1. Successful Open Repair of a Thoracoabdominal Aortic Aneurysm After Multiple Failed Endovascular Treatments in a 22-Years-Old Individual With Loeys-Dietz Syndrome.
- Author
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Santoro, Annarita, Rizk, Mohamed, Inga Tavara, Laura, Ramadan, Moh'd Shafiq, and Melissano, Germano
- Subjects
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AORTIC valve diseases , *CAROTID artery , *ENDOVASCULAR aneurysm repair , *SOMATOSENSORY evoked potentials , *ABDOMINAL surgery , *AORTIC diseases , *BLOOD vessels , *COMPUTED tomography , *EVOKED potentials (Electrophysiology) , *BLOOD vessel prosthesis , *TREATMENT effectiveness , *MITRAL valve prolapse , *CORONARY artery bypass , *SURGICAL complications , *LOEYS-Dietz syndrome , *THORACOABDOMINAL aortic aneurysms , *TREATMENT failure , *GENETIC mutation , *GENERAL anesthesia , *GENETIC testing , *ECHOCARDIOGRAPHY , *AORTIC valve insufficiency , *BRACHIOCEPHALIC trunk , *PARALYSIS , *CEREBROSPINAL fluid shunts ,SUBCLAVIAN artery surgery - Abstract
Loeys-Dietz syndrome is a rare genetically triggered disease characterized by aortic involvement, predisposing individuals to aneurysm and dissection at young age. Open repair is considered the treatment of choice despite the fact that it is associated with significant morbidity and mortality rates. On the other hand, endovascular treatment may be also considered an acceptable option in specific cases such as emergency or in patients unfit for open surgery or when landing zones are within surgical grafts. We report the case of a thoracoabdominal aortic aneurysm (TAAA) open surgical repair (OSR) in a 22-year-old male patient diagnosed with type 2 Loeys-Dietz syndrome, treated by means of a TAAA replacement with a 30-mm multi-branched "Coselli" aortic graft (Vascutek, Renfrewshire, Scotland, UK) after multiple previously interventions, including a thoracic endovascular aortic repair (TEVAR) and a custom made endograft for the visceral aorta. [ABSTRACT FROM AUTHOR]
- Published
- 2025
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