1. Seroprevalence of hepatitis B and hepatitis C among blood donors in Sierra Leone: A multi-year retrospective study
- Author
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Francesca Tognon, Stephen Sevalie, Joseph Gassimu, John Sesay, Katrina Hann, Mohamed Sheku, Emily Bearse, Francesco Di Gennaro, Claudia Marotta, Giampietro Pellizzer, Giovanni Putoto, Marta Lado, Molly F. Franke, Yusupha Dibba, Sahr Gevao, Fenella Beynon, and Annelies W. Mesman
- Subjects
Viral hepatitis ,Sierra Leone ,Epidemiology ,Blood donors ,Seroprevalence ,Infectious and parasitic diseases ,RC109-216 - Abstract
Objectives: In Sierra Leone, very little data are available on hepatitis B virus (HBV) and hepatitis C virus (HCV) prevalence. Blood donor screening permits estimation of the prevalence of transfusion transmissible infections in a general open population. We analyzed blood donor data in Sierra Leone to estimate national viral hepatitis prevalence and identify risk factors for hepatitis infection among the donor population. Methods: We conducted a retrospective data analysis in five government hospitals. We collected HBV and HCV screening results, donor demographics, and donation type (family replacement or voluntary donor; first-time or repeat). Univariate and multivariate analyses were performed to determine associations between infections and socio-demographic factors. Results: The number of donors screened was 29,713. The overall prevalence was: 10.8% (3200) for HBV and 1.2% (357) for HCV. HBV infection was most strongly associated with male sex (p:
- Published
- 2020
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