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168 results on '"SOLARI, Nicola"'

6. The role of sentinel node tumor burden in modeling the prognosis of melanoma patients with positive sentinel node biopsy: an Italian melanoma intergroup study (N = 2,086)

Author

Tropea, Saveria, Del Fiore, Paolo, Maurichi, Andrea, Patuzzo, Roberto, Santinami, Mario, Ribero, Simone, Quaglino, Pietro, Caliendo, Virginia, Borgognoni, Lorenzo, Sestini, Serena, Giudice, Giuseppe, Nacchiero, Eleonora, Caracò, Corrado, Cordova, Adriana, Solari, Nicola, Piazzalunga, Dario, Tauceri, Francesca, Carcoforo, Paolo, Lombardo, Maurizio, Cavallari, Sara, and Mocellin, Simone

Published
2022
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13. Prediction of Non-sentinel Node Status in Patients with Melanoma and Positive Sentinel Node Biopsy: An Italian Melanoma Intergroup (IMI) Study

Author

Rossi, Carlo Riccardo, Mocellin, Simone, Campana, Luca Giovanni, Borgognoni, Lorenzo, Sestini, Serena, Giudice, Giuseppe, Caracò, Corrado, Cordova, Adriana, Solari, Nicola, Piazzalunga, Dario, Carcoforo, Paolo, Quaglino, Pietro, Caliendo, Virginia, Ribero, Simone, and on behalf of the Italian Melanoma Intergroup (IMI)

Published
2017
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15. Supplementary Methods, Table 1, Figure Legends 1-7 from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

Author

Pietra, Gabriella, primary, Manzini, Claudia, primary, Rivara, Silvia, primary, Vitale, Massimo, primary, Cantoni, Claudia, primary, Petretto, Andrea, primary, Balsamo, Mirna, primary, Conte, Romana, primary, Benelli, Roberto, primary, Minghelli, Simona, primary, Solari, Nicola, primary, Gualco, Marina, primary, Queirolo, Paola, primary, Moretta, Lorenzo, primary, and Mingari, Maria Cristina, primary

Published
2023
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16. Supplementary Figure 5 from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

Author

Pietra, Gabriella, primary, Manzini, Claudia, primary, Rivara, Silvia, primary, Vitale, Massimo, primary, Cantoni, Claudia, primary, Petretto, Andrea, primary, Balsamo, Mirna, primary, Conte, Romana, primary, Benelli, Roberto, primary, Minghelli, Simona, primary, Solari, Nicola, primary, Gualco, Marina, primary, Queirolo, Paola, primary, Moretta, Lorenzo, primary, and Mingari, Maria Cristina, primary

Published
2023
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17. Data from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

Author

Pietra, Gabriella, primary, Manzini, Claudia, primary, Rivara, Silvia, primary, Vitale, Massimo, primary, Cantoni, Claudia, primary, Petretto, Andrea, primary, Balsamo, Mirna, primary, Conte, Romana, primary, Benelli, Roberto, primary, Minghelli, Simona, primary, Solari, Nicola, primary, Gualco, Marina, primary, Queirolo, Paola, primary, Moretta, Lorenzo, primary, and Mingari, Maria Cristina, primary

Published
2023
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18. Supplementary Figure 1 from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

Author

Pietra, Gabriella, primary, Manzini, Claudia, primary, Rivara, Silvia, primary, Vitale, Massimo, primary, Cantoni, Claudia, primary, Petretto, Andrea, primary, Balsamo, Mirna, primary, Conte, Romana, primary, Benelli, Roberto, primary, Minghelli, Simona, primary, Solari, Nicola, primary, Gualco, Marina, primary, Queirolo, Paola, primary, Moretta, Lorenzo, primary, and Mingari, Maria Cristina, primary

Published
2023
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19. Supplementary Figure 2 from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

Author

Pietra, Gabriella, primary, Manzini, Claudia, primary, Rivara, Silvia, primary, Vitale, Massimo, primary, Cantoni, Claudia, primary, Petretto, Andrea, primary, Balsamo, Mirna, primary, Conte, Romana, primary, Benelli, Roberto, primary, Minghelli, Simona, primary, Solari, Nicola, primary, Gualco, Marina, primary, Queirolo, Paola, primary, Moretta, Lorenzo, primary, and Mingari, Maria Cristina, primary

Published
2023
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20. Supplementary Figure 6 from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

Author

Pietra, Gabriella, primary, Manzini, Claudia, primary, Rivara, Silvia, primary, Vitale, Massimo, primary, Cantoni, Claudia, primary, Petretto, Andrea, primary, Balsamo, Mirna, primary, Conte, Romana, primary, Benelli, Roberto, primary, Minghelli, Simona, primary, Solari, Nicola, primary, Gualco, Marina, primary, Queirolo, Paola, primary, Moretta, Lorenzo, primary, and Mingari, Maria Cristina, primary

Published
2023
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21. Supplementary Figure 3 from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

Author

Pietra, Gabriella, primary, Manzini, Claudia, primary, Rivara, Silvia, primary, Vitale, Massimo, primary, Cantoni, Claudia, primary, Petretto, Andrea, primary, Balsamo, Mirna, primary, Conte, Romana, primary, Benelli, Roberto, primary, Minghelli, Simona, primary, Solari, Nicola, primary, Gualco, Marina, primary, Queirolo, Paola, primary, Moretta, Lorenzo, primary, and Mingari, Maria Cristina, primary

Published
2023
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22. Supplementary Figure 4 from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

Author

Pietra, Gabriella, primary, Manzini, Claudia, primary, Rivara, Silvia, primary, Vitale, Massimo, primary, Cantoni, Claudia, primary, Petretto, Andrea, primary, Balsamo, Mirna, primary, Conte, Romana, primary, Benelli, Roberto, primary, Minghelli, Simona, primary, Solari, Nicola, primary, Gualco, Marina, primary, Queirolo, Paola, primary, Moretta, Lorenzo, primary, and Mingari, Maria Cristina, primary

Published
2023
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23. Supplementary Figure 7 from Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

Author

Pietra, Gabriella, primary, Manzini, Claudia, primary, Rivara, Silvia, primary, Vitale, Massimo, primary, Cantoni, Claudia, primary, Petretto, Andrea, primary, Balsamo, Mirna, primary, Conte, Romana, primary, Benelli, Roberto, primary, Minghelli, Simona, primary, Solari, Nicola, primary, Gualco, Marina, primary, Queirolo, Paola, primary, Moretta, Lorenzo, primary, and Mingari, Maria Cristina, primary

Published
2023
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24. Behavioral, neural and ultrastructural alterations in a graded-dose 6-OHDA mouse model of early-stage Parkinson's disease

Author

Slezia, Andrea, primary, Hegedus, Panna, additional, Rusina, Evgeniia, additional, Lengyel, Katalin, additional, Solari, Nicola, additional, Kaszas, Attila, additional, Balazsfi, Diana, additional, Botzanowski, Boris, additional, Acerbo, Emma, additional, MISSEY, Florian, additional, Williamson, Adam, additional, and Hangya, Balazs, additional

Published
2023
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25. Whole-Exome Sequencing and cfDNA Analysis Uncover Genetic Determinants of Melanoma Therapy Response in a Real-World Setting

Author

Vanni, Irene, primary, Pastorino, Lorenza, additional, Tanda, Enrica Teresa, additional, Andreotti, Virginia, additional, Dalmasso, Bruna, additional, Solari, Nicola, additional, Mascherini, Matteo, additional, Cabiddu, Francesco, additional, Guadagno, Antonio, additional, Coco, Simona, additional, Allavena, Eleonora, additional, Bruno, William, additional, Pietra, Gabriella, additional, Croce, Michela, additional, Gangemi, Rosaria, additional, Piana, Michele, additional, Zoppoli, Gabriele, additional, Ferrando, Lorenzo, additional, Spagnolo, Francesco, additional, Queirolo, Paola, additional, and Ghiorzo, Paola, additional

Published
2023
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26. Understanding Cognitive Deficits in Parkinson's Disease: Lessons from Preclinical Animal Models

Author

Solari, Nicola, Bonito-Oliva, Alessandra, and Fisone, Gilberto

Abstract

Parkinson's disease (PD) has been, until recently, mainly defined by the presence of characteristic motor symptoms, such as rigidity, tremor, bradykinesia/akinesia, and postural instability. Accordingly, pharmacological and surgical treatments have so far addressed these motor disturbances, leaving nonmotor, cognitive deficits an unmet clinical condition. At the preclinical level, the large majority of studies aiming at defining mechanisms and testing novel therapies have similarly focused on the motor aspects of PD. Unfortunately, deterioration of the executive functions, such as attention, recognition, working memory, and problem solving, often appear in an early, premotor phase of the disease and progressively increase in intensity, negatively affecting the quality of life of ~50%-60% of PD patients. At present, the cellular mechanisms underlying cognitive impairments in PD patients are largely unknown and an adequate treatment is still missing. The preclinical research has recently developed new animal models that may open new perspectives for a more integrated approach to the treatment of both motor and cognitive symptoms of the disease. This review will provide an overview on the cognitive symptoms occurring in early PD patients and then focus on the rodent and nonhuman primate models so far available for the study of discriminative and spatial memory attention and learning abilities related to this pathological condition.

Published
2013
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27. Prognostic Role of Multiple Lymphatic Basin Drainage in Sentinel Lymph Node-Negative Trunk Melanoma Patients: A Multicenter Study from the Italian Melanoma Intergroup

Author

Ribero, Simone, Osella-Abate, Simona, Pasquali, Sandro, Rossi, Carlo Riccardo, Borgognoni, Lorenzo, Piazzalunga, Dario, Solari, Nicola, Schiavon, Mauro, Brandani, Paola, Ansaloni, Luca, Ponte, Erica, Silan, Francesco, Sommariva, Antonio, Bellucci, Francesco, Macripò, Giuseppe, and Quaglino, Pietro

Published
2016
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31. A multicenter retrospective study on 4480 implanted PICC-ports: A GAVeCeLT project

Author

Bertoglio, Sergio, primary, Annetta, Maria Giuseppina, additional, Brescia, Fabrizio, additional, Emoli, Alessandro, additional, Fabiani, Fabio, additional, Fino, Maria, additional, Merlicco, Domenico, additional, Musaro, Andrea, additional, Orlandi, Marina, additional, Parisella, Laura, additional, Pinelli, Fulvio, additional, Reina, Simona, additional, Selmi, Valentina, additional, Solari, Nicola, additional, Tricarico, Fausto, additional, and Pittiruti, Mauro, additional

Published
2022
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32. The Role Of Sentinel Node Tumor Burden In Modeling The Prognosis Of Melanoma Patients With Positive Sentinel Node Biopsy: An Italian Melanoma Intergroup Study (N=2,086)

Author

Tropea, Saveria, primary, Fiore, Paolo Del, additional, Maurichi, Andrea, additional, Patuzzo, Roberto, additional, Santinami, Mario, additional, Ribero, Simone, additional, Quaglino, Pietro, additional, Caliendo, Virginia, additional, Borgognoni, Lorenzo, additional, Sestini, Serena, additional, Giudice, Giuseppe, additional, Nacchiero, Eleonora, additional, Caracò, Corrado, additional, Cordova, Adriana, additional, Solari, Nicola, additional, Piazzalunga, Dario, additional, Tauceri, Francesca, additional, Carcoforo, Paolo, additional, Lombardo, Maurizio, additional, Cavallari, Sara, additional, and Mocellin, Simone, additional

Published
2021
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43. In Vivo Localization of Deep Brain Implants in Mice

Author

Király, Bálint, primary, Balázsfi, Diána, additional, Horváth, Ildikó, additional, Solari, Nicola, additional, Sviatkó, Katalin, additional, Lengyel, Katalin, additional, Birtalan, Eszter, additional, Máthé, Domokos, additional, Szigeti, Krisztián, additional, and Hangya, Balázs, additional

Published
2020
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45. The critical view of safety during laparoscopic cholecystectomy: Strasberg Yes or No? An Italian Multicentre study.

Author

Sgaramella, Lucia Ilaria, Gurrado, Angela, Pasculli, Alessandro, de Angelis, Nicola, Memeo, Riccardo, Prete, Francesco Paolo, Berti, Stefano, Ceccarelli, Graziano, Rigamonti, Marco, Badessi, Francesco Giuseppe Aldo, Solari, Nicola, Milone, Marco, Catena, Fausto, Scabini, Stefano, Vittore, Francesco, Perrone, Gennaro, de Werra, Carlo, Cafiero, Ferdinando, Testini, Mario, and SYoN Italian Collaborative Group

Subjects
CHOLECYSTECTOMY, LAPAROSCOPIC surgery, SURGICAL complications, BILE ducts, HEMORRHAGE, PREVENTION of surgical complications, RESEARCH, RESEARCH methodology, MEDICAL cooperation, EVALUATION research, BILE duct diseases, COMPARATIVE studies, PSYCHOLOGICAL tests, GALLBLADDER
Abstract

Background: Laparoscopic cholecystectomy is considered the gold standard for the treatment of gallbladder lithiasis; nevertheless, the incidence of bile duct injuries (BDI) is still high (0.3-0.8%) compared to open cholecystectomy (0.2%). In 1995, Strasberg introduced the "Critical View of Safety" (CVS) to reduce the risk of BDI. Despite its widespread use, the scientific evidence supporting this technique to prevent BDI is controversial.Methods: Between March 2017 and March 2019, the data of patients submitted to laparoscopic cholecystectomy in 30 Italian surgical departments were collected on a national database. A survey was submitted to all members of Italian Digestive Pathology Society to obtain data on the preoperative workup, the surgical and postoperative management of patients and to judge, at the end of the procedure, if the isolation of the elements was performed according to the CVS. In the case of a declared critical view, iconographic documentation was obtained, finally reviewed by an external auditor.Results: Data from 604 patients were analysed. The study population was divided into two groups according to the evidence (Group A; n = 11) or absence (Group B; N = 593) of BDI and perioperative bleeding. The non-use of CVS was found in 54.6% of procedures in the Group A, and 25.8% in the Group B, and evaluating the operator-related variables the execution of CVS was associated with a significantly lower incidence of BDI and intraoperative bleeding.Conclusions: The CVS confirmed to be the safest technique to recognize the elements of the Calot triangle and, if correctly performed, it significantly impacted on preventing intraoperative complications. Additional educational programs on the correct application of CVS in clinical practice would be desirable to avoid extreme conditions that may require additional procedures. [ABSTRACT FROM AUTHOR]

Published
2021
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48. Lymph-Node Ratio in Patients with Cutaneous Melanoma: A Multi-Institution Prognostic Study

Author

Caracò Corrado, Maurichi Andrea, Ribero Simone, Marone Ugo, Santinami Mario, Borgognoni Lorenzo, Pasquali Sandro, Mocellin Simone, Mascheroni Luigi, Rossi Riccardo, Giudice Giuseppe, Piazzalunga Dario, Patuzzo Roberto, Solari Nicola, Macripò Giuseppe, and Mozzillo Nicola

Subjects
Oncology, Adult, Male, medicine.medical_specialty, Skin Neoplasms, Metastasis, Internal medicine, medicine, Humans, Survival rate, Lymph node, Melanoma, Survival analysis, Aged, Retrospective Studies, Neoplasm Staging, Female, Follow-Up Studies, Lymph Node Excision, Lymph Nodes, Lymphatic Metastasis, Middle Aged, Prognosis, Survival Rate, Surgery, business.industry, Hazard ratio, Cancer, medicine.disease, medicine.anatomical_structure, Cutaneous melanoma, business
Abstract

Lymph node ratio (LNR)—the number of metastatic lymph nodes (LNs) over the number of excised LNs after lymphadenectomy—is a prognostic factor for many solid tumors, but controversies still exist for skin melanoma. We investigated the prognostic relevance of LNR in melanoma patients and formulated a proposal for considering the LNR in the current American Joint Committee on Cancer (AJCC) N staging system. Retrospective data of 2,526 melanoma patients with LN metastasis from nine Italian institutions were collected in a multicenter database. The prognostic value of the LNR (categorized as A, ≤0.1; B, 0.11–0.25; and C, >0.25) was assessed by multivariable survival analysis. LNR was a significant independent prognostic factor for melanoma-specific survival (LNR B vs. A: hazard ratio [HR] 1.47, 95 % CI 1.16–1.87, p = 0.002; LNR C vs. A: HR 1.84, 95 % CI 1.29–2.61, p = 0.001). The LNR had prognostic value in patients with AJCC N1a (one positive LN after sentinel LN biopsy [SLNB], HR 2.33, 95 % CI 1.49–3.63, p

Published
2015

50. Severe Intellectual Disability and Enhanced Gamma-Aminobutyric Acidergic Synaptogenesis in a Novel Model of Rare RASopathies

Author

Papale, Alessandro, primary, d’Isa, Raffaele, additional, Menna, Elisabetta, additional, Cerovic, Milica, additional, Solari, Nicola, additional, Hardingham, Neil, additional, Cambiaghi, Marco, additional, Cursi, Marco, additional, Barbacid, Mariano, additional, Leocani, Letizia, additional, Fasano, Stefania, additional, Matteoli, Michela, additional, and Brambilla, Riccardo, additional

Published
2017
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