761 results on '"Rudnai, Peter"'
Search Results
2. Age at start of using tobacco on the risk of head and neck cancer: Pooled analysis in the International Head and Neck Cancer Epidemiology Consortium (INHANCE)
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Chang, Chun-Pin, Chang, Shen-Chih, Chuang, Shu-Chun, Berthiller, Julien, Ferro, Gilles, Matsuo, Keitaro, Wünsch-Filho, Victor, Toporcov, Tatiana N, de Carvalho, Marcos Brasilino, La Vecchia, Carlo, Olshan, Andrew F, Zevallos, Jose P, Serraino, Diego, Muscat, Joshua, Sturgis, Erich M, Li, Guojun, Morgenstern, Hal, Levi, Fabio, Dal Maso, Luigino, Smith, Elaine, Kelsey, Karl, McClean, Michael, Vaughan, Thomas L, Lazarus, Philip, Ramroth, Heribert, Chen, Chu, Schwartz, Stephen M, Winn, Deborah M, Bosetti, Cristina, Edefonti, Valeria, Garavello, Werner, Negri, Eva, Hayes, Richard B, Purdue, Mark P, Boccia, Stefania, Cadoni, Gabriella, Shangina, Oxana, Koifman, Rosalina, Curado, Maria Paula, Vilensky, Marta, Swiatkowska, Beata, Herrero, Rolando, Franceschi, Silvia, Benhamou, Simone, Fernandez, Leticia, Menezes, Ana MB, Daudt, Alexander W, Mates, Dana, Schantz, Stimson, Yu, Guo-Pei, Lissowska, Jolanta, Brenner, Hermann, Fabianova, Eleonora, Rudnai, Peter, Brennan, Paul, Boffetta, Paolo, Zhang, Zuo-Feng, Hashibe, Mia, and Lee, Yuan-Chin Amy
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Biomedical and Clinical Sciences ,Epidemiology ,Health Services and Systems ,Health Sciences ,Public Health ,Oncology and Carcinogenesis ,Prevention ,Rare Diseases ,Cancer ,Tobacco Smoke and Health ,Dental/Oral and Craniofacial Disease ,Substance Misuse ,Tobacco ,Aetiology ,2.2 Factors relating to the physical environment ,Good Health and Well Being ,Adult ,Age Factors ,Aged ,Case-Control Studies ,Female ,Head and Neck Neoplasms ,Humans ,Male ,Middle Aged ,Risk Factors ,Nicotiana ,Age at start of tobacco use ,Head and neck cancer ,Oral cancer ,Oropharyngeal cancer ,Hypopharyngeal cancer ,Laryngeal cancer ,Public Health and Health Services ,Oncology & Carcinogenesis ,Oncology and carcinogenesis - Abstract
BackgroundTobacco use is a well-established risk factor for head and neck cancer (HNC). However, less is known about the potential impact of exposure to tobacco at an early age on HNC risk.MethodsWe analyzed individual-level data on ever tobacco smokers from 27 case-control studies (17,146 HNC cases and 17,449 controls) in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using random-effects logistic regression models.ResultsWithout adjusting for tobacco packyears, we observed that younger age at starting tobacco use was associated with an increased HNC risk for ever smokers (OR
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- 2019
3. Joint effects of intensity and duration of cigarette smoking on the risk of head and neck cancer: A bivariate spline model approach
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Di Credico, Gioia, Edefonti, Valeria, Polesel, Jerry, Pauli, Francesco, Torelli, Nicola, Serraino, Diego, Negri, Eva, Luce, Daniele, Stucker, Isabelle, Matsuo, Keitaro, Brennan, Paul, Vilensky, Marta, Fernandez, Leticia, Curado, Maria Paula, Menezes, Ana, Daudt, Alexander W, Koifman, Rosalina, Wunsch-Filho, Victor, Holcatova, Ivana, Ahrens, Wolfgang, Lagiou, Pagona, Simonato, Lorenzo, Richiardi, Lorenzo, Healy, Claire, Kjaerheim, Kristina, Conway, David I, Macfarlane, Tatiana V, Thomson, Peter, Agudo, Antonio, Znaor, Ariana, Rios, Leonardo F Boaventura, Toporcov, Tatiana N, Franceschi, Silvia, Herrero, Rolando, Muscat, Joshua, Olshan, Andrew F, Zevallos, Jose P, La Vecchia, Carlo, Winn, Deborah M, Sturgis, Erich M, Li, Guojun, Fabianova, Eleonora, Lissowska, Jolanda, Mates, Dana, Rudnai, Peter, Shangina, Oxana, Swiatkowska, Beata, Moysich, Kirsten, Zhang, Zuo-Feng, Morgenstern, Hal, Levi, Fabio, Smith, Elaine, Lazarus, Philip, Bosetti, Cristina, Garavello, Werner, Kelsey, Karl, McClean, Michael, Ramroth, Heribert, Chen, Chu, Schwartz, Stephen M, Vaughan, Thomas L, Zheng, Tongzhang, Menvielle, Gwenn, Boccia, Stefania, Cadoni, Gabriella, Hayes, Richard B, Purdue, Mark, Gillison, Maura, Schantz, Stimson, Yu, Guo-Pei, Brenner, Hermann, D'Souza, Gypsyamber, Gross, Neil D, Chuang, Shu-Chun, Boffetta, Paolo, Hashibe, Mia, Lee, Yuan-Chin Amy, and Dal Maso, Luigino
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Biomedical and Clinical Sciences ,Oncology and Carcinogenesis ,Prevention ,Tobacco Smoke and Health ,Substance Misuse ,Tobacco ,Dental/Oral and Craniofacial Disease ,Rare Diseases ,Cancer ,2.2 Factors relating to the physical environment ,Good Health and Well Being ,Adult ,Aged ,Aged ,80 and over ,Case-Control Studies ,Cigarette Smoking ,Female ,Head and Neck Neoplasms ,Humans ,Male ,Middle Aged ,Risk Factors ,Bivariate spline models ,Cigarette smoking duration ,Cigarette smoking intensity ,Head and neck cancer ,INHANCE ,Laryngeal cancer ,Oral cavity and pharyngeal cancers ,Dentistry ,Public Health and Health Services ,Oncology & Carcinogenesis ,Oncology and carcinogenesis - Abstract
ObjectivesThis study aimed at re-evaluating the strength and shape of the dose-response relationship between the combined (or joint) effect of intensity and duration of cigarette smoking and the risk of head and neck cancer (HNC). We explored this issue considering bivariate spline models, where smoking intensity and duration were treated as interacting continuous exposures.Materials and methodsWe pooled individual-level data from 33 case-control studies (18,260 HNC cases and 29,844 controls) participating in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. In bivariate regression spline models, exposures to cigarette smoking intensity and duration (compared with never smokers) were modeled as a linear piecewise function within a logistic regression also including potential confounders. We jointly estimated the optimal knot locations and regression parameters within the Bayesian framework.ResultsFor oral-cavity/pharyngeal (OCP) cancers, an odds ratio (OR) >5 was reached after 30 years in current smokers of ∼20 or more cigarettes/day. Patterns of OCP cancer risk in current smokers differed across strata of alcohol intensity. For laryngeal cancer, ORs >20 were found for current smokers of ≥20 cigarettes/day for ≥30 years. In former smokers who quit ≥10 years ago, the ORs were approximately halved for OCP cancers, and ∼1/3 for laryngeal cancer, as compared to the same levels of intensity and duration in current smokers.ConclusionReferring to bivariate spline models, this study better quantified the joint effect of intensity and duration of cigarette smoking on HNC risk, further stressing the need of smoking cessation policies.
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- 2019
4. Alcohol and lung cancer risk among never smokers: A pooled analysis from the international lung cancer consortium and the SYNERGY study
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Fehringer, Gordon, Brenner, Darren R, Zhang, Zuo‐Feng, Lee, Yuan‐Chin Amy, Matsuo, Keitaro, Ito, Hidemi, Lan, Qing, Vineis, Paolo, Johansson, Mattias, Overvad, Kim, Riboli, Elio, Trichopoulou, Antonia, Sacerdote, Carlotta, Stucker, Isabelle, Boffetta, Paolo, Brennan, Paul, Christiani, David C, Hong, Yun‐Chul, Landi, Maria Teresa, Morgenstern, Hal, Schwartz, Ann G, Wenzlaff, Angela S, Rennert, Gad, McLaughlin, John R, Harris, Curtis C, Olivo‐Marston, Susan, Orlow, Irene, Park, Bernard J, Zauderer, Marjorie, Dios, Juan M Barros, Raviña, Alberto Ruano, Siemiatycki, Jack, Koushik, Anita, Lazarus, Philip, Fernández‐Somoano, Ana, Tardon, Adonina, Le Marchand, Loic, Brenner, Hermann, Saum, Kai‐Uwe, Duell, Eric J, Andrew, Angeline S, Szeszenia‐Dabrowska, Neonila, Lissowska, Jolanta, Zaridze, David, Rudnai, Peter, Fabianova, Eleonora, Mates, Dana, Foretova, Lenka, Janout, Vladimir, Bencko, Vladimir, Holcatova, Ivana, Pesatori, Angela Cecilia, Consonni, Dario, Olsson, Ann, Straif, Kurt, and Hung, Rayjean J
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Biomedical and Clinical Sciences ,Oncology and Carcinogenesis ,Lung ,Cancer ,Substance Misuse ,Tobacco ,Alcoholism ,Alcohol Use and Health ,Tobacco Smoke and Health ,Prevention ,Lung Cancer ,Cardiovascular ,Stroke ,Respiratory ,Good Health and Well Being ,Aged ,Alcohol Drinking ,Alcoholic Beverages ,Asia ,Case-Control Studies ,Cohort Studies ,Europe ,Female ,Humans ,Lung Neoplasms ,Male ,Middle Aged ,North America ,Risk Factors ,Smoking ,alcohol ,lung cancer ,wine ,beer ,liquor ,Oncology & Carcinogenesis ,Oncology and carcinogenesis - Abstract
It is not clear whether alcohol consumption is associated with lung cancer risk. The relationship is likely confounded by smoking, complicating the interpretation of previous studies. We examined the association of alcohol consumption and lung cancer risk in a large pooled international sample, minimizing potential confounding of tobacco consumption by restricting analyses to never smokers. Our study included 22 case-control and cohort studies with a total of 2548 never-smoking lung cancer patients and 9362 never-smoking controls from North America, Europe and Asia within the International Lung Cancer Consortium (ILCCO) and SYNERGY Consortium. Alcohol consumption was categorized into amounts consumed (grams per day) and also modelled as a continuous variable using restricted cubic splines for potential non-linearity. Analyses by histologic sub-type were included. Associations by type of alcohol consumed (wine, beer and liquor) were also investigated. Alcohol consumption was inversely associated with lung cancer risk with evidence most strongly supporting lower risk for light and moderate drinkers relative to non-drinkers (>0-4.9 g per day: OR = 0.80, 95% CI = 0.70-0.90; 5-9.9 g per day: OR = 0.82, 95% CI = 0.69-0.99; 10-19.9 g per day: OR = 0.79, 95% CI = 0.65-0.96). Inverse associations were found for consumption of wine and liquor, but not beer. The results indicate that alcohol consumption is inversely associated with lung cancer risk, particularly among subjects with low to moderate consumption levels, and among wine and liquor drinkers, but not beer drinkers. Although our results should have no relevant bias from the confounding effect of smoking we cannot preclude that confounding by other factors contributed to the observed associations. Confounding in relation to the non-drinker reference category may be of particular importance.
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- 2017
5. Indoor air pollution, physical and comfort parameters related to schoolchildren's health: Data from the European SINPHONIE study
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Csobod, Éva, Szuppinger, Péter, Prokai, Réka, Farkas, Petur, Fuzi, Cecilia, Cani, Eduart, Draganic, Jasna, Mogyorosy, Eszter Réka, Korac, Zorica, de Oliveira Fernandes, Eduardo, Ventura, Gabriela, Madureira, Joana, Paciência, Inês, Martins, Anabela, Pereira, Ricardo, Ramos, Elisabete, Rudnai, Peter, Páldy, Anna, Dura, Gyula, Beregszászi, Tímea, Vaskövi, Éva, Magyar, Donát, Pándics, Tamás, Remény-Nagy, Zsuzsanna, Szentmihályi, Renáta, Udvardy, Orsolya, Varró, Mihály J., Kephalopoulos, Stylianos, Kotzias, Dimitrios, Barrero-Moreno, Josefa, Mehmeti, Rahmije, Vilic, Aida, Maestro, Daniel, Moshammer, Hanns, Strasser, Gabriela, Brigitte, Piegler, Hohenblum, Philipp, Goelen, Eddy, Stranger, Marianne, Spruy, Maarten, Sidjimov, Momchil, Hadjipanayis, Adamos, Katsonouri-Sazeides, Andromachi, Demetriou, Eleni, Kubinova, Ruzana, Kazmarová, Helena, Dlouha, Beatricia, Kotlík, Bohumil, Vabar, Helen, Ruut, Juri, Metus, Meelis, Rand, Kristiina, Järviste, Antonina, Nevalainen, Aino, Hyvarinen, Anne, Täubel, Martin, Järvi, Kati, Annesi-Maesano, Isabella, Mandin, Corinne, Berthineau, Bruno, Moriske, Heinz-Joern, Giacomini, Marcia, Neumann, Anett, Bartzis, John, Kalimeri, Krystallia, Saraga, Dikaia, Santamouris, Mattheos, Assimakopoulos, Margarita Niki, Asimakopoulos, Vasiliki, Carrer, Paolo, Cattaneo, Andrea, Pulvirenti, Salvatore, Vercelli, Franco, Strangi, Fabio, Omeri, Elida, Piazza, Silvia, D'Alcamo, Andrea, Fanetti, Anna Clara, Sestini, Piersante, Kouri, Magdalini, Viegi, Giovanni, Sarno, Giuseppe, Baldacci, Sandra, Maio, Sara, Cerrai, Sonia, Franzitta, Vincenzo, Bucchieri, Salvatore, Cibella, Fabio, Simoni, Marzia, Neri, Margherita, Martuzevičius, Dainius, Krugly, Edvinas, Montefort, Stephen, Fsadni, Peter, Brewczyński, Piotr Z., Krakowiak, Ewa, Kurek, Jolanta, Kubarek, Elżbieta, Wlazło, Agnieszka, Borrego, Carlos, Alves, Célia, Valente, Joana, Gurzau, Eugen, Rosu, Cristina, Popita, Gabriela, Neamtiu, Iulia, Neagu, Cristina, Norback, Dan, Bluyssen, Phylomena, Bohms, Michel, Van Den Hazel, Peter, Cassee, Flemming, de Bruin, Yuri Bruinen, Bartonova, Alena, Yang, Aileen, Halzlová, Katarína, Jajcaj, Michal, Kániková, Milada, Miklankova, Olga, Vítkivá, Marianna, Jovasević-Stojanovic, Milena, Zivkovic, Marija, Stevanovic, Zarko, Lazovic, Ivan, Stevanovic, Zana, Zivkovic, Zorica, Cerovic, Sofija, Jocic-Stojanovic, Jasmina, Mumovic, Dejan, Tarttelin, Paula, Chatzidiakou, Lia, Chatzidiakou, Evangelia, Dewolf, Marie-Christine, Baloch, Ramen Munir, Maesano, Cara Nichole, Christoffersen, Jens, Banerjee, Soutrik, and Gabriel, Marta
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- 2020
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6. Endotoxin Exposure Associated with Respiratory Health Among European Schoolchildren: The SINPHONIE Study
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Baloch, Ramen Munir, primary, Magyar, Donát, additional, Rudnai, Peter, additional, Pándics, Tamás, additional, Remény-Nagy, Zsuzsanna, additional, Moshammer, Hanns, additional, Leppänen, Hanna, additional, Hyvärinen, Anne, additional, Täubel, Martin, additional, Norback, Dan, additional, Gabriel, Marta, additional, Di Maio, Sara, additional, Baldacci, Sandra, additional, Sarno, Giuseppe, additional, Viegi, Giovanni, additional, Csobod, Eva, additional, de Oliveira Fernandes, Eduardo, additional, Annesi-Maesano, Isabella, additional, and Consortium, SINPHONIE, additional
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- 2024
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7. Low frequency of cigarette smoking and the risk of head and neck cancer in the INHANCE consortium pooled analysis
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Berthiller, Julien, Straif, Kurt, Agudo, Antonio, Ahrens, Wolfgang, dos Santos, Alexandre Bezerra, Boccia, Stefania, Cadoni, Gabriella, Canova, Cristina, Castellsague, Xavier, Chen, Chu, Conway, David, Curado, Maria Paula, Dal Maso, Luigino, Daudt, Alexander W, Fabianova, Eleonora, Fernandez, Leticia, Franceschi, Silvia, Fukuyama, Erica E, Hayes, Richard B, Healy, Claire, Herrero, Rolando, Holcatova, Ivana, Kelsey, Karl, Kjaerheim, Kristina, Koifman, Sergio, Lagiou, Pagona, La Vecchia, Carlo, Lazarus, Philip, Levi, Fabio, Lissowska, Jolanta, Macfarlane, Tatiana, Mates, Dana, McClean, Michael, Menezes, Ana, Merletti, Franco, Morgenstern, Hal, Muscat, Joshua, Olshan, Andrew F, Purdue, Mark, Ramroth, Heribert, Rudnai, Peter, Schwartz, Stephen M, Serraino, Diego, Shangina, Oxana, Smith, Elaine, Sturgis, Erich M, Szeszenia-Dabrowska, Neonila, Thomson, Peter, Vaughan, Thomas L, Vilensky, Marta, Wei, Qingyi, Winn, Deborah M, Wünsch-Filho, Victor, Zhang, Zuo-Feng, Znaor, Ariana, Ferro, Gilles, Brennan, Paul, Boffetta, Paolo, Hashibe, Mia, and Lee, Yuan-Chin Amy
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Cancer ,Prevention ,Dental/Oral and Craniofacial Disease ,Tobacco Smoke and Health ,Substance Misuse ,Clinical Research ,Rare Diseases ,Tobacco ,Respiratory ,Good Health and Well Being ,Adult ,Aged ,Alcohol Drinking ,Case-Control Studies ,Cigarette Smoking ,Female ,Head and Neck Neoplasms ,Humans ,Logistic Models ,Male ,Middle Aged ,Odds Ratio ,Public Health ,Risk Factors ,Head and neck cancer ,low frequency cigarette smoking ,risk factors ,pooled analysis ,Statistics ,Public Health and Health Services ,Epidemiology - Abstract
BackgroundCigarette smoking is a major risk factor for head and neck cancer (HNC). To our knowledge, low cigarette smoking (0-3, >3-5, >5-10 cigarettes per day.ResultsSmoking >0-3 cigarettes per day was associated with a 50% increased risk of HNC in the study population [odds ratio (OR) = 1.52, 95% confidence interval (CI): (1.21, 1.90). Smoking >3-5 cigarettes per day was associated in each subgroup from OR = 2.01 (95% CI: 1.22, 3.31) among never alcohol drinkers to OR = 2.74 (95% CI: 2.01, 3.74) among women and in each cancer site, particularly laryngeal cancer (OR = 3.48, 95% CI: 2.40, 5.05). However, the observed increased risk of HNC for low smoking frequency was not found among smokers with smoking duration shorter than 20 years.ConclusionOur results suggest a public health message that low frequency of cigarette consumption contributes to the development of HNC. However, smoking duration seems to play at least an equal or a stronger role in the development of HNC.
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- 2016
8. Relation of allium vegetables intake with head and neck cancers: Evidence from the INHANCE consortium
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Galeone, Carlotta, Turati, Federica, Zhang, Zuo-Feng, Guercio, Valentina, Tavani, Alessandra, Serraino, Diego, Brennan, Paul, Fabianova, Eleonora, Lissowska, Jola, Mates, Dana, Rudnai, Peter, Shangina, Oxana, Szeszenia-Dabrowska, Neonila, Vaughan, Thomas L, Kelsey, Karl, McClean, Michael, Levi, Fabio, Hayes, Richard B, Purdue, Mark P, Bosetti, Cristina, Brenner, Hermann, Pelucchi, Claudio, Lee, Yuan-Chin Amy, Hashibe, Mia, Boffetta, Paolo, and La Vecchia, Carlo
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Biomedical and Clinical Sciences ,Nutrition and Dietetics ,Rare Diseases ,Dental/Oral and Craniofacial Disease ,Cancer ,Allium ,Case-Control Studies ,Diet ,Head and Neck Neoplasms ,Humans ,Logistic Models ,Risk Factors ,Vegetables ,Allium vegetables ,Garlic ,Onion ,Food Sciences ,Public Health and Health Services ,Food Science ,Nutrition & Dietetics ,Food sciences ,Nutrition and dietetics - Abstract
ScopeOnly a few studies analyzed the role of allium vegetables with reference to head and neck cancers (HNC), with mixed results. We investigated the potential favorable role of garlic and onion within the International Head and Neck Cancer Epidemiology (INHANCE) Consortium.Methods and resultsWe analyzed pooled individual-level data from eight case-control studies, including 4590 cases and 7082 controls. We estimated odds ratios (ORs) and 95% confidence intervals (CIs) for associations between garlic and onion intakes and HNC risk. Compared with no or low garlic use, the ORs of HNC were 0.95 (95% CI 0.71-1.27) for intermediate and 0.74 (95% CI 0.55-0.99) for high garlic use (p for trend = 0.02). The ORs of HNC for increasing categories of onion intake were 0.91 (95% CI 0.68-1.21) for >1 to ≤3 portions per week, and 0.83 (95% CI 0.60-1.13) for >3 portions per week (p for trend = 0.02), as compared to
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- 2015
9. Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case‐control studies from 27 countries
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Conway, David I, Brenner, Darren R, McMahon, Alex D, Macpherson, Lorna MD, Agudo, Antonio, Ahrens, Wolfgang, Bosetti, Cristina, Brenner, Hermann, Castellsague, Xavier, Chen, Chu, Curado, Maria Paula, Curioni, Otávio A, Dal Maso, Luigino, Daudt, Alexander W, de Gois Filho, José F, D'Souza, Gypsyamber, Edefonti, Valeria, Fabianova, Eleonora, Fernandez, Leticia, Franceschi, Silvia, Gillison, Maura, Hayes, Richard B, Healy, Claire M, Herrero, Rolando, Holcatova, Ivana, Jayaprakash, Vijayvel, Kelsey, Karl, Kjaerheim, Kristina, Koifman, Sergio, La Vecchia, Carlo, Lagiou, Pagona, Lazarus, Philip, Levi, Fabio, Lissowska, Jolanta, Luce, Daniele, Macfarlane, Tatiana V, Mates, Dana, Matos, Elena, McClean, Michael, Menezes, Ana M, Menvielle, Gwenn, Merletti, Franco, Morgenstern, Hal, Moysich, Kirsten, Müller, Heiko, Muscat, Joshua, Olshan, Andrew F, Purdue, Mark P, Ramroth, Heribert, Richiardi, Lorenzo, Rudnai, Peter, Schantz, Stimson, Schwartz, Stephen M, Shangina, Oxana, Simonato, Lorenzo, Smith, Elaine, Stucker, Isabelle, Sturgis, Erich M, Szeszenia‐Dabrowska, Neonila, Talamini, Renato, Thomson, Peter, Vaughan, Thomas L, Wei, Qingyi, Winn, Deborah M, Wunsch‐Filho, Victor, Yu, Guo‐Pei, Zhang, Zuo‐Feng, Zheng, Tongzhang, Znaor, Ariana, Boffetta, Paolo, Chuang, Shu‐Chun, Ghodrat, Marianoosh, Lee, Yuan‐Chin Amy, Hashibe, Mia, and Brennan, Paul
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Behavioral and Social Science ,Tobacco ,Dental/Oral and Craniofacial Disease ,Tobacco Smoke and Health ,Cancer ,Prevention ,Substance Misuse ,Basic Behavioral and Social Science ,Reduced Inequalities ,Good Health and Well Being ,Alcohol Drinking ,Case-Control Studies ,Education ,Female ,Follow-Up Studies ,Global Health ,Head and Neck Neoplasms ,Humans ,Income ,Male ,Meta-Analysis as Topic ,Middle Aged ,Prognosis ,Risk Factors ,Smoking ,Socioeconomic Factors ,head and neck cancer ,socioeconomic inequalities ,epidemiology ,Oncology and Carcinogenesis ,Oncology & Carcinogenesis - Abstract
Low socioeconomic status has been reported to be associated with head and neck cancer risk. However, previous studies have been too small to examine the associations by cancer subsite, age, sex, global region and calendar time and to explain the association in terms of behavioral risk factors. Individual participant data of 23,964 cases with head and neck cancer and 31,954 controls from 31 studies in 27 countries pooled with random effects models. Overall, low education was associated with an increased risk of head and neck cancer (OR = 2.50; 95% CI = 2.02 - 3.09). Overall one-third of the increased risk was not explained by differences in the distribution of cigarette smoking and alcohol behaviors; and it remained elevated among never users of tobacco and nondrinkers (OR = 1.61; 95% CI = 1.13 - 2.31). More of the estimated education effect was not explained by cigarette smoking and alcohol behaviors: in women than in men, in older than younger groups, in the oropharynx than in other sites, in South/Central America than in Europe/North America and was strongest in countries with greater income inequality. Similar findings were observed for the estimated effect of low versus high household income. The lowest levels of income and educational attainment were associated with more than 2-fold increased risk of head and neck cancer, which is not entirely explained by differences in the distributions of behavioral risk factors for these cancers and which varies across cancer sites, sexes, countries and country income inequality levels.
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- 2015
10. Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium
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Toporcov, Tatiana Natasha, Znaor, Ariana, Zhang, Zuo-Feng, Yu, Guo-Pei, Winn, Deborah M, Wei, Qingyi, Vilensky, Marta, Vaughan, Thomas, Thomson, Peter, Talamini, Renato, Szeszenia-Dabrowska, Neonila, Sturgis, Erich M, Smith, Elaine, Shangina, Oxana, Schwartz, Stephen M, Schantz, Stimson, Rudnai, Peter, Richiardi, Lorenzo, Ramroth, Heribert, Purdue, Mark P, Olshan, Andrew F, Eluf-Neto, José, Muscat, Joshua, Moyses, Raquel Ajub, Morgenstern, Hal, Menezes, Ana, McClean, Michael, Matsuo, Keitaro, Mates, Dana, Macfarlane, Tatiana V, Lissowska, Jolanta, Levi, Fabio, Lazarus, Philip, La Vecchia, Carlo, Lagiou, Pagona, Koifman, Sergio, Kjaerheim, Kristina, Kelsey, Karl, Holcatova, Ivana, Herrero, Rolando, Healy, Claire, Hayes, Richard B, Franceschi, Silvia, Fernandez, Leticia, Fabianova, Eleonora, Daudt, Alexander W, Curioni, Otávio Alberto, Maso, Luigino Dal, Curado, Maria Paula, Conway, David I, Chen, Chu, Castellsague, Xavier, Canova, Cristina, Cadoni, Gabriella, Brennan, Paul, Boccia, Stefania, Antunes, José Leopoldo Ferreira, Ahrens, Wolfgang, Agudo, Antonio, Boffetta, Paolo, Hashibe, Mia, Lee, Yuan-Chin Amy, and Filho, Victor Wünsch
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Prevention ,Cancer ,Clinical Research ,Tobacco ,Tobacco Smoke and Health ,Dental/Oral and Craniofacial Disease ,Rare Diseases ,Digestive Diseases ,Aging ,Good Health and Well Being ,Adult ,Age Factors ,Alcohol Drinking ,Case-Control Studies ,Female ,Genetic Predisposition to Disease ,Head and Neck Neoplasms ,Humans ,Incidence ,Male ,Middle Aged ,Odds Ratio ,Registries ,Risk Factors ,Sex Factors ,Smoking ,Head and neck neoplasms ,adult ,smoking ,alcohol drinking ,diet ,Statistics ,Public Health and Health Services ,Epidemiology - Abstract
BackgroundIncreasing incidence of head and neck cancer (HNC) in young adults has been reported. We aimed to compare the role of major risk factors and family history of cancer in HNC in young adults and older patients.MethodsWe pooled data from 25 case-control studies and conducted separate analyses for adults ≤ 45 years old ('young adults', 2010 cases and 4042 controls) and >45 years old ('older adults', 17700 cases and 22 704 controls). Using logistic regression with studies treated as random effects, we estimated adjusted odds ratios (ORs) and 95% confidence intervals (CIs).ResultsThe young group of cases had a higher proportion of oral tongue cancer (16.0% in women; 11.0% in men) and unspecified oral cavity / oropharynx cancer (16.2%; 11.1%) and a lower proportion of larynx cancer (12.1%; 16.6%) than older adult cases. The proportions of never smokers or never drinkers among female cases were higher than among male cases in both age groups. Positive associations with HNC and duration or pack-years of smoking and drinking were similar across age groups. However, the attributable fractions (AFs) for smoking and drinking were lower in young when compared with older adults (AFs for smoking in young women, older women, young men and older men, respectively, = 19.9% (95% CI=9.8%, 27.9%), 48.9% (46.6%, 50.8%), 46.2% (38.5%, 52.5%), 64.3% (62.2%, 66.4%); AFs for drinking=5.3% (-11.2%, 18.0%), 20.0% (14.5%, 25.0%), 21.5% (5.0%, 34.9%) and 50.4% (46.1%, 54.3%). A family history of early-onset cancer was associated with HNC risk in the young [OR=2.27 (95% CI=1.26, 4.10)], but not in the older adults [OR=1.10 (0.91, 1.31)]. The attributable fraction for family history of early-onset cancer was 23.2% (8.60% to 31.4%) in young compared with 2.20% (-2.41%, 5.80%) in older adults.ConclusionsDifferences in HNC aetiology according to age group may exist. The lower AF of cigarette smoking and alcohol drinking in young adults may be due to the reduced length of exposure due to the lower age. Other characteristics, such as those that are inherited, may play a more important role in HNC in young adults compared with older adults.
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- 2015
11. Adult height and head and neck cancer: a pooled analysis within the INHANCE Consortium
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Leoncini, Emanuele, Ricciardi, Walter, Cadoni, Gabriella, Arzani, Dario, Petrelli, Livia, Paludetti, Gaetano, Brennan, Paul, Luce, Daniele, Stucker, Isabelle, Matsuo, Keitaro, Talamini, Renato, La Vecchia, Carlo, Olshan, Andrew F, Winn, Deborah M, Herrero, Rolando, Franceschi, Silvia, Castellsague, Xavier, Muscat, Joshua, Morgenstern, Hal, Zhang, Zuo-Feng, Levi, Fabio, Dal Maso, Luigino, Kelsey, Karl, McClean, Michael, Vaughan, Thomas L, Lazarus, Philip, Purdue, Mark P, Hayes, Richard B, Chen, Chu, Schwartz, Stephen M, Shangina, Oxana, Koifman, Sergio, Ahrens, Wolfgang, Matos, Elena, Lagiou, Pagona, Lissowska, Jolanta, Szeszenia-Dabrowska, Neonila, Fernandez, Leticia, Menezes, Ana, Agudo, Antonio, Daudt, Alexander W, Richiardi, Lorenzo, Kjaerheim, Kristina, Mates, Dana, Betka, Jaroslav, Yu, Guo-Pei, Schantz, Stimson, Simonato, Lorenzo, Brenner, Hermann, Conway, David I, Macfarlane, Tatiana V, Thomson, Peter, Fabianova, Eleonora, Znaor, Ariana, Rudnai, Peter, Healy, Claire, Boffetta, Paolo, Chuang, Shu-Chun, Lee, Yuan-Chin Amy, Hashibe, Mia, and Boccia, Stefania
- Subjects
Tobacco Smoke and Health ,Clinical Research ,Prevention ,Tobacco ,Cancer ,Rare Diseases ,Dental/Oral and Craniofacial Disease ,Good Health and Well Being ,Adult ,Aged ,Alcohol Drinking ,Body Height ,Case-Control Studies ,Educational Status ,Female ,Head and Neck Neoplasms ,Humans ,Incidence ,Interviews as Topic ,Logistic Models ,Male ,Middle Aged ,Odds Ratio ,Overweight ,Risk Factors ,Smoking ,Height ,Consortium ,Head and neck neoplasms ,Public Health and Health Services ,Epidemiology - Abstract
Several epidemiological studies have shown a positive association between adult height and cancer incidence. The only study conducted among women on mouth and pharynx cancer risk, however, reported an inverse association. This study aims to investigate the association between height and the risk of head and neck cancer (HNC) within a large international consortium of HNC. We analyzed pooled individual-level data from 24 case-control studies participating in the International Head and Neck Cancer Epidemiology Consortium. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated separately for men and women for associations between height and HNC risk. Educational level, tobacco smoking, and alcohol consumption were included in all regression models. Stratified analyses by HNC subsites were performed. This project included 17,666 cases and 28,198 controls. We found an inverse association between height and HNC (adjusted OR per 10 cm height = 0.91, 95% CI 0.86-0.95 for men; adjusted OR = 0.86, 95% CI 0.79-0.93 for women). In men, the estimated OR did vary by educational level, smoking status, geographic area, and control source. No differences by subsites were detected. Adult height is inversely associated with HNC risk. As height can be considered a marker of childhood illness and low energy intake, the inverse association is consistent with prior studies showing that HNC occur more frequently among deprived individuals. Further studies designed to elucidate the mechanism of such association would be warranted.
- Published
- 2014
12. No association between global DNA methylation in peripheral blood and lung cancer risk in nonsmoking women : results from a multicenter study in Eastern and Central Europe
- Author
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Davis, Ann, Tao, Meng-Hua, Chen, Jia, Scelo, Ghislaine, Bencko, Vladimir, Fabianova, Eleonora, Foretova, Lenka, Janout, Vladimir, Lissowska, Jolanta, Mates, Dana, Mates, Ioan N., Rudnai, Peter, Zaridze, David, and Boffetta, Paolo
- Published
- 2018
13. Sex specific associations in genome wide association analysis of renal cell carcinoma
- Author
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Laskar, Ruhina S., Muller, David C., Li, Peng, Machiela, Mitchell J., Ye, Yuanqing, Gaborieau, Valerie, Foll, Matthieu, Hofmann, Jonathan N., Colli, Leandro, Sampson, Joshua N., Wang, Zhaoming, Bacq-Daian, Delphine, Boland, Anne, Abedi-Ardekani, Behnoush, Durand, Geoffroy, Le Calvez-Kelm, Florence, Robinot, Nivonirina, Blanche, Helene, Prokhortchouk, Egor, Skryabin, Konstantin G., Burdett, Laurie, Yeager, Meredith, Radojevic-Skodric, Sanja, Savic, Slavisa, Foretova, Lenka, Holcatova, Ivana, Janout, Vladimir, Mates, Dana, Rascu, Stefan, Mukeria, Anush, Zaridze, David, Bencko, Vladimir, Cybulski, Cezary, Fabianova, Eleonora, Jinga, Viorel, Lissowska, Jolanta, Lubinski, Jan, Navratilova, Marie, Rudnai, Peter, Świątkowska, Beata, Benhamou, Simone, Cancel-Tassin, Geraldine, Cussenot, Olivier, Trichopoulou, Antonia, Riboli, Elio, Overvad, Kim, Panico, Salvatore, Ljungberg, Borje, Sitaram, Raviprakash T., Giles, Graham G., Milne, Roger L, Severi, Gianluca, Bruinsma, Fiona, Fletcher, Tony, Koppova, Kvetoslava, Larsson, Susanna C., Wolk, Alicja, Banks, Rosamonde E., Selby, Peter J., Easton, Douglas F., Pharoah, Paul, Andreotti, Gabriella, Beane Freeman, Laura E, Koutros, Stella, Albanes, Demetrius, Männistö, Satu, Weinstein, Stephanie, Clark, Peter E., Edwards, Todd L., Lipworth, Loren, Carol, Hallie, Freedman, Matthew L., Pomerantz, Mark M., Cho, Eunyoung, Kraft, Peter, Preston, Mark A., Wilson, Kathryn M., Michael Gaziano, J., Sesso, Howard D., Black, Amanda, Freedman, Neal D., Huang, Wen-Yi, Anema, John G., Kahnoski, Richard J., Lane, Brian R., Noyes, Sabrina L., Petillo, David, Teh, Bin Tean, Peters, Ulrike, White, Emily, Anderson, Garnet L., Johnson, Lisa, Luo, Juhua, Chow, Wong-Ho, Moore, Lee E., Choueiri, Toni K., Wood, Christopher, Johansson, Mattias, McKay, James D., Brown, Kevin M., Rothman, Nathaniel, Lathrop, Mark G., Deleuze, Jean-Francois, Wu, Xifeng, Brennan, Paul, Chanock, Stephen J., Purdue, Mark P., and Scelo, Ghislaine
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- 2019
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14. Metabolism of Low-Dose Inorganic Arsenic in a Central European Population: Influence of Sex and Genetic Polymorphisms
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Kumar, Rajiv, Rudnai, Peter, Fletcher, Tony, and Vahter, Marie
- Published
- 2007
15. Previous Lung Diseases and Lung Cancer Risk: A Pooled Analysis From the International Lung Cancer Consortium
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Brenner, Darren R, Boffetta, Paolo, Duell, Eric J, Bickeböller, Heike, Rosenberger, Albert, McCormack, Valerie, Muscat, Joshua E, Yang, Ping, Wichmann, H-Erich, Brueske-Hohlfeld, Irene, Schwartz, Ann G, Cote, Michele L, Tjønneland, Anne, Friis, Søren, Le Marchand, Loic, Zhang, Zuo-Feng, Morgenstern, Hal, Szeszenia-Dabrowska, Neonila, Lissowska, Jolanta, Zaridze, David, Rudnai, Peter, Fabianova, Eleonora, Foretova, Lenka, Janout, Vladimir, Bencko, Vladimir, Schejbalova, Miriam, Brennan, Paul, Mates, Ioan N, Lazarus, Philip, Field, John K, Raji, Olaide, McLaughlin, John R, Liu, Geoffrey, Wiencke, John, Neri, Monica, Ugolini, Donatella, Andrew, Angeline S, Lan, Qing, Hu, Wei, Orlow, Irene, Park, Bernard J, and Hung, Rayjean J
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Epidemiology ,Health Services and Systems ,Health Sciences ,Chronic Obstructive Pulmonary Disease ,Pneumonia ,Prevention ,Lung ,Tobacco Smoke and Health ,Cancer ,Tobacco ,Rare Diseases ,Pneumonia & Influenza ,Lung Cancer ,Infectious Diseases ,Respiratory ,Good Health and Well Being ,Bronchitis ,Chronic ,Humans ,Logistic Models ,Lung Neoplasms ,Proportional Hazards Models ,Pulmonary Emphysema ,Risk ,Risk Factors ,Self Report ,Tuberculosis ,Pulmonary ,bronchitis ,chronic ,emphysema ,lung diseases ,lung neoplasms ,meta-analysis ,pneumonia ,pulmonary disease ,chronic obstructive ,tuberculosis ,Mathematical Sciences ,Medical and Health Sciences - Abstract
To clarify the role of previous lung diseases (chronic bronchitis, emphysema, pneumonia, and tuberculosis) in the development of lung cancer, the authors conducted a pooled analysis of studies in the International Lung Cancer Consortium. Seventeen studies including 24,607 cases and 81,829 controls (noncases), mainly conducted in Europe and North America, were included (1984-2011). Using self-reported data on previous diagnoses of lung diseases, the authors derived study-specific effect estimates by means of logistic regression models or Cox proportional hazards models adjusted for age, sex, and cumulative tobacco smoking. Estimates were pooled using random-effects models. Analyses stratified by smoking status and histology were also conducted. A history of emphysema conferred a 2.44-fold increased risk of lung cancer (95% confidence interval (CI): 1.64, 3.62 (16 studies)). A history of chronic bronchitis conferred a relative risk of 1.47 (95% CI: 1.29, 1.68 (13 studies)). Tuberculosis (relative risk = 1.48, 95% CI: 1.17, 1.87 (16 studies)) and pneumonia (relative risk = 1.57, 95% CI: 1.22, 2.01 (12 studies)) were also associated with lung cancer risk. Among never smokers, elevated risks were observed for emphysema, pneumonia, and tuberculosis. These results suggest that previous lung diseases influence lung cancer risk independently of tobacco use and that these diseases are important for assessing individual risk.
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- 2012
16. Diet and the risk of head and neck cancer: a pooled analysis in the INHANCE consortium
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Chuang, Shu-Chun, Jenab, Mazda, Heck, Julia E, Bosetti, Cristina, Talamini, Renato, Matsuo, Keitaro, Castellsague, Xavier, Franceschi, Silvia, Herrero, Rolando, Winn, Deborah M, Vecchia, Carlo La, Morgenstern, Hal, Zhang, Zuo-Feng, Levi, Fabio, Maso, Luigino Dal, Kelsey, Karl, McClean, Michael D, Vaughan, Thomas, Lazarus, Philip, Muscat, Joshua, Ramroth, Heribert, Chen, Chu, Schwartz, Stephen M, Eluf-Neto, Jose, Hayes, Richard B, Purdue, Mark, Boccia, Stefania, Cadoni, Gabriella, Zaridze, David, Koifman, Sergio, Curado, Maria Paula, Ahrens, Wolfgang, Benhamou, Simone, Matos, Elena, Lagiou, Pagona, Szeszenia-Dabrowska, Neonilla, Olshan, Andrew F, Fernandez, Leticia, Menezes, Ana, Agudo, Antonio, Daudt, Alexander W, Merletti, Franco, Macfarlane, Gary J, Kjaerheim, Kristina, Mates, Dana, Holcatova, Ivana, Schantz, Stimson, Yu, Guo-Pei, Simonato, Lorenzo, Brenner, Hermann, Mueller, Heiko, Conway, David I, Thomson, Peter, Fabianova, Eleonora, Znaor, Ariana, Rudnai, Peter, Healy, Claire M, Ferro, Gilles, Brennan, Paul, Boffetta, Paolo, and Hashibe, Mia
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Nutrition ,Cancer ,Prevention ,Clinical Research ,Dental/Oral and Craniofacial Disease ,Adult ,Aged ,Case-Control Studies ,Diet ,Female ,Head and Neck Neoplasms ,Humans ,Male ,Middle Aged ,Risk Factors ,Head and neck cancer ,Fruit and vegetable ,Red meat ,Processed meat ,Oncology and Carcinogenesis ,Public Health and Health Services ,Epidemiology - Abstract
We investigated the association between diet and head and neck cancer (HNC) risk using data from the International Head and Neck Cancer Epidemiology (INHANCE) consortium. The INHANCE pooled data included 22 case-control studies with 14,520 cases and 22,737 controls. Center-specific quartiles among the controls were used for food groups, and frequencies per week were used for single food items. A dietary pattern score combining high fruit and vegetable intake and low red meat intake was created. Odds ratios (OR) and 95% confidence intervals (CI) for the dietary items on the risk of HNC were estimated with a two-stage random-effects logistic regression model. An inverse association was observed for higher-frequency intake of fruit (4th vs. 1st quartile OR = 0.52, 95% CI = 0.43-0.62, p (trend) < 0.01) and vegetables (OR = 0.66, 95% CI = 0.49-0.90, p (trend) = 0.01). Intake of red meat (OR = 1.40, 95% CI = 1.13-1.74, p (trend) = 0.13) and processed meat (OR = 1.37, 95% CI = 1.14-1.65, p (trend) < 0.01) was positively associated with HNC risk. Higher dietary pattern scores, reflecting high fruit/vegetable and low red meat intake, were associated with reduced HNC risk (per score increment OR = 0.90, 95% CI = 0.84-0.97).
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- 2012
17. In-Home Coal and Wood Use and Lung Cancer Risk: A Pooled Analysis of the International Lung Cancer Consortium
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Hosgood, H Dean, Boffetta, Paolo, Greenland, Sander, Lee, Yuan-Chin Amy, McLaughlin, John, Seow, Adeline, Duell, Eric J, Andrew, Angeline S, Zaridze, David, Szeszenia-Dabrowska, Neonila, Rudnai, Peter, Lissowska, Jolanta, Fabiánová, Eleonóra, Mates, Dana, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Morgenstern, Hal, Rothman, Nathaniel, Hung, Rayjean J, Brennan, Paul, and Lan, Qing
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Health Services and Systems ,Biomedical and Clinical Sciences ,Health Sciences ,Oncology and Carcinogenesis ,Lung ,Clinical Research ,Cancer ,Prevention ,Lung Cancer ,Respiratory ,Aged ,Air Pollution ,Indoor ,Coal ,Cooking ,Female ,Heating ,Humans ,International Agencies ,Lung Neoplasms ,Male ,Middle Aged ,Risk Factors ,Wood ,coal ,lung cancer ,pooled ,risk factor ,wood ,Environmental Sciences ,Medical and Health Sciences ,Toxicology ,Biomedical and clinical sciences ,Environmental sciences ,Health sciences - Abstract
BackgroundDomestic fuel combustion from cooking and heating is an important public health issue because roughly 3 billion people are exposed worldwide. Recently, the International Agency for Research on Cancer classified indoor emissions from household coal combustion as a human carcinogen (group 1) and from biomass fuel (primarily wood) as a probable human carcinogen (group 2A).ObjectivesWe pooled seven studies from the International Lung Cancer Consortium (5,105 cases and 6,535 controls) to provide further epidemiological evaluation of the association between in-home solid-fuel use, particularly wood, and lung cancer risk.MethodsUsing questionnaire data, we classified subjects as predominant solid-fuel users (e.g., coal, wood) or nonsolid-fuel users (e.g., oil, gas, electricity). Unconditional logistic regression was used to estimate the odds ratios (ORs) and to compute 95% confidence intervals (CIs), adjusting for age, sex, education, smoking status, race/ethnicity, and study center.ResultsCompared with nonsolid-fuel users, predominant coal users (OR = 1.64; 95% CI, 1.49-1.81), particularly coal users in Asia (OR = 4.93; 95% CI, 3.73-6.52), and predominant wood users in North American and European countries (OR = 1.21; 95% CI, 1.06-1.38) experienced higher risk of lung cancer. The results were similar in never-smoking women and other subgroups.ConclusionsOur results are consistent with previous observations pertaining to in-home coal use and lung cancer risk, support the hypothesis of a carcinogenic potential of in-home wood use, and point to the need for more detailed study of factors affecting these associations.
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- 2010
18. Occupational Exposure to Vinyl Chloride, Acrylonitrile and Styrene and Lung Cancer Risk (Europe)
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Scélo, Ghislaine, Constantinescu, Vali, Csiki, Irma, Zaridze, David, Szeszenia-Dabrowska, Neonila, Rudnai, Peter, Lissowska, Jolanta, Fabiánová, Eleonóra, Cassidy, Adrian, Slamova, Alena, Foretova, Lenka, Janout, Vladimir, Fevotte, Joelle, Fletcher, Tony, Brennan, Paul, and Boffetta, Paolo
- Published
- 2004
19. Exposure–Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case–Control Studies
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Olsson, Ann C., Vermeulen, Roel, Schüz, Joachim, Kromhout, Hans, Pesch, Beate, Peters, Susan, Behrens, Thomas, Portengen, Lützen, Mirabelli, Dario, Gustavsson, Per, Kendzia, Benjamin, Almansa, Josue, Luzon, Veronique, Vlaanderen, Jelle, Stücker, Isabelle, Guida, Florence, Consonni, Dario, Caporaso, Neil, Landi, Maria Teresa, Field, John, Brüske, Irene, Wichmann, Heinz-Erich, Siemiatycki, Jack, Parent, Marie-Elise, Richiardi, Lorenzo, Merletti, Franco, Jöckel, Karl-Heinz, Ahrens, Wolfgang, Pohlabeln, Hermann, Plato, Nils, Tardón, Adonina, Zaridze, David, McLaughlin, John, Demers, Paul, Szeszenia-Dabrowska, Neonila, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Dumitru, Rodica Stanescu, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Boffetta, Paolo, Bueno-de-Mesquita, Bas, Forastiere, Francesco, Brüning, Thomas, and Straif, Kurt
- Published
- 2017
20. Diet and the risk of head and neck cancer: A pooled analysis in the INHANCE consortium
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Chuang, Shu-Chun, Jenab, Mazda, Heck, Julia, Olshan, Andrew, Bencko, Vladimir, Schantz, Stimson, Paula Curado, Maria, Mates, Dana, McClean, Michael, Daudt, Alexander, Franceschi, Silvia, Zaridze, David, Koifman, Sergio, Lazarus, Philip, Herrero, Rolando, Fabianova, Eleonora, Maso Luigino, Dal, Zhang, Zuo-Feng, Muscat, Joshua, Talamini, Renato, Rudnai, Peter, Fernandez, Leticia, Lissowska, Jola, Menezes, Ana, Levi, Fabio, Hayes, Richard, Benhamou, Simone, Eluf-Neto, Jose, Boccia, Stefania, and Matos, Elena
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Oncology & Carcinogenesis ,Oncology and Carcinogenesis - Published
- 2009
21. Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma
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Machiela, Mitchell J., Hofmann, Jonathan N., Carreras-Torres, Robert, Brown, Kevin M., Johansson, Mattias, Wang, Zhaoming, Foll, Matthieu, Li, Peng, Rothman, Nathaniel, Savage, Sharon A., Gaborieau, Valerie, McKay, James D., Ye, Yuanqing, Henrion, Marc, Bruinsma, Fiona, Jordan, Susan, Severi, Gianluca, Hveem, Kristian, Vatten, Lars J., Fletcher, Tony, Koppova, Kvetoslava, Larsson, Susanna C., Wolk, Alicja, Banks, Rosamonde E., Selby, Peter J., Easton, Douglas F., Pharoah, Paul, Andreotti, Gabriella, Freeman, Laura E. Beane, Koutros, Stella, Albanes, Demetrius, Mannisto, Satu, Weinstein, Stephanie, Clark, Peter E., Edwards, Todd E., Lipworth, Loren, Gapstur, Susan M., Stevens, Victoria L., Carol, Hallie, Freedman, Matthew L., Pomerantz, Mark M., Cho, Eunyoung, Kraft, Peter, Preston, Mark A., Wilson, Kathryn M., Gaziano, J. Michael, Sesso, Howard S., Black, Amanda, Freedman, Neal D., Huang, Wen-Yi, Anema, John G., Kahnoski, Richard J., Lane, Brian R., Noyes, Sabrina L., Petillo, David, Colli, Leandro M., Sampson, Joshua N., Besse, Celine, Blanche, Helene, Boland, Anne, Burdette, Laurie, Prokhortchouk, Egor, Skryabin, Konstantin G., Yeager, Meredith, Mijuskovic, Mirjana, Ognjanovic, Miodrag, Foretova, Lenka, Holcatova, Ivana, Janout, Vladimir, Mates, Dana, Mukeriya, Anush, Rascu, Stefan, Zaridze, David, Bencko, Vladimir, Cybulski, Cezary, Fabianova, Eleonora, Jinga, Viorel, Lissowska, Jolanta, Lubinski, Jan, Navratilova, Marie, Rudnai, Peter, Szeszenia-Dabrowska, Neonila, Benhamou, Simone, Cancel-Tassin, Geraldine, Cussenot, Olivier, Bueno-de-Mesquita, H. Bas, Canzian, Federico, Duell, Eric J., Ljungberg, Börje, Sitaram, Raviprakash T., Peters, Ulrike, White, Emily, Anderson, Garnet L., Johnson, Lisa, Luo, Juhua, Buring, Julie, Lee, I-Min, Chow, Wong-Ho, Moore, Lee E., Wood, Christopher, Eisen, Timothy, Larkin, James, Choueiri, Toni K., Lathrop, G. Mark, Teh, Bin Tean, Deleuze, Jean-Francois, Wu, Xifeng, Houlston, Richard S., Brennan, Paul, Chanock, Stephen J., Scelo, Ghislaine, and Purdue, Mark P.
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- 2017
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22. Newborns health in the Danube Region: Environment, biomonitoring, interventions and economic benefits in a large prospective birth cohort study
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Andersen, Zorana J., Sram, Radim J., Ščasný, Milan, Gurzau, Eugen S., Fucic, Aleksandra, Gribaldo, Laura, Rossner, Pavel, Jr, Rossnerova, Andrea, Kohlová, Markéta Braun, Máca, Vojtěch, Zvěřinová, Iva, Gajdosova, Dagmar, Moshammer, Hanns, Rudnai, Peter, and Knudsen, Lisbeth E.
- Published
- 2016
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23. Lung Cancer Among Firefighters : Smoking-Adjusted Risk Estimates in a Pooled Analysis of Case-Control Studies
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Bigert, Carolina, Gustavsson, Per, Straif, Kurt, Taeger, Dirk, Pesch, Beate, Kendzia, Benjamin, Schüz, Joachim, Stücker, Isabelle, Guida, Florence, Brüske, Irene, Wichmann, Heinz-Erich, Pesatori, Angela C., Landi, Maria Teresa, Caporaso, Neil, Tse, Lap Ah, Yu, Ignatius Tak-sun, Siemiatycki, Jack, Lavoué, Jérôme, Richiardi, Lorenzo, Mirabelli, Dario, Simonato, Lorenzo, Jöckel, Karl-Heinz, Ahrens, Wolfgang, Pohlabeln, Hermann, Tardón, Adonina, Zaridze, David, Field, John K., Mannetje, Andrea ’t, Pearce, Neil, McLaughlin, John, Demers, Paul, Szeszenia-Dabrowska, Neonila, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Dumitru, Rodica Stanescu, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Boffetta, Paolo, Peters, Susan, Vermeulen, Roel, Kromhout, Hans, Brüning, Thomas, and Olsson, Ann C.
- Published
- 2016
24. Supplementary Tables S1-S6 from Effect of Occupational Exposures on Lung Cancer Susceptibility: A Study of Gene–Environment Interaction Analysis
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Malhotra, Jyoti, primary, Sartori, Samantha, primary, Brennan, Paul, primary, Zaridze, David, primary, Szeszenia-Dabrowska, Neonila, primary, Świątkowska, Beata, primary, Rudnai, Peter, primary, Lissowska, Jolanta, primary, Fabianova, Eleonora, primary, Mates, Dana, primary, Bencko, Vladimir, primary, Gaborieau, Valerie, primary, Stücker, Isabelle, primary, Foretova, Lenka, primary, Janout, Vladimir, primary, and Boffetta, Paolo, primary
- Published
- 2023
- Full Text
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25. Data from No Causal Association Identified for Human Papillomavirus Infections in Lung Cancer
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Anantharaman, Devasena, primary, Gheit, Tarik, primary, Waterboer, Tim, primary, Halec, Gordana, primary, Carreira, Christine, primary, Abedi-Ardekani, Behnoush, primary, McKay-Chopin, Sandrine, primary, Zaridze, David, primary, Mukeria, Anush, primary, Szeszenia-Dabrowska, Neonila, primary, Lissowska, Jolanta, primary, Mates, Dana, primary, Janout, Vladimir, primary, Foretova, Lenka, primary, Bencko, Vladimir, primary, Rudnai, Peter, primary, Fabianova, Eleonora, primary, Tjønneland, Anne, primary, Travis, Ruth C., primary, Boeing, Heiner, primary, Quirós, J. Ramón, primary, Johansson, Mikael, primary, Krogh, Vittorio, primary, Bueno-de-Mesquita, H. Bas, primary, Kotanidou, Anastasia, primary, Clavel-Chapelon, Françoise, primary, Weiderpass, Elisabete, primary, Johansson, Mattias, primary, Pawlita, Michael, primary, Scelo, Ghislaine, primary, Tommasino, Massimo, primary, and Brennan, Paul, primary
- Published
- 2023
- Full Text
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26. Supplementary Table 3 from No Causal Association Identified for Human Papillomavirus Infections in Lung Cancer
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Anantharaman, Devasena, primary, Gheit, Tarik, primary, Waterboer, Tim, primary, Halec, Gordana, primary, Carreira, Christine, primary, Abedi-Ardekani, Behnoush, primary, McKay-Chopin, Sandrine, primary, Zaridze, David, primary, Mukeria, Anush, primary, Szeszenia-Dabrowska, Neonila, primary, Lissowska, Jolanta, primary, Mates, Dana, primary, Janout, Vladimir, primary, Foretova, Lenka, primary, Bencko, Vladimir, primary, Rudnai, Peter, primary, Fabianova, Eleonora, primary, Tjønneland, Anne, primary, Travis, Ruth C., primary, Boeing, Heiner, primary, Quirós, J. Ramón, primary, Johansson, Mikael, primary, Krogh, Vittorio, primary, Bueno-de-Mesquita, H. Bas, primary, Kotanidou, Anastasia, primary, Clavel-Chapelon, Françoise, primary, Weiderpass, Elisabete, primary, Johansson, Mattias, primary, Pawlita, Michael, primary, Scelo, Ghislaine, primary, Tommasino, Massimo, primary, and Brennan, Paul, primary
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- 2023
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27. Supplementary Figure Legend from Polymorphisms in DNA Repair Genes, Smoking, and Bladder Cancer Risk: Findings from the International Consortium of Bladder Cancer
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Stern, Mariana C., primary, Lin, Jie, primary, Figueroa, Jonine D., primary, Kelsey, Karl T., primary, Kiltie, Anne E., primary, Yuan, Jian-Min, primary, Matullo, Giuseppe, primary, Fletcher, Tony, primary, Benhamou, Simone, primary, Taylor, Jack A., primary, Placidi, Donatella, primary, Zhang, Zuo-Feng, primary, Steineck, Gunnar, primary, Rothman, Nathaniel, primary, Kogevinas, Manolis, primary, Silverman, Debra, primary, Malats, Nuria, primary, Chanock, Stephen, primary, Wu, Xifeng, primary, Karagas, Margaret R., primary, Andrew, Angeline S., primary, Nelson, Heather H., primary, Bishop, D. Timothy, primary, Sak, Sei Chung, primary, Choudhury, Ananya, primary, Barrett, Jennifer H., primary, Elliot, Faye, primary, Corral, Román, primary, Joshi, Amit D., primary, Gago-Dominguez, Manuela, primary, Cortessis, Victoria K., primary, Xiang, Yong-Bing, primary, Gao, Yu-Tang, primary, Vineis, Paolo, primary, Sacerdote, Carlotta, primary, Guarrera, Simonetta, primary, Polidoro, Silvia, primary, Allione, Alessandra, primary, Gurzau, Eugen, primary, Koppova, Kvetoslava, primary, Kumar, Rajiv, primary, Rudnai, Peter, primary, Porru, Stefano, primary, Carta, Angela, primary, Campagna, Marcello, primary, Arici, Cecilia, primary, Park, Sung Shim Lani, primary, and Garcia-Closas, Montserrat, primary
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- 2023
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28. Supplementary Table 2 from No Causal Association Identified for Human Papillomavirus Infections in Lung Cancer
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Anantharaman, Devasena, primary, Gheit, Tarik, primary, Waterboer, Tim, primary, Halec, Gordana, primary, Carreira, Christine, primary, Abedi-Ardekani, Behnoush, primary, McKay-Chopin, Sandrine, primary, Zaridze, David, primary, Mukeria, Anush, primary, Szeszenia-Dabrowska, Neonila, primary, Lissowska, Jolanta, primary, Mates, Dana, primary, Janout, Vladimir, primary, Foretova, Lenka, primary, Bencko, Vladimir, primary, Rudnai, Peter, primary, Fabianova, Eleonora, primary, Tjønneland, Anne, primary, Travis, Ruth C., primary, Boeing, Heiner, primary, Quirós, J. Ramón, primary, Johansson, Mikael, primary, Krogh, Vittorio, primary, Bueno-de-Mesquita, H. Bas, primary, Kotanidou, Anastasia, primary, Clavel-Chapelon, Françoise, primary, Weiderpass, Elisabete, primary, Johansson, Mattias, primary, Pawlita, Michael, primary, Scelo, Ghislaine, primary, Tommasino, Massimo, primary, and Brennan, Paul, primary
- Published
- 2023
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29. Supplementary Tables 1-8 from Polymorphisms in DNA Repair Genes, Smoking, and Bladder Cancer Risk: Findings from the International Consortium of Bladder Cancer
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Stern, Mariana C., primary, Lin, Jie, primary, Figueroa, Jonine D., primary, Kelsey, Karl T., primary, Kiltie, Anne E., primary, Yuan, Jian-Min, primary, Matullo, Giuseppe, primary, Fletcher, Tony, primary, Benhamou, Simone, primary, Taylor, Jack A., primary, Placidi, Donatella, primary, Zhang, Zuo-Feng, primary, Steineck, Gunnar, primary, Rothman, Nathaniel, primary, Kogevinas, Manolis, primary, Silverman, Debra, primary, Malats, Nuria, primary, Chanock, Stephen, primary, Wu, Xifeng, primary, Karagas, Margaret R., primary, Andrew, Angeline S., primary, Nelson, Heather H., primary, Bishop, D. Timothy, primary, Sak, Sei Chung, primary, Choudhury, Ananya, primary, Barrett, Jennifer H., primary, Elliot, Faye, primary, Corral, Román, primary, Joshi, Amit D., primary, Gago-Dominguez, Manuela, primary, Cortessis, Victoria K., primary, Xiang, Yong-Bing, primary, Gao, Yu-Tang, primary, Vineis, Paolo, primary, Sacerdote, Carlotta, primary, Guarrera, Simonetta, primary, Polidoro, Silvia, primary, Allione, Alessandra, primary, Gurzau, Eugen, primary, Koppova, Kvetoslava, primary, Kumar, Rajiv, primary, Rudnai, Peter, primary, Porru, Stefano, primary, Carta, Angela, primary, Campagna, Marcello, primary, Arici, Cecilia, primary, Park, Sung Shim Lani, primary, and Garcia-Closas, Montserrat, primary
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- 2023
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30. Supplementary Table 1 from No Causal Association Identified for Human Papillomavirus Infections in Lung Cancer
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Anantharaman, Devasena, primary, Gheit, Tarik, primary, Waterboer, Tim, primary, Halec, Gordana, primary, Carreira, Christine, primary, Abedi-Ardekani, Behnoush, primary, McKay-Chopin, Sandrine, primary, Zaridze, David, primary, Mukeria, Anush, primary, Szeszenia-Dabrowska, Neonila, primary, Lissowska, Jolanta, primary, Mates, Dana, primary, Janout, Vladimir, primary, Foretova, Lenka, primary, Bencko, Vladimir, primary, Rudnai, Peter, primary, Fabianova, Eleonora, primary, Tjønneland, Anne, primary, Travis, Ruth C., primary, Boeing, Heiner, primary, Quirós, J. Ramón, primary, Johansson, Mikael, primary, Krogh, Vittorio, primary, Bueno-de-Mesquita, H. Bas, primary, Kotanidou, Anastasia, primary, Clavel-Chapelon, Françoise, primary, Weiderpass, Elisabete, primary, Johansson, Mattias, primary, Pawlita, Michael, primary, Scelo, Ghislaine, primary, Tommasino, Massimo, primary, and Brennan, Paul, primary
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- 2023
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31. Supplementary Figure 1 from Polymorphisms in DNA Repair Genes, Smoking, and Bladder Cancer Risk: Findings from the International Consortium of Bladder Cancer
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Stern, Mariana C., primary, Lin, Jie, primary, Figueroa, Jonine D., primary, Kelsey, Karl T., primary, Kiltie, Anne E., primary, Yuan, Jian-Min, primary, Matullo, Giuseppe, primary, Fletcher, Tony, primary, Benhamou, Simone, primary, Taylor, Jack A., primary, Placidi, Donatella, primary, Zhang, Zuo-Feng, primary, Steineck, Gunnar, primary, Rothman, Nathaniel, primary, Kogevinas, Manolis, primary, Silverman, Debra, primary, Malats, Nuria, primary, Chanock, Stephen, primary, Wu, Xifeng, primary, Karagas, Margaret R., primary, Andrew, Angeline S., primary, Nelson, Heather H., primary, Bishop, D. Timothy, primary, Sak, Sei Chung, primary, Choudhury, Ananya, primary, Barrett, Jennifer H., primary, Elliot, Faye, primary, Corral, Román, primary, Joshi, Amit D., primary, Gago-Dominguez, Manuela, primary, Cortessis, Victoria K., primary, Xiang, Yong-Bing, primary, Gao, Yu-Tang, primary, Vineis, Paolo, primary, Sacerdote, Carlotta, primary, Guarrera, Simonetta, primary, Polidoro, Silvia, primary, Allione, Alessandra, primary, Gurzau, Eugen, primary, Koppova, Kvetoslava, primary, Kumar, Rajiv, primary, Rudnai, Peter, primary, Porru, Stefano, primary, Carta, Angela, primary, Campagna, Marcello, primary, Arici, Cecilia, primary, Park, Sung Shim Lani, primary, and Garcia-Closas, Montserrat, primary
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- 2023
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32. Communication in a Human biomonitoring study: Focus group work, public engagement and lessons learnt in 17 European countries
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Exley, Karen, Cano, Noemi, Aerts, Dominique, Biot, Pierre, Casteleyn, Ludwine, Kolossa-Gehring, Marike, Schwedler, Gerda, Castaño, Argelia, Angerer, Jürgen, Koch, Holger M., Esteban, Marta, Schoeters, Greet, Den Hond, Elly, Horvat, Milena, Bloemen, Louis, Knudsen, Lisbeth E., Joas, Reinhard, Joas, Anke, Dewolf, Marie-Christine, Van de Mieroop, Els, Katsonouri, Andromachi, Hadjipanayis, Adamos, Cerna, Milena, Krskova, Andrea, Becker, Kerstin, Fiddicke, Ulrike, Seiwert, Margarete, Mørck, Thit A., Rudnai, Peter, Kozepesy, Szilvia, Cullen, Elizabeth, Kellegher, Anne, Gutleb, Arno C., Fischer, Marc E., Ligocka, Danuta, Kamińska, Joanna, Namorado, Sónia, Fátima Reis, M., Lupsa, Ioana-Rodica, Gurzau, Anca E., Halzlova, Katarina, Jajcaj, Michal, Mazej, Darja, Tratnik, Janja Snoj, Huetos, Olga, López, Ana, Berglund, Marika, Larsson, Kristin, and Sepai, Ovnair
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- 2015
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33. Fish consumption patterns and hair mercury levels in children and their mothers in 17 EU countries
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Castaño, Argelia, Cutanda, Francisco, Esteban, Marta, Pärt, Peter, Navarro, Carmen, Gómez, Silvia, Rosado, Montserrat, López, Ana, López, Estrella, Exley, Karen, Schindler, Birgit K., Govarts, Eva, Casteleyn, Ludwine, Kolossa-Gehring, Marike, Fiddicke, Ulrike, Koch, Holger, Angerer, Jürgen, Hond, Elly Den, Schoeters, Greet, Sepai, Ovnair, Horvat, Milena, Knudsen, Lisbeth E., Aerts, Dominique, Joas, Anke, Biot, Pierre, Joas, Reinhard, Jiménez-Guerrero, José A., Diaz, Gema, Pirard, Catherine, Katsonouri, Andromachi, Cerna, Milena, Gutleb, Arno C., Ligocka, Danuta, Reis, Fátima M, Berglund, Marika, Lupsa, Ioana-Rodica, Halzlová, Katarína, Charlier, Corinne, Cullen, Elizabeth, Hadjipanayis, Adamos, Krsková, Andrea, Jensen, Janne F, Nielsen, Jeanette K, Schwedler, Gerda, Wilhelm, Michael, Rudnai, Peter, Középesy, Szilvia, Davidson, Fred, Fischer, Mark E., Janasik, Beata, Namorado, Sónia, Gurzau, Anca E., Jajcaj, Michal, Mazej, Darja, Tratnik, Janja Snoj, Larsson, Kristin, Lehmann, Andrea, Crettaz, Pierre, Lavranos, Giagkos, and Posada, Manuel
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- 2015
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34. Policy recommendations and cost implications for a more sustainable framework for European human biomonitoring surveys
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Joas, Anke, Knudsen, Lisbeth E., Kolossa-Gehring, Marike, Sepai, Ovnair, Casteleyn, Ludwine, Schoeters, Greet, Angerer, Jürgen, Castaño, Argelia, Aerts, Dominique, Biot, Pierre, Horvat, Milena, Bloemen, Louis, Reis, M. Fátima, Lupsa, Ioana-Rodica, Katsonouri, Andromachi, Cerna, Milena, Berglund, Marika, Crettaz, Pierre, Rudnai, Peter, Halzlova, Katarina, Mulcahy, Maurice, Gutleb, Arno C., Fischer, Marc E., Becher, Georg, Fréry, Nadine, Jensen, Genon, Van Vliet, Lisette, Koch, Holger M., Hond, Elly Den, Fiddicke, Ulrike, Esteban, Marta, Exley, Karen, Schwedler, Gerda, Seiwert, Margarete, Ligocka, Danuta, Hohenblum, Philipp, Kyrtopoulos, Soterios, Botsivali, Maria, DeFelip, Elena, Guillou, Claude, Reniero, Fabiano, Grazuleviciene, Regina, Veidebaum, Toomas, Mørck, Thit A., Nielsen, Jeanette K.S., Jensen, Janne F., Rivas, Teresa C., Sanchez, Jinny, Koppen, Gudrun, Smolders, Roel, Kozepesy, Szilvia, Hadjipanayis, Adamos, Krskova, Andrea, Mannion, Rory, Jakubowski, Marek, Fucic, J. Aleksandra, Pereira-Miguel, Jose, Gurzau, Anca E., Jajcaj, Michal, Mazej, Darja, Tratnik, Janja Snoj, Lehmann, Andrea, Larsson, Kristin, Dumez, Birgit, and Joas, Reinhard
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- 2015
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35. Exposure determinants of cadmium in European mothers and their children
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Berglund, Marika, Larsson, Kristin, Grandér, Margaretha, Casteleyn, Ludwine, Kolossa-Gehring, Marike, Schwedler, Gerda, Castaño, Argelia, Esteban, Marta, Angerer, Jürgen, Koch, Holger M., Schindler, Birgit K., Schoeters, Greet, Smolders, Roel, Exley, Karen, Sepai, Ovnair, Blumen, Luies, Horvat, Milena, Knudsen, Lisbeth E., Mørck, Thit A., Joas, Anke, Joas, Reinhard, Biot, Pierre, Aerts, Dominique, De Cremer, Koen, Van Overmeire, Ilse, Katsonouri, Andromachi, Hadjipanayis, Adamos, Cerna, Milena, Krskova, Andrea, Nielsen, Jeanette K.S., Jensen, Janne Fangel, Rudnai, Peter, Kozepesy, Szilvia, Griffin, Chris, Nesbitt, Ian, Gutleb, Arno C., Fischer, Marc E., Ligocka, Danuta, Jakubowski, Marek, Reis, M. Fátima, Namorado, Sónia, Lupsa, Ioana-Rodica, Gurzau, Anca E., Halzlova, Katarina, Jajcaj, Michal, Mazej, Darja, Tratnik, Janja Snoj, Lopez, Ana, Cañas, Ana, Lehmann, Andrea, Crettaz, Pierre, Hond, Elly Den, and Govarts, Eva
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- 2015
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36. Lessons learnt on recruitment and fieldwork from a pilot European human biomonitoring survey
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Fiddicke, Ulrike, Becker, Kerstin, Schwedler, Gerda, Seiwert, Margarete, Joas, Reinhard, Joas, Anke, Biot, Pierre, Aerts, Dominique, Casteleyn, Ludwine, Dumez, Birgit, Castaño, Argelia, Esteban, Marta, Angerer, Jürgen, Koch, Holger M., Schoeters, Greet, Hond, Elly Den, Sepai, Ovnair, Exley, Karen, Knudsen, Lisbeth E., Horvat, Milena, Bloemen, Louis, Katsonouri, Andromachi, Hadjipanayis, Adamos, Cerna, Milena, Krsková, Andrea, Jensen, Janne Fangel, Nielsen, Jeanette K.S., Rudnai, Peter, Közepésy, Szilvia, Gutleb, Arno C., Fischer, Marc E., Ligocka, Danuta, Kamińska, Joanna, Reis, M. Fátima, Namorado, Sónia, Lupsa, Ioana-Rodica, Gurzau, Anca E., Halzlová, Katarína, Mazej, Darja, Tratnik, Janja Snoj, Rivas, Teresa C., Gómez, Silvia, Berglund, Marika, Larsson, Kristin, Lehmann, Andrea, Crettaz, Pierre, Dewolf, Marie-Christine, Burns, Damien, Kellegher, Anne, and Kolossa-Gehring, Marike
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- 2015
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37. Case study: Possible differences in phthalates exposure among the Czech, Hungarian, and Slovak populations identified based on the DEMOCOPHES pilot study results
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Černá, Milena, Malý, Marek, Rudnai, Peter, Középesy, Szilvia, Náray, Miklós, Halzlová, Katarina, Jajcaj, Michal, Grafnetterová, Anna, Krsková, Andrea, Antošová, Danuše, Forysová, Kateřina, Hond, Elly Den, Schoeters, Greet, Joas, Reinhard, Casteleyn, Ludwine, Joas, Anke, Biot, Pierre, Aerts, Dominique, Angerer, Jürgen, Bloemen, Louis, Castaño, Argelia, Esteban, Marta, Koch, Holger M., Kolossa-Gehring, Marike, Gutleb, Arno C., Pavloušková, Jana, and Vrbík, Karel
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- 2015
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38. From science to policy : how European HBM indicators help to answer related to and DINCH
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Gerofke, Antje, David, Madlen, Schmidt, Phillipp, Vicente, Joana Lobo, Buekers, Jurgen, Gilles, Liese, Colles, Ann, Bessems, Jos, Bastiaensen, Michiel, Covaci, Adrian, Den Hond, Elly, Koppen, Gudrun, Laeremans, Michelle, Verheyen, Veerle J., Cerna, Milena, Klanova, Jana, Krskova, Andrea, Zvonar, Martin, Knudsen, Lisbeth E., Koch, Holger M., Jensen, Tina Kold, Rambaud, Loic, Riou, Margaux, Vogel, Nina, Gabriel, Catherine, Karakitsios, Spyros, Papaioannou, Nafsika, Sarigiannis, Denis, Kakucs, Reka, Kozepesy, Szilvia, Rudnai, Peter, Szigeti, Tamas, Barbone, Fabio, Rosolen, Valentina, Guignard, Cedric, Gutleb, Arno C., Sakhi, Amrit Kaur, Haug, Line Smastuen, Janasik, Beata, Ligocka, Danuta, Estokova, Milada, Fabelova, Lucia, Kolena, Branislav, Murinova, Lubica Palkovicova, Petrovicova, Ida, Richterova, Denisa, Horvat, Milena, Mazej, Darja, Tratnik, Janja Snoj, Runkel, Agneta Annika, Castano, Argelia, Esteban-Lopez, Marta, Pedraza-Diaz, Susana, Akesson, Agneta, Lignell, Sanna, Vlaanderen, Jelle, Zock, Jan-Paul, Schoeters, Greet, and Kolossa-Gehring, Marike
- Subjects
Human medicine - Abstract
Within the European Human Biomonitoring (HBM) Initiative HBM4EU we derived HBM indicators that were designed to help answering key policy questions and support chemical policies. The result indicators convey information on chemicals exposure of different age groups, sexes, geographical regions and time points by comparing median exposure values. If differences are observed for one group or the other, policy measures or risk management options can be implemented. Impact indicators support health risk assessment by comparing exposure values with health-based guidance values, such as human biomonitoring guidance values (HBM-GVs). In general, the indicators should be designed to translate complex scientific information into short and clear messages and make it accessible to policy makers but also to a broader audience such as stakeholders (e.g. NGO's), other scientists and the general public. Based on harmonized data from the HBM4EU Aligned Studies (2014-2021), the usefulness of our indicators was demonstrated for the age group children (6-11 years), using two case examples: one phthalate (Diisobutyl phthalate: DiBP) and one non-phthalate substitute (Di-isononyl cyclohexane-1,2- dicarboxylate: DINCH). For the comparison of age groups, these were compared to data for teenagers (12-18 years), and time periods were compared using data from the DEMOCOPHES project (2011-2012). Our result indicators proved to be suitable for demonstrating the effectiveness of policy measures for DiBP and the need of continuous monitoring for DINCH. They showed similar exposure for boys and girls, indicating that there is no need for gender focused interventions and/or no indication of sex-specific exposure patterns. They created a basis for a targeted approach by highlighting relevant geographical differences in internal exposure. An adequate data basis is essential for revealing differences for all indicators. This was particularly evident in our studies on the indicators on age differences. The impact indicator revealed that health risks based on exposure to DiBP cannot be excluded. This is an indication or flag for risk managers and policy makers that exposure to DiBP still is a relevant health issue. HBM indicators derived within HBM4EU are a valuable and important complement to existing indicator lists in the context of environment and health. Their applicability, current shortcomings and solution strategies are outlined.
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- 2023
39. Lung cancer among coal miners, ore miners and quarrymen: smoking-adjusted risk estimates from the synergy pooled analysis of case–control studies
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Taeger, Dirk, Pesch, Beate, Kendzia, Benjamin, Behrens, Thomas, Jöckel, Karl-Heinz, Dahmann, Dirk, Siemiatycki, Jack, Kromhout, Hans, Vermeulen, Roel, Peters, Susan, Olsson, Ann, Brüske, Irene, Wichmann, Heinz-Erich, Stücker, Isabelle, Guida, Florence, Tardón, Adonina, Merletti, Franco, Mirabelli, Dario, Richiardi, Lorenzo, Pohlabeln, Hermann, Ahrens, Wolfgang, Landi, Maria Teresa, Caporaso, Neil, Pesatori, Angela Cecilia, Mukeriya, Anush, Szeszenia-Dabrowska, Neonila, Lissowska, Jolanta, Gustavsson, Per, Field, John, Marcus, Michael W, Fabianova, Eleonora, 't Mannetje, Andrea, Pearce, Neil, Rudnai, Peter, Bencko, Vladimir, Janout, Vladimir, Dumitru, Rodica Stanescu, Foretova, Lenka, Forastiere, Francesco, McLaughlin, John, Demers, Paul, Bueno-de-Mesquita, Bas, Schüz, Joachim, Straif, Kurt, and Brüning, Thomas
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- 2015
40. Lung Cancer Risk Among Cooks When Accounting for Tobacco Smoking : A Pooled Analysis of Case–Control Studies From Europe, Canada, New Zealand, and China
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Bigert, Carolina, Gustavsson, Per, Straif, Kurt, Pesch, Beate, Brüning, Thomas, Kendzia, Benjamin, Schüz, Joachim, Stücker, Isabelle, Guida, Florence, Brüske, Irene, Wichmann, Heinz-Erich, Pesatori, Angela C., Landi, Maria Teresa, Caporaso, Neil, Tse, Lap Ah, Yu, Ignatius Tak-sun, Siemiatycki, Jack, Pintos, Javier, Merletti, Franco, Mirabelli, Dario, Simonato, Lorenzo, Jöckel, Karl-Heinz, Ahrens, Wolfgang, Pohlabeln, Hermann, Tardón, Adonina, Zaridze, David, Field, John, ‘t Mannetje, Andrea, Pearce, Neil, McLaughlin, John, Demers, Paul, Szeszenia-Dabrowska, Neonila, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Dumitru, Rodica Stanescu, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Boffetta, Paolo, Forastiere, Francesco, Bueno-de-Mesquita, Bas, Peters, Susan, Vermeulen, Roel, Kromhout, Hans, and Olsson, Ann C.
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- 2015
41. Changing Children’s Blood Lead Level in Hungary 1986–2006
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Dura, Gyula, Pándics, Tamás, Rudnai, Péter, Simeonov, Lubomir I., editor, Kochubovski, Mihail V., editor, and Simeonova, Biana G., editor
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- 2011
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42. Arsenic in drinking water and congenital heart anomalies in Hungary
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Rudnai, Tamás, Sándor, János, Kádár, Mihály, Borsányi, Mátyás, Béres, Judit, Métneki, Júlia, Maráczi, Gabriella, and Rudnai, Péter
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- 2014
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43. Polymorphisms in DNA repair genes XRCC1 and XRCC3, occupational exposure to arsenic and sunlight, and the risk of non-melanoma skin cancer in a European case-control study
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Surdu, Simona, Fitzgerald, Edward F., Bloom, Michael S., Boscoe, Francis P., Carpenter, David O., Haase, Richard F., Gurzau, Eugen, Rudnai, Peter, Koppova, Kvetoslava, Vahter, Marie, Leonardi, Giovanni, Goessler, Walter, Kumar, Rajiv, and Fletcher, Tony
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- 2014
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44. The European COPHES/DEMOCOPHES project: Towards transnational comparability and reliability of human biomonitoring results
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Schindler, Birgit Karin, Esteban, Marta, Koch, Holger Martin, Castano, Argelia, Koslitz, Stephan, Cañas, Ana, Casteleyn, Ludwine, Kolossa-Gehring, Marike, Schwedler, Gerda, Schoeters, Greet, Hond, Elly Den, Sepai, Ovnair, Exley, Karen, Bloemen, Louis, Horvat, Milena, Knudsen, Lisbeth E., Joas, Anke, Joas, Reinhard, Biot, Pierre, Aerts, Dominique, Lopez, Ana, Huetos, Olga, Katsonouri, Andromachi, Maurer-Chronakis, Katja, Kasparova, Lucie, Vrbík, Karel, Rudnai, Peter, Naray, Miklos, Guignard, Cedric, Fischer, Marc E., Ligocka, Danuta, Janasik, Beata, Reis, M. Fátima, Namorado, Sónia, Pop, Cristian, Dumitrascu, Irina, Halzlova, Katarina, Fabianova, Eleonora, Mazej, Darja, Tratnik, Janja Snoj, Berglund, Marika, Jönsson, Bo, Lehmann, Andrea, Crettaz, Pierre, Frederiksen, Hanne, Nielsen, Flemming, McGrath, Helena, Nesbitt, Ian, De Cremer, Koen, Vanermen, Guido, Koppen, Gudrun, Wilhelm, Michael, Becker, Kerstin, and Angerer, Jürgen
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- 2014
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45. Ambient air pollution and low birthweight: a European cohort study (ESCAPE)
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Pedersen, Marie, Giorgis-Allemand, Lise, Bernard, Claire, Aguilera, Inmaculada, Andersen, Anne-Marie Nybo, Ballester, Ferran, Beelen, Rob M J, Chatzi, Leda, Cirach, Marta, Danileviciute, Asta, Dedele, Audrius, Eijsden, Manon van, Estarlich, Marisa, Fernández-Somoano, Ana, Fernández, Mariana F, Forastiere, Francesco, Gehring, Ulrike, Grazuleviciene, Regina, Gruzieva, Olena, Heude, Barbara, Hoek, Gerard, Hoogh, Kees de, van den Hooven, Edith H, Håberg, Siri E, Jaddoe, Vincent W V, Klümper, Claudia, Korek, Michal, Krämer, Ursula, Lerchundi, Aitana, Lepeule, Johanna, Nafstad, Per, Nystad, Wenche, Patelarou, Evridiki, Porta, Daniela, Postma, Dirkje, Raaschou-Nielsen, Ole, Rudnai, Peter, Sunyer, Jordi, Stephanou, Euripides, Sørensen, Mette, Thiering, Elisabeth, Tuffnell, Derek, Varró, Mihály J, Vrijkotte, Tanja G M, Wijga, Alet, Wilhelm, Michael, Wright, John, Nieuwenhuijsen, Mark J, Pershagen, Göran, Brunekreef, Bert, Kogevinas, Manolis, and Slama, Rémy
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- 2013
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46. Lung cancer risk among bakers, pastry cooks and confectionary makers: the SYNERGY study
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Behrens, Thomas, Kendzia, Benjamin, Treppmann, Tabea, Olsson, Ann, Jöckel, Karl-Heinz, Gustavsson, Per, Pohlabeln, Hermann, Ahrens, Wolfgang, Brüske, Irene, Wichmann, Hans-Erich, Merletti, Franco, Mirabelli, Dario, Richiardi, Lorenzo, Simonato, Lorenzo, Zaridze, David, Szeszenia-Dabrowska, Neonila, Rudnai, Peter, Lissowska, Jolanta, Fabianova, Eleonora, Tardón, Adonina, Field, John, Dumitru, Rodica Stanescu, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Siemiatycki, Jack, Parent, Marie-Elise, McLaughlin, John, Demers, Paul, Landi, Maria Teresa, Caporaso, Neil, Kromhout, Hans, Vermeulen, Roel, Peters, Susan, Benhamou, Simone, Stücker, Isabelle, Guida, Florence, Consonni, Dario, Bueno-de-Mesquita, Bas, Mannetje, Andrea 't, Pearce, Neil, Tse, Lap Ah, Yu, Ignatius Tak-sun, Plato, Nils, Boffetta, Paolo, Straif, Kurt, Schüz, Joachim, Pesch, Beate, and Brüning, Thomas
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- 2013
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47. The Influence of Meteorological Factors and Atmospheric Pollutants on the Risk of Preterm Birth
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Giorgis-Allemand, Lise, Pedersen, Marie, Bernard, Claire, Aguilera, Inmaculada, Beelen, Rob M. J., Chatzi, Leda, Cirach, Marta, Danileviciute, Asta, Dedele, Audrius, van Eijsden, Manon, Estarlich, Marisa, Fernández-Somoano, Ana, Fernández, Mariana F., Forastiere, Francesco, Gehring, Ulrike, Grazuleviciene, Regina, Gruzieva, Olena, Heude, Barbara, Hoek, Gerard, de Hoogh, Kees, van den Hooven, Edith H., Håberg, Siri E., Iñiguez, Carmen, Jaddoe, Vincent W. V., Korek, Michal, Lertxundi, Aitana, Lepeule, Johanna, Nafstad, Per, Nystad, Wenche, Patelarou, Evridiki, Porta, Daniela, Postma, Dirkje, Raaschou-Nielsen, Ole, Rudnai, Peter, Siroux, Valérie, Sunyer, Jordi, Stephanou, Euripides, Sørensen, Mette, Eriksen, Kirsten Thorup, Tuffnell, Derek, Varró, Mihály J., Vrijkotte, Tanja G. M., Wijga, Alet, Wright, John, Nieuwenhuijsen, Mark J., Pershagen, Göran, Brunekreef, Bert, Kogevinas, Manolis, and Slama, Rémy
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- 2017
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48. The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study
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Johansson, Mattias, Carreras-Torres, Robert, Scelo, Ghislaine, Purdue, Mark P., Mariosa, Daniela, Muller, David C., Timpson, Nicolas J., Haycock, Philip C., Brown, Kevin M., Wang, Zhaoming, Ye, Yuanqing, Hofmann, Jonathan N., Foll, Matthieu, Gaborieau, Valerie, Machiela, Mitchell J., Colli, Leandro M., Li, Peng, Garnier, Jean-Guillaume, Blanche, Helene, Boland, Anne, Burdette, Laurie, Prokhortchouk, Egor, Skryabin, Konstantin G., Yeager, Meredith, Radojevic-Skodric, Sanja, Ognjanovic, Simona, Foretova, Lenka, Holcatova, Ivana, Janout, Vladimir, Mates, Dana, Mukeriya, Anush, Rascu, Stefan, Zaridze, David, Bencko, Vladimir, Cybulski, Cezary, Fabianova, Eleonora, Jinga, Viorel, Lissowska, Jolanta, Lubinski, Jan, Navratilova, Marie, Rudnai, Peter, Benhamou, Simone, Cancel-Tassin, Geraldine, Cussenot, Olivier, Weiderpass, Elisabete, Ljungberg, Börje, Tumkur Sitaram, Raviprakash, Häggström, Christel, Bruinsma, Fiona, Jordan, Susan J., Severi, Gianluca, Winship, Ingrid, Hveem, Kristian, Vatten, Lars J., Fletcher, Tony, Larsson, Susanna C., Wolk, Alicja, Banks, Rosamonde E., Selby, Peter J., Easton, Douglas F., Andreotti, Gabriella, Beane Freeman, Laura E., Koutros, Stella, Männistö, Satu, Weinstein, Stephanie, Clark, Peter E., Edwards, Todd L., Lipworth, Loren, Gapstur, Susan M., Stevens, Victoria L., Carol, Hallie, Freedman, Matthew L., Pomerantz, Mark M., Cho, Eunyoung, Wilson, Kathryn M., Gaziano, J. Michael, Sesso, Howard D., Freedman, Neal D., Parker, Alexander S., Eckel-Passow, Jeanette E., Huang, Wen-Yi, Kahnoski, Richard J., Lane, Brian R., Noyes, Sabrina L., Petillo, David, Teh, Bin Tean, Peters, Ulrike, White, Emily, Anderson, Garnet L., Johnson, Lisa, Luo, Juhua, Buring, Julie, Lee, I-Min, Chow, Wong-Ho, Moore, Lee E., Eisen, Timothy, Henrion, Marc, Larkin, James, Barman, Poulami, Leibovich, Bradley C., Choueiri, Toni K., Lathrop, G. Mark, Deleuze, Jean-Francois, Gunter, Marc, McKay, James D., Wu, Xifeng, Houlston, Richard S., Chanock, Stephen J., Relton, Caroline, Richards, J. Brent, Martin, Richard M., Davey Smith, George, and Brennan, Paul
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Obesity -- Genetic aspects -- Complications and side effects ,Renal cell carcinoma -- Genetic aspects -- Development and progression -- Care and treatment ,Genetic markers -- Health aspects ,Etiology (Medicine) ,Genetics ,Carcinoma ,Cancer ,Type 2 diabetes ,Genomics ,Insulin ,Proxy ,Lipids ,Genomes ,Fasting ,Glucose ,Biological sciences - Abstract
Background Several obesity-related factors have been associated with renal cell carcinoma (RCC), but it is unclear which individual factors directly influence risk. We addressed this question using genetic markers as proxies for putative risk factors and evaluated their relation to RCC risk in a mendelian randomization (MR) framework. This methodology limits bias due to confounding and is not affected by reverse causation. Methods and findings Genetic markers associated with obesity measures, blood pressure, lipids, type 2 diabetes, insulin, and glucose were initially identified as instrumental variables, and their association with RCC risk was subsequently evaluated in a genome-wide association study (GWAS) of 10,784 RCC patients and 20,406 control participants in a 2-sample MR framework. The effect on RCC risk was estimated by calculating odds ratios (OR.sub.SD) for a standard deviation (SD) increment in each risk factor. The MR analysis indicated that higher body mass index increases the risk of RCC (OR.sub.SD : 1.56, 95% confidence interval [CI] 1.44-1.70), with comparable results for waist-to-hip ratio (OR.sub.SD : 1.63, 95% CI 1.40-1.90) and body fat percentage (OR.sub.SD : 1.66, 95% CI 1.44-1.90). This analysis further indicated that higher fasting insulin (OR.sub.SD : 1.82, 95% CI 1.30-2.55) and diastolic blood pressure (DBP; OR.sub.SD : 1.28, 95% CI 1.11-1.47), but not systolic blood pressure (OR.sub.SD : 0.98, 95% CI 0.84-1.14), increase the risk for RCC. No association with RCC risk was seen for lipids, overall type 2 diabetes, or fasting glucose. Conclusions This study provides novel evidence for an etiological role of insulin in RCC, as well as confirmatory evidence that obesity and DBP influence RCC risk., Author(s): Mattias Johansson 1,*, Robert Carreras-Torres 1, Ghislaine Scelo 1, Mark P. Purdue 2, Daniela Mariosa 1, David C. Muller 3, Nicolas J. Timpson 4, Philip C. Haycock 4, Kevin [...]
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- 2019
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49. Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium
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Coté, Michele L., Liu, Mei, Bonassi, Stefano, Neri, Monica, Schwartz, Ann G., Christiani, David C., Spitz, Margaret R., Muscat, Joshua E., Rennert, Gad, Aben, Katja K., Andrew, Angeline S., Bencko, Vladimir, Bickeböller, Heike, Boffetta, Paolo, Brennan, Paul, Brenner, Hermann, Duell, Eric J., Fabianova, Eleonora, Field, John K., Foretova, Lenka, Friis, Søren, Harris, Curtis C., Holcatova, Ivana, Hong, Yun-Chul, Isla, Dolores, Janout, Vladimir, Kiemeney, Lambertus A., Kiyohara, Chikako, Lan, Qing, Lazarus, Philip, Lissowska, Jolanta, Le Marchand, Loic, Mates, Dana, Matsuo, Keitaro, Mayordomo, Jose I., McLaughlin, John R., Morgenstern, Hal, Müeller, Heiko, Orlow, Irene, Park, Bernard J., Pinchev, Mila, Raji, Olaide Y., Rennert, Hedy S., Rudnai, Peter, Seow, Adeline, Stucker, Isabelle, Szeszenia-Dabrowska, Neonila, Dawn Teare, M., Tjønnelan, Anne, Ugolini, Donatella, van der Heijden, Henricus F.M., Wichmann, Erich, Wiencke, John K., Woll, Penella J., Yang, Ping, Zaridze, David, Zhang, Zuo-Feng, Etzel, Carol J., and Hung, Rayjean J.
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- 2012
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50. Inorganic Arsenic and Basal Cell Carcinoma in Areas of Hungary, Romania, and Slovakia: A Case-Control Study
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Leonardi, Giovanni, Vahter, Marie, Clemens, Felicity, Goessler, Walter, Gurzau, Eugen, Hemminki, Kari, Hough, Rupert, Koppova, Kvetoslava, Kumar, Rajiv, Rudnai, Peter, Surdu, Simona, and Fletcher, Tony
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- 2012
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