in the structure of the main pathology of the central nervous system, as well as 19 (14%) patients after surgery of the anastomosis of the oesophagus with its atresia. One hundred and seven (79.8%) patients underwent surgery. Nissen oesophagofundoplication was traditionally performed in 41 (38%) patients, in combination with Stamm gastrostomy in 14 (34%), with Mikulich pyloroplasty in 9 (22%) and in combination with gastrostomy and pyloroplasty in 12 (29%) children. Laparoscopic Nissen oesophagofundoplication was used in 16 (15%) cases. Thall oesophagofundoplication was performed in 48 (45%) patients, while in two (2%) cases, Boerema gastropexy was conducted. The immediate results were studied in all 107 patients. Complications in the form of gastric distress syndrome were revealed in four (3.7%) patients who did not undergo pyloroplasty, which in two (1.9%) cases required additional surgery of the stomach draining, whereas in the other two (1.9%) patients, the distress syndrome was stopped conservatively. A dumping syndrome was identified in two (1.9%) patients. Timely recognition of the pathological process, its nature and prevalence determines the indications for the use of various methods of operation, which are based on an individual approach to each patient.
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- 2021
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5. Respiratory Dysfunction in Children and Adolescents with Mucopolysaccharidosis Types I, II, IVA, and VI
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Assel Tulebayeva, Maira Sharipova, and Riza Boranbayeva
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mucopolysaccharidosis ,respiratory dysfunction ,pulmonary dysfunction ,enzyme-replacement therapy ,kazakhstan ,Medicine (General) ,R5-920 - Abstract
Mucopolysaccharidosis (MPS) is a rare genetic disease involving active storage of glycosaminoglycans (GAGs). Accumulation of GAGs in the connective tissues of airways leads to progressive pulmonary dysfunction. Studies conducted in Taiwan revealed mainly restrictive pulmonary dysfunction, whereas the same studies in Egypt and California revealed obstructive pulmonary dysfunction. The contradictory results and lack of studies of respiratory system in patients with MPS in Asian populations are an indication to study pulmonary impairment in patients with MPS in Kazakhstan. The prospective study of respiratory system in patients with MPS was conducted in the Scientific Centre of Paediatrics and Paediatric Surgery. Patients with MPS (n = 11) were examined for respiratory function. Different types of pulmonary dysfunction were present in MPS patients, they were mainly of a restrictive pathology. One patient with MPS II had obstructive dysfunction. Enzyme replacement therapy was provided for an average duration of four years, leading to improvements in respiratory function in two patients with total normalization in one. All observed patients had respiratory dysfunction, mainly of the restrictive type. Pulmonary impairment in patients with MPS is the main reason for death. Thus, it is necessary to follow up with pulmonary function assessments in children with MPS.
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- 2020
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6. Epidemiology of congenital malformations in Kazakhstan
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Shynar Tanabayeva, Svetlana Anohina, Gulbanu Berdiyarova, Riza Boranbayeva, Mukhtar Kulimbet, Altynay Sadykova, Ildar Fakhradiyev, Karligash Zhubanysheva, and Dinara Ospanova
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Pediatrics ,medicine.medical_specialty ,Medicine (General) ,business.industry ,prevalence ,Congenital malformations ,General Medicine ,R5-920 ,Epidemiology ,medicine ,Medicine ,epidemiology ,business ,kazakhstan ,congenital malformations - Abstract
Introduction. Congenital malformations are the main cause of morbidity and mortality amongst newborns. The detailed epidemiological data about congenital anomalies in Kazakhstan have not been reported yet. The objective of the study was to estimate the prevalence of congenital malformations and their regional distribution in Kazakhstan. In addition, the study aimed to assess the cause-specific death rate, perinatal, neonatal, post-neonatal, and infant mortality rates for the period 2015-2019. Material and methods. The descriptive cross-sectional study was based on data obtained from the Republican Centre of Health Development (18 regions of Kazakhstan) for the period 2015-2019. Results. In 2019, the prevalence of total congenital malformations decreased by 30-40% compared to 2015. At the same time, the prevalence of congenital malformations of the respiratory system increased by 14%. The congenital cardiovascular malformations prevailed (18.3 per 10,000 live births) in 2015. The highest values of mortality from congenital malformations were observed in South Kazakhstan. In 2019, the rates of perinatal (13.14), post-neonatal (3.89), neonatal (4.32), and infant mortality (8.21) per 10,000 live births showed a slight decrease. In 2019, an increase of perinatal mortality was observed compared to 2015 (from 13.96 to 14.29 per 10,000 live births), while neonatal mortality decreased from 8.33 to 6.08 per 10,000 live births, as well as infant mortality (from 11.33 to 9.42 per 10,000 live births). Conclusions. During the 5-year period of the study, the analysis showed a decrease in the prevalence of some congenital malformations, such as malformations of digestive, urinary, nervous systems, and others. In the southern region of Kazakhstan there was a high rate of different forms of congenital defects, in particular, the circulatory system abnormalities. The results can be useful for the optimization of the national strategy, to reduce the prevalence of congenital malformations.
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- 2021
7. Pediatric Extracranial Germ Cell Tumors: Expression of microRNA
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Symbat Saliyeva, Riza Boranbayeva, Natalya Konoplya, Minira Bulegenova, Olga Blau, Vyacheslav Belousov, Joanna Granica, Dina Mukushkina, and Gulmira Altynbayeva
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Oncology ,Pediatrics, Perinatology and Child Health ,Hematology - Abstract
Germ cell tumors (GCTs) may occur from the neonatal period to late adulthood, characterized by extensive clinical and pathologic heterogeneity. MicroRNAs are a family of small noncoding RNAs that regulate a wide array of biological processes including carcinogenesis. MicroRNAs may be used for many purposes in clinical diagnostics. Numerous studies have proven the diagnostic value of microRNA371-373 and microRNA302/367 expression in malignant GCT. The diagnostic value of microRNA375 is disputable, because while its value is confirmed by some research data, there are still others denying it.The results of our own research on the relative expression of 10 microRNAs, including microRNA375, associated with GCT in the tumor tissues of 84 children and adolescents are presented.In our research, overexpression of microRNA 371-373, 302/367 detected in the group of malignant GCT subtypes. Statistically significant expression of microRNA375 have been defined not only in the group of malignant GCT subtypes, but also in the group of immature teratomas. Among malignant GCTs, high expression of microRNA375 is specific for yolk sac tumors. In the group of seminomas, embryonic carcinomas, and mature teratomas expression of microRNA375 was observed imperceptible, even so the results were statistically insignificant.Expression of microRNA 371-373, 302/367 is representative of malignant GCT subtypes. Statistically significant and high expression of microRNA375 attributable for yolk sac tumors and immature teratomas.
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- 2021
8. Global characteristics and outcomes of SARS-CoV-2 infection in children and adolescents with cancer (GRCCC): a cohort study
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Sheena Mukkada, Nickhill Bhakta, Guillermo L Chantada, Yichen Chen, Yuvanesh Vedaraju, Lane Faughnan, Maysam R Homsi, Hilmarie Muniz-Talavera, Radhikesh Ranadive, Monika Metzger, Paola Friedrich, Asya Agulnik, Sima Jeha, Catherine Lam, Rashmi Dalvi, Laila Hessissen, Daniel C Moreira, Victor M Santana, Michael Sullivan, Eric Bouffet, Miguela A Caniza, Meenakshi Devidas, Kathy Pritchard-Jones, Carlos Rodriguez-Galindo, A Juan Ribelles, Adriana Balduzzi, Alaa Elhaddad, Alejandra Casanovas, Alejandra Garcia Velazquez, Aliaksandra Laptsevich, Alicia Chang, Alessandra Lamenha F. Sampaio, Almudena González Prieto, Alvaro Lassaletta, Amaranto Suarez M, Ana Patricia Alcasabas, Anca Colita, Andres Morales La Madrid, Angélica Samudio, Annalisa Tondo, Antonella Colombini, Antonis Kattamis, N Araceli Lopez Facundo, Arpita Bhattacharyya, Aurélia Alimi, Aurélie Phulpin, Barbora Vakrmanova, Basak A Aksoy, Benoit Brethon, Jator Brian Kobuin, Carla Nolasco Monteiro, Catherine Paillard, Catherine Vezina, Bozkurt Ceyhun, Cristiana Hentea, Cristina Meazza, Daniel Ortiz-Morales, Roque Daniel Solorzano, Daniela Arce Cabrera, Daniele Zama, Debjani Ghosh, Diana Ramírez-Rivera, Doris A Calle Jara, Dragana Janic, Elianneth Rey Helo, Elodie Gouache, Enmanuel Guerrero Quiroz, Enrique Lopez, Eric Thebault, Essy Maradiegue, Eva de Berranger, Fatma S E Ebeid, Federica Galaverna, Federico Antillon-Klussmann, Felipe Espinoza Chacur, Fernando Daniel Negro, Francesca Carraro, Francesca Compagno, Francisco Barriga, Gabriela Tamayo Pedraza, Gissela Sanchez Fernandez, Gita Naidu, Gülnur Tokuc, Hamidah Alias, Hannah Grace B Segocio, Houda Boudiaf, Imelda Asetre Luna, Iris Maia, Itziar Astigarraga, Ivan Maza, Jacqueline E Montoya Vásquez, Janez Jazbec, Jelena Lazic, Jeniffer Beck Dean, Jeremie Rouger-Gaudichon, Johanny Carolina Contreras González, Jorge Huerta Aragonés, José L Fuster, Juan Quintana, Julia Palma, Karel Svojgr, Karina Quintero, Karolina Malic Tudor, Kleopatra Georgantzi, Kris Ann P Schultz, Laura Ureña Horno, Lidia Fraquelli, Linda Meneghello, Lobna Shalaby, Lola L Macias Mora, Lorna A Renner, Luciana Nunes Silva, Luisa Sisinni, Mahmoud Hammad, M Fernández Sanmartín, C Marcela Zubieta A, María Constanza Drozdowski, Maria Kourti, Marcela María Palladino, Maria R Miranda Madrazo, Marilyne Poiree, Marina Popova, Mario Melgar, Marta Baragaño, Martha J Avilés-Robles, Massimo Provenzi, Mecneide Mendes Lins, Mehmet Fatih Orhan, Milena Villarroel, Mónica Jerónimo, Mónica Varas Palma, Muhammad Rafie Raza, Mulindwa M Justin, Najma Shaheen, Nerea Domínguez-Pinilla, Nicholas S Whipple, Nicolas André, Ondrej Hrusak, Pablo Velasco Puyó, Pamela Zacasa Vargas, Paola Olate Mellado, Pascale Yola Gassant, Paulina Diaz Romero, Raffaella De Santis, Rejin Kebudi, Riza Boranbayeva, Roberto Vasquez, Romel A. Segura, Roy Enrique Rosado, Sandra Gómez, Sandra Raimbault, Sanjeeva Gunasekera, Sara M Makkeyah, Sema Buyukkapu Bay, Sergio M Gómez, Séverine Bouttefroy, Shahnoor Islam, Sherif Abouelnaga, Silvio Fabio Torres, Simone Cesaro, Sofia Nunes, Soraia Rouxinol, Sucharita Bhaumik, Symbat Saliyeva, Tamara Inostroza, Thelma Velasquez, Tint Myo Hnin, Ulrika Norén-Nyström, Valentina Baretta, Yajaira Valentine Jimenez-Antolinez, Vanesa Pérez Alonso, Vanessa Ayer Miller, Virginie Gandemer, Viviana Lotero, Volha Mishkova, Wendy Gómez-García, Yeva Margaryan, Yumna Syed, Mukkada S., Bhakta N., Chantada G.L., Chen Y., Vedaraju Y., Faughnan L., Homsi M.R., Muniz-Talavera H., Ranadive R., Metzger M., Friedrich P., Agulnik A., Jeha S., Lam C., Dalvi R., Hessissen L., Moreira D.C., Santana V.M., Sullivan M., Bouffet E., Caniza M.A., Devidas M., Pritchard-Jones K., Rodriguez-Galindo C., Ribelles A.J., Balduzzi A., Elhaddad A., Casanovas A., Garcia Velazquez A., Laptsevich A., Chang A., F. Sampaio A.L., Gonzalez Prieto A., Lassaletta A., Suarez M A., Alcasabas A.P., Colita A., Morales La Madrid A., Samudio A., Tondo A., Colombini A., Kattamis A., Lopez Facundo N.A., Bhattacharyya A., Alimi A., Phulpin A., Vakrmanova B., Aksoy B.A., Brethon B., Kobuin J.B., Nolasco Monteiro C., Paillard C., Vezina C., Ceyhun B., Hentea C., Meazza C., Ortiz-Morales D., Solorzano R.D., Arce Cabrera D., Zama D., Ghosh D., Ramirez-Rivera D., Calle Jara D.A., Janic D., Rey Helo E., Gouache E., Guerrero Quiroz E., Lopez E., Thebault E., Maradiegue E., de Berranger E., Ebeid F.S.E., Galaverna F., Antillon-Klussmann F., Espinoza Chacur F., Negro F.D., Carraro F., Compagno F., Barriga F., Tamayo Pedraza G., Sanchez Fernandez G., Naidu G., Tokuc G., Alias H., B Segocio H.G., Boudiaf H., Asetre Luna I., Maia I., Astigarraga I., Maza I., Montoya Vasquez J.E., Jazbec J., Lazic J., Beck Dean J., Rouger-Gaudichon J., Contreras Gonzalez J.C., Huerta Aragones J., Fuster J.L., Quintana J., Palma J., Svojgr K., Quintero K., Malic Tudor K., Georgantzi K., P Schultz K.A., Urena Horno L., Fraquelli L., Meneghello L., Shalaby L., Macias Mora L.L., A Renner L., Nunes Silva L., Sisinni L., Hammad M., Fernandez Sanmartin M., Zubieta A C.M., Drozdowski M.C., Kourti M., Palladino M.M., Miranda Madrazo M.R., Poiree M., Popova M., Melgar M., Baragano M., Aviles-Robles M.J., Provenzi M., Mendes Lins M., Fatih Orhan M., Villarroel M., Jeronimo M., Varas Palma M., Rafie Raza M., M Justin M., Shaheen N., Dominguez-Pinilla N., Whipple N.S., Andre N., Hrusak O., Velasco Puyo P., Zacasa Vargas P., Olate Mellado P., Yola Gassant P., Diaz Romero P., De Santis R., Kebudi R., Boranbayeva R., Vasquez R., Segura R.A., Rosado R.E., Gomez S., Raimbault S., Gunasekera S., Makkeyah S.M., Buyukkapu Bay S., M Gomez S., Bouttefroy S., Islam S., Abouelnaga S., Torres S.F., Cesaro S., Nunes S., Rouxinol S., Bhaumik S., Saliyeva S., Inostroza T., Velasquez T., Hnin T.M., Noren-Nystrom U., Baretta V., Jimenez-Antolinez Y.V., Perez Alonso V., Ayer Miller V., Gandemer V., Lotero V., Mishkova V., Gomez-Garcia W., Margaryan Y., Syed Y., Mukkada, S, Bhakta, N, Chantada, G, Chen, Y, Vedaraju, Y, Faughnan, L, Homsi, M, Muniz-Talavera, H, Ranadive, R, Metzger, M, Friedrich, P, Agulnik, A, Jeha, S, Lam, C, Dalvi, R, Hessissen, L, Moreira, D, Santana, V, Sullivan, M, Bouffet, E, Caniza, M, Devidas, M, Pritchard-Jones, K, Rodriguez-Galindo, C, Ribelles, A, Balduzzi, A, Elhaddad, A, Casanovas, A, Garcia Velazquez, A, Laptsevich, A, Chang, A, F. Sampaio A., L, Gonzalez Prieto, A, Lassaletta, A, Suarez M, A, Alcasabas, A, Colita, A, Morales La Madrid, A, Samudio, A, Tondo, A, Colombini, A, Kattamis, A, Lopez Facundo, N, Bhattacharyya, A, Alimi, A, Phulpin, A, Vakrmanova, B, Aksoy, B, Brethon, B, Kobuin, J, Nolasco Monteiro, C, Paillard, C, Vezina, C, Ceyhun, B, Hentea, C, Meazza, C, Ortiz-Morales, D, Solorzano, R, Arce Cabrera, D, Zama, D, Ghosh, D, Ramirez-Rivera, D, Calle Jara, D, Janic, D, Rey Helo, E, Gouache, E, Guerrero Quiroz, E, Lopez, E, Thebault, E, Maradiegue, E, de Berranger, E, Ebeid, F, Galaverna, F, Antillon-Klussmann, F, Espinoza Chacur, F, Negro, F, Carraro, F, Compagno, F, Barriga, F, Tamayo Pedraza, G, Sanchez Fernandez, G, Naidu, G, Tokuc, G, Alias, H, B Segocio, H, Boudiaf, H, Asetre Luna, I, Maia, I, Astigarraga, I, Maza, I, Montoya Vasquez, J, Jazbec, J, Lazic, J, Beck Dean, J, Rouger-Gaudichon, J, Contreras Gonzalez, J, Huerta Aragones, J, Fuster, J, Quintana, J, Palma, J, Svojgr, K, Quintero, K, Malic Tudor, K, Georgantzi, K, P Schultz, K, Urena Horno, L, Fraquelli, L, Meneghello, L, Shalaby, L, Macias Mora, L, A Renner, L, Nunes Silva, L, Sisinni, L, Hammad, M, Fernandez Sanmartin, M, Zubieta A, C, Drozdowski, M, Kourti, M, Palladino, M, Miranda Madrazo, M, Poiree, M, Popova, M, Melgar, M, Baragano, M, Aviles-Robles, M, Provenzi, M, Mendes Lins, M, Fatih Orhan, M, Villarroel, M, Jeronimo, M, Varas Palma, M, Rafie Raza, M, M Justin, M, Shaheen, N, Dominguez-Pinilla, N, Whipple, N, Andre, N, Hrusak, O, Velasco Puyo, P, Zacasa Vargas, P, Olate Mellado, P, Yola Gassant, P, Diaz Romero, P, De Santis, R, Kebudi, R, Boranbayeva, R, Vasquez, R, Segura, R, Rosado, R, Gomez, S, Raimbault, S, Gunasekera, S, Makkeyah, S, Buyukkapu Bay, S, M Gomez, S, Bouttefroy, S, Islam, S, Abouelnaga, S, Torres, S, Cesaro, S, Nunes, S, Rouxinol, S, Bhaumik, S, Saliyeva, S, Inostroza, T, Velasquez, T, Hnin, T, Noren-Nystrom, U, Baretta, V, Jimenez-Antolinez, Y, Perez Alonso, V, Ayer Miller, V, Gandemer, V, Lotero, V, Mishkova, V, Gomez-Garcia, W, Margaryan, Y, and Syed, Y
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Male ,Pediatrics ,medicine.medical_specialty ,COVID-19, Children, adolescents, cancer ,Adolescent ,MEDLINE ,Severity of Illness Index ,Health systems ,Neoplasms ,purl.org/becyt/ford/3.2 [https] ,Severity of illness ,medicine ,Humans ,Child ,Children ,Pandemics ,Pandemic ,business.industry ,SARS-CoV-2 ,Risk Factor ,Infant, Newborn ,Infant ,Cancer ,COVID-19 ,Odds ratio ,Articles ,medicine.disease ,Transplantation ,Oncology ,Child, Preschool ,Cohort ,Absolute neutrophil count ,Neoplasm ,purl.org/becyt/ford/3 [https] ,Female ,Cohort Studie ,business ,Delivery of Health Care ,Human ,Cohort study - Abstract
Background: Previous studies have shown that children and adolescents with COVID-19 generally have mild disease. Children and adolescents with cancer, however, can have severe disease when infected with respiratory viruses. In this study, we aimed to understand the clinical course and outcomes of SARS-CoV-2 infection in children and adolescents with cancer. Methods: We did a cohort study with data from 131 institutions in 45 countries. We created the Global Registry of COVID-19 in Childhood Cancer to capture de-identified data pertaining to laboratory-confirmed SARS-CoV-2 infections in children and adolescents (
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- 2021
9. COVID-19 in the paediatric population of Kazakhstan
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Bayan Turdalina, Timur Saliev, Riza Boranbayeva, Dinagul Bayesheva, Talgat Nurgozhin, Shynar Tanabayeva, Ildar Fakhradiyev, and Baurzhan Zhussupov
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Male ,2019-20 coronavirus outbreak ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Adolescent ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Central asia ,medicine.disease_cause ,03 medical and health sciences ,0302 clinical medicine ,030225 pediatrics ,Epidemiology ,Medicine ,Humans ,Pediatrics, Perinatology, and Child Health ,030212 general & internal medicine ,Child ,Coronavirus ,business.industry ,SARS-CoV-2 ,Infant, Newborn ,COVID-19 ,Infant ,Virology ,Infant newborn ,Kazakhstan ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Female ,business ,Paediatric population - Abstract
Background: To date, there have been no studies of COVID-19 infection in children in Central Asia, particularly the Republic of Kazakhstan. This report analyses the epidemiological data on COVID-19...
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- 2020
10. Functional deviations of the cardiovascular system in children of the Aral Sea
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Gulzhan Kassenova, Lyaylim Nurlybay, Gulnara Tashenova, Riza Boranbayeva, and Aida Zhaksybaevna Akhenbekova
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lcsh:GE1-350 ,Pediatrics ,medicine.medical_specialty ,business.industry ,Conduction disorders ,Arterial hypotension ,Cardiac pathology ,0211 other engineering and technologies ,02 engineering and technology ,010501 environmental sciences ,01 natural sciences ,Bundle of His ,medicine.anatomical_structure ,Social assistance ,Medicine ,021108 energy ,business ,Pathological ,lcsh:Environmental sciences ,0105 earth and related environmental sciences - Abstract
The study is devoted to the influence of disadvantages of the ecological disaster region Aral Sea on the state of the cardiovascular system in children. In 55.2% of cases, autonomic dysfunction was detected, mainly in girls of pre- and puberty age (80.8%). In 39.4% of children in the Aral Sea region hypotension was diagnosed as adaptive in 81.2% and pathological hypotension in 18.8% of cases with the initial vagotonic vegetative status according to cardiointervalography (94.6%). In children with arterial hypotension, there was a decline in the quality of life due to fatigue syndrome, cephalgia, reduced activity and deterioration of cognitive abilities. Cardiac pathology was manifested in 55.2% of cases in the form of impaired automatism of the sinus node (sinus arrhythmia, tachi and bradyarrhythmias) - 54.6%, conduction disorders (incomplete blockade of the right leg of the bundle of His) in 43.3% of cases. The identified pathology shows the need to provide comprehensive medical and social assistance to the children of the Aral Sea, along with solving environmental and economic problems of the region.
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- 2020
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