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13. CEACAM6 Promotes Lung Metastasis via Enhancing Proliferation, Migration and Suppressing Apoptosis of Prostate Cancer Cells.

Author

SARAJI, ALIREZA, WULF, KATHARINA, STEGMANN-FREHSE, JANINE, DUAN KANG, OFFERMANN, ANNE, SHAGHOYAN, GEVORG, JONIGK, DANNY, KÜHNEL, MARK PHILIPP, PERNER, SVEN, KIRFEL, JUTTA, and SAILER, VERENA

Subjects
PROSTATE cancer, CELL adhesion molecules, CANCER cells, LUNGS, APOPTOSIS, GENE expression
Abstract

Background/Aim: Metastatic prostate cancer (mPCa) results in high morbidity and mortality. Visceral metastases in particular are associated with a shortened survival. Our aim was to unravel the molecular mechanisms that underly pulmonary spread in mPCa. Materials and Methods: We performed a comprehensive transcriptomic analysis of PCa lung metastases, followed by functional validation of candidate genes. Digital gene expression analysis utilizing the NanoString technology was performed on mRNA extracted from formalin-fixed, paraffin-embedded (FFPE) tissue from PCa lung metastases. The gene expression data from primary PCa and PCa lung metastases were compared, and several publicly available bioinformatic analysis tools were used to annotate and validate the data. Results: In PCa lung metastases, 234 genes were considerably up-regulated, and 78 genes were significantly down-regulated when compared to primary PCa. Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) was identified as suitable candidate gene for further functional validation. CEACAM6 as a cell adhesion molecule has been implicated in promoting metastatic disease in several solid tumors, such as colorectal or gastric cancer. We showed that siRNA knockdown of CEACAM6 in PC-3 and LNCaP cells resulted in decreased cell viability and migration as well as enhanced apoptosis. Comprehensive transcriptomic analyses identified several genes of interest that might promote metastatic spread to the lung. Conclusion: Functional validation revealed that CEACAM6 might play an important role in fostering metastatic spread to the lung of PCa patients via enhancing proliferation, migration and suppressing apoptosis in PC-3 and LNCaP cells. CEACAM6 might pose an attractive therapeutic target to prevent metastatic disease. [ABSTRACT FROM AUTHOR]

Published
2024
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16. FIGURE 1 from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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17. Supplementary Figure 1 from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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18. Supplementary Data Legends from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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19. Supplementary Table 1 from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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20. FIGURE 5 from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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21. FIGURE 3 from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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22. Supplementary Figure 3 from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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23. FIGURE 4 from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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24. Supplementary Figure 2 from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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25. FIGURE 2 from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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26. Data from The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, primary, Gayvert, Kaitlyn, primary, Branch, Jonathan R., primary, Brady, Nicholas J., primary, Basu, Subhasree, primary, Russell, Michael, primary, Cyrta, Joanna, primary, Vosoughi, Aram, primary, Sailer, Verena, primary, Alnajar, Hussein, primary, Dardenne, Etienne, primary, Koumis, Elena, primary, Puca, Loredana, primary, Robinson, Brian D., primary, Feldkamp, Michael D., primary, Winkis, Annmarie, primary, Majewski, Nathan, primary, Rupnow, Brent, primary, Gottardis, Marco M., primary, Elemento, Olivier, primary, Rubin, Mark A., primary, Beltran, Himisha, primary, and Rickman, David S., primary

Published
2023
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27. The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Author

Van Emmenis, Lucie, primary, Ku, Sheng-Yu, additional, Gayvert, Kaitlyn, additional, Branch, Jonathan R., additional, Brady, Nicholas J., additional, Basu, Subhasree, additional, Russell, Michael, additional, Cyrta, Joanna, additional, Vosoughi, Aram, additional, Sailer, Verena, additional, Alnajar, Hussein, additional, Dardenne, Etienne, additional, Koumis, Elena, additional, Puca, Loredana, additional, Robinson, Brian D., additional, Feldkamp, Michael D., additional, Winkis, Annmarie, additional, Majewski, Nathan, additional, Rupnow, Brent, additional, Gottardis, Marco M., additional, Elemento, Olivier, additional, Rubin, Mark A., additional, Beltran, Himisha, additional, and Rickman, David S., additional

Published
2023
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28. Metastatic Prostate Cancer

Author

Sailer, Verena, Cagle, Philip T., Series editor, Robinson, Brian D., editor, Mosquera, Juan Miguel, editor, Ro, Jae Y., editor, and Divatia, Mukul, editor

Published
2018
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29. Data from Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Author

Pauli, Chantal, primary, Hopkins, Benjamin D., primary, Prandi, Davide, primary, Shaw, Reid, primary, Fedrizzi, Tarcisio, primary, Sboner, Andrea, primary, Sailer, Verena, primary, Augello, Michael, primary, Puca, Loredana, primary, Rosati, Rachele, primary, McNary, Terra J., primary, Churakova, Yelena, primary, Cheung, Cynthia, primary, Triscott, Joanna, primary, Pisapia, David, primary, Rao, Rema, primary, Mosquera, Juan Miguel, primary, Robinson, Brian, primary, Faltas, Bishoy M., primary, Emerling, Brooke E., primary, Gadi, Vijayakrishna K., primary, Bernard, Brady, primary, Elemento, Olivier, primary, Beltran, Himisha, primary, Demichelis, Francesca, primary, Kemp, Christopher J., primary, Grandori, Carla, primary, Cantley, Lewis C., primary, and Rubin, Mark A., primary

Published
2023
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30. Supplementary Table 7 from Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Author

Pauli, Chantal, primary, Hopkins, Benjamin D., primary, Prandi, Davide, primary, Shaw, Reid, primary, Fedrizzi, Tarcisio, primary, Sboner, Andrea, primary, Sailer, Verena, primary, Augello, Michael, primary, Puca, Loredana, primary, Rosati, Rachele, primary, McNary, Terra J., primary, Churakova, Yelena, primary, Cheung, Cynthia, primary, Triscott, Joanna, primary, Pisapia, David, primary, Rao, Rema, primary, Mosquera, Juan Miguel, primary, Robinson, Brian, primary, Faltas, Bishoy M., primary, Emerling, Brooke E., primary, Gadi, Vijayakrishna K., primary, Bernard, Brady, primary, Elemento, Olivier, primary, Beltran, Himisha, primary, Demichelis, Francesca, primary, Kemp, Christopher J., primary, Grandori, Carla, primary, Cantley, Lewis C., primary, and Rubin, Mark A., primary

Published
2023
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31. Supplementary Figures 1 - 6 from Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Author

Pauli, Chantal, primary, Hopkins, Benjamin D., primary, Prandi, Davide, primary, Shaw, Reid, primary, Fedrizzi, Tarcisio, primary, Sboner, Andrea, primary, Sailer, Verena, primary, Augello, Michael, primary, Puca, Loredana, primary, Rosati, Rachele, primary, McNary, Terra J., primary, Churakova, Yelena, primary, Cheung, Cynthia, primary, Triscott, Joanna, primary, Pisapia, David, primary, Rao, Rema, primary, Mosquera, Juan Miguel, primary, Robinson, Brian, primary, Faltas, Bishoy M., primary, Emerling, Brooke E., primary, Gadi, Vijayakrishna K., primary, Bernard, Brady, primary, Elemento, Olivier, primary, Beltran, Himisha, primary, Demichelis, Francesca, primary, Kemp, Christopher J., primary, Grandori, Carla, primary, Cantley, Lewis C., primary, and Rubin, Mark A., primary

Published
2023
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32. Supplementary Table 1 from Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Author

Pauli, Chantal, primary, Hopkins, Benjamin D., primary, Prandi, Davide, primary, Shaw, Reid, primary, Fedrizzi, Tarcisio, primary, Sboner, Andrea, primary, Sailer, Verena, primary, Augello, Michael, primary, Puca, Loredana, primary, Rosati, Rachele, primary, McNary, Terra J., primary, Churakova, Yelena, primary, Cheung, Cynthia, primary, Triscott, Joanna, primary, Pisapia, David, primary, Rao, Rema, primary, Mosquera, Juan Miguel, primary, Robinson, Brian, primary, Faltas, Bishoy M., primary, Emerling, Brooke E., primary, Gadi, Vijayakrishna K., primary, Bernard, Brady, primary, Elemento, Olivier, primary, Beltran, Himisha, primary, Demichelis, Francesca, primary, Kemp, Christopher J., primary, Grandori, Carla, primary, Cantley, Lewis C., primary, and Rubin, Mark A., primary

Published
2023
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33. Supplementary Table 3 from Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Author

Pauli, Chantal, primary, Hopkins, Benjamin D., primary, Prandi, Davide, primary, Shaw, Reid, primary, Fedrizzi, Tarcisio, primary, Sboner, Andrea, primary, Sailer, Verena, primary, Augello, Michael, primary, Puca, Loredana, primary, Rosati, Rachele, primary, McNary, Terra J., primary, Churakova, Yelena, primary, Cheung, Cynthia, primary, Triscott, Joanna, primary, Pisapia, David, primary, Rao, Rema, primary, Mosquera, Juan Miguel, primary, Robinson, Brian, primary, Faltas, Bishoy M., primary, Emerling, Brooke E., primary, Gadi, Vijayakrishna K., primary, Bernard, Brady, primary, Elemento, Olivier, primary, Beltran, Himisha, primary, Demichelis, Francesca, primary, Kemp, Christopher J., primary, Grandori, Carla, primary, Cantley, Lewis C., primary, and Rubin, Mark A., primary

Published
2023
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34. Supplementary Table Legends from Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Author

Pauli, Chantal, primary, Hopkins, Benjamin D., primary, Prandi, Davide, primary, Shaw, Reid, primary, Fedrizzi, Tarcisio, primary, Sboner, Andrea, primary, Sailer, Verena, primary, Augello, Michael, primary, Puca, Loredana, primary, Rosati, Rachele, primary, McNary, Terra J., primary, Churakova, Yelena, primary, Cheung, Cynthia, primary, Triscott, Joanna, primary, Pisapia, David, primary, Rao, Rema, primary, Mosquera, Juan Miguel, primary, Robinson, Brian, primary, Faltas, Bishoy M., primary, Emerling, Brooke E., primary, Gadi, Vijayakrishna K., primary, Bernard, Brady, primary, Elemento, Olivier, primary, Beltran, Himisha, primary, Demichelis, Francesca, primary, Kemp, Christopher J., primary, Grandori, Carla, primary, Cantley, Lewis C., primary, and Rubin, Mark A., primary

Published
2023
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35. Supplementary Table 2 from Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Author

Pauli, Chantal, primary, Hopkins, Benjamin D., primary, Prandi, Davide, primary, Shaw, Reid, primary, Fedrizzi, Tarcisio, primary, Sboner, Andrea, primary, Sailer, Verena, primary, Augello, Michael, primary, Puca, Loredana, primary, Rosati, Rachele, primary, McNary, Terra J., primary, Churakova, Yelena, primary, Cheung, Cynthia, primary, Triscott, Joanna, primary, Pisapia, David, primary, Rao, Rema, primary, Mosquera, Juan Miguel, primary, Robinson, Brian, primary, Faltas, Bishoy M., primary, Emerling, Brooke E., primary, Gadi, Vijayakrishna K., primary, Bernard, Brady, primary, Elemento, Olivier, primary, Beltran, Himisha, primary, Demichelis, Francesca, primary, Kemp, Christopher J., primary, Grandori, Carla, primary, Cantley, Lewis C., primary, and Rubin, Mark A., primary

Published
2023
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36. Supplementary Table 6 from Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Author

Pauli, Chantal, primary, Hopkins, Benjamin D., primary, Prandi, Davide, primary, Shaw, Reid, primary, Fedrizzi, Tarcisio, primary, Sboner, Andrea, primary, Sailer, Verena, primary, Augello, Michael, primary, Puca, Loredana, primary, Rosati, Rachele, primary, McNary, Terra J., primary, Churakova, Yelena, primary, Cheung, Cynthia, primary, Triscott, Joanna, primary, Pisapia, David, primary, Rao, Rema, primary, Mosquera, Juan Miguel, primary, Robinson, Brian, primary, Faltas, Bishoy M., primary, Emerling, Brooke E., primary, Gadi, Vijayakrishna K., primary, Bernard, Brady, primary, Elemento, Olivier, primary, Beltran, Himisha, primary, Demichelis, Francesca, primary, Kemp, Christopher J., primary, Grandori, Carla, primary, Cantley, Lewis C., primary, and Rubin, Mark A., primary

Published
2023
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37. Supplementary Table 4 from Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Author

Pauli, Chantal, primary, Hopkins, Benjamin D., primary, Prandi, Davide, primary, Shaw, Reid, primary, Fedrizzi, Tarcisio, primary, Sboner, Andrea, primary, Sailer, Verena, primary, Augello, Michael, primary, Puca, Loredana, primary, Rosati, Rachele, primary, McNary, Terra J., primary, Churakova, Yelena, primary, Cheung, Cynthia, primary, Triscott, Joanna, primary, Pisapia, David, primary, Rao, Rema, primary, Mosquera, Juan Miguel, primary, Robinson, Brian, primary, Faltas, Bishoy M., primary, Emerling, Brooke E., primary, Gadi, Vijayakrishna K., primary, Bernard, Brady, primary, Elemento, Olivier, primary, Beltran, Himisha, primary, Demichelis, Francesca, primary, Kemp, Christopher J., primary, Grandori, Carla, primary, Cantley, Lewis C., primary, and Rubin, Mark A., primary

Published
2023
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38. Supplementary Table 5 from Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Author

Pauli, Chantal, primary, Hopkins, Benjamin D., primary, Prandi, Davide, primary, Shaw, Reid, primary, Fedrizzi, Tarcisio, primary, Sboner, Andrea, primary, Sailer, Verena, primary, Augello, Michael, primary, Puca, Loredana, primary, Rosati, Rachele, primary, McNary, Terra J., primary, Churakova, Yelena, primary, Cheung, Cynthia, primary, Triscott, Joanna, primary, Pisapia, David, primary, Rao, Rema, primary, Mosquera, Juan Miguel, primary, Robinson, Brian, primary, Faltas, Bishoy M., primary, Emerling, Brooke E., primary, Gadi, Vijayakrishna K., primary, Bernard, Brady, primary, Elemento, Olivier, primary, Beltran, Himisha, primary, Demichelis, Francesca, primary, Kemp, Christopher J., primary, Grandori, Carla, primary, Cantley, Lewis C., primary, and Rubin, Mark A., primary

Published
2023
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39. Supplementary Data from A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers

Author

Beltran, Himisha, primary, Oromendia, Clara, primary, Danila, Daniel C., primary, Montgomery, Bruce, primary, Hoimes, Christopher, primary, Szmulewitz, Russell Z., primary, Vaishampayan, Ulka, primary, Armstrong, Andrew J., primary, Stein, Mark, primary, Pinski, Jacek, primary, Mosquera, Juan M., primary, Sailer, Verena, primary, Bareja, Rohan, primary, Romanel, Alessandro, primary, Gumpeni, Naveen, primary, Sboner, Andrea, primary, Dardenne, Etienne, primary, Puca, Loredana, primary, Prandi, Davide, primary, Rubin, Mark A., primary, Scher, Howard I., primary, Rickman, David S., primary, Demichelis, Francesca, primary, Nanus, David M., primary, Ballman, Karla V., primary, and Tagawa, Scott T., primary

Published
2023
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41. Long-term taxane exposure and transdifferentiation of prostate cancer in vitro.

Author

Von Amsberg, Gunhild, primary, Dyshlovoy, Sergey, additional, Hauschild, Jessica, additional, Sailer, Verena, additional, Perner, Sven, additional, Offermann, Anne, additional, Merkens, Lina, additional, Krisp, Christoph, additional, Werner, Stefan, additional, Pantel, Klaus, additional, Kaune, Moritz, additional, Tilki, Derya, additional, Schlüter, Hartmut, additional, Graefen, Markus, additional, and Bokemeyer, Carsten, additional

Published
2023
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43. Experimental in vitro, ex vivo and in vivo models in prostate cancer research

Author

Sailer, Verena, primary, von Amsberg, Gunhild, additional, Duensing, Stefan, additional, Kirfel, Jutta, additional, Lieb, Verena, additional, Metzger, Eric, additional, Offermann, Anne, additional, Pantel, Klaus, additional, Schuele, Roland, additional, Taubert, Helge, additional, Wach, Sven, additional, Perner, Sven, additional, Werner, Stefan, additional, and Aigner, Achim, additional

Published
2022
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45. The Gene Expression Landscape of Prostate Cancer BM Reveals Close Interaction with the Bone Microenvironment

Author

Saraji, Alireza, primary, Duan, Kang, additional, Watermann, Christian, additional, Hempel, Katharina, additional, Roesch, Marie C., additional, Krupar, Rosemarie, additional, Stegmann-Frehse, Janine, additional, Jonigk, Danny, additional, Kuehnel, Mark Philipp, additional, Klapper, Wolfram, additional, Merseburger, Axel S., additional, Kirfel, Jutta, additional, Perner, Sven, additional, Offermann, Anne, additional, and Sailer, Verena, additional

Published
2022
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47. Targeting cyclin-dependent kinase 7—association between CDK7 and pMED1 expression in prostate cancer tissue

Author

Paulsen, Finn-Ole, primary, Kang, Duan, additional, Becker, Finn, additional, Roth, Doris, additional, Joerg, Vincent, additional, Dreyer, Eva, additional, Roesch, Marie C, additional, Seidel, Christoph, additional, Merseburger, Axel S, additional, Kirfel, Jutta, additional, Sailer, Verena, additional, Offermann, Anne, additional, and Perner, Sven, additional

Published
2022
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48. Bone biopsy protocol for advanced prostate cancer in the era of precision medicine

Author

Sailer, Verena, Schiffman, Marc H., Kossai, Myriam, Cyrta, Joanna, Beg, Shaham, Sullivan, Brian, Pua, Bradley B., Lee, Kyungmouk Steve, Talenfeld, Adam D., Nanus, David M., Tagawa, Scott T., Robinson, Brian D., Rao, Rema A., Pauli, Chantal, Bareja, Rohan, Beltran, Luis S., Sigaras, Alexandros, Eng, Kenneth Wa, Elemento, Olivier, Sboner, Andrea, Rubin, Mark A., Beltran, Himisha, and Mosquera, Juan Miguel

Published
2018
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50. Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci

Author

Fontugne, Jacqueline, primary, Cai, Peter Y., additional, Alnajar, Hussein, additional, Bhinder, Bhavneet, additional, Park, Kyung, additional, Ye, Huihui, additional, Beg, Shaham, additional, Sailer, Verena, additional, Siddiqui, Javed, additional, Blattner-Johnson, Mirjam, additional, Croyle, Jaclyn A., additional, Noorzad, Zohal, additional, Calagua, Carla, additional, MacDonald, Theresa Y., additional, Axcrona, Ulrika, additional, Bogaard, Mari, additional, Axcrona, Karol, additional, Scherr, Douglas S., additional, Sanda, Martin G., additional, Johannessen, Bjarne, additional, Chinnaiyan, Arul M., additional, Elemento, Olivier, additional, Skotheim, Rolf I., additional, Rubin, Mark A., additional, Barbieri, Christopher E., additional, and Mosquera, Juan Miguel, additional

Published
2022
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