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1. Contents Vol. 25, 2008

Author

Camilla Brandt, Lars-Olof Wahlund, Tomoko Okina, Gunhild Waldemar, Dionísio Azevedo, Ellen Gelpi, Rémi W. Bouchard, O. Fontaine, P. Missotten, Yasuhiro Nagahama, Sabine Torma, Serge Gauthier, Minoru Matsuda, Nils-Olof Hagnelius, Karl Heinz Tragl, Torbjörn K. Nilsson, Justyna C. Bahl, F.U.S. Mattace-Raso, Elisabet Londos, David B. Hogan, Ging-Yuek Robin Hsiung, Claudia Jacova, Oskar Hansson, Peder Buchhave, Peter Bauer, Selma Hoenigschnabl, Sabine Nore, Mariana Tatsch, D. Di Notte, T.J.M. van der Cammen, Sina Alipour, Kenneth Rockwood, Ragnhild Skogseth, Wolfgang Krampla, Silvia Weissgram, E.M. Colin, Kaj Blennow, Erik Stomrud, Margarete Hinterberger, Sonja Zehetmayer, Norio Suzuki, Hans Förstl, Kurt Bauer, Klaus Huber, N. van der Velde, Sandra E. Black, Peter Johannsen, Siegbert Warkentin, Michael Rainer, Sergio R. Hototian, Peter Fischer, Cláudio C. Castro, Clive Ballard, Guido Alves, Niels H.H. Heegaard, Robert Perneczky, G. Squelard, Susanne Jungwirth, C. Oudshoorn, Jacob Grand, Arvid Rongve, L. Paquay, Dag Aarsland, Henning Boecker, Ezra Mulugeta, M. Ylieff, Howard Feldman, Peter Häussermann, Andrew Kertesz, Lars Gerhardsson, Mario C. Bazzarella, Alexander Drzezga, Alexander Kurz, Thomas Lundh, Inge Loy-English, J. De Lepeleire, Cássio M. C. Bottino, F. Buntinx, Thomas Leitha, and Lennart Minthon

Subjects
Psychiatry and Mental health, Cognitive Neuroscience, Geriatrics and Gerontology
Published
2008
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2. Risk Factors for Alzheimer Dementia in a Community-Based Birth Cohort at the Age of 75 Years

Author

Sabine Torma, Peter Bauer, Klaus Huber, Michael Rainer, Peter Fischer, Margarete Hinterberger, Karl Heinz Tragl, Kurt Bauer, Ellen Gelpi, Thomas Leitha, Wolfgang Krampla, Selma Hoenigschnabl, Susanne Jungwirth, Sonja Zehetmayer, and Silvia Weissgram

Subjects
Male, Proband, medicine.medical_specialty, Multivariate analysis, Cognitive Neuroscience, Cohort Studies, Alzheimer Disease, Residence Characteristics, Risk Factors, Internal medicine, medicine, Humans, Dementia, Prospective Studies, Risk factor, Prospective cohort study, Aged, business.industry, Cognitive disorder, medicine.disease, Surgery, Psychiatry and Mental health, Logistic Models, Austria, Multivariate Analysis, Female, Geriatrics and Gerontology, Alzheimer's disease, business, Follow-Up Studies, Cohort study
Abstract

Background: Few prospective community-based cohort studies have so far concentrated specifically on the risk factors for Alzheimer dementia (AD) with onset after the age of 75 years. Methods: We prospectively investigated a birth cohort of 585 nondemented inhabitants in the area on the East bank of the river Danube who were born between 1925 and 1926. They were investigated at the age of 75 years and followed up after 30 months. The follow-up was possible with 488 probands; 36 died, and 61 refused to participate. Results: In multivariate analysis an elevated risk for late-onset AD could be found for (1) history of depressive episodes (OR = 2.09; 95% CI = 1.25–3.48); (2) the Ε4 allele of the APOE gene (OR = 1.86; 95% CI = 1.08–3.23); (3) lower serum level of folate (OR = 0.92; 95% CI = 0.87–0.98); (4) no chronic use of nonsteroidal anti-inflammatory drugs (OR = 0.40; 95% CI = 0.20–0.81), and (5) lower education (OR = 1.43; 95% CI = 1.03–2.00). Conclusions: Five risk factors for late-onset AD could be confirmed, which might be targets for preventive strategies.

Published
2008
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3. Subject Index Vol. 25, 2008

Author

L. Paquay, Oskar Hansson, Thomas Leitha, Lennart Minthon, Sabine Nore, Camilla Brandt, Lars Gerhardsson, Mario C. Bazzarella, Alexander Drzezga, Thomas Lundh, Margarete Hinterberger, Torbjörn K. Nilsson, Ezra Mulugeta, M. Ylieff, Sina Alipour, O. Fontaine, Sabine Torma, Karl Heinz Tragl, Selma Hoenigschnabl, Mariana Tatsch, E.M. Colin, Serge Gauthier, Inge Loy-English, Kurt Bauer, Sonja Zehetmayer, Arvid Rongve, Peter Johannsen, J. De Lepeleire, Siegbert Warkentin, Dionísio Azevedo, Silvia Weissgram, Justyna C. Bahl, T.J.M. van der Cammen, Ellen Gelpi, Peter Häussermann, Wolfgang Krampla, N. van der Velde, Sandra E. Black, Tomoko Okina, Norio Suzuki, Peter Bauer, Minoru Matsuda, Sergio R. Hototian, Susanne Jungwirth, Lars-Olof Wahlund, Elisabet Londos, Niels H.H. Heegaard, F. Buntinx, Robert Perneczky, C. Oudshoorn, Claudia Jacova, Henning Boecker, Hans Förstl, Peder Buchhave, Cássio M. C. Bottino, P. Missotten, G. Squelard, Ging-Yuek Robin Hsiung, Yasuhiro Nagahama, Peter Fischer, Howard Feldman, Nils-Olof Hagnelius, Ragnhild Skogseth, Klaus Huber, Michael Rainer, Kaj Blennow, Dag Aarsland, Kenneth Rockwood, F.U.S. Mattace-Raso, Erik Stomrud, Andrew Kertesz, Cláudio C. Castro, Clive Ballard, Guido Alves, Jacob Grand, Gunhild Waldemar, D. Di Notte, Rémi W. Bouchard, David B. Hogan, and Alexander Kurz

Subjects
Psychiatry and Mental health, Index (economics), Cognitive Neuroscience, Subject (documents), Geriatrics and Gerontology, Psychology, Developmental psychology
Published
2008
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