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117 results on '"Ryan J. Tibshirani"'

1. Evaluation of FluSight influenza forecasting in the 2021–22 and 2022–23 seasons with a new target laboratory-confirmed influenza hospitalizations

Author

Sarabeth M. Mathis, Alexander E. Webber, Tomás M. León, Erin L. Murray, Monica Sun, Lauren A. White, Logan C. Brooks, Alden Green, Addison J. Hu, Roni Rosenfeld, Dmitry Shemetov, Ryan J. Tibshirani, Daniel J. McDonald, Sasikiran Kandula, Sen Pei, Rami Yaari, Teresa K. Yamana, Jeffrey Shaman, Pulak Agarwal, Srikar Balusu, Gautham Gururajan, Harshavardhan Kamarthi, B. Aditya Prakash, Rishi Raman, Zhiyuan Zhao, Alexander Rodríguez, Akilan Meiyappan, Shalina Omar, Prasith Baccam, Heidi L. Gurung, Brad T. Suchoski, Steve A. Stage, Marco Ajelli, Allisandra G. Kummer, Maria Litvinova, Paulo C. Ventura, Spencer Wadsworth, Jarad Niemi, Erica Carcelen, Alison L. Hill, Sara L. Loo, Clifton D. McKee, Koji Sato, Claire Smith, Shaun Truelove, Sung-mok Jung, Joseph C. Lemaitre, Justin Lessler, Thomas McAndrew, Wenxuan Ye, Nikos Bosse, William S. Hlavacek, Yen Ting Lin, Abhishek Mallela, Graham C. Gibson, Ye Chen, Shelby M. Lamm, Jaechoul Lee, Richard G. Posner, Amanda C. Perofsky, Cécile Viboud, Leonardo Clemente, Fred Lu, Austin G. Meyer, Mauricio Santillana, Matteo Chinazzi, Jessica T. Davis, Kunpeng Mu, Ana Pastore y Piontti, Alessandro Vespignani, Xinyue Xiong, Michal Ben-Nun, Pete Riley, James Turtle, Chis Hulme-Lowe, Shakeel Jessa, V. P. Nagraj, Stephen D. Turner, Desiree Williams, Avranil Basu, John M. Drake, Spencer J. Fox, Ehsan Suez, Monica G. Cojocaru, Edward W. Thommes, Estee Y. Cramer, Aaron Gerding, Ariane Stark, Evan L. Ray, Nicholas G. Reich, Li Shandross, Nutcha Wattanachit, Yijin Wang, Martha W. Zorn, Majd Al Aawar, Ajitesh Srivastava, Lauren A. Meyers, Aniruddha Adiga, Benjamin Hurt, Gursharn Kaur, Bryan L. Lewis, Madhav Marathe, Srinivasan Venkatramanan, Patrick Butler, Andrew Farabow, Naren Ramakrishnan, Nikhil Muralidhar, Carrie Reed, Matthew Biggerstaff, and Rebecca K. Borchering

Subjects
Science
Abstract

Abstract Accurate forecasts can enable more effective public health responses during seasonal influenza epidemics. For the 2021–22 and 2022–23 influenza seasons, 26 forecasting teams provided national and jurisdiction-specific probabilistic predictions of weekly confirmed influenza hospital admissions for one-to-four weeks ahead. Forecast skill is evaluated using the Weighted Interval Score (WIS), relative WIS, and coverage. Six out of 23 models outperform the baseline model across forecast weeks and locations in 2021–22 and 12 out of 18 models in 2022–23. Averaging across all forecast targets, the FluSight ensemble is the 2nd most accurate model measured by WIS in 2021–22 and the 5th most accurate in the 2022–23 season. Forecast skill and 95% coverage for the FluSight ensemble and most component models degrade over longer forecast horizons. In this work we demonstrate that while the FluSight ensemble was a robust predictor, even ensembles face challenges during periods of rapid change.

Published
2024
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2. Results from the second year of a collaborative effort to forecast influenza seasons in the United States

Author

Matthew Biggerstaff, Michael Johansson, David Alper, Logan C. Brooks, Prithwish Chakraborty, David C. Farrow, Sangwon Hyun, Sasikiran Kandula, Craig McGowan, Naren Ramakrishnan, Roni Rosenfeld, Jeffrey Shaman, Rob Tibshirani, Ryan J. Tibshirani, Alessandro Vespignani, Wan Yang, Qian Zhang, and Carrie Reed

Subjects
Infectious and parasitic diseases, RC109-216
Abstract

Accurate forecasts could enable more informed public health decisions. Since 2013, CDC has worked with external researchers to improve influenza forecasts by coordinating seasonal challenges for the United States and the 10 Health and Human Service Regions. Forecasted targets for the 2014–15 challenge were the onset week, peak week, and peak intensity of the season and the weekly percent of outpatient visits due to influenza-like illness (ILI) 1–4 weeks in advance. We used a logarithmic scoring rule to score the weekly forecasts, averaged the scores over an evaluation period, and then exponentiated the resulting logarithmic score. Poor forecasts had a score near 0, and perfect forecasts a score of 1.Five teams submitted forecasts from seven different models. At the national level, the team scores for onset week ranged from

Published
2018
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16. Recalibrating probabilistic forecasts of epidemics.

Author

Aaron Rumack, Ryan J Tibshirani, and Roni Rosenfeld

Subjects
Biology (General), QH301-705.5
Abstract

Distributional forecasts are important for a wide variety of applications, including forecasting epidemics. Often, forecasts are miscalibrated, or unreliable in assigning uncertainty to future events. We present a recalibration method that can be applied to a black-box forecaster given retrospective forecasts and observations, as well as an extension to make this method more effective in recalibrating epidemic forecasts. This method is guaranteed to improve calibration and log score performance when trained and measured in-sample. We also prove that the increase in expected log score of a recalibrated forecaster is equal to the entropy of the PIT distribution. We apply this recalibration method to the 27 influenza forecasters in the FluSight Network and show that recalibration reliably improves forecast accuracy and calibration. This method, available on Github, is effective, robust, and easy to use as a post-processing tool to improve epidemic forecasts.

Published
2022
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25. Deep Quantile Aggregation.

Author

Taesup Kim, Rasool Fakoor, Jonas Mueller 0001, Alexander J. Smola, and Ryan J. Tibshirani

Published
2021

36. Collaborative Hubs: Making the Most of Predictive Epidemic Modeling

Author

Nicholas G, Reich, Justin, Lessler, Sebastian, Funk, Cecile, Viboud, Alessandro, Vespignani, Ryan J, Tibshirani, Katriona, Shea, Melanie, Schienle, Michael C, Runge, Roni, Rosenfeld, Evan L, Ray, Rene, Niehus, Helen C, Johnson, Michael A, Johansson, Harry, Hochheiser, Lauren, Gardner, Johannes, Bracher, Rebecca K, Borchering, and Matthew, Biggerstaff

Subjects
Opinions, Ideas, & Practice, Public Health, Environmental and Occupational Health, Humans, Epidemics
Published
2022
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39. Trend Filtering on Graphs.

Author

Yu-Xiang Wang 0003, James Sharpnack, Alexander J. Smola, and Ryan J. Tibshirani

Published
2016

44. A human judgment approach to epidemiological forecasting.

Author

David C Farrow, Logan C Brooks, Sangwon Hyun, Ryan J Tibshirani, Donald S Burke, and Roni Rosenfeld

Subjects
Biology (General), QH301-705.5
Abstract

Infectious diseases impose considerable burden on society, despite significant advances in technology and medicine over the past century. Advanced warning can be helpful in mitigating and preparing for an impending or ongoing epidemic. Historically, such a capability has lagged for many reasons, including in particular the uncertainty in the current state of the system and in the understanding of the processes that drive epidemic trajectories. Presently we have access to data, models, and computational resources that enable the development of epidemiological forecasting systems. Indeed, several recent challenges hosted by the U.S. government have fostered an open and collaborative environment for the development of these technologies. The primary focus of these challenges has been to develop statistical and computational methods for epidemiological forecasting, but here we consider a serious alternative based on collective human judgment. We created the web-based "Epicast" forecasting system which collects and aggregates epidemic predictions made in real-time by human participants, and with these forecasts we ask two questions: how accurate is human judgment, and how do these forecasts compare to their more computational, data-driven alternatives? To address the former, we assess by a variety of metrics how accurately humans are able to predict influenza and chikungunya trajectories. As for the latter, we show that real-time, combined human predictions of the 2014-2015 and 2015-2016 U.S. flu seasons are often more accurate than the same predictions made by several statistical systems, especially for short-term targets. We conclude that there is valuable predictive power in collective human judgment, and we discuss the benefits and drawbacks of this approach.

Published
2017
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45. Trend Filtering on Graphs.

Author

Yu-Xiang Wang 0003, James Sharpnack, Alexander J. Smola, and Ryan J. Tibshirani

Published
2015

46. Comparing trained and untrained probabilistic ensemble forecasts of COVID-19 cases and deaths in the United States

Author

Evan L. Ray, Logan C. Brooks, Jacob Bien, Matthew Biggerstaff, Nikos I. Bosse, Johannes Bracher, Estee Y. Cramer, Sebastian Funk, Aaron Gerding, Michael A. Johansson, Aaron Rumack, Yijin Wang, Martha Zorn, Ryan J. Tibshirani, and Nicholas G. Reich

Subjects
Methodology (stat.ME), FOS: Computer and information sciences, Business and International Management, Statistics - Methodology
Abstract

The U.S. COVID-19 Forecast Hub aggregates forecasts of the short-term burden of COVID-19 in the United States from many contributing teams. We study methods for building an ensemble that combines forecasts from these teams. These experiments have informed the ensemble methods used by the Hub. To be most useful to policy makers, ensemble forecasts must have stable performance in the presence of two key characteristics of the component forecasts: (1) occasional misalignment with the reported data, and (2) instability in the relative performance of component forecasters over time. Our results indicate that in the presence of these challenges, an untrained and robust approach to ensembling using an equally weighted median of all component forecasts is a good choice to support public health decision makers. In settings where some contributing forecasters have a stable record of good performance, trained ensembles that give those forecasters higher weight can also be helpful.

Published
2022

48. Post‐selection inference for changepoint detection algorithms with application to copy number variation data

Author

Max G'Sell, Sangwon Hyun, Kevin Lin, and Ryan J. Tibshirani

Subjects
FOS: Computer and information sciences, Statistics and Probability, DNA Copy Number Variations, Computer science, Inference, 01 natural sciences, General Biochemistry, Genetics and Molecular Biology, Methodology (stat.ME), 010104 statistics & probability, 03 medical and health sciences, symbols.namesake, Lasso (statistics), Copy-number variation, 0101 mathematics, Statistics - Methodology, 030304 developmental biology, Statistical hypothesis testing, Comparative Genomic Hybridization, 0303 health sciences, General Immunology and Microbiology, business.industry, Applied Mathematics, Sampling (statistics), Usability, Markov chain Monte Carlo, General Medicine, Markov Chains, symbols, General Agricultural and Biological Sciences, business, Monte Carlo Method, Algorithm, Algorithms, Importance sampling
Abstract

Changepoint detection methods are used in many areas of science and engineering, for example, in the analysis of copy number variation data to detect abnormalities in copy numbers along the genome. Despite the broad array of available tools, methodology for quantifying our uncertainty in the strength (or the presence) of given changepoints post-selection are lacking. Post-selection inference offers a framework to fill this gap, but the most straightforward application of these methods results in low-powered hypothesis tests and leaves open several important questions about practical usability. In this work, we carefully tailor post-selection inference methods toward changepoint detection, focusing on copy number variation data. To accomplish this, we study commonly used changepoint algorithms: binary segmentation, as well as two of its most popular variants, wild and circular, and the fused lasso. We implement some of the latest developments in post-selection inference theory, mainly auxiliary randomization. This improves the power, which requires implementations of Markov chain Monte Carlo algorithms (importance sampling and hit-and-run sampling) to carry out our tests. We also provide recommendations for improving practical useability, detailed simulations, and example analyses on array comparative genomic hybridization as well as sequencing data.

Published
2021
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49. Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States

Author

Estee Y. Cramer, Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Aaron Gerding, Tilmann Gneiting, Katie H. House, Yuxin Huang, Dasuni Jayawardena, Abdul H. Kanji, Ayush Khandelwal, Khoa Le, Anja Mühlemann, Jarad Niemi, Apurv Shah, Ariane Stark, Yijin Wang, Nutcha Wattanachit, Martha W. Zorn, Youyang Gu, Sansiddh Jain, Nayana Bannur, Ayush Deva, Mihir Kulkarni, Srujana Merugu, Alpan Raval, Siddhant Shingi, Avtansh Tiwari, Jerome White, Neil F. Abernethy, Spencer Woody, Maytal Dahan, Spencer Fox, Kelly Gaither, Michael Lachmann, Lauren Ancel Meyers, James G. Scott, Mauricio Tec, Ajitesh Srivastava, Glover E. George, Jeffrey C. Cegan, Ian D. Dettwiller, William P. England, Matthew W. Farthing, Robert H. Hunter, Brandon Lafferty, Igor Linkov, Michael L. Mayo, Matthew D. Parno, Michael A. Rowland, Benjamin D. Trump, Yanli Zhang-James, Samuel Chen, Stephen V. Faraone, Jonathan Hess, Christopher P. Morley, Asif Salekin, Dongliang Wang, Sabrina M. Corsetti, Thomas M. Baer, Marisa C. Eisenberg, Karl Falb, Yitao Huang, Emily T. Martin, Ella McCauley, Robert L. Myers, Tom Schwarz, Daniel Sheldon, Graham Casey Gibson, Rose Yu, Liyao Gao, Yian Ma, Dongxia Wu, Xifeng Yan, Xiaoyong Jin, Yu-Xiang Wang, YangQuan Chen, Lihong Guo, Yanting Zhao, Quanquan Gu, Jinghui Chen, Lingxiao Wang, Pan Xu, Weitong Zhang, Difan Zou, Hannah Biegel, Joceline Lega, Steve McConnell, V. P. Nagraj, Stephanie L. Guertin, Christopher Hulme-Lowe, Stephen D. Turner, Yunfeng Shi, Xuegang Ban, Robert Walraven, Qi-Jun Hong, Stanley Kong, Axel van de Walle, James A. Turtle, Michal Ben-Nun, Steven Riley, Pete Riley, Ugur Koyluoglu, David DesRoches, Pedro Forli, Bruce Hamory, Christina Kyriakides, Helen Leis, John Milliken, Michael Moloney, James Morgan, Ninad Nirgudkar, Gokce Ozcan, Noah Piwonka, Matt Ravi, Chris Schrader, Elizabeth Shakhnovich, Daniel Siegel, Ryan Spatz, Chris Stiefeling, Barrie Wilkinson, Alexander Wong, Sean Cavany, Guido España, Sean Moore, Rachel Oidtman, Alex Perkins, David Kraus, Andrea Kraus, Zhifeng Gao, Jiang Bian, Wei Cao, Juan Lavista Ferres, Chaozhuo Li, Tie-Yan Liu, Xing Xie, Shun Zhang, Shun Zheng, Alessandro Vespignani, Matteo Chinazzi, Jessica T. Davis, Kunpeng Mu, Ana Pastore y Piontti, Xinyue Xiong, Andrew Zheng, Jackie Baek, Vivek Farias, Andreea Georgescu, Retsef Levi, Deeksha Sinha, Joshua Wilde, Georgia Perakis, Mohammed Amine Bennouna, David Nze-Ndong, Divya Singhvi, Ioannis Spantidakis, Leann Thayaparan, Asterios Tsiourvas, Arnab Sarker, Ali Jadbabaie, Devavrat Shah, Nicolas Della Penna, Leo A. Celi, Saketh Sundar, Russ Wolfinger, Dave Osthus, Lauren Castro, Geoffrey Fairchild, Isaac Michaud, Dean Karlen, Matt Kinsey, Luke C. Mullany, Kaitlin Rainwater-Lovett, Lauren Shin, Katharine Tallaksen, Shelby Wilson, Elizabeth C. Lee, Juan Dent, Kyra H. Grantz, Alison L. Hill, Joshua Kaminsky, Kathryn Kaminsky, Lindsay T. Keegan, Stephen A. Lauer, Joseph C. Lemaitre, Justin Lessler, Hannah R. Meredith, Javier Perez-Saez, Sam Shah, Claire P. Smith, Shaun A. Truelove, Josh Wills, Maximilian Marshall, Lauren Gardner, Kristen Nixon, John C. Burant, Lily Wang, Lei Gao, Zhiling Gu, Myungjin Kim, Xinyi Li, Guannan Wang, Yueying Wang, Shan Yu, Robert C. Reiner, Ryan Barber, Emmanuela Gakidou, Simon I. Hay, Steve Lim, Chris Murray, David Pigott, Heidi L. Gurung, Prasith Baccam, Steven A. Stage, Bradley T. Suchoski, B. Aditya Prakash, Bijaya Adhikari, Jiaming Cui, Alexander Rodríguez, Anika Tabassum, Jiajia Xie, Pinar Keskinocak, John Asplund, Arden Baxter, Buse Eylul Oruc, Nicoleta Serban, Sercan O. Arik, Mike Dusenberry, Arkady Epshteyn, Elli Kanal, Long T. Le, Chun-Liang Li, Tomas Pfister, Dario Sava, Rajarishi Sinha, Thomas Tsai, Nate Yoder, Jinsung Yoon, Leyou Zhang, Sam Abbott, Nikos I. Bosse, Sebastian Funk, Joel Hellewell, Sophie R. Meakin, Katharine Sherratt, Mingyuan Zhou, Rahi Kalantari, Teresa K. Yamana, Sen Pei, Jeffrey Shaman, Michael L. Li, Dimitris Bertsimas, Omar Skali Lami, Saksham Soni, Hamza Tazi Bouardi, Turgay Ayer, Madeline Adee, Jagpreet Chhatwal, Ozden O. Dalgic, Mary A. Ladd, Benjamin P. Linas, Peter Mueller, Jade Xiao, Yuanjia Wang, Qinxia Wang, Shanghong Xie, Donglin Zeng, Alden Green, Jacob Bien, Logan Brooks, Addison J. Hu, Maria Jahja, Daniel McDonald, Balasubramanian Narasimhan, Collin Politsch, Samyak Rajanala, Aaron Rumack, Noah Simon, Ryan J. Tibshirani, Rob Tibshirani, Valerie Ventura, Larry Wasserman, Eamon B. O’Dea, John M. Drake, Robert Pagano, Quoc T. Tran, Lam Si Tung Ho, Huong Huynh, Jo W. Walker, Rachel B. Slayton, Michael A. Johansson, Matthew Biggerstaff, Nicholas G. Reich, Cramer, Estee Y [0000-0003-1373-3177], Ray, Evan L [0000-0003-4035-0243], Lopez, Velma K [0000-0003-2926-4010], Bracher, Johannes [0000-0002-3777-1410], Gneiting, Tilmann [0000-0001-9397-3271], Niemi, Jarad [0000-0002-5079-158X], White, Jerome [0000-0003-4148-8834], Woody, Spencer [0000-0002-2882-3450], Fox, Spencer [0000-0003-1969-3778], Gaither, Kelly [0000-0002-4272-175X], Meyers, Lauren Ancel [0000-0002-5828-8874], Tec, Mauricio [0000-0002-1853-5842], George, Glover E [0000-0003-4779-8702], Cegan, Jeffrey C [0000-0002-3065-3403], Hunter, Robert H [0000-0002-2382-7938], Lafferty, Brandon [0000-0002-2618-3787], Mayo, Michael L [0000-0001-9014-1859], Rowland, Michael A [0000-0002-6759-8225], Chen, Samuel [0000-0002-1070-9801], Salekin, Asif [0000-0002-0807-8967], Corsetti, Sabrina M [0000-0003-2216-2492], Falb, Karl [0000-0002-3465-3988], Huang, Yitao [0000-0001-7846-2174], Sheldon, Daniel [0000-0002-4257-2432], Guo, Lihong [0000-0003-4804-4005], Gu, Quanquan [0000-0001-9830-793X], Xu, Pan [0000-0002-2559-8622], Lega, Joceline [0000-0003-2064-229X], McConnell, Steve [0000-0002-0294-3737], Turner, Stephen D [0000-0001-9140-9028], Shi, Yunfeng [0000-0003-1700-6049], Walraven, Robert [0000-0002-5755-4325], van de Walle, Axel [0000-0002-3415-1494], Turtle, James A [0000-0003-0735-7769], Ben-Nun, Michal [0000-0002-9164-0008], Riley, Steven [0000-0001-7904-4804], Koyluoglu, Ugur [0000-0002-6286-351X], Cavany, Sean [0000-0002-2559-797X], España, Guido [0000-0002-9915-8056], Moore, Sean [0000-0001-9062-6100], Oidtman, Rachel [0000-0003-1773-9533], Perkins, Alex [0000-0002-7518-4014], Kraus, David [0000-0003-4376-3932], Cao, Wei [0000-0001-5640-0917], Lavista Ferres, Juan [0000-0002-9654-3178], Vespignani, Alessandro [0000-0003-3419-4205], Sinha, Deeksha [0000-0002-9788-728X], Perakis, Georgia [0000-0002-0888-9030], Bennouna, Mohammed Amine [0000-0002-9123-8588], Spantidakis, Ioannis [0000-0002-5149-6320], Tsiourvas, Asterios [0000-0002-2979-6300], Sarker, Arnab [0000-0003-1680-9421], Jadbabaie, Ali [0000-0003-1122-3069], Shah, Devavrat [0000-0003-0737-3259], Celi, Leo A [0000-0001-6712-6626], Osthus, Dave [0000-0002-4681-091X], Fairchild, Geoffrey [0000-0001-5500-8120], Mullany, Luke C [0000-0003-4668-9803], Rainwater-Lovett, Kaitlin [0000-0002-8707-7339], Lee, Elizabeth C [0000-0002-4156-9637], Dent, Juan [0000-0003-3154-0731], Hill, Alison L [0000-0002-6583-3623], Keegan, Lindsay T [0000-0002-8526-3007], Lemaitre, Joseph C [0000-0002-2677-6574], Truelove, Shaun A [0000-0003-0538-0607], Wills, Josh [0000-0001-7285-9349], Gao, Lei [0000-0002-4707-0933], Gu, Zhiling [0000-0002-8052-7608], Yu, Shan [0000-0002-0271-5726], Hay, Simon I [0000-0002-0611-7272], Murray, Chris [0000-0002-4930-9450], Stage, Steven A [0000-0001-5361-6464], Prakash, B Aditya [0000-0002-3252-455X], Rodríguez, Alexander [0000-0002-4313-9913], Xie, Jiajia [0000-0001-6530-2489], Keskinocak, Pinar [0000-0003-2686-546X], Baxter, Arden [0000-0002-6345-2229], Oruc, Buse Eylul [0000-0003-2431-3864], Sinha, Rajarishi [0000-0001-9157-674X], Yoder, Nate [0000-0003-4153-4722], Zhang, Leyou [0000-0002-2454-0082], Funk, Sebastian [0000-0002-2842-3406], Meakin, Sophie R [0000-0002-6385-2652], Sherratt, Katharine [0000-0003-2049-3423], Yamana, Teresa K [0000-0001-8349-3151], Pei, Sen [0000-0002-7072-2995], Shaman, Jeffrey [0000-0002-7216-7809], Li, Michael L [0000-0002-2456-4834], Bertsimas, Dimitris [0000-0002-1985-1003], Skali Lami, Omar [0000-0002-8208-3035], Soni, Saksham [0000-0002-8898-5726], Tazi Bouardi, Hamza [0000-0002-7871-325X], Wang, Yuanjia [0000-0002-1510-3315], McDonald, Daniel [0000-0002-0443-4282], Politsch, Collin [0000-0003-3727-9167], Rajanala, Samyak [0000-0002-5791-3789], Rumack, Aaron [0000-0002-9181-1794], Tibshirani, Ryan J [0000-0002-2158-8304], Drake, John M [0000-0003-4646-1235], Ho, Lam Si Tung [0000-0002-0453-8444], Slayton, Rachel B [0000-0003-4699-8040], Johansson, Michael A [0000-0002-5090-7722], Biggerstaff, Matthew [0000-0001-5108-8311], Reich, Nicholas G [0000-0003-3503-9899], and Apollo - University of Cambridge Repository

Subjects
model evaluation, Multidisciplinary, COVID-19, prediction, United States, Data Accuracy, 510 Mathematics, 360 Social problems & social services, weather, Humans, Public Health, ddc:510, ensemble forecast, Pandemics, Mathematics, Forecasting, Probability
Abstract

Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models provide specific, quantitative, and evaluable predictions that inform short-term decisions such as healthcare staffing needs, school closures, and allocation of medical supplies. Starting in April 2020, the US COVID-19 Forecast Hub ( https://covid19forecasthub.org/ ) collected, disseminated, and synthesized tens of millions of specific predictions from more than 90 different academic, industry, and independent research groups. A multimodel ensemble forecast that combined predictions from dozens of groups every week provided the most consistently accurate probabilistic forecasts of incident deaths due to COVID-19 at the state and national level from April 2020 through October 2021. The performance of 27 individual models that submitted complete forecasts of COVID-19 deaths consistently throughout this year showed high variability in forecast skill across time, geospatial units, and forecast horizons. Two-thirds of the models evaluated showed better accuracy than a naïve baseline model. Forecast accuracy degraded as models made predictions further into the future, with probabilistic error at a 20-wk horizon three to five times larger than when predicting at a 1-wk horizon. This project underscores the role that collaboration and active coordination between governmental public-health agencies, academic modeling teams, and industry partners can play in developing modern modeling capabilities to support local, state, and federal response to outbreaks.

Published
2022
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50. The US COVID-19 Trends and Impact Survey: Continuous real-time measurement of COVID-19 symptoms, risks, protective behaviors, testing, and vaccination

Author

Joshua A. Salomon, Alex Reinhart, Alyssa Bilinski, Eu Jing Chua, Wichada La Motte-Kerr, Minttu M. Rönn, Marissa B. Reitsma, Katherine A. Morris, Sarah LaRocca, Tamer H. Farag, Frauke Kreuter, Roni Rosenfeld, and Ryan J. Tibshirani

Subjects
Adult, Male, COVID-19 Vaccines, Multidisciplinary, Population Biology, Social Sciences, COVID-19, Biological Sciences, Middle Aged, Patient Acceptance of Health Care, United States, Young Adult, COVID-19 Testing, Cross-Sectional Studies, SARS-CoV2, Health Status Indicators, Humans, survey, Female, Epidemiologic Methods, Social Media, Aged
Abstract

Significance The US COVID-19 Trends and Impact Survey (CTIS) has operated continuously since April 6, 2020, collecting over 20 million responses. As the largest public health survey conducted in the United States to date, CTIS was designed to facilitate detailed demographic and geographic analyses, track trends over time, and accommodate rapid revision to address emerging priorities. Using examples of CTIS results illuminating trends in symptoms, risks, mitigating behaviors, testing, and vaccination in relation to evolving high-priority policy questions over 12 mo of the pandemic, we illustrate the value of online surveys for tracking patterns and trends in COVID outcomes as an adjunct to official reporting, and showcase unique insights that would not be visible through traditional public health reporting., The US COVID-19 Trends and Impact Survey (CTIS) is a large, cross-sectional, internet-based survey that has operated continuously since April 6, 2020. By inviting a random sample of Facebook active users each day, CTIS collects information about COVID-19 symptoms, risks, mitigating behaviors, mental health, testing, vaccination, and other key priorities. The large scale of the survey—over 20 million responses in its first year of operation—allows tracking of trends over short timescales and allows comparisons at fine demographic and geographic detail. The survey has been repeatedly revised to respond to emerging public health priorities. In this paper, we describe the survey methods and content and give examples of CTIS results that illuminate key patterns and trends and help answer high-priority policy questions relevant to the COVID-19 epidemic and response. These results demonstrate how large online surveys can provide continuous, real-time indicators of important outcomes that are not subject to public health reporting delays and backlogs. The CTIS offers high value as a supplement to official reporting data by supplying essential information about behaviors, attitudes toward policy and preventive measures, economic impacts, and other topics not reported in public health surveillance systems.

Published
2021
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