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1. Fluorescence and FRET based mercury (II) sensor

Author

Saha, Dr. Jaba, Suklabaidya, Sudip, Nath, Dr. Jayasree, Roy, Dr. Arpan Datta, Dey, Bapi, Dey, Dr. Dibyendu, Bhattacharjee, Prof. D., and Hussain, Dr. Syed Arshad

Subjects
Condensed Matter - Materials Science
Abstract

A mercury (II) sensor has been proposed based on Fluorescence Resonance Energy Transfer (FRET) between N,N'-dioctadecyl thiacyanine perchlorate (NK) and Octadecyl rhodamine B chloride (RhB). Out of these two molecules NK is sensitive to Hg2+ ions due to presence of sulfur atom in it. Accordingly, presence of Hg2+ ions affects the NK fluorescence as well as FRET from NK to RhB. Our results showed that NK fluorescence intensity and FRET efficiency linearly decreases with increase in Hg2+ ion concentration. With proper optimization present system under investigations can be used to sense Hg2+ ions in aqueous solution with detection limit of 9.13 ppb. Advantage of this present system is that it is very simple compared to the other FRET based system and also it works under aqueous environment. This method has also been tested using real lake water and satisfactory results were obtained., Comment: 45 pages, 5 figures

Published
2019
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10. e-ConSus 2020

Author

Basu, Dr. Amitava, primary, Das, Dr. Sudipta, additional, Das, Mr. Rajarshi, additional, Maji, Mr. Kajal, additional, Shaw, Mr. Shashi Kr., additional, Saha, Dr. Nimai Chand, additional, Paria, Dr. Sayantan, additional, Adhikari, Dr. Aniruddha, additional, and Tribedi, Dr. Amit, additional

Published
2021
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17. Comparison of Outcome between Ostomy Closure with Permanent Synthetic Mesh and Conventional Technique without Mesh to Prevent Incisional Hernia

Author

Barai, Dr. Shyamal Chandra, primary, Sheikh, Md. Shahadot Hossain, additional, Taher, Dr. Abu, additional, Paul, Dr. Zhuma Rani, additional, Hyder, Dr. Chowdhury Sazzad, additional, Saha, Dr. Krishna Pada, additional, Or-Rashid, Dr. Mohammad Haroon, additional, Alam, Dr. Ishtiaq, additional, Pal, Dr. Arun Kumar, additional, and Uddin, Dr. Mohammad Azim, additional

Published
2023
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38. A COMPARATIVE OBSERVATIONAL STUDY OF PROGNOSTIC FACTOR SCORES TO PREDICT MORBIDITY AND MORTALITY IN PATIENTS OF PERFORATED PEPTIC ULCER

Author

Ananay Vishvakarma Dr, Anil Kumar Saha Dr, and Subhasish Roychowdhury Dr

Subjects
medicine.medical_specialty, Prognostic factor, business.industry, Internal medicine, Peptic ulcer, medicine, Observational study, In patient, medicine.disease, business
Abstract

Background: Perforation is one of the common complication of peptic ulcer disease which is associated with signicant morbidity and mortality. It is a disease which needs emergent surgical intervention. Accurate and early identication of high-risk patients with Perforated Peptic Ulcer is important for risk stratication. Here, we calculate the three prognostic factor scores, (i) The Boey Score, (ii) The Peptic ulcer perforation (PULP) score, and (iii) The quick sequential organ failure assessment (q-SOFA) score, preoperatively to predict postoperative outcome. Aims & Objective: The aim of the study is to identify patients with an increased risk of adverse outcome, so that we can target the level of perioperative monitoring and treatment in high-risk patients. Also, to determine and compare the ability of three prognostic factor scores to predict morbidity and mortality in patients of Perforated Peptic Ulcer. Methods: Aprospective comparative observational study was conducted comprising of 92 patients with conrmed perforated peptic ulcer (PPU) attending the emergency ward of Department of General Surgery between February 2019 to July 2020. After conrmation of diagnosis, risk stratication according to the three prognostic factor scores (Boey score, PULP score, and q-SOFA score) was done. Acomparison was made between each score through calculation of positive predictive value (PPV) and negative predictive value (NPV). We used receiver operating characteristics (ROC) curve in my study to estimate the predictive ability of each scoring system. Results: The study include 92 patients. Female 41.3% and Male 58.7%. The mean age was 45.38 years. The most common site of PPU was the rst part of duodenum - D1 (64.1%). The most common operative procedure done was the Grahm's patch repair. The morbidity rate was 28.3%. Overall mortality rate was 10.9%. The AUROC for morbidity prediction was 0.791 for Boey score, 0.918 for PULP score, and 0.61 for q-SOFAscore. The AUROC for mortality prediction was 0.829 for Boey score, 0.865 for PULPscore, and 0.602 for q-SOFAscore. Conclusion:Boey score and PULP score helps in accurate and early identication of PPU patients with an increased risk of adverse outcome. q-SOFA score cannot signicantly predict morbidity and mortality in PPU patients. Overall, PULP score performs best but Boey score is crude and simple to calculate and is used to assess the patient rapidly

Published
2021

42. Associations of Body Mass Index with Molecular Sub Types, Clinical and Pathological Characteristics of Breast Cancer in Bangladeshi Women

Author

Proteek, Dr. Mehdi Faruk, primary, Khatun, Prof. Dr. Nazrina, additional, Saha, Dr. Beauty, additional, Azim, Dr. Nazma, additional, Islam, Dr. Syed Md. Ariful, additional, Khurshid, Dr. Narita, additional, Bhuiyan,, Dr. Mohammad Rahmat Ullah, additional, Islam, Dr. Md. Rashedul, additional, Haque, Dr. Zakia, additional, Shahid, Dr. Tasnim Binta, additional, and Khan, Dr. Mohammad Kamruzzaman, additional

Published
2022
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46. Retinopathy of Prematurity –Recent Screening Status in a Tertiary Care Hospital of Bangladesh

Author

Rahman Dr. Maksudur, Chandra Saha Dr. Liton, Rahman Prof. Dr.Md. Mahbubur, and Kumar Nag Prof. Dr. Dipak

Subjects
Pediatrics, medicine.medical_specialty, business.industry, General Engineering, medicine, General Earth and Planetary Sciences, Retinopathy of prematurity, Tertiary care hospital, medicine.disease, business, Screening status, General Environmental Science
Abstract

Retinopathy of prematurity (ROP) results in severe visual impairment and blindness in newborns. In the recent days with development of the technology to save preterm infants, it’s incidence is increasing in both developed and developing countries. Only appropriate and timely screening program can prevent ROP and reduce the functional impairment of eyes. The aim of this study was to see the recent screening status of the hospital so that future plan of ROP treatment and prevention can be taken more appropriately. This prospective study was conducted from January 2018 to December 2018 in neonatology department of Dhaka Shishu (Children) Hospital. Neonates with gestational age < 34wks or birth weight

Published
2022

48. COLLAGEN DRESSINGS IN THE MANAGEMENT OF PAEDIATRIC FACIAL BURNS-OUR EXPERIENCE

Author

Sweta Sweta Dr, Debraj Saha Dr, and Anand Dugad Dr

Subjects
030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, business.industry, Medicine, 030208 emergency & critical care medicine, business
Abstract

Background-Facial Burns in the paediatric Populations are very common in our society. Facial burns in paediatric age group are usually caused due to accidental spillage and scalding by hot liquids. These burns are usually partial thickness in nature.Collagen dressing have a better outcome in the management of partial thickness facial burns. Wound healing is important with the aim to minimize the deformity and a cosmetically acceptable scar. Methodology- Thirty patients 3-12 years of age were included in a retrospective study from September 2017 to September 2018.All patients were analyzed in terms of age and sex, Type of burn, duration of presentation, degree and percentage of burns, complications, cosmetic outcome. Mean age of presentation 5.7yr. Ninety-six percent of childre Result- n had burns secondary to scalding. Dry collagen sheet applied to all 30 patients. Ninety-three percent patients had satisfactory healing in 10 days. Ninety percent patients experienced no pain with collagen in situ. Ten percent patients had minor complications where all patients were very comfortable with collagen dressing. Collagen dressing is very useful in rst and Conclusion- supercial second degree facial burns in paediatric populations. It is well tolerated, provides multiple benets, and it has fewer complications and excellent cosmetic outcome as our study showed.

Published
2021

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