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3. Aspacytarabine for the treatment of patients with AML unfit for intensive chemotherapy: a phase 2 study

Author

Altman, Jessica K., Zuckerman, Tsila, Koprivnikar, Jamie, McCloskey, James, Kota, Vamsi, Keng, Michael, Frankfurt, Olga, Abaza, Yasmin, Bixby, Dale L., Emadi, Ashkan, Burch, Micah, Bhatnagar, Bhavana, Luger, Selina M., Percival, Mary-Elizabeth, Wolach, Ofir, Craig, Michael, Ganzel, Chezi, Roboz, Gail, Levi, Itai, Gourevitch, Anna, Flaishon, Liat, Tessler, Shoshi, Blumberg, Chen, Gengrinovitch, Stela, Ben Yakar, Ruth, and Rowe, Jacob M.

Published
2023
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4. Measurable residual disease by flow cytometry in acute myeloid leukemia is prognostic, independent of genomic profiling

Author

Ganzel, Chezi, Sun, Zhuoxin, Baslan, Timour, Zhang, Yanming, Gönen, Mithat, Abdel-Wahab, Omar I., Racevskis, Janis, Garrett-Bakelman, Francine, Lowe, Scott W., Fernandez, Hugo F., Ketterling, Rhett, Luger, Selina M., Litzow, Mark, Lazarus, Hillard M., Rowe, Jacob M., Tallman, Martin S., Levine, Ross L., and Paietta, Elisabeth

Published
2022
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5. Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia

Author

Kimura, Shunsuke, Montefiori, Lindsey, Iacobucci, Ilaria, Zhao, Yaqi, Gao, Qingsong, Paietta, Elisabeth M., Haferlach, Claudia, Laird, A. Douglas, Mead, Paul E., Gu, Zhaohui, Stock, Wendy, Litzow, Mark, Rowe, Jacob M., Luger, Selina M., Hunger, Stephen P., Ryland, Georgina L., Schmidt, Breon, Ekert, Paul G., Oshlack, Alicia, Grimmond, Sean M., Rehn, Jacqueline, Breen, James, Yeung, David, White, Deborah L., Aldoss, Ibrahim, Jabbour, Elias J., Pui, Ching-Hon, Meggendorfer, Manja, Walter, Wencke, Kern, Wolfgang, Haferlach, Torsten, Brady, Samuel, Zhang, Jinghui, Roberts, Kathryn G., Blombery, Piers, and Mullighan, Charles G.

Published
2022
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7. Risk classification at diagnosis predicts post-HCT outcomes in intermediate-, adverse-risk, and KMT2A-rearranged AML

Author

Menghrajani, Kamal, Gomez-Arteaga, Alexandra, Madero-Marroquin, Rafael, Zhang, Mei-Jie, Bo-Subait, Khalid, Sanchez, Jonathan, Wang, Hai-Lin, Aljurf, Mahmoud, Assal, Amer, Bacher, Vera Ulrike, Badawy, Sherif M., Bejanyan, Nelli, Bhatt, Vijaya Raj, Bredeson, Christopher, Byrne, Michael, Castillo, Paul, Cerny, Jan, Chhabra, Saurabh, Ciurea, Stefan Octavian, DeFilipp, Zachariah, Farhadfar, Nosha, Gadalla, Shahinaz, Gale, Robert Peter, Ganguly, Siddhartha, Gowda, Lohith, Grunwald, Michael R., Hashmi, Shahrukh, Hildebrandt, Gerhard, Kanakry, Christopher G., Kansagra, Ankit, Khimani, Farhad, Krem, Maxwell, Lazarus, Hillard, Liu, Hongtao, Martino, Rodrigo, Michelis, Fotios V., Nathan, Sunita, Nishihori, Taiga, Olsson, Richard, Reshef, Ran, Rizzieri, David, Rowe, Jacob M., Savani, Bipin N., Seo, Sachiko, Sharma, Akshay, Solh, Melhem, Ustun, Celalettin, Verdonck, Leo F., Hourigan, Christopher, Sandmaier, Brenda, Litzow, Mark, Kebriaei, Partow, Weisdorf, Daniel, Zhang, Yanming, Tallman, Martin S., and Saber, Wael

Published
2022
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10. Tipifarnib as maintenance therapy did not improve disease-free survival in patients with acute myelogenous leukemia at high risk of relapse: Results of the phase III randomized E2902 trial

Author

Luger, Selina M., Wang, Victoria X., Rowe, Jacob M., Litzow, Mark R., Paietta, Elisabeth, Ketterling, Rhett P., Lazarus, Hillard, Rybka, Witold B., Craig, Michael D., Karp, Judith, Cooper, Brenda W., Makary, Adel Z., Kaminer, Lynne S., Appelbaum, Frederick R., Larson, Richard A., and Tallman, Martin S.

Published
2021
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13. Molecular classification improves risk assessment in adult BCR-ABL1–negative B-ALL

Author

Paietta, Elisabeth, Roberts, Kathryn G., Wang, Victoria, Gu, Zhaohui, Buck, Georgina A.N., Pei, Deqing, Cheng, Cheng, Levine, Ross L., Abdel-Wahab, Omar, Cheng, Zhongshan, Wu, Gang, Qu, Chunxu, Shi, Lei, Pounds, Stanley, Willman, Cheryl L., Harvey, Richard, Racevskis, Janis, Barinka, Jan, Zhang, Yanming, Dewald, Gordon W., Ketterling, Rhett P., Alejos, David, Lazarus, Hillard M., Luger, Selina M., Foroni, Letizia, Patel, Bela, Fielding, Adele K., Melnick, Ari, Marks, David I., Moorman, Anthony V., Wiernik, Peter H., Rowe, Jacob M., Tallman, Martin S., Goldstone, Anthony H., Mullighan, Charles G., and Litzow, Mark R.

Published
2021
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15. Survival following allogeneic transplant in patients with myelofibrosis

Author

Gowin, Krisstina, Ballen, Karen, Ahn, Kwang Woo, Hu, Zhen-Huan, Ali, Haris, Arcasoy, Murat O., Devlin, Rebecca, Coakley, Maria, Gerds, Aaron T., Green, Michael, Gupta, Vikas, Hobbs, Gabriela, Jain, Tania, Kandarpa, Malathi, Komrokji, Rami, Kuykendall, Andrew T., Luber, Kierstin, Masarova, Lucia, Michaelis, Laura C., Patches, Sarah, Pariser, Ashley C., Rampal, Raajit, Stein, Brady, Talpaz, Moshe, Verstovsek, Srdan, Wadleigh, Martha, Agrawal, Vaibhav, Aljurf, Mahmoud, Angel Diaz, Miguel, Avalos, Belinda R., Bacher, Ulrike, Bashey, Asad, Beitinjaneh, Amer M., Cerny, Jan, Chhabra, Saurabh, Copelan, Edward, Cutler, Corey S., DeFilipp, Zachariah, Gadalla, Shahinaz M., Ganguly, Siddhartha, Grunwald, Michael R., Hashmi, Shahrukh K., Kharfan-Dabaja, Mohamed A., Kindwall-Keller, Tamila, Kröger, Nicolaus, Lazarus, Hillard M., Liesveld, Jane L., Litzow, Mark R., Marks, David I., Nathan, Sunita, Nishihori, Taiga, Olsson, Richard F., Pawarode, Attaphol, Rowe, Jacob M., Savani, Bipin N., Savoie, Mary Lynn, Seo, Sachiko, Solh, Melhem, Tamari, Roni, Verdonck, Leo F., Yared, Jean A., Alyea, Edwin, Popat, Uday, Sobecks, Ronald, Scott, Bart L., Nakamura, Ryotaro, Mesa, Ruben, and Saber, Wael

Published
2020
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16. Maintenance Tyrosine Kinase Inhibitors Following Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Myelogenous Leukemia: A Center for International Blood and Marrow Transplant Research Study

Author

DeFilipp, Zachariah, Ancheta, Richard, Liu, Ying, Hu, Zhen-Huan, Gale, Robert Peter, Snyder, David, Schouten, Harry C., Kalaycio, Matt, Hildebrandt, Gerhard C., Ustun, Celalettin, Daly, Andrew, Ganguly, Siddhartha, Inamoto, Yoshihiro, Litzow, Mark, Szer, Jeffrey, Savoie, Mary Lynn, Hossain, Nasheed, Kharfan-Dabaja, Mohamed A., Hamadani, Mehdi, Reshef, Ran, Bajel, Ashish, Schultz, Kirk R., Gadalla, Shahinaz, Gerds, Aaron, Liesveld, Jane, Juckett, Mark B., Kamble, Rammurti, Hashmi, Shahrukh, Abdel-Azim, Hisham, Solh, Melhem, Bacher, Ulrike, Lazarus, Hillard, Olsson, Richard, Cahn, Jean-Yves, Grunwald, Michael R., Savani, Bipin N., Yared, Jean, Rowe, Jacob M., Cerny, Jan, Chaudhri, Naeem A., Aljurf, Mahmoud, Beitinjaneh, Amer, Seo, Sachiko, Nishihori, Taiga, Hsu, Jack W., Ramanathan, Muthalagu, Alyea, Edwin, Popat, Uday, Sobecks, Ronald, and Saber, Wael

Published
2020
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17. International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia.

Author

Gökbuget, Nicola, Dombret, Hervè, Ribera, Jose-Maria, Fielding, Adele K, Advani, Anjali, Bassan, Renato, Chia, Victoria, Doubek, Michael, Giebel, Sebastian, Hoelzer, Dieter, Ifrah, Norbert, Katz, Aaron, Kelsh, Michael, Martinelli, Giovanni, Morgades, Mireia, O'Brien, Susan, Rowe, Jacob M, Stieglmaier, Julia, Wadleigh, Martha, and Kantarjian, Hagop

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Cancer, Pediatric, Childhood Leukemia, Hematology, Clinical Research, Transplantation, Pediatric Cancer, Rare Diseases, Adolescent, Adult, Aged, Aged, 80 and over, Combined Modality Therapy, Drug Resistance, Neoplasm, Female, Health Care Surveys, Humans, Male, Middle Aged, Philadelphia Chromosome, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Prognosis, Recurrence, Remission Induction, Retreatment, Retrospective Studies, Survival Analysis, Treatment Outcome, Young Adult, Cardiorespiratory Medicine and Haematology, Immunology, Cardiovascular medicine and haematology
Abstract

Adults with relapsed/refractory acute lymphoblastic leukemia have an unfavourable prognosis, which is influenced by disease and patient characteristics. To further evaluate these characteristics, a retrospective analysis of 1,706 adult patients with Ph-negative relapsed/refractory B-precursor acute lymphoblastic leukemia diagnosed between 1990-2013 was conducted using data reflecting the standard of care from 11 study groups and large centers in Europe and the United States. Outcomes included complete remission, overall survival, and realization of stem cell transplantation after salvage treatment. The overall complete remission rate after first salvage was 40%, ranging from 35%-41% across disease status categories (primary refractory, relapsed with or without prior transplant), and was lower after second (21%) and third or greater (11%) salvage. The overall complete remission rate was higher for patients diagnosed from 2005 onward (45%, 95% CI: 39%-50%). One- and three-year survival rates after first, second, and third or greater salvage were 26% and 11%, 18% and 6%, and 15% and 4%, respectively, and rates were 2%-5% higher among patients diagnosed from 2005. Prognostic factors included younger age, longer duration of first remission, and lower white blood cell counts at primary diagnosis. This large dataset can provide detailed reference outcomes for patients with relapsed/refractory Ph-negative B-precursor acute lymphoblastic leukemia. clinicaltrials.gov identifier: 02003612.

Published
2016

18. Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia.

Author

Gu, Zhaohui, Churchman, Michelle, Roberts, Kathryn, Li, Yongjin, Liu, Yu, Harvey, Richard C, McCastlain, Kelly, Reshmi, Shalini C, Payne-Turner, Debbie, Iacobucci, Ilaria, Shao, Ying, Chen, I-Ming, Valentine, Marcus, Pei, Deqing, Mungall, Karen L, Mungall, Andrew J, Ma, Yussanne, Moore, Richard, Marra, Marco, Stonerock, Eileen, Gastier-Foster, Julie M, Devidas, Meenakshi, Dai, Yunfeng, Wood, Brent, Borowitz, Michael, Larsen, Eric E, Maloney, Kelly, Mattano, Leonard A, Angiolillo, Anne, Salzer, Wanda L, Burke, Michael J, Gianni, Francesca, Spinelli, Orietta, Radich, Jerald P, Minden, Mark D, Moorman, Anthony V, Patel, Bella, Fielding, Adele K, Rowe, Jacob M, Luger, Selina M, Bhatia, Ravi, Aldoss, Ibrahim, Forman, Stephen J, Kohlschmidt, Jessica, Mrózek, Krzysztof, Marcucci, Guido, Bloomfield, Clara D, Stock, Wendy, Kornblau, Steven, Kantarjian, Hagop M, Konopleva, Marina, Paietta, Elisabeth, Willman, Cheryl L, Loh, Mignon L, Hunger, Stephen P, and Mullighan, Charles G

Subjects
NIH 3T3 Cells, Animals, Humans, Mice, Luciferases, Oncogene Proteins, Fusion, Treatment Outcome, Sequence Analysis, RNA, Genomics, Gene Expression Regulation, Leukemic, Gene Rearrangement, Base Sequence, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Histone Deacetylase Inhibitors, Transcriptome, MEF2 Transcription Factors, Genetics, Pediatric Cancer, Cancer, Pediatric, 2.1 Biological and endogenous factors
Abstract

Chromosomal rearrangements are initiating events in acute lymphoblastic leukaemia (ALL). Here using RNA sequencing of 560 ALL cases, we identify rearrangements between MEF2D (myocyte enhancer factor 2D) and five genes (BCL9, CSF1R, DAZAP1, HNRNPUL1 and SS18) in 22 B progenitor ALL (B-ALL) cases with a distinct gene expression profile, the most common of which is MEF2D-BCL9. Examination of an extended cohort of 1,164 B-ALL cases identified 30 cases with MEF2D rearrangements, which include an additional fusion partner, FOXJ2; thus, MEF2D-rearranged cases comprise 5.3% of cases lacking recurring alterations. MEF2D-rearranged ALL is characterized by a distinct immunophenotype, DNA copy number alterations at the rearrangement sites, older diagnosis age and poor outcome. The rearrangements result in enhanced MEF2D transcriptional activity, lymphoid transformation, activation of HDAC9 expression and sensitive to histone deacetylase inhibitor treatment. Thus, MEF2D-rearranged ALL represents a distinct form of high-risk leukaemia, for which new therapeutic approaches should be considered.

Published
2016

19. Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia.

Author

Iacobucci, Ilaria, Li, Yongjin, Roberts, Kathryn G, Dobson, Stephanie M, Kim, Jaeseung C, Payne-Turner, Debbie, Harvey, Richard C, Valentine, Marcus, McCastlain, Kelly, Easton, John, Yergeau, Donald, Janke, Laura J, Shao, Ying, Chen, I-Ming L, Rusch, Michael, Zandi, Sasan, Kornblau, Steven M, Konopleva, Marina, Jabbour, Elias, Paietta, Elisabeth M, Rowe, Jacob M, Pui, Ching-Hon, Gastier-Foster, Julie, Gu, Zhaohui, Reshmi, Shalini, Loh, Mignon L, Racevskis, Janis, Tallman, Martin S, Wiernik, Peter H, Litzow, Mark R, Willman, Cheryl L, McPherson, John D, Downing, James R, Zhang, Jinghui, Dick, John E, Hunger, Stephen P, and Mullighan, Charles G

Subjects
Humans, Receptors, Erythropoietin, Antineoplastic Agents, Amino Acid Sequence, Base Sequence, Gene Order, Mutation, Molecular Sequence Data, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Rare Diseases, Pediatric Cancer, Childhood Leukemia, Hematology, Pediatric, Stem Cell Research, Cancer, Neurosciences, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

Chromosomal rearrangements are a hallmark of acute lymphoblastic leukemia (ALL) and are important ALL initiating events. We describe four different rearrangements of the erythropoietin receptor gene EPOR in Philadelphia chromosome-like (Ph-like) ALL. All of these rearrangements result in truncation of the cytoplasmic tail of EPOR at residues similar to those mutated in primary familial congenital polycythemia, with preservation of the proximal tyrosine essential for receptor activation and loss of distal regulatory residues. This resulted in deregulated EPOR expression, hypersensitivity to erythropoietin stimulation, and heightened JAK-STAT activation. Expression of truncated EPOR in mouse B cell progenitors induced ALL in vivo. Human leukemic cells with EPOR rearrangements were sensitive to JAK-STAT inhibition, suggesting a therapeutic option in high-risk ALL.

Published
2016

20. Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk

Author

Kimura, Shunsuke, Park, Chun Shik, Montefiori, Lindsey E., Iacobucci, Ilaria, Pölönen, Petri, Gao, Qingsong, Arnold, Elizabeth D., Attarbaschi, Andishe, Brown, Anthony, Buldini, Barbara, Caldwell, Kenneth J., Chang, Yunchao, Chen, Chelsey, Cheng, Cheng, Cheng, Zhongshan, Choi, John, Conter, Valentino, Crews, Kristine R., de Groot-Kruseman, Hester A., Deguchi, Takao, Eguchi, Mariko, Muhle, Hannah E., Elitzur, Sarah, Escherich, Gabriele, Freeman, Burgess B., Gu, Zhaohui, Han, Katie, Horibe, Keizo, Imamura, Toshihiko, Jeha, Sima, Kato, Motohiro, Chiew, Kean H., Khan, Tanya, Kicinski, Michal, Köhrer, Stefan, Kornblau, Steven M., Kotecha, Rishi S., Li, Chi-Kong, Liu, Yen-Chun, Locatelli, Franco, Luger, Selina M., Paietta, Elisabeth M., Manabe, Atsushi, Marquart, Hanne V., Masetti, Riccardo, Maybury, Mellissa, Mazilier, Pauline, Meijerink, Jules P. P., Mitchell, Sharnise, Miyamura, Takako, Moore, Andrew S., Oshima, Koichi, Pawinska-Wasikowska, Katarzyna, Pieters, Rob, Prater, Mollie S., Pruett-Miller, Shondra M., Pui, Ching-Hon, Qu, Chunxu, Reiterova, Michaela, Reyes, Noemi, Roberts, Kathryn G., Rowe, Jacob M., Sato, Atsushi, Schmiegelow, Kjeld, Schrappe, Martin, Shen, Shuhong, Skoczeń, Szymon, Spinelli, Orietta, Stary, Jan, Svaton, Michael, Takagi, Masatoshi, Takita, Junko, Tang, Yanjing, Teachey, David T., Thomas, Paul G., Tomizawa, Daisuke, Trka, Jan, Varotto, Elena, Vincent, Tiffaney L., Yang, Jun J., Yeoh, Allen E. J., Zhou, Yinmei, Zimmermann, Martin, Inaba, Hiroto, Mullighan, Charles G., Kimura, Shunsuke, Park, Chun Shik, Montefiori, Lindsey E., Iacobucci, Ilaria, Pölönen, Petri, Gao, Qingsong, Arnold, Elizabeth D., Attarbaschi, Andishe, Brown, Anthony, Buldini, Barbara, Caldwell, Kenneth J., Chang, Yunchao, Chen, Chelsey, Cheng, Cheng, Cheng, Zhongshan, Choi, John, Conter, Valentino, Crews, Kristine R., de Groot-Kruseman, Hester A., Deguchi, Takao, Eguchi, Mariko, Muhle, Hannah E., Elitzur, Sarah, Escherich, Gabriele, Freeman, Burgess B., Gu, Zhaohui, Han, Katie, Horibe, Keizo, Imamura, Toshihiko, Jeha, Sima, Kato, Motohiro, Chiew, Kean H., Khan, Tanya, Kicinski, Michal, Köhrer, Stefan, Kornblau, Steven M., Kotecha, Rishi S., Li, Chi-Kong, Liu, Yen-Chun, Locatelli, Franco, Luger, Selina M., Paietta, Elisabeth M., Manabe, Atsushi, Marquart, Hanne V., Masetti, Riccardo, Maybury, Mellissa, Mazilier, Pauline, Meijerink, Jules P. P., Mitchell, Sharnise, Miyamura, Takako, Moore, Andrew S., Oshima, Koichi, Pawinska-Wasikowska, Katarzyna, Pieters, Rob, Prater, Mollie S., Pruett-Miller, Shondra M., Pui, Ching-Hon, Qu, Chunxu, Reiterova, Michaela, Reyes, Noemi, Roberts, Kathryn G., Rowe, Jacob M., Sato, Atsushi, Schmiegelow, Kjeld, Schrappe, Martin, Shen, Shuhong, Skoczeń, Szymon, Spinelli, Orietta, Stary, Jan, Svaton, Michael, Takagi, Masatoshi, Takita, Junko, Tang, Yanjing, Teachey, David T., Thomas, Paul G., Tomizawa, Daisuke, Trka, Jan, Varotto, Elena, Vincent, Tiffaney L., Yang, Jun J., Yeoh, Allen E. J., Zhou, Yinmei, Zimmermann, Martin, Inaba, Hiroto, and Mullighan, Charles G.

Published
2024

21. Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia

Author

Oshima, Koichi, Zhao, Junfei, Pérez-Durán, Pablo, Brown, Jessie A., Patiño-Galindo, Juan Angel, Chu, Timothy, Quinn, Aidan, Gunning, Thomas, Belver, Laura, Ambesi-Impiombato, Alberto, Tosello, Valeria, Wang, Zhengqiang, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Balbin, Milagros, Nicolas, Concepcion, Gastier-Foster, Julie M., Devidas, Meenakshi, Loh, Mignon L., Paietta, Elisabeth, Tallman, Martin S., Rowe, Jacob M., Litzow, Mark, Minden, Mark D., Meijerink, Jules, Rabadan, Raul, and Ferrando, Adolfo

Published
2020
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22. In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs.

Author

Tefferi, Ayalew, Kantarjian, Hagop, Rajkumar, S Vincent, Baker, Lawrence H, Abkowitz, Jan L, Adamson, John W, Advani, Ranjana Hira, Allison, James, Antman, Karen H, Bast, Robert C, Bennett, John M, Benz, Edward J, Berliner, Nancy, Bertino, Joseph, Bhatia, Ravi, Bhatia, Smita, Bhojwani, Deepa, Blanke, Charles D, Bloomfield, Clara D, Bosserman, Linda, Broxmeyer, Hal E, Byrd, John C, Cabanillas, Fernando, Canellos, George Peter, Chabner, Bruce A, Chanan-Khan, Asher, Cheson, Bruce, Clarkson, Bayard, Cohn, Susan L, Colon-Otero, Gerardo, Cortes, Jorge, Coutre, Steven, Cristofanilli, Massimo, Curran, Walter J, Daley, George Q, DeAngelo, Daniel J, Deeg, H Joachim, Einhorn, Lawrence H, Erba, Harry P, Esteva, Francisco J, Estey, Elihu, Fidler, Isaiah J, Foran, James, Forman, Stephen, Freireich, Emil, Fuchs, Charles, George, James N, Gertz, Morie A, Giralt, Sergio, Golomb, Harvey, Greenberg, Peter, Gutterman, Jordan, Handin, Robert I, Hellman, Samuel, Hoff, Paulo Marcelo, Hoffman, Ronald, Hong, Waun Ki, Horowitz, Mary, Hortobagyi, Gabriel N, Hudis, Clifford, Issa, Jean Pierre, Johnson, Bruce Evan, Kantoff, Philip W, Kaushansky, Kenneth, Khayat, David, Khuri, Fadlo R, Kipps, Thomas J, Kripke, Margaret, Kyle, Robert A, Larson, Richard A, Lawrence, Theodore S, Levine, Ross, Link, Michael P, Lippman, Scott M, Lonial, Sagar, Lyman, Gary H, Markman, Maurie, Mendelsohn, John, Meropol, Neal J, Messinger, Yoav, Mulvey, Therese M, O'Brien, Susan, Perez-Soler, Roman, Pollock, Raphael, Prchal, Josef, Press, Oliver, Radich, Jerald, Rai, Kanti, Rosenberg, Saul A, Rowe, Jacob M, Rugo, Hope, Runowicz, Carolyn D, Sandmaier, Brenda M, Saven, Alan, Schafer, Andrew I, Schiffer, Charles, Sekeres, Mikkael A, Silver, Richard T, Siu, Lillian L, and Steensma, David P

Subjects
Humans, Neoplasms, Antineoplastic Agents, Patient Advocacy, Patient Participation, Drug Costs, Prescription Fees, United States, Medical and Health Sciences
Published
2015

25. Hematopoietic Cell Transplantation in the Treatment of Adult Acute Lymphoblastic Leukemia: Updated 2019 Evidence-Based Review from the American Society for Transplantation and Cellular Therapy

Author

DeFilipp, Zachariah, Advani, Anjali S., Bachanova, Veronika, Cassaday, Ryan D., Deangelo, Daniel J., Kebriaei, Partow, Rowe, Jacob M., Seftel, Matthew D., Stock, Wendy, Tallman, Martin S., Fanning, Suzanne, Inamoto, Yoshihiro, Kansagra, Ankit, Johnston, Laura, Nagler, Arnon, Sauter, Craig S., Savani, Bipin N., Perales, Miguel-Angel, Carpenter, Paul A., Larson, Richard A., and Weisdorf, Daniel

Published
2019
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30. The impact of the graft-versus-leukemia effect on survival in acute lymphoblastic leukemia

Author

Yeshurun, Moshe, Weisdorf, Daniel, Rowe, Jacob M., Tallman, Martin S., Zhang, Mei-Jie, Wang, Hai-Lin, Saber, Wael, de Lima, Marcos, Sandmaier, Brenda M., Uy, Geoffrey, Kamble, Rammurti T., Cairo, Mitchell S., Cooper, Brenda W., Cahn, Jean-Yves, Ganguly, Siddhartha, Camitta, Bruce, Verdonck, Leo F., Dandoy, Christopher, Diaz, Miguel Angel, Savani, Bipin N., George, Biju, Liesveld, Jane, McGuirk, Joseph, Byrne, Michael, Grunwald, Michael R., Drobyski, William R., Pulsipher, Michael A., Abdel-Azim, Hisham, Prestidge, Tim, Wieduwilt, Matthew J., Martino, Rodrigo, Norkin, Maxim, Beitinjaneh, Amer, Seo, Sachiko, Nishihori, Taiga, Wirk, Baldeep, Frangoul, Haydar, Bashey, Asad, Mori, Shahram, Marks, David I., and Bachanova, Veronika

Published
2019
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31. Single cell dissection of developmental origins and transcriptional heterogeneity in B-cell acute lymphoblastic leukemia

Author

Iacobucci, Ilaria, primary, Zeng, Andy G. X., additional, Gao, Qingsong, additional, Garcia-Prat, Laura, additional, Baviskar, Pradyuamna, additional, Shah, Sayyam, additional, Murison, Alexander James, additional, Voisin, Veronique, additional, Chan-Seng-Yue, Michelle, additional, Cheng, Cheng, additional, Qu, Chunxu, additional, Bailey, Colin, additional, Lear, Matthew, additional, Witkowski, Matthew, additional, Zhou, Xin, additional, Zaldivar Peraza, Airen, additional, Gangwani, Karishma, additional, Advani, Anjali, additional, Luger, Selina M., additional, Litzow, Mark R., additional, Rowe, Jacob M., additional, Paietta, Elisabeth M., additional, Stock, Wendy, additional, Dick, John E., additional, and Mullighan, Charles G, additional

Published
2023
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35. Myeloablative vs reduced-intensity conditioning allogeneic hematopoietic cell transplantation for chronic myeloid leukemia

Author

Chhabra, Saurabh, Ahn, Kwang Woo, Hu, Zhen-Huan, Jain, Sandeep, Assal, Amer, Cerny, Jan, Copelan, Edward A., Daly, Andrew, DeFilipp, Zachariah, Gadalla, Shahinaz M., Gale, Robert Peter, Ganguly, Siddhartha, Hamilton, Betty K., Hildebrandt, Gerhard Carl, Hsu, Jack W., Inamoto, Yoshihiro, Kanate, Abraham S., Khoury, H. Jean, Lazarus, Hillard M., Litzow, Mark R., Nathan, Sunita, Olsson, Richard F., Pawarode, Attaphol, Ringden, Olle, Rowe, Jacob M., Saad, Ayman, Savani, Bipin N., Schouten, Harry C., Seo, Sachiko, Shah, Nirav N., Solh, Melhem, Stuart, Robert K., Ustun, Celalettin, Woolfrey, Ann E., Yared, Jean A., Alyea, Edwin P., Kalaycio, Matt E., Popat, Uday, Sobecks, Ronald M., and Saber, Wael

Published
2018
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38. Biologic and clinical features of childhood gamma delta T-ALL: identification of STAG2/LMO2 γδ T-ALL as an extremely high risk leukemia in the very young

Author

Kimura, Shunsuke, primary, Polonen, Petri, additional, Montefiori, Lindsey, additional, Park, Chun Shik, additional, Iacobucci, Ilaria, additional, Yeoh, Allen EJ, additional, Attarbaschi, Andishe, additional, Moore, Andrew S., additional, Brown, Anthony, additional, Manabe, Atsushi, additional, Buldini, Barbara, additional, Freeman, Burgess B., additional, Chen, Chelsey, additional, Cheng, Cheng, additional, Kean Hui, Chiew, additional, Li, Chi-Kong, additional, Pui, Ching-Hon, additional, Qu, Chunxu, additional, Tomizawa, Daisuke, additional, Teachey, David T., additional, Varotto, Elena, additional, M Paietta, Elisabeth, additional, Arnold, Elizabeth D., additional, Locatelli, Franco, additional, Escherich, Gabriele, additional, Elisa Muhle, Hannah, additional, Marquart, Hanne Vibeke, additional, de Groot-Kruseman, Hester A., additional, Rowe, Jacob M, additional, Stary, Jan, additional, Trka, Jan, additional, Choi, John Kim, additional, Meijerink, Jules P.P., additional, Yang, Jun J., additional, Takita, Junko, additional, Pawinska-Wasikowska, Katarzyna, additional, Roberts, Kathryn G., additional, Han, Katie, additional, Caldwell, Kenneth J., additional, Schmiegelow, Kjeld, additional, Crews, Kristine R., additional, Eguchi, Mariko, additional, Schrappe, Martin, additional, Zimmerman, Martin, additional, Takagi, Masatoshi, additional, Maybury, Mellissa, additional, Svaton, Michael, additional, Reiterova, Michaela, additional, Kicinski, Michal, additional, Prater, Mollie S., additional, Kato, Motohiro, additional, Reyes, Noemi, additional, Spinelli, Orietta, additional, Thomas, Paul, additional, Mazilier, Pauline, additional, Gao, Qingsong, additional, Masetti, Riccardo, additional, Kotecha, Rishi S, additional, Pieters, Rob, additional, Elitzur, Sarah, additional, Luger, Selina M., additional, Mitchell, Sharnise, additional, Pruett-Miller, Shondra M., additional, Shen, Shuhong, additional, Jeha, Sima, additional, Kohrer, Stefan, additional, Kornblau, Steven M, additional, Skoczen, Szymon, additional, Miyamura, Takako, additional, Vincent, Tiffaney L, additional, Imamura, Toshihiko, additional, Conter, Valentino, additional, Tang, Yanjing, additional, Liu, Yen-Chun, additional, Chang, Yunchao, additional, Gu, Zhaohui, additional, Cheng, Zhongshan, additional, Yinmei, Zhou, additional, Inaba, Hiroto, additional, and Mullighan, Charles G., additional

Published
2023
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41. Independent Prognostic Significance of Monosomy 17 and Impact of Karyotype Complexity in Monosomal Karyotype/Complex Karyotype Acute Myeloid Leukemia: Results from Four ECOG-ACRIN Prospective Therapeutic Trials

Author

Strickland, Stephen A, Sun, Zhuoxin, Ketterling, Rhett P, Cherry, Athena M, Cripe, Larry D, Dewald, Gordon, Fernandez, Hugo F, Hicks, Gary A, Higgins, Rodney R, Lazarus, Hillard M, Litzow, Mark R, Luger, Selina M, Paietta, Elisabeth M, Rowe, Jacob M, Vance, Gail H, Wiernik, Peter, Wiktor, Anne E, Zhang, Yanming, and Tallman, Martin S

Published
2017
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42. Allogeneic Hematopoietic Cell Transplantation for Adult Chronic Myelomonocytic Leukemia

Author

Liu, Hien Duong, Ahn, Kwang Woo, Hu, Zhen-Huan, Hamadani, Mehdi, Nishihori, Taiga, Wirk, Baldeep, Beitinjaneh, Amer, Rizzieri, David, Grunwald, Michael R., Sabloff, Mitchell, Olsson, Richard F., Bajel, Ashish, Bredeson, Christopher, Daly, Andrew, Inamoto, Yoshihiro, Majhail, Navneet, Saad, Ayman, Gupta, Vikas, Gerds, Aaron, Malone, Adriana, Tallman, Martin, Reshef, Ran, Marks, David I., Copelan, Edward, Gergis, Usama, Savoie, Mary Lynn, Ustun, Celalettin, Litzow, Mark R., Cahn, Jean-Yves, Kindwall-Keller, Tamila, Akpek, Gorgun, Savani, Bipin N., Aljurf, Mahmoud, Rowe, Jacob M., Wiernik, Peter H., Hsu, Jack W., Cortes, Jorge, Kalaycio, Matt, Maziarz, Richard, Sobecks, Ronald, Popat, Uday, Alyea, Edwin, and Saber, Wael

Published
2017
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43. Determinants of fatal bleeding during induction therapy for acute promyelocytic leukemia in the ATRA era

Author

Mantha, Simon, Goldman, Debra A., Devlin, Sean M., Lee, Ju-Whei, Zannino, Diana, Collins, Marnie, Douer, Dan, Iland, Harry J., Litzow, Mark R., Stein, Eytan M., Appelbaum, Frederick R., Larson, Richard A., Stone, Richard, Powell, Bayard L., Geyer, Susan, Laumann, Kristina, Rowe, Jacob M., Erba, Harry, Coutre, Steven, Othus, Megan, Park, Jae H., Wiernik, Peter H., and Tallman, Martin S.

Published
2017
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44. PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia

Author

Gu, Zhaohui, Churchman, Michelle L., Roberts, Kathryn G., Moore, Ian, Zhou, Xin, Nakitandwe, Joy, Hagiwara, Kohei, Pelletier, Stephane, Gingras, Sebastien, Berns, Hartmut, Payne-Turner, Debbie, Hill, Ashley, Iacobucci, Ilaria, Shi, Lei, Pounds, Stanley, Cheng, Cheng, Pei, Deqing, Qu, Chunxu, Newman, Scott, Devidas, Meenakshi, Dai, Yunfeng, Reshmi, Shalini C., Gastier-Foster, Julie, Raetz, Elizabeth A., Borowitz, Michael J., Wood, Brent L., Carroll, William L., Zweidler-McKay, Patrick A., Rabin, Karen R., Mattano, Leonard A., Maloney, Kelly W., Rambaldi, Alessandro, Spinelli, Orietta, Radich, Jerald P., Minden, Mark D., Rowe, Jacob M., Luger, Selina, Litzow, Mark R., Tallman, Martin S., Racevskis, Janis, Zhang, Yanming, Bhatia, Ravi, Kohlschmidt, Jessica, Mrózek, Krzysztof, Bloomfield, Clara D., Stock, Wendy, Kornblau, Steven, Kantarjian, Hagop M., Konopleva, Marina, Evans, Williams E., Jeha, Sima, Pui, Ching-Hon, Yang, Jun, Paietta, Elisabeth, Downing, James R., Relling, Mary V., Zhang, Jinghui, Loh, Mignon L., Hunger, Stephen P., and Mullighan, Charles G.

Published
2019
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48. Synergistic antileukemic therapies in NOTCH1 -induced T-ALL

Author

Sanchez-Martin, Marta, Ambesi-Impiombato, Alberto, Qin, Yue, Herranz, Daniel, Bansal, Mukesh, Girardi, Tiziana, Paietta, Elisabeth, Tallman, Martin S., Rowe, Jacob M., De Keersmaecker, Kim, Califano, Andrea, and Ferrando, Adolfo A.

Published
2017

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