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123 results on '"Rothmund R"'

1. Endokrine Tumoren des gastroenteropankreatischen Systems

Author

Ahlman, H., Arnold, R., Becker, H. D., Beyer, J., Kisker, O., Klöppel, G., Klose, K. J., Pies, U., Röher, H. D., Rothmund, R., Schneider, S., Simon, B., Simon, D., Stinner, B., Rothmund, M., Teichmann, R. K., Siewert, J. R., editor, Harder, F., editor, and Rothmund, Matthias, editor

Published
2000
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7. Die Lion Studie: Lymphadenektomie beim fortgeschrittenen primären Ovarialkarzinom – Eine multinationale randomisiert-prospektive Studie der AGO

Author

de Gregorio, N, additional, du Bois, A, additional, Sehouli, J, additional, Reuss, A, additional, Burges, A, additional, Kimmig, R, additional, Hilpert, F, additional, Hasenburg, A, additional, Hillemanns, P, additional, Leffern, I, additional, Gropp-Maier, M, additional, Petry, KU, additional, Schindelhauer, A, additional, Rothmund, R, additional, Zivanovic, O, additional, Kullmer, U, additional, Hanf, V, additional, Emons, G, additional, Wager, U, additional, and Harter, P, additional

Published
2018
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13. Optimized generator modes for bipolar vessel sealing

Author

Wagenpfeil, J., primary, Jung, M., additional, Nold, B., additional, Neugebauer, A., additional, Ederer, M., additional, Kramer, B., additional, Rothmund, R., additional, Schwentner, C., additional, Wallwiener, D., additional, Stenzl, A., additional, Schenk, M., additional, Enderle, M., additional, Sawodny, O., additional, and Feuer, R., additional

Published
2015
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14. Finite-element-modeling of egg white as a substitute for tissue coagulation during bipolar radiofrequency-induced thermofusion

Author

Wagenpfeil, J., primary, Schollig, C., additional, Mayer, V., additional, Nold, B., additional, Ederer, M., additional, Neugebauer, A., additional, Rothmund, R., additional, Kramer, B., additional, Schwentner, C., additional, Schenk, M., additional, Wallwiener, D., additional, Stenzl, A., additional, Enderle, M., additional, Sawodny, O., additional, and Feuer, R., additional

Published
2015
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17. A mathematical model of bipolar radiofrequency-induced thermofusion

Author

Wagenpfeil, J., primary, Nold, B., additional, Fischer, K., additional, Neugebauer, A., additional, Rothmund, R., additional, Kramer, B., additional, Brucker, S., additional, Mischinger, J., additional, Schwentner, C., additional, Schenk, M., additional, Wallwiener, D., additional, Stenzl, A., additional, Enderle, M., additional, Sawodny, O., additional, and Ederer, M., additional

Published
2014
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24. Die operative Therapie des Zervixkarzinoms

Author

Taran, F., additional, Henes, M., additional, Rothmund, R., additional, Krämer, B., additional, Becker, S., additional, Rall, K., additional, Wallwiener, M., additional, and Brucker, S., additional

Published
2012
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41. Ist die Mammabiopsie ausreichend finanziert? Eine Prozesskosten & Erlösbetrachtung

Author

Hahn, M., primary, Fischbach, E., additional, Fehm, T., additional, Rothmund, R., additional, Siegmann, K., additional, Scheich, D., additional, Heywang-Koebrunner, S., additional, Jennissen, J., additional, Murauer, M., additional, Krapfl, E., additional, Landwehr, P., additional, Fronhoff, K., additional, Scheler, P., additional, Schreer, I., additional, Solomayer, E., additional, and Wallwiener, D., additional

Published
2010
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45. Efficacy and safety of the novel electrosurgical vessel sealing and cutting instrument BiCision®.

Author

Rothmund R, Kraemer B, Neis F, Brucker S, Wallwiener M, Reda A, Hausch A, Scharpf M, Szyrach MN, Rothmund, Ralf, Kraemer, Bernhard, Neis, Felix, Brucker, Sara, Wallwiener, Markus, Reda, Ali, Hausch, Andrea, Scharpf, Marcus, and Szyrach, Mara Natascha

Abstract

Background: The use of energy-based tissue-sealing and cutting instruments is becoming more and more popular in visceral, urological, and gynecological surgery. For their safe and efficacious use in clinical practice, such instruments have to reliably seal vessels with a minimal sealing failure rate, cause minimal thermal damage to adjacent tissue, and have good cutting qualities.Methods: The efficacy and safety of the novel energy-based instrument for dissection, hemostasis and cutting (BiCision(®), ERBE) was compared to a commercially available device (EnSeal(®), Ethicon Endo-Surgery). We investigated vessel-sealing reliability (success rate), sealing quality and sealing time, lateral thermal damage cutting quality, tissue sticking to the instrument, burst pressure and delayed complications in an acute and chronic pig model after splenectomy, small bowel resection, nephrectomy, salpingo-oophorectomy, and sealing of peripheral vessels.Results: For all parameters investigated, BiCision(®) was at least equivalent to EnSeal(®). BiCision(®) was even superior to EnSeal(®) with respect to the burst pressure in arteries (p = 0.044) and veins (p = 0.023) and the cut quality in all locations (arteries, p = 0.0009; veins, p = 0.043). The course of the 7-day chronic study was uneventful except for one animal that developed an intestinal obstruction. None of the animals showed any signs of postoperative bleeding. On second-look laparotomy at day 7, macroscopic inspection of the sealed tissue and vessels did not show any signs of complications or evidence that bleeding had occurred. Histologically, the integrity of vessel wall fusion, thermal alterations, and inflammatory reactions were comparable, confirming substantial equivalence.Conclusion: We demonstrated that the efficacy and quality of vessel sealing with BiCision(®) is at least equivalent to those of EnSeal(®) for vessel diameters up to 7 mm. Since EnSeal(®) has already been shown to be safe in clinical practice, BiCision(®) should be as reliable as EnSeal(®) under clinical conditions. [ABSTRACT FROM AUTHOR]

Published
2012
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48. Impaired bone microenvironment: correlation between bone density and presence of disseminated tumor cells

Author

Kraemer B, Rothmund R, Banys M, Krawczyk N, Ef, Solomayer, Mack C, Wallwiener D, and Tanja Fehm

Subjects
Adult, Aged, 80 and over, Breast Neoplasms, Middle Aged, Neoplastic Cells, Circulating, Immunohistochemistry, Bone and Bones, Immunophenotyping, Postmenopause, Premenopause, Bone Density, Bone Marrow, Chemotherapy, Adjuvant, Humans, Osteoporosis, Female, Aged
Abstract

Disseminated tumor cells (DTCs) in bone marrow (BM) occur in 30-40% of primary breast cancer patients. An impaired bone microenvironment may lead to reduced bone density and osteoporosis affecting the BM as a homing site for DTCs. The bone mineral density (BMD) and its correlation to DTC in BM was evaluated.One hundred and eighty-one women (70 premenopausal, 111 postmenopausal) underwent quantitative ultrasonometry before adjuvant chemotherapy. BM aspirates were analyzed by immunocytochemistry using the ACIS system (Chromavision) based on immunostaining.DTCs were detected in 39% of the patients. Positive BM status correlated significantly with the nodal status. BMD was significantly reduced in the postmenopausal patients (p=0.003). Smaller tumors and higher BMD correlated significantly (p0.014). Fifty percent of the patients with preclinical osteoporosis were BM positive, whereas 37% with normal or osteopenic BMD had DTCs.An impaired bone micro-environment as found in preclinical osteoporosis might be a homing site for DTCs.

50. Multicenter evaluation of blood-based biomarkers for the detection of endometriosis and adenomyosis: A prospective non-interventional study.

Author

Burghaus S, Drazic P, Wölfler M, Mechsner S, Zeppernick M, Meinhold-Heerlein I, Mueller MD, Rothmund R, Vigano P, Becker CM, Zondervan KT, Beckmann MW, Fasching PA, Berner-Gatz S, Grünewald FS, Hund M, Kastner P, Klammer M, Laubender RP, Wegmeyer H, Wienhues-Thelen UH, and Renner SP

Subjects
Female, Humans, Prospective Studies, ROC Curve, Biomarkers, Endometriosis diagnosis, Adenomyosis diagnosis, Adenomyosis pathology
Abstract

Objective: To evaluate blood-based biomarkers to detect endometriosis and/or adenomyosis across nine European centers (June 2014-April 2018)., Methods: This prospective, non-interventional study assessed the diagnostic accuracy of 54 blood-based biomarker immunoassays in samples from 919 women (aged 18-45 years) with suspicion of endometriosis and/or adenomyosis versus symptomatic controls. Endometriosis was stratified by revised American Society for Reproductive Medicine stage. Symptomatic controls were "pathologic symptomatic controls" or "pathology-free symptomatic controls". The main outcome measure was receiver operating characteristic-area under the curve (ROC-AUC) and Wilcoxon P values corrected for multiple testing (q values)., Results: CA-125 performed best in "all endometriosis cases" versus "all symptomatic controls" (AUC 0.645, 95% confidence interval [CI] 0.600-0.690, q < 0.001) and increased (P < 0.001) with disease stage. In "all endometriosis cases" versus "pathology-free symptomatic controls", S100-A12 performed best (AUC 0.692, 95% CI 0.614-0.769, q = 0.001) followed by CA-125 (AUC 0.649, 95% CI 0.569-0.729, q = 0.021). In "adenomyosis only cases" versus "symptomatic controls" or "pathology-free symptomatic controls", respectively, the top-performing biomarkers were sFRP-4 (AUC 0.615, 95% CI 0.551-0.678, q = 0.045) and S100-A12 (AUC 0.701, 95% CI 0.611-0.792, q = 0.004)., Conclusion: This study concluded that no biomarkers tested could diagnose or rule out endometriosis/adenomyosis with high certainty., (© 2023 The Authors. International Journal of Gynecology & Obstetrics published by John Wiley & Sons Ltd on behalf of International Federation of Gynecology and Obstetrics.)

Published
2024
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