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33 results on '"Sabatino, Lorenzo"'

15. Topical Ectoine: A Promising Molecule in the Upper Airways Inflammation—A Systematic Review

Author

Casale, Manuele, Moffa, Antonio, Carbone, Samanta, Fraccaroli, Francesca, Costantino, Andrea, Sabatino, Lorenzo, Lopez, Michele Antonio, Baptista, Peter, Cassano, Michele, and Rinaldi, Vittorio

Subjects
Article Subject
Abstract

To date, topical therapies guarantee a better delivery of high concentrations of pharmacologic agents to the mucosa of the upper airways (UA). Recently, topical administration of ectoine has just been recognized as adjuvant treatment in the Allergic Rhinitis (AR) and Rhinosinusitis (ARS). The aim of this work is to review the published literature regarding all the potential therapeutic effects of ectoine in the acute and chronic inflammatory diseases of UA. Pertinent studies published without temporal limitation were selected searching on MEDLINE the following terms: “ectoine” and “nasal spray,” “oral spray,” “upper respiratory tract infections,” “rhinosinusitis,” “rhinitis,” “rhinoconjunctivitis,” “pharyngitis,” and “laryngitis.” At the end of our selection process, six relevant publications were included: two studies about the effect of ectoine on AR, one study about ARS, one study about rhinitis sicca anterior, and two studies about acute pharyngitis and/or laryngitis. Due to its moisturizing and anti-inflammatory properties, topical administration of ectoine could play a potential additional role in treatment of acute and chronic inflammatory diseases of UA, in particular in the management of sinonasal conditions improving symptoms and endoscopic findings. However, these results should be viewed cautiously as they are based on a limited number of studies; some of them were probably underpowered because of their small patient samples.

Published
2019
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17. Nasal Delivery Devices: A Comparative Study on Cadaver Model

Author

Moffa, Antonio, primary, Costantino, Andrea, additional, Rinaldi, Vittorio, additional, Sabatino, Lorenzo, additional, Trecca, Eleonora Maria Consiglia, additional, Baptista, Peter, additional, Campisi, Paolo, additional, Cassano, Michele, additional, and Casale, Manuele, additional

Published
2019
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19. Could Music Minimize Discomfort and Pain During Office-Based ENT Surgery?

Author

Casale, Manuele, primary, Sabatino, Lorenzo, additional, Moffa, Antonio, additional, Oliveto, Giuseppe, additional, Rinaldi, Vittorio, additional, Costantino, Andrea, additional, Vella, Paola, additional, Ianni, Andrea, additional, Petitti, Tommasangelo, additional, Baptista, Peter, additional, and Salvinelli, Fabrizio, additional

Published
2018
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20. Mobile applications in otolaryngology for patients: An update

Author

Casale, Manuele, primary, Costantino, Andrea, additional, Rinaldi, Vittorio, additional, Forte, Antonio, additional, Grimaldi, Marta, additional, Sabatino, Lorenzo, additional, Oliveto, Giuseppe, additional, Aloise, Fabio, additional, Pontari, Domenico, additional, and Salvinelli, Fabrizio, additional

Published
2018
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25. POST-TRAUMATIC DIPLOPIA

Author

Greco, Federico, primary, Mallio, Carlo Augusto, additional, Sabatino, Lorenzo, additional, Errante, Yuri, additional, Casale, Manuele, additional, Quattrocchi, Carlo Cosimo, additional, and Beomonte Zobel, Bruno, additional

Published
2016
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28. Hyaluronic acid: Perspectives in dentistry. A systematic review

Author

Casale, Manuele, primary, Moffa, Antonio, additional, Vella, Paola, additional, Sabatino, Lorenzo, additional, Capuano, Francesco, additional, Salvinelli, Beatrice, additional, Lopez, Michele Antonio, additional, Carinci, Francesco, additional, and Salvinelli, Fabrizio, additional

Published
2016
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30. Neck fat volume as a potential indicator of difficult intubation: A pilot study.

Author

Del Buono, Romualdo, Sabatino, Lorenzo, and Greco, Federico

Subjects
*LARYNGOSCOPY, *NECK anatomy, *FAT cells, *INTUBATION, *ANESTHESIOLOGY, *RETROSPECTIVE studies
Abstract

Background: Direct laryngoscopy is the gold standard of the airway management in patients without predicted difficulties. If unpredicted difficulties are encountered instead, different algorithms to follow have been developed. To date, no single predictor is sufficiently valid. In clinical practice, it is used a combination of them to enhance the estimate, and despite the variety of parameters used, not all the difficult intubations are predicted. The aim of this work is to retrospectively analyze neck computed tomography scans of 37 patients who have had tracheal intubation and search for anatomic neck fat compartments that correlate with the intubation difficulty, and eventually find a suitable, clinical parameter that can potentially enhance the prediction of a difficult airway when used in combination of the preexisting scores. Materials and Methods: the patients are divided by direct laryngoscopy view into two groups: Group A (n = 31): Normal airway, with a Cormack Lehane, Score I or II; Group B (n = 6): Difficult airway, with a Cormack Lehane Score III or IV. In the zone of interest, it was measured the neck volume parameter and other subparameters. Results: Despite a positive trend is shown for anterior fat volume (AFV) (P = 0.23) and fat volume (FV) (P = 0.28), statistically significant differences (P < 0.05) were not found between Group A and B in any of the measurements acquired. Conclusions: According to the literature, our results confirmed that there is still no single element that can predict a difficult intubation. Although no statistical significance was found, the AFV and FV have shown to have a potential predictive role for difficult intubation. Further studies with bigger samples are advisable to confirm this encouraging result. [ABSTRACT FROM AUTHOR]

Published
2018
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