1. Concomitant autoimmunity may be a predictor of more severe stages of endometriosis
- Author
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Vanni Valeria Stella, Villanacci Roberta, Salmeri Noemi, Papaleo Enrico, Delprato Diana, Ottolina Jessica, Rovere-Querini Patrizia, Ferrari Stefano, Viganò Paola, and Candiani Massimo
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Medicine ,Science - Abstract
Abstract Pathogenesis of endometriosis is still unclear and a role of both innate and adaptive immune system has been postulated. Some recent findings have revealed an increased risk to have concomitant autoimmune disease in women with endometriosis, but no study so far has investigated whether this association could affect endometriosis severity and stage. We retrospectively reviewed medical patients’ notes of women with a confirmed diagnosis of endometriosis who referred to our endometriosis outpatient clinic between January 2015 and December 2019. Cases (endometriosis and an autoimmune disease) were matched in a 1:3 ratio by age and study period with controls (endometriosis without history of autoimmunity). At univariate logistic analysis, concomitant autoimmunity (OR 2.63, 95% CI 1.64–4.21, p
- Published
- 2021
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