119 results on '"Rubio, Aileen"'
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2. SAT-339 Sequential administration of siRNA with an mRNA encoding clearance profile associated variants of HBsAg exhibits significant antiviral activity in AAV/HBV mouse model
3. Efficacy of SPR720 in murine models of non-tuberculous mycobacterial pulmonary infection.
4. Dysregulation of mprF and dltABCD expression among daptomycin-non-susceptible MRSA clinical isolates.
5. Therapeutic vaccine candidate CLB-3000 (CLB-405 and CLB-505 adjuvanted with Alhydrogel): a Good Laboratory Practice (GLP)-compliant 15-week intramuscular toxicity study in rabbits with a 4-week recovery
6. A monoclonal antibody 4G2 exhibits anti-viral activity in mouse models of chronic hepatitis B
7. Bioanalysis of Pseudomonas aeruginosa alkyl quinolone signalling molecules in infected mouse tissue using LC–MS/MS; and its application to a pharmacodynamic evaluation of MvfR inhibition
8. In vitroactivity andin vivoefficacy against non-tuberculous mycobacteria of SPR719, the active moiety of the novel oral benzimidazole prodrug SPR720
9. Therapeutic vaccination with CLB-3000 in a mouse model of chronic hepatitis B induces anti-HBs responses associated with functional cure
10. SAT-197 - Therapeutic vaccine candidate CLB-3000 (CLB-405 and CLB-505 adjuvanted with Alhydrogel): a Good Laboratory Practice (GLP)-compliant 15-week intramuscular toxicity study in rabbits with a 4-week recovery
11. SAT-191 - A monoclonal antibody 4G2 exhibits anti-viral activity in mouse models of chronic hepatitis B
12. Zipper-like interaction between proteins in adjacent daughter cells mediates protein localization
13. Elevated levels of ketopantoate hydroxymethyltransferase (PanB) lead to a physiologically significant coenzyme A elevation in Salmonella enterica serovar Typhimurium
14. In Vitro and In Vivo Characterization of Tebipenem, an Oral Carbapenem
15. Evaluation of Antimicrobial Effects of a New Polymyxin Molecule (SPR741) When Tested in Combination with a Series of β-Lactam Agents Against a Challenge Set of Gram-Negative Pathogens
16. Reduced flux through the purine biosynthetic pathway results in an increased requirement for coenzyme A in thiamine synthesis in Salmonella enterica serovar Typhimurium
17. Engulfment-regulated proteolysis of SpoIIQ: evidence that dual checkpoints control σK activity
18. Contributions of protein structure and gene position to the compartmentalization of the regulatory proteins σE and SpoIIE in sporulating Bacillus subtilis
19. Potentiation of Antibiotics against Gram-Negative Bacteria by Polymyxin B Analogue SPR741 from Unique Perturbation of the Outer Membrane
20. Antimicrobial Activity Evaluation of Tebipenem (SPR859), an Orally Available Carbapenem, against a Global Set of Enterobacteriaceae Isolates, Including a Challenge Set of Organisms
21. In Vitro Activity of Tebipenem (SPR859) against Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria
22. In Vitro Susceptibility Testing of a Novel Benzimidazole, SPR719, against Nontuberculous Mycobacteria
23. Localization of translocation complex components in Bacillus subtilis: enrichment of the signal recognition particle receptor at early sporulation septa
24. Shared Platform for Antibiotic Research and Knowledge: A Collaborative Tool to SPARK Antibiotic Discovery
25. Characterization of SPR994, an Orally Available Carbapenem, with Activity Comparable to Intravenously Administered Carbapenems
26. Dysregulation ofmprFanddltABCDexpression among daptomycin-non-susceptible MRSA clinical isolates
27. Frequency and Distribution of Single-Nucleotide Polymorphisms within mprF in Methicillin-Resistant Staphylococcus aureus Clinical Isolates and Their Role in Cross-Resistance to Daptomycin and Host Defense Antimicrobial Peptides
28. Impact of daptomycin resistance onStaphylococcus aureusvirulence
29. Causal Role of Single Nucleotide Polymorphisms within the mprF Gene of Staphylococcus aureus in Daptomycin Resistance
30. Additional Routes to Staphylococcus aureus Daptomycin Resistance as Revealed by Comparative Genome Sequencing, Transcriptional Profiling, and Phenotypic Studies
31. Whole Genome Characterization of the Mechanisms of Daptomycin Resistance in Clinical and Laboratory Derived Isolates of Staphylococcus aureus
32. VraSR Two-Component Regulatory System Contributes to mprF -Mediated Decreased Susceptibility to Daptomycin in In Vivo -Selected Clinical Strains of Methicillin-Resistant Staphylococcus aureus
33. Differential Adaptations of Methicillin-ResistantStaphylococcus aureusto SerialIn VitroPassage in Daptomycin: Evolution of Daptomycin Resistance and Role of Membrane Carotenoid Content and Fluidity
34. In Vitro Cross-Resistance to Daptomycin and Host Defense Cationic Antimicrobial Peptides in Clinical Methicillin-Resistant Staphylococcus aureus Isolates
35. Regulation of mprF by Antisense RNA Restores Daptomycin Susceptibility to Daptomycin-Resistant Isolates of Staphylococcus aureus
36. Analysis of Cell Membrane Characteristics of In Vitro-Selected Daptomycin-Resistant Strains of Methicillin-Resistant Staphylococcus aureus
37. Characterization of a Daptomycin-Nonsusceptible Vancomycin-Intermediate Staphylococcus aureus Strain in a Patient with Endocarditis
38. Impact of daptomycin resistance on Staphylococcus aureus virulence.
39. Septal localization of forespore membrane proteins during engulfment in Bacillus subtilis
40. Frequency and Distribution of Single-Nucleotide Polymorphisms within mprFin Methicillin-Resistant Staphylococcus aureusClinical Isolates and Their Role in Cross-Resistance to Daptomycin and Host Defense Antimicrobial Peptides
41. Additional Routes to Staphylococcus aureus Daptomycin Resistance as Revealed by Comparative Genome Sequencing, Transcriptional Profiling, and Phenotypic Studies.
42. LC-MS/MS characterization of phospholipid content in daptomycin-susceptible and -resistant isolates of Staphylococcus aureus with mutations in mprF.
43. Differential Adaptations of Methicillin-Resistant Staphylococcus aureus to Serial In Vitro Passage in Daptomycin: Evolution of Daptomycin Resistance and Role of Membrane Carotenoid Content and Fluidity.
44. Engulfment-regulated proteolysis of SpoIIQ: evidence that dual checkpoints control σK activity.
45. Contributions of protein structure and gene position to the compartmentalization of the regulatory proteins σE and SpoIIE in sporulating Bacillus subtilis.
46. Causal Role of Single Nucleotide Polymorphisms within the mprFGene of Staphylococcus aureusin Daptomycin Resistance
47. VraSR Two-Component Regulatory System Contributes to mprF-Mediated Decreased Susceptibility to Daptomycin in In Vivo-Selected Clinical Strains of Methicillin-Resistant Staphylococcus aureus
48. In VitroCross-Resistance to Daptomycin and Host Defense Cationic Antimicrobial Peptides in Clinical Methicillin-Resistant Staphylococcus aureusIsolates
49. Regulation of mprF by Antisense RNA Restores Daptomycin Susceptibility to Daptomycin-Resistant Isolates of Staphylococcus aureus
50. Regulation of mprFby Antisense RNA Restores Daptomycin Susceptibility to Daptomycin-Resistant Isolates of Staphylococcus aureus
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