174 results on '"Roth, B.L."'
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2. Crystal structure of human GPCR Niacin receptor (HCA2)
3. CryoEM structure of Go-coupled NTSR1 with a biased allosteric modulator
4. CryoEM structure of Go-coupled NTSR1
5. Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator
6. Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex
7. Gi bound nociceptin receptor in complex with nociceptin peptide
8. Gi bound mu-opioid receptor in complex with endomorphin
9. Gi bound mu-opioid receptor in complex with beta-endorphin
10. Gi bound delta-opioid receptor in complex with deltorphin
11. Gi bound kappa-opioid receptor in complex with dynorphin
12. CryoEM structure of miniGq-coupled hM3R in complex with Iperoxo
13. CryoEM structure of miniGq-coupled hM3R in complex with iperoxo (local refinement)
14. CryoEM structure of miniGo-coupled hM4Di in complex with DCZ
15. CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22
16. CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16
17. CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382
18. 5-HT2B receptor bound to LSD in complex with beta-arrestin1 obtained by cryo-electron microscopy (cryoEM)
19. 5-HT2B receptor bound to LSD in complex with heterotrimeric mini-Gq protein obtained by cryo-electron microscopy (cryoEM)
20. 5-HT2B receptor bound to LSD obtained by cryo-electron microscopy (cryoEM)
21. Cryo-EM structure of the 5HT2C receptor (VSV isoform) bound to lorcaserin
22. Cryo-EM structure of the 5HT2C receptor (INI isoform) bound to psilocin
23. Cryo-EM structure of the 5HT2C receptor (INI isoform) bound to lorcaserin
24. CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine
25. CryoEM structure of Go-coupled 5-HT5AR in complex with 5-CT
26. CryoEM structure of Go-coupled 5-HT5AR in complex with Lisuride
27. Crystal structure of inactive 5-HT5AR in complex with AS2674723
28. CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
29. CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134
30. CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14
31. Simultaneous, Massively Parallel and Genome-Wide Interrogation of GPCR b-arrestin-ergic Signaling
32. Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein
33. Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein
34. Cryo-EM structure of SKF-81297-bound dopamine receptor 1 in complex with Gs protein
35. Cryo-EM structure of apomorphine-bound dopamine receptor 1 in complex with Gs protein
36. Cryo-EM structure of Bromocriptine-bound dopamine receptor 2 in complex with Gi protein
37. A Structural Understanding of Class B GPCR Selectivity and Activation Revealed
38. A self-activating orphan receptor
39. Virtual discovery of melatonin receptor ligands to modulate circadian rhythms
40. Crystal structure of HTR2A with hallucinogenic agonist
41. Crystal structure of HTR2A with inverse agonist
42. Nanobody-Enabled Monitoring of Kappa Opioid Receptor States
43. How structure informs and transforms chemogenetics
44. Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists
45. Erratum: VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells (Cell (2019) 178(3) (748–761.e17), (S0092867419306221), (10.1016/j.cell.2019.05.051))
46. Structural basis of ligand recognition at the human MT1 melatonin receptor
47. VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells
48. XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity
49. D2 Dopamine Receptor G Protein-Biased Partial Agonists Based on Cariprazine
50. Intraislet glucagon signaling is critical for maintaining glucose homeostasis
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