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Cardiovascular diseases are the leading cause of death in Brazil. The pulse wave velocity (PWV) is an independent cardiovascular risk factor detecting arterial stiffness, correlated to age, among other variables

Background: Cardiovascular diseases are the main cause of death worldwide. In this setting, Neck Circumference (NC) and Pulse Wave Velocity (PWV) are simple and valuable tools for an early evaluation of cardiovascular risk through the assessment of upper body obesity and arterial stiffness. However, the associations between both measurements have not been systematically explored. Methods: A population-based cross-sectional study representative of a neighborhood of Salvador-BA, Brazil. Data were collected between December 2016 and May 2019, and comprise 130 individuals for the present study. Variables such as age, sex, education levels and NC were analyzed to verify their associations with PWV status. Correlations between PWV and NC were performed to further depict their association. Results: There was a predominance of patients with elevated PWV. The subgroup of patients aged 60 years or older presented the largest proportion of PWV alterations over normal results. There was a majority of women in the study population and sex could not determine PWV status. There was a predominance of concomitant elevation of NC and PWV in the studied population. NC measurements could distinguish PWV status from women and the study population. NC and PWV had a positive and statistically significant correlation for women and for the general population. Conclusion: These findings suggest a possible association between upper body obesity and vascular homeostasis impairment. Therefore, screening patients with both measurements could prove relevant to better identify subclinical vascular perturbations and further delimitate prognosis related to cardiovascular events potentially associated with them. •Elevation of pulse wave velocity (PWV) was associated with the increase of age. •Frequency of patients with elevated PWV and neck circumference was predominant. •Neck circumference and pulse wave velocity were positively correlated.

Introduction: Pulse wave velocity (PWV) is considered a gold standard for assessment of arterial stiffness [1]; neck circumference (NC) is a good anthropometrical indicator of fat accumulation in the upper body region [2]. Methods: A population-based cross-sectional study representative of a neighborhood of Salvador-BA, Brazil, distributed in 12 census tracts according to the Brazilian Institute of Geography and Statistics. The overall sample is randomized in adults from the assigned area, from December 2016 to May 2019 comprise 145 people. Individual and household records are filled out PWV was the measuring velocity between the carotid and right femoral wave, coupled to the electrocardiogram. The committee for research on human subjects of the FTC approved the protocol (No1827621). The measurement equipment was the flattening tonometer SphygmoCor® apparatus (XCEL, AtCor Medical, Sydney, Australia). The NC was obtained by using an inelastic fiberglass tape measure based on the height of the cricothyroid cartilage. The values ≥37 cm for men or ≥34 cm for women were used for their classification [3]. The frequency and descriptive measures, Spearman’s linear correlation coefficient between the laboratory tests and adjusted PWV. STATA v.12 software was used for treatment and generation of results. The level of statistical significance was set at 5%. Results: There was a predominance of women (70.3%). The correlation is the same for both sexes (r = 0.30), a weak positive, however it was statistically significant for women (p = 0.0031). Conclusion: The NC and PWV measurements showed a weakly positive. There was a statistically significant correlation for women.

Introduction: Central Pressure (PC) has shown to be more reliable in cardiovascular (CV) mortality (1); Salt intake and excretion seems to lead to an increase in this pulsatile component of the arterial flow (2, 3). C entral Pulse Pressure (PPc) data is very few. Methods: A population-based cross-sectional study representative of a poor and mixed-race neighborhood of Salvador-B A, Brazil, distributed in 12 census tracts according to the Brazilian Institute of Geography and Statistics. The overall sample is randomized in adults from the assigned area, from December 2016 to May 2018 comprise 110 people. Individual and household records are filled out. The central pressure, measured in the radial artery, obtained through aplanation tonometry, using the SphygmoCor® (XCEL, AtCor Medical, Sydney, Australia (2), with operation index ≥85%. PP c measured by systolic central pressure minus diastolic central pressure. 24-hour urine samples were collected. Urinary sodium (US) measured by the selective ion electrode, ADVIA1800® (SiemensHealthcare Japan/Canada). The committee for research on human subjects of the FTC approved the protocol (No1827621). Median, interquartile range, Spearman’s linear correlation coefficient between PPc and sodium stratified by sex, using STATA v.12 software for data base management and statistical analysis. The level of statistical significance was set at 5%. Results: 71,8% female, mean age 49,7 ± 16y. Median excretion rate of sodium was, in male,133,2 ± 82 mEq/l (In general 126,4 ± 84). In male was a significance negative correlation (r = −0,43;p = 0,01)between PPC and US excretion. Conclusion: There was a correlation between the values of PPc and UR in men (fig.1). These results need future best understanding.