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13 results on '"Ruiz Cano, Rafael"'

1. Índice de masa triponderal y marcadores de riesgo metabólico en niños y adolescentes con obesidad

Author

Palomo Atance, Enrique, primary, Caballero Mora, Francisco Javier, additional, Espadas Maciá, David, additional, Marbán Calzón, Mercedes, additional, Sevilla Ramos, Pilar, additional, García Villaescusa, Lourdes, additional, Dabad Moreno, María Jesús, additional, Muñoz-Rodríguez, José Ramón, additional, and Ruiz Cano, Rafael, additional

Published
2023
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4. Novel mutations associated with nephrogenic diabetes insipidus. A clinical-genetic study

Author

García Castaño, Alejandro, Pérez de Nanclares, Gustavo, Madariaga, Leire, Aguirre, Mireia, Chocron, Sara, Madrid, Alvaro, Lafita Tejedor, Francisco Javier, Gil Campos, Mercedes, Sánchez del Pozo, Jaime, Ruiz Cano, Rafael, Espino, Mar, Gomez Vida, Jose Maria, Santos, Fernando, García Nieto, Victor Manuel, Loza, Reyner, Rodríguez, Luis Miguel, Hidalgo Barquero, Emilia, Printza, Nikoleta, Camacho, Juan Antonio, Castaño, Luis, Ariceta, Gema, and RenalTube Group

Published
2015
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13. [Estimated glucose disposal rate in patients under 18 years of age with type 1 diabetes mellitus and overweight or obesity].

Author

Palomo Atance E, Ballester Herrera MJ, Giralt Muiña P, Ruiz Cano R, León Martín A, and Giralt Muiña J

Subjects
Adolescent, Anthropometry, Blood Pressure, Child, Child, Preschool, Cross-Sectional Studies, Diabetes Mellitus, Type 1 complications, Diabetes Mellitus, Type 1 drug therapy, Female, Glycated Hemoglobin analysis, Humans, Hypertension complications, Insulin administration & dosage, Insulin classification, Insulin therapeutic use, Insulin Resistance, Lipids blood, Lipoproteins blood, Male, Metabolic Syndrome metabolism, Obesity complications, Obesity metabolism, Overweight complications, Prospective Studies, Sampling Studies, Waist-Hip Ratio, Diabetes Mellitus, Type 1 metabolism, Glucose metabolism, Overweight metabolism
Abstract

Objective: To assess the estimated glucose disposal rate (eGDR), insulin dose, and lipoprotein profile in children with type 1 diabetes mellitus (T1DM) and overweight or obesity as compared to children with T1DM and normal weight., Methods: A total of 115 patients (aged 5-16 years) with T1DM on intensive insulin therapy were recruited. The following parameters were measured: weight, height, body mass index, waist and hip circumference, insulin dose, eGDR, glycosylated hemoglobin, blood pressure, and lipoprotein profile. Results were stratified by sex and age., Results: No significant differences were found in eGDR between children with normal weight, overweight, and obesity. However, obese children older than 11 years had lower eGDR values (9.3±1.3 vs 10.1±0.8 mg kg(-1)min(-1); p<0.01). Insulin dose was higher in overweight and obese children, especially in IU/m2/day (37.7 vs 36.1 vs. 29.4 respectively; p<0.01). Obese children had higher low-density lipoprotein cholesterol levels than children with overweight and normal weight (106.5 vs 91.7 vs 91.5mg/dL respectively; p<0.01). No correlation was found between waist circumference and the different markers of insulin resistance., Conclusions: Values of eGDR values were lower in obese children with T1DM older than 11 years, and this may therefore be considered a marker of insulin resistance. Insulin dose was higher in diabetic patients with overweight or obesity, specially in IU/m2/day. Obese children with T1DM had a lipoprotein profile of cardiovascular risk., (Copyright © 2012 SEEN. Published by Elsevier Espana. All rights reserved.)

Published
2013
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