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2. Sexual Dysfunction in Functional Hypothalamic Amenorrhea

Author

Nappi, Rossella, Barbagallo, Federica, Bosoni, David, Cucinella, Laura, Stincardini, Giulia, Righi, Alessandra, Piccinino, Manuela, Rossini, Roberta, Tiranini, Lara, Genazzani, Andrea R., Series Editor, Hirschberg, Angelica Lindén, editor, Genazzani, Alessandro D., editor, Nappi, Rossella, editor, and Vujovic, Svetlana, editor

Published
2023
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3. Achievement of target LDL-cholesterol level in patients with acute coronary syndrome undergoing percutaneous coronary intervention: The JET-LDL registry

Author

Ferlini, Marco, Munafò, Andrea, Varbella, Ferdinando, Delnevo, Fabrizio, Solli, Martina, Trabattoni, Daniela, Piccaluga, Emanuela, Cardile, Antonino, Canova, Paolo, Rossini, Roberta, Celentani, Dario, Ugo, Fabrizio, Taglialatela, Vittorio, Airoldi, Falvio, Rognoni, Andrea, Oliva, Fabrizio, Porto, Italo, Carugo, Stefano, Castiglioni, Battistina, Lettieri, Corrado, Chinaglia, Alessandra, Currao, Alessia, Patti, Giuseppe, Oltrona Visconti, Luigi, and Musumeci, Giuseppe

Published
2024
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4. Quality of Life and Sexual Health

Author

Tiranini, Lara, Stincardini, Giulia, Righi, Alessandra, Cucinella, Laura, Piccinino, Manuela, Rossini, Roberta, Nappi, Rossella E., Genazzani, Andrea R., Series Editor, Ibáñez, Lourdes, editor, Milewicz, Andrzej, editor, and Shah, Duru, editor

Published
2021
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6. Aspirin in Primary Prevention: Looking for Those Who Enjoy It.

Author

Della Bona, Roberta, Giubilato, Simona, Palmieri, Marco, Benenati, Stefano, Rossini, Roberta, Di Fusco, Stefania Angela, Novarese, Filippo, Mascia, Giuseppe, Gasparetto, Nicola, Di Monaco, Antonio, Gatto, Laura, Zilio, Filippo, Sorini Dini, Carlotta, Borrello, Francesco, Geraci, Giovanna, Riccio, Carmine, De Luca, Leonardo, Colivicchi, Furio, Grimaldi, Massimo, and Giulizia, Michele Massimo

Subjects
ANTILIPEMIC agents, ASPIRIN, CANCER prevention, CARDIOVASCULAR diseases risk factors, DISEASE risk factors
Abstract

Based on a wealth of evidence, aspirin is one of the cornerstones of secondary prevention of cardiovascular disease. However, despite several studies showing efficacy also in primary prevention, an unopposed excess risk of bleeding leading to a very thin safety margin is evident in subjects without a clear acute cardiovascular event. Overall, the variability in recommendations from different scientific societies for aspirin use in primary prevention is a classic example of failure of simple risk stratification models based on competing risks (atherothrombosis vs. bleeding), perceived to be opposed but intertwined at the pathophysiological level. Notably, cardiovascular risk is dynamic in nature and cannot be accurately captured by scores, which do not always consider risk enhancers. Furthermore, the widespread use of other potent medications in primary prevention, such as lipid-lowering and anti-hypertensive drugs, might be reducing the benefit of aspirin in recent trials. Some authors, drawing from specific pathophysiological data, have suggested that specific subgroups might benefit more from aspirin. This includes patients with diabetes and those with obesity; sex-based differences are considered as well. Moreover, molecular analysis of platelet reactivity has been proposed. A beneficial effect of aspirin has also been demonstrated for the prevention of cancer, especially colorectal. This review explores evidence and controversies concerning the use of aspirin in primary prevention, considering new perspectives in order to provide a comprehensive individualized approach. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Achievement of target LDL-cholesterol level in patients with acute coronary syndrome undergoing percutaneous coronary intervention: The JET-LDL registry

Author

Ferlini, Marco, primary, Munafò, Andrea, additional, Varbella, Ferdinando, additional, Delnevo, Fabrizio, additional, Solli, Martina, additional, Trabattoni, Daniela, additional, Piccaluga, Emanuela, additional, Cardile, Antonino, additional, Canova, Paolo, additional, Rossini, Roberta, additional, Celentani, Dario, additional, Ugo, Fabrizio, additional, Taglialatela, Vittorio, additional, Airoldi, Falvio, additional, Rognoni, Andrea, additional, Oliva, Fabrizio, additional, Porto, Italo, additional, Carugo, Stefano, additional, Castiglioni, Battistina, additional, Lettieri, Corrado, additional, Chinaglia, Alessandra, additional, Currao, Alessia, additional, Patti, Giuseppe, additional, Visconti, Luigi Oltrona, additional, and Musumeci, Giuseppe, additional

Published
2023
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8. Gastroprotection in patients on antiplatelet and/or anticoagulant therapy: a position paper of National Association of Hospital Cardiologists (ANMCO) and the Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO)

Author

Abrignani, Maurizio Giuseppe, Gatta, Luigi, Gabrielli, Domenico, Milazzo, Giuseppe, De Francesco, Vincenzo, De Luca, Leonardo, Francese, Maura, Imazio, Massimo, Riccio, Elisabetta, Rossini, Roberta, Scotto di Uccio, Fortunato, Soncini, Marco, Zullo, Angelo, Colivicchi, Furio, Di Lenarda, Andrea, Gulizia, Michele Massimo, and Monica, Fabio

Published
2021
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9. Aspirin hypersensitivity: a practical guide for cardiologists.

Author

Grimaldi, Silvia, Migliorini, Paola, Puxeddu, Ilaria, Rossini, Roberta, and Caterina, Raffaele De

Subjects
PROSTHETIC heart valves, ASPIRIN, MYOCARDIAL infarction, PLATELET aggregation inhibitors, ORAL medication, ACUTE coronary syndrome
Abstract

Aspirin has been known for a long time and currently stays as a cornerstone of antithrombotic therapy in cardiovascular disease. In patients with either acute or chronic coronary syndromes undergoing percutaneous coronary intervention aspirin is mandatory in a dual antiplatelet therapy regimen for prevention of stent thrombosis and/or new ischaemic events. Aspirin is also currently a first-option antithrombotic therapy after an aortic prosthetic valve replacement and is occasionally required in addition to oral anticoagulants after implantation of a mechanical valve. Presumed or demonstrated aspirin hypersensitivity is a main clinical problem, limiting the use of a life-saving medication. In the general population, aspirin hypersensitivity has a prevalence of 0.6%–2.5% and has a plethora of clinical presentations, ranging from aspirin-exacerbated respiratory disease to anaphylaxis. Although infrequent, when encountered in clinical practice aspirin hypersensitivity poses for cardiologists a clinical dilemma, which should never be trivialized, avoiding—as much as possible—omission of the drug. We here review the epidemiology of aspirin hypersensitivity, provide an outline of pathophysiological mechanisms and clinical presentations, and review management options, starting from a characterization of true aspirin allergy—in contrast to intolerance—to suggestion of desensitization protocols. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Hormonally Related Headaches

Author

Nappi, Rossella E., Martella, Silvia, Sances, Grazia, Piccinino, Manuela, Rossini, Roberta, Tiranini, Lara, Brambilla, Emanuela, Franco, Alessandro Kunder, Inzoli, Alessandra, Tassorelli, Cristina, Genazzani, Andrea R., Series Editor, Berga, Sarah L., editor, Naftolin, Frederick, editor, and Petraglia, Felice, editor

Published
2019
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11. Management of Residual Risk in Chronic Coronary Syndromes. Clinical Pathways for a Quality-Based Secondary Prevention

Author

Giubilato, Simona, primary, Lucà, Fabiana, additional, Abrignani, Maurizio Giuseppe, additional, Gatto, Laura, additional, Rao, Carmelo Massimiliano, additional, Ingianni, Nadia, additional, Amico, Francesco, additional, Rossini, Roberta, additional, Caretta, Giorgio, additional, Cornara, Stefano, additional, Di Matteo, Irene, additional, Di Nora, Concetta, additional, Favilli, Silvia, additional, Pilleri, Anna, additional, Pozzi, Andrea, additional, Temporelli, Pier Luigi, additional, Zuin, Marco, additional, Amico, Antonio Francesco, additional, Riccio, Carmine, additional, Grimaldi, Massimo, additional, Colivicchi, Furio, additional, Oliva, Fabrizio, additional, and Gulizia, Michele Massimo, additional

Published
2023
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12. Management of Patients Treated with Direct Oral Anticoagulants in Clinical Practice and Challenging Scenarios

Author

Lucà, Fabiana, primary, Oliva, Fabrizio, additional, Abrignani, Maurizio Giuseppe, additional, Di Fusco, Stefania Angela, additional, Parrini, Iris, additional, Canale, Maria Laura, additional, Giubilato, Simona, additional, Cornara, Stefano, additional, Nesti, Martina, additional, Rao, Carmelo Massimiliano, additional, Pozzi, Andrea, additional, Binaghi, Giulio, additional, Maloberti, Alessandro, additional, Ceravolo, Roberto, additional, Bisceglia, Irma, additional, Rossini, Roberta, additional, Temporelli, Pier Luigi, additional, Amico, Antonio Francesco, additional, Calvanese, Raimondo, additional, Gelsomino, Sandro, additional, Riccio, Carmine, additional, Grimaldi, Massimo, additional, Colivicchi, Furio, additional, and Gulizia, Michele Massimo, additional

Published
2023
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13. Italian Association of Hospital Cardiologists Position Paper ‘Gender discrepancy: time to implement gender-based clinical management’

Author

Lucà, Fabiana, Pavan, Daniela, Gulizia, Michele Massimo, Manes, Maria Teresa, Abrignani, Maurizio Giuseppe, Benedetto, Francesco Antonio, Bisceglia, Irma, Brigido, Silvana, Caldarola, Pasquale, Calvanese, Raimondo, Canale, Maria Laura, Caretta, Giorgio, Ceravolo, Roberto, Chieffo, Alaide, Chimenti, Cristina, Cornara, Stefano, Cutolo, Ada, Di Fusco, Stefania Angela, Di Matteo, Irene, Di Nora, Concetta, Fattirolli, Francesco, Favilli, Silvia, Francese, Giuseppina Maura, Gelsomino, Sandro, Geraci, Giovanna, Giubilato, Simona, Ingianni, Nadia, Iorio, Annamaria, Lanni, Francesca, Montalto, Andrea, Nardi, Federico, Navazio, Alessandro, Nesti, Martina, Parrini, Iris, Pilleri, Annarita, Pozzi, Andrea, Rao, Carmelo Massimiliano, Riccio, Carmine, Rossini, Roberta, Scicchitano, Pietro, Valente, Serafina, Zuccalà, Giuseppe, Gabrielli, Domenico, Grimaldi, Massimo, Colivicchi, Furio, and Oliva, Fabrizio

Abstract

It has been well assessed that women have been widely under-represented in cardiovascular clinical trials. Moreover, a significant discrepancy in pharmacological and interventional strategies has been reported. Therefore, poor outcomes and more significant mortality have been shown in many diseases. Pharmacokinetic and pharmacodynamic differences in drug metabolism have also been described so that effectiveness could be different according to sex. However, awareness about the gender gap remains too scarce. Consequently, gender-specific guidelines are lacking, and the need for a sex-specific approach has become more evident in the last few years. This paper aims to evaluate different therapeutic approaches to managing the most common women’s diseases.

Published
2024
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15. Anderson–Fabry Disease: Red Flags for Early Diagnosis of Cardiac Involvement.

Author

Iorio, Annamaria, Lucà, Fabiana, Pozzi, Andrea, Rao, Carmelo Massimiliano, Chimenti, Cristina, Di Fusco, Stefania Angela, Rossini, Roberta, Caretta, Giorgio, Cornara, Stefano, Giubilato, Simona, Di Matteo, Irene, Di Nora, Concetta, Pilleri, Anna, Gelsomino, Sandro, Ceravolo, Roberto, Riccio, Carmine, Grimaldi, Massimo, Colivicchi, Furio, Oliva, Fabrizio, and Gulizia, Michele Massimo

Subjects
ANGIOKERATOMA corporis diffusum, ARRHYTHMIA, LEFT ventricular hypertrophy, EARLY diagnosis, SUDDEN death, GENETIC testing
Abstract

Anderson–Fabry disease (AFD) is a lysosome storage disorder resulting from an X-linked inheritance of a mutation in the galactosidase A (GLA) gene encoding for the enzyme alpha-galactosidase A (α-GAL A). This mutation results in a deficiency or absence of α-GAL A activity, with a progressive intracellular deposition of glycosphingolipids leading to organ dysfunction and failure. Cardiac damage starts early in life, often occurring sub-clinically before overt cardiac symptoms. Left ventricular hypertrophy represents a common cardiac manifestation, albeit conduction system impairment, arrhythmias, and valvular abnormalities may also characterize AFD. Even in consideration of pleiotropic manifestation, diagnosis is often challenging. Thus, knowledge of cardiac and extracardiac diagnostic "red flags" is needed to guide a timely diagnosis. Indeed, considering its systemic involvement, a multidisciplinary approach may be helpful in discerning AFD-related cardiac disease. Beyond clinical pearls, a practical approach to assist clinicians in diagnosing AFD includes optimal management of biochemical tests, genetic tests, and cardiac biopsy. We extensively reviewed the current literature on AFD cardiomyopathy, focusing on cardiac "red flags" that may represent key diagnostic tools to establish a timely diagnosis. Furthermore, clinical findings to identify patients at higher risk of sudden death are also highlighted. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Appropriateness of Dyslipidemia Management Strategies in Post-Acute Coronary Syndrome: A 2023 Update

Author

Lucà, Fabiana, primary, Oliva, Fabrizio, additional, Rao, Carmelo Massimiliano, additional, Abrignani, Maurizio Giuseppe, additional, Amico, Antonio Francesco, additional, Di Fusco, Stefania Angela, additional, Caretta, Giorgio, additional, Di Matteo, Irene, additional, Di Nora, Concetta, additional, Pilleri, Anna, additional, Ceravolo, Roberto, additional, Rossini, Roberta, additional, Riccio, Carmine, additional, Grimaldi, Massimo, additional, Colivicchi, Furio, additional, and Gulizia, Michele Massimo, additional

Published
2023
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18. The role of the pregnancy heart team in clinical practice

Author

Lucà, Fabiana, Colivicchi, Furio, Parrini, Iris, Russo, Maria Giovanna, Di Fusco, Stefania Angela, Ceravolo, Roberto, Riccio, Carmine, Favilli, Silvia, Rossini, Roberta, Gelsomino, Sandro, Oliva, Fabrizio, Gulizia, Michele Massimo, Lucà, Fabiana, Colivicchi, Furio, Parrini, Iri, Russo, Maria Giovanna, Di Fusco, Stefania Angela, Ceravolo, Roberto, Riccio, Carmine, Favilli, Silvia, Rossini, Roberta, Gelsomino, Sandro, Oliva, Fabrizio, and Gulizia, Michele Massimo

Subjects
postpartum followup, pre-conception counseling, corrected congenital heart disease, acquired heart disease, cardio obstetric team, pregnancy heart team, Cardiology and Cardiovascular Medicine, multidisciplinary team-Based approach
Abstract

Significant maternal and fetal morbidity and mortality risk has been shown to be associated with cardiovascular disease in pregnancy. Several determinants, such as the increasing number of females with corrected congenital heart disease in reproductive age, a more advanced maternal age associated with cardiovascular risk factors, and a greater prevalence of preexisting comorbidities related to cardiac disorders such as cancer and COVID-19), lead to a higher incidence of cardiac complications in pregnancy in the last few decades. However, adopting a multidisciplinary strategy may influence maternal and neonatal outcomes. This review aims at assessing the role of the Pregnancy Heart Team, which should ensure careful pre-pregnancy counseling, pregnancy monitoring, and delivery planning for both congenital and other cardiac or metabolic disorders, addressing several emerging aspects in the multidisciplinary team-based approach.

Published
2023

19. A Multidisciplinary Approach on the Perioperative Antithrombotic Management of Patients With Coronary Stents Undergoing Surgery: Surgery After Stenting 2

Author

Rossini, Roberta, Tarantini, Giuseppe, Musumeci, Giuseppe, Masiero, Giulia, Barbato, Emanuele, Calabrò, Paolo, Capodanno, Davide, Leonardi, Sergio, Lettino, Maddalena, Limbruno, Ugo, Menozzi, Alberto, Marchese, U.O. Alfredo, Saia, Francesco, Valgimigli, Marco, Ageno, Walter, Falanga, Anna, Corcione, Antonio, Locatelli, Alessandro, Montorsi, Marco, Piazza, Diego, Stella, Andrea, Bozzani, Antonio, Parolari, Alessandro, Carone, Roberto, and Angiolillo, Dominick J.

Published
2018
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21. Patients with non-ST segment elevation acute coronary syndromes managed without coronary revascularization: A population needing treatment improvement

Author

Menozzi, Alberto, De Servi, Stefano, Rossini, Roberta, Ferlini, Marco, Lina, Daniela, Abrignani, Maurizio Giuseppe, Capranzano, Piera, Carrabba, Nazario, Galvani, Marcello, Marchese, Alfredo, Mazzotta, Gianfranco, Moretti, Luciano, Signore, Nicola, Uguccioni, Massimo, Olivari, Zoran, and De Luca, Leonardo

Published
2017
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22. Management of oral anticoagulant therapy after intracranial hemorrhage in patients with atrial fibrillation

Author

Lucà, Fabiana, primary, Colivicchi, Furio, additional, Oliva, Fabrizio, additional, Abrignani, Maurizio, additional, Caretta, Giorgio, additional, Di Fusco, Stefania Angela, additional, Giubilato, Simona, additional, Cornara, Stefano, additional, Di Nora, Concetta, additional, Pozzi, Andrea, additional, Di Matteo, Irene, additional, Pilleri, Anna, additional, Rao, Carmelo Massimiliano, additional, Parlavecchio, Antonio, additional, Ceravolo, Roberto, additional, Benedetto, Francesco Antonio, additional, Rossini, Roberta, additional, Calvanese, Raimondo, additional, Gelsomino, Sandro, additional, Riccio, Carmine, additional, and Gulizia, Michele Massimo, additional

Published
2023
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24. The r’-Wave Algorithm: A New Diagnostic Tool to Predict the Diagnosis of Brugada Syndrome after a Sodium Channel Blocker Provocation Test

Author

Vetta, Giampaolo, primary, Parlavecchio, Antonio, additional, Pistelli, Lorenzo, additional, Desalvo, Paolo, additional, Lo Savio, Armando, additional, Magnocavallo, Michele, additional, Caminiti, Rodolfo, additional, Tribuzio, Anna, additional, Vairo, Alessandro, additional, La Maestra, Diego, additional, Vetta, Francesco, additional, Dattilo, Giuseppe, additional, Luzza, Francesco, additional, Di Bella, Gianluca, additional, Rossini, Roberta, additional, Della Rocca, Domenico Giovanni, additional, and Crea, Pasquale, additional

Published
2023
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25. Hormonally Related Headaches

Author

Nappi, Rossella E., primary, Martella, Silvia, additional, Sances, Grazia, additional, Piccinino, Manuela, additional, Rossini, Roberta, additional, Tiranini, Lara, additional, Brambilla, Emanuela, additional, Franco, Alessandro Kunder, additional, Inzoli, Alessandra, additional, and Tassorelli, Cristina, additional

Published
2019
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28. A large, prospective, multicentre study of left main PCI using a latest-generation zotarolimus-eluting stent: the ROLEX study

Author

Tarantini, Giuseppe, primary, Fovino, Luca Nai, additional, Varbella, Ferdinando, additional, Trabattoni, Daniela, additional, Caramanno, Giuseppe, additional, Trani, Carlo, additional, De Cesare, Nicoletta, additional, Esposito, Giovanni, additional, Montorfano, Matteo, additional, Musto, Carmine, additional, Picchi, Andrea, additional, Sheiban, Imad, additional, Gasparetto, Valeria, additional, Ribichini, Flavio L., additional, Cardaioli, Francesco, additional, Saccà, Salvatore, additional, Cerrato, Enrico, additional, Napodano, Massimo, additional, Martinato, Matteo, additional, Azzolina, Danila, additional, Andò, Giuseppe, additional, Mugnolo, Antonio, additional, Caruso, Marco, additional, Rossini, Roberta, additional, Passamonti, Enrico, additional, Teles, Rui Campante, additional, Rigattieri, Stefano, additional, Gregori, Dario, additional, Tamburino, Corrado, additional, and Burzotta, Francesco, additional

Published
2023
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33. Management and Long-Term Prognosis of Spontaneous Coronary Artery Dissection

Author

Lettieri, Corrado, Zavalloni, Dennis, Rossini, Roberta, Morici, Nuccia, Ettori, Federica, Leonzi, Ornella, Latib, Azeem, Ferlini, Marco, Trabattoni, Daniela, Colombo, Paola, Galli, Mario, Tarantini, Giuseppe, Napodano, Massimo, Piccaluga, Emanuela, Passamonti, Enrico, Sganzerla, Paolo, Ielasi, Alfonso, Coccato, Micol, Martinoni, Alessandro, Musumeci, Giuseppe, Zanini, Roberto, and Castiglioni, Battistina

Published
2015
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35. A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Dose-Finding Trial of the Oral Factor XIa Inhibitor Asundexian to Prevent Adverse Cardiovascular Outcomes After Acute Myocardial Infarction

Author

Rao, Sunil V., primary, Kirsch, Bodo, additional, Bhatt, Deepak L., additional, Budaj, Andrzej, additional, Coppolecchia, Rosa, additional, Eikelboom, John, additional, James, Stefan K., additional, Jones, W. Schuyler, additional, Merkely, Bela, additional, Keller, Lars, additional, Hermanides, Renicus S., additional, Campo, Gianluca, additional, Ferreiro, José Luis, additional, Shibasaki, Taro, additional, Mundl, Hardi, additional, Alexander, John H., additional, Hengstenberg, Christian, additional, Steinwender, Clemens, additional, Alber, Hannes, additional, Steringer-Mascherbauer, Regina, additional, Schober, Andreas, additional, Auer, Johann, additional, Roithinger, Franz Xaver, additional, von Lewinski, Dirk, additional, Moertl, Deddo, additional, Huber, Kurt, additional, Coussement, Patrick, additional, Hoffer, Etienne, additional, Beauloye, Christophe, additional, Janssens, Luc, additional, Vranckx, Pascal, additional, De Raedt, Herbert, additional, Vanassche, Thomas, additional, Vrolix, Matthias, additional, Rokyta, Richard, additional, Parenica, Jiri, additional, Pelouch, Radek, additional, Motovska, Zuzanna, additional, Alan, David, additional, Kettner, Jiri, additional, Polasek, Rostislav, additional, Cermak, Ondrej, additional, Sedlon, Pavel, additional, Hanis, Jiri, additional, Novak, Martin, additional, Belohlavek, Jan, additional, Horacek, Thomas, additional, Leggewie, Stefan, additional, Wenzel, Philip, additional, vom Dahl, Juergen, additional, Sievers, Burkhard, additional, Pulz, Jan, additional, Schellong, Sebastian, additional, Clemmensen, Peter, additional, Muller-Hennessen, Matthias, additional, Rassaf, Tienush, additional, Falukozi, Jozsef, additional, Ruzsa, Zoltan, additional, Tomcsanyi, Janos, additional, Csanadi, Zoltan, additional, Herczeg, Bela, additional, Koszegi, Zsolt, additional, Vorobcsuk, Andras, additional, Kiss, Robert, additional, Baranyai, Csaba, additional, Dezsi, Csaba, additional, Lupkovics, Geza, additional, Rossini, Roberta, additional, Scherillo, Marino, additional, Sergio Saba, Pier, additional, Calogero Campo, Gianluca, additional, Calo, Leonardo, additional, Nassiacos, Daniele, additional, Quadri, Giorgio, additional, Sciahbasi, Alessandro, additional, Silvio Marenzi, Gian Carlo, additional, Reimers, Bernhard, additional, Perna, Gian Piero, additional, Sacca, Salvatore, additional, Fattore, Luciano, additional, Brunelli, Claudio, additional, Picchi, Andrea, additional, Kuramochi, Takehiko, additional, Kondo, Kazuhisa, additional, Aoyama, Takahiko, additional, Kudoh, Takashi, additional, Yamamoto, Tadashi, additional, Takaya, Tomofumi, additional, Mukai, Yasushi, additional, Fukui, Kazuki, additional, Morioka, Nobuyuki, additional, Ando, Kenji, additional, Yamamuro, Atsushi, additional, Morita, Yasuhiro, additional, Koga, Yasuaki, additional, Watanabe, Tetsuya, additional, Sakamoto, Tomohiro, additional, Maebuchi, Daisuke, additional, Takahashi, Akihiko, additional, Yonetsu, Taishi, additional, Kakuta, Tsunekazu, additional, Nishina, Hidetaka, additional, Oemrawsingh, Rohit, additional, Dorman, Reinhart, additional, Oude Ophius, Ton, additional, Prins, Paco, additional, al Windy, N.Y.Y., additional, Zoet-Nugteren, S.K., additional, Hermanides, Rik, additional, van Eck, Martijn, additional, Scherptong, Roderick, additional, Cornel, J.H., additional, Damman, Peter, additional, Bech, Gerhard, additional, Torquay, R., additional, Kietselaer, Bas, additional, Grzelakowski, Pawel, additional, Krzysztof, Dyrbus, additional, Miekus, Pawel, additional, Przybylski, Andrzej, additional, Zarebinski, Maciej, additional, Balsam, Pawel, additional, Szachniewicz, Joanna, additional, Gierlotka, Marek, additional, Tycinska, Agnieszka, additional, Iniguez Romo, Andres, additional, Fernandez Ortiz, Antonio, additional, Carrasquer Cucarella, Anna, additional, Sanmartin Fernandez, Marcelo, additional, Sionis, Alessandro, additional, Bueno Zamora, Hector, additional, Ferreiro Gutierrez, Jose Luis, additional, Almenar, Luis, additional, Ferreira Gonzalez, Ignacio, additional, Pascual Figal, Domingo A., additional, Almendro Delia, Manuel, additional, Jimenez Fernandez, Miriam, additional, Skeppholm, Mika, additional, Zedigh, Crister, additional, Angeras, Oskar, additional, Lauermann, Jorg, additional, Erlinge, David, additional, Gustafsson, Robin, additional, Mooe, Thomas, additional, Utreras, Alejandro, additional, James, Stefan, additional, Grimfjard, Per, additional, Pedrazzini, Giovanni, additional, Mach, Francois, additional, Fournier, Stephane, additional, Haegeli, Laurent, additional, Beer, Jurg H., additional, Leibundgut, Gregor, additional, Kobza, Richard, additional, Kaiser, Christoph, additional, Kunadian, Vijay, additional, Al-Lamee, Rasha, additional, Gorog, Diana, additional, Khan, Sohail, additional, Trevelyan, Jasper, additional, Toor, Iqbal, additional, Smith, James, additional, Purushottam, Bhaskar, additional, Treasure, Charles, additional, Arena, Frank, additional, Vedere, Amarnath, additional, Henderson, David, additional, Gilani, Syed, additional, Jones, Alonzo, additional, Carrillo-Jimenez, Rodolfo, additional, Gillespie, Eve, additional, Marhefka, Gregary, additional, Wang, David, additional, Olson, Charles, additional, Bloom, Stephen, additional, Iftikhar, Faizan, additional, Brabham, David, additional, McGinty, John, additional, Thompson, Charles, additional, Talano, James, additional, Ginete, Wilson, additional, Williams, Marcus, additional, Masud, Ali, additional, Ariani, Mehrdad, additional, Bitar, Fahed, additional, Wang, Thomas, additional, and Samuelson, Bradley, additional

Published
2022
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36. Adherence of ticagrelOr in real world patients with aCute coronary syndrome: The AD-HOC study

Author

Fiocca, Luigi, primary, Rossini, Roberta, additional, Carioli, Greta, additional, Carobbio, Alessandra, additional, Piazza, Isabelle, additional, Collaku, Elona, additional, Giubilato, Simona, additional, Amico, Francesco, additional, Molfese, Maria, additional, De Benedictis, Mauro, additional, Calabria, Paolo, additional, Limbruno, Ugo, additional, Valente, Serafina, additional, Ferlini, Marco, additional, Spezzano, Tiziana, additional, Senni, Michele, additional, and Gavazzi, Antonello, additional

Published
2022
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38. A large, prospective, multicentre study of left main PCI using a latest-generation zotarolimus-eluting stent: the ROLEX study

Author

Tarantini, Giuseppe, Fovino, Luca Nai, Varbella, Ferdinando, Trabattoni, Daniela, Caramanno, Giuseppe, Trani, Carlo, De Cesare, Nicoletta, Esposito, Giovanni, Montorfano, Matteo, Musto, Carmine, Picchi, Andrea, Sheiban, Imad, Gasparetto, Valeria, Ribichini, Flavio L, Cardaioli, Francesco, Saccà, Salvatore, Cerrato, Enrico, Napodano, Massimo, Martinato, Matteo, Azzolina, Danila, Andò, Giuseppe, Mugnolo, Antonio, Caruso, Marco, Rossini, Roberta, Passamonti, Enrico, Teles, Rui Campante, Rigattieri, Stefano, Gregori, Dario, Tamburino, Corrado, and Burzotta, Francesco

Subjects
cardiovascular disease, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, pci, stent, heart disease, Cardiology and Cardiovascular Medicine
Abstract

Data on left main (LM) percutaneous coronary interventions (PCI) have mostly been obtained in studies using drug-eluting stent (DES) platforms without dedicated large-vessel devices and with limited expansion capability.Our study aimed to investigate the safety and efficacy of LM PCI with the latest-generation Resolute Onyx DES.ROLEX (Revascularization Of LEft main with resolute onyX) is a prospective, multicentre study (ClinicalTrials.gov: NCT03316833) enrolling patients with unprotected LM coronary artery disease and a SYNTAX score33 undergoing PCI with the Resolute Onyx zotarolimus-eluting coronary stent, that includes dedicated extra-large vessel platforms. The primary endpoint (EP) was target lesion failure (TLF): a composite of cardiac death, target vessel myocardial infarction (TVMI) and ischaemia-driven target lesion revascularisation (ID-TLR), at 1 year. All events were adjudicated by an independent clinical event committee. An independent core lab analysed all procedural angiograms.A total of 450 patients (mean age 71.8 years, SYNTAX score 24.5±7.2, acute coronary syndrome in 53%) were enrolled in 26 centres. Of these, 77% of subjects underwent PCI with a single-stent and 23% with a 2-stent technique (8% double kissing [DK] crush, 6% culotte, 9% T/T and small protrusion [TAP] stenting). Intravascular imaging guidance was used in 45% (42% intravascular ultrasound [IVUS], 3% optical coherence tomography [OCT]). At 1 year, the primary EP incidence was 5.1% (cardiac death 2.7%, TVMI 2.7%, ID-TLR 2.0%). The definite/probable stent thrombosis rate was 1.1%. In a prespecified adjusted subanalysis, the primary EP incidence was significantly lower in patients undergoing IVUS/OCT-guided versus angio-guided PCI (2.0 vs 7.6%; hazard ratio [HR] 0.28, 95% confidence interval [CI]: 0.13-0.58; p0.001).In this large, multicentre, prospective registry, LM PCI with the Resolute Onyx DES showed good safety and efficacy at 1 year, particularly when guided by intracoronary imaging.

Published
2022

39. A Tailored Antithrombotic Approach for Patients with Atrial Fibrillation Presenting with Acute Coronary Syndrome and/or Undergoing PCI: A Case Series

Author

Giubilato, Simona, primary, Lucà, Fabiana, additional, Pozzi, Andrea, additional, Caretta, Giorgio, additional, Cornara, Stefano, additional, Pilleri, Anna, additional, Di Nora, Concetta, additional, Amico, Francesco, additional, Di Matteo, Irene, additional, Favilli, Silvia, additional, Rossini, Roberta, additional, Riccio, Carmine, additional, Colivicchi, Furio, additional, and Gulizia, Michele Massimo, additional

Published
2022
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40. Menopause and female sexual dysfunctions

Author

CUCINELLA, Laura, primary, MARTINI, Ellis, additional, TIRANINI, Lara, additional, BATTISTA, Federica, additional, MOLINARO, Pietro, additional, CASIRAGHI, Arianna, additional, COMINOTTI, Selene, additional, PICCININO, Manuela, additional, ROSSINI, Roberta, additional, and NAPPI, Rossella E., additional

Published
2022
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41. Comparison of Reduced-Dose Prasugrel and Standard-Dose Clopidogrel in Elderly Patients With Acute Coronary Syndromes Undergoing Early Percutaneous Revascularization

Author

Savonitto, Stefano, Ferri, Luca A., Piatti, Luigi, Grosseto, Daniele, Piovaccari, Giancarlo, Morici, Nuccia, Bossi, Irene, Sganzerla, Paolo, Tortorella, Giovanni, Cacucci, Michele, Ferrario, Maurizio, Murena, Ernesto, Sibilio, Girolamo, Tondi, Stefano, Toso, Anna, Bongioanni, Sergio, Ravera, Amelia, Corrada, Elena, Mariani, Matteo, Di Ascenzo, Leonardo, Petronio, A. Sonia, Cavallini, Claudio, Vitrella, Giancarlo, Rogacka, Renata, Antonicelli, Roberto, Cesana, Bruno M., De Luca, Leonardo, Ottani, Filippo, De Luca, Giuseppe, Piscione, Federico, Moffa, Nadia, De Servi, Stefano, Bolognese, Leonardo, Bovenzi, Francesco, Steffenino, Giuseppe, Santilli, Ignazio, Bassanelli, Giorgio, Sacco, Alice, Canziani, Federico, Ferri, Marco, Lo Jacono, Emilia, Canosi, Umberto, Fornaro, Giuseppe, Leoncini, Mario, Rosa Conte, Maria, Farina, Rosario, Stefanin, Catia, Di Pede, Francesco, Chella, Piersilvio, Chiara Nardoni, M., Tamburrini, Paola, Trimarco, Bruno, Galasso, Gennaro, Elia, Raffaele, Bolognese, Leonardo, Grotti, Simone, Bovenzi, Francesco, Borrelli, Lucia, Tamburino, Corrado, Capranzano, Piera, Francaviglia, Bruno, Campana, Carlo, Bonatti, Roberto, Martinoni, Alessandro, Abate, Fabio, Coscarelli, Sebastian, Rubartelli, Paolo, Villani, Giovanni Q., and Rossini, Roberta

Published
2018
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42. [ANMCO Position paper: Care pathway for advanced heart failure patients candidate for heart transplantation/ventricular assist device]

Author

Iacoviello, Massimo, Cipriani, Manlio, Valente, Serafina, Marini, Marco, Ammirati, Enrico, Benvenuto, Manuela, Cassaniti, Leonarda Rosaria, De Maria, Renata, Gori, Mauro, Municinò, Annamaria, Navazio, Alessandro, Amodeo, Vincenzo, Aspromonte, Nadia, Barili, Fabio, Casolo, Giancarlo, Clemenza, Francesco, Di Eusanio, Marco, Di Lenarda, Andrea, Di Tano, Giuseppe, Domenicucci, Stefano, Faggian, Giuseppe, Francese, Giuseppina Maura, Frongillo, Doriana, Gilardi, Rossella, Iacovoni, Attilio, Imazio, Massimo, Livi, Ugolino, Maiello, Ciro, Milano, Aldo, Mondino, Michele, Moreo, Antonella Maurizia, Mortara, Andrea, Murrone, Adriano, Palmieri, Vittorio, Pelenghi, Stefano, Pini, Daniela, Pistono, Massimo, Porcu, Maurizio, Potena, Luciano, Rinaldi, Mauro, Romanò, Massimo, Roncon, Loris, Rossini, Roberta, Russo, Claudio Francesco, Scotto di Uccio, Fortunato, Urbinati, Stefano, Zecchin, Massimo, Caldarola, Pasquale, Oliveti, Alessandra, Frigerio, Maria, Musumeci, Francesco, Gulizia, Michele Massimo, Oliva, Fabrizio, Gabrielli, Domenico, and Colivicchi, Furio

Subjects
Heart Failure, Cardiotonic Agents, Advanced heart failure, Heart transplantation, Ventricular assist device, Critical Pathways, Humans, Palliative Care, Heart Transplantation, Heart-Assist Devices
Abstract

Heart failure is a complex clinical syndrome with a severe prognosis, despite therapeutic progress. The management of the advanced stages of the syndrome is particularly complex in patients who are referred to palliative care as well as in those who are candidates for cardiac replacement therapy. For the latter group, a prompt recognition of the transition to the advanced stage as well as an early referral to the centers for cardiac replacement therapy are essential elements to ensure that patients follow the most appropriate diagnostic-therapeutic pathway. The aim of this document is to focus on the main diagnostic and therapeutic aspects related to the advanced stages of heart failure and, in particular, on the management of patients who are candidates for cardiac replacement therapy.

Published
2022

44. ANMCO position paper on antithrombotic treatment of patients with atrial fibrillation undergoing intracoronary stenting and/or acute coronary syndromes

Author

De Luca, Leonardo, primary, Rubboli, Andrea, additional, Lettino, Maddalena, additional, Tubaro, Marco, additional, Leonardi, Sergio, additional, Casella, Gianni, additional, Valente, Serafina, additional, Rossini, Roberta, additional, Sciahbasi, Alessandro, additional, Natale, Enrico, additional, Trambaiolo, Paolo, additional, Navazio, Alessandro, additional, Cipriani, Manlio, additional, Corda, Marco, additional, De Nardo, Alfredo, additional, Francese, Giuseppina Maura, additional, Napoletano, Cosimo, additional, Tizzani, Emanuele, additional, Nardi, Federico, additional, Roncon, Loris, additional, Caldarola, Pasquale, additional, Riccio, Carmine, additional, Gabrielli, Domenico, additional, Oliva, Fabrizio, additional, Massimo Gulizia, Michele, additional, and Colivicchi, Furio, additional

Published
2022
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49. Characteristics and Outcomes of Patients With ST-Segment Elevation Myocardial Infarction Excluded from the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) Trial

Author

Fiocca, Luigi, Guagliumi, Giulio, Rossini, Roberta, Parise, Helen, Musumeci, Giuseppe, Sirbu, Vasile, Lortkipanidze, Nikoloz, Yu, Jennifer, Mihalcsik, Laurian, Vassileva, Angelina, Valsecchi, Orazio, Gavazzi, Antonello, Mehran, Roxana, and Stone, Gregg W.

Published
2013
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50. Aspirin Desensitization in Patients With Coronary Artery Disease: Results of the Multicenter ADAPTED Registry (Aspirin Desensitization in Patients With Coronary Artery Disease)

Author

Rossini, Roberta, Iorio, Annamaria, Pozzi, Roberto, Bianco, Matteo, Musumeci, Giuseppe, Leonardi, Sergio, Lettieri, Corrado, Bossi, Irene, Colombo, Paola, Rigattieri, Stefano, Dossena, Cinzia, Anzuini, Angelo, Capodanno, Davide, Senni, Michele, and Angiolillo, Dominick J.

Published
2017
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