Search

Introducción: Las alteraciones mentales entre la población se han convertido en un problema de salud, en los adolescentes destaca la presencia de ansiedad, esta se presenta como un estado patológico que puede ocasionar disfunción física, psicológica y conductual afectando diferentes áreas de la vida. Objetivo: Identificar las manifestaciones psíquicas y somáticas de la ansiedad en adolescentes de secundaria; determinar la intensidad de la ansiedad y las diferencias por edad y sexo, e identificar la relación de la ansiedad con la edad. Metodología: Estudio correlacional, se llevó a cabo en una muestra de 312 adolescentes estudiantes de secundaria del estado de Puebla de 11 a 16 años, se realizó un muestreo aleatorio estratificado por grado y grupo escolar, se utilizó la Escala de Ansiedad de Hamilton, el estudio se apegó a la Ley General de Salud, se protegió la privacidad y confidencialidad de la información. Para el análisis estadístico se aplicó la Prueba de Chi Cuadrada y correlación de Spearman. Resultados: La mayoría de los adolescentes manifiestan síntomas psíquicos como dificultad en la concentración (57.5%) y somáticos sensaciones de calor y frío (52.8%) en el último mes y siete días; más del 40% de adolescentes presentan ansiedad moderada/severa, no se encontró diferencia estadísticamente significativa por edad y sexo, ni relación entre la ansiedad y edad (p >.05). Conclusiones: Los adolescentes mantienen manifestaciones psíquicas y somáticas de ansiedad desde edades tempranas que pueden generar alteraciones en diferentes áreas y etapas de la vida, es necesario realizar intervenciones de enfermería para prevenir complicaciones.

People with mental illnesses are at a higher risk than the general population of suffering from somatic diseases. However, they receive less attention from healthcare services. Some studies have indicated that this situation can be partially explained by the stigmatizing attitudes of health professionals, including nurses. With the objective to improve future nursing professionals’ attitudes towards people with mental illnesses, an intervention involving direct contact with people who had lived experience with mental illnesses was designed and its effectiveness was measured. It consisted of a single 90-min session involving a mental health professional, a person with a mental illness, and a family member of someone with a mental illness. The intervention was based on a structured script where they described their experiences with the illness and their history of recovery, and then, they had a discussion with the attendees. The effectiveness of this approach was measured through a quasi-experimental study with a pretest–post-test design. The differences in the scores obtained in the AQ-27-E questionnaire before and after the intervention indicated that there was a decrease in fear, feelings of danger, avoidance, segregation, and coercive attitudes, while positive feelings increased, including a tendency to help and compassion. These results are important for clinical practice because this intervention could improve the quality of care provided to people with mental illnesses. Sin financiación 2.383 JCR (2019) Q1, 9/121 Nursing 0.965 SJR (2019) Q1, 6/40 Psychiatric Mental Health No data IDR 2019 UEV

We investigated how somatic changes in HNSCC interact with environmental and host risk factors and whether they influence the risk of HNSCC occurrence and outcome. 180-paired samples diagnosed as HNSCC in two high incidence regions of Europe and South America underwent targeted sequencing (14 genes) and evaluation of copy number alterations (SCNAs). TP53, PIK3CA, NOTCH1, TP63 and CDKN2A were the most frequently mutated genes. Cases were characterized by a low copy number burden with recurrent focal amplification in 11q13.3 and deletion in 15q22. Cases with low SCNAs showed an improved overall survival. We found significant correlations with decreased overall survival between focal amplified regions 4p16, 10q22 and 22q11, and losses in 12p12, 15q14 and 15q22. The mutational landscape in our cases showed an association to both environmental exposures and clinical characteristics. We confirmed that somatic copy number alterations are an important predictor of HNSCC overall survival.