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1. The effects of disease lesions and amoxicillin treatment on the physiology of SCTLD-affected corals

Author: Karen L. Neely, Robert F. Whitehead, and Michelle A. Dobler
Subjects: stony coral tissue loss disease, Orbicella faveolata, Montastraea cavernosa, photosynthesis, respiration, P/R, Science, General. Including nature conservation, geographical distribution, QH1-199.5
Abstract: Metrics of coral physiology can be used to identify changes in coral health due to environmental stressors or management actions. One of the most unprecedented stressors to Caribbean corals is the spread of stony coral tissue loss disease (SCTLD), which also resulted in the novel management action of in-water amoxicillin treatments on active disease lesions. Though highly effective at halting lesions and preventing coral mortality, possible unintended consequences of topical application of amoxicillin to coral tissue were unknown. We used in-water instrumentation to measure and compare photosynthesis (P), respiration (R), P/R ratios, and calcification of corals that were visually healthy, actively diseased, and diseased but treated with amoxicillin paste. Measurements occurred across three time points and two species – Orbicella faveolata and Montastraea cavernosa. Across all metrics, treatment type did not cause significant differences, indicating that neither SCTLD lesions nor amoxicillin treatments impacted the physiology of adjacent tissues. There were significant variations among time points, which may have resulted from changes to coral health across the reef, variations due to environmental variables, or other unknown factors. We suggest that physiological metrics could be an interesting way to fate track coral health across short- and long-term timeframes. We also conclude that amoxicillin treatments as a tool to halt SCTLD are not detrimental to respiration, photosynthesis, or calcification rates of adult corals.
Published: 2024
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2. Phase III Prospectively Randomized Trial of Perioperative 5-FU After Curative Resection for Colon Cancer: An Intergroup Trial of the ECOG-ACRIN Cancer Research Group (E1292)

Author: M. Margaret Kemeny, Fengmin Zhao, Arlene A. Forastiere, Paul Catalano, Stanley R. Hamilton, Brent W. Miedema, Nancy A. Dawson, Louis M. Weiner, Brian D. Smith, Bernard A. Mason, Stephen L. Graziano, Paul B. Gilman, Alan P. Venook, Harlan A. Pinto, Robert P. Whitehead, Peter J. O’Dwyer, and Al B. Benson
Subjects: Oncology, Surgery
Abstract: Background Studies suggest that adjuvant chemotherapy should be initiated at the earliest possible time. The Eastern Cooperative Oncology Group (ECOG) and Intergroup evaluated the effect of perioperative fluorouracil (5-FU) on overall survival (OS) for colon cancer. Patients and Methods This phase III trial randomized patients to receive continuous infusional 5-FU for 7 days starting within 24 h after curative resection (arm A) or no perioperative 5-FU (arm B). Patients with Dukes’ B3 and C disease received adjuvant chemotherapy per standard of care. The primary endpoint of the trial was overall survival in patients with Dukes’ B3 and C disease. The secondary objective was to determine whether a week of perioperative infusion would affect survival in patients with Dukes’ B2 colon cancer with no additional chemotherapy. Results From August 1993 to May 2000, 859 patients were enrolled and 855 randomized (arm A: 427; arm B: 428). The trial was terminated early due to slow accrual. The median follow-up is 15.4 years (0.03–20.3 years). Among patients with Dukes’ B3 and C disease, there was no statistically significant difference in OS [median 10.3 years (95% CI 8.4, 13.2) for perioperative chemotherapy and 9.3 years (95% CI 5.7, 12.3) for no perioperative therapy, one-sided log-rank p = 0.178, HR = 0.88 (95% CI 0.66, 1.16)] or disease-free survival (DFS). For patients with Dukes’ B2 disease, there was also no significant difference in OS (median 16.1 versus 12.9 years) or DFS. There was no difference between treatment arms in operative complications. One week of continuous infusion of 5-FU was tolerable; 18% of arm A patients experienced grade 3 or greater toxicity.
Published: 2022
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3. Phase III Prospectively Randomized Trial of Perioperative 5-FU After Curative Resection for Colon Cancer: An Intergroup Trial of the ECOG-ACRIN Cancer Research Group (E1292)

Author: M Margaret, Kemeny, Fengmin, Zhao, Arlene A, Forastiere, Paul, Catalano, Stanley R, Hamilton, Brent W, Miedema, Nancy A, Dawson, Louis M, Weiner, Brian D, Smith, Bernard A, Mason, Stephen L, Graziano, Paul B, Gilman, Alan P, Venook, Harlan A, Pinto, Robert P, Whitehead, Peter J, O'Dwyer, and Al B, Benson
Abstract: Studies suggest that adjuvant chemotherapy should be initiated at the earliest possible time. The Eastern Cooperative Oncology Group (ECOG) and Intergroup evaluated the effect of perioperative fluorouracil (5-FU) on overall survival (OS) for colon cancer.This phase III trial randomized patients to receive continuous infusional 5-FU for 7 days starting within 24 h after curative resection (arm A) or no perioperative 5-FU (arm B). Patients with Dukes' B3 and C disease received adjuvant chemotherapy per standard of care. The primary endpoint of the trial was overall survival in patients with Dukes' B3 and C disease. The secondary objective was to determine whether a week of perioperative infusion would affect survival in patients with Dukes' B2 colon cancer with no additional chemotherapy.From August 1993 to May 2000, 859 patients were enrolled and 855 randomized (arm A: 427; arm B: 428). The trial was terminated early due to slow accrual. The median follow-up is 15.4 years (0.03-20.3 years). Among patients with Dukes' B3 and C disease, there was no statistically significant difference in OS [median 10.3 years (95% CI 8.4, 13.2) for perioperative chemotherapy and 9.3 years (95% CI 5.7, 12.3) for no perioperative therapy, one-sided log-rank p = 0.178, HR = 0.88 (95% CI 0.66, 1.16)] or disease-free survival (DFS). For patients with Dukes' B2 disease, there was also no significant difference in OS (median 16.1 versus 12.9 years) or DFS. There was no difference between treatment arms in operative complications. One week of continuous infusion of 5-FU was tolerable; 18% of arm A patients experienced grade 3 or greater toxicity.
Published: 2021

4. Macroalgae has no effect on the severity and dynamics of Caribbean yellow band disease.

Author: Ivana Vu, Gillian Smelick, Sam Harris, Sarah C Lee, Ernesto Weil, Robert F Whitehead, and John F Bruno
Subjects: Medicine, Science
Abstract: By removing herbivores and promoting increases in macroalgae, overfishing is thought to indirectly cause coral disease and mortality. We performed three field manipulations to test the general hypothesis that overfishing and the subsequent alteration of coral reef trophic dynamics are a cause of coral epizootics. Specifically, we asked whether the presence of macroalgae can influence within- and among-colony spread rates of Caribbean Yellow Band Disease in Montastraea faveolata. Macroalgae were placed next to infected and healthy, adult and small coral colonies to measure effects on disease spread rate, coral growth and coral survival. Surprisingly, the addition of macroalgae did not affect disease severity or coral fitness. Our results indicate that macroalgae have no effect on the severity and dynamics of Caribbean Yellow Band Disease and that fisheries management alone will not mitigate the effects of this important epizootic.
Published: 2009
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5. Prospective Comprehensive Genomic Profiling of Primary and Metastatic Prostate Tumors

Author: Jeffrey P. Gregg, Paul Mathew, Jon Chung, Robert P. Whitehead, Primo N. Lara, Ethan Sokol, Gennady Bratslavsky, Richard T. Lee, Emmanuel S. Antonarakis, Jeffrey S. Ross, Neeraj Agarwal, Sumanta K. Pal, Andrea Necchi, Garrett M. Frampton, Sherri Z. Millis, Ninad Dewal, Vincent A. Miller, Siraj M. Ali, Chung, Jh, Dewal, N, Sokol, E, Mathew, P, Whitehead, R, Millis, Sz, Frampton, Gm, Bratslavsky, G, Pal, Sk, Lee, Rj, Necchi, A, Gregg, Jp, Lara, P, Antonarakis, E, Miller, Va, Ross, J, Ali, Sm, and Agarwal, N
Subjects: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Genomic profiling, business.industry, MEDLINE, Article, Management of prostate cancer, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Prostate, 030220 oncology & carcinogenesis, Internal medicine, Medicine, Treatment strategy, Prostate tumors, business
Abstract: PURPOSE Comprehensive genomic profiling (CGP) is increasingly used for routine clinical management of prostate cancer. To inform targeted treatment strategies, 3,476 clinically advanced prostate tumors were analyzed by CGP for genomic alterations (GAs) and signatures of genomic instability. METHODS Prostate cancer samples (1,660 primary site and 1,816 metastatic site tumors from unmatched patients) were prospectively analyzed by CGP (FoundationOne Assay; Foundation Medicine, Cambridge, MA) for GAs and genomic signatures (genome-wide loss of heterozygosity [gLOH], microsatellite instability [MSI] status, tumor mutational burden [TMB]). RESULTS Frequently altered genes were TP53 (44%), PTEN (32%), TMPRSS2-ERG (31%), and AR (23%). Potentially targetable GAs were frequently identified in DNA repair, phosphatidylinositol 3-kinase, and RAS/RAF/MEK pathways. DNA repair pathway GAs included homologous recombination repair (23%), Fanconi anemia (5%), CDK12 (6%), and mismatch repair (4%) GAs. BRCA1/2, ATR, and FANCA GAs were associated with high gLOH, whereas CDK12-altered tumors were infrequently gLOH high. Median TMB was low (2.6 mutations/Mb). A subset of cases (3%) had high TMB, of which 71% also had high MSI. Metastatic site tumors were enriched for the 11q13 amplicon ( CCND1/ FGF19/ FGF4/FGF3) and GAs in AR, LYN, MYC, NCOR1, PIK3CB, and RB1 compared with primary tumors. CONCLUSION Routine clinical CGP in the real-world setting identified GAs that are investigational biomarkers for targeted therapies in 57% of cases. gLOH and MSI/TMB signatures could further inform selection of poly (ADP-ribose) polymerase inhibitors and immunotherapies, respectively. Correlation of DNA repair GAs with gLOH identified genes associated with homologous recombination repair deficiency. GAs enriched in metastatic site tumors suggest therapeutic strategies for metastatic prostate cancer. Lack of clinical outcome correlation was a limitation of this study.
Published: 2019

6. Dual blockade of epidermal growth factor receptor and insulin-like growth factor receptor-1 signaling in metastatic pancreatic cancer: Phase Ib and randomized phase II trial of gemcitabine, erlotinib, and cixutumumab versus gemcitabine plus erlotinib (SWO

Author: Rakesh Gaur, Takeru Wakatsuki, Syma Iqbal, Robert P. Whitehead, Ramesh K. Ramanathan, Andrew M. Lowy, Heinz-Josef Lenz, Bryan Goldman, Charles D. Blanke, Philip A. Philip, and Jacqueline Benedetti
Subjects: Oncology, Cancer Research, medicine.medical_specialty, Performance status, biology, business.industry, Cixutumumab, Neutropenia, medicine.disease, Gemcitabine, chemistry.chemical_compound, Endocrinology, chemistry, Pancreatic cancer, Internal medicine, medicine, biology.protein, Epidermal growth factor receptor, Erlotinib, Erlotinib Hydrochloride, business, medicine.drug
Abstract: BACKGROUND Targeting a single pathway in pancreatic adenocarcinoma (PC) is unlikely to affect its natural history. We tested the hypothesis that simulataneous targeting of the epidermal growth factor receptor (EGFR) and insulin-like growth factor receptor–1 (IGF-1R) pathways would significantly improve progression-free survival (PFS) by abrogating reciprocal signaling that promote drug resistance METHODS This was a phase Ib/II study testing cixutumumab, combined with erlotinib and gemcitabine (G) in patients with untreated metastatic PC. The control arm was erlotinib plus G. The primary end point was PFS. Eligibility included performance status 0/1 and normal fasting blood glucose. Polymorphisms in genes involved in G metabolism and in the EGFR pathway were also studied RESULTS The phase I results (n = 10) established the safety of cixutumumab 6 mg/kg/week intravenously, erlotinib 100 mg/day orally, and G 1000 mg/m2 intravenously on days 1, 8, and 15 of a 28-day cycle. In the RP2 portion (116 eligible patients; median age, 63), the median PFS and overall survival (OS) were 3.6 and 7.0 months, respectively, on the cixutumumab arm, and 3.6 and 6.7 months, respecively, on the control arm. Major grades 3 and 4 toxicities with cixutumumab and control were elevation of transaminases, 12% and 6%, respectively; fatigue, 16% and 12%, respectively; gastrointestinal, 35% and 28%, respectively; neutropenia, 21% and 10%, respectively; and thrombocytopenia, 16% and 7%, respecively. Grade 3/4 hyperglycemia was seen in 16% of patients on cixutumumab. Grade 3 or 4 skin toxicity was similar in both arms of the study (< 5%). No significant differences in PFS by genotype were seen for any of the polymorphisms. CONCLUSIONS Adding the IGF-1R inhibitor cixutumumab to erlotinib and G did not lead to longer PFS or OS in metastatic PC. Cancer 2014;120:2980–2985. © 2014 American Cancer Society.
Published: 2014
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7. Phase II trial of romidepsin (NSC-630176) in previously treated colorectal cancer patients with advanced disease: a Southwest Oncology Group study (S0336)

Author: James L. Abbruzzese, Charles D. Blanke, Lucas Wong, Robert Chapman, John H. Ward, Philip J. Gold, Robert P. Whitehead, Kevin G. Billingsley, Cathryn Rankin, and Paulo M. Hoff
Subjects: Adult, Male, Oncology, medicine.medical_specialty, Maximum Tolerated Dose, Colorectal cancer, medicine.medical_treatment, Salvage therapy, Article, Romidepsin, Young Adult, Depsipeptides, Internal medicine, Humans, Medicine, Pharmacology (medical), Survival rate, Aged, Neoplasm Staging, Aged, 80 and over, Salvage Therapy, Pharmacology, Chemotherapy, Antibiotics, Antineoplastic, Dose-Response Relationship, Drug, Performance status, business.industry, Middle Aged, Prognosis, medicine.disease, Chemotherapy regimen, Survival Rate, Clinical trial, Treatment Outcome, Female, Colorectal Neoplasms, business, medicine.drug
Abstract: Introduction: Patients with metastatic colorectal cancer who progress on standard chemotherapy have limited treatment options. New and effective drugs are needed for these patients. Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Patients and methods: Patients were required to have pathologically verified, measurable, metastatic or locally advanced colorectal cancer that was surgically unresectable. They must have failed either one or two prior chemotherapy regimens, had performance status of 0–1, adequate bone marrow, renal and hepatic function, and no significant cardiac disease. Patients were treated with romidepsin at a dose of 13 mg/m2 as a 4-h iv infusion on days 1, 8, and 15 of a 28-day cycle. The study had a two stage design. The primary objective of the study was to determine the confirmed response probability in this group of patients treated with romidepsin. Results: Twenty-eight patients were registered to the study, two of whom were ineligible. One eligible patient refused all treatment and was not analyzed. For the 25 remaining patients, performance status was 0 in 16 patients and 1 in nine patients. Ten patients had received one prior chemotherapy regimen and fifteen 2 prior regimens. Out of the 25 eligible and analyzable patients accrued in the first stage of the protocol, no objective responses were observed and the study was permanently closed. Four patients had stable disease as the best response. Twenty-five patients were assessed for toxicity. No grade 4 or greater toxicities were seen. Fourteen of the 25 patients experienced grade 3 toxicities the most common of which were fatigue or anorexia. Conclusion: Romidepsin at this dose and schedule is ineffective in the treatment of patients with metastatic colorectal cancer after prior chemotherapy. Future trials might evaluate combinations of romidepsin with chemotherapeutic or other agents.
Published: 2008
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8. Evaluation and comparison of two commercially available targeted next-generation sequencing platforms to assist oncology decision making

Author: Robert James Penny, David Mallery, David M. Loesch, Khemka, Scott Morris, Hoff Br, Ashish Sangal, Robert P. Whitehead, Eric J. Thompson, Gingrich Sa, and Glen J. Weiss
Subjects: treatment decision making, Computer science, assay, Bioinformatics, Tumor tissue, DNA sequencing, OncoTargets and Therapy, platform, Oncology, cancer, next-generation sequencing, Pharmacology (medical), Treatment decision making, Original Research
Abstract: Glen J Weiss,1 Brandi R Hoff,1 Robert P Whitehead,1 Ashish Sangal,1 Susan A Gingrich,1 Robert J Penny,2 David W Mallery,2 Scott M Morris,2 Eric J Thompson,2 David M Loesch,2 Vivek Khemka1 1Cancer Treatment Centers of America, Western Regional Medical Center, Goodyear, AZ, USA; 2Paradigm Diagnostics, Phoenix, AZ, USA Background: It is widely acknowledged that there is value in examining cancers for genomic aberrations via next-generation sequencing (NGS). How commercially available NGS platforms compare with each other, and the clinical utility of the reported actionable results, are not well known. During the course of the current study, the Foundation One (F1) test generated data on a combination of somatic mutations, insertion and deletion polymorphisms, chromosomal abnormalities, and deoxyribonucleic acid (DNA) copy number changes at ~250× coverage, while the Paradigm Cancer Diagnostic (PCDx) test generated the same type of data at >5,000× coverage, plus provided messenger RNA (mRNA) expression levels. We sought to compare and evaluate paired formalin-fixed paraffin-embedded tumor tissue using these two platforms.Methods: Samples from patients with advanced solid tumors were submitted to both the F1 and PCDx vendors for NGS analysis. Turnaround time (TAT) was calculated. Biomarkers were considered clinically actionable if they had a published association with treatment response in humans and were assigned to the following categories: commercially available drug (CA), clinical trial drug (CT), or neither option (hereafter referred to as “None”).Results: The demographics of the 21 unique patient tumor samples included ten men and eleven women, with a median age of 56 years. Due to insufficient archival tissue from the same collection period, in one case, we used samples from different collections. PCDx reported first results faster than F1 in 20 cases. When received at both vendors on the same day, PCDx reported first results for 14 of 15 cases, with a median TAT of 9 days earlier than F1 (P
Published: 2015

9. Phase II trial of R115777 (NSC #70818) in patients with advanced colorectal cancer: A Southwest Oncology Group study

Author: Michael Tanaka, James L. Abbruzzese, Heinz-Josef Lenz, Marcus A. Neubauer, Sheryl McCoy, John S. Macdonald, Shaker R. Dakhil, Saul E. Rivkin, and Robert P. Whitehead
Subjects: Adult, Male, Oncology, medicine.medical_specialty, Colorectal cancer, medicine.medical_treatment, Antineoplastic Agents, Quinolones, Neutropenia, Internal medicine, Southwestern United States, medicine, Clinical endpoint, Humans, Pharmacology (medical), Survival analysis, Aged, Neoplasm Staging, Pneumonitis, Aged, 80 and over, Pharmacology, Chemotherapy, Leukopenia, Dose-Response Relationship, Drug, business.industry, Middle Aged, medicine.disease, Survival Analysis, Female, medicine.symptom, Colorectal Neoplasms, business, Febrile neutropenia
Abstract: Purpose: The purpose of this Phase II multi-institutional trial was to determine the efficacy and toxicity of R115777 in previously untreated patients with metastatic colorectal carcinoma. Patients and methods: Patients were required to have histologically confirmed colorectal cancer with distant metastatic disease that was not surgically curable. They could not have received prior chemotherapy for metastatic disease. R115777 was given at a dose of 300 mg p.o. twice a day for 21days every 28 days until tumor progression or toxicity or other reason for discontinuation occurred. The primary endpoint was to determine the confirmed response probability with this treatment. Results: There were 55 eligible patients accrued to the study. There were no complete responses, but one confirmed partial response for a confirmed response probability of 2% (95%CI 0–10%). Three additional patients had an unconfirmed partial response for an overall response probability of 7%. The time to treatment failure was 1.7 months and the estimated median survival was 8.1 months. One patient died of treatment related infection and there were 7 other patients with grade 4 toxicities consisting of neutropenia, leukopenia, febrile neutropenia and thrombocytopenia, depression, increased bilirubin, anemia, and pneumonitis/infiltrates. Conclusion: R115777 given as a single agent by this dose and schedule is ineffective in patients with metastatic colorectal cancer.
Published: 2006
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10. A phase II pilot study of high-dose 24-hour continuous infusion of 5-FU and leucovorin and low-dose PALA for patients with colorectal cancer: A Southwest Oncology Group study

Author: James L. Abbruzzese, Robert P. Whitehead, Stanley P. Balcerzak, Bach Ardalan, Jacqueline Benedetti, Ellen R. Gaynor, Stephen K. Williamson, and John S. Macdonald
Subjects: Adult, Male, Phosphonoacetic Acid, medicine.medical_specialty, Colorectal cancer, Continuous infusion, Leucovorin, Pilot Projects, Gastroenterology, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Pharmacology (medical), Neoplasm Metastasis, Infusions, Intravenous, Aged, Pharmacology, Response rate (survey), Aspartic Acid, Dose-Response Relationship, Drug, Group study, business.industry, Middle Aged, medicine.disease, Confidence interval, Survival Rate, Diarrhea, Treatment Outcome, Oncology, Anesthesia, Toxicity, Vomiting, Female, Fluorouracil, medicine.symptom, Colorectal Neoplasms, business
Abstract: Purpose: The purpose of this phase II multi-institutional study was to define the efficacy and toxicity of infusional 5-FU in combination with PALA and leucovorin in patients with advanced colorectal cancer. Patients and methods: Patients were required to have histologically confirmed colorectal cancer with distant metastases. The treatment regimen consisted of 5-FU 2600 mg/m2 as a 24-hours continuous infusion given once a week, concurrently with leucovorin (LV) at 500 mg/m2 as a 24-hour continuous infusion. PALA was administered 24 hours prior to 5-FU/LV at a dose of 250 mg/m2 iv over 15 minutes weekly. Patients were continued on the assigned treatment regimen until progression of disease, unacceptable toxicity, or the patient declined further therapy. Results: This study accrued 28 patients and all were eligible and evaluable for toxicity. Four patients had inadequate assessment of response and are considered non-responders. There was one complete response and five partial responses for an overall response rate of 6/28 or 21% (95% confidence interval 8–41%). Estimated median survival was 17.4 months (95% confidence interval 13.3–20.5 months). One patient died of a treatment related infection. This patient also had grade 4 diarrhea and vomiting. Conclusion: The combination of 5-FU, leucovorin, and PALA in the doses and schedule used here, produces a response rate similar to other modulated schedules of 5-FU with similar survival and toxicity profiles.
Published: 2004
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11. A phase II study of high-dose 24 hour continuous infusion 5-FU and leucovorin and low-dose PALA for patients with advanced pancreatic adenocarcinoma: A Southwest Oncology Group Study

Author: James L. Abbruzzese, John S. Macdonald, Stanley P. Balcerzak, Bach Ardalan, Robert P. Whitehead, J. Wendall Goodwin, Heinz-Josef Lenz, Jacqueline Benedetti, and Wolfram E. Samlowski
Subjects: Adult, Male, Phosphonoacetic Acid, medicine.medical_specialty, Bilirubin, Leucovorin, Phases of clinical research, Pilot Projects, Adenocarcinoma, Gastroenterology, Drug Administration Schedule, chemistry.chemical_compound, Internal medicine, Pancreatic cancer, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Pharmacology (medical), Prospective Studies, Infusions, Intravenous, Aged, Pharmacology, Response rate (survey), Aspartic Acid, Dose-Response Relationship, Drug, business.industry, Middle Aged, medicine.disease, Confidence interval, Surgery, Pancreatic Neoplasms, Survival Rate, Treatment Outcome, Oncology, chemistry, Toxicity, Vomiting, Female, Fluorouracil, medicine.symptom, business
Abstract: Purpose: The purpose of this phase II multi-institutional study was to define the efficacy and toxicity of infusional 5-FU in combination with PALA and leucovorin in patients with advanced pancreatic cancer. Patients and methods: Patients were required to have histologically confirmed pancreatic cancer that was locally advanced, unresectable or disseminated. The treatment regimen consisted of weekly 5-FU 2600 mg/m2 given concurrently with leucovorin at 500 mg/m2. Both drugs were administered by 24-hour continuous infusion. PALA was administered 24 hours prior to the administration of 5-FU/LV at a dose of 250 mg/m2 IV over 15 minutes weekly. Patients were continued on the assigned treatment regimen until progression of disease, unacceptable toxicity, or the patient declined further therapy. Results: This study accrued 30 patients. Four of these patients were ineligible. All 26 eligible patients were evaluated for toxicity. One patient had inadequate assessment of response and was considered a non-responder. Three of the twenty-six eligible patients had partial responses, for a response rate of 12% (95% confidence interval 2% to 30%). All 26 eligible patients have died and the median overall survival was 7 months (95% confidence interval: 5.2 to 9 months). Four patients experienced grade 4 toxicities, including bilirubin increase (2 patients), vomiting (1 patient) and non-local skin ulceration (1). Two patients discontinued therapy due to toxicity. Conclusion: The dual modulation of 5-FU with PALA and leucovorin in the dose and schedule used here, has a response rate similar to other single agents in pancreatic cancer and can result in some long term survival while having relatively mild toxicity.
Published: 2004
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12. A Phase II trial of vinorelbine tartrate in patients with disseminated malignant melanoma and one prior systemic therapy

Author: S. Spence McCachren, James Moon, J. Thaddeus Beck, Nerses S. Tchekmedyian, Robert P. Whitehead, Vernon K. Sondak, Evan M. Hersh, and Wolfram E. Samlowski
Subjects: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Skin Neoplasms, Dacarbazine, medicine.medical_treatment, Neutropenia, Vinblastine, Vinorelbine, Disease-Free Survival, Internal medicine, medicine, Humans, Neoplasm Metastasis, Melanoma, Aged, Chemotherapy, Leukopenia, Performance status, business.industry, Middle Aged, medicine.disease, Antineoplastic Agents, Phytogenic, Drug Resistance, Neoplasm, Injections, Intravenous, Female, Liver function, medicine.symptom, business, Febrile neutropenia, medicine.drug
Abstract: BACKGROUND Single-agent chemotherapy with dacarbazine continues to be the standard of care for the treatment of metastatic melanoma. However, there is a large population of patients who have failed first-line therapy and might benefit from additional treatment. In the current study, the authors evaluated the antitumor effects and toxicity of vinorelbine therapy in patients who had failed one prior systemic therapy. METHODS Patients were required to have a histologic diagnosis of melanoma and be of Stage IV with measurable disease, a Southwest Oncology Group (SWOG) performance status (PS) of 0–2, no evidence of brain metastases, and adequate bone marrow and liver function. Treatment was comprised of vinorelbine given at a dose of 30 mg/m2/week by intravenous bolus. RESULTS Twenty-four patients were registered to the study, 3 of whom were determined to be ineligible. The 21 eligible patients had a median age of 58 years with a SWOG PS of 0 in 7 patients, 1 in 13 patients, and 2 in 1 patient. There were no complete or partial responses observed, for a response rate of 0 of the 21 patients studied (95% confidence interval [95% CI], 0–16%); the study closed after the first stage of accrual. The estimated median progression-free survival was 2 months (95% CI, 1.5–3.3 months) and the estimated median overall survival was 6 months (95% CI, 3.7–8.3 months). There was one death due to febrile neutropenia reported, with six patients experiencing one or more Grade 4 toxicities, including neutropenia/granulocytopenia, leukopenia, dyspnea, and fatigue. CONCLUSIONS Despite impressive preclinical activity against melanoma, vinorelbine does not appear to have enough clinical activity to be of interest in previously treated patients with disseminated melanoma. The progression-free and overall survival results noted in previously treated patients in the current study were similar to results reported in prior SWOG Phase II trials in untreated patients. The group of previously treated patients may be used to evaluate new agents for the treatment of disseminated melanoma. Cancer 2004. © 2004 American Cancer Society.
Published: 2004
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13. Abstract CT134: Phase I/II trial of gemcitabine, nab-paclitaxel, and pembrolizumab in metastatic pancreatic adenocarcinoma

Author: Jessica Coats, Ashish Sangal, Robert P. Whitehead, Glen J. Weiss, Jordan Waypa, Vivek Khemka, Lisa Blaydorn, and Kayla McGahey
Subjects: Oncology, Cancer Research, medicine.medical_specialty, business.industry, Pembrolizumab, Metastatic Pancreatic Adenocarcinoma, Neutropenia, medicine.disease, Single Center, Rash, Gemcitabine, Internal medicine, Clinical endpoint, medicine, medicine.symptom, business, Survival rate, medicine.drug
Abstract: Background: Pembrolizumab (P) is a checkpoint inhibitor that blocks the interaction between programmed cell death protein 1 on T-cells and PD-L1 and PD-L2 on tumor cells. We conducted a single center phase Ib/II study of gemcitabine, nab-paclitaxel, and P (GNP) to evaluate the safety and efficacy in metastatic pancreatic adenocarcinoma (PDAC) (NCT02331251). Methods: PDAC patients (pts) with measurable disease, biopsy proven metastasis, adequate laboratory tests, and KPS ≥ 70% were eligible and received gemcitabine and nab-paclitaxel on days 1 and 8 and P 2 mg/kg on day 1 every 21 days until progression or toxicity. Safety monitoring, RECIST 1.1, and irRECIST assessments were conducted. Response imaging was performed prior to cycle 4, then every 3 months. Results: 17 pts with a median age of 56 were treated. 11 were women and all had a KPS of at least 80%. Any grade drug-related treatment adverse events (AEs) occurred in 100% of patients; the most common (>20% pts) were anemia, thrombocytopenia, hypoalbuminemia, ALT and ALK elevation, fatigue, rash, nausea, vomiting, diarrhea, fever, insomnia, and edema in limbs. Grade 3 events (>10% pts) were hyponatremia, thrombocytopenia, and neutropenia (2 case each, 11.8%). Dose-limiting toxicities occurred only in previously treated PDAC (grade 3 thrombocytopenia; grade 3 fatigue and thrombocytopenia) and the cohort was subsequently divided into chemo naïve and previously treated pts. The recommended phase II dose (RP2D) for chemo naïve PDAC was gemcitabine 1000 mg/m2 and nab-paclitaxel 125 mg/m2. Of the 8 evaluable chemo naïve PDAC, the disease control rate (partial response [PR] + stable disease[SD]) was 100%. There were 2 PR on treatment for ~11 and 15 months and there are 3 pts still too early to assess. The primary endpoint of >15% complete response was not met. The best response for previously treated pts was SD. For chemo naïve and previously treated PDAC, the 6-month survival rate is 89% (with 3 pts still on study less than 3 months) and 40%, respectively. The median PFS and OS is 5 and 10.3 months and 2.1 and 4.1 months for chemo naïve and previously treated pts, respectively. Conclusions: GNP can be safely given to chemo naïve PDAC pts. Efficacy appears to be similar to slightly improved over previously reported results for standard weekly x 3 every 28 day gemcitabine and nab-paclitaxel dosing. Citation Format: Glen J. Weiss, Jordan Waypa, Jessica Coats, Lisa Blaydorn, Kayla McGahey, Ashish Sangal, Robert P. Whitehead, Vivek Khemka. Phase I/II trial of gemcitabine, nab-paclitaxel, and pembrolizumab in metastatic pancreatic adenocarcinoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr CT134. doi:10.1158/1538-7445.AM2017-CT134
Published: 2017
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14. Epothilone B Analogue

Author: Robert P. Whitehead
Published: 2014
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15. Phase II Trial of CI-980 in Patients with Disseminated Malignant Melanoma and no Prior Chemotherapy – A Southwest Oncology Group Study

Author: Vernon K. Sondak, Sarah A. Taylor, John R. Eckardt, Lawrence E. Flaherty, Mukund S. Didolkar, Robert P. Whitehead, Joseph M. Unger, and Wolfram E. Samlowski
Subjects: Adult, Male, medicine.medical_specialty, Skin Neoplasms, Pyridines, Nausea, Anemia, medicine.medical_treatment, Renal function, Antineoplastic Agents, Gastroenterology, Drug Administration Schedule, Internal medicine, medicine, Humans, Pharmacology (medical), Melanoma, Survival rate, Aged, Pharmacology, Chemotherapy, business.industry, Middle Aged, medicine.disease, Surgery, Survival Rate, Clinical trial, Treatment Outcome, Oncology, Pyrazines, Vomiting, Female, Carbamates, medicine.symptom, business
Abstract: Malignant melanoma is increasing in frequency at a rapid rate in the United States. Metastatic disease is chemoresistant with DTIC considered the most active single agent. CI-980 is a synthetic mitotic inhibitor that blocks the assembly of tubulin and microtubules. It has shown cytotoxic activity against a broad spectrum of murine and human tumor cell tines. CI-980 can cross the blood brain barrier, is effective when given orally or parenterally, and is active against multidrug resistant cell lines overexpressing P-glycoprotein. In this trial, patients with disseminated melanoma with measurable disease, SWOG performance status of 0-1, no prior chemotherapy or immunotherapy for metastatic disease, and adequate hepatic and renal function, were enrolled. Treatment with CI-980 was given by 72 h continuous i.v. infusion at a dose of 4.5 mg/m2/day, days 1-3 every 21 days. Twenty-four patients were registered on this study with no patients ineligible. They ranged in age from 33-78 with performance status of 0 in 15 patients and 1 in 9 patients. Nineteen patients had visceral disease with 12 having liver involvement. There were no confirmed responses. The overall response rate was 0% (95% CI 0%-14%). The median overall survival is eleven months (95% CI 4-14 months). The most common toxicities were hematologic and consisted of leukopenia/granulocytopenia and anemia, with nausea/vomiting and malaise/fatigue/weakness also frequent. CI-980 administered at this dose and schedule has insufficient activity in the treatment of disseminated malignant melanoma to warrant further investigation.
Published: 2001
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16. Relationship Between Activated Protein C Resistance and Central Venous Device-Related Complications

Author: Yi-Kong Keung, Mary Gilbert, Everardo Cobos, David Morgan, Annabel Barber, Melody Staton, Cathy Ronaghan, and Robert P. Whitehead
Subjects: Urokinase, medicine.medical_specialty, business.industry, Incidence (epidemiology), Cancer, Hematology, General Medicine, medicine.disease, Thrombosis, Gastroenterology, Surgery, Catheter, Internal medicine, Bacteremia, medicine, Activated protein C resistance, business, Protein C, medicine.drug
Abstract: We studied the relationship between activated protein C (APC) resistance and the central venous devices (CVD)-related complications in 61 cancer patients (44 females `and 17 males, median age 50 years, 71 CVD) from November 1994 to November 1995. Two patients (3.3%) had APC resistance, i.e., APC ratio < 2. Twelve episodes of bactercmia, 8 site infections, 31 cases of CVD dysfunction requiring urokinase (UK), and 3 CVD-retated thromboses were noted. With Cox's proportional hazard models, low APC ratios and high d-dimer levels were significantly associated with CVD-related bacteremia (p = 0.0207 and 0.0210). Such an association was not observed with site infection and CVD dysfunction. The incidence of thrombosis was too low to be analyzed. However, one patient with APC resistance developed subclavian vein thrombosis, leading to eventual removal of the catheter. The prevalence of APC resistance in cancer patients and its association with bacteremia are discussed. Key Words : Activated protein C resistance—Central venous catheters—Bacteremia— Catheter site infection—Thrombosis.
Published: 1997
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17. A phase II study of farnesyl transferase inhibitor R115777 in pancreatic cancer: A Southwest oncology group (SWOG 9924) study

Author: James L. Wade, James L. Abbruzzese, Sheryl McCoy, John S. Macdonald, Jeffrey K. Giguere, Robert P. Whitehead, and Syma Iqbal
Subjects: Adult, Male, medicine.medical_specialty, Anemia, Phases of clinical research, Adenocarcinoma, Quinolones, Proto-Oncogene Mas, Gastroenterology, Internal medicine, Pancreatic cancer, Farnesyltranstransferase, Humans, Medicine, Pharmacology (medical), Survival rate, Fatigue, Aged, Aged, 80 and over, Pharmacology, Performance status, business.industry, Farnesyl Transferase Inhibitor, Cancer, Nausea, Middle Aged, medicine.disease, Surgery, Pancreatic Neoplasms, Survival Rate, Treatment Outcome, Oncology, Female, business
Abstract: Ninety per cent of pancreatic adenocarcinomas (PC) contain mutations of the K-Ras proto-oncogene resulting in constitutively activated Ras protein. A critical step in Ras activation is farnesylation of Ras protein. Farnesyl transferase inhibitors are compounds that inhibit farnesylation. We report the results of a phase II trial of R115777, an oral farnesyl transferase inhibitor, in patients with surgically incurable locally advanced or metastatic PC. Between 6/1/2000 and 11/20/2001, 58 cases were accrued, 53 of whom were eligible and analyzable. Patients were required to have a performance status (PS) 0 to 1, be able to take oral medications, and to have adequate renal, hepatic, and hematologic functions. Fifty-five percent were male. Median age was 64.7 years (38.9 to 80.6), and patients had no previous systemic therapy for advanced PC. Treatment consisted of R115777 300 mg po bid given for 3 out of every 4 weeks. Toxicities were as follows: Grade 3 in 19/53 (36%), grade 4 in 53 (173%), and grade 5 in 53 (8%). Most frequent toxicities were: anemia 35/53 (66%), fatigue and malaise 33/53 (62%), nausea 31/53 (58%). Grade 5 toxicities included: thromboembolism 1, infection 2, other 1. Median survival was 2.6 months (mo) (95% CI 2.1-3.6), 6-mo survival is 19% (95% CI, 8-29%), median time to treatment failure was 1.4 mo (95% GI 1.1-1.6). R115777 is ineffective as monotherapy in advanced pancreatic cancer.
Published: 2005
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18. Abstract 3138: Changes in tumor cell-free DNA copy number instability (CNI) predict therapeutic response in metastatic cancers

Author: Heather Barilla, Robert P. Whitehead, Glen J. Weiss, Vivek Khemka, Rhiannon Cubello, Donald P Braun, Madappa N. Kundranda, Kirsten Bornemann-Kolatzki, Howard B. Urnovitz, Ekkehard Schütz, Ashish Sangal, and Julia Beck
Subjects: Oncology, Cancer Research, Chemotherapy, medicine.medical_specialty, Pathology, Colorectal cancer, medicine.medical_treatment, Cancer, Tumor cells, Biology, medicine.disease, 030226 pharmacology & pharmacy, Free dna, Lymphoma, 03 medical and health sciences, 0302 clinical medicine, Stable Disease, 030220 oncology & carcinogenesis, Internal medicine, medicine, Digital polymerase chain reaction
Abstract: Background: Tumor cell-free DNA (cfDNA) has the potential to provide minimally invasive patient specific biomarkers to monitor tumor burden. Gains and losses of chromosomal regions - as a hallmark of cancer - have been detected in plasma as copy number aberrations (CNAs), and for several cancers a relation to tumor size has been reported. Longitudinal observations during anti-cancer therapy have been mostly anecdotal. We measured CNAs changes during treatment by computing a genomic copy number instability index (CNI) of cfDNA to evaluate its potential to predict cytotoxic chemotherapy (chemo) response. Methods: 24 patients (pts) with advanced esophageal cancer (EC; n = 2), colorectal cancer (CRC; n = 3), non-Hodgkin lymphoma (NHL; n = 3), pancreatic ductal adenocarcinomas (PDAC; n = 4), and non-small cell lung cancer (NSCLC; n = 12) were included and assessable for response. DNA was extracted from pre-treatment plasma samples at baseline and sequentially for up to six cycles of chemotherapy. Copy-numbers were called from shotgun sequencing (Illumina) after mapping and quality filtering reads were counted in 5.5MBp windows (sliding) yielding a read coverage of 24,000-fold per bin. The read counts were transformed into log2 ratios and converted into a score based on Gaussian transformations. Concentration of total cfDNA was determined by digital PCR. Treatment response by imaging was recorded by RECIST 1.1 or EORTC PET/CT criteria. For pts with baseline CNI>40 (representing the 99.99% level for non-cancer healthy controls), CNI change was considered predictive of response or stable disease when there was a reduction of CNI ≥50% relative to baseline. Disease progression was demonstrated when: 1) CNI was ≥50% over nadir and Citation Format: Glen J. Weiss, Julia Beck, Donald P. Braun, Kirsten Bornemann-Kolatzki, Heather Barilla, Rhiannon Cubello, Ashish Sangal, Robert P. Whitehead, Madappa Kundranda, Vivek Khemka, Howard B. Urnovitz, Ekkehard Schutz. Changes in tumor cell-free DNA copy number instability (CNI) predict therapeutic response in metastatic cancers. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 3138.
Published: 2016
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19. A Phase II Trial of Concomitant Human Interleukin-2 and Interferon-??-2a in Patients with Disseminated Malignant Melanoma

Author: Nancy Moldawer, Julia Pfile, Gary R. Jones, Robert P. Whitehead, Jacob Zeffren, Dilip Patel, Robert A. Figlin, Marc L. Citron, and Dan Levitt
Subjects: Adult, Male, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Immunology, Alpha interferon, Interferon alpha-2, Gastroenterology, Drug Administration Schedule, Sepsis, Internal medicine, medicine, Humans, Immunology and Allergy, Melanoma, Interferon alfa, Aged, Pharmacology, business.industry, Interferon-alpha, Immunotherapy, Middle Aged, medicine.disease, Recombinant Proteins, Surgery, Regimen, Diarrhea, Concomitant, Interleukin-2, Female, medicine.symptom, business, medicine.drug
Abstract: Interleukin-2 (IL-2) and alpha-interferon have each shown antitumor activity in patients with disseminated malignant melanoma. Because animal studies suggest enhanced activity for the combination over each agent used alone, this trial using a relatively low-dose outpatient regimen was undertaken. IL-2 at a dose of 2 x 10(6) U/m2/day (Roche units) was given by continuous intravenous infusion for 4 days a week with interferon-alpha-2a at a dose of 6 x 10(6) U/m2/day given by s.c. or i.m. injection on days 1 and 4 of each treatment week. One cycle consisted of 4 consecutive weeks of treatment followed by a 2-week rest period. Fourteen patients were entered in this study. No complete or partial responses were seen. One patient required dose reduction because of grade 3 diarrhea and two patients had interruption of treatment because of central-line-related sepsis. Fatigue was common in all patients. This low-dose combination regimen of IL-2 and alpha-interferon does not appear to be better than the single agents used alone in optimal dosage.
Published: 1993
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20. HIES

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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21. Hereditary Motor and Sensory Neuropathy

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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22. Hyperostosis Corticalis Deformans Juvenilis

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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23. Human Transmissible Spongiform Encephalopathies

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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24. Hereditary Nephritis

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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25. Hearing Loss, Noise-induced and Acoustic Trauma

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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26. Hypersensitivity Type I

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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27. Hypoglycemia, Non-islet Cell

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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28. Hyper-IgE Recurrent Infection Syndrome

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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29. Hypermobility Syndrome

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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30. Hyperostose en Coulée

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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31. Hyperekplexia, Hereditary

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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32. Hand-Heart Syndrome

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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33. Hyperostosis, Infantile Cortical

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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34. Hyperparathyroidism, Primary

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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35. Hypothyroidism, Nongoitrous Congenital

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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36. β-Hexosaminidase α-Subunit Deficiency

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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37. Hypoxic Ischemia

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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38. High Blood Triglycerides

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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39. Hypersensitivity Vasculitis

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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40. Hyperthyroidism due to Thyroid Autonomy

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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41. Hyperhomocysteinemia: Genetic Basis and Arterial Thrombosis

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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42. Hyperthyroidism, Sporadic Non-autoimmune

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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43. Hereditary Renal Hypouricemia

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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44. Huntington’s Chorea

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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45. Hepatitis, Acute

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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46. Hauptmann-Thannhauser Muscular Dystrophy

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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47. High Triglycerides

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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48. Hemophilia B

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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49. Human RSV

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
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50. Hypotrichosis-Lymphedema-Telangiectasia Syndrome

Author: Dieter Metze, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, Jae-Hwan Nam, Yoichi Matsubara, Keiya Tada, Seda Sancak, Ralf Paschke, Susan Kupka, Stefan K. Plontke, Hans-Peter Zenner, Gohar Azhar, Jeanne Y. Wei, Y. James Kang, Katsuhiko Yoshizawa, Abraham Nyska, Graeme Jones, Kathy Triantafilou, Philipp M. Lepper, Johannes G. Bode, Clifford E. Kashtan, Klaus Schümann, Günter Weiss, Christine Skerka, Christoph Licht, Peter F. Zipfel, Hugo ten Cate, Mark Oette, Dieter Häussinger, Isabelle L. Ruel, Patrick Couture, Benoît Lamarche, Sören V. Siegmund, Stephan L. Haas, Manfred V. Singer, Tobias Heintges, Ralf Kubitz, Andreas Erhardt, Frank Lammert, Johann Lorenzen, Hubert E. Blum, Darius Moradpour, Georg Merker, Matthias Wettstein, Mónica Guevara, Pere Ginès, Hugo Ten Cate, Ulrich Heininger, Markus Pfister, Marcus Schmitt, Arend F. L. Schinkel, Don Poldermans, Jeroen J. Bax, Heimo Mairbäurl, Peter Bärtsch, Georg H. Merker, Percy Chiu, Richard S. Legro, William L. Nyhan, Sandeep S. Dave, Jürgen Kohlhase, Arne W. J. H. Dielis, S. Harvey Mudd, Christian Simon, Oliver Schildgen, Suncanica Ljubin Sternak, Gordana Mlinaric-Galinovic, Eggert Stockfleth, Ingo Nindl, Inga Zerr, Mathias Bähr, Nicole Stankus, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jonas Denecke, Shoichi Katsuragi, Bodo Grimbacher, Cristina Woellner, Steven Holland, Christian A. Koch, Michael T. Geraghty, Peter L. M. Jansen, Robert P. Whitehead, Edward M. Brown, Mei Bai, T. John Martin, Joaquin Escribano, Victor M. Garca Nieto, Patrick TS Ma, Lucia K Ma, Alexander K. C Leung, Angelika F. Hahn, Mallikarjuna Nallegowda, Upinderpal Singh, Mangajji R. Umapathi, Rakesh Kumar, Raffaele Badolato, Benjamin Glaser, Ruth Schreiber, Daniel Landau, Goo Taeg Oh, Carla Kallen, Joel Michels Topf, Patrick Murray, Jaime Tejedor, Manish Kumar Varshney, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Bernd Hoppe, Albrecht Hesse, Geoffrey N. Hendy, David E. C. Cole, Charles R. Nolan, Haruo Shintaku, Hiroshi Ichinose, Henry J. Mankin, Gabriel I. Uwaifo, Bettina C. Reulecke, Werner Heppt, Annette Cryer, Rade Tomic, Jesse Roman, Jan Rémi, Soheyl Noachtar, Miki Nagase, Toshiro Fujita, Angel Cogolludo, Jason X.-J. Yuan, Lewis J. Rubin, Manning R. Davis, T. Balakrishna Poduval, Saurabh Chatterjee, Hulya Iliksu Gozu, Markus Eszlinger, Rifat Bircan, Julia Lüblinghoff, Julia Lüblighoff, Roland Pfäffle, Shui-Ping Zhao, Hui-Jun Ye, Jens Mogensen, Rejin Kebudi, Sezer Saglam, Michael A. Becker, John R. Asplin, Robert W. Gotshall, Hubert Scharnagl, Winfried März, John A. Sayer, Simon H. Pearce, James J. Paparello, Philip J. Klemmer, Abhijit V. Kshirsagar, Patrick T. S. Ma, Lucia K. Ma, Marco Castori, Roswitha Siener, Pirmin Habermehl, Markus Knuf, Christoph Michalski, Jörg Kleeff, Annette Richter-Unruh, Denis J. Headon, Paul A. Overbeek, Alanna F. Bree, Hendrica Belge, Eva Riveira-Munoz, Olivier Devuyst, Stefanie Weber, Michael L. Moritz, Juan Carlos Ayus, Simon H. S. Pearce, Michael P. Whyte, Masafumi Fukagawa, Motoko Tanaka, Harriet S. Tenenhouse, Angelika Gutenberg, Patrizio Caturegli, Christy T. Oswalt, Pirooz Eghtesady, Manish Suneja, Christie P. Thomas, Hirokazu Sasaki, Tetsuo Yukioka, Maurice A. M. Van Steensel, Rongqian Wu, Ping Wang, Giora Feuerstein, Robert Ruffolo, Hyder A. Jinnah, James C. Harris, Holger K. Eltzschig, and Almut Grenz
Published: 2009
Full Text: View/download PDF

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