Search

Your search keyword '"Rossi,Giovanni"' showing total 3,218 results
Start Over Author "Rossi,Giovanni"
3,218 results on '"Rossi,Giovanni"'

2. Extracellular vesicles miR-574-5p and miR-181a-5p as prognostic markers in NSCLC patients treated with nivolumab

Author

Genova, Carlo, Marconi, Silvia, Chiorino, Giovanna, Guana, Francesca, Ostano, Paola, Santamaria, Sara, Rossi, Giovanni, Vanni, Irene, Longo, Luca, Tagliamento, Marco, Zullo, Lodovica, Dal Bello, Maria Giovanna, Dellepiane, Chiara, Alama, Angela, Rijavec, Erika, Ludovini, Vienna, Barletta, Giulia, Passiglia, Francesco, Metro, Giulio, Baglivo, Sara, Chiari, Rita, Rivoltini, Licia, Biello, Federica, Baraibar, Iosune, Gil-Bazo, Ignacio, Novello, Silvia, Grossi, Francesco, and Coco, Simona

Published
2024
Full Text
View/download PDF

7. Proximal sealing in the aortic arch for inner curve disease using the custom Relay scalloped and fenestrated stent graft

Author

Alberti, Antonino, Buia, Francesco, Di Marco, Luca, Massara, Mafalda, Bonanno, Paolo, Lepidi, Sandro, Berti, Sergio, Sica, Simona, Pratesi, Giovanni, Rossi, Giovanni, Ferraresi, Marco, Lovato, Luigi, Volpe, Pietro, Fadda, Gian Franco, Ferri, Michelangelo, Rizza, Antonio, D'Oria, Mario, Micheli, Raimondo, Tshomba, Yamume, and Tinelli, Giovanni

Published
2024
Full Text
View/download PDF

8. Outcomes of off-the-shelf preloaded inner branch device for urgent endovascular thoraco-abdominal aortic repair in the ItaliaN Branched Registry of E-nside EnDograft

Author

Antonello, Michele, Piazza, Michele, Squizzato, Francesco, Spezia, Matteo, Grego, Franco, Pratesi, Giovanni, Spinella, Giovanni, Esposito, Davide, Bastianon, Martina, Tshomba, Yamume, Donati, Tommaso, Sica, Simona, Tinelli, Giovanni, Ferri, Michelangelo, Quaglino, Simone, Gaggiano, Andrea, Vento, Vincenzo, Carbonari, Luciano, Gatta, Emanuele, Lenti, Massimo, Simonte, Gioele, Isernia, Giacomo, Parlani, Giambattista, Piffaretti, Gabriele, Frigatti, Paolo, Scrivere, Paola, Furlan, Federico, Veraldi, Gian Franco, Mezzetto, Luca, Gennai, Stefano, Leone, Nicola, Silingardi, Roberto, Iacono, Gustavo, Turricchia, Giorgio Ubaldo, Angiletta, Domenico, Maione, Massimo, Apostolou, Dimitri, Pulli, Raffaele, Fargion, Aaron, Filippi, Federico, De Angelis, Filippo, Arici, Vittorio, Bozzani, Antonio, Luigi Molinari, Alessandro Carlo, Rossi, Giovanni, Costantini Brancadoro, Emidio, Ferraris, Matteo, Dorrucci, Vittorio, Derone, Graziana, Tolva, Valerio Stefano, Compagnoni, Nicola Monzio, Segramora, Vittorio Maria, Deleo, Gaetano, Bracale, Umberto, Guzzardi, Giuseppe, Ferrer, Ciro, Giudice, Rocco, Sbarigia, Enrico, Cuozzo, Simone, Gattuso, Roberto, Mansour, Wassim, Di Marzo, Luca, Grimaldi, Sabrina, Corona, Mario, Chisci, Emiliano, Mechelagnoli, Stefano, De Donato, Gianmarco, Palasciano, Giancarlo, Pasqui, Edoardo, Candeloro, Laura, Ricci, Carmelo, Neri, Eugenio, Mangialardi, Nicola, Orrico, Matteo, Ronchey, Sonia, Fazzini, Stefano, Ippoliti, Arnaldo, Discalzi, Andrea, Rossato, Denis, Vio, Elias, Galeazzi, Edoardo, Farneti, Fabrizio, Bertoglio, Luca, Volpe, Pietro, Massara, Mafalda, Milite, Domenico, and Xodo, Andrea

Published
2024
Full Text
View/download PDF

11. Analysis of Hospital Admissions of Neurological Patients in the COVID-19 Era: Comparison Between Hospitals

Author

Montella, Emma, Marino, Marta Rosaria, Giglio, Cristiana, Raiola, Eliana, Russo, Giuseppe, Rossi, Giovanni, Borrelli, Anna, Triassi, Maria, Scala, Arianna, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Wen, Shiping, editor, and Yang, Cihui, editor

Published
2023
Full Text
View/download PDF

12. Impact of COVID-19 in a Surgery Department: Comparison Between Two Italian Hospitals

Author

Trunfio, Teresa Angela, Marino, Marta Rosaria, Giglio, Cristiana, Majolo, Massimo, Longo, Giuseppe, Basso, Morena Anna, Rossi, Giovanni, Borrelli, Anna, Triassi, Maria, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Wen, Shiping, editor, and Yang, Cihui, editor

Published
2023
Full Text
View/download PDF

13. Predictive Algorithms to Study the Hospitalization for Knee Replacement Surgery: A Bicentric Study

Author

Ponsiglione, Alfonso Maria, Marino, Marta Rosaria, Raiola, Eliana, Russo, Giuseppe, Balato, Giovanni, Festa, Enrico, Rossi, Giovanni, Borrelli, Anna, Triassi, Maria, Romano, Maria, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Wen, Shiping, editor, and Yang, Cihui, editor

Published
2023
Full Text
View/download PDF

14. Covid-19: The Effect on Hospitalization Patient of Ophthalmology Department in 'Antonio Cardarelli' Hospital

Author

Montella, Emma, Marino, Marta Rosaria, Raiola, Eliana, Majolo, Massimo, Russo, Giuseppe, Rossi, Giovanni, Borrelli, Anna, Triassi, Maria, Scala, Arianna, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Wen, Shiping, editor, and Yang, Cihui, editor

Published
2023
Full Text
View/download PDF

15. Use of Statistical Analysis to Evaluate How Covid-19 Has Changed the Management of the Neurosurgery Department of the AORN 'A. Cardarelli' in Naples

Author

Scala, Arianna, Marino, Marta Rosaria, Giglio, Cristiana, Raiola, Eliana, Russo, Giuseppe, Basso, Morena Anna, Rossi, Giovanni, Borrelli, Anna, Triassi, Maria, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Wen, Shiping, editor, and Yang, Cihui, editor

Published
2023
Full Text
View/download PDF

16. Modeling LOS After Percutaneous Valvuloplasty: A Bicentric Study

Author

Montella, Emma, Marino, Marta Rosaria, Majolo, Massimo, Raiola, Eliana, Russo, Giuseppe, Longo, Giuseppe, Rossi, Giovanni, Borrelli, Anna, Triassi, Maria, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Wen, Shiping, editor, and Yang, Cihui, editor

Published
2023
Full Text
View/download PDF

17. Multiple Regression Model to Analyze the Length of Stay for Patients Undergoing Laparoscopic Appendectomy: A Bicentric Study

Author

Montella, Emma, Marino, Marta Rosaria, Frangiosa, Alessandro, Mazia, Giuseppe, Majolo, Massimo, Raiola, Eliana, Russo, Giuseppe, Longo, Giuseppe, Rossi, Giovanni, Borrelli, Anna, Triassi, Maria, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Wen, Shiping, editor, and Yang, Cihui, editor

Published
2023
Full Text
View/download PDF

19. Uncomplicated Type B Aortic Dissection: A European Multicentre Cross-Sectional Evaluation

Author

Bashir, Mohamad, Jubouri, Matti, Surkhi, Abdelaziz O., Williams, Ian M., Davidovic, Lazar B., Koncar, Igor, Baltrūnas, Tomas, Kunt, Aysegul, Tanyeli, Ömer, Bayram, Muhammed, Ugur, Murat, Rossi, Giovanni, Stelzmueller, Marie-Elisabeth, Hoksbergen, Arjan W.J., Jongkind, Vincent, Bertoglio, Luca, Zacà, Sergio, Mansour, Wassim, Sirignano, Pasqualino, D'Oria, Mario, Tolva, Valerio Stefano, Van Herzeele, Isabelle, Klincheva, Milka, Atanasov, Zvonka, Bartoli, Stefano, Bellosta, Raffaello, Chisci, Emiliano, Guagliano, Alberto, Teraa, Martin, Ivak, Peter, Recicarova, Sandra, Pellenc, Quentin, Heijmen, Robin, Pfister, Karin, Piffaretti, Gabriele, Hutchings, Hayley, Holland, Gail, Bailey, Damian M., Thielmann, Matthias, and Jakob, Heinz

Published
2024
Full Text
View/download PDF

20. Front-line liquid biopsy for early molecular assessment and treatment of hospitalized lung cancer patients

Author

Parisi, Francesca, De Luca, Giuseppa, Mosconi, Manuela, Lastraioli, Sonia, Dellepiane, Chiara, Rossi, Giovanni, Puglisi, Silvia, Bennicelli, Elisa, Barletta, Giulia, Zullo, Lodovica, Santamaria, Sara, Mora, Marco, Ballestrero, Alberto, Montecucco, Fabrizio, Bellodi, Andrea, Del Mastro, Lucia, Lambertini, Matteo, Barisione, Emanuela, Cittadini, Giuseppe, Tagliabue, Elena, Spagnolo, Francesco, Tagliamento, Marco, Coco, Simona, Dono, Mariella, and Genova, Carlo

Published
2024
Full Text
View/download PDF

21. Diagnosis of lung cancer following emergency admission: Examining care pathways, clinical outcomes, and advanced NSCLC treatment in an Italian cancer Center

Author

Vallome, Giacomo, Cafaro, Iacopo, Bottini, Annarita, Dellepiane, Chiara, Rossi, Giovanni, Bennicelli, Elisa, Parisi, Francesca, Zullo, Lodovica, Tagliamento, Marco, Ballestrero, Alberto, Barisione, Emanuela, Grazia Piroddi, Ines Maria, Montecucco, Fabrizio, Carbone, Federico, Pronzato, Paolo, Lambertini, Matteo, Spagnolo, Francesco, Barletta, Giulia, Barcellini, Lucrezia, Ferrante, Michele, Nardin, Simone, Coco, Simona, Marconi, Silvia, Zinoli, Linda, Moscatelli, Paolo, Arboscello, Eleonora, Del Mastro, Lucia, Bellodi, Andrea, and Genova, Carlo

Published
2023
Full Text
View/download PDF

23. NEUROCISTICERCOSE

Author

ALVES GULHOTE, DANIELA, primary, DE OLIVEIRA, AYME, additional, OLIVA DA FONSECA, JÚLIA, additional, IAFIGLIOLA GOMES, NICOLE, additional, DE LIMA BURNIER, VICTORIA, additional, BISTAFFA VITOR, GABRIELA, additional, SILVEIRA D’ANDRÉA ROSSI, GIOVANNI, additional, PERES, AMANDA, additional, GUERNELLI BATISTA, GIOVANA, additional, DUARTE, ROBERTA, additional, SANTOS DA SILVA, ARTHUR, additional, DE MORAES MANGAS, GABRIEL, additional, LUSTOSA CAMPOS, ENZO, additional, SANTOS DE OLIVEIRA, RICARDO, additional, and FERNANDO MANZOLLI BALLESTERO, MATHEUS, additional

Published
2023
Full Text
View/download PDF

24. Measurement of Sea Waves

Author

Piscopo, Vincenzo, Rossi, Giovanni Battista, Crenna, Francesco, Gaglione, Salvatore, Scamardella, Antonio, Uttieri, Marco, Zambianchi, Enrico, Cain, Markys G., Series Editor, Rossi, Giovanni Battista, Series Editor, Tesař, Jirí, Series Editor, van Veghel, Marijn, Series Editor, Jhang, Kyung-Young, Series Editor, Daponte, Pasquale, editor, and Piscopo, Vincenzo, editor

Published
2022
Full Text
View/download PDF

27. Editor's Choice – Early Outcomes of a Novel Off the Shelf Preloaded Inner Branch Endograft for the Treatment of Complex Aortic Pathologies in the ItaliaN Branched Registry of E-nside EnDograft (INBREED)

Author

Forcella, Edoardo, Grego, Franco, Spinella, Giovanni, Di Gregorio, Sara, Donati, Tommaso, Sica, Simona, Tinelli, Giovanni, Ferri, Michelangelo, Quaglino, Simone, Vento, Vincenzo, Carbonari, Luciano, Lenti, Massimo, Isernia, Giacomo, Parlani, Giambattista, Scrivere, Paola, Furlan, Federico, Mezzetto, Luca, Mastrorilli, Davide, Gennai, Stefano, Leone, Nicola, Iacono, Gustavo, Turricchia, Giorgio Ubaldo, Angiletta, Domenico, Maione, Massimo, Apostolou, Dimitri, Pulli, Raffaele, Fargion, Aaron, Pratesi, Carlo, Filippi, Federico, De Angelis, Filippo, Arici, Vittorio, Bozzani, Antonio, Luigi Molinari, Alessandro Carlo, Rossi, Giovanni, Brancadoro, Emidio Costantini, Ferraris, Matteo, Dorrucci, Vittorio, Derone, Graziana, Tolva, Valerio Stefano, Segramora, Vittorio Maria, Deleo, Gaetano, Bracale, Umberto, Guzzardi, Giuseppe, Ferrer, Ciro, Giudice, Rocco, Sbarigia, Enrico, Cuozzo, Simone, Gattuso, Roberto, Mansour, Wassim, Di Marzo, Luca, Grimaldi, Sabrina, Corona, Mario, Chisci, Emiliano, Mechelagnoli, Stefano, De Donato, Gianmarco, Palasciano, Giancarlo, Pasqui, Edoardo, Candeloro, Laura, Ricci, Carmelo, Neri, Eugenio, Mangialardi, Nicola, Orrico, Matteo, Fazzini, Stefano, Ippoliti, Arnaldo, Discalzi, Andrea, Rossato, Denis, Vio, Elias, Galeazzi, Edoardo, Farneti, Fabrizio, Piazza, Michele, Squizzato, Francesco, Pratesi, Giovanni, Tshomba, Yamume, Gaggiano, Andrea, Gatta, Emanuele, Simonte, Gioele, Piffaretti, Gabriele, Frigatti, Paolo, Veraldi, Gian Franco, Silingardi, Roberto, and Antonello, Michele

Published
2023
Full Text
View/download PDF

29. An Italian prospective multicenter study on colonoscopy practice and quality: What has changed in the last 10 years

Author

Alvisi, Costanza, Amato, Loretta, Azzurro, Maurizio, Benazzato, Luca, Bianco, Maria Antonia, Biviano, Ivano, Bravi, Ivana, Brunacci, Matteo, Bucci, Cristina, Buonocore, Matteo Rossano, Cadoni, Sergio, Camellini, Lorenzo, Capone, Pietro, Cavallaro, Lucas G., Condino, Giovanna, Crosta, Cristiano, de Bellis, Mario, de Colibus, Patrizia, de Nigris, Francesca, Esposito, Dario, Fiori, Giancarla, Fornasarig, Mara, Fracchia, Mario, Gemme, Carlo, Germanà, Bastianello, Gianni, Elena, Giunta, Mariangela, Guarnieri, Giovanni, Iabichino, Giuseppe, Luigiano, Carmelo, Maiero, Stefania, Marini, Mario, Marone, Pietro, Meucci, Costantino, Morandi, Elisabetta, Mura, Donatella, Nucci, Andrea, Peccianti, Caterina, Praianò, Francesca, Prisco, Antonio, Rastelli, Carlotta, Ravizza, Davide, Rocca, Rodolfo, Rosa, Cesare, Rossi, Giovanni Battista, Sannino, Angela, Testoni, Sabrina, Urban, Flavia, Testoni, Pier Alberto, Notaristefano, Chiara, Soncini, Marco, Hassan, Cesare, Monica, Fabio, Radaelli, Franco, Triossi, Omero, Pasquale, Luigi, Neri, Matteo, Cannizzaro, Renato, and Leandro, Gioacchino

Published
2023
Full Text
View/download PDF

31. Solutions of partition function-based TU games for cooperative communication networking

Author

Rossi, Giovanni

Subjects
Computer Science - Computer Science and Game Theory
Abstract

In networked communications nodes choose among available actions and benefit from exchanging information through edges, while continuous technological progress fosters system functionings that increasingly often rely on cooperation. Growing attention is being placed on coalition formation, where each node chooses what coalition to join, while the surplus generated by cooperation is an amount of TU (transferable utility) quantified by a real-valued function defined on partitions -or even embedded coalitions- of nodes. A TU-sharing rule is thus essential, as how players are rewarded determines their behavior. This work offers a new option for distributing partition function-based surpluses, dealing with cooperative game theory in terms of both global games and games in partition function form, namely lattice functions, while the sharing rule is a point-valued solution or value. The novelty is grounded on the combinatorial definition of such solutions as lattice functions whose M\"obius inversion lives only on atoms, i.e. on the first level of the lattice. While simply rephrasing the traditional solution concept for standard coalitional games, this leads to distribute the surplus generated by partitions across the edges of the network, as the atoms among partitions are unordered pairs of players. These shares of edges are further divided between nodes, but the corresponding Shapley value is very different from the traditional one and leads to two alternative forms, obtained by focusing either on marginal contributions along maximal chains, or else on the uniform division of Harsanyi dividends. The core is also addressed, and supermodularity is no longer sufficient for its non-emptiness., Comment: 10 pages. arXiv admin note: text overlap with arXiv:0905.4057 by other authors

Published
2018

32. Searching for network modules

Author

Rossi, Giovanni

Subjects
Computer Science - Discrete Mathematics, Computer Science - Social and Information Networks
Abstract

When analyzing complex networks a key target is to uncover their modular structure, which means searching for a family of modules, namely node subsets spanning each a subnetwork more densely connected than the average. This work proposes a novel type of objective function for graph clustering, in the form of a multilinear polynomial whose coefficients are determined by network topology. It may be thought of as a potential function, to be maximized, taking its values on fuzzy clusterings or families of fuzzy subsets of nodes over which every node distributes a unit membership. When suitably parametrized, this potential is shown to attain its maximum when every node concentrates its all unit membership on some module. The output thus is a partition, while the original discrete optimization problem is turned into a continuous version allowing to conceive alternative search strategies. The instance of the problem being a pseudo-Boolean function assigning real-valued cluster scores to node subsets, modularity maximization is employed to exemplify a so-called quadratic form, in that the scores of singletons and pairs also fully determine the scores of larger clusters, while the resulting multilinear polynomial potential function has degree 2. After considering further quadratic instances, different from modularity and obtained by interpreting network topology in alternative manners, a greedy local-search strategy for the continuous framework is analytically compared with an existing greedy agglomerative procedure for the discrete case. Overlapping is finally discussed in terms of multiple runs, i.e. several local searches with different initializations., Comment: 10 pages

Published
2018

33. Multiple Regression Model to Analyze the Length of Stay for Patients Undergoing Laparoscopic Appendectomy: A Bicentric Study

Author

Montella, Emma, primary, Marino, Marta Rosaria, additional, Frangiosa, Alessandro, additional, Mazia, Giuseppe, additional, Majolo, Massimo, additional, Raiola, Eliana, additional, Russo, Giuseppe, additional, Longo, Giuseppe, additional, Rossi, Giovanni, additional, Borrelli, Anna, additional, and Triassi, Maria, additional

Published
2023
Full Text
View/download PDF

42. The Role of Rituximab in Primary Focal Segmental Glomerular Sclerosis of the Adult

Author

Affatato, Stefania, Caroti, Leonardo, Mancini, Elena, Semeraro, Luca, Siligato, Rossella, Arnaldo Cassia, Matthias, Napodano, Pietro, Calatroni, Marta, Distratis, Cosimo, Campo, Andrea, Tedesco, Martina, Mescia, Federica, Pisani, Isabella, Allinovi, Marco, Casazza, Giovanni, Del Vecchio, Lucia, Santostefano, Marisa, Cirillo, Luigi, Ferrario, Francesca, Esposito, Ciro, Esposito, Pasquale, Santoro, Domenico, Lazzarin, Roberta, Rossi, Giovanni Maria, Fiaccadori, Enrico, Ferrantelli, Angelo, Sinico, Renato Alberto, Cozzolino, Mario, Gallieni, Maurizio, Cirami, Lino, Scolari, Francesco, Vaglio, Augusto, and Alberici, Federico

Published
2022
Full Text
View/download PDF

46. Proximal sealing in the aortic arch for inner curve disease using the custom Relay scalloped and fenestrated stent graft.

Author

Sica, Simona, Pratesi, Giovanni, Rossi, Giovanni, Ferraresi, Marco, Lovato, Luigi, Volpe, Pietro, Fadda, Gian Franco, Ferri, Michelangelo, Rizza, Antonio, D'Oria, Mario, Micheli, Raimondo, Tshomba, Yamume, and Tinelli, Giovanni

Abstract

This study aimed to analyze early and midterm results of custom-made proximal scallop and fenestrated stent grafts for thoracic endovascular aortic repair (TEVAR) with a proximal landing zone (PLZ) in the aortic arch. All consecutive patients treated with the custom made proximal scalloped and fenestrated Relay stent grafts (Terumo Aortic Bolton Medical Inc.) in 10 Italian centers between January 2014 and December 2022 were included. The primary end points were technical success, incidence of intraoperative major adverse events, deployment accuracy, and rate of early neurological complications, endoleaks (ELs) and retrograde aortic dissection. During the study period, 49 patients received TEVAR with Relay custom-made endograft in Italy were enrolled. The median patient age was 70.1 years (interquartile range, 23-86 years) and 65.3% were male. The indication for treatment was atherosclerotic aneurysms in 59.2% of cases and penetrating aortic ulcer in 22.4%. The endograft configuration was proximal fenestration in 55.1% and scallop in 44.9%. The proximal landing zone was zone 0 in 25 cases (51%), zone 1 in 14 cases (28.6%), and zone 2 in 10 cases (20.4%). The supra-aortic debranching procedures were 38 (77.5%). Technical success was 97.9% (48/49) owing to one case (2.0%) of inaccurate deployment. Intraoperatively, one (2.0%) type Ia and one (2.0%) type III EL were detected. There were no cases of in-hospital mortality, major adverse events, or retrograde dissection. Three minor strokes (6.1%) (National Institutes of Health Stroke Scale score of ≤4) were observed. At a mean follow-up time of 36.3 ± 21.3 months the rate of types I to III ELs and reintervention was 4.1%, respectively. Four patients (8.2%) died during the follow-up period, one (2.1%) from abdominal aortic rupture and three (6.1%) from nonaortic causes. Our early and midterm outcomes suggest that scalloped and fenestrated TEVAR may provide an acceptable alternative treatment option for aortic arch pathologies. Large-scale studies are needed to assess the long-term durability of this technique. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

47. The Controversial Role of Glucocorticoids in Atheroembolic Renal Disease: A Narrative Review.

Author

Pacchiarini, Maria Chiara, Di Mario, Francesca, Greco, Paolo, Fiaccadori, Enrico, and Rossi, Giovanni Maria

Subjects
ACUTE kidney failure, ATHEROSCLEROTIC plaque, DELAYED diagnosis, CYTOTOXINS, ANTI-inflammatory agents
Abstract

Cholesterol crystal embolism (CCE) is an underrecognized multisystemic disease caused by the displacement of cholesterol crystals from atheromatous aortic plaques to distal vascular beds, leading to ischemic injury of target organs, particularly the kidneys, i.e., atheroembolic renal disease (ARD). According to recent research, cellular necrosis, induced by crystal-induced cytotoxicity, enhances the autoinflammatory cascade of the NLPR3 inflammasome, leading in turn to the so-called "necroinflammation". The purported involvement of the latter in CCE offers a rationale for the therapeutic approach with anti-inflammatory drugs such as glucocorticoids, the use of which has long been a matter of debate in CCE. Diagnostic delay and no consistent evidence regarding efficacious treatment, leading to inconsistency in clinical practice, may worsen the already poor prognosis of ARD. The possible role of glucocorticoids in the treatment of ARD is thereby herein explored in a narrative fashion, analyzing the limited data from case reports and clinical trials. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results