46 results on '"Saffran, Holly A."'
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2. Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies
3. SARS-COV-2 recombinant Receptor-Binding-Domain (RBD) induces neutralizing antibodies against variant strains of SARS-CoV-2 and SARS-CoV-1
4. The Effect of Deuteration and Homologation of the Lactam Ring of Nirmatrelvir on Its Biochemical Properties and Oxidative Metabolism
5. Author Correction: Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
6. Interferon regulatory factor 3 mediates effective antiviral responses to human coronavirus 229E and OC43 infection
7. Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
8. Integrating Reverse Transcription Recombinase Polymerase Amplification with CRISPR Technology for the One-Tube Assay of RNA
9. Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability
10. Detection of SARS-CoV-2 using isothermal amplification and CRISPR technology
11. SARS-COV-2 Recombinant Receptor-Binding-Domain (RBD) Induces Neutralising Antibodies Against Variant Strains of SARS-CoV-2 and SARS-CoV-1
12. Peptidomimetic nitrile warheads as SARS-CoV-2 3CL protease inhibitors
13. Antibodies to neutralising epitopes synergistically block the interaction of the receptor‐binding domain of SARS‐CoV‐2 to ACE 2
14. Isothermal Amplification and Ambient Visualization in a Single Tube for the Detection of SARS-CoV-2 Using Loop-Mediated Amplification and CRISPR Technology
15. Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability.
16. Structural insights into the feline coronavirus drug GC376, which inhibits the main protease of SARS-CoV-2 and blocks virus replication
17. Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
18. The herpes simplex virus host shutoff (vhs) RNase limits accumulation of double stranded RNA in infected cells: Evidence for accelerated decay of duplex RNA
19. Herpes Simplex Virus vhs Protein
20. Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in VitroBiological Stability
21. Expression of the Vaccinia Virus Antiapoptotic F1 Protein Is Blocked by Protein Kinase R in the Absence of the Viral E3 Protein
22. Peptidomimetic nitrile warheads as SARS-CoV-2 3CL protease inhibitorsElectronic supplementary information (ESI) available. See DOI: 10.1039/d1md00247c
23. Role of Herpes simplex virus 1 VP11/12 tyrosine-based binding motifs for Src family kinases, p85, Grb2 and Shc in activation of the phosphoinositide 3-kinase-Akt pathway
24. The Herpes Simplex Virus Virion Host Shutoff Protein Enhances Translation of Viral True Late mRNAs Independently of Suppressing Protein Kinase R and Stress Granule Formation
25. The Herpes Simplex Virus 1 Virion Host Shutoff Protein Enhances Translation of Viral Late mRNAs by Preventing mRNA Overload
26. Regulation of human parainfluenza virus type 3 transcription
27. Herpes Simplex Virus Protein Kinases US3 and UL13 Modulate VP11/12 Phosphorylation, Virion Packaging, and Phosphatidylinositol 3-Kinase/Akt Signaling Activity
28. Elimination of Mitochondrial DNA Is Not Required for Herpes Simplex Virus 1 Replication
29. Role of Herpes Simplex Virus VP11/12 Tyrosine-Based Motifs in Binding and Activation of the Src Family Kinase Lck and Recruitment of p85, Grb2, and Shc
30. Evidence for Translational Regulation by the Herpes Simplex Virus Virion Host Shutoff Protein
31. Herpes Simplex Virus UL12.5 Targets Mitochondria through a Mitochondrial Localization Sequence Proximal to the N Terminus
32. Herpes simplex virus eliminates host mitochondrial DNA
33. Herpes Simplex Virus Infection Stabilizes Cellular IEX-1 mRNA
34. RNA Degradation Induced by the Herpes Simplex Virus vhs Protein Proceeds 5′ to 3′ In Vitro
35. Herpes Simplex Virus Virion Host Shutoff Protein Is Stimulated by Translation Initiation Factors eIF4B and eIF4H
36. Synthesis and Antiviral Activity of Novel Acyclic Nucleoside Analogues of 5-(1-Azido-2-haloethyl)uracils
37. Synthesis and Antiviral Activity of Novel 5-(1-Cyanamido-2-haloethyl) and 5-(1-Hydroxy(or methoxy)-2-azidoethyl) Analogues of Uracil Nucleosides
38. Herpes Simplex Virus Virion Host Shutoff Protein Requires a Mammalian Factor for Efficient In Vitro Endoribonuclease Activity
39. The vhs1 Mutant Form of Herpes Simplex Virus Virion Host Shutoff Protein Retains Significant Internal Ribosome Entry Site-Directed RNA Cleavage Activity
40. Herpes Simplex Virus ICP0 Mutants Are Hypersensitive to Interferon
41. Herpes simplex virus eliminates host mitochondrial DNA.
42. Herpes Simplex Virus Infection Stabilizes Cellular IEX-1 mRNA.
43. Evaluation of 5-[1-(2-Halo(or nitro)ethoxy-2-iodoethyl)]-2.... -deoxyuridines as Inhibitors of Herpes Simplex Virus.
44. The XIAP IRES activates 3' cistron expression by inducing production of monocistronic mRNA in the βgal/CAT bicistronic reporter system
45. Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability.
46. The XIAP IRES activates 3' cistron expression by inducing production of monocistronic mRNA in the betagal/CAT bicistronic reporter system.
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