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345 results on '"Rizzato, S"'

1. Broadband Parametric Amplification in DARTWARS

Author

Faverzani, M., Campana, P., Carobene, R., Gobbo, M., Ahrens, F., Avallone, G., Barone, C., Borghesi, M., Capelli, S., Carapella, G., Caricato, A. P., Callegaro, L., Carusotto, I., Celotto, A., Cian, A., D’Elia, A., Di Gioacchino, D., Enrico, E., Falferi, P., Fasolo, L., Ferri, E., Filatrella, G., Gatti, C., Giubertoni, D., Granata, V., Guarcello, C., Irace, A., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mezzena, R., Monteduro, A. G., Moretti, R., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Piedjou Komnang, A. S., Piersanti, L., Rettaroli, A., Rizzato, S., Tocci, S., Vinante, A., Zannoni, M., and Giachero, A.

Published
2024
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2. Characterization of hydrogenated amorphous silicon sensors on polyimide flexible substrate

Author

Menichelli, M., Antognini, L., Aziz, S., Bashiri, A., Bizzarri, M., Calcagnile, L., Caprai, M., Caputo, D., Caricato, A. P., Catalano, R., Chilà, D., Cirrone, G. A. P., Croci, T., Cuttone, G., De Cesare, G., Dunand, S., Fabi, M., Frontini, L., Grimani, C., Ionica, M., Kanxheri, K., Large, M., Liberali, V., Lovecchio, N., Martino, M., Maruccio, G., Mazza, G., Monteduro, A. G., Morozzi, A., Moscatelli, F., Nascetti, A., Pallotta, S., Papi, A., Passeri, D., Pedio, M., Petasecca, M., Petringa, G., Peverini, F., Piccolo, L., Placidi, P., Quarta, G., Rizzato, S., Rossi, G., Sabbatini, F., Servoli, L., Stabile, A., Talamonti, C., Thomet, J. E., Tosti, L., Villani, M., Wheadon, R. J., Wyrsch, N., and Zema, N.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

Hydrogenated amorphous silicon (a-Si:H) is a material having an intrinsically high radiation hardness that can be deposited on flexible substrates like Polyimide. For these properties a-Si:H can be used for the production of flexible sensors. a-Si:H sensors can be successfully utilized in dosimetry, beam monitoring for particle physics (x-ray, electron, gamma-ray and proton detection) and radiotherapy, radiation flux measurement for space applications (study of solar energetic particles and stellar events) and neutron flux measurements. In this paper we have studied the dosimetric x-ray response of n-i-p diodes deposited on Polyimide. We measured the linearity of the photocurrent response to x-rays versus dose-rate from which we have extracted the dosimetric x-ray sensitivity at various bias voltages. In particular low bias voltage operation has been studied to assess the high energy efficiency of these kind of sensor. A measurement of stability of x-ray response versus time has been shown. The effect of detectors annealing has been studied. Operation under bending at various bending radii is also shown.

Published
2023

3. Development of thin hydrogenated amorphous silicon detectors on a flexible substrate

Author

Menichelli, M., Bizzarri, M., Calcagnile, L., Caprai, M., Caricato, A. P., Catalano, R., Cirrone, G. A. P., Croci, T., Cuttone, G., Dunand, S., Fabi, M., Frontini, L., Gianfelici, B., Grimani, C., Ionica, M., Kanxheri, K., Large, M., Liberali, V., Martino, M., Maruccio, G., Mazza, G., Monteduro, A. G., Morozzi, A., Moscatelli, F., Pallotta, S., Papi, A., Passeri, D., Pedio, M., Petasecca, M., Petringa, G., Peverini, F., Piccolo, L., Placidi, P., Quarta, G., Rizzato, S., Rossi, G., Sabbatini, F., Stabile, A., Servoli, L., Talamonti, C., Villani, M., Wheadon, R. J., and Wyrsch, N.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The HASPIDE (Hydrogenated Amorphous Silicon PIxels DEtectors) project aims at the development of thin hydrogenated amorphous silicon (a-Si:H) detectors on flexible substrates (mostly Polyimide) for beam monitoring, neutron detection and space applications. Since a-Si:H is a material with superior radiation hardness, the benefit for the above-mentioned applications can be appreciated mostly in radiation harsh environments. Furthermore, the possibility to deposit this material on flexible substrates like Polyimide (PI), polyethylene naphthalate (PEN) or polyethylene terephthalate (PET) facilitates the usage of these detectors in medical dosimetry, beam flux and beam profile measurements. Particularly interesting is its use when positioned directly on the flange of the vacuum-to-air separation interface in a beam line, as well as other applications where a thin self-standing radiation flux detector is envisaged. In this paper, the HASPIDE project will be described and some preliminary results on PI and glass substrates will be reported.

Published
2022

4. Progress in the development of a KITWPA for the DARTWARS project

Author

Borghesi, M., Barone, C., Capelli, S., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., Di Gioacchino, D., Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Granata, V., Greco, A., Guarcello, C., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mauro, C., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rettaroli, A., Rizzato, S., Vinante, A., and Zannoni, M.

Subjects
Quantum Physics, Condensed Matter - Superconductivity
Abstract

DARTWARS (Detector Array Readout with Traveling Wave AmplifieRS) is a three years project that aims to develop high-performing innovative Traveling Wave Parametric Amplifiers (TWPAs) for low temperature detectors and qubit readout (C-band). The practical development follows two different promising approaches, one based on the Josephson junctions (TWJPA) and the other one based on the kinetic inductance of a high-resistivity superconductor (KITWPA). This paper presents the advancements made by the DARTWARS collaboration to produce a first working prototype of a KITWPA., Comment: 3 pages, 4 figures. Proceeding of Pisa15th Meeting conference

Published
2022
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5. Ultra low noise readout with travelling wave parametric amplifiers: the DARTWARS project

Author

Rettaroli, A., Barone, C., Borghesi, M., Capelli, S., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., Di Gioacchino, D., Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Granata, V., Greco, A., Guarcello, C., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mauro, C., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rizzato, S., Vinante, A., and Zannoni, M.

Subjects
Quantum Physics
Abstract

The DARTWARS project has the goal of developing high-performing innovative travelling wave parametric amplifiers with high gain, large bandwidth, high saturation power, and nearly quantum-limited noise. The target frequency region for its applications is 5 - 10 GHz, with an expected noise temperature of about 600 mK. The development follows two different approaches, one based on Josephson junctions and one based on kinetic inductance of superconductors. This contribution mainly focuses on the Josephson travelling wave parametric amplifier, presenting its design, preliminary measurements and the test of homogeneity of arrays of Josephson junctions., Comment: 4 pages, 5 figures. Proceeding of Pisa15th Meeting conference. arXiv admin note: text overlap with arXiv:2111.03409

Published
2022
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6. Detector Array Readout with Traveling Wave Amplifiers

Author

Giachero, A., Barone, C., Borghesi, M., Carapella, G., Caricato, A. P., Carusotto, I., Chang, W., Cian, A., Di Gioacchino, D., Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giubertoni, D., Greco, A., Kutlu, C., Leo, A., Ligi, C., Maccarrone, G., Margesin, B., Maruccio, G., Matlashov, A., Mauro, C., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rizzato, S., Semertzidis, Y. K., Uchaikin, S., and Vinante, A.

Subjects
Condensed Matter - Superconductivity, Quantum Physics
Abstract

Noise at the quantum limit over a large bandwidth is a fundamental requirement for future applications operating at millikelvin temperatures, such as the neutrino mass measurement, the next-generation x-ray observatory, the CMB measurement, the dark matter and axion detection, and the rapid high-fidelity readout of superconducting qubits. The read out sensitivity of arrays of microcalorimeter detectors, resonant axion-detectors, and qubits, is currently limited by the noise temperature and bandwidth of the cryogenic amplifiers. The DARTWARS (Detector Array Readout with Traveling Wave AmplifieRS) project has the goal of developing high-performing innovative traveling wave parametric amplifiers (TWPAs) with a high gain, a high saturation power, and a quantum-limited or nearly quantum-limited noise. The practical development follows two different promising approaches, one based on the Josephson junctions and the other one based on the kinetic inductance of a high-resistivity superconductor. In this contribution we present the aims of the project, the adopted design solutions and preliminary results from simulations and measurements.

Published
2021
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7. Testing of planar hydrogenated amorphous silicon sensors with charge selective contacts for the construction of 3D- detectors

Author

Menichelli, M., Bizzarri, M., Boscardin, M., Caprai, M., Caricato, A. P., Cirrone, G. A. P., Crivellari, M., Cupparo, I., Cuttone, G., Dunand, S., Fanò, L., Hammad, O., Ionica, M., Kanxheri, K., Large, M., Maruccio, G., Monteduro, A. G., Morozzi, A., Moscatelli, F., Papi, A., Passeri, D., Petasecca, M., Petringa, G., Quarta, G., Rizzato, S., Rossi, A., Rossi, G., Scorzoni, A., Servoli, L., Talamonti, C., Verzellesi, G., and Wyrsch, N.

Subjects
Physics - Instrumentation and Detectors
Abstract

Hydrogenated Amorphous Silicon (a-Si:H) is a material well known for its intrinsic radiation hardness and is primarily utilized in solar cells as well as for particle detection and dosimetry. Planar p-i-n diode detectors are fabricated entirely by means of intrinsic and doped PECVD of a mixture of Silane (SiH4) and molecular Hydrogen. In order to develop 3D detector geometries using a-Si:H, two options for the junction fabrication have been considered: ion implantation and charge selective contacts through atomic layer deposition. In order to test the functionality of the charge selective contact electrodes, planar detectors have been fabricated utilizing this technique. In this paper, we provide a general overview of the 3D fabrication project followed by the results of leakage current measurements and x-ray dosimetric tests performed on planar diodes containing charge selective contacts to investigate the feasibility of the charge selective contact methodology for integration with the proposed 3D detector architectures., Comment: Submitted to JINST

Published
2021
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8. Bimodal Approach for Noise Figures of Merit Evaluation in Quantum-Limited Josephson Traveling Wave Parametric Amplifiers

Author

Fasolo, L., Barone, C., Borghesi, M., Carapella, G., Caricato, A. P., Carusotto, I., Chung, W., Cian, A., Di Gioacchino, D., Enrico, E., Falferi, P., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Greco, A., Kutlu, C., Leo, A., Ligi, C., Livreri, P., Maccarrone, G., Margesin, B., Maruccio, G., Matlashov, A., Mauro, C., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rettaroli, A., Rizzato, S., Semertzidis, Y. K., Uchaikin, U., and Vinante, A.

Subjects
Condensed Matter - Superconductivity
Abstract

The advent of ultra-low noise microwave amplifiers revolutionized several research fields demanding quantum-limited technologies. Exploiting a theoretical bimodal description of a linear phase-preserving amplifier, in this contribution we analyze some of the intrinsic properties of a model architecture (i.e., an rf-SQUID based Josephson Traveling Wave Parametric Amplifier) in terms of amplification and noise generation for key case study input states (Fock and coherents). Furthermore, we present an analysis of the output signals generated by the parametric amplification mechanism when thermal noise fluctuations feed the device., Comment: 5 pages, 6 figures

Published
2021
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9. Neutron irradiation of Hydrogenated Amorphous Silicon p-i-n diodes and charge selective contacts detectors

Author

Menichelli, M., Bizzarri, M., Boscardin, M., Calcagnile, L., Caprai, M., Caricato, A.P., Cirrone, G.A.P., Crivellari, M., Cupparo, I., Cuttone, G., Dunand, S., Fanò, L., Gianfelici, B., Hammad, O., Ionica, M., Kanxheri, K., Large, M., Maruccio, G., Monteduro, A.G., Moscatelli, F., Morozzi, A., Papi, A., Passeri, D., Pedio, M., Petasecca, M., Petringa, G., Peverini, F., Quarta, G., Rizzato, S., Rossi, A., Rossi, G., Scorzoni, A., Servoli, L., Talamonti, C., Verzellesi, G., and Wyrsch, N.

Published
2023
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10. Detector Array Readout with Traveling Wave Amplifiers

Author

Giachero, A., Barone, C., Borghesi, M., Carapella, G., Caricato, A. P., Carusotto, I., Chang, W., Cian, A., Gioacchino, D. Di, Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giubertoni, D., Greco, A., Kutlu, C., Leo, A., Ligi, C., Maccarrone, G., Margesin, B., Maruccio, G., Matlashov, A., Mauro, C., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rizzato, S., Semertzidis, Y. K., Uchaikin, S., and Vinante, A.

Published
2022
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11. Development of KI-TWPAs for the DARTWARS project

Author

Ahrens, F, Ferri, E, Avallone, G, Barone, C, Borghesi, M, Callegaro, L, Carapella, G, Caricato, A, Carusotto, I, Cian, A, D'Elia, A, Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Granata, V, Guarcello, C, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mezzena, R, Monteduro, A, Moretti, R, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Piedjou, A, Piersanti, L, Rettaroli, A, Rizzato, S, Tocci, S, Vinante, A, Zannoni, M, Ahrens F., Ferri E., Avallone G., Barone C., Borghesi M., Callegaro L., Carapella G., Caricato A. P., Carusotto I., Cian A., D'Elia A., Gioacchino D. D., Enrico E., Falferi P., Fasolo L., Faverzani M., Filatrella G., Gatti C., Giachero A., Giubertoni D., Granata V., Guarcello C., Labranca D., Leo A., Ligi C., Maccarrone G., Mantegazzini F., Margesin B., Maruccio G., Mezzena R., Monteduro A. G., Moretti R., Nucciotti A., Oberto L., Origo L., Pagano S., Piedjou A. S., Piersanti L., Rettaroli A., Rizzato S., Tocci S., Vinante A., Zannoni M., Ahrens, F, Ferri, E, Avallone, G, Barone, C, Borghesi, M, Callegaro, L, Carapella, G, Caricato, A, Carusotto, I, Cian, A, D'Elia, A, Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Granata, V, Guarcello, C, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mezzena, R, Monteduro, A, Moretti, R, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Piedjou, A, Piersanti, L, Rettaroli, A, Rizzato, S, Tocci, S, Vinante, A, Zannoni, M, Ahrens F., Ferri E., Avallone G., Barone C., Borghesi M., Callegaro L., Carapella G., Caricato A. P., Carusotto I., Cian A., D'Elia A., Gioacchino D. D., Enrico E., Falferi P., Fasolo L., Faverzani M., Filatrella G., Gatti C., Giachero A., Giubertoni D., Granata V., Guarcello C., Labranca D., Leo A., Ligi C., Maccarrone G., Mantegazzini F., Margesin B., Maruccio G., Mezzena R., Monteduro A. G., Moretti R., Nucciotti A., Oberto L., Origo L., Pagano S., Piedjou A. S., Piersanti L., Rettaroli A., Rizzato S., Tocci S., Vinante A., and Zannoni M.

Abstract

Noise at the quantum limit over a broad bandwidth is a fundamental requirement for future cryogenic experiments for neutrino mass measurements, dark matter searches and Cosmic Microwave Background (CMB) measurements as well as for fast high-fidelity read-out of superconducting qubits. In the last years, Josephson Parametric Amplifiers (JPA) have demonstrated noise levels close to the quantum limit, but due to their narrow bandwidth, only few detectors or qubits per line can be read out in parallel. An alternative and innovative solution is based on superconducting parametric amplification exploiting the travelling-wave concept. Within the DARTWARS (Detector Array Readout with Travelling Wave AmplifieRS) project, we develop Kinetic Inductance Travelling-Wave Parametric Amplifiers (KI-TWPAs) for low temperature detectors and qubit read-out. KI-TWPAs are typically operated in a threewave mixing (3WM) mode and are characterised by a high gain, a high saturation power, a large amplification bandwidth and nearly quantum limited noise performance. The goal of the DARTWARS project is to optimise the KI-TWPA design, explore new materials, and investigate alternative fabrication processes in order to enhance the overall performance of the amplifier. In this contribution we present the advancements made by the DARTWARS collaboration to produce a working prototype of a KI-TWPA, from the fabrication to the characterisation.

Published
2024

12. Experimental Characterization of RF-SQUIDs Based Josephson Traveling Wave Parametric Amplifier Exploiting Resonant Phase Matching Scheme

Author

Fasolo, L, Ahrens, F, Avallone, G, Barone, C, Borghesi, M, Callegaro, L, Carapella, G, Caricato, A, Carusotto, I, Cian, A, D'Elia, A, Gioacchino, D, Falferi, P, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giubertoni, D, Granata, V, Guarcello, C, Labranca, D, Leo, A, Ligi, C, Livreri, P, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mezzena, R, Monteduro, A, Moretti, R, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Piedjou, A, Piersanti, L, Rettaroli, A, Rizzato, S, Tocci, S, Vinante, A, Zannoni, M, Giachero, A, Enrico, E, Fasolo, L., Ahrens, F., Avallone, G., Barone, C., Borghesi, M., Callegaro, L., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., D'Elia, A., Gioacchino, D. Di, Falferi, P., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giubertoni, D., Granata, V., Guarcello, C., Labranca, D., Leo, A., Ligi, C., Livreri, P., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mezzena, R., Monteduro, A. G., Moretti, R., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Piedjou, A. S., Piersanti, L., Rettaroli, A., Rizzato, S., Tocci, S., Vinante, A., Zannoni, M., Giachero, A., Enrico, E., Fasolo, L, Ahrens, F, Avallone, G, Barone, C, Borghesi, M, Callegaro, L, Carapella, G, Caricato, A, Carusotto, I, Cian, A, D'Elia, A, Gioacchino, D, Falferi, P, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giubertoni, D, Granata, V, Guarcello, C, Labranca, D, Leo, A, Ligi, C, Livreri, P, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mezzena, R, Monteduro, A, Moretti, R, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Piedjou, A, Piersanti, L, Rettaroli, A, Rizzato, S, Tocci, S, Vinante, A, Zannoni, M, Giachero, A, Enrico, E, Fasolo, L., Ahrens, F., Avallone, G., Barone, C., Borghesi, M., Callegaro, L., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., D'Elia, A., Gioacchino, D. Di, Falferi, P., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giubertoni, D., Granata, V., Guarcello, C., Labranca, D., Leo, A., Ligi, C., Livreri, P., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mezzena, R., Monteduro, A. G., Moretti, R., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Piedjou, A. S., Piersanti, L., Rettaroli, A., Rizzato, S., Tocci, S., Vinante, A., Zannoni, M., Giachero, A., and Enrico, E.

Abstract

This study presents recent advancements in Josephson Traveling Wave Parametric Amplifiers (JTWPAs) developed and tested at INRiM within the DARTWARS project framework. Combining Josephson junctions with superconducting coplanar waveguides, JTWPAs offer advanced capabilities for quantum-limited broadband microwave amplification and the emission of non-classical microwave radiation. The work delves into the architecture, optimization, and experimental characterization of a JTWPA with a Resonant Phase-Matching mechanism, highlighting signal gains and idler conversion factors in relation to pump power and signal frequency.

Published
2024

13. Broadband Parametric Amplification in DARTWARS

Author

Faverzani, M, Campana, P, Carobene, R, Gobbo, M, Ahrens, F, Avallone, G, Barone, C, Borghesi, M, Capelli, S, Carapella, G, Caricato, A, Callegaro, L, Carusotto, I, Celotto, A, Cian, A, D’Elia, A, Di Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Ferri, E, Filatrella, G, Gatti, C, Giubertoni, D, Granata, V, Guarcello, C, Irace, A, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mezzena, R, Monteduro, A, Moretti, R, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Piedjou Komnang, A, Piersanti, L, Rettaroli, A, Rizzato, S, Tocci, S, Vinante, A, Zannoni, M, Giachero, A, Faverzani, M., Campana, P., Carobene, R., Gobbo, M., Ahrens, F., Avallone, G., Barone, C., Borghesi, M., Capelli, S., Carapella, G., Caricato, A. P., Callegaro, L., Carusotto, I., Celotto, A., Cian, A., D’Elia, A., Di Gioacchino, D., Enrico, E., Falferi, P., Fasolo, L., Ferri, E., Filatrella, G., Gatti, C., Giubertoni, D., Granata, V., Guarcello, C., Irace, A., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mezzena, R., Monteduro, A. G., Moretti, R., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Piedjou Komnang, A. S., Piersanti, L., Rettaroli, A., Rizzato, S., Tocci, S., Vinante, A., Zannoni, M., Giachero, A., Faverzani, M, Campana, P, Carobene, R, Gobbo, M, Ahrens, F, Avallone, G, Barone, C, Borghesi, M, Capelli, S, Carapella, G, Caricato, A, Callegaro, L, Carusotto, I, Celotto, A, Cian, A, D’Elia, A, Di Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Ferri, E, Filatrella, G, Gatti, C, Giubertoni, D, Granata, V, Guarcello, C, Irace, A, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mezzena, R, Monteduro, A, Moretti, R, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Piedjou Komnang, A, Piersanti, L, Rettaroli, A, Rizzato, S, Tocci, S, Vinante, A, Zannoni, M, Giachero, A, Faverzani, M., Campana, P., Carobene, R., Gobbo, M., Ahrens, F., Avallone, G., Barone, C., Borghesi, M., Capelli, S., Carapella, G., Caricato, A. P., Callegaro, L., Carusotto, I., Celotto, A., Cian, A., D’Elia, A., Di Gioacchino, D., Enrico, E., Falferi, P., Fasolo, L., Ferri, E., Filatrella, G., Gatti, C., Giubertoni, D., Granata, V., Guarcello, C., Irace, A., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mezzena, R., Monteduro, A. G., Moretti, R., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Piedjou Komnang, A. S., Piersanti, L., Rettaroli, A., Rizzato, S., Tocci, S., Vinante, A., Zannoni, M., and Giachero, A.

Abstract

Superconducting parametric amplifiers offer the capability to amplify feeble signals with extremely low levels of added noise, potentially reaching quantum-limited amplification. This characteristic makes them essential components in the realm of high-fidelity quantum computing and serves to propel advancements in the field of quantum sensing. In particular, Traveling-Wave Parametric Amplifiers (TWPAs) may be especially suitable for practical applications due to their multi-Gigahertz amplification bandwidth, a feature lacking in Josephson Parametric Amplifiers (JPAs), despite the latter being a more established technology. This paper presents recent developments of the DARTWARS (Detector Array Readout with Traveling Wave AmplifieRS) project, focusing on the latest prototypes of Kinetic Inductance TWPAs (KITWPAs). The project aims to develop a KITWPA capable of achieving 20 dB of amplification. To enhance the production yield, the first prototypes were fabricated with half the length and expected gain of the final device. In this paper, we present the results of the characterization of one of the half-length prototypes. The measurements revealed an average amplification of approximately 9 dB across a 2 GHz bandwidth for a KITWPA spanning 17 mm in length.

Published
2024

14. Progress in the development of a KITWPA for the DARTWARS project

Author

Borghesi, M., Barone, C., Capelli, S., Carapella, G., Caricato, A.P., Carusotto, I., Cian, A., Di Gioacchino, D., Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Granata, V., Greco, A., Guarcello, C., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mauro, C., Mezzena, R., Monteduro, A.G., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rettaroli, A., Rizzato, S., Vinante, A., and Zannoni, M.

Published
2023
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15. Ultra low noise readout with traveling wave parametric amplifiers: The DARTWARS project

Author

Rettaroli, A., Barone, C., Borghesi, M., Capelli, S., Carapella, G., Caricato, A.P., Carusotto, I., Cian, A., Di Gioacchino, D., Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Granata, V., Greco, A., Guarcello, C., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mauro, C., Mezzena, R., Monteduro, A.G., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rizzato, S., Vinante, A., and Zannoni, M.

Published
2023
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17. HASPIDE: a project for the development of hydrogenated amorphous silicon radiation sensors on a flexible substrate

Author

Tosti, L., primary, Antognini, L., additional, Aziz, S., additional, Bashiri, A., additional, Calcagnile, L., additional, Caputo, D., additional, Caricato, A.P., additional, Catalano, R., additional, De Cesare, G., additional, Chilà, D., additional, Cirrone, G.A.P., additional, Croci, T., additional, Cuttone, G., additional, Dunand, S., additional, Fabi, M., additional, Frontini, L., additional, Grimani, C., additional, Ionica, M., additional, Kanxheri, K., additional, Large, M., additional, Liberali, V., additional, Lovecchio, N., additional, Martino, M., additional, Maruccio, G., additional, Mazza, G., additional, Menichelli, M., additional, Monteduro, A.G., additional, Morozzi, A., additional, Moscatelli, F., additional, Nascetti, A., additional, Pallotta, S., additional, Passeri, D., additional, Pedio, M., additional, Petasecca, M., additional, Petringa, G., additional, Peverini, F., additional, Piccolo, L., additional, Placidi, P., additional, Quarta, G., additional, Rizzato, S., additional, Sabbatini, F., additional, Servoli, L., additional, Stabile, A., additional, Talamonti, C., additional, Thomet, J.E., additional, Villani, M., additional, Wheadon, R.J., additional, Wyrsch, N., additional, and Zema, N., additional

Published
2024
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18. Nonlinear Behavior of Josephson Traveling Wave Parametric Amplifiers

Author

Guarcello, C, Ahrens, F, Avallone, G, Barone, C, Borghesi, M, Callegaro, L, Carapella, G, Caricato, A, Carusotto, I, Cian, A, D'Elia, A, Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Granata, V, Leo, A, Labranca, D, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mezzena, R, Monteduro, A, Moretti, R, Nucciotti, A, Oberto, L, Origo, L, Komnang, A, Pagano, S, Piersanti, L, Rettaroli, A, Rizzato, S, Tocci, S, Vinante, A, Zannoni, M, Guarcello, Claudio, Ahrens, Felix, Avallone, Guerino, Barone, Carlo, Borghesi, Matteo, Callegaro, Luca, Carapella, Giovanni, Caricato, Anna Paola, Carusotto, Iacopo, Cian, Alessandro, D'Elia, Alessandro, Gioacchino, Daniele Di, Enrico, Emanuele, Falferi, Paolo, Fasolo, Luca, Faverzani, Marco, Ferri, Elena, Filatrella, Giovanni, Gatti, Claudio, Giachero, Andrea, Giubertoni, Damiano, Granata, Veronica, Leo, Angelo, Labranca, Danilo, Ligi, Carlo, Maccarrone, Giovanni, Mantegazzini, Federica, Margesin, Benno, Maruccio, Giuseppe, Mezzena, Renato, Monteduro, Anna Grazia, Moretti, Roberto, Nucciotti, Angelo, Oberto, Luca, Origo, Luca, Komnang, Alex Stephane Piedjou, Pagano, Sergio, Piersanti, Luca, Rettaroli, Alessio, Rizzato, Silvia, Tocci, Simone, Vinante, Andrea, Zannoni, Mario, Guarcello, C, Ahrens, F, Avallone, G, Barone, C, Borghesi, M, Callegaro, L, Carapella, G, Caricato, A, Carusotto, I, Cian, A, D'Elia, A, Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Granata, V, Leo, A, Labranca, D, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mezzena, R, Monteduro, A, Moretti, R, Nucciotti, A, Oberto, L, Origo, L, Komnang, A, Pagano, S, Piersanti, L, Rettaroli, A, Rizzato, S, Tocci, S, Vinante, A, Zannoni, M, Guarcello, Claudio, Ahrens, Felix, Avallone, Guerino, Barone, Carlo, Borghesi, Matteo, Callegaro, Luca, Carapella, Giovanni, Caricato, Anna Paola, Carusotto, Iacopo, Cian, Alessandro, D'Elia, Alessandro, Gioacchino, Daniele Di, Enrico, Emanuele, Falferi, Paolo, Fasolo, Luca, Faverzani, Marco, Ferri, Elena, Filatrella, Giovanni, Gatti, Claudio, Giachero, Andrea, Giubertoni, Damiano, Granata, Veronica, Leo, Angelo, Labranca, Danilo, Ligi, Carlo, Maccarrone, Giovanni, Mantegazzini, Federica, Margesin, Benno, Maruccio, Giuseppe, Mezzena, Renato, Monteduro, Anna Grazia, Moretti, Roberto, Nucciotti, Angelo, Oberto, Luca, Origo, Luca, Komnang, Alex Stephane Piedjou, Pagano, Sergio, Piersanti, Luca, Rettaroli, Alessio, Rizzato, Silvia, Tocci, Simone, Vinante, Andrea, and Zannoni, Mario

Abstract

Recent advancements in quantum technologies and advanced detection experiments have underscored the pressing need for the detection of exceedingly weak signals within the microwave frequency spectrum. Addressing this challenge, the Josephson Traveling Wave Parametric Amplifier (JTWPA) has been proposed as a cryogenic front-end amplifier capable of approaching the quantum noise limit while providing a relevant bandwidth. This research is centered on a comprehensive numerical investigation of the JTWPA, without resorting to simplifications regarding the nonlinearity of the essential components. Specifically, this study focuses on a thorough examination of the system, characterized by coupled nonlinear differential equations representing all components of the device. Proper input and output signals at the device's boundaries are considered. The analysis of the output signals undergoing the parametric amplification process involves a detailed exploration of phase-space dynamics and Fourier spectral analysis of the output voltage. This study is conducted while considering the parameters ruling the response of the device under pump and signal excitations. In addition to the expected signal amplification, the findings reveal that the nonlinear nature of the system can give rise to unforeseen phenomena, depending on the system's operational conditions, which include: the generation of pump tone harmonics, modulation of the signal gain, and incommensurate frequency generation—effects that are not easily accommodated by simplistic linearized approaches. IEEE

Published
2024

19. Progress in the development of a KITWPA for the DARTWARS project

Author

Borghesi, M, Barone, C, Capelli, S, Carapella, G, Caricato, A, Carusotto, I, Cian, A, Di Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Granata, V, Greco, A, Guarcello, C, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rettaroli, A, Rizzato, S, Vinante, A, Zannoni, M, Borghesi M., Barone C., Capelli S., Carapella G., Caricato A. P., Carusotto I., Cian A., Di Gioacchino D., Enrico E., Falferi P., Fasolo L., Faverzani M., Ferri E., Filatrella G., Gatti C., Giachero A., Giubertoni D., Granata V., Greco A., Guarcello C., Labranca D., Leo A., Ligi C., Maccarrone G., Mantegazzini F., Margesin B., Maruccio G., Mauro C., Mezzena R., Monteduro A. G., Nucciotti A., Oberto L., Origo L., Pagano S., Pierro V., Piersanti L., Rajteri M., Rettaroli A., Rizzato S., Vinante A., Zannoni M., Borghesi, M, Barone, C, Capelli, S, Carapella, G, Caricato, A, Carusotto, I, Cian, A, Di Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Granata, V, Greco, A, Guarcello, C, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rettaroli, A, Rizzato, S, Vinante, A, Zannoni, M, Borghesi M., Barone C., Capelli S., Carapella G., Caricato A. P., Carusotto I., Cian A., Di Gioacchino D., Enrico E., Falferi P., Fasolo L., Faverzani M., Ferri E., Filatrella G., Gatti C., Giachero A., Giubertoni D., Granata V., Greco A., Guarcello C., Labranca D., Leo A., Ligi C., Maccarrone G., Mantegazzini F., Margesin B., Maruccio G., Mauro C., Mezzena R., Monteduro A. G., Nucciotti A., Oberto L., Origo L., Pagano S., Pierro V., Piersanti L., Rajteri M., Rettaroli A., Rizzato S., Vinante A., and Zannoni M.

Abstract

DARTWARS (Detector Array Readout with Traveling Wave AmplifieRS) is a three years project that aims to develop high-performing innovative Traveling Wave Parametric Amplifiers (TWPAs) for low temperature detectors and qubit readout (C-band). The practical development follows two different promising approaches, one based on the Josephson junctions (TWJPA) and the other one based on the kinetic inductance of a high-resistivity superconductor (KITWPA). This paper presents the advancements made by the DARTWARS collaboration to produce a first working prototype of a KITWPA.

Published
2023

20. Ultra low noise readout with traveling wave parametric amplifiers: The DARTWARS project

Author

Rettaroli, A, Barone, C, Borghesi, M, Capelli, S, Carapella, G, Caricato, A, Carusotto, I, Cian, A, Di Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Granata, V, Greco, A, Guarcello, C, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rizzato, S, Vinante, A, Zannoni, M, Rettaroli A., Barone C., Borghesi M., Capelli S., Carapella G., Caricato A. P., Carusotto I., Cian A., Di Gioacchino D., Enrico E., Falferi P., Fasolo L., Faverzani M., Ferri E., Filatrella G., Gatti C., Giachero A., Giubertoni D., Granata V., Greco A., Guarcello C., Labranca D., Leo A., Ligi C., Maccarrone G., Mantegazzini F., Margesin B., Maruccio G., Mauro C., Mezzena R., Monteduro A. G., Nucciotti A., Oberto L., Origo L., Pagano S., Pierro V., Piersanti L., Rajteri M., Rizzato S., Vinante A., Zannoni M., Rettaroli, A, Barone, C, Borghesi, M, Capelli, S, Carapella, G, Caricato, A, Carusotto, I, Cian, A, Di Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Granata, V, Greco, A, Guarcello, C, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rizzato, S, Vinante, A, Zannoni, M, Rettaroli A., Barone C., Borghesi M., Capelli S., Carapella G., Caricato A. P., Carusotto I., Cian A., Di Gioacchino D., Enrico E., Falferi P., Fasolo L., Faverzani M., Ferri E., Filatrella G., Gatti C., Giachero A., Giubertoni D., Granata V., Greco A., Guarcello C., Labranca D., Leo A., Ligi C., Maccarrone G., Mantegazzini F., Margesin B., Maruccio G., Mauro C., Mezzena R., Monteduro A. G., Nucciotti A., Oberto L., Origo L., Pagano S., Pierro V., Piersanti L., Rajteri M., Rizzato S., Vinante A., and Zannoni M.

Abstract

The DARTWARS project has the goal of developing high-performing innovative traveling wave parametric amplifiers with high gain, large bandwidth, high saturation power, and nearly quantum-limited noise. The target frequency region for its applications is 5–10 GHz, where the expected noise temperature is below 600 mK. The development follows two different approaches, one based on Josephson junctions and one based on kinetic inductance of superconductors. This contribution mainly focuses on the Josephson traveling wave parametric amplifier, presenting its design, preliminary measurements and the test of homogeneity of arrays of Josephson junctions.

Published
2023

21. Modeling of Josephson Traveling Wave Parametric Amplifiers

Author

Guarcello, C, Avallone, G, Barone, C, Borghesi, M, Capelli, S, Carapella, G, Caricato, A, Carusotto, I, Cian, A, Di Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Granata, V, Greco, A, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rettaroli, A, Rizzato, S, Vinante, A, Zannoni, M, Guarcello, C., Avallone, G., Barone, C., Borghesi, M., Capelli, S., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., Di Gioacchino, D., Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Granata, V., Greco, A., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mauro, C., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rettaroli, A., Rizzato, S., Vinante, A., Zannoni, M., Guarcello, C, Avallone, G, Barone, C, Borghesi, M, Capelli, S, Carapella, G, Caricato, A, Carusotto, I, Cian, A, Di Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Granata, V, Greco, A, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rettaroli, A, Rizzato, S, Vinante, A, Zannoni, M, Guarcello, C., Avallone, G., Barone, C., Borghesi, M., Capelli, S., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., Di Gioacchino, D., Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Granata, V., Greco, A., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mauro, C., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rettaroli, A., Rizzato, S., Vinante, A., and Zannoni, M.

Abstract

The recent developments in quantum technologies, as well as advanced detection experiments, have raised the need to detect extremely weak signals in the microwave frequency spectrum. To this aim, the Josephson travelling wave parametric amplifier, a device capable of reaching the quantum noise limit while providing a wide bandwidth, has been proposed as a suitable cryogenic front-end amplifier. This work deals with the numerical study of a Josephson travelling wave parametric amplifier, without approximations regarding the nonlinearity of the key elements. In particular, we focus on the investigation of the system of coupled nonlinear differential equations representing all the cells of the Josephson travelling wave parametric amplifier, with proper input and output signals at the boundaries. The investigation of the output signals generated by the parametric amplification process explores the phase-space and the Fourier spectral analysis of the output voltage, as a function of the parameters describing the pump and signal tones that excite the device. Beside the expected behavior, i.e., the signal amplification, we show that, depending on the system operation, unwanted effects (such as pump tone harmonics, incommensurate frequency generation, and noise rise), which are not accounted for in simple linearized approaches, can be generated in the whole nonlinear system. IEEE

Published
2023

22. Characterization of Traveling-Wave Josephson Parametric Amplifiers at T = 0.3 K

Author

Granata, V, Avallone, G, Barone, C, Borghesi, M, Capelli, S, Carapella, G, Caricato, A, Carusotto, I, Cian, A, Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Greco, A, Guarcello, C, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rettaroli, A, Rizzato, S, Vinante, A, Zannoni, M, Granata, V., Avallone, G., Barone, C., Borghesi, M., Capelli, S., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., Gioacchino, D. Di, Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Greco, A., Guarcello, C., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mauro, C., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rettaroli, A., Rizzato, S., Vinante, A., Zannoni, M., Granata, V, Avallone, G, Barone, C, Borghesi, M, Capelli, S, Carapella, G, Caricato, A, Carusotto, I, Cian, A, Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Greco, A, Guarcello, C, Labranca, D, Leo, A, Ligi, C, Maccarrone, G, Mantegazzini, F, Margesin, B, Maruccio, G, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Origo, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rettaroli, A, Rizzato, S, Vinante, A, Zannoni, M, Granata, V., Avallone, G., Barone, C., Borghesi, M., Capelli, S., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., Gioacchino, D. Di, Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Greco, A., Guarcello, C., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mauro, C., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rettaroli, A., Rizzato, S., Vinante, A., and Zannoni, M.

Abstract

The growing interest in quantum technologies, from fundamental physics experiments to quantum computing, demands for extremely performing electronics only adding the minimum amount of noise admitted by quantum mechanics to the input signal (i.e. quantum-limited electronics). Superconducting microwave amplifiers, due to their dissipationless nature, exhibit outstanding performances in terms of noise (quantum limited), and gain. However, bandwidth and saturation power still show space for substantial improvement. Within the DARTWARS* collaboration, we are developing state-of-the-art microwave superconducting amplifiers based on Josephson junction arrays and on distributed kinetic inductance transmission lines. Here we report the realization of a setup for the characterization of the performances of Josephson Traveling-Wave Parametric Amplifiers (JTWPA) at a temperature of 300 mK. Although in the final experimental setup these amplifiers will operate at a base temperature of about 20 mK, their characterization at 300 mK allows to evidence the main aspects of their performances, but the ultimate noise level. This represents a quick and relatively inexpensive way to test these superconductive devices that can be of help to improve their design and fabrication. IEEE

Published
2023

23. CUTTING-EDGE A-SI:H DOSIMETER TO OPERATE IN VERY DEMANDING RADIOTHERAPY APPLICATIONS

Author

Talamonti, C., primary, Petasecca, M., additional, Pallotta, S., additional, Large, M., additional, Grimani, C., additional, Calcagnile, L., additional, Caricato, A.P., additional, Cirrone, G.A.P., additional, Croci, T., additional, Cuttone, G., additional, Dunand, S., additional, Fabi, M., additional, Frontini, L., additional, Ionica, M., additional, Kanxheri, K., additional, Liberali, V., additional, Martino, M., additional, Maruccio, G., additional, Mazza, G., additional, Menichelli, M., additional, Monteduro, A.G., additional, Morozzi, A., additional, Moscatelli, F., additional, Passeri, D., additional, Pedio, M., additional, Pedringa, G., additional, Peverini, F., additional, Piccolo, L., additional, Placidi, P., additional, Quarta, G., additional, Rizzato, S., additional, Sabbatini, F., additional, Stabile, A., additional, Wheadon, R.J., additional, Wyrsch, N., additional, Villani, M., additional, and Servoli, L., additional

Published
2023
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27. Detector Array Readout with Traveling Wave Amplifiers

Author

Giachero, A, Barone, C, Borghesi, M, Carapella, G, Caricato, A, Carusotto, I, Chang, W, Cian, A, Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giubertoni, D, Greco, A, Kutlu, C, Leo, A, Ligi, C, Maccarrone, G, Margesin, B, Maruccio, G, Matlashov, A, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rizzato, S, Semertzidis, Y, Uchaikin, S, Vinante, A, Giachero A., Barone C., Borghesi M., Carapella G., Caricato A. P., Carusotto I., Chang W., Cian A., Gioacchino D. D., Enrico E., Falferi P., Fasolo L., Faverzani M., Ferri E., Filatrella G., Gatti C., Giubertoni D., Greco A., Kutlu C., Leo A., Ligi C., Maccarrone G., Margesin B., Maruccio G., Matlashov A., Mauro C., Mezzena R., Monteduro A. G., Nucciotti A., Oberto L., Pagano S., Pierro V., Piersanti L., Rajteri M., Rizzato S., Semertzidis Y. K., Uchaikin S., Vinante A., Giachero, A, Barone, C, Borghesi, M, Carapella, G, Caricato, A, Carusotto, I, Chang, W, Cian, A, Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giubertoni, D, Greco, A, Kutlu, C, Leo, A, Ligi, C, Maccarrone, G, Margesin, B, Maruccio, G, Matlashov, A, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rizzato, S, Semertzidis, Y, Uchaikin, S, Vinante, A, Giachero A., Barone C., Borghesi M., Carapella G., Caricato A. P., Carusotto I., Chang W., Cian A., Gioacchino D. D., Enrico E., Falferi P., Fasolo L., Faverzani M., Ferri E., Filatrella G., Gatti C., Giubertoni D., Greco A., Kutlu C., Leo A., Ligi C., Maccarrone G., Margesin B., Maruccio G., Matlashov A., Mauro C., Mezzena R., Monteduro A. G., Nucciotti A., Oberto L., Pagano S., Pierro V., Piersanti L., Rajteri M., Rizzato S., Semertzidis Y. K., Uchaikin S., and Vinante A.

Abstract

Reducing noise to the quantum limit over a large bandwidth is a fundamental requirement for future applications operating at millikelvin temperatures, such as the neutrino mass measurement, the next-generation X-ray observatory, the CMB measurement, the dark matter and axion detection, and the rapid high-fidelity readout of superconducting qubits. The read out sensitivity of arrays of microcalorimeter detectors, resonant axion-detectors, and qubits, is currently limited by the noise temperature and bandwidth of the cryogenic amplifiers. The Detector Array Readout with Traveling Wave Amplifiers project has the goal of developing high-performing innovative traveling wave parametric amplifiers with a high gain, a high saturation power, and a quantum-limited or nearly quantum-limited noise. The practical development follows two different promising approaches, one based on the Josephson junctions and the other one based on the kinetic inductance of a high-resistivity superconductor. In this contribution, we present the aims of the project, the adopted design solutions and preliminary results from simulations and measurements.

Published
2022

28. Bimodal Approach for Noise Figures of Merit Evaluation in Quantum-Limited Josephson Traveling Wave Parametric Amplifiers

Author

Fasolo, L, Barone, C, Borghesi, M, Carapella, G, Caricato, A, Carusotto, I, Chung, W, Cian, A, Di Gioacchino, D, Enrico, E, Falferi, P, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Greco, A, Kutlu, C, Leo, A, Ligi, C, Livreri, P, Maccarone, G, Margesin, B, Maruccio, G, Matlashov, A, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rettaroli, A, Rizzato, S, Semertzidis, Y, Uchaikin, S, Vinante, A, Fasolo L., Barone C., Borghesi M., Carapella G., Caricato A. P., Carusotto I., Chung W., Cian A., Di Gioacchino D., Enrico E., Falferi P., Faverzani M., Ferri E., Filatrella G., Gatti C., Giachero A., Giubertoni D., Greco A., Kutlu C., Leo A., Ligi C., Livreri P., Maccarone G., Margesin B., Maruccio G., Matlashov A., Mauro C., Mezzena R., Monteduro A. G., Nucciotti A., Oberto L., Pagano S., Pierro V., Piersanti L., Rajteri M., Rettaroli A., Rizzato S., Semertzidis Y. K., Uchaikin S. V., Vinante A., Fasolo, L, Barone, C, Borghesi, M, Carapella, G, Caricato, A, Carusotto, I, Chung, W, Cian, A, Di Gioacchino, D, Enrico, E, Falferi, P, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Greco, A, Kutlu, C, Leo, A, Ligi, C, Livreri, P, Maccarone, G, Margesin, B, Maruccio, G, Matlashov, A, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Pagano, S, Pierro, V, Piersanti, L, Rajteri, M, Rettaroli, A, Rizzato, S, Semertzidis, Y, Uchaikin, S, Vinante, A, Fasolo L., Barone C., Borghesi M., Carapella G., Caricato A. P., Carusotto I., Chung W., Cian A., Di Gioacchino D., Enrico E., Falferi P., Faverzani M., Ferri E., Filatrella G., Gatti C., Giachero A., Giubertoni D., Greco A., Kutlu C., Leo A., Ligi C., Livreri P., Maccarone G., Margesin B., Maruccio G., Matlashov A., Mauro C., Mezzena R., Monteduro A. G., Nucciotti A., Oberto L., Pagano S., Pierro V., Piersanti L., Rajteri M., Rettaroli A., Rizzato S., Semertzidis Y. K., Uchaikin S. V., and Vinante A.

Abstract

The advent of ultra-low noise microwave amplifiers revolutionized several research fields demanding for quantum-limited technologies. Exploiting a theoretical bimodal description of a linear phase-preserving amplifier, in this contribution we analyze some of the intrinsic properties of a model architecture (i.e., an rf-SQUID based Josephson Traveling Wave Parametric Amplifier) in terms of amplification and noise generation for key case study input states (Fock and coherents). Furthermore, we present an analysis of the output signals generated by the parametric amplification mechanism when thermal noise fluctuations feed the device.

Published
2022

30. MO-04.13 - CUTTING-EDGE A-SI:H DOSIMETER TO OPERATE IN VERY DEMANDING RADIOTHERAPY APPLICATIONS

Author

Talamonti, C., Petasecca, M., Pallotta, S., Large, M., Grimani, C., Calcagnile, L., Caricato, A.P., Cirrone, G.A.P., Croci, T., Cuttone, G., Dunand, S., Fabi, M., Frontini, L., Ionica, M., Kanxheri, K., Liberali, V., Martino, M., Maruccio, G., Mazza, G., Menichelli, M., Monteduro, A.G., Morozzi, A., Moscatelli, F., Passeri, D., Pedio, M., Pedringa, G., Peverini, F., Piccolo, L., Placidi, P., Quarta, G., Rizzato, S., Sabbatini, F., Stabile, A., Wheadon, R.J., Wyrsch, N., Villani, M., and Servoli, L.

Published
2023
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31. Development of KI-TWPAs for the DARTWARS Project

Author

Ahrens, F., Ferri, E., Avallone, G., Barone, C., Borghesi, M., Callegaro, L., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., D'Elia, A., Gioacchino, D. Di, Enrico, E., Falferi, P., Fasolo, L., Faverzani, M., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Granata, V., Guarcello, C., Labranca, D., Leo, A., Ligi, C., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mezzena, R., Monteduro, A. G., Moretti, R., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Piedjou, A. S., Piersanti, L., Rettaroli, A., Rizzato, S., Tocci, S., Vinante, A., and Zannoni, M.

Abstract

Noise at the quantum limit over a broad bandwidth is a fundamental requirement for future cryogenic experiments for neutrino mass measurements, dark matter searches, and Cosmic Microwave Background (CMB) measurements as well as for fast high-fidelity read-out of superconducting qubits. In the last years, Josephson Parametric Amplifiers (JPA) have demonstrated noise levels close to the quantum limit, but due to their narrow bandwidth, only few detectors or qubits per line can be read out in parallel. An alternative and innovative solution is based on superconducting parametric amplification exploiting the travelling-wave concept. Within the Detector Array Readout with Travelling Wave AmplifieRS (DARTWARS) project, we develop Kinetic Inductance Travelling-Wave Parametric Amplifiers (KI-TWPAs) for low temperature detectors and qubit read-out. KI-TWPAs are typically operated in a three-wave mixing (3WM) mode and are characterised by a high gain, a high saturation power, a large amplification bandwidth, and nearly quantum limited noise performance. The goal of the DARTWARS project is to optimise the KI-TWPA design, explore new materials, and investigate alternative fabrication processes in order to enhance the overall performance of the amplifier. In this contribution we present the advancements made by the DARTWARS collaboration to produce a working prototype of a KI-TWPA, from the fabrication to the characterisation.

Published
2024
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32. Experimental Characterization of RF-SQUIDs Based Josephson Traveling Wave Parametric Amplifier Exploiting Resonant Phase Matching Scheme

Author

Fasolo, L., Ahrens, F., Avallone, G., Barone, C., Borghesi, M., Callegaro, L., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., D'Elia, A., Gioacchino, D. Di, Falferi, P., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giubertoni, D., Granata, V., Guarcello, C., Labranca, D., Leo, A., Ligi, C., Livreri, P., Maccarrone, G., Mantegazzini, F., Margesin, B., Maruccio, G., Mezzena, R., Monteduro, A. G., Moretti, R., Nucciotti, A., Oberto, L., Origo, L., Pagano, S., Piedjou, A. S., Piersanti, L., Rettaroli, A., Rizzato, S., Tocci, S., Vinante, A., Zannoni, M., Giachero, A., and Enrico, E.

Abstract

This study presents recent advancements in Josephson Traveling Wave Parametric Amplifiers (JTWPAs) developed and tested at Istituto Nazionale di Ricerca Metrologica within the Detector Array Readout with Traveling Wave AmplifieRS project framework. Combining Josephson junctions with superconducting coplanar waveguides, JTWPAs offer advanced capabilities for quantum-limited broadband microwave amplification and the emission of non-classical microwave radiation. The work delves into the architecture, optimization, and experimental characterization of a JTWPA with a Resonant Phase-Matching mechanism, highlighting signal gains and idler conversion factors in relation to pump power and signal frequency.

Published
2024
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33. X-ray qualification of hydrogenated amorphous silicon sensors on flexible substrate

Author

Menichelli, M., Antognini, L., Bashiri, A., Bizzarri, M., Calcagnile, L., Caprai, M., Caricato, A. P., Catalano, R., Cirrone, G. A. P., Croci, T., Cuttone, G., Dunand, S., Fabi, M., Frontini, L., Grimani, C., Ionica, M., Kanxheri, K., Large, M., Liberali, V., Martino, M., Maruccio, G., Mazza, G., Monteduro, A. G., Morozzi, A., Moscatelli, F., Pallotta, S., Papi, A., Passeri, D., Pedio, M., Petasecca, M., Petringa, G., Peverini, F., Piccolo, L., Placidi, P., Quarta, G., Rizzato, S., Rossi, G., Sabbatini, F., Stabile, A., Servoli, L., Talamonti, C., Tosti, L., Villani, M., Wheadon, R. J., Wyrsch, N., and Zema, N.

Subjects
Neutrons, Flexible detectors, Sensitivity, Polyethylene, Particle measurements, Sensitivity, Polyethylene, PIN photodiodes, Detectors, Polyimides, Neutrons, Particle measurements, Hydrogenated Silicon detectors, Radiation Hardness, Flexible detectors, Polyimides, Detectors, PIN photodiodes, Hydrogenated Silicon detectors, Radiation Hardness
Published
2023

34. Noise Figures of Merit of rf-SQUID-based Josephson Travelling Wave Parametric Amplifiers

Author

Fasolo, L., Barone, C., Borghesi, M., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., Di Gioacchino, D., Enrico, E., Falferi, P., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Greco, A., Leo, A., Ligi, C., Livreri, P., Maccarrone, G., Margesin, B., Maruccio, G., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rizzato, S., Vinante, A., Fasolo, L., Barone, C., Borghesi, M., Carapella, G., Caricato, A. P., Carusotto, I., Cian, A., Di Gioacchino, D., Enrico, E., Falferi, P., Faverzani, M., Ferri, E., Filatrella, G., Gatti, C., Giachero, A., Giubertoni, D., Greco, A., Leo, A., Ligi, C., Livreri, P., Maccarrone, G., Margesin, B., Maruccio, G., Mezzena, R., Monteduro, A. G., Nucciotti, A., Oberto, L., Pagano, S., Pierro, V., Piersanti, L., Rajteri, M., Rizzato, S., and Vinante, A.

Subjects
Noise Figure, Power Gain, Josephson Traveling Wave Parameter Amplifier, Settore ING-INF/01 - Elettronica
Abstract

The characterization of the rf-SQUID-based JTWPA in terms of its noise figure and gain for different input states (Fock states or Coherent states) has been carried out. The spectral distribution of the noise temperature Tn and gain G presents a region where the amplifier has a relatively high gain with a thermal noise that can go beyond the standard quantum limit =ℏ/2 (valid only for single mode input states [44]) as shown in Fig. 3. The TWJPA is here biased in its 3WM regime and pumped at p = 12 GHz.

Published
2021

35. Development of quantum limited superconducting amplifiers for advanced detection

Author

Pagano, S, Barone, C, Borghesi, M, Chung, W, Carapella, G, Caricato, A, Carusotto, I, Cian, A, Di Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Greco, A, Kutlu, C, Leo, A, Ligi, C, Maccarrone, G, Margesin, B, Maruccio, G, Matlashov, A, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Pierro, V, Piersanti, L, Rajteri, M, Rizzato, S, Semertzidis, Y, Uchaikin, S, Vinante, A, Pagano, Sergio, Barone, Carlo, Borghesi, Matteo, Chung, Woohyun, Carapella, Giovanni, Caricato, Anna Paola, Carusotto, Iacopo, Cian, Alessandro, Di Gioacchino, Daniele, Enrico, Emanuele, Falferi, Paolo, Fasolo, Luca, Faverzani, Marco, Ferri, Elena, Filatrella, Giovanni, Gatti, Claudio, Giachero, Andrea, Giubertoni, Damiano, Greco, Angelo, Kutlu, Caglar, Leo, Angelo, Ligi, C., Maccarrone, Giovanni, Margesin, Benno, Maruccio, Giuseppe, Matlashov, Andrei, Mauro, Costantino, Mezzena, Renato, Monteduro, Anna Grazia, Nucciotti, Angelo, Oberto, Luca, Pierro, Vincenzo, Piersanti, Luca, Rajteri, Mauro, Rizzato, Silvia, Semertzidis, Yannis K, Uchaikin, Sergey V., Vinante, Andrea, Pagano, S, Barone, C, Borghesi, M, Chung, W, Carapella, G, Caricato, A, Carusotto, I, Cian, A, Di Gioacchino, D, Enrico, E, Falferi, P, Fasolo, L, Faverzani, M, Ferri, E, Filatrella, G, Gatti, C, Giachero, A, Giubertoni, D, Greco, A, Kutlu, C, Leo, A, Ligi, C, Maccarrone, G, Margesin, B, Maruccio, G, Matlashov, A, Mauro, C, Mezzena, R, Monteduro, A, Nucciotti, A, Oberto, L, Pierro, V, Piersanti, L, Rajteri, M, Rizzato, S, Semertzidis, Y, Uchaikin, S, Vinante, A, Pagano, Sergio, Barone, Carlo, Borghesi, Matteo, Chung, Woohyun, Carapella, Giovanni, Caricato, Anna Paola, Carusotto, Iacopo, Cian, Alessandro, Di Gioacchino, Daniele, Enrico, Emanuele, Falferi, Paolo, Fasolo, Luca, Faverzani, Marco, Ferri, Elena, Filatrella, Giovanni, Gatti, Claudio, Giachero, Andrea, Giubertoni, Damiano, Greco, Angelo, Kutlu, Caglar, Leo, Angelo, Ligi, C., Maccarrone, Giovanni, Margesin, Benno, Maruccio, Giuseppe, Matlashov, Andrei, Mauro, Costantino, Mezzena, Renato, Monteduro, Anna Grazia, Nucciotti, Angelo, Oberto, Luca, Pierro, Vincenzo, Piersanti, Luca, Rajteri, Mauro, Rizzato, Silvia, Semertzidis, Yannis K, Uchaikin, Sergey V., and Vinante, Andrea

Abstract

Ultralow-noise microwave amplification and detection play a central role in different applications, going from fundamental physics experiments to the deployment of quantum technologies. In many applications the necessity of reading multiple detectors, or cavities or qubits, calls for large bandwidth amplifiers with the lowest possible noise. Current technologies are based on High Electron Mobility Transistors and Josephson Parametric Amplifiers. Both have limitations, the former in terms of the minimum noise, the latter in terms of bandwidth. Superconducting Traveling Wave Parametric Amplifiers (TWPAs) have the potential of offering quantum limited noise and large bandwidth. These amplifiers are based on the parametric amplification of microwaves traveling along a transmission line with embedded nonlinear elements. We are developing superconducting TWPAs based both on Josephson junction arrays (Traveling Wave Josephson Parametric mplifiers) and on nonlinear kinetic inductance (Dispersion Engineered Traveling Wave Kinetic Inductance Amplifiers). Our goal is to achieve large bandwidth (in the 5 to 10 GHz range), large gain (more than 20 dB), large saturation power (more than -50 dBm), and near quantum limited noise (noise temperature less than 600 mK). Current achievements in the design and development of the high performance TWPAs are here reported and discussed, together with current limitations and possible future developments.

Published
2022

36. Bimodal Approach for Noise Figures of Merit Evaluation in Quantum-Limited Josephson Traveling Wave Parametric Amplifiers

Author

Fasolo, L., primary, Barone, C., additional, Borghesi, M., additional, Carapella, G., additional, Caricato, A. P., additional, Carusotto, I., additional, Chung, W., additional, Cian, A., additional, Gioacchino, D. Di, additional, Enrico, E., additional, Falferi, P., additional, Faverzani, M., additional, Ferri, E., additional, Filatrella, G., additional, Gatti, C., additional, Giachero, A., additional, Giubertoni, D., additional, Greco, A., additional, Kutlu, C., additional, Leo, A., additional, Ligi, C., additional, Livreri, P., additional, Maccarrone, G., additional, Margesin, B., additional, Maruccio, G., additional, Matlashov, A., additional, Mauro, C., additional, Mezzena, R., additional, Monteduro, A. G., additional, Nucciotti, A., additional, Oberto, L., additional, Pagano, S., additional, Pierro, V., additional, Piersanti, L., additional, Rajteri, M., additional, Rettaroli, A., additional, Rizzato, S., additional, Semertzidis, Y. K., additional, Uchaikin, S., additional, and Vinante, A., additional

Published
2022
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37. Development of Quantum Limited Superconducting Amplifiers for Advanced Detection

Author

Pagano, S., primary, Barone, C., additional, Borghesi, M., additional, Chung, W., additional, Carapella, G., additional, Caricato, A. P., additional, Carusotto, I., additional, Cian, A., additional, Gioacchino, D. Di, additional, Enrico, E., additional, Falferi, P., additional, Fasolo, L., additional, Faverzani, M., additional, Ferri, E., additional, Filatrella, G., additional, Gatti, C., additional, Giachero, A., additional, Giubertoni, D., additional, Greco, A., additional, Kutlu, C., additional, Leo, A., additional, Ligi, C., additional, Maccarrone, G., additional, Margesin, B., additional, Maruccio, G., additional, Matlashov, A., additional, Mauro, C., additional, Mezzena, R., additional, Monteduro, A. G., additional, Nucciotti, A., additional, Oberto, L., additional, Pierro, V., additional, Piersanti, L., additional, Rajteri, M., additional, Rettaroli, A., additional, Rizzato, S., additional, Semertzidis, Y. K., additional, Uchaikin, S., additional, and Vinante, A., additional

Published
2022
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38. Testing of planar hydrogenated amorphous silicon sensors with charge selective contacts for the construction of 3D-detectors

Author

Menichelli, M., primary, Bizzarri, M., additional, Boscardin, M., additional, Caprai, M., additional, Caricato, A.P., additional, Cirrone, G.A.P., additional, Crivellari, M., additional, Cupparo, I., additional, Cuttone, G., additional, Dunand, S., additional, Fanò, L., additional, Hammad, O., additional, Ionica, M., additional, Kanxheri, K., additional, Large, M., additional, Maruccio, G., additional, Monteduro, A.G., additional, Morozzi, A., additional, Moscatelli, F., additional, Papi, A., additional, Passeri, D., additional, Petasecca, M., additional, Petringa, G., additional, Quarta, G., additional, Rizzato, S., additional, Rossi, A., additional, Rossi, G., additional, Scorzoni, A., additional, Servoli, L., additional, Talamonti, C., additional, Verzellesi, G., additional, and Wyrsch, N., additional

Published
2022
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40. 1207O Bevacizumab + erlotinib vs erlotinib alone as first-line treatment of pts with EGFR mutated advanced non squamous NSCLC: Final analysis of the multicenter, randomized, phase III BEVERLY trial

Author

Piccirillo, M.C., primary, Bonanno, L., additional, Garassino, M.C.C., additional, Dazzi, C., additional, Cavanna, L., additional, Esposito, G., additional, Burgio, M.A., additional, Rosetti, F., additional, Rizzato, S., additional, Arenare, L., additional, Gargiulo, P., additional, Di Liello, R., additional, De Marinis, F., additional, Crinò, L., additional, Morgillo, F., additional, Ciardiello, F., additional, Normanno, N., additional, Gallo, C., additional, Gridelli, C., additional, and Morabito, A., additional

Published
2021
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41. 1312P Prognostic impact of KRAS status in patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitor monotherapy

Author

Pelizzari, G., primary, Corvaja, C., additional, Targato, G., additional, Buriolla, S., additional, Bortolot, M., additional, Torresan, S., additional, Fantin, A., additional, De Maglio, G., additional, Rossetto, C., additional, Rizzato, S., additional, Fasola, G., additional, and Follador, A., additional

Published
2021
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42. [Zinc(II)(Pyridine-Containing Ligand)] Complexes as Single-Component Efficient Catalyst for Chemical Fixation of CO2 with Epoxides

Author

Cavalleri, M, Panza, N, di Biase, A, Tseberlidis, G, Rizzato, S, Abbiati, G, Caselli, A, Cavalleri, M, Panza, N, di Biase, A, Tseberlidis, G, Rizzato, S, Abbiati, G, and Caselli, A

Abstract

The reaction between epoxides and CO2 to yield cyclic carbonates is efficiently promoted under solvent-free and relatively mild reaction conditions (0.5 mol % catalyst loading, 0.8 MPa, 125 °C) by zinc(II) complexes of pyridine containing macrocyclic ligands (Pc−L pyridinophanes). The zinc complexes have been fully characterized, including X-ray structural determination. The [Zn(II)X(Pc−L)]X complexes showed good solubility in several polar solvents, including cyclic carbonates. The scope of the reaction under solvent-free conditions has been studied and good to quantitative conversions with excellent selectivities have been obtained, starting from terminal epoxides. When solvent-free conditions were not possible (solid epoxides or low solubility of the catalyst in the oxirane) the use of cyclic carbonates as solvents has been successfully investigated. The remarkable stability of the catalytic system has been demonstrated by a series of consecutive runs.

Published
2021

44. Catalytic Selective Oxidation of Primary and Secondary Alcohols Using Nonheme [Iron(III)(Pyridine-Containing Ligand)] Complexes

Author

Panza, N, di Biase, A, Rizzato, S, Gallo, E, Tseberlidis, G, Caselli, A, Panza, N, di Biase, A, Rizzato, S, Gallo, E, Tseberlidis, G, and Caselli, A

Abstract

The selective oxidation of different primary and secondary alcohols to carbonyl compounds by hydrogen peroxide was found to be catalyzed in conversion ranging from good to excellent by an iron(III) complex of a pyridine-containing macrocyclic ligand (Pc-L), without the need of any additive. The choice of the counteranion (Cl, Br, OTf) appeared to be of fundamental importance and the best results in terms of selectivity (up to 99 %) and conversion (up to 98 %) were obtained using the well-characterized [Fe(III)(Br)2(Pc-L)]Br complex, 4c. Magnetic moments in solid-state, also confirmed in solution ([D6]DMSO) by Evans NMR method, were calculated and point out to an iron metal center in the high spin state of 5/2. The crystal structure shows that the iron(III) center is coordinated by the four nitrogen atoms of the macrocycle and two bromide anions to form a distorted octahedral coordination environment. The catalytic oxidation of benzyl alcohol in acetonitrile was found occurring with better conversions and selectivities than in other solvents. The reaction proved to be quite general, tolerating aromatic and aliphatic alcohols, although very low yields were obtained for terminal aliphatic alcohols. Preliminary mechanistic studies are in agreement with a catalytic cycle promoted by a high-spin iron complex.

Published
2020

45. 369MO Final results of depatuxizumab mafodotin plus temozolomide in recurrent glioblastoma patients: Real-world experience from a multicenter study of Italian Association of Neuro-Oncology (AINO)

Author

Padovan, M., primary, Eoli, M., additional, Pellerino, A., additional, Rizzato, S., additional, Caserta, C., additional, Simonelli, M., additional, Michiara, M., additional, Caccese, M., additional, Anghileri, E., additional, Finocchiaro, G., additional, Zagonel, V., additional, Rudà, R., additional, and Lombardi, G., additional

Published
2020
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46. 361O Defining the prognostic role of MGMT methylation value by pyrosequencing assay in glioblastoma patients: A large Italian multicenter study

Author

Caccese, M., primary, Simonelli, M., additional, Bellu, L., additional, Villani, V., additional, Rizzato, S., additional, Ius, T., additional, Pasqualetti, F., additional, Russo, M., additional, Franchino, F., additional, Amoroso, R., additional, Bertorelle, R., additional, Cavallin, F., additional, Dipasquale, A., additional, Carosi, M., additional, Pizzolitto, S., additional, Cesselli, D., additional, Gardiman, M.P., additional, Padovan, M., additional, Zagonel, V., additional, and Lombardi, G., additional

Published
2020
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47. Phase stability and morphology of gel grown crystals: The case of cdcl2-bpp polymeric system

Author

Lo Presti, L, Moret, M, Rizzato, S, Lo Presti, L, Moret, M, and Rizzato, S

Abstract

A phenomenological study is carried out on a complex two-component diffusion-reacting system in gel, that is, the Cd-1,3-bis(4-pyridyl)propane (Cd-bpp) coordination polymer. The latter can exist in three solid forms, which exploit a 1:1 correspondence among the Cd/bpp ratio, the crystal structure and the crystal morphology (1/2: bipyramids; 2/3: needles; 1/3: plates). The aim was to clarify the role of key physicochemical variables (reactant concentrations, composition of the solvent and density of the transport medium) in determining the chemical nature and the morphology of the final crystallization products. The gel method was tested in a variety of different crystallization configurations, including single and double diffusion techniques. The density of the gel primarily affects the morphology of the synthesized crystals, with denser media favouring the needle-like 2/3 Cd-bpp species and diluted ones the 1/2 Cd-bpp bipyramidal one. However, higher densities of the gel are generally associated to strained crystals. The solvent composition is also important, as for example the 1/2 Cd-bpp bipyramids require at least a minimum amount of ethanol to appear. We demonstrated that in gel the strict “equality” stoichiometric criteria for metal-to-ligand ratios can be sometimes eluded, as non–equilibrium concentrations can be locally attained. In this respect, the crystallization geometry was proven to act as a key tool to influence the crystallization output, as it determines the direction and magnitude of the concentration gradients. Finally, the use of U tubes to perform one-pot screenings of a large part of the crystallization space is discussed.

Published
2019

48. Controlling Selectivity in Alkene Oxidation: Anion Driven Epoxidation or Dihydroxylation Catalysed by [Iron(III)(Pyridine-Containing Ligand)] Complexes

Author

Tseberlidis, G, Demonti, L, Pirovano, V, Scavini, M, Cappelli, S, Rizzato, S, Vicente, R, Caselli, A, Tseberlidis, Giorgio, Demonti, Luca, Pirovano, Valentina, Scavini, Marco, Cappelli, Serena, Rizzato, Silvia, Vicente, Rubén, Caselli, Alessandro, Tseberlidis, G, Demonti, L, Pirovano, V, Scavini, M, Cappelli, S, Rizzato, S, Vicente, R, Caselli, A, Tseberlidis, Giorgio, Demonti, Luca, Pirovano, Valentina, Scavini, Marco, Cappelli, Serena, Rizzato, Silvia, Vicente, Rubén, and Caselli, Alessandro

Abstract

A highly reactive and selective catalytic system comprising Fe(III) and macrocyclic pyridine-containing ligands (Pc-L) for alkene oxidation by using hydrogen peroxide is reported herein. Four new stable iron(III) complexes have been isolated and characterized. Importantly, depending on the anion of the iron(III) metal complex employed as catalyst, a completely reversed selectivity was observed. When X=OTf, a selective dihydroxylation reaction took place. On the other hand, employing X=Cl resulted in the epoxide as the major product. The reaction proved to be quite general, tolerating aromatic and aliphatic alkenes as well as internal or terminal double bonds and both epoxides and diol products were obtained in good yields with good to excellent selectivities (up to 93 % isolated yield and d.r.=99 : 1). The catalytic system proved its robustness by performing several catalytic cycles, without observing catalyst deactivation. The use of acetone as a solvent and hydrogen peroxide as terminal oxidant renders this catalytic system appealing.

Published
2019

49. OS2.3 Updated results of REGOMA: A randomized, multicenter, controlled open-label phase II clinical trial evaluating regorafenib in relapsed glioblastoma <GBM> patients <PTS>

Author

Lombardi, G, de Salvo, G, Rudà, R, Franceschi, E, Eoli, M, Faedi, M, Pace, A, Lolli, I, Rizzato, S, Germano, D, Pasqualetti, F, Farina, M, Magni, G, Bellu, L, Caccese, M, Pambuku, A, Bergo, E, Indraccolo, S, Gardiman, M, Soffietti, R, and Zagonel, V

Subjects
Oral Presentations
Abstract

BACKGROUND: There is no established treatment regimen for recurrent GBM. GBMs have activation of multiple signaling pathways in the tumor microenvironment, including the receptor tyrosine kinases, VEGFR, FGFR, and PDGFR. Regorafenib (REG), an oral multikinase inhibitor, inhibits these angiogenic kinases and the mutant oncogenic kinases KIT, RET, and B‐RAF. MATERIAL AND METHODS: We present, after the first analysis, the updated results of REGOMA trial. The primary aim of this trial was to assess REG activity in prolonging overall survival (OS) in PTS with relapsed GBM after surgery and Stupp regimen (α = 0.2, 1-sided; β = 0.2). Secondary objectives were PFS, disease control rate (DCR), safety, quality of life (QoL); exploratory objectives included analysis of metabolic tissue biomarkers as possible predictors of response. PTS with histologically confirmed GBM, ECOG PS 0‐1, documented disease progression were randomized 1:1 to receive REG 160 mg/day (3 weeks on, 1 week off) or lomustine (LOM) 110 mg/m2 (every 6 weeks) until disease progression or unacceptable toxicity. Tumor response was evaluated by brain MRI every 8 weeks according to the RANO criteria. RESULTS: 119 PTS were randomized (n = 59 REG; n = 60 LOM) and stratified for surgery at recurrence; baseline characteristics, including MGMT methylation status, were balanced. Median age was 57.3 yrs; 27 PTS (22.7%) had surgery at recurrence, 22% and 23.3% in REG and LOM arm. At the time of analysis (cut-off date: Dec 31, 2017), median follow up was 15.4 months(m), 99 PTS had died. Median OS was 7.4m (95% CI 5.8–12.0) for REG and 5.6m (95% CI 4.7–7.3) for LOM (HR = 0.50, 80%CI 0.38–0.65; p = 0.0007; 1-sided Log-rank test); 12m-OS rates were 38.9% and 15.0% for REG and LOM. 6m-PFS rates were 16.9% and 8.3% (HR = 0.65; 95% CI 0.45‐0.95; p = 0.0223) for REG and LOM, DCR was 44.8% and 21.1% (p = 0.009) for REG and LOM. Grade ≥3 adverse events were reported in 56% and 40% for REG andLOM, no treatment-related deaths were reported. CONCLUSION: In this multicenter, randomized study, REG significantly improved OS, PFS and DCR in recurrent GBM PTS. REG treatment was feasible and well tolerated. QoL and biomarker analyses are ongoing. A phase 3 study will be planned

Published
2018

50. P01.040 Identification of a predictive biomarker of response to regorafenib in relapsed glioblastoma patients <REGOMA trial>

Author

Lombardi G, Indraccolo S, de Salvo G, Verza M, Magni G, Marica Eoli, Rudà R, Franceschi E, Faedi M, Lolli I, Rizzato S, Caccese M, Gardiman M, and Zagonel V

Subjects
Poster Presentations
Abstract

BACKGROUND: There is currently no predictive biomarker for anti-angiogenic drugs which could be used for patient selection purposes. Pre-clinical studies show that anti-angiogenic therapy exacerbates tumor hypoxia and activatesliver kinase B1 (LKB1)/AMP kinase (AMPK), a pathway involved in the regulation of tumor metabolism. Inspired by these findings, we investigated whether certain angiogenesis- and metabolism-related in situ biomarkers could predict response to regorafenib in the context of the phase 2 randomized REGOMA trial. MATERIAL AND METHODS: Immunohistochemistry was used to investigate expression in tumor sections of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor β (PDGFRβ), fibroblast growth factor receptor (FGFR), the angiopoietin receptor (Tie2),monocarboxylate transporter 1 and 4 (MCT1, MCT4), phosphorylated AMPK (pAMPK) and phosphorylated acetyl-CoA carboxylase(pACC), which is a canonical target of AMPK activity.Positivity for the markers was independently assessed by two analists blinded to clinical data and results of the REGOMA trial. The status of each biomarker was associated with clinical endpoints, including overall survival (OS) and progression free survival (PFS) in patients (PTS) with relapsed GBM treated either with regorafenib or lomustine. Radiological assessment was performed by RANO criteria. RESULTS: Between November 2015 and February 2017, 119 PTS were enrolled ﴾n=59 REG; n=60 LOM﴿ and stratified for surgery at recurrence; baseline characteristics were balanced. Biomarker analysis was performed in 85 PTS (71%), including 43 PTS of the REG arm and 42 PTS of the LOM arm. Among all markers analyzed, only pACC showed predictive value. In fact, median OS was 8.0 months (m) (95% CI 5.6-) for REG and 5.3m (95% CI 4.2–6.6) for LOM for pACC positive patients. HR 0.44 (95% CI 0.22–0.87), log rank p-value = 0.012; Test for interaction = 0.0419. CONCLUSION: In this randomized, controlled study we report for the first time a predictive impact of pACC expression in patients with relapsed GBM treated with regorafenib. These results suggest that integrity of the AMPK pathway is associated with clinical benefit from treatment with regorafenib.

Published
2018

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