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Your search keyword '"Ruddarraju, Radhakrishnamraju"' showing total 5 results
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5 results on '"Ruddarraju, Radhakrishnamraju"'

4. Enantioselective total synthesis of β-zearalenol from (<italic>s</italic>)-propylene oxide.

Author

Kotla, Ravindar, Murugulla, Adharvana Chari, Ruddarraju, Radhakrishnamraju, Aparna, P., Donthabakthuni, Shobha, and Sridhar, Gattu

Subjects
PROPYLENE oxide, ENANTIOSELECTIVE catalysis, ZEARALENONE, MACROLIDE antibiotics, CHEMICAL synthesis, HYDROXYLATION
Abstract

The total synthesis of 14-membered resorcylic acid macrolide, β-zearalenol, was accomplished starting from commercially available enantiomerically pure propylene oxide and methyl 2,4-dihydroxy-6-methylbenzoate using Grignard reaction, asymmetric dihydroxylation, Yamaguchi macrolactonization, and ring-closing metathesis as key steps. [ABSTRACT FROM AUTHOR]

Published
2018
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5. Efficient Synthesis of Pyrrolo [2,3-d] Pyrimidines Containing 1,4-Disubstituted-1,2,3-Triazole Derivatives.

Author

Ruddarraju, Radhakrishnamraju, Murugulla, Adharvana Chari, Donthabakthuni, Shobha, Kotla, Ravindar, Deshmukh, Sandeep, Maroju, Ravichandar, and Palle, Sadhanandam

Subjects
*TRIAZOLE derivatives, *PYRIMIDINE synthesis, *SUBSTITUTION reactions, *CHEMICAL yield, *MASS spectrometry
Abstract

Here, we demonstrate a simple but highly efficient method for the synthesis of multifunctionalized pyrrolo[2,3-d]pyrimidines containing 1,4-disubstituted 1,2,3-triazole derivative coupled with various amines ( 10a, 10b, 10c, 10d, 10e, 10f, 10g) and alcohol ( 10h) to obtain final compounds ( 11a, 11b, 11c, 11d, 11e, 11f, 11g, 11h) with reasonable to excellent yields (25% to 94%). The newly synthesized compounds were characterized by IR, 1HNMR, 13CNMR, and mass spectroscopy analysis. [ABSTRACT FROM AUTHOR]

Published
2017
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