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Magnetic resonance imaging (MRI) plays a significant role in the routine imaging workflow, providing both anatomical and functional information. 19F MRI is an evolving imaging modality where instead of 1H, 19F nuclei are excited. As the signal from endogenous 19F in the body is negligible, exogenous 19F signals obtained by 19F radiofrequency coils are exceptionally specific. Highly fluorinated agents targeting particular biological processes (i.e., the presence of immune cells) have been visualised using 19F MRI, highlighting its potential for non-invasive and longitudinal molecular imaging. This article aims to provide both a broad overview of the various applications of 19F MRI, with cancer imaging as a focus, as well as a practical guide to 19F imaging. We will discuss the essential elements of a 19F system and address common pitfalls during acquisition. Last but not least, we will highlight future perspectives that will enhance the role of this modality. While not an exhaustive exploration of all 19F literature, we endeavour to encapsulate the broad themes of the field and introduce the world of 19F molecular imaging to newcomers. 19F MRI bridges several domains, imaging, physics, chemistry, and biology, necessitating multidisciplinary teams to be able to harness this technology effectively. As further technical developments allow for greater sensitivity, we envision that 19F MRI can help unlock insight into biological processes non-invasively and longitudinally.

6G, in contrast to previous generations, is transformative and will revolutionize the wireless evolution from “connected things” to “connected intelligence.” 6G will be rather a convergence of the following four applications that will drive the 6G revolution: (i) multisensory extended reality (XR), (ii) connected robotics and autonomous systems, (iii) wireless brain-computer interaction, and (iv) blockchain and distributed ledger technologies. In this doctoral thesis, we elaborate on how the Internet of No Things and its underlying human-intended services may serve as a step toward realizing the 6G far-reaching network vision. The Internet of No Things aims at ushering in the 6G post-smartphone era, where smart wearables are increasingly replacing the functionalities of smartphones. The transition from the current gadgets-based Internet to the gadget-free Internet of No Things is divided into three phases that start from bearables, move toward wearables, and then finally progress to the last phase, termed nearables. This thesis proposes an architecture for the Internet of No Things that integrates the three evolutionary mobile computing stages of ubiquitous, pervasive, and persuasive computing plus all kind of smart wearables to deliver advanced XR experiences. In addition, we integrate the Ethereum blockchain’s salient features with the emerging field of robonomics and persuasive robotics to solve problems that machines (robots, AIs) cannot solve well alone. To do so, we investigate the widely studied trust game of behavioral economics in a blockchain context by developing a smart contract to propose a networked N-player trust game and the embodied communications enabled by persuasive robots. Next, we introduce the Multiverse architecture to design advanced XR experiences as the anticipated successor of the Metaverse. The Metaverse and Multiverse have in common to realize the fusion of digital and real worlds. However, while the Metaverse primarily focuses on VR an