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4. Shunt Infection

Author

Linares, Jorge, Iglesias, Sara, Ros, Bienvenido, Alexiou, Georgios, editor, and Prodromou, Neofytos, editor

Published
2022
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14. List of Contributors

Author

Abd-El-Barr, Muhammad M., primary, Agarwal, Vijay, additional, Albuquerque, Felipe C., additional, Aliabadi, Hamidreza, additional, Al-Khalili, Yasir, additional, Almefty, Rami O., additional, Amin-Hanjani, Sepideh, additional, Angileri, Filippo F., additional, Arraez, Cinta, additional, Arraez, Miguel A., additional, Baranoski, Jacob F., additional, Barrow, Daniel L., additional, Bendok, Bernard R., additional, Benzel, Edward C., additional, Berger, Mitchel S., additional, Bhagavatula, Indira Devi, additional, Bhat, Dhananjaya I., additional, Bilsky, Mark, additional, Binning, Mandy J., additional, Boop, Frederick A., additional, Bramall, Alexa N., additional, Bruce, Jeffrey N., additional, Buchholz, Avery L., additional, Burchiel, Kim J., additional, Burkhardt, Jan-Karl, additional, Cardali, Salvatore M., additional, Chang, Hsuan-Kan, additional, Charbel, Fady T., additional, Chen, Yi-Ren, additional, Chuang, Jimmy Ming-Jung, additional, Cohen, Alan R., additional, Conti, Alfredo, additional, Corliss, Brian M., additional, D'Amico, Randy S., additional, Daniel, Roy Thomas, additional, DeCarvalho, Stephanie A., additional, Digiorgio, Anthony M., additional, Fargen, Kyle M., additional, Fehlings, Michael G., additional, Fernandez-Miranda, Juan C., additional, Flores, Bruno C., additional, Fridley, Jared, additional, Friedman, Allan, additional, Galgano, Michael A., additional, Ganau, Mario, additional, Gardner, Paul A., additional, Germanò, Antonino F., additional, Ghobrial, George M., additional, Gibani, Siraj, additional, Gillick, John L., additional, Gokaslan, Ziya L., additional, Gooch, M. Reid, additional, Grant, Gerald A., additional, Grassia, Fabio, additional, Groff, Michael W., additional, Grossbach, Andrew J., additional, Harrop, James S., additional, Heary, Robert F., additional, Hedayat, Hirad S., additional, Heilman, Carl B., additional, Heller, Robert S., additional, Fennell, Vernard S., additional, Hervey-Jumper, Shawn L., additional, Hoh, Brian L., additional, Howard, Brian M., additional, Hughes, Joshua D., additional, Hussain, Ibrahim, additional, Iaccarino, Corrado, additional, Iqbal, M. Omar, additional, Jabarkheel, Rashad, additional, Josiah, Darnell T., additional, Kalakoti, Piyush, additional, Keen, Joseph R., additional, Kemp, William J., additional, Kim, Irene, additional, Kura, Bhavani, additional, La Torre, Domenico, additional, Lang, Michael J., additional, Laufer, Ilya, additional, Lawton, Michael T., additional, Levy, Elad I., additional, Link, Michael J., additional, Lo, William B., additional, Lunsford, L. Dade, additional, Maduri, Rodolfo, additional, Magown, Philippe, additional, Maiti, Tanmoy Kumar, additional, Mansfield, Kevin, additional, Nasser, Mohammed, additional, Monaco, Edward, additional, Mummaneni, Praveen V., additional, Narayan, Vinayak, additional, Niranjan, Ajay, additional, Oakes, W. Jerry, additional, Ojemann, Jeff, additional, Oyesiku, Nelson M., additional, Pabaney, Aqueel, additional, Patra, Devi Prasad, additional, Pollock, Bruce E., additional, Quinn, John C., additional, Ratliff, John K., additional, Rehder, Roberta, additional, Rekito, Andy, additional, Resnick, Daniel K., additional, Ros, Bienvenido, additional, Rosenfeld, Jeffrey V., additional, Rosenwasser, Robert H., additional, Rutka, James T., additional, Sabourin, Victor, additional, Sampson, John H., additional, Sattur, Mithun G., additional, Savardekar, Amey R., additional, Servadei, Franco, additional, Shaffrey, Christopher I., additional, Shakur, Sophia F., additional, Snyderman, Carl H., additional, Soliman, Hesham, additional, Spetzler, Robert F., additional, Spinner, Robert J., additional, Stadler, James A., additional, Sun, Hai, additional, Tee, Jin W., additional, Tenorio, Alexander, additional, Tomasello, Francesco, additional, Traynelis, Vincent C., additional, Veznedaroglu, Erol, additional, Viaroli, Edoardo, additional, Virk, Michael S., additional, Wang, Eric W., additional, Wang, Michael Y., additional, Welz, Matthew E., additional, West, James L., additional, Wilson, John A., additional, Wilson, Thomas J., additional, Winkler, Ethan A., additional, and Wolfe, Stacey Quintero, additional

Published
2019
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20. Increased levels of tumour necrosis factor alpha (TNFα) but not transforming growth factor-beta 1 (TGFβ1) are associated with the severity of congenital hydrocephalus in the hyh mouse

Author

Jiménez, Antonio-Jesús, Rodríguez-Pérez, Luis-Manuel, Domínguez-Pinos, María-Dolores, Gómez-Roldán, María-Carmen, García-Bonilla, María, Ho-Plagaro, Ailec, Roales-Buján, Ruth, Jiménez, Sebastián, Roquero-Mañueco, María-Carmen, Martínez-León, María-Isabel, García-Martín, María-Luisa, Cifuentes, Manuel, Ros, Bienvenido, Arráez, Miguel-Ángel, Vitorica, Javier, Gutiérrez, Antonia, and Pérez-Fígares, José-Manuel

Published
2014
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26. Colaboradores

Author

Abd-El-Barr, Muhammad M., Agarwal, Vijay, Albuquerque, Felipe C., Aliabadi, Hamidreza, Al-Khalili, Yasir, Almefty, Rami O., Amin-Hanjani, Sepideh, Angileri, Filippo F., Arraez, Cinta, Arraez, Miguel A., Baranoski, Jacob F., Barrow, Daniel L., Bendok, Bernard R., Benzel, Edward C., Berger, Mitchel S., Bhagavatula, Indira Devi, Bhat, Dhananjaya I., Bilsky, Mark, Binning, Mandy J., Boop, Frederick A., Bramall, Alexa N., Bruce, Jeffrey N., Buchholz, Avery L., Burchiel, Kim J., Burkhardt, Jan-Karl, Cardali, Salvatore M., Chang, Hsuan-Kan, Charbel, Fady T., Chen, Yi-Ren, Chuang, Jimmy Ming-Jung, Cohen, Alan R., Conti, Alfredo, Corliss, Brian M., D’Amico, Randy S., Daniel, Roy Thomas, DeCarvalho, Stephanie A., Digiorgio, Anthony M., Fargen, Kyle M., Fehlings, Michael G., Fernandez-Miranda, Juan C., Flores, Bruno C., Fridley, Jared, Friedman, Allan, Galgano, Michael A., Ganau, Mario, Gardner, Paul A., Germanò, Antonino F., Ghobrial, George M., Gibani, Siraj, Gillick, John L., Gokaslan, Ziya L., Gooch, M. Reid, Grant, Gerald A., Grassia, Fabio, Groff, Michael W., Grossbach, Andrew J., Harrop, James S., Heary, Robert F., Hedayat, Hirad S., Heilman, Carl B., Heller, Robert S., Fennell, Vernard S., Hervey-Jumper, Shawn L., Hoh, Brian L., Howard, Brian M., Hughes, Joshua D., Hussain, Ibrahim, Iaccarino, Corrado, Iqbal, M. Omar, Jabarkheel, Rashad, Josiah, Darnell T., Kalakoti, Piyush, Keen, Joseph R., Kemp, William J., Kim, Irene, Kura, Bhavani, La Torre, Domenico, Lang, Michael J., Laufer, Ilya, Lawton, Michael T., Levy, Elad I., Link, Michael J., Lo, William B., Lunsford, L. Dade, Maduri, Rodolfo, Magown, Philippe, Maiti, Tanmoy Kumar, Mansfield, Kevin, Monaco, Edward, III, Mummaneni, Praveen V., Narayan, Vinayak, Nasser, Mohammed, Niranjan, Ajay, Oakes, W. Jerry, Ojemann, Jeff, Oyesiku, Nelson M., Pabaney, Aqueel, Patra, Devi Prasad, Pollock, Bruce E., Quinn, John C., Ratliff, John K., Rehder, Roberta, Rekito, Andy, Resnick, Daniel K., Ros, Bienvenido, Rosenfeld, Jeffrey V., Rosenwasser, Robert H., Rutka, James T., Sabourin, Victor, Sampson, John H., Sattur, Mithun G., Savardekar, Amey R., Servadei, Franco, Shaffrey, Christopher I., Shakur, Sophia F., Snyderman, Carl H., Soliman, Hesham, Spetzler, Robert F., Spinner, Robert J., Stadler, James A., III, Sun, Hai, Tee, Jin W., Tenorio, Alexander, Tomasello, Francesco, Traynelis, Vincent C., Veznedaroglu, Erol, Viaroli, Edoardo, Virk, Michael S., Wang, Eric W., Wang, Michael Y., Welz, Matthew E., West, James L., Wilson, John A., Wilson, Thomas J., Winkler, Ethan A., and Wolfe, Stacey Quintero

Published
2020
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32. Factors related to shunt survival in paediatric hydrocephalus. Could failure be avoided?

Author

Iglesias S, Ros B, Martín Á, Carrasco A, Segura M, Ros A, Rius F, and Arráez MÁ

Subjects
Adolescent, Antibiotic Prophylaxis methods, Child, Child, Preschool, Equipment Design, Female, Humans, Hydrocephalus complications, Hydrodynamics, Infant, Infant, Newborn, Male, Meningitis complications, Postoperative Complications epidemiology, Postoperative Complications etiology, Postoperative Complications prevention & control, Proportional Hazards Models, Prosthesis-Related Infections epidemiology, Prosthesis-Related Infections etiology, Prosthesis-Related Infections prevention & control, Reoperation, Retrospective Studies, Risk Factors, Ventriculoperitoneal Shunt adverse effects, Cerebrospinal Fluid Shunts adverse effects, Equipment Failure, Hydrocephalus surgery
Abstract

Background: Improved shunt survival and a better understanding of factors related to failure in paediatric hydrocephalus still pose a challenge for neurosurgeons, in order to avoid morbidity and mortality, as well as the economic impact of repeated revision surgeries. For these reasons, an analysis is performed on the factors related to the first shunt failure in the long-term follow-up of a series in a single centre., Methods: A retrospective review was conducted on 166 hydrocephalic paediatric patients shunted for the first time between 2000 and 2014. An analysis was made of the statistical relationships between first shunt failure and the demographic, aetiological, surgical and clinical variables., Results: Of the 166 shunts implanted in our centre during the study period, 111 required revision over a mean follow-up period of 93 months. Factors significantly related to failure were post-haemorrhagic and post-infectious hydrocephalus, meningitis episode, posterior burr hole, differential pressure valve, standard catheter in first surgery, and symptomatic over-drainage. Multivariable analysis showed that previous meningitis and symptomatic over-drainage were risk factors for shunt failure, whereas frontal burr hole location and antibiotic-impregnated catheters were protective factors. Cox regression determined that independent factors significantly related to a worse shunt survival, were shunt infection and symptomatic over-drainage., Conclusions: Meningitis, symptomatic over-drainage, frontal burr hole, and antibiotic impregnated catheters are significant prognostic factors for shunt survival. Shunt infection and symptomatic over-drainage are independent factors significantly related to a shorter shunt survival. Prospective, randomised, controlled trials are required to validate these results., (Copyright © 2017 Sociedad Española de Neurocirugía. Publicado por Elsevier España, S.L.U. All rights reserved.)

Published
2017
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33. [Factors related to endoscopic third ventriculostomy prognosis in the paediatric population].

Author

Iglesias S, Ros B, Ibáñez G, Dominguez M, Medina JM, and Arráez MÁ

Subjects
Age Factors, Brain Neoplasms complications, Child, Humans, Hydrocephalus complications, Hydrocephalus etiology, Kaplan-Meier Estimate, Meningomyelocele complications, Prognosis, Retrospective Studies, Treatment Outcome, Ventriculoperitoneal Shunt, Endoscopy, Hydrocephalus surgery, Third Ventricle surgery, Ventriculostomy
Abstract

Endoscopic third ventriculostomy (ETV) for paediatric patients has different success rates between the published series, making its recommendation controversial. Different definitions of ETV success, hydrocephalus aetiology or patient age at diagnosis may influence the outcome of the ETV procedure. The aim of this work was to analyse our clinical series and to examine the influence of different factors on ETV outcome. This was a retrospective study of 45 patients who had undergone ETV at our Paediatric Hospital between 2003 and 2009. Successful outcome was defined as a combination of features including clinical improvement or stability, with at least 1 positive radiological parameter. The influence of age, hydrocephalus aetiology, existence or not of previous shunt and the type of endoscopic procedure were analysed in relation to ETV outcome. Up to 29% of patients were younger than 1 year. The most frequent causes of hydrocephalus were: brain tumour, aqueductal stenosis and myelomeningocele. The overall success rate was 69%, with a mean follow-up period of 26 months and mean ETV survival of 14 months. We obtained statistically significant differences in ETV success between patients aged over and under 6 moths. Our ETV success rate can be considered safe and effective for the treatment of paediatric hydrocephalus. To our knowledge, ETV is most effective in patients aged 6 months and over., (Copyright © 2012 Sociedad Española de Neurocirugía. Published by Elsevier España. All rights reserved.)

Published
2013
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