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Introduction and aims: Hepatocellular carcinoma (HCC) is a primary malignant tumor of liver epithelial cells and is the most frequent primary liver cancer. The broadening of transplantation and resectability criteria has made therapeutic decisions more complex. Our aim was to describe the clinical and survival characteristics of patients with HCC treated through resection or liver transplantation at our hospital and identify the presence of factors that enable outcome prediction and facilitate therapeutic decision-making. Materials and methods: Patients with HCC that underwent surgery with curative intent at the Hospital Universitario Marqués de Valdecilla, within the time frame of 2007 and 2017, were retrospectively identified. Survival, mortality, disease-free interval, and different outcome-related variables were analyzed. Results: Ninety-six patients with a mean follow-up after surgery of 44 months were included. Overall mortality and recurrence were higher in the resection group. Mean survival was 51.4 months in the liver transplantation group and 37.5 months in the resection group, and the disease-free interval was 49.4 ± 37.2 and 27.4 ± 28.7 months, respectively (p = 0.002). The tumor burden score was statistically significant regarding risk for recurrence and specific mortality. Conclusions: There appears to be no patient subgroup in whom the results of surgical resection were superior or comparable to those of transplantation. Tumor burden determination could be a useful tool for patient subclassification and help guide therapeutic decision-making. Resumen: Introducción y objetivos: El carcinoma hepatocelular (CHC) es una neoplasia maligna primaria de células epiteliales hepáticas que constituye la neoplasia primaria hepática más frecuente. La ampliación de criterios de trasplante y resecabilidad han hecho más complejas las decisiones terapéuticas. Nos proponemos describir las características clínicas y supervivencia de los pacientes con CHC tratados mediante resección (RH) o trasplante hepático (THO) en nuestro Hospital, e identificar la presencia de factores que permitan predecir el pronóstico y facilitar las decisiones terapéuticas. Material y métodos: Se identificaron retrospectivamente los pacientes con CHC intervenidos con intención curativa en el Hospital Universitario Marqués de Valdecilla entre 2007 y 2017. Se analizaron la supervivencia, mortalidad, intervalo libre de enfermedad, así como distintas variables relacionadas con el pronóstico. Resultados: Se registraron 96 pacientes con un seguimiento medio tras cirugía de 44 meses. La mortalidad global y la recidiva fueron superiores en el grupo de resección. La supervivencia media fue de 51.4 meses en el grupo de TOH y de 37.5 meses en el de resección y el tiempo libre de enfermedad alcanzó los 49.4 ± 37.2 y 27.4 ± 28.7 meses, respectivamente (p: 0.002). La carga tumoral, valorada a través del “tumor burden score”, presentó una relación significativa con el riesgo de recidiva y la mortalidad específica. Conclusiones: No parece existir un subgrupo de pacientes en los que la resección quirúrgica presente resultados de supervivencia superiores o equiparables al trasplante. La carga tumoral podría ser una herramienta útil para subclasificar y ayudar a guiar las decisiones terapéuticas.

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction. Cancer survivorship in Mexico is a research topic that is still in its infancy. No specific studies have been found on the needs of this population, meaning that there are no validated scales in the Mexican population measuring the needs of cancer survivors. Objective. To validate and adapt the Cancer Survivors' Unmet Needs survey, Spanish version (CaSUN-Mx) for use in the Mexican adult oncology population. Method. One hundred and eighty participants answered the questionnaire (CaSUN-S). For the analysis, the study was divided into three phases: content validity, construct validity, and internal consistency analysis. Results. The final version of the adapted questionnaire (CaSUN-Mx) has 34 items and one open question. It was divided into five factors with a total Cronbach's Alpha of .95 and a value of over .85, in all the subscales (psychological care, comprehensive and collaborative care, practical and information needs, and those associated with effects. Discussion and conclusion. The CaSUN-Mx questionnaire has content validity because it has been adequately linguistically and culturally adapted, and construct validity because of its factorial structure, and reliability, making it suitable for use in the Mexican adult oncology population. [ABSTRACT FROM AUTHOR]

Copyright of Acta Medica Colombiana is the property of Acta Medica Colombiana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Enfermería Nefrológica is the property of Sociedad Espanola de Enfermeria Nefrologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Nutrición Clínica y Dietética Hospitalaria is the property of Sociedad Espanola de Dietetica y Ciencias de la Alimentacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Cuadernos del Centro de Estudios de Diseño y Comunicación is the property of Cuadernos del Centro de Estudios de Diseno y Comunicacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of GeSec: Revista de Gestao e Secretariado is the property of Sindicato das Secretarias e Secretarios do Estado de Sao Paulo (SINSESP) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Antecedentes: El copal es una resina que se usa en ceremonias religiosas y culturales; se extrae de Bursera bipinnata y Bursera copallifera y se obtiene tanto de poblaciones silvestres como de árboles manejados. Preguntas: ¿Qué método de propagación (estacas o semillas) resulta más adecuado para cada especie? ¿Cómo es el desempeño en campo en términos de supervivencia y crecimiento de estacas y plántulas de cada especie? Especies de estudio: Bursera bipinnata y B. copallifera Sitio y años de estudio: Santiago Tepetlapa, Morelos 2016-2018 Métodos: Las plantas se propagaron en 2015-2016. En 2016 se trasplantaron 133 plantas: 42 estacas y 27 plántulas de B. bipinnata y 26 y 38 respectivamente de B. copallifera. Se evaluó su crecimiento durante un año y la supervivencia durante dos. Se midió la tasa relativa de crecimiento (TRC) y la asignación de biomasa a distintos órganos. Resultados: En B. bipinnata es más factible la propagación por estacas y en B. copallifera por semillas. El primer año las estacas tuvieron una mayor supervivencia que las plántulas, pero en el segundo fue mayor en las estacas de B. bipinnata (65 %), que en el resto de las plantas (< 15 %). Se registraron diferencias entre especies en la asignación final de biomasa en las estacas, pero no en plántulas; la TRC no difirió entre especies. Conclusiones: Las estacas presentaron mejor desempeño que las plántulas; en particular las de B. bipinnata. Estos resultados pueden contribuir al establecimiento de plantaciones de estas especies en sistemas agroforestales y con fines de restauración.

Introducción: El fallo primario incluye la trombosis precoz y los fallos de maduración. Objetivos: Determinar los factores de riesgo asociados al fallo primario de fístulas nativas y su relación con la supervivencia. Analizar las diferencias ecográficas entre fístulas maduras y fístulas con fallos de maduración. Material y Método: Estudio observacional y retrospectivo. Variables: sociodemográficas, antropométricas, comorbilidades, parámetros sanguíneos y ecográficos. Análisis estadístico: Descriptivo. Regresión logística. Método de Kaplan-Meier. Resultados: Muestra 65 fístulas nativas, 72,3% hombres. Edad 69,7 años. 60% fístulas maduras y 40% fístulas con fallo primario (20% fallo de maduración y 20% trombosis precoz). Factores de riesgo de fallos maduración: diámetros arteriales

Objetivos: comprender el sentido de las experiencias de las pacientes con cáncer de mama que asisten a los procesos de diagnóstico y tratamiento. Materiales y métodos: estudio descriptivo cualitativo desde el paradigma científico hermenéutico-interpretativo, a partir de la base epistemológica fenomenológica. Incluyó mujeres de 18 años o más con diagnóstico de cáncer de mama, atendidas en una clínica universitaria en Bogotá, a quienes se les realizó una entrevista semiestructurada. Procedimiento: entrevistas semiestructuradas a partir de categorías preestablecidas. Aspectos evaluados: conocimiento sobre los patrones actuales de tamización y detección del cáncer de mama, patrones actuales de utilización de la atención médica y las necesidades sanitarias percibidas. Resultados: con respecto a los Patrones actuales de conocimiento de tamización y detección del cáncer de mama, las pacientes evidenciaron contar con poco conocimiento. Acerca de los Patrones actuales de utilización de la atención médica, se evidenciaron inconformidades con el proceso administrativo. En cuanto a las necesidades sanitarias percibidas, se encontró un sentimiento de abandono generado por la falta de continuidad del proceso de atención. Adicionalmente, se encontraron como categorías emergentes: La confianza en el sistema de atención y La predisposición por sentimientos de culpa ante el desconocimiento de la patología. Conclusiones: se requiere un proceso de atención general que responda a las necesidades médicas reales de las pacientes, más allá de lo administrativo, enfocado en la calidad de la relación médico-paciente de todo el equipo multidisciplinario.

Long-lived territorial bird populations often consist of a few territorial breeding adults and many nonbreeding individuals. Some populations are threatened by anthropogenic activities, because of human conflicts for high-quality breeding habitat. Therefore, habitat restoration projects have been widely implemented to improve avian population status. In conjunction with habitat restoration, conservation translocations have been increasingly implemented. Adequate nonbreeder survival can be a key factor in the success of these attempts because nonbreeding birds may represent reservoirs for the replacement of breeders. The maintenance of breeding pair numbers is also influenced by the transition rate of nonbreeders to breeders. The reintroduction of Oriental Stork (Ciconia boyciana), a long-lived, territorial, endangered species, was initiated in Japan in 2005 using captive birds in hopes of increasing the population's use of restored habitat. Our objective of this study was to elucidate the factors determining reintroduced stork survival and recruitment to the breeding populations. We estimated the survival rate and breeding participation rate by sex, age, generation, wild-born or not, haplotypes, and breeding status in storks reintroduced during 2005–2022 using Bayesian hierarchical models. There was no significant difference in survival rate between nonbreeders and breeders. However, the survival rate was lower in wild-born birds than released birds, which may be related to the longer-distance natal dispersal of new generations. Accelerated habitat restoration around breeding areas and preventive measures for collision with human-built structures should be implemented for the sustained growth of reintroduced populations. A low survival rate was also detected for a specific mitochondrial DNA (mtDNA) haplotype that accounts for the majority of the reintroduced population. This phenomenon might be explained by mtDNA-encoded mutations. Moreover, captive breeding and release history might contribute to an increase in the proportion of this haplotype in the wild. [ABSTRACT FROM AUTHOR]

Objectives: To understand the meaning of the experiences of breast cancer patients undergoing diagnostic and treatment processes. Material and methods: A descriptive qualitative study based on the hermeneutic-interpretative scientific paradigm and grounded in a phenomenological epistemological framework. The study included women aged 18 years or older diagnosed with breast cancer and treated at a university clinic in Bogotá, who were given a semi-structured interview. Procedure: Semi-structured interviews were conducted based on pre-established categories. Aspects evaluated: Knowledge about current breast cancer screening and detection patterns, current utilization patterns of healthcare services, and perceived healthcare needs. Results: Regarding Current knowledge patterns on breast cancer screening and detection, patients demonstrated limited awareness. Concerning Current utilization patterns of healthcare services, there were noted dissatisfactions with the administrative process. Regarding Perceived healthcare needs, a feeling of abandonment was identified, stemming from a lack of continuity in the care process. Additionally, two emergent categories were identified: trust in the healthcare system and predisposition to feelings of guilt due to a lack of knowledge about the disease. Conclusions: A comprehensive care process is needed that addresses the real medical needs of patients, beyond administrative concerns, and is focused on the quality of the doctor-patient relationship across the entire multidisciplinary team. [ABSTRACT FROM AUTHOR]

Copyright of Ethnologie Française is the property of Presses Universitaires de France and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Oesophagectomy is currently the curative treatment for oesophageal cancer. The aim of this study is to know the results of minimally invasive oesophagectomy in the short and medium term in patients operated on for squamous cell carcinoma and adenocarcinoma of the oesophagus in our hospital. Material and Methods: 19 patients were collected from January 2020 to June 2021 and all of them were followed up for 20 months. Different variables related to the patient, tumour, surgery and postoperative period were collected. Data were stored and processed using R-Comander statistical software assuming an α-error of 0.05. Results: The median total hospital stay was 29 days. Six patients required readmission to resuscitation: two for septic shock secondary to grade III anastomotic leak, one for upper gastrointestinal haemorrhage and three for respiratory failure. At 90 days, 5.3% of the total number of patients were readmitted. There were no deaths in the three months following surgery. All patients had a survival of more than six months. Overall survival at six, 12 and 18 months was 100, 84 and 63%. Disease-free survival at three months was 84%, at six months 63% and at one year 58%. Discussion: The results obtained in our study coincide with those reported in the literature. Minimally invasive oesophagectomy is therefore an effective technique in the treatment of oesophageal cancer [ABSTRACT FROM AUTHOR]

Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introducción: La Enfermedad Cardio Vascular es considerada como principal causa de muerte en pacientes con enfermedad renal crónica (ERC) en estadío 5, en diálisis y después del trasplante renal (TR). No hay una estrategia óptima de detección cardiovascular pre-trasplante, y la mayoría de las pruebas están limitadas a la detección de enfermedad coronaria. El objetivo del estudio fue medir el impacto de la enfermedad cardíaca pre-trasplante en la supervivencia general y del injerto a 12 y 24 meses. Métodos: Con una cohorte retrospectiva de pacientes con TR entre los años 2009-2019, se registraron los antecedentes cardiovasculares, etiología de ERC, cirugías cardiacas, diagnósticos ecocardiográficos y bioquímicos pre-trasplante. Para desenlaces, tasa de filtrado glomerular de egreso, a los 12 y 24 meses, número - causas de fallecimiento y desenlaces cardiovasculares a los 12 y 24 meses. Se analizaron las variables mediante X2, prueba T y supervivencia de Kaplan-Meier. Resultados: Ingresaron al estudio 326 pacientes. El 7.7 % contaba con diagnóstico cardiovascular previo al protocolo de trasplante, 3.6% contaba con intervención cardíaca, 11.4% con FEVI

Foundation: prostate cancer is a common oncological condition in men. The study of treatments, effectiveness and survival is a necessity. Objective: to compare survival in ecuadorian patients with prostate cancer treated clinically with radiotherapy and chemotherapy in a hospital in the Amazon region. Method: an observational, analytical prospective cohort study was carried out in 74 patients with prostate cancer. The variables were analyzed: survival time, treatment, survival function, risk function. It was developed in two phases, in the first the average survival time of the patients was calculated, while in the second the comparison of survival between patients treated with radiotherapy and chemotherapy was carried out. The Chi-square test and the Log Rank (Mantel-Cox) statistic were used to evaluate significant differences in survival distributions between the groups. Results: the mean overall survival was 46.2 months; higher in the group that received radiotherapy (50.3 months) compared to the chemotherapy group (39.4 months). Greater cumulative survival was observed in patients who received radiotherapy. In the chemotherapy group, the cumulative risk curve tended to increase more steeply as the months passed compared to the radiotherapy group; however, no statistically significant difference in survival was identified between groups (p > 0 .05) Conclusions: greater survival was found in the group that received radiotherapy, however, no significant difference in survival was found between groups.

Este artículo espartede una tesis doctoral defendida en julio de 2023 y tiene como objetivo discutir formas de narrar y, simultáneamente, ocultar la historia haitiana, especialmente en lo que se refiere a las luchas de resistencia a la esclavitud vividas por las poblaciones negras en la parte occidental de la isla de Hispaniola, en el Caribe y el proceso de independencia de Haití a fines del siglo XVIII y principios del XIX. Estas luchas y la constitucióndel país caribeño cuestionaron la Ilustración francesa y los ideales revolucionarios (1789-1899) y, por ello, han sido silenciadas por la historiografía, además de la imposición de una serie de embargos que impidieron que Haití se convirtiera en un país efectivamente libre. Presentamos un enfoque que promueve el análisis de las narrativas producidas sobre Haití y sus habitantes, así como las prácticas de resistencia elaboradas por sujetos inscritos en estos procesos de diálogo, tensión y redireccionamiento de esas mismas narrativas, con el objetivo de transformarlas en instrumentos de supervivencia y lucha, como en los casos diásporas y la práctica del vudú. Se trata de un estudio basado en una revisión bibliográfica y documental sostenida por intelectuales como Protzel (2015), Haesbaert y Limonad (2007), Orlandi (2007) y Trouillot (2016); Édouard Glissant (2005) y James (2000). Los análisis indican que estas limitaciones (de los ideales ilustrados), sumadas a las prácticas de resistencia elaboradas por los subalternizados, operan como una interpelación al tiempo presente, exigiendo la inserción de los desplazados en el ámbito de los derechos, cuidados y protecciones prometidos por la modernidad que, contradictoriamente, se asentó sobre cuerpos racializados en territorios narrados como espacios de “salvajismo” y “barbarie”.

Characterizing natal dispersal can help manage the spread of invasive species expanding their ranges in response to land use and climate change. The Barred Owl (Strix varia) is a prominent example of an apex predator undergoing a rapid range expansion, having spread from eastern to western North America where it is now hyperabundant--threatening the Northern Spotted Owl (Strix occidentalis caurina) with extinction and potentially endangering many other native species. We attached satellite tags to 31 Barred Owl juveniles at the southern leading edge of the Barred Owl's expanding range in California to characterize natal dispersal patterns and inform management. Juveniles traveled up to 100 km from natal territories and experienced high mortality (annual survival = 0.204). At landscape scales, juveniles preferentially used forests, shrublands, and lower elevations during dispersal and avoided grasslands and burned areas. At finer scales, juveniles preferred shorter (younger) forests, lower elevations, and drainages, and avoided unforested areas. Our results suggest that the Barred Owl range expansion is being driven primarily by high reproductive rates and densities despite low juvenile survival rates and dispersal through putatively suboptimal younger forests as a result of exclusion from high-quality habitat by territorial individuals. These findings also point to several strategies for conserving Spotted Owls and other native species in the Barred Owl's expanded range, including: (1) creating and maintaining Barred Owl-free reserves bounded by open or high elevation areas, (2) creating reserves large enough to reduce immigration by long-distance dispersers, and (3) removing Barred Owls from large riparian corridors. [ABSTRACT FROM AUTHOR]

Timely detection and understanding of causes for population decline are essential for effective wildlife management and conservation. Assessing trends in population size has been the standard approach, but we propose that monitoring population health could prove more effective. We collated data from 7 bottlenose dolphin (Tursiops truncatus) populations in the southeastern United States to develop a method for estimating survival probability based on a suite of health measures identified by experts as indices for inflammatory, metabolic, pulmonary, and neuroendocrine systems. We used logistic regression to implement the veterinary expert system for outcome prediction (VESOP) within a Bayesian analysis framework. We fitted parameters with records from 5 of the sites that had a robust network of responders to marine mammal strandings and frequent photographic identification surveys that documented definitive survival outcomes. We also conducted capture–mark–recapture (CMR) analyses of photographic identification data to obtain separate estimates of population survival rates for comparison with VESOP survival estimates. The VESOP analyses showed that multiple measures of health, particularly markers of inflammation, were predictive of 1‐ and 2‐year individual survival. The highest mortality risk 1 year following health assessment related to low alkaline phosphatase (odds ratio [OR] = 10.2 [95% CI: 3.41–26.8]), whereas 2‐year mortality was most influenced by elevated globulin (OR = 9.60 [95% CI: 3.88–22.4]); both are markers of inflammation. The VESOP model predicted population‐level survival rates that correlated with estimated survival rates from CMR analyses for the same populations (1‐year Pearson's r = 0.99, p = 1.52 × 10–5; 2‐year r = 0.94, p = 0.001). Although our proposed approach will not detect acute mortality threats that are largely independent of animal health, such as harmful algal blooms, it can be used to detect chronic health conditions that increase mortality risk. Random sampling of the population is important and advancement in remote sampling methods could facilitate more random selection of subjects, obtainment of larger sample sizes, and extension of the approach to other wildlife species. [ABSTRACT FROM AUTHOR]

Bivariate failure data are common in reliability and survival studies, where estimation of dependency is often an important step in data analysis. In the literature, it known that the correlation coefficients measure the linear relationship between two variables, but strong non-linear relationship can also exist between them. Kendall's T concordance coefficient has become a useful tool for bivariate data analysis, which is used in nonparametric tests of independence and as a complementary measures of association. In the analysis of reliability data, there is a phenomenon that occurs when the value of the lifetime is partially known, which is known as censoring. In this paper, two estimation methods of Kendall's t are compared via simulation, one of them assuming normality in marginal distributions and adjusting them individually and the other based on copulas (Gaussian and Clayton), where the bivariate data are interval censored. The comparison is made using the mean squared error and the median absolute deviation. The results show that the method based on the copula approximation generally produces more precise estimates than the method of individual adjustment of the marginals. [ABSTRACT FROM AUTHOR]

The article presents Social Psychology of Work (SPW) as a perspective for studies and practices that involve the reality of workers in different forms of employment relationship. Based on workers' views of their own organizational processes in work routine, SPW positions itself in favor of their demands and assumes an ethical-political stance in defense of social justice. To exemplify the possibilities of the SPW, the article summarizes the results of two doctoral studies that focused on different situations in the Brazilian context: truck cargo porters working in the city of Sorocaba (São Paulo) and day laborer domestic cleaners working in the city of Fortaleza (Ceará). Both studies show that SPW is a fruitful way of both producing knowledge critical towards the mainstream mode of production and valuing the practical knowledge of workers who survive on the sidelines of labor regulations. [ABSTRACT FROM AUTHOR]

Introduction: Sleep is essential for human health, and it is influenced by internal circadian rhythms that can be adjusted by external cues such as light. The nematode Caenorhabditis elegans is an invertebrate model that shows similarities to mammalian-sleep patterns. However, excessive light exposure can negatively affect stress induced sleep (SIS). Objective: To evaluate the effect of blue light (LED) and medium wave UV (UVB) on the survival of C. elegans and compare with the circadian cycle of 12 h white light exposure. Methods: An experiment was carried out using L1 larvae of C. elegans N2 cultured on NGM agar with a food source of E. coli OP50, and subjected to darkness, white, LED and UVB Lights in periods of 12 h and 24 h. Results: At the end of the experiment, an increase in mortality due to phototoxicity was evident, demonstrated by a lower survival rate in the larvae exposed for 24 h, when compared to the larvae that remained in permanent darkness, a natural condition of the parasite. Conclusions: These results show us that the longer the exposure photoperiod, the shorter the survival of C. elegans. [ABSTRACT FROM AUTHOR]

The eccrine porocarcinoma (EPC) is a cancer of the sweat glands in the skin, with a diverse clinical presentation that includes plaques, ulcerated nodules, and polypoid lesions. Symptoms may involve itching, pain, and inflammation, in addition to signs of malignancy such as ulcers, bleeding, rapid growth, or pain. Histopathology shows the proliferation of atypical cells with malignant features, including pleomorphism and nuclear hyperchromasia. It can metastasize to distant organs, with common sites being bone, bladder, retroperitoneum, among others. Survival depends on the tumor size, with worse prognosis for tumors larger than 4 cm. The primary treatment is surgical removal, especially in early stages, with lymph node dissection in cases of involvement. Mohs micrographic surgery is used for localized cases. Radiation therapy and chemotherapy may be options in cases of metastasis or recurrence. Long-term follow-up is crucial, and ongoing research is needed to improve treatment strategies. [ABSTRACT FROM AUTHOR]

Background: Children with congenital heart disease present a higher frequency of cardiorespiratory arrest (CRA) than the general pediatric population. The epidemiology of CRA is not exactly known in our setting, nor are the mortality risk or the neurological evolution factors. Objective: To describe the epidemiology and outcomes associated with pediatric cardiopulmonary resuscitation in a cardiovascular recovery unit. The primary endpoint was the survival to discharge and the secondary endpoints were the return to spontaneous circulation, the survival at 24 hours and the remote neurological condition. Methods: Descriptive, prospective, longitudinal cohort study in children under 18 years of age who required cardiopulmonary resuscitation between 2016 and 2019. Demographic variables, characteristics of cardiopulmonary arrest, resuscitation and outcome were analyzed. An uni- and multivariate analysis was performed comparing survivors and deceased. Results: Out of 1,842 hospitalized patients, 4.1% presented CRA. Fifty patients with complete records were analyzed. Seventy-eight percent (39) returned to spontaneous circulation with a high survival rate of 46%. Resuscitation > 6 min and the use of vasoactive drugs were predictors of mortality; 16/23 patients were followed up, 10 of them with normal development for age at 6 months, six had pervasive developmental disorder. Conclusions: 4.1% of patients presented CRA, with a rate of 3.4 CRA per 1,000 patient-days. Survival at hospital discharge (n = 50) was 46%. Resuscitation > 6 min and the use of vasoactive drugs were independent predictors of mortality. At six months, 63% had normal neurological development for age. [ABSTRACT FROM AUTHOR]

Copyright of Colombian Journal of Nephrology / Revista Colombiana de Nefrología is the property of Colombian Association of Nephrology & Hypertension and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Tesla Revista Científica is the property of Puerto Madero Editorial Academica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pós: Revista do Programa de POS-Graduacao Em Artes - EBA/UFMG is the property of Pos - Programa de Pos-graduacao em Artes (PPG-Artes) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To evaluate conservation interventions, it is necessary to obtain reliable population trends for short (<10 years) time scales. Telemetry can be used to estimate short‐term survival rates and is a common tool for assessing population trends, but it has limitations and can be biased toward specific behavioral traits of tagged individuals. Encounter rates calculated from transects can be useful for assessing changes across multiple species, but they can have large confidence intervals and be affected by variations in survey conditions. The decline of African vultures has been well‐documented, but understanding of recent trends is lacking. To examine population trends, we used survival estimates from telemetry data collected over 6 years (primarily for white‐backed vultures [Gyps africanus]) and transect counts conducted over 8 years (for 7 scavenging raptors) in 3 large protected areas in Tanzania. Population trends were estimated using survival analysis combined with the Leslie Lefkovitch matrix model from the telemetry data and using Bayesian mixed effects generalized linear regression models from the transect data. Both methods showed significant declines for white‐backed vultures in Ruaha and Nyerere National Parks. Only telemetry estimates suggested significant declines in Katavi National Park. Encounter rates calculated from transects also showed declines in Nyerere National Park for lappet‐faced vultures (38% annual declines) and Bateleurs (18%) and in Ruaha National Park for white‐headed vultures (Trigonoceps occipitalis) (19%). Mortality rates recorded and inferred from telemetry suggested that poisoning is prevalent. However, only 6 mortalities of the 26 presumed mortalities were confirmed to be caused by poisoning, highlighting the challenges of determining the cause of death when working across large landscapes. Despite declines, our data provide evidence that southern Tanzania has higher current encounter rates of African vultures than elsewhere in East Africa. Preventing further declines will depend greatly on mitigating poisoning. Based on our results, we suggest that the use of multiple techniques improves understanding of population trends over the short term. [ABSTRACT FROM AUTHOR]

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introducción: el adenocarcinoma es el cáncer de pulmón de mayor incidencia, con tendencia a metastizar de forma amplia, con frecuencia en las glándulas suprarrenales donde solo alcanzan la curación una minoría de pacientes. Objetivo: presentar el caso de un paciente con adenocarcinoma de pulmón con metástasis suprarrenal bilateral. Presentación del caso: paciente masculino de 75 años, fumador inveterado, con diagnóstico de adenocarcinoma de pulmón en el que se detectó, tras estudios imagenológico de seguimiento, metástasis suprarrenal bilateral, se le realizó suprarrenalectomía con un año de diferencia entre ellas, recibió tratamiento con quimioterapia y terapéutica de mantenimiento con doblete de inmunoterapia. Conclusiones: lo más relevante resulta el hecho de poseer una supervivencia mayor a tres años y con buen estado general. Sin embargo, el promedio de supervivencia a nivel mundial es de veintiséis meses y tras la implementación de la inmunoterapia en asociación de quimioterapia se han recogido cifras más elevadas.

La creencia en la resurrección de los muertos es central para las religiones abrahámicas. Al estar actualmente desacreditada la noción de alma, muchos filósofos cristianos materialistas se replantean la posibilidad de tal resurrección. Dos problemas fundamentales amenazan tal posibilidad: la discontinuidad espacio-temporal entre la muerte y la resurrección (que impediría esta última si fuera imposible una existencia intermitente para los seres humanos) y la degeneración, disgregación o incluso completa destrucción de los componentes materiales del cuerpo (que impediría la reconstrucción del cuerpo original). Ambas cuestiones ponen en peligro la identidad numérica entre la persona muerta y la resucitada. Tras examinar diversas hipótesis recientes que intentan superar estas dificultades, constato que, o bien recurren a ideas disparatadas para asegurar la identidad, o asumen directamente que el cuerpo resucitado es una mera copia del original. Así, concluyo que, supuesta una concepción puramente corporalista de la persona, no parece viable ninguna noción de resurrección que preserve la identidad personal.

Fundamento: en las últimas seis décadas han existido avances significativos en la supervivencia de los pacientes y en los resultados funcionales tras una cirugía de reemplazo de válvulas cardíacas. Objetivo: identificar factores predictivos de supervivencia relacionados con el síndrome de bajo gasto cardíaco, en pacientes con cirugía cardíaca valvular, atendidos en el Centro de Cirugía Cardiovascular y Cardiología, Hospital Provincial Clínico Quirúrgico Docente Saturnino Lora Torres, en Santiago de Cuba, entre enero 2019 y diciembre 2021. Métodos: se realizó un estudio analítico de casos y controles en pacientes que tuvieron síndrome de bajo gasto cardíaco en el período posoperatorio, luego de recibir cirugía valvular cardíaca en el centro y período de tiempo antes declarados. Se trabajó con una muestra de 168 pacientes, divididos en dos grupos: uno con 56 casos de síndrome de bajo gasto cardíaco y 112 controles, que no presentaron esta entidad. Resultados: 34,5 % de los pacientes tenían edad ≥ 65 años; el antecedente de diabetes mellitus y de fibrilación auricular mostraron asociación con la aparición de bajo gasto cardíaco. La cirugía de emergencia (en 45,2 % de los pacientes); sangramiento, tiempo de circulación extracorpórea, función sistólica del ventrículo izquierdo y excursión sistólica del plano anular tricúspideo alterados, además de la presencia de hipertensión pulmonar, evidenciaron asociación. Conclusiones: la edad > 65 años, disfunción de ambos ventrículos deprimida, el antecedente de fibrilación auricular y el tiempo de circulación extracorpórea mayor de 90 minutos, son capaces de predecir la aparición de bajo gasto cardíaco y la supervivencia.

Introducción: la vasculitis asociada a anticuerpo anti-citoplasma de neutrófilo (ANCA) afecta los vasos de pequeño tamaño. Existen pocos reportes en pacientes hospitalizados. El objetivo del estudio fue describir las características demográficas, clínico-patológicas, complicaciones, recaídas y desenlaces. Propósito: describir la experiencia en el diagnóstico, manejo y desenlaces de esta patología durante 6 años. Materiales y métodos: estudio descriptivo retrospectivo de corte transversal. Muestreo no probabilístico por conveniencia desarrollado en el Hospital Universitario Clínica San Rafael Bogotá, Colombia, entre 2017-2022. Resultados: se incluyeron 23 pacientes. El 60,9 % hombres con edad media de 50 años. El principal síntoma fue hemoptisis (21,7 %). El 47,6 % se comportó como una glomerulonefritis rápidamente progresiva, y el 21,7 % presentó compromiso pulmonar. La positividad de pANCAS, cANCAS, ANAS, anti-MPO y anti-PR3 fue del 73,9 %, 13 %, 47,6 %, 31,6 % y 8,3 %, respectivamente. Se realizó biopsia en 21 pacientes con un promedio de 22 glomérulos, documentando 70 % de patrón pauciinmune. Se hizo recambio plasmático en el 73,9 % y el esquema más utilizado fue el CYCLOPS (78,3 %). Ningún paciente falleció. El 73,9 % requirió diálisis, de los cuales el 60,9 % egresó en diálisis. Se observó una recuperación de la función renal entre 6 y 12 meses en 21,7 % y 26,1 %. La recaída al año se presentó en el 27,3 %. Conclusión: Es fundamental conocer las manifestaciones clínicas, las pruebas diagnósticas y el tratamiento de esta entidad, en especial, porque si se realiza de manera eficaz, se pueden modificar la mortalidad y las complicaciones. Los pacientes que recibieron un tratamiento oportuno presentaron un elevado porcentaje de recuperación renal a pesar del severo compromiso en la biopsia renal.

Introduction: Heart surgical intervention is complex, but with satisfactory results for the patient, because it increases his survival and life quality. The low cardiac output syndrome in the postoperative period is one of the entities that darkens the prognosis of this operation and elevates the morbidity and mortality indexes in these patients. Objective: To estimate the survival of patients with low cardiac output syndrome in the postoperative period according to clinical and echocardiographyc variables. Methods: A cohort investigation of survival in 56 operated patients was carried out, who were diagnosed with postoperative low cardiac output syndrome and were assisted in the Cardiology and Cardiovascular Surgery Center of Santiago de Cuba, from January, 2019 to November, 2021. Results: There was prevalence of the 65 years and over age group (60.7%), the diabetes mellitus (44.6%) as personal pathological history and patients with ejection fraction of 45% or more who presented higher quantity of deaths (29.8%). The function of the affected right ventricle was found in 52.6% of deaths. The time of extracorporeal circulation of 90 minutes or more prevailed in 67.9% of those affected, of whom 42.1% died. Conclusions: It was observed that diabetes mellitus, the time of extracorporeal circulation and the long perioperative bleeding, as well as the biventricular systolic function was related to the prognosis of low cardiac output syndrome in the postoperative period.

Introducción: La inmunoterapia con pembrolizumab ha mejorado el pronóstico del cáncer de pulmón metastásico. En el presente caso se presenta la supervivencia extendidad y evolución de un paciente específico. Caso clínico: Hombre de 66 años, fumador. Diagnosticado de masa pulmonar en lóbulo inferior izquierdo de dimensiones 9 x 8 cm, con metástasis supra e infratentoriales intraaxiliares. Taller diagnóstico: Establecida como neoplasia de pulmón en estadio IVc, se comprobó el estado de PDL1 que positivo en un 80 % de la muestra de masa pulmonar. Debuta con infecciones infecciones pulmonares asociadas con un bacilo gramnegativo Hafnia alvei. Evolución: Se inció cefalosporinas y tratamiento inmunoterapia con Pembrolizumab, el cual se mantubo por 33 meses hasta la presencia de un efcto secundario atribuido al pembrolizumab, cumpliendo 35 meses de supervivencia hasta el cierre de esta observación no se reportó la muerte del paciente. Conclusiones: En el presente reporte, la determinación del biomarcador histológico PDL1 positivo en cáncer de pulmón ayudo a prescribir un tratamiento con inmunoterpia dirigida, lo que demostró aumentar la supervivencia más allá que el tratamiento convencional con quimioterapia. En el presente caso el tratamiento oportuno de infecciones bacterianas pulmonares conjuntamente con el estudio de tubercolosis también contribuyo a la supervivencia prolongada.

Introducción: El objetivo del presente estudio fue evaluar las características clínicas, patológicas e histológicas tumorales y su asociación con la recurrencia, metástasis y pronóstico en términos de supervivencia global y libre de enfermedad, de las pacientes que padecen sobrepeso u obesidad al momento del diagnóstico de cáncer de mama. Materiales y métodos: Se condujo un estudio descriptivo, longitudinal, retrospectivo, en un centro oncológico de referencia de Medellín. Se recolectó información de pacientes mayores de 18 años, con cáncer de mama infiltrante temprano y avanzado, entre los años 2012 – 2017, quienes presentaran IMC > 25 kg/m 2 al momento del diagnóstico. Las medianas de supervivencia se calcularon a través de curvas de Kaplan Meier y las diferencias mediante Log Rank Test. Resultados: Se analizó información de 1.349 pacientes. La mortalidad por todas las causas fue de 13.6% y aumentó proporcionalmente con el IMC (HR = 1.03, IC 1.0-1.05). Se identificaron 12.6% de recurrencias y el riesgo con el aumento de IMC no fue estadísticamente significativo (HR =1.02, IC 0.99 - 1.05). Características como mala diferenciación tumoral, invasión linfovascular y estadio tumoral se asociaron de forma univariada con mayor mortalidad. Conclusión: Se demostró una asociación positiva e independiente entre el IMC elevado, la mortalidad y el riesgo de recurrencia en pacientes con cáncer de mama. Así como una asociación con fenotipos tumorales agresivos y características de peor pronóstico. Se sugiere considerar modificaciones en el estilo de vida y un manejo multidisciplinario, como estrategias que posiblemente impacten en estos desenlaces.

The demography of, and factors that influence these metrics, are largely unknown for most vultures in the Americas. Survivorship of Turkey Vultures (Cathartes aura) may be influenced by landscape heterogeneity and human disturbance. We quantified the effects of landscape composition (Shannon's diversity index) and configuration (contagion, edge density, and largest patch index), and human disturbance (road density) on the annual and seasonal survival probabilities of the three North American breeding populations (western, central, and eastern) of Turkey Vultures that spend the nonbreeding season in the southeastern portion of the Nearctic and the northern Neotropics during a 17-year period. We used Cox's proportional hazards models with time-varying covariates to estimate spatial and temporal changes in survival rates of adult Turkey Vultures. Road density, but not landscape composition or configuration, influenced survival rates in space and time. Overall annual survival averaged 0.87 (95% confidence interval [CI]: 0.74-0.98). Mortality risk was low in western and central populations (hazard ratio < 1) but was 3.7 times greater for vultures in the eastern population. Survival during the breeding (0.97, 95% CI: 0.96-0.98) and outbound migration (1.0, 95% CI: 1-1) seasons was significantly higher than the other seasons. Average survival tended to be higher for nonbreeding (0.81, 95% CI: 0.71-0.88) compared to return migration (0.69, 95% CI: 0.56-0.81) seasons. The risk of mortality for all vulture populations increased with road density, and this was greater during the nonbreeding and return migration seasons. The spatial variation in road density across the Americas may generate a network of ecological traps for Turkey Vultures induced to stop in areas of greater road-kill abundance. Road-killed animals acting as an attractant for vultures can increase the occurrence of vulture-vehicle collisions and potentially aggravate human-wildlife conflicts. Further analyses are needed to address survivorship and mortality factors for young birds. Our results may help the implementation of specific mitigation efforts to reduce human-vulture conflicts and vulture mortality. For instance, concentrating efforts to remove road-killed animals in areas where road density is highest can likely reduce vulture-vehicle collisions and associated mortalities of these birds. [ABSTRACT FROM AUTHOR]

Introduction: Heart surgical intervention is complex, but with satisfactory results for the patient, because it increases his survival and life quality. The low cardiac output syndrome in the postoperative period is one of the entities that darkens the prognosis of this operation and elevates the morbidity and mortality indexes in these patients. Objective: To estimate the survival of patients with low cardiac output syndrome in the postoperative period according to clinical and echocardiographyc variables. Methods: A cohort investigation of survival in 56 operated patients was carried out, who were diagnosed with postoperative low cardiac output syndrome and were assisted in the Cardiology and Cardiovascular Surgery Center of Santiago de Cuba, from January, 2019 to November, 2021. Results: There was prevalence of the 65 years and over age group (60.7%), the diabetes mellitus (44.6%) as personal pathological history and patients with ejection fraction of 45% or more who presented higher quantity of deaths (29.8%). The function of the affected right ventricle was found in 52.6% of deaths. The time of extracorporeal circulation of 90 minutes or more prevailed in 67.9% of those affected, of whom 42.1% died. Conclusions: It was observed that diabetes mellitus, the time of extracorporeal circulation and the long perioperative bleeding, as well as the biventricular systolic function was related to the prognosis of low cardiac output syndrome in the postoperative period. [ABSTRACT FROM AUTHOR]

Invasive Burmese pythons (Python bivittatus) in the Everglades of Florida, United States, have drastically reduced populations of mammals, yet populations of some rodents appear unaffected by the invasion. To understand this pattern, we radio-tagged cotton rats (Sigmodon hispidus) in areas of high and low python occurrence densities (hereafter occurrence) and quantified the effects of python occurrence, seasonality, and sex on their survival and cause-specific mortality. Cotton rat survival was not influenced by difference in python occurrence (hazard ratio = 1.32, 95% CI = 0.77–2.26, P = 0.30). However, cotton rats were at greater risk from mortalities caused by mammals in areas of low python occurrence. In areas with elevated python occurrence, we attributed most cotton rat mortalities to birds of prey (48.6%) and reptiles (non-python = 24.3%, python = 16.2%). Where python occurrence was relatively low, we attributed cotton rat mortalities to native reptilian (28.6%), avian (35.7%), and mammalian predators (35.7%) with no python-related deaths. In total, pythons were responsible for 11.8% of all cotton rat mortalities. Finding no difference in the survival of cotton rats, despite differences in the causative agents of mortality, suggests that predation pressure from an invasive predator was compensatory for cotton rat population dynamics. This type of compensatory mortality is common for small mammals and helps explain why mammal communities in python-invaded portions of the Greater Everglades Ecosystem are increasingly dominated by cotton rats and other rodents. [ABSTRACT FROM AUTHOR]

Objective: We aimed to describe the main demographic, clinical, laboratory and therapeutic characteristics and to identify whether they are associated with mortality in tracheostomized patients. Material and methods. Retrospective cohort study in adult patients diagnosed with COVID-19, admitted to ICU (Intensive Care Unit) and requiring tracheostomy. Demographic, clinical, laboratory and treatment data were obtained from the medical records of patients admitted to Hospital III Daniel Alcides Carrión in Tacna. The Cox proportional hazards model was used for survival analysis and hazard ratios (HR) with their 95% confidence intervals (95%CI) were calculated. Results. We evaluated 73 patients, 72.6% were men, the most common comorbidities were obesity (68.5%), type 2 diabetes mellitus (35.6%), and arterial hypertension (34.2%). Thirty-seven percent of the participants died during their stay at the ICU. The median time from intubation to tracheostomy and the duration of tracheostomy was 17 (RIC: 15- 21) and 21 (RIC: 3-39) days, respectively. Multivariate analysis showed that the factors associated with mortality were procalcitonin > 0.50 ng/dL at the time of tracheostomy (HRa: 2.40 95%CI: 1.03-5.59) and a PaO2/FiO2 ratio less than or equal to 150 mmHg (HRa: 4.44 95%CI: 1.56-12.60). Conclusions. The factors associated with mortality at the time of tracheostomy were procalcitonin > 0.50 ng/dL and a PaO2/FiO2 ratio less than or equal to 150 mmHg. [ABSTRACT FROM AUTHOR]

Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)