1. Asymmetric Access to Chiral Sulfinyl Compounds as Bioisosteres of Carbonyl Compounds.
- Author
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Wang, Chenxin, Wu, Xinyu, Huang, Jiapian, Liu, Gang, and Wu, Jie
- Subjects
- *
SULFINYL compounds , *CARBONYL compounds , *ASYMMETRIC synthesis , *CARBONYL group , *SULFINAMIDES - Abstract
The sulfinyl group, as one of the bioisosteres of carbonyl groups, attracts considerable attention in the field of synthetic chemistry. In particular, the asymmetric construction of chiral sulfinyl compounds and their derivatives remains in the early stages of development. Sulfinyl compounds mainly include sulfoxides, sulfinate esters and sulfinamides, according to the different functional groups connected to the sulfur atom. This Review summarizes the fascinating recent progress made over the past decade on the asymmetric synthesis of enantiopure sulfinyl derivatives. 1 Introduction 2 Asymmetric Synthesis of Chiral Sulfoxides 3 Asymmetric Synthesis of Chiral Sulfinate Esters 4 Asymmetric Synthesis of Chiral Sulfinamides 5 Conclusion and Outlook [ABSTRACT FROM AUTHOR]
- Published
- 2024
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