Search

Your search keyword '"Ronchetto P"' showing total 100 results
Start Over Author "Ronchetto P"
100 results on '"Ronchetto P"'

6. Using the Looking Glass at the International Center for Public Enterprises in Slovenia: Implications for Teaching Interpersonal Skills and Introducing International Business Concepts.

Author

Ronchetto, John and Johnston, Wesley

Abstract

A study assessed the effectiveness of a business administration simulation exercise designed to train students in problem solving, decision making, and interpersonal skills. Results of the simulation in a Slovenian institution with graduate students in international business are discussed, along with implications for incorporating the exercise into managerial training within companies competing in a global market. (MSE)

Published
1995

19. Hiv, povertà e disuguaglianze Scenari epidemiologici e sociali di una pandemia asimmetrica.

Author

Ronchetto, Martina and Ronchetto, Flavio

Abstract

HIV is a global scourge, but with polarization in poorest countries, mainly of sub-Saharan Africa. This observation is the basis of inclusion of HIV/AIDS in the group of "Infectious Diseases of Poverty". However, recent studies have shown that it is not poverty that drives "directly" the HIV epidemic, but income inequality and gender, and other social, political and cultural mediators, acting influencing individual sexual behavior. In this paper, the authors considered the results of empirical (quantitative and statistical) studies of association between HIV and macro-social phenomena. At the same time, they emphasize the need to identify the mechanisms and processes, that is the real causes, of this link. They take into a particular consideration the sociological research lines addressed to open the black box of these causal mechanisms. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

21. Genetic history of cystic fibrosis mutations in Italy. I. Regional distribution

Author

Rendine, S, Calafell, F, Cappello, N, Gagliardini, R, Caramia, G, Rigillo, N, Silvetti, M, Zanda, M, Miano, A, Battistini, F, Marianelli, L, Taccetti, G, Diana, M, Romano, L, Romano, C, Giunta, A, Padoan, R, Pianaroli, A, Raia, V, De Ritis, G, Battistini, A, Grzincich, G, Japichino, L, Pardo, F, Antonelli, M, Quattrucci, S, Lucidi, V, Castro, M, Santini, B, Castello, M, Guanti, G, Leoni, G, Cao, A, Toffoli, C, Lucci, E, Vullo, C, Torricelli, F, Sbernini, F, Romeo, G, Ronchetto, P, Seia, M, Rossi, A, Ferrari, M, Cremonesi, L, Salvatore, L, Castaldo, G, D'Alcamo, E, Maggio, A, Sangiuolo, Fc, Dallapiccola, B, Maceratesi, P, Bisceglia, L, Gasparini, P, Carbonara, A, Bonizzato, A, Cabrini, G, Bombieri, C, Pignatti, P, Borgo, G, Castellani, C, Villani, A, Arduino, C, Salvatore, D, Mastella, G, Piazza, A, Rendine, S, Calafell, F, Cappello, N, Gagliardini, R, Caramia, G, Rigillo, N, Silvetti, M, Zanda, M, Miano, A, Battistini, F, Marianelli, L, Taccetti, G, Diana, Mc, Romano, L, Romano, C, Giunta, A, Padoan, R, Pianaroli, A, Raia, Valeria, DE RITIS, G, Battistini, A, Grzincich, G, Japichino, L, Pardo, F, Piazza, A., Rendine, S., Calafell, F., Salvatore, F., and Castaldo, Giuseppe

Subjects
Cystic Fibrosis, Population, Statistical, major clinical study, Factor Analysis, Statistical, Gene Frequency, Humans, Italy, Phylogeny, Genetics, Population, Mutation, Settore MED/03 - Genetica Medica, geographic distribution, Genetics, gene mutation, human, cystic fibrosis, gene frequency, gene mutation, geographic distribution, human, italy, major clinical study, Factor Analysis, Genetics (clinical)
Abstract

Earlier analysis of the Italian population showed patterns of genetic differentiation that were interpreted as being the result of population settlements going back to pre-Roman times. DNA disease mutations may be a powerful tool in further testing this hypothesis since the analysis of diseased individuals can detect variants too rare to be resolved in normal individuals. We present data on the relative frequencies of 60 cystic fibrosis (CF) mutations in Italy and the geographical distribution of the 12 most frequent CF mutations screened in 3492 CF chromosomes originating in 13 Italian regions. The 12 most frequent mutations characterize about 73% of the Italian CF chromosomes. The most common mutation, delta F508, has an average frequency of 51%, followed by N1303K and G542X, both with average frequencies around 5%. Multivariate analyses show that the relative frequencies of CF mutations are heterogeneous among Italian regions, and that this heterogeneity is weakly correlated with the geographical pattern of non-DNA 'classical' genetic markers. The northern regions are well differentiated from the central-southern regions and within the former group the western and eastern regions are remarkably distinct. Moreover, Sardinia shows the presence of mutation T338I, which seems absent in any other European CF chromosome. The north-western regions of Italy, characterized by the mutation 1717-1G--A, were under Celtic influence, while the north-east regions, characterized by the mutations R1162X, 2183AA--G and 711 + 5G--A, were under the influence of the Venetic culture.

Published
1997

22. No Evidence for Segregation Distortion of Cystic Fibrosis Alleles among Sibs of Cystic Fibrosis Patients

Author

Devoto, M, Romeo, G, ten Kate, L P, Chevalier, F, Bozon, D, Estivill, X, Casals, T, Abeliovich, D, Lerer, I, Padoan, R, Seia, M, Hill, A, Liechtigallati, S, Kramer, R, Beards, F, DEAR, S, DALLAPICCOLA, B, SANGIUOLO, F, MACEK, M, MCMAHON, R, CONNARTY, M, HARVEY, JF, CLAUSTRES, M, DESGEORGES, M, de Vries, R, Scheffer, H, CANKIKLAIN, N, AUDREZET, MP, BIENVENU, T, CHOMEL, JC, DZIADEK, [No Value], TUMMLER, B, SCHWARZ, M, HAWORTH, A, BENITEZ, J, MAZURCZAK, T, BAL, J, CREMONESI, L, RONCHETTO, P, CASHMAN, SM, FEREC, C, CUPPENS, H, Bauer, I, ANGELICHEVA, D, WAGNER, K, PACHECO, P, BONIZZATO, A, MCMAHON, CJ, RAVNIKGLAVAC, M, REIS, A, STUHRMANN, M, GARNERONE, S, CURTIS, A, GRUNING, G, KANAVAKIS, E, KLAASSEN, T, GRADE, T, and Witt, Michal

Subjects
Pathology, medicine.medical_specialty, business.industry, Distortion, Genetics, medicine, Allele, medicine.disease, business, Cystic fibrosis, Genetics (clinical)
Published
1995

25. DNA polymorphisms and conditions for SSCP analysis of the 20 exons of the RET proto-oncogene

Author

Ceccherini, I., Hofstra, R. M. W., Luo, Y., Stulp, R. P., Barone, V., Stelwagen, T., Bocciardi, R., Nijveen, H., Bolino, A., Marco Seri, Ronchetto, P., Pasini, B., Bozzano, M., Buys, C. H. C. M., and Romeo, G.

Subjects
RET proto-oncogene, MISMATCHES, LINE, multiple endocrine neoplasia, POINT MUTATIONS, PROTOONCOGENE, SINGLE BASE SUBSTITUTIONS
Abstract

Recently identified mutations affecting different domains of the RET proto-oncogene are associated with Multiple Endocrine Neoplasia type 2A (MEN 2A) and type 2B (MEN 2B), familial and sporadic Medullary Thyroid Carcinomas (MTC) and Hirschsprung disease (HSCR). In order to facilitate the screening for RET mutations, and to study possible genotype-phenotype correlations, we established exon-intron junctions and extended the intronic sequences flanking the 20 exons of this gene. This made it possible to design primers and to develop PCR conditions useful for SSCP analysis of the whole RET coding sequence. Nine conformational variants were observed which after sequencing turned out to be 8 silent mutations and a conservative amino acid substitution. Restriction analysis performed on DNA samples from unrelated controls confirmed the polymorphic nature of six of these nucleotide changes and made it possible to estimate the frequency of the corresponding alleles.

Published
1994

30. Analysis of delta F508 does not confirm a previously reported recombination in a cystic fibrosis family

Author

Devoto, Marcella, Ronchetto, P., Romano, L., and Romeo, G.

Subjects
Genetic Markers, Recombination, Genetic, Letter, Cystic Fibrosis, Genetic Linkage, Restriction Mapping, Wnt1 Protein, Zebrafish Proteins, Proto-Oncogene Mas, Wnt2 Protein, Wnt Proteins, Proto-Oncogene Proteins, Humans, Polymorphism, Restriction Fragment Length
Abstract

A candidate gene for cystic fibrosis was recently isolated by selective cloning of HpaII-tiny-fragment islands; it maps considerably closer to CF than does MET or D7S8 (pJ3.11), and DNA polymorphisms from this region are in marked disequilibrium with CF. cDNA cloning has shown that this protein has a growth factor-like structure and shows homology to the murine and human proto-oncogene int-1; it is designated IRP (int-1-related protein). DNA sequences from the IRP locus that recognize RFLPs are proving to be highly informative for prenatal diagnosis. We report five crossovers that have been identified which occur either within the IRP locus or between IRP and CF; these recombinants demonstrate that CF maps between the DNA markers D7S8 and KM.19.

Published
1990

32. Genetic history of cystic fibrosis mutations in Italy. I. Regional distribution

Author

RENDINE, S., primary, CALAFELL, F., additional, CAPPELLO, N., additional, GAGLIARDINI, R., additional, CARAMIA, G., additional, RIGILLO, N., additional, SILVETTI, M., additional, ZANDA, M., additional, MIANO, A., additional, BATTISTINI, F., additional, MARIANELLI, L., additional, TACCETTI, G., additional, DIANA, M. C., additional, ROMANO, L., additional, ROMANO, C., additional, GIUNTA, A., additional, PADOAN, R., additional, PIANAROLI, A., additional, RAIA, V., additional, DE RITIS, G., additional, BATTISTINI, A., additional, GRZINCICH, G., additional, JAPICHINO, L., additional, PARDO, F., additional, ANTONELLI, M., additional, QUATTRUCCI, S., additional, LUCIDI, V., additional, CASTRO, M., additional, SANTINI, B., additional, CASTELLO, M., additional, GUANTI, G., additional, LEONI, G. B., additional, CAO, A., additional, TOFFOLI, C., additional, LUCCI, E., additional, VULLO, C., additional, TORRICELLI, F., additional, SBERNINI, F., additional, ROMEO, G., additional, RONCHETTO, P., additional, SEIA, M., additional, ROSSI, A., additional, FERRARI, M., additional, CREMONESI, L., additional, SALVATORE, F., additional, CASTALDO, G., additional, D'ALCAMO, E., additional, MAGGIO, A., additional, SANGIUOLO, F., additional, DALLAPICCOLA, B., additional, MACERATESI, P., additional, BISCEGLIA, L., additional, GASPARINI, P., additional, CARBONARA, A., additional, BONIZZATO, A., additional, CABRINI, G., additional, BOMBIERI, C., additional, PIGNATTI, P. F., additional, BORGO, G., additional, CASTELLANI, C., additional, VILLANI, A., additional, ARDUINO, C., additional, SALVATORE, D., additional, MASTELLA, G., additional, and PIAZZA, A., additional

Published
1997
Full Text
View/download PDF

34. Using the Looking Glass at the International Center for Public Enterprises in Slovenia

Author

Ronchetto, John

Abstract

This article presenrs justification for using experiential exercises, in particular the Looking Glass behavioral simulation to apply selected analytical and interpersonal concepts. General procedures used for introducing, running, and debriefing the simulation are reviewed. Results of a simulation run at the International Center for Public Enterprises in Ljubljana, Slovenia, with international MBA studenls are reported. Implications for incorporating the ffiI exercise into the training of managers in organizations competing in global markets are noted.

Published
1996
Full Text
View/download PDF

48. Microarray based analysis of an inherited terminal 3p26.3 deletion, containing only the CHL1 gene, from a normal father to his two affected children

Author

Lerone Margherita, Divizia Maria, Béna Frédérique, Gimelli Stefania, Ronchetto Patrizia, Cuoco Cristina, Mirabelli-Badenier Marisol, Mascaretti Monica, and Gimelli Giorgio

Subjects
Medicine
Abstract

Abstract Background terminal deletions of the distal portion of the short arm of chromosome 3 cause a rare contiguous gene disorder characterized by growth retardation, developmental delay, mental retardation, dysmorphisms, microcephaly and ptosis. The phenotype of individuals with deletions varies from normal to severe. It was suggested that a 1,5 Mb minimal terminal deletion including the two genes CRBN and CNTN4 is sufficient to cause the syndrome. In addition the CHL1 gene, mapping at 3p26.3 distally to CRBN and CNTN4, was proposed as candidate gene for a non specific mental retardation because of its high level of expression in the brain. Methods and Results we describe two affected siblings in which array-CGH analysis disclosed an identical discontinuous terminal 3p26.3 deletion spanning less than 1 Mb. The deletion was transmitted from their normal father and included only the CHL1 gene. The two brothers present microcephaly, light mental retardation, learning and language difficulties but not the typical phenotype manifestations described in 3p- syndrome. Conclusion a terminal 3p26.3 deletion including only the CHL1 gene is a very rare finding previously reported only in one family. The phenotype of the affected individuals in the two families is very similar and the deletion has been inherited from an apparently normal parent. As already described for others recurrent syndromes with variable phenotype, these findings are challenging in genetic counselling because of an evident variable penetrance.

Published
2011
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results