33 results on '"Ruel, Rejean"'
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2. Structure-based design of small molecule inhibitors of the cagT4SS ATPase Cagα of Helicobacter pylori
3. Identification of a Novel Cyclin K Degrader Molecule with Selective Anti-AML Activity
4. Disruption of Intracellular Metal Homeostasis As a Vulnerability in SF3B1 Mutated AML
5. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
6. 1023 – THE IMPORTANCE OF STEM CELL EXPANSION IN TOMORROW'S MEDICINE
7. Synthesis of Montelukast (MK-0476) metabolic oxidation products
8. Single-step preparation of 1-hydroxybisphosphonates via addition of dialkyl phosphite potassium anions to acid chlorides
9. Samarium(II) iodide-mediated synthesis of chlorohydrins
10. New class of biphenylene dibenzazocinones as potent ligands for the human EP 1 prostanoid receptor
11. Identification of 1-{2-[4-chloro-1′-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4′-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y1 antagonist as an antiplatelet agent
12. Potent P2Y1 urea antagonists bearing various cyclic amine scaffolds
13. New azole antagonists with high affinity for the P2Y1 receptor
14. Disruption of Intracellular Metal Homeostasis As a Vulnerability in SF3B1Mutated AML
15. Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)- N-(2-methyl-1 H-pyrrolo[2,3- b]pyridin-5-yl)pyrrolo[2,1- f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor
16. ChemInform Abstract: New Class of Biphenylene Dibenzazocinones as Potent Ligands for the Human EP1 Prostanoid Receptor.
17. ChemInform Abstract: Discovery and Preclinical Studies of 5‐Isopropyl‐6‐(5‐methyl‐1,3,4‐oxadiazol‐2‐yl)‐N‐(2‐methyl‐1H‐pyrrolo [2,3‐b]pyridin‐5‐yl)pyrrolo[2,1‐f][1,2,4]triazin‐4‐amine (BMS‐645737), an in vivo Active Potent VEGFR‐2 Inhibitor.
18. Synthesis of Functionalized 7‐Azaindoles via Directed ortho‐Metalations.
19. Concise and Efficient Synthesis of 4‐Fluoro‐1H‐pyrrolo[2,3‐b]pyridine.
20. β‐Alanine Dipeptides as MC4R Agonists.
21. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs
22. Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors
23. Synthesis of functionalized 7-azaindoles via directed ortho-metalations
24. β-Alanine dipeptides as MC4R agonists
25. Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis.
26. ChemInform Abstract: New Class of Biphenylene Dibenzazocinones as Potent Ligands for the Human EP1 Prostanoid Receptor.
27. Investigations of the intramolecular Ni(II)/Cr(II)-mediated coupling reaction: Application to the taxane ring system
28. Synthetic studies toward the taxane class of natural products
29. Synthesis of succinic diesters via reductive coupling of α-haloesters using samarium (II) iodide and HMPA
30. Convenient access to two enantiomeric oxirane synthons bearing a quaternary gem-dimethyl carbon center: Synthesis of 3S-(+) and 3R-(−)-2,2-dimethyl-3,4-oxo-1-butanol from R-(−)-pantolactone
31. ChemInform Abstract: New Class of Biphenylene Dibenzazocinones as Potent Ligands for the Human EP1Prostanoid Receptor.
32. Reduction of olefins on solid support using diimide
33. Identification of 1-{2-[4-chloro-1′-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4′-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y1 antagonist as an antiplatelet agent.
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