Search

Your search keyword '"Rohilla, Manish"' showing total 335 results
Start Over Author "Rohilla, Manish"
335 results on '"Rohilla, Manish"'

5. Cytopathology of Breast Cancer

Author

Rohilla, Manish, Srinivasan, Radhika, Sharma, Suresh Chander, editor, Mazumdar, Alok, editor, Kaushik, Robin, editor, and Bose, Shashanka Mohan, Editor-in-Chief

Published
2022
Full Text
View/download PDF

9. Gray zone Bethesda category III – Atypia of undetermined significance lesions of the thyroid: Potential diagnostic issues and image morphometry as a useful adjunct to cytomorphology.

Author

Saini, Tarunpreet, Kundu, Reetu, Rohilla, Manish, Gupta, Parikshaa, Gupta, Nalini, Srinivasan, Radhika, Saikia, Uma Nahar, and Dey, Pranab

Abstract

Objective: Atypia of undetermined significance (AUS) is an indeterminate category which presents a significant challenge for pathologists and clinicians. The management options are dependent on the rate of malignancy for a given populace. Material and Methods: This is a retrospective analysis of 61 cases of the AUS Bethesda category III with grouping into neoplastic and non-neoplastic according to the histopathology data and clinical follow-up. Detailed cytomorphological features were analyzed and image morphometry was done using image J software. Student's t -test was used. Results: Out of the total 61 cases, 35 were neoplastic cases of AUS (histopathology proven), and 26 were non-neoplastic (on follow-up) cases. The risk of neoplasia and risk of malignancy observed were 57.4% and 47.5%, respectively. Neoplastic cases displayed prominent intranuclear inclusions (54%) and pseudopapillary clusters (20%). Majority of non-neoplastic cases revealed fine chromatin (96%) and pale chromatin (4%) while among neoplastic cases, 14% showed pale chromatin. Neoplastic cases showed moderate to marked nuclear pleomorphism (20%) compared to non-neoplastic cases which were monomorphic to mildly pleomorphic. None of the non-neoplastic cases exhibited frequent nuclear overlapping, nuclear grooving, or nucleoli which emphasizes the need for scrutiny of smears for these features. On image morphometry, cases with malignant outcome had larger nuclear area, perimeter, diameter, and nuclear density which were statistically significant. Conclusion: The study illustrates the importance of identifying subtle cytomorphological features and usefulness of image morphometry as an adjunctive objective tool in AUS cases. This helps in making an accurate cytological diagnosis which guides the treating clinician regarding surgical management or need for clinical follow-up. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

13. Utility of Image Morphometry in the Atypical Urothelial Cells and High-Grade Urothelial Carcinoma Categories of the Paris System for Reporting Urinary Cytology.

Author

Sharan, K.C., Rohilla, Manish, Dey, Pranab, Srinivasan, Radhika, Kakkar, Nandita, and Mavuduru, Ravimohan S.

Subjects
*RISK assessment, *CYTODIAGNOSIS, *CANCER invasiveness, *DESCRIPTIVE statistics, *RETROSPECTIVE studies, *TRANSITIONAL cell carcinoma, *URINALYSIS, *CYTOPLASM, *CELL nuclei, *BLADDER, *DIGITAL image processing, *DATA analysis software, *SENSITIVITY & specificity (Statistics), *EVALUATION, *DISEASE risk factors
Abstract

Introduction: Urinary cytology (UrCy) is highly sensitive to diagnosing high-grade urothelial carcinoma (HGUC) but cannot predict muscularis propria invasion. Further, the atypical urothelial cell category (AUC) may have variable outcomes. Image morphometry (IM) may be a valuable adjunct technique in this setting. Hence, we evaluated IM in the AUC and HGUC categories to improve the diagnostic performance. Materials and Methods: The following six nuclear parameters were evaluated by IM on 3150 cells: nucleo-cytoplasmic (N:C) ratio, nuclear area, diameter, perimeter, standard deviation of the nuclear area (SDNA; pleomorphism) and integrated density (ID; nuclear chromasia), using the ImageJ software, in three cohorts based on the histopathology outcome: 20 cases of AUC – benign non-neoplastic outcome (AUC-B); 22 cases of HGUC Muscle invasive (HGUC-MI) and 21 cases of HGUC non-muscle invasive (HGUC-MF). Results: A retrospective analysis of urine cytology. The patient's ages ranged from 36 to 85 years, with a mean age of 60.6. The male-to-female ratio was 5.4:1. A total of 20 cases of AUC-B and 43 cases of HGUC were selected for IM analysis. HGUC cases had higher nuclear parameters than AUC-B, and HGUC-MI had higher SDNA, ID, diameter, and area than HGUC-MF. SDNA and ID predict muscularis propria invasion in HGUC. Conclusions: Image morphometry successfully differentiates HGUC cases from benign non-neoplastic ones and might help to identify muscularis propria invasion in HGUC using a combination of nuclear parameters. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

15. The WHO system versus the Papanicolaou society of cytopathology system for reporting pancreaticobiliary cytology for risk stratification—which is better?

Author

Kundu, Reetu, primary, Kollabathula, Arpitha, additional, Gupta, Nalini, additional, Rohilla, Manish, additional, Rana, Surinder Singh, additional, Nada, Ritambhra, additional, Kalra, Naveen, additional, Basher, Rajender Kumar, additional, Gupta, Parikshaa, additional, Dey, Pranab, additional, Gupta, Rajesh, additional, Dutta, Usha, additional, and Srinivasan, Radhika, additional

Published
2023
Full Text
View/download PDF

16. Cytomorphologic and immunocytochemical characterization of pediatric pleuropulmonary blastoma with a comprehensive review of the literature

Author

Gupta, Parikshaa, primary, Chugh, Sanjoli, additional, Gupta, Nalini, additional, Gupta, Kirti, additional, Sodhi, Kushaljit Singh, additional, Kakkar, Nandita, additional, Srinivasan, Radhika, additional, Rohilla, Manish, additional, Kundu, Reetu, additional, Trehan, Amita, additional, Bansal, Deepak, additional, and Peters, Nitin James, additional

Published
2023
Full Text
View/download PDF

21. A COMPARATIVE STUDY TO ASSESS TISSUE ADEQUACY OF WET SUCTION VERSUS SLOW-PULL TECHNIQUE IN ENDOSCOPIC ULTRASOUND-GUIDED FINE NEEDLE BIOPSY IN SOLID LESIONS:A RANDOMISED CROSS OVER TRIAL

Author

Thakur, Rajneesh, primary, Samanta, Jayanta, additional, Gupta, Vikas, additional, Sinha, Saroj, additional, TANDUP, CHERRING, additional, SN, Satish, additional, rohilla, manish, additional, jearth, vaneet, additional, Mandavdhare, Harshal, additional, kumar, divyesh, additional, and Srinivasan, Radhika, additional

Published
2023
Full Text
View/download PDF

22. Mucormycosis: Cytomorphological spectrum in fine-needle aspiration cytology.

Author

Shastri, Malvika, Srinivasan, Radhika, Kundu, Reetu, Dey, Pranab, Gupta, Nalini, Gupta, Parikshaa, Rohilla, Manish, Kang, Mandeep, Kalra, Naveen, Kaur, Harsimran, and Rudramurthy, Shivaprakash

Subjects
CULTURE, RETROSPECTIVE studies, ACQUISITION of data, FUNGI, GRANULOMATOSIS with polyangiitis, MYCOSES, MEDICAL records, DESCRIPTIVE statistics, CYTOLOGY, NEEDLE biopsy
Abstract

Background: Mucormycosis is a fungal infection that can affect multiple organs. The role of fine-needle aspiration cytology (FNAC) in its diagnosis is not well documented. Aim: The objective of this study was to describe the detailed cytomorphologic features of mucormycosis on FNAC samples. Materials and Methods: A retrospective analysis of all cases diagnosed as mucormycosis on FNAC between January 2014 and July 2021 was performed for detailed cytomorphological evaluation and correlation to clinical data and microbiological studies wherever available. FNA was computed tomography-guided (n = 38), ultrasonography-guided (n = 31) or palpation-guided (n = 12), and slides were reviewed in two cases. Results: A total of 83 cases of mucormycosis were evaluated. An immunocompromised setting was observed in 48 cases. The most common site of FNA was the lung (n = 57) followed by liver, soft tissue, palate, mediastinum, orbital/ocular region, and lymph node. Isolated renal involvement, a unique feature, was seen in seven cases. The aspirates were necrotic to pus-like or blood-mixed particulate. Broad, nonseptate, foldable, ribbon-like fungal hyphae showing right-angled branching were seen. The tissue reaction was predominantly necro-inflammatory (n = 36), bland necrotic (n = 22), mixed inflammatory (n = 16), suppurative (n = 5), necrotizing granulomatous (n = 3), and granulomatous (n = 1). Immunocompromised patients showed mixed inflammatory responses more frequently. Fungal culture was positive for Rhizopus species in 2/13 cases and molecular testing in two additional cases corresponding to Rhizopus and Syncephalastrum spp. Conclusion: FNA provides quick and conclusive diagnosis of mucormycosis from varied anatomic sites enabling prompt institution of therapy. The tissue response is variable and to some extent dependent on the immune status of the patient. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

24. Randomized crossover trial of ‘Roll-over’ technique of abdominal paracentesis versus standard technique in suspected malignant ascites

Author

Jha, Daya Krishna, primary, Rohilla, Manish, additional, Das, Chandan K, additional, Irrinki, Santhosh, additional, Singh, Harjeet, additional, Arora, Aashima, additional, Saha, Subhas C, additional, Gupta, Pankaj, additional, Mandavdhare, Harshal S, additional, Dutta, Usha, additional, Sharma, Aman, additional, and Sharma, Vishal, additional

Published
2023
Full Text
View/download PDF

40. IDDF2022-ABS-0033 A randomized cross over study of rollover paracentesis with standard paracentesis is suspected malignant ascites

Author

Jha, Daya Krishna, primary, Rohilla, Manish, additional, Das, Chandan K, additional, Singh, Harjeet, additional, Irrinki, Santosh, additional, Arora, Aashima, additional, Saha, Subhas C, additional, Gupta, Pankaj, additional, Mandavdhare, Harshal S, additional, Dutta, Usha, additional, Sharma, Aman, additional, and Sharma, Vishal, additional

Published
2022
Full Text
View/download PDF

47. Metastatic germ cell tumour in effusion cytology

Author

Saini, Tarunpreet, primary, Kundu, Reetu, additional, Rastogi, Pulkit, additional, Rohilla, Manish, additional, Gupta, Parikshaa, additional, Gupta, Nalini, additional, Srinivasan, Radhika, additional, and Dey, Pranab, additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results