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Uvod: Nasljedna gingivna fibromatoza (NGF) rijetka je bolest koju obilježava povećanje gingive, no boja desni ostaje normalna, a konzistencija je dobra i čvrsta. Taj rast može potaknuti uporaba lijekova i nakupljanje plaka. Terapija izbora za to kliničko stanje jest kirurško uklanjanje povećanoga gingivnog tkiva ili vađenje svih zuba. Prikaz slučaja: U naš centar upućena je 20-godišnja Brazilka s posebnim potrebama zbog pretjeranog povećanja gingive. Od lijekova je uzimala Carbamazepin i Gardenal. Prema kliničkoj slici i obiteljskoj anamnezi, konačna dijagnoza zbog povećanja gingive bila je NGF. Odlučeno je da je potrebna stomatološka terapija, uključujući osnovno parodontno liječenje, restauracije, pečaćenja i gingivoplastiku s unutarnjim rezovima. Posebno se pazilo na to da se pritom ništa ne promijeni u primjeni antikonvulzivnih lijekova koje je uzimala. Pacijentica je nakon toga praćena sedam godina i hiperplazija gingive nije se ponovno pojavila zahvaljujući stalnom profesionalnom nadzoru i kućnoj kontroli zubnoga plaka., Introduction: Hereditary gingival fibromatosis (HGF) is a rare disease characterized by gingival enlargement, normal color with benign and firm consistency. This growth may be exacerbated by use of drugs and plaque build-up. The treatment for this clinical condition is surgical excision of the enlarged gingival tissue or the extraction of all teeth. Case Report: A 20-year-old Brazilian female handicapped patient with a chief complaint of exaggerated gingival enlargement who had been prescribed Carbamazepine and Gardenal was referred to our center. According to the clinical presentation and family history, the final diagnosis of gingival enlargement was HGF. Full dental treatment was performed, including basic periodontal treatment, restorations, sealants, and gingivoplasty with internal bevel. Special care was taken to ensure that there was no change in patient’s anticonvulsant medication. The patient has been monitored for seven years without signs of recurrence of gingival hyperplasia due to constant professional and home control of plaque.