151 results on '"Saint-Marc, Olivier"'
Search Results
2. Impact of patient age on outcome of minimally invasive versus open pancreatoduodenectomy: a propensity score matched study
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Emmen, Anouk M.L.H., Jones, Leia R., Wei, Kongyuan, Busch, Olivier, Shen, Baiyong, Fusai, Giuseppe K., Shyr, Yi-Ming, Khatkov, Igor, White, Steve, Boggi, Ugo, Kerem, Mustafa, Molenaar, I.Q., Koerkamp, Bas G., Saint-Marc, Olivier, Dokmak, Safi, van Dieren, Susan, Rozzini, Renzo, Festen, Sebastiaan, Liu, Rong, Jang, Jin-Young, Besselink, Marc G., and Hilal, Mohammed A.
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- 2025
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3. Learning curve stratified outcomes after robotic pancreatoduodenectomy: International multicenter experience
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Jones, Leia R., Zwart, Maurice J.W., de Graaf, Nine, Wei, Kongyuan, Qu, Liu, Jiabin, Jin, Ningzhen, Fu, Wang, Shin-E, Kim, Hongbeom, Kauffmann, Emanuele F., de Wilde, Roeland F., Molenaar, I. Quintus, Chao, Ying Jui, Moraldi, Luca, Saint-Marc, Olivier, Nickel, Felix, Peng, Cheng-Ming, Kang, Chang Moo, Machado, Marcel, Luyer, Misha D.P., Lips, Daan J., Bonsing, Bert A., Hackert, Thilo, Shan, Yan-Shen, Groot Koerkamp, Bas, Shyr, Yi-Ming, Shen, Baiyong, Boggi, Ugo, Liu, Rong, Jang, Jin-Young, Besselink, Marc G., and Abu Hilal, Mohammad
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- 2024
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4. Short-term results of robot-assisted pancreatoduodeodenectomy: a retrospective cohort study of 146 patients operated in a high-volume center
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Iben-khayat, Abdallah, Felli, Emanuelle, Thebault, Baudouin, Facques, Amaury, Najah, Haythem, and Saint-Marc, Olivier
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- 2024
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5. Robot-assisted versus laparoscopic pancreatoduodenectomy: a pan-European multicenter propensity-matched study
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Manzoni, Alberto, Guerra, Martina, Daams, Freek, Kazemier, Geert, Izrailov, Roman, Efanov, Mikhail, Napoli, Niccolò, Ginesini, Michael, Cappelle, Marie, Haen, Roel, Quetel, Romain, Pucci, Marco, Derksen, Wouter., Hagendoorn, Jeroen, Ftériche, Fadhel Samir, Muzzolini, Milena, Vansteenkiste, Franky, Bolm, Louisa, Winkel, Maike ten, Giani, Alessandro, Calcagno, Pietro, Emmen, Anouk M.L.H., Zwart, Maurice J.W., Khatkov, Igor E., Boggi, Ugo, Groot Koerkamp, Bas, Busch, Olivier R., Saint-Marc, Olivier, Dokmak, Safi, Molenaar, I. Quintus, D’Hondt, Mathieu, Ramera, Marco, Keck, Tobias, Ferrari, Giovanni, Luyer, Misha D.P., Moraldi, Luca, Ielpo, Benedetto, Wittel, Uwe, Souche, Francois-Regis, Hackert, Thilo, Lips, Daan, Can, Mehmet Fatih, Bosscha, Koop, Fara, Regis, Festen, Sebastiaan, van Dieren, Susan, Coratti, Andrea, De Hingh, Ignace, Mazzola, Michele, Wellner, Ulrich, De Meyere, Celine, van Santvoort, Hjalmar C., Aussilhou, Béatrice, Ibenkhayat, Abdallah, de Wilde, Roeland F., Kauffmann, Emanuele F., Tyutyunnik, Pavel, Besselink, Marc G., and Abu Hilal, Mohammad
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- 2024
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6. Surgical Techniques and Related Perioperative Outcomes After Robot-assisted Minimally Invasive Gastrectomy (RAMIG): Results From the Prospective Multicenter International Ugira Gastric Registry
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de Jongh, Cas, Cianchi, Fabio, Kinoshita, Takahiro, Kingma, Feike, Piccoli, Micaela, Dubecz, Attila, Kouwenhoven, Ewout, van Det, Marc, Mala, Tom, Coratti, Andrea, Ubiali, Paolo, Turner, Paul, Kish, Pursnani, Borghi, Felice, Immanuel, Arul, Nilsson, Magnus, Rouvelas, Ioannis, Holzen, Jens P., Rouanet, Philippe, Saint-Marc, Olivier, Dussart, David, Patriti, Alberto, Bazzocchi, Francesca, van Etten, Boudewijn, Haveman, Jan W., DePrizio, Marco, Sabino, Flávio, Viola, Massimo, Berlth, Felix, Grimminger, Peter P., Roviello, Franco, van Hillegersberg, Richard, Ruurda, Jelle, Barbato, Giuseppe, Takeuchi, Tamae, Yura, Masahiro, Pecchini, Francesca, Mullineris, Barbara, Kemeter, Melissa, Giulini, Luca, Førland, Dag, Di Marino, Michele, Tribuzi, Angela, Maffeis, Federica, Velkoski, Jaqueline, Sarantitis, Ioannis, Marano, Alessandra, Robella, Manuela, Jaretzke, Helen, Ri, Motonari, Juratli, Mazen, Mourregot, Anne, Petrelli, Filippo, Biancafarina, Alessia, Barbieri, Vittoria, Uzun, Eren, Marano, Luigi, d’Ignazio, Alessia, and Resca, Luca
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- 2024
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7. The PD-ROBOSCORE: A difficulty score for robotic pancreatoduodenectomy
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Napoli, Niccolò, Cacace, Concetta, Kauffmann, Emanuele F., Jones, Leia, Ginesini, Michael, Gianfaldoni, Cesare, Salamone, Alice, Asta, Fabio, Ripolli, Allegra, Di Dato, Armando, Busch, Olivier R., Cappelle, Marie L., Chao, Ying Jui, de Wilde, Roeland F., Hackert, Thilo, Jang, Jin-Young, Koerkamp, Bas Groot, Kwon, Wooil, Lips, Daan, Luyer, Misha D.P., Nickel, Felix, Saint-Marc, Olivier, Shan, Yan-Shen, Shen, Baiyong, Vistoli, Fabio, Besselink, Marc G., Hilal, Mohammad Abu, and Boggi, Ugo
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- 2023
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8. The Brescia Internationally Validated European Guidelines on Minimally Invasive Pancreatic Surgery (EGUMIPS)
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Abu Hilal, Mohammad, van Ramshorst, Tess M.E., Boggi, Ugo, Dokmak, Safi, Edwin, Bjørn, Keck, Tobias, Khatkov, Igor, Ahmad, Jawad, Al Saati, Hani, Alseidi, Adnan, Azagra, Juan S., Björnsson, Bergthor, Can, Fatih M., D’Hondt, Mathieu, Efanov, Mikhail, Espin Alvarez, Francisco, Esposito, Alessandro, Ferrari, Giovanni, Groot Koerkamp, Bas, Gumbs, Andrew A., Hogg, Melissa E., Huscher, Cristiano G.S., Ielpo, Benedetto, Ivanecz, Arpad, Jang, Jin-Young, Liu, Rong, Luyer, Misha D.P., Menon, Krishna, Nakamura, Masafumi, Piardi, Tullio, Saint-Marc, Olivier, White, Steve, Yoon, Yoo-Seok, Zerbi, Alessandro, Bassi, Claudio, Berrevoet, Frederik, Chan, Carlos, Coimbra, Felipe J., Conlon, Kevin C.P., Cook, Andrew, Dervenis, Christos, Falconi, Massimo, Ferrari, Clarissa, Frigerio, Isabella, Fusai, Giuseppe K., De Oliveira, Michelle L., Pinna, Antonio D., Primrose, John N., Sauvanet, Alain, Serrablo, Alejandro, Smadi, Sameer, Badran, Ali, Baychorov, Magomet, Bannone, Elisa, van Bodegraven, Eduard A., Emmen, Anouk M.L.H., Giani, Alessandro, de Graaf, Nine, van Hilst, Jony, Jones, Leia R., Levi Sandri, Giovanni B., Pulvirenti, Alessandra, Ramera, Marco, Rashidian, Niki, Sahakyan, Mushegh A., Uijterwijk, Bas A., Zampedri, Pietro, Zwart, Maurice J.W., Alfieri, Sergio, Berti, Stefano, Butturini, Giovanni, Di Benedetto, Fabrizio, Ettorre, Giuseppe M., Giuliante, Felice, Jovine, Elio, Memeo, Riccardo, Portolani, Nazario, Ruzzenente, Andrea, Salvia, Roberto, Siriwardena, Ajith K., Besselink, Marc G., Asbun, Horacio J., Over, Paul, Saleh, Omar, and Rivizzigno, Piero
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- 2024
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9. The Feasibility, Proficiency, and Mastery Learning Curves in 635 Robotic Pancreatoduodenectomies Following a Multicenter Training Program: “Standing on the Shoulders of Giants”
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Zwart, Maurice J.W., van den Broek, Bram, de Graaf, Nine, Suurmeijer, José A., Augustinus, Simone, te Riele, Wouter W., van Santvoort, Hjalmar C., Hagendoorn, Jeroen, Borel Rinkes, Inne H.M., van Dam, Jacob L., Takagi, Kosei, Tran, Khé T.C., Schreinemakers, Jennifer, van der Schelling, George, Wijsman, Jan H., de Wilde, Roeland F., Festen, Sebastiaan, Daams, Freek, Luyer, Misha D., de Hingh, Ignace H.J.T., Mieog, Jan S.D., Bonsing, Bert A., Lips, Daan J., Abu Hilal, Mohamed, Busch, Olivier R., Saint-Marc, Olivier, Zeh, Herbert J., III, Zureikat, Amer H., Hogg, Melissa E., Koerkamp, Bas G., Molenaar, Isaac Q., and Besselink, Marc G.
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- 2023
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10. Use and outcome of minimally invasive pancreatic surgery in the European E-MIPS registry
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Vilhav, Caroline, Hartman, Vera, Kirkegård, Jakob, Sergeant, Gregory, Kleeff, Jörg, Coolsen, Marielle, Coppola, Roberto, Pauletti, Bruno, Mittermair, Christof, Tingstedt, Bobby, Erkan, Mert, Tomazic, Ales, Korkolis, Dimitris, van der Heijde, Nicky, Vissers, Frederique L., Manzoni, Alberto, Zimmitti, Giuseppe, Balsells, Joaquim, Berrevoet, Frederik, Bjornsson, Bergthor, van den Boezem, Peter, Boggi, Ugo, Bratlie, Svein O., Burdio, Fernando, Coratti, Andrea, D'Hondt, Mathieu, Del Pozo, Carlos D., Dokmak, Safi, Fara, Regis, Can, Mehmet F., Festen, Sebastiaan, Forgione, Antonello, Fristrup, Claus, Gaujoux, Sebastien, Groot Koerkamp, Bas, Hackert, Thilo, Khatkov, Igor E., Keck, Tobias, Seppänen, Hanna, Lips, Daan, Luyer, Misha, Pittau, Gabriella, Maglione, Manuel, Molenaar, I. Quintus, Pessaux, Patrick, Roeyen, Geert, Saint-Marc, Olivier, Cabus, Santiago S., van Santvoort, Hjalmar, van der Schelling, George, Serradilla-Martin, Mario, Souche, Francois-regis, Suarez Muñoz, Miguel Á., Marino, Marco V., Besselink, Marc G., and Abu Hilal, Mohammed
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- 2023
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11. Robotic Distal Pancreatectomy: A Novel Standard of Care? Benchmark Values for Surgical Outcomes From 16 International Expert Centers
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Müller, Philip C., Breuer, Eva, Nickel, Felix, Zani, Sabino, Jr, Kauffmann, Emanuele, De Franco, Lorenzo, Tschuor, Christoph, Krohn, Paul Suno, Burgdorf, Stefan K., Jonas, Jan Philipp, Oberkofler, Christian E., Petrowsky, Henrik, Saint-Marc, Olivier, Seelen, Leonard, Molenaar, Izaak Quintus, Wellner, Ulrich, Keck, Tobias, Coratti, Andrea, van Dam, Jacob L., de Wilde, Roeland, Koerkamp, Bas Groot, Valle, Valentina, Giulianotti, Pier, Ghabi, Elie, Moskal, David, Lavu, Harish, Vrochides, Dionisios, Martinie, John, Yeo, Charles, Sánchez-Velázquez, Patricia, Ielpo, Benedetto, Ajay, Pranay S., Shah, Mihir M., Kooby, David A., Gao, Song, Hao, Jihui, He, Jin, Boggi, Ugo, Hackert, Thilo, Allen, Peter, Borel-Rinkes, Inne H.M., and Clavien, Pierre Alain
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- 2023
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12. Outcomes of a Multicenter Training Program in Robotic Pancreatoduodenectomy (LAELAPS-3)
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Zwart, Maurice J.W., Nota, Carolijn L.M., de Rooij, Thijs, van Hilst, Jony, te Riele, Wouter W., van Santvoort, Hjalmar C., Hagendoorn, Jeroen, Borei Rinkes, Inne H.M., van Dam, Jacob L., Latenstein, Anouk E.J., Takagi, Kosei, Tran, Khé T.C., Schreinemakers, Jennifer, van der Schelling, George P., Wijsman, Jan H., Festen, Sebastiaan, Daams, Freek, Luyer, Misha D., de Hingh, Ignace H.J.T., Mieog, Jan S.D., Bonsing, Bert A., Lips, Daan J., Hilal, Mohammed Abu, Busch, Olivier R., Saint-Marc, Olivier, Zehl, Herbert J., II, Zureikat, Amer H., Hogg, Melissa E., Molenaar, I. Quintus, Besselink, Marc G., and Koerkamp, Bas Groot
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- 2022
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13. Standardizing definitions and terminology of left-sided pancreatic resections through an international Delphi consensus
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van Ramshorst, Tess M E, primary, van Hilst, Jony, additional, Boggi, Ugo, additional, Dokmak, Safi, additional, Edwin, Bjørn, additional, Keck, Tobias, additional, Khatkov, Igor, additional, Balduzzi, Alberto, additional, Pulvirenti, Alessandra, additional, Ahmad, Jawad, additional, Al Saati, Hani, additional, Alseidi, Adnan, additional, Ausania, Fabio, additional, Azagra, Juan S, additional, Balzano, Gianpaolo, additional, Björnsson, Bergthor, additional, Can, Fatih M, additional, Cillo, Umberto, additional, D’Hondt, Mathieu, additional, Efanov, Mikhail, additional, Erkan, Mert, additional, Espin Alvarez, Francisco, additional, Esposito, Alessandro, additional, Ferrari, Giovanni, additional, Groot Koerkamp, Bas, additional, Gumbs, Andrew A, additional, Hogg, Melissa E, additional, Ielpo, Benedetto, additional, Ivanecz, Arpad, additional, Jang, Jin-Young, additional, Kleive, Dyre, additional, Kooby, David A, additional, Luyer, Misha D P, additional, Marchegiani, Giovanni, additional, Menon, Krishna, additional, Molenaar, I Quintus, additional, Nagakawa, Yuichi, additional, Nakamura, Masafumi, additional, Palumbo, Diego, additional, Piardi, Tullio, additional, Ramia, Jose M, additional, Saint-Marc, Olivier, additional, Salti, George I, additional, Strobel, Oliver, additional, Vollmer, Charles M, additional, Wei, Alice C, additional, White, Steve, additional, Yoon, Yoo-Seok, additional, Zerbi, Alessandro, additional, Bassi, Claudio, additional, Berrevoet, Frederik, additional, Chan, Carlos, additional, Coimbra, Felipe J, additional, Conlon, Kevin C P, additional, Dervenis, Christos, additional, Falconi, Massimo, additional, Frigerio, Isabella, additional, Fusai, Giuseppe K, additional, De Oliveira, Michelle L, additional, Pinna, Antonio D, additional, Primrose, John N, additional, Sauvanet, Alain, additional, Serrablo, Alejandro, additional, Smadi, Sameer, additional, Alfieri, Sergio, additional, Berti, Stefano, additional, Butturini, Giovanni, additional, Casadei, Riccardo, additional, Coppola, Roberto, additional, Di Benedetto, Fabrizio, additional, Ettorre, Giuseppe M, additional, Giuliante, Felice, additional, Jovine, Elio, additional, Memeo, Riccardo, additional, Pietrabissa, Andrea, additional, Portolani, Nazario, additional, Salvia, Roberto, additional, Siriwardena, Ajith K, additional, Asbun, Horacio J, additional, Besselink, Marc G, additional, and Abu Hilal, Mohammad, additional
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- 2024
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14. Robot-assisted versus laparoscopic pancreatoduodenectomy: a pan-European multicenter propensity-matched study
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Emmen, Anouk M.L.H., primary, Zwart, Maurice J.W., additional, Khatkov, Igor E., additional, Boggi, Ugo, additional, Groot Koerkamp, Bas, additional, Busch, Olivier R., additional, Saint-Marc, Olivier, additional, Dokmak, Safi, additional, Molenaar, I. Quintus, additional, D’Hondt, Mathieu, additional, Ramera, Marco, additional, Keck, Tobias, additional, Ferrari, Giovanni, additional, Luyer, Misha D.P., additional, Moraldi, Luca, additional, Ielpo, Benedetto, additional, Wittel, Uwe, additional, Souche, Francois-Regis, additional, Hackert, Thilo, additional, Lips, Daan, additional, Can, Mehmet Fatih, additional, Bosscha, Koop, additional, Fara, Regis, additional, Festen, Sebastiaan, additional, van Dieren, Susan, additional, Coratti, Andrea, additional, De Hingh, Ignace, additional, Mazzola, Michele, additional, Wellner, Ulrich, additional, De Meyere, Celine, additional, van Santvoort, Hjalmar C., additional, Aussilhou, Béatrice, additional, Ibenkhayat, Abdallah, additional, de Wilde, Roeland F., additional, Kauffmann, Emanuele F., additional, Tyutyunnik, Pavel, additional, Besselink, Marc G., additional, Abu Hilal, Mohammad, additional, Manzoni, Alberto, additional, Guerra, Martina, additional, Daams, Freek, additional, Kazemier, Geert, additional, Izrailov, Roman, additional, Efanov, Mikhail, additional, Napoli, Niccolò, additional, Ginesini, Michael, additional, Cappelle, Marie, additional, Haen, Roel, additional, Quetel, Romain, additional, Pucci, Marco, additional, Derksen, Wouter., additional, Hagendoorn, Jeroen, additional, Ftériche, Fadhel Samir, additional, Muzzolini, Milena, additional, Vansteenkiste, Franky, additional, Bolm, Louisa, additional, Winkel, Maike ten, additional, Giani, Alessandro, additional, and Calcagno, Pietro, additional
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- 2024
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15. Standardizing definitions and terminology of left-sided pancreatic resections through an international Delphi consensus
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MS CGO, Cancer, van Ramshorst, Tess M.E., van Hilst, Jony, Boggi, Ugo, Dokmak, Safi, Edwin, Bjørn, Keck, Tobias, Khatkov, Igor, Balduzzi, Alberto, Pulvirenti, Alessandra, Ahmad, Jawad, Saati, Hani Al, Alseidi, Adnan, Ausania, Fabio, Azagra, Juan S., Balzano, Gianpaolo, Björnsson, Bergthor, Can, Fatih M., Cillo, Umberto, D’Hondt, Mathieu, Efanov, Mikhail, Erkan, Mert, Alvarez, Francisco Espin, Esposito, Alessandro, Ferrari, Giovanni, Koerkamp, Bas Groot, Gumbs, Andrew A., Hogg, Melissa E., Ielpo, Benedetto, Ivanecz, Arpad, Jang, Jin Young, Kleive, Dyre, Kooby, David A., Luyer, Misha D.P., Marchegiani, Giovanni, Menon, Krishna, Molenaar, I. Quintus, Nagakawa, Yuichi, Nakamura, Masafumi, Palumbo, Diego, Piardi, Tullio, Ramia, Jose M., Saint-Marc, Olivier, Salti, George I., Strobel, Oliver, Vollmer, Charles M., Wei, Alice C., White, Steve, Yoon, Yoo Seok, Zerbi, Alessandro, Bassi, Claudio, Berrevoet, Frederik, Chan, Carlos, Coimbra, Felipe J., Conlon, Kevin C.P., Dervenis, Christos, Falconi, Massimo, Frigerio, Isabella, Fusai, Giuseppe K., De Oliveira, Michelle L., Pinna, Antonio D., Primrose, John N., Sauvanet, Alain, Serrablo, Alejandro, Smadi, Sameer, Alfieri, Sergio, Berti, Stefano, Butturini, Giovanni, Casadei, Riccardo, Coppola, Roberto, Benedetto, Fabrizio Di, Ettorre, Giuseppe M., Giuliante, Felice, Jovine, Elio, Memeo, Riccardo, Pietrabissa, Andrea, Portolani, Nazario, Salvia, Roberto, Siriwardena, Ajith K., Asbun, Horacio J., Besselink, Marc G., Hilal, Mohammad Abu, MS CGO, Cancer, van Ramshorst, Tess M.E., van Hilst, Jony, Boggi, Ugo, Dokmak, Safi, Edwin, Bjørn, Keck, Tobias, Khatkov, Igor, Balduzzi, Alberto, Pulvirenti, Alessandra, Ahmad, Jawad, Saati, Hani Al, Alseidi, Adnan, Ausania, Fabio, Azagra, Juan S., Balzano, Gianpaolo, Björnsson, Bergthor, Can, Fatih M., Cillo, Umberto, D’Hondt, Mathieu, Efanov, Mikhail, Erkan, Mert, Alvarez, Francisco Espin, Esposito, Alessandro, Ferrari, Giovanni, Koerkamp, Bas Groot, Gumbs, Andrew A., Hogg, Melissa E., Ielpo, Benedetto, Ivanecz, Arpad, Jang, Jin Young, Kleive, Dyre, Kooby, David A., Luyer, Misha D.P., Marchegiani, Giovanni, Menon, Krishna, Molenaar, I. Quintus, Nagakawa, Yuichi, Nakamura, Masafumi, Palumbo, Diego, Piardi, Tullio, Ramia, Jose M., Saint-Marc, Olivier, Salti, George I., Strobel, Oliver, Vollmer, Charles M., Wei, Alice C., White, Steve, Yoon, Yoo Seok, Zerbi, Alessandro, Bassi, Claudio, Berrevoet, Frederik, Chan, Carlos, Coimbra, Felipe J., Conlon, Kevin C.P., Dervenis, Christos, Falconi, Massimo, Frigerio, Isabella, Fusai, Giuseppe K., De Oliveira, Michelle L., Pinna, Antonio D., Primrose, John N., Sauvanet, Alain, Serrablo, Alejandro, Smadi, Sameer, Alfieri, Sergio, Berti, Stefano, Butturini, Giovanni, Casadei, Riccardo, Coppola, Roberto, Benedetto, Fabrizio Di, Ettorre, Giuseppe M., Giuliante, Felice, Jovine, Elio, Memeo, Riccardo, Pietrabissa, Andrea, Portolani, Nazario, Salvia, Roberto, Siriwardena, Ajith K., Asbun, Horacio J., Besselink, Marc G., and Hilal, Mohammad Abu
- Published
- 2024
16. Standardizing definitions and terminology of left-sided pancreatic resections through an international Delphi consensus
- Author
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van Ramshorst, Tess M. E., van Hilst, Jony, Boggi, Ugo, Dokmak, Safi, Edwin, Bjorn, Keck, Tobias, Khatkov, Igor, Balduzzi, Alberto, Pulvirenti, Alessandra, Ahmad, Jawad, Al Saati, Hani, Alseidi, Adnan, Ausania, Fabio, Azagra, Juan S., Balzano, Gianpaolo, Björnsson, Bergthor, Can, Fatih M., Cillo, Umberto, D'Hondt, Mathieu, Efanov, Mikhail, Erkan, Mert, Espin Alvarez, Francisco, Esposito, Alessandro, Ferrari, Giovanni, Groot Koerkamp, Bas, Gumbs, Andrew A., Hogg, Melissa E., Ielpo, Benedetto, Ivanecz, Arpad, Jang, Jin-Young, Kleive, Dyre, Kooby, David A., Luyer, Misha D. P., Marchegiani, Giovanni, Menon, Krishna, Molenaar, I. Quintus, Nagakawa, Yuichi, Nakamura, Masafumi, Palumbo, Diego, Piardi, Tullio, Ramia, Jose M., Saint-Marc, Olivier, Salti, George I, Strobel, Oliver, Vollmer, Charles M., Wei, Alice C., White, Steve, Yoon, Yoo-Seok, Zerbi, Alessandro, Bassi, Claudio, Berrevoet, Frederik, Chan, Carlos, Coimbra, Felipe J., Conlon, Kevin C. P., Dervenis, Christos, Falconi, Massimo, Frigerio, Isabella, Fusai, Giuseppe K., De Oliveira, Michelle L., Pinna, Antonio D., Primrose, John N., Sauvanet, Alain, Serrablo, Alejandro, Smadi, Sameer, Alfieri, Sergio, Berti, Stefano, Butturini, Giovanni, Casadei, Riccardo, Coppola, Roberto, Di Benedetto, Fabrizio, Ettorre, Giuseppe M., Giuliante, Felice, Jovine, Elio, Memeo, Riccardo, Pietrabissa, Andrea, Portolani, Nazario, Salvia, Roberto, Siriwardena, Ajith K., Asbun, Horacio J., Besselink, Marc G., Abu Hilal, Mohammad, van Ramshorst, Tess M. E., van Hilst, Jony, Boggi, Ugo, Dokmak, Safi, Edwin, Bjorn, Keck, Tobias, Khatkov, Igor, Balduzzi, Alberto, Pulvirenti, Alessandra, Ahmad, Jawad, Al Saati, Hani, Alseidi, Adnan, Ausania, Fabio, Azagra, Juan S., Balzano, Gianpaolo, Björnsson, Bergthor, Can, Fatih M., Cillo, Umberto, D'Hondt, Mathieu, Efanov, Mikhail, Erkan, Mert, Espin Alvarez, Francisco, Esposito, Alessandro, Ferrari, Giovanni, Groot Koerkamp, Bas, Gumbs, Andrew A., Hogg, Melissa E., Ielpo, Benedetto, Ivanecz, Arpad, Jang, Jin-Young, Kleive, Dyre, Kooby, David A., Luyer, Misha D. P., Marchegiani, Giovanni, Menon, Krishna, Molenaar, I. Quintus, Nagakawa, Yuichi, Nakamura, Masafumi, Palumbo, Diego, Piardi, Tullio, Ramia, Jose M., Saint-Marc, Olivier, Salti, George I, Strobel, Oliver, Vollmer, Charles M., Wei, Alice C., White, Steve, Yoon, Yoo-Seok, Zerbi, Alessandro, Bassi, Claudio, Berrevoet, Frederik, Chan, Carlos, Coimbra, Felipe J., Conlon, Kevin C. P., Dervenis, Christos, Falconi, Massimo, Frigerio, Isabella, Fusai, Giuseppe K., De Oliveira, Michelle L., Pinna, Antonio D., Primrose, John N., Sauvanet, Alain, Serrablo, Alejandro, Smadi, Sameer, Alfieri, Sergio, Berti, Stefano, Butturini, Giovanni, Casadei, Riccardo, Coppola, Roberto, Di Benedetto, Fabrizio, Ettorre, Giuseppe M., Giuliante, Felice, Jovine, Elio, Memeo, Riccardo, Pietrabissa, Andrea, Portolani, Nazario, Salvia, Roberto, Siriwardena, Ajith K., Asbun, Horacio J., Besselink, Marc G., and Abu Hilal, Mohammad
- Abstract
Funding Agencies|Intuitive grant for the LEARNBOT European Robotic Pancreatoduodenectomy training programme; DIPLOMA-2 trial; E-MIPS Registry; Medtronic grant for the investigator-initiated DIPLOMA trial; Ethicon grant for the PANDORINA trial; Intuitive for robotic pancreatoduodenectomy training
- Published
- 2024
- Full Text
- View/download PDF
17. Implementation and outcome of minimally invasive pancreatoduodenectomy in Europe:a registry-based retrospective study A critical appraisal of the first 3 years of the E-MIPS registry
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Emmen, Anouk M L H, de Graaf, Nine, Khatkov, I E, Busch, O R, Dokmak, S, Boggi, Ugo, Groot Koerkamp, Bas, Ferrari, Giovanni, Molenaar, I Q, Saint-Marc, Olivier, Ramera, Marco, Lips, Daan J, Mieog, J S D, Luyer, Misha D P, Keck, Tobias, D'Hondt, Mathieu, Souche, F R, Edwin, Bjørn, Hackert, Thilo, Liem, M S L, Iben-Khayat, Abdallah, van Santvoort, H C, Mazzola, Michele, de Wilde, Roeland F, Kauffmann, E F, Aussilhou, Beatrice, Festen, Sebastiaan, Izrailov, R, Tyutyunnik, P, Besselink, M G, Abu Hilal, Mohammad, Emmen, Anouk M L H, de Graaf, Nine, Khatkov, I E, Busch, O R, Dokmak, S, Boggi, Ugo, Groot Koerkamp, Bas, Ferrari, Giovanni, Molenaar, I Q, Saint-Marc, Olivier, Ramera, Marco, Lips, Daan J, Mieog, J S D, Luyer, Misha D P, Keck, Tobias, D'Hondt, Mathieu, Souche, F R, Edwin, Bjørn, Hackert, Thilo, Liem, M S L, Iben-Khayat, Abdallah, van Santvoort, H C, Mazzola, Michele, de Wilde, Roeland F, Kauffmann, E F, Aussilhou, Beatrice, Festen, Sebastiaan, Izrailov, R, Tyutyunnik, P, Besselink, M G, and Abu Hilal, Mohammad
- Abstract
BACKGROUND: International multicenter audit-based studies focusing on the outcome of minimally invasive pancreatoduodenectomy (MIPD) are lacking. The European Registry for Minimally Invasive Pancreatic Surgery (E-MIPS) is the E-AHPBA endorsed registry aimed to monitor and safeguard the introduction of MIPD in Europe. MATERIALS AND METHODS: A planned analysis of outcomes among consecutive patients after MIPD from 45 centers in 14 European countries in the E-MIPS registry (2019-2021). The main outcomes of interest were major morbidity (Clavien-Dindo grade ≥3) and 30-day/in-hospital mortality. RESULTS: Overall, 1336 patients after MIPD were included [835 robot-assisted (R-MIPD) and 501 laparoscopic MIPD (L-MIPD)]. Overall, 20 centers performed R-MIPD, 15 centers L-MIPD, and 10 centers both. Between 2019 and 2021, the rate of centers performing L-MIPD decreased from 46.9 to 25%, whereas for R-MIPD this increased from 46.9 to 65.6%. Overall, the rate of major morbidity was 41.2%, 30-day/in-hospital mortality 4.5%, conversion rate 9.7%, postoperative pancreatic fistula grade B/C 22.7%, and postpancreatectomy hemorrhage grade B/C 10.8%. Median length of hospital stay was 12 days (IQR 8-21). A lower rate of major morbidity, postoperative pancreatic fistula grade B/C, postpancreatectomy hemorrhage grade B/C, delayed gastric emptying grade B/C, percutaneous drainage, and readmission was found after L-MIPD. The number of centers meeting the Miami Guidelines volume cut-off of ≥20 MIPDs annually increased from 9 (28.1%) in 2019 to 12 (37.5%) in 2021 ( P =0.424). Rates of conversion (7.4 vs. 14.8% P <0.001) and reoperation (8.9 vs. 15.1% P <0.001) were lower in centers, which fulfilled the Miami volume cut-off. CONCLUSION: During the first 3 years of the pan-European E-MIPS registry, morbidity and mortality rates after MIPD were acceptable. A shift is ongoing from L-MIPD to R-MIPD. Variations in outcomes between the two minimally invasive approaches and the impact of the
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- 2024
18. Robot-assisted versus laparoscopic pancreatoduodenectomy:a pan-European multicenter propensity-matched study
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Emmen, Anouk M.L.H., Zwart, Maurice J.W., Khatkov, Igor E., Boggi, Ugo, Groot Koerkamp, Bas, Busch, Olivier R., Saint-Marc, Olivier, Dokmak, Safi, Molenaar, I. Quintus, D'Hondt, Mathieu, Ramera, Marco, Keck, Tobias, Ferrari, Giovanni, Luyer, Misha D.P., Moraldi, Luca, Ielpo, Benedetto, Wittel, Uwe, Souche, Francois Regis, Hackert, Thilo, Lips, Daan, Can, Mehmet Fatih, Bosscha, Koop, Fara, Regis, Festen, Sebastiaan, van Dieren, Susan, Coratti, Andrea, De Hingh, Ignace, Mazzola, Michele, Wellner, Ulrich, De Meyere, Celine, van Santvoort, Hjalmar C., Aussilhou, Béatrice, Ibenkhayat, Abdallah, de Wilde, Roeland F., Kauffmann, Emanuele F., Tyutyunnik, Pavel, Besselink, Marc G., Abu Hilal, Mohammad, Manzoni, Alberto, Guerra, Martina, Daams, Freek, Kazemier, Geert, Izrailov, Roman, Efanov, Mikhail, Napoli, Niccolò, Ginesini, Michael, Cappelle, Marie, Haen, Roel, Quetel, Romain, Pucci, Marco, Emmen, Anouk M.L.H., Zwart, Maurice J.W., Khatkov, Igor E., Boggi, Ugo, Groot Koerkamp, Bas, Busch, Olivier R., Saint-Marc, Olivier, Dokmak, Safi, Molenaar, I. Quintus, D'Hondt, Mathieu, Ramera, Marco, Keck, Tobias, Ferrari, Giovanni, Luyer, Misha D.P., Moraldi, Luca, Ielpo, Benedetto, Wittel, Uwe, Souche, Francois Regis, Hackert, Thilo, Lips, Daan, Can, Mehmet Fatih, Bosscha, Koop, Fara, Regis, Festen, Sebastiaan, van Dieren, Susan, Coratti, Andrea, De Hingh, Ignace, Mazzola, Michele, Wellner, Ulrich, De Meyere, Celine, van Santvoort, Hjalmar C., Aussilhou, Béatrice, Ibenkhayat, Abdallah, de Wilde, Roeland F., Kauffmann, Emanuele F., Tyutyunnik, Pavel, Besselink, Marc G., Abu Hilal, Mohammad, Manzoni, Alberto, Guerra, Martina, Daams, Freek, Kazemier, Geert, Izrailov, Roman, Efanov, Mikhail, Napoli, Niccolò, Ginesini, Michael, Cappelle, Marie, Haen, Roel, Quetel, Romain, and Pucci, Marco
- Abstract
Background: The use of robot-assisted and laparoscopic pancreatoduodenectomy is increasing, yet large adjusted analyses that can be generalized internationally are lacking. This study aimed to compare outcomes after robot-assisted pancreatoduodenectomy and laparoscopic pancreatoduodenectomy in a pan-European cohort. Methods: An international multicenter retrospective study including patients after robot-assisted pancreatoduodenectomy and laparoscopic pancreatoduodenectomy from 50 centers in 12 European countries (2009–2020). Propensity score matching was performed in a 1:1 ratio. The primary outcome was major morbidity (Clavien–Dindo ≥III). Results: Among 2,082 patients undergoing minimally invasive pancreatoduodenectomy, 1,006 underwent robot-assisted pancreatoduodenectomy and 1,076 laparoscopic pancreatoduodenectomy. After matching 812 versus 812 patients, the rates of major morbidity (31.9% vs 29.6%; P = .347) and 30-day/in-hospital mortality (4.3% vs 4.6%; P = .904) did not differ significantly between robot-assisted pancreatoduodenectomy and laparoscopic pancreatoduodenectomy, respectively. Robot-assisted pancreatoduodenectomy was associated with a lower conversion rate (6.7% vs 18.0%; P < .001) and higher lymph node retrieval (16 vs 14; P = .003). Laparoscopic pancreatoduodenectomy was associated with shorter operation time (446 minutes versus 400 minutes; P < .001), and lower rates of postoperative pancreatic fistula grade B/C (19.0% vs 11.7%; P < .001), delayed gastric emptying grade B/C (21.4% vs 7.4%; P < .001), and a higher R0-resection rate (73.2% vs 84.4%; P < .001). Conclusion: This European multicenter study found no differences in overall major morbidity and 30-day/in-hospital mortality after robot-assisted pancreatoduodenectomy compared with laparoscopic pancreatoduodenectomy. Further, laparoscopic pancreatoduodenectomy was associated with a lower rate of
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- 2024
19. Outcomes of a Multicenter Training Program in Robotic Pancreatoduodenectomy (LAELAPS-3)
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Zwart, Maurice J. W., Nota, Carolijn L. M., de Rooij, Thijs, van Hilst, Jony, te Riele, Wouter W., van Santvoort, Hjalmar C., Hagendoorn, Jeroen, Rinkes, Inne H. M. Borel, van Dam, Jacob L., Latenstein, Anouk E. J., Takagi, Kosei, Tran, T. C. Khé, Schreinemakers, Jennifer, van der Schelling, George, Wijsman, Jan H., Festen, Sebastiaan, Daams, Freek, Luyer, Misha D., de Hingh, Ignace H. J. T., Mieog, J. Sven D., Bonsing, Bert A., Lips, Daan J., Hilal, Mohammed Abu, Busch, Olivier R., Saint-Marc, Olivier, Zeh, Herbert J., III, Zureikat, Amer H., Hogg, Melissa E., Molenaar, I. Quintus, Besselink, Marc G., and Koerkamp, Bas Groot
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- 2021
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20. Updated Alternative Fistula Risk Score (ua-FRS) to Include Minimally Invasive Pancreatoduodenectomy: Pan-European Validation
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Mungroop, Timothy H., Klompmaker, Sjors, Wellner, Ulrich F., Steyerberg, Ewout W., Coratti, Andrea, D’Hondt, Mathieu, de Pastena, Matteo, Dokmak, Safi, Khatov, Igor, Saint-Marc, Olivier, Wittel, Uwe, Abu Hilal, Mohammed, Fuks, David, Poves, Ignasi, Keck, Tobias, Boggi, Ugo, and Besselink, Marc G.
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- 2021
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21. Implementation and outcome of minimally invasive pancreatoduodenectomy in Europe: a registry-based retrospective study - a critical appraisal of the first 3 years of the E-MIPS registry.
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Emmen, Anouk M. L. H., de Graaf, Nine, Khatkov, I. E., Busch, O. R., Dokmak, S., Boggi, Ugo, Koerkamp, Bas Groot, Ferrari, Giovanni, Molenaar, I. Q., Saint-Marc, Olivier, Ramera, Marco, Lips, Daan J., Mieog, J. S. D., Luyer, Misha D. P., Keck, Tobias, D'Hondt, Mathieu, Souche, F. R., Edwin, Bjørn, Hackert, Thilo, and Liem, M. S. L.
- Abstract
Background: International multicenter audit-based studies focusing on the outcome of minimally invasive pancreatoduodenectomy (MIPD) are lacking. The European Registry for Minimally Invasive Pancreatic Surgery (E-MIPS) is the E-AHPBA endorsed registry aimed to monitor and safeguard the introduction of MIPD in Europe. Materials and Methods: A planned analysis of outcomes among consecutive patients after MIPD from 45 centers in 14 European countries in the E-MIPS registry (2019-2021). The main outcomes of interest were major morbidity (Clavien-Dindo grade = 3) and 30-day/in-hospital mortality. Results: Overall, 1336 patients after MIPD were included [835 robot-assisted (R-MIPD) and 501 laparoscopic MIPD (L-MIPD)]. Overall, 20 centers performed R-MIPD, 15 centers L-MIPD, and 10 centers both. Between 2019 and 2021, the rate of centers performing L-MIPD decreased from 46.9 to 25%, whereas for R-MIPD this increased from 46.9 to 65.6%. Overall, the rate of major morbidity was 41.2%, 30-day/in-hospital mortality 4.5%, conversion rate 9.7%, postoperative pancreatic fistula grade B/C 22.7%, and postpancreatectomy hemorrhage grade B/C 10.8%. Median length of hospital stay was 12 days (IQR 8-21). A lower rate of major morbidity, postoperative pancreatic fistula grade B/C, postpancreatectomy hemorrhage grade B/C, delayed gastric emptying grade B/C, percutaneous drainage, and readmission was found after L-MIPD. The number of centers meeting the Miami Guidelines volume cut-off of =20 MIPDs annually increased from 9 (28.1%) in 2019 to 12 (37.5%) in 2021 (P=0.424). Rates of conversion (7.4 vs. 14.8% P <0.001) and reoperation (8.9 vs. 15.1% P <0.001) were lower in centers, which fulfilled the Miami volume cut-off. Conclusion: During the first 3 years of the pan-European E-MIPS registry, morbidity and mortality rates after MIPD were acceptable. A shift is ongoing from L-MIPD to R-MIPD. Variations in outcomes between the two minimally invasive approaches and the impact of the volume cut-off should be further evaluated over a longer time period. [ABSTRACT FROM AUTHOR]
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- 2024
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22. Updated Alternative Fistula Risk Score (ua-FRS) to Include Minimally Invasive Pancreatoduodenectomy: Pan-European Validation
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Mungroop, Timothy H., Klompmaker, Sjors, Wellner, Ulrich F., Steyerberg, Ewout W., Coratti, Andrea, D’Hondt, Mathieu, de Pastena, Matteo, Dokmak, Safi, Khatov, Igor, Saint-Marc, Olivier, Wittel, Uwe, Abu Hilal, Mohammed, Fuks, David, Poves, Ignasi, Keck, Tobias, Boggi, Ugo, and Besselink, Marc G.
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- 2019
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23. Outcomes After Minimally-invasive Versus Open Pancreatoduodenectomy: A Pan-European Propensity Score Matched Study
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Klompmaker, Sjors, van Hilst, Jony, Wellner, Ulrich F., Busch, Olivier R., Coratti, Andrea, D’Hondt, Mathieu, Dokmak, Safi, Festen, Sebastiaan, Kerem, Mustafa, Khatkov, Igor, Lips, Daan J., Lombardo, Carlo, Luyer, Misha, Manzoni, Alberto, Molenaar, Izaäk Q., Rosso, Edoardo, Saint-Marc, Olivier, Vansteenkiste, Franky, Wittel, Uwe A., Bonsing, Bert, Groot Koerkamp, Bas, Abu Hilal, Mohammed, Fuks, David, Poves, Ignasi, Keck, Tobias, Boggi, Ugo, and Besselink, Marc G.
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- 2018
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24. The Feasibility, Proficiency, and Mastery Learning Curves in 635 Robotic Pancreatoduodenectomies Following A Multicenter Training Program: 'Standing on the Shoulders of Giants'
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Zwart, Maurice J W, van den Broek, Bram, de Graaf, Nine, Suurmeijer, J Annelie, Augustinus, Simone, Te Riele, Wouter W, van Santvoort, Hjalmar C, Hagendoorn, Jeroen, Borel Rinkes, Inne H M, van Dam, Jacob L, Takagi, Kosei, Tran, T C Khé, Schreinemakers, Jennifer, van der Schelling, George, Wijsman, Jan H, de Wilde, Roeland F, Festen, Sebastiaan, Daams, Freek, Luyer, Misha D, de Hingh, Ignace H J T, Mieog, J Sven D, Bonsing, Bert A, Lips, Daan J, Hilal, M Abu, Busch, Olivier R, Saint-Marc, Olivier, Zeh, Herbert J, Zureikat, Amer H, Hogg, Melissa E, Koerkamp, Bas Groot, Molenaar, I Quintus, Besselink, Marc G, Zwart, Maurice J W, van den Broek, Bram, de Graaf, Nine, Suurmeijer, J Annelie, Augustinus, Simone, Te Riele, Wouter W, van Santvoort, Hjalmar C, Hagendoorn, Jeroen, Borel Rinkes, Inne H M, van Dam, Jacob L, Takagi, Kosei, Tran, T C Khé, Schreinemakers, Jennifer, van der Schelling, George, Wijsman, Jan H, de Wilde, Roeland F, Festen, Sebastiaan, Daams, Freek, Luyer, Misha D, de Hingh, Ignace H J T, Mieog, J Sven D, Bonsing, Bert A, Lips, Daan J, Hilal, M Abu, Busch, Olivier R, Saint-Marc, Olivier, Zeh, Herbert J, Zureikat, Amer H, Hogg, Melissa E, Koerkamp, Bas Groot, Molenaar, I Quintus, and Besselink, Marc G
- Abstract
OBJECTIVE: To assess the feasibility, proficiency, and mastery learning curves for robotic pancreatoduodenectomy (RPD) in "second-generation" RPD centers following a multicenter training program adhering to the IDEAL framework. BACKGROUND: The long learning curves for RPD reported from "pioneering" expert centers may discourage centers interested in starting an RPD program. However, the feasibility, proficiency, and mastery learning curves may be shorter in "second-generation" centers that participated in dedicated RPD training programs, although data are lacking. We report on the learning curves for RPD in "second-generation" centers trained in a dedicated nationwide program. METHODS: Post hoc analysis of all consecutive patients undergoing RPD in 7 centers that participated in the LAELAPS-3 training program, each with a minimum annual volume of 50 pancreatoduodenectomies, using the mandatory Dutch Pancreatic Cancer Audit (March 2016-December 2021). Cumulative sum analysis determined cutoffs for the 3 learning curves: operative time for the feasibility (1) risk-adjusted major complication (Clavien-Dindo grade ≥III) for the proficiency, (2) and textbook outcome for the mastery, (3) learning curve. Outcomes before and after the cutoffs were compared for the proficiency and mastery learning curves. A survey was used to assess changes in practice and the most valued "lessons learned." RESULTS: Overall, 635 RPD were performed by 17 trained surgeons, with a conversion rate of 6.6% (n=42). The median annual volume of RPD per center was 22.5±6.8. From 2016 to 2021, the nationwide annual use of RPD increased from 0% to 23% whereas the use of laparoscopic pancreatoduodenectomy decreased from 15% to 0%. The rate of major complications was 36.9% (n=234), surgical site infection 6.3% (n=40), postoperative pancreatic fistula (grade B/C) 26.9% (n=171), and 30-day/in-hospital mortality 3.5% (n=22). Cutoffs for the feasibility, proficiency, and mastery learning curves were reach
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- 2023
25. Robotic Distal Pancreatectomy, a Novel Standard of Care?:Benchmark Values for Surgical Outcomes from 16 International Expert Centers
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Müller, Philip C, Breuer, Eva, Nickel, Felix, Zani, Sabino, Kauffmann, Emanuele, De Franco, Lorenzo, Tschuor, Christoph, Suno Krohn, Paul, Burgdorf, Stefan K, Jonas, Jan Philipp, Oberkofler, Christian E, Petrowsky, Henrik, Saint-Marc, Olivier, Seelen, Leonard, Molenaar, Izaak Quintus, Wellner, Ulrich, Keck, Tobias, Coratti, Andrea, van Dam, Coen, de Wilde, Roeland, Koerkamp, Bas Groot, Valle, Valentina, Giulianotti, Pier, Ghabi, Elie, Moskal, David, Lavu, Harish, Vrochides, Dionisios, Martinie, John, Yeo, Charles, Sánchez-Velázquez, Patricia, Ielpo, Benedetto, Ajay, Pranay S, Shah, Mihir M, Kooby, David A, Gao, Song, Hao, Jihui, He, Jin, Boggi, Ugo, Hackert, Thilo, Allen, Peter, Borel-Rinkes, Inne H M, Clavien, Pierre Alain, Müller, Philip C, Breuer, Eva, Nickel, Felix, Zani, Sabino, Kauffmann, Emanuele, De Franco, Lorenzo, Tschuor, Christoph, Suno Krohn, Paul, Burgdorf, Stefan K, Jonas, Jan Philipp, Oberkofler, Christian E, Petrowsky, Henrik, Saint-Marc, Olivier, Seelen, Leonard, Molenaar, Izaak Quintus, Wellner, Ulrich, Keck, Tobias, Coratti, Andrea, van Dam, Coen, de Wilde, Roeland, Koerkamp, Bas Groot, Valle, Valentina, Giulianotti, Pier, Ghabi, Elie, Moskal, David, Lavu, Harish, Vrochides, Dionisios, Martinie, John, Yeo, Charles, Sánchez-Velázquez, Patricia, Ielpo, Benedetto, Ajay, Pranay S, Shah, Mihir M, Kooby, David A, Gao, Song, Hao, Jihui, He, Jin, Boggi, Ugo, Hackert, Thilo, Allen, Peter, Borel-Rinkes, Inne H M, and Clavien, Pierre Alain
- Abstract
Background and Objective: Robotic distal pancreatectomy (DP) is an emerging attractive approach, but its role compared with laparoscopic or open surgery remains unclear. Benchmark values are novel and objective tools for such comparisons. The aim of this study was to identify benchmark cutoffs for many outcome parameters for DP with or without splenectomy beyond the learning curve. Methods: This study analyzed outcomes from international expert centers from patients undergoing robotic DP for malignant or benign lesions. After excluding the first 10 cases in each center to reduce the effect of the learning curve, consecutive patients were included from the start of robotic DP up to June 2020. Benchmark patients had no significant comorbidities. Benchmark cutoff values were derived from the 75th or the 25th percentile of the median values of all benchmark centers. Benchmark values were compared with a laparoscopic control group from 4 high-volume centers and published open DP landmark series. Results: Sixteen centers contributed 755 cases, whereof 345 benchmark patients (46%) were included the analysis. Benchmark cutoffs included: operation time ≤300 minutes, conversion rate ≤3%, clinically relevant postoperative pancreatic fistula ≤32%, 3 months major complication rate ≤26.7%, and lymph node retrieval ≥9. The comprehensive complication index at 3 months was ≤8.7 without deterioration thereafter. Compared with robotic DP, laparoscopy had significantly higher conversion rates (5×) and overall complications, while open DP was associated with more blood loss and longer hospital stay. Conclusion: This first benchmark study demonstrates that robotic DP provides superior postoperative outcomes compared with laparoscopic and open DP. Robotic DP may be expected to become the approach of choice in minimally invasive DP.
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- 2023
26. The PD-ROBOSCORE:A difficulty score for robotic pancreatoduodenectomy
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Napoli, Niccolò, Cacace, Concetta, Kauffmann, Emanuele F., Jones, Leia, Ginesini, Michael, Gianfaldoni, Cesare, Salamone, Alice, Asta, Fabio, Ripolli, Allegra, Di Dato, Armando, Busch, Olivier R., Cappelle, Marie L., Chao, Ying Jui, de Wilde, Roeland F., Hackert, Thilo, Jang, Jin Young, Koerkamp, Bas Groot, Kwon, Wooil, Lips, Daan, Luyer, Misha D.P., Nickel, Felix, Saint-Marc, Olivier, Shan, Yan Shen, Shen, Baiyong, Vistoli, Fabio, Besselink, Marc G., Hilal, Mohammad Abu, Boggi, Ugo, Napoli, Niccolò, Cacace, Concetta, Kauffmann, Emanuele F., Jones, Leia, Ginesini, Michael, Gianfaldoni, Cesare, Salamone, Alice, Asta, Fabio, Ripolli, Allegra, Di Dato, Armando, Busch, Olivier R., Cappelle, Marie L., Chao, Ying Jui, de Wilde, Roeland F., Hackert, Thilo, Jang, Jin Young, Koerkamp, Bas Groot, Kwon, Wooil, Lips, Daan, Luyer, Misha D.P., Nickel, Felix, Saint-Marc, Olivier, Shan, Yan Shen, Shen, Baiyong, Vistoli, Fabio, Besselink, Marc G., Hilal, Mohammad Abu, and Boggi, Ugo
- Abstract
Background: Difficulty scoring systems are important for the safe, stepwise implementation of new procedures. We designed a retrospective observational study for building a difficulty score for robotic pancreatoduodenectomy. Methods: The difficulty score (PD-ROBOSCORE) aims at predicting severe postoperative complications after robotic pancreatoduodenectomy. The PD-ROBOSCORE was developed in a training cohort of 198 robotic pancreatoduodenectomies and was validated in an international multicenter cohort of 686 robotic pancreatoduodenectomies. Finally, all centers tested the model during the early learning curve (n = 300). Growing difficulty levels (low, intermediate, high) were defined using cut-off values set at the 33rd and 66th percentile (NCT04662346). Results: Factors included in the final multivariate model were a body mass index of ≥25 kg/m2 for males and ≥30 kg/m2 for females (odds ratio:2.39; P < .0001), borderline resectable tumor (odd ratio:1.98; P < .0001), uncinate process tumor (odds ratio:1.69; P < .0001), pancreatic duct size <4 mm (odds ratio:1.59; P < .0001), American Society of Anesthesiologists class ≥3 (odds ratio:1.59; P < .0001), and hepatic artery originating from the superior mesenteric artery (odds ratio:1.43; P < .0001). In the training cohort, the absolute score value (odds ratio = 1.13; P = .0089) and difficulty groups (odds ratio = 2.35; P = .041) predicted severe postoperative complications. In the multicenter validation cohort, the absolute score value predicted severe postoperative complications (odds ratio = 1.16, P < .001), whereas the difficulty groups did not (odds ratio = 1.94, P = .082). In the learning curve cohort, both absolute score value (odds ratio:1.078, P = .04) and difficulty groups (odds ratio: 2.25, P = .017) predicted severe postoperative complications. Across all cohorts, a PD-ROBOSCORE of ≥12.51 doubled the risk of severe postoperative complications. The PD-ROBOSCOR
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- 2023
27. The Feasibility, Proficiency, and Mastery Learning Curves in 635 Robotic Pancreatoduodenectomies Following a Multicenter Training Program: 'standing on the Shoulders of Giants'
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CTC, MS CGO, MS HOD, Cancer, Regenerative Medicine and Stem Cells, Zwart, Maurice J.W., Van Den Broek, Bram, De Graaf, Nine, Suurmeijer, José A., Augustinus, Simone, Te Riele, Wouter W., Van Santvoort, Hjalmar C., Hagendoorn, Jeroen, Borel Rinkes, Inne H.M., Van Dam, Jacob L., Takagi, Kosei, Tran, Khé T.C., Schreinemakers, Jennifer, Van Der Schelling, George, Wijsman, Jan H., De Wilde, Roeland F., Festen, Sebastiaan, Daams, Freek, Luyer, Misha D., De Hingh, Ignace H.J.T., Mieog, Jan S.D., Bonsing, Bert A., Lips, Daan J., Abu Hilal, Mohamed, Busch, Olivier R., Saint-Marc, Olivier, Zeh, Herbert J., Zureikat, Amer H., Hogg, Melissa E., Koerkamp, Bas G., Molenaar, Isaac Q., Besselink, Marc G., CTC, MS CGO, MS HOD, Cancer, Regenerative Medicine and Stem Cells, Zwart, Maurice J.W., Van Den Broek, Bram, De Graaf, Nine, Suurmeijer, José A., Augustinus, Simone, Te Riele, Wouter W., Van Santvoort, Hjalmar C., Hagendoorn, Jeroen, Borel Rinkes, Inne H.M., Van Dam, Jacob L., Takagi, Kosei, Tran, Khé T.C., Schreinemakers, Jennifer, Van Der Schelling, George, Wijsman, Jan H., De Wilde, Roeland F., Festen, Sebastiaan, Daams, Freek, Luyer, Misha D., De Hingh, Ignace H.J.T., Mieog, Jan S.D., Bonsing, Bert A., Lips, Daan J., Abu Hilal, Mohamed, Busch, Olivier R., Saint-Marc, Olivier, Zeh, Herbert J., Zureikat, Amer H., Hogg, Melissa E., Koerkamp, Bas G., Molenaar, Isaac Q., and Besselink, Marc G.
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- 2023
28. Robotic Distal Pancreatectomy, a Novel Standard of Care?: Benchmark Values for Surgical Outcomes from 16 International Expert Centers
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Cancer, MS CGO, Regenerative Medicine and Stem Cells, Müller, Philip C, Breuer, Eva, Nickel, Felix, Zani, Sabino, Kauffmann, Emanuele, De Franco, Lorenzo, Tschuor, Christoph, Suno Krohn, Paul, Burgdorf, Stefan K, Jonas, Jan Philipp, Oberkofler, Christian E, Petrowsky, Henrik, Saint-Marc, Olivier, Seelen, Leonard, Molenaar, Izaak Quintus, Wellner, Ulrich, Keck, Tobias, Coratti, Andrea, van Dam, Coen, de Wilde, Roeland, Koerkamp, Bas Groot, Valle, Valentina, Giulianotti, Pier, Ghabi, Elie, Moskal, David, Lavu, Harish, Vrochides, Dionisios, Martinie, John, Yeo, Charles, Sánchez-Velázquez, Patricia, Ielpo, Benedetto, Ajay, Pranay S, Shah, Mihir M, Kooby, David A, Gao, Song, Hao, Jihui, He, Jin, Boggi, Ugo, Hackert, Thilo, Allen, Peter, Borel-Rinkes, Inne H M, Clavien, Pierre Alain, Cancer, MS CGO, Regenerative Medicine and Stem Cells, Müller, Philip C, Breuer, Eva, Nickel, Felix, Zani, Sabino, Kauffmann, Emanuele, De Franco, Lorenzo, Tschuor, Christoph, Suno Krohn, Paul, Burgdorf, Stefan K, Jonas, Jan Philipp, Oberkofler, Christian E, Petrowsky, Henrik, Saint-Marc, Olivier, Seelen, Leonard, Molenaar, Izaak Quintus, Wellner, Ulrich, Keck, Tobias, Coratti, Andrea, van Dam, Coen, de Wilde, Roeland, Koerkamp, Bas Groot, Valle, Valentina, Giulianotti, Pier, Ghabi, Elie, Moskal, David, Lavu, Harish, Vrochides, Dionisios, Martinie, John, Yeo, Charles, Sánchez-Velázquez, Patricia, Ielpo, Benedetto, Ajay, Pranay S, Shah, Mihir M, Kooby, David A, Gao, Song, Hao, Jihui, He, Jin, Boggi, Ugo, Hackert, Thilo, Allen, Peter, Borel-Rinkes, Inne H M, and Clavien, Pierre Alain
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- 2023
29. Robotic Distal Pancreatectomy:A Novel Standard of Care? Benchmark Values for Surgical Outcomes from 16 International Expert Centers
- Author
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Müller, Philip C., Breuer, Eva, Nickel, Felix, Zani, Sabino, Kauffmann, Emanuele, De Franco, Lorenzo, Tschuor, Christoph, Krohn, Paul Suno, Burgdorf, Stefan K., Jonas, Jan Philipp, Oberkofler, Christian E., Petrowsky, Henrik, Saint-Marc, Olivier, Seelen, Leonard, Molenaar, Izaak Quintus, Wellner, Ulrich, Keck, Tobias, Coratti, Andrea, Van Dam, Jacob L., De Wilde, Roeland, Koerkamp, Bas Groot, Valle, Valentina, Giulianotti, Pier, Ghabi, Elie, Moskal, David, Lavu, Harish, Vrochides, Dionisios, Martinie, John, Yeo, Charles, Sánchez-velázquez, Patricia, Ielpo, Benedetto, Ajay, Pranay S., Shah, Mihir M., Kooby, David A., Gao, Song, Hao, Jihui, He, Jin, Boggi, Ugo, Hackert, Thilo, Allen, Peter, Borel-rinkes, Inne H.m., Clavien, Pierre Alain, Müller, Philip C., Breuer, Eva, Nickel, Felix, Zani, Sabino, Kauffmann, Emanuele, De Franco, Lorenzo, Tschuor, Christoph, Krohn, Paul Suno, Burgdorf, Stefan K., Jonas, Jan Philipp, Oberkofler, Christian E., Petrowsky, Henrik, Saint-Marc, Olivier, Seelen, Leonard, Molenaar, Izaak Quintus, Wellner, Ulrich, Keck, Tobias, Coratti, Andrea, Van Dam, Jacob L., De Wilde, Roeland, Koerkamp, Bas Groot, Valle, Valentina, Giulianotti, Pier, Ghabi, Elie, Moskal, David, Lavu, Harish, Vrochides, Dionisios, Martinie, John, Yeo, Charles, Sánchez-velázquez, Patricia, Ielpo, Benedetto, Ajay, Pranay S., Shah, Mihir M., Kooby, David A., Gao, Song, Hao, Jihui, He, Jin, Boggi, Ugo, Hackert, Thilo, Allen, Peter, Borel-rinkes, Inne H.m., and Clavien, Pierre Alain
- Abstract
Background and Objective: Robotic distal pancreatectomy (DP) is an emerging attractive approach, but its role compared to laparoscopic or open surgery remains unclear. Benchmark values are novel and objective tools for such comparisons. The aim of this study was to identify benchmark cutoffs for many outcome parameters for DP with or without splenectomy beyond the learning curve. Methods: This study analyzed outcomes from international expert centers from patients undergoing robotic DP for malignant or benign lesions. After excluding the first 10 cases in each center to reduce the effect of the learning curve, consecutive patients were included from the start of robotic DP up to June 2020. Benchmark patients had no significant comorbidities. Benchmark cutoff values were derived from the 75th or the 25th percentile of the median values of all benchmark centers. Benchmark values were compared to a laparoscopic control group from four high-volume centers and published open DP landmark series. Results: Sixteen centers contributed 755 cases, whereof 345 benchmark patients (46%) were included the analysis. Benchmark cut-offs included: operation time ≤300min, conversion rate ≤3%, clinically relevant POPF ≤32%, 3 months major complication rate ≤26.7% and lymph node retrieval ≥9. The CCI® at 3 months was ≤8.7 without deterioration thereafter. Compared to robotic DP, laparoscopy had significantly higher conversion rates (5x) and overall complications, while open DP was associated with more blood loss and longer hospital stay. Conclusion: This first benchmark study demonstrates that robotic DP provides superior postoperative outcomes compared to laparoscopic and open DP. Robotic DP may be expected to become the approach of choice in minimally invasive DP.
- Published
- 2023
30. Parathyroid Autotransplantation During Thyroid Surgery: A Novel Technique Using a Cell Culture Nutrient Solution
- Author
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Famà, Fausto, Cicciù, Marco, Polito, Francesca, Cascio, Antonio, Gioffré-Florio, Maria, Piquard, Arnaud, Saint-Marc, Olivier, and Sindoni, Alessandro
- Published
- 2017
- Full Text
- View/download PDF
31. Use and outcome of minimally invasive pancreatic surgery in the European E-MIPS registry
- Author
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van der Heijde, Nicky, primary, Vissers, Frederique L., additional, Manzoni, Alberto, additional, Zimmitti, Giuseppe, additional, Balsells, Joaquim, additional, Berrevoet, Frederik, additional, Bjornsson, Bergthor, additional, van den Boezem, Peter, additional, Boggi, Ugo, additional, Bratlie, Svein O., additional, Burdio, Fernando, additional, Coratti, Andrea, additional, D'Hondt, Mathieu, additional, Del Pozo, Carlos D., additional, Dokmak, Safi, additional, Fara, Regis, additional, Can, Mehmet F., additional, Festen, Sebastiaan, additional, Forgione, Antonello, additional, Fristrup, Claus, additional, Gaujoux, Sebastien, additional, Koerkamp, Bas G., additional, Hackert, Thilo, additional, Khatkov, Igor E., additional, Keck, Tobias, additional, Seppänen, Hanna, additional, Lips, Daan, additional, Luyer, Misha, additional, Pittau, Gabriella, additional, Maglione, Manuel, additional, Molenaar, I.Q., additional, Pessaux, Patrick, additional, Roeyen, Geert, additional, Saint-Marc, Olivier, additional, Cabus, Santiago S., additional, van Santvoort, Hjalmar, additional, van der Schelling, George, additional, Martin, Mario S., additional, Souche, Francois-regis, additional, Suarez Muñoz, Miguel Á., additional, Marino, Marco V., additional, Besselink, Marc G., additional, Hilal, Mohammed A., additional, Vilhav, Caroline, additional, Hartman, Vera, additional, Kirkegård, Jakob, additional, Sergeant, Gregory, additional, Kleeff, Jörg, additional, Coolsen, Marielle, additional, Coppola, Roberto, additional, Pauletti, Bruno, additional, Mittermair, Christof, additional, Tingstedt, Bobby, additional, Erkan, Mert, additional, Tomazic, Ales, additional, and Korkolis, Dimitris, additional
- Published
- 2022
- Full Text
- View/download PDF
32. Robotic Distal Pancreatectomy, a Novel Standard of Care? Benchmark Values for Surgical Outcomes from 16 International Expert Centers
- Author
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Müller, Philip C., primary, Breuer, Eva, additional, Nickel, Felix, additional, Zani, Sabino, additional, Kauffmann, Emanuele, additional, De Franco, Lorenzo, additional, Tschuor, Christoph, additional, Suno Krohn, Paul, additional, Burgdorf, Stefan K., additional, Jonas, Jan Philipp, additional, Oberkofler, Christian E., additional, Petrowsky, Henrik, additional, Saint-Marc, Olivier, additional, Seelen, Leonard, additional, Molenaar, Izaak Quintus, additional, Wellner, Ulrich, additional, Keck, Tobias, additional, Coratti, Andrea, additional, van Dam, Coen, additional, de Wilde, Roeland, additional, Koerkamp, Bas Groot, additional, Valle, Valentina, additional, Giulianotti, Pier, additional, Ghabi, Elie, additional, Moskal, David, additional, Lavu, Harish, additional, Vrochides, Dionisios, additional, Martinie, John, additional, Yeo, Charles, additional, Sánchez-Velázquez, Patricia, additional, Ielpo, Benedetto, additional, Ajay, Pranay S., additional, Shah, Mihir M., additional, Kooby, David A., additional, Gao, Song, additional, Hao, Jihui, additional, He, Jin, additional, Boggi, Ugo, additional, Hackert, Thilo, additional, Allen, Peter, additional, Borel-Rinkes, Inne H.M., additional, and Clavien, Pierre Alain, additional
- Published
- 2022
- Full Text
- View/download PDF
33. Free Perforation
- Author
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Nordlinger, Bernard, Saint-Marc, Olivier, Michelassi, Fabrizio, editor, and Milsom, Jeffrey W., editor
- Published
- 1999
- Full Text
- View/download PDF
34. Robotic Distal Pancreatectomy, a Novel Standard of Care?:Benchmark Values for Surgical Outcomes from 16 International Expert Centers
- Author
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Müller, Philip C, Breuer, Eva, Nickel, Felix, Zani, Sabino, Kauffmann, Emanuele, De Franco, Lorenzo, Tschuor, Christoph, Suno Krohn, Paul, Burgdorf, Stefan K, Jonas, Jan Philipp, Oberkofler, Christian E, Petrowsky, Henrik, Saint-Marc, Olivier, Seelen, Leonard, Molenaar, Izaak Quintus, Wellner, Ulrich, Keck, Tobias, Coratti, Andrea, van Dam, Coen, de Wilde, Roeland, Koerkamp, Bas Groot, Valle, Valentina, Giulianotti, Pier, Ghabi, Elie, Moskal, David, Lavu, Harish, Vrochides, Dionisios, Martinie, John, Yeo, Charles, Sánchez-Velázquez, Patricia, Ielpo, Benedetto, Ajay, Pranay S, Shah, Mihir M, Kooby, David A, Gao, Song, Hao, Jihui, He, Jin, Boggi, Ugo, Hackert, Thilo, Allen, Peter, Borel-Rinkes, Inne H M, Clavien, Pierre Alain, Müller, Philip C, Breuer, Eva, Nickel, Felix, Zani, Sabino, Kauffmann, Emanuele, De Franco, Lorenzo, Tschuor, Christoph, Suno Krohn, Paul, Burgdorf, Stefan K, Jonas, Jan Philipp, Oberkofler, Christian E, Petrowsky, Henrik, Saint-Marc, Olivier, Seelen, Leonard, Molenaar, Izaak Quintus, Wellner, Ulrich, Keck, Tobias, Coratti, Andrea, van Dam, Coen, de Wilde, Roeland, Koerkamp, Bas Groot, Valle, Valentina, Giulianotti, Pier, Ghabi, Elie, Moskal, David, Lavu, Harish, Vrochides, Dionisios, Martinie, John, Yeo, Charles, Sánchez-Velázquez, Patricia, Ielpo, Benedetto, Ajay, Pranay S, Shah, Mihir M, Kooby, David A, Gao, Song, Hao, Jihui, He, Jin, Boggi, Ugo, Hackert, Thilo, Allen, Peter, Borel-Rinkes, Inne H M, and Clavien, Pierre Alain
- Abstract
BACKGROUND AND OBJECTIVE: Robotic distal pancreatectomy (DP) is an emerging attractive approach, but its role compared to laparoscopic or open surgery remains unclear. Benchmark values are novel and objective tools for such comparisons. The aim of this study was to identify benchmark cutoffs for many outcome parameters for DP with or without splenectomy beyond the learning curve.METHODS: This study analyzed outcomes from international expert centers from patients undergoing robotic DP for malignant or benign lesions. After excluding the first 10 cases in each center to reduce the effect of the learning curve, consecutive patients were included from the start of robotic DP up to June 2020. Benchmark patients had no significant comorbidities. Benchmark cutoff values were derived from the 75 th or the 25 th percentile of the median values of all benchmark centers. Benchmark values were compared to a laparoscopic control group from four high-volume centers and published open DP landmark series.RESULTS: Sixteen centers contributed 755 cases, whereof 345 benchmark patients (46%) were included the analysis. Benchmark cut-offs included: operation time ≤300min, conversion rate ≤3%, clinically relevant POPF ≤32%, 3 months major complication rate ≤26.7% and lymph node retrieval ≥9. The CCI ® at 3 months was ≤8.7 without deterioration thereafter. Compared to robotic DP, laparoscopy had significantly higher conversion rates (5x) and overall complications, while open DP was associated with more blood loss and longer hospital stay.CONCLUSION: This first benchmark study demonstrates that robotic DP provides superior postoperative outcomes compared to laparoscopic and open DP. Robotic DP may be expected to become the approach of choice in minimally invasive DP.
- Published
- 2022
35. Robotic Distal Pancreatectomy
- Author
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Müller, Philip C., Breuer, Eva, Nickel, Felix, Zani, Sabino, Kauffmann, Emanuele, De Franco, Lorenzo, Tschuor, Christoph, Krohn, Paul Suno, Burgdorf, Stefan K., Jonas, Jan Philipp, Oberkofler, Christian E., Petrowsky, Henrik, Saint-Marc, Olivier, Seelen, Leonard, Molenaar, Izaak Quintus, Wellner, Ulrich, Keck, Tobias, Coratti, Andrea, van Dam, Jacob L., de Wilde, Roeland, Koerkamp, Bas Groot, Valle, Valentina, Giulianotti, Pier, Ghabi, Elie, Moskal, David, Lavu, Harish, Vrochides, Dionisios, Martinie, John, Yeo, Charles, Sánchez-Velázquez, Patricia, Ielpo, Benedetto, Ajay, Pranay S., Shah, Mihir M., Kooby, David A., Gao, Song, Hao, Jihui, He, Jin, Boggi, Ugo, Hackert, Thilo, Allen, Peter, Borel-Rinkes, Inne H.M., and Clavien, Pierre Alain
- Published
- 2023
- Full Text
- View/download PDF
36. Short-stay hospitalisation for benign thyroid surgery: a prospective study
- Author
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Fama’, Fausto, Linard, Cecile, Patti, Rosalia, Berry, Miles G., Gioffre’-Florio, Maria, Piquard, Arnaud, and Saint-Marc, Olivier
- Published
- 2013
- Full Text
- View/download PDF
37. Minimally invasive versus open distal pancreatectomy for pancreatic ductal adenocarcinoma (DIPLOMA) : study protocol for a randomized controlled trial
- Author
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van Hilst, Jony, Korrel, Maarten, Lof, Sanne, de Rooij, Thijs, Vissers, Frederique, Al-Sarireh, Bilal, Alseidi, Adnan, Bateman, Adrian C., Björnsson, Bergthor, Boggi, Ugo, Bratlie, Svein Olav, Busch, Olivier, Butturini, Giovanni, Casadei, Riccardo, Dijk, Frederike, Dokmak, Safi, Edwin, Bjorn, van Eijck, Casper, Esposito, Alessandro, Fabre, Jean-Michel, Falconi, Massimo, Ferrari, Giovanni, Fuks, David, Koerkamp, Bas Groot, Hackert, Thilo, Keck, Tobias, Khatkov, Igor, de Kleine, Ruben, Kokkola, Arto, Kooby, David A., Lips, Daan, Luyer, Misha, Marudanayagam, Ravi, Menon, Krishna, Molenaar, Quintus, de Pastena, Matteo, Pietrabissa, Andrea, Rajak, Rushda, Rosso, Edoardo, Sanchez Velazquez, Patricia, Saint Marc, Olivier, Shah, Mihir, Soonawalla, Zahir, Tomazic, Ales, Verbeke, Caroline, Verheij, Joanne, White, Steven, Wilmink, Hanneke W., Zerbi, Alessandro, Dijkgraaf, Marcel G., Besselink, Marc G., Abu Hilal, Mohammad, van Hilst, Jony, Korrel, Maarten, Lof, Sanne, de Rooij, Thijs, Vissers, Frederique, Al-Sarireh, Bilal, Alseidi, Adnan, Bateman, Adrian C., Björnsson, Bergthor, Boggi, Ugo, Bratlie, Svein Olav, Busch, Olivier, Butturini, Giovanni, Casadei, Riccardo, Dijk, Frederike, Dokmak, Safi, Edwin, Bjorn, van Eijck, Casper, Esposito, Alessandro, Fabre, Jean-Michel, Falconi, Massimo, Ferrari, Giovanni, Fuks, David, Koerkamp, Bas Groot, Hackert, Thilo, Keck, Tobias, Khatkov, Igor, de Kleine, Ruben, Kokkola, Arto, Kooby, David A., Lips, Daan, Luyer, Misha, Marudanayagam, Ravi, Menon, Krishna, Molenaar, Quintus, de Pastena, Matteo, Pietrabissa, Andrea, Rajak, Rushda, Rosso, Edoardo, Sanchez Velazquez, Patricia, Saint Marc, Olivier, Shah, Mihir, Soonawalla, Zahir, Tomazic, Ales, Verbeke, Caroline, Verheij, Joanne, White, Steven, Wilmink, Hanneke W., Zerbi, Alessandro, Dijkgraaf, Marcel G., Besselink, Marc G., and Abu Hilal, Mohammad
- Abstract
Background: Recently, the first randomized trials comparing minimally invasive distal pancreatectomy (MIDP) with open distal pancreatectomy (ODP) for non-malignant and malignant disease showed a 2-day reduction in time to functional recovery after MIDP. However, for pancreatic ductal adenocarcinoma (PDAC), concerns have been raised regarding the oncologic safety (i.e., radical resection, lymph node retrieval, and survival) of MIDP, as compared to ODP. Therefore, a randomized controlled trial comparing MIDP and ODP in PDAC regarding oncological safety is warranted. We hypothesize that the microscopically radical resection (R0) rate is non-inferior for MIDP, as compared to ODP. Methods/design: DIPLOMA is an international randomized controlled, patient- and pathologist-blinded, non-inferiority trial performed in 38 pancreatic centers in Europe and the USA. A total of 258 patients with an indication for elective distal pancreatectomy with splenectomy because of proven or highly suspected PDAC of the pancreatic body or tail will be randomly allocated to MIDP (laparoscopic or robot-assisted) or ODP in a 1:1 ratio. The primary outcome is the microscopically radical resection margin (R0, distance tumor to pancreatic transection and posterior margin >= 1 mm), which is assessed using a standardized histopathology assessment protocol. The sample size is calculated with the following assumptions: 5% one-sided significance level (alpha), 80% power (1-beta), expected R0 rate in the open group of 58%, expected R0 resection rate in the minimally invasive group of 67%, and a non-inferiority margin of 7%. Secondary outcomes include time to functional recovery, operative outcomes (e.g., blood loss, operative time, and conversion to open surgery), other histopathology findings (e.g., lymph node retrieval, perineural- and lymphovascular invasion), postoperative outcomes (e.g., clinically relevant complications, hospital stay, and administration of adjuvant treatment), time and si, Funding Agencies|Covidien AG (Medtronic, Neuhausen am Rheinfall, Switzerland) [ISR2017-10928]
- Published
- 2021
- Full Text
- View/download PDF
38. Cystadénome séreux microkystique : une tumeur rare du pancréas. À propos de deux observations
- Author
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Legrand, Mélanie, Delalande, Flore, Blechet, Claire, Kerdraon, Rémy, Saint-Marc, Olivier, and Michenet, Patrick
- Published
- 2019
- Full Text
- View/download PDF
39. Outcomes After Minimally-invasive Versus Open Pancreatoduodenectomy
- Author
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Klompmaker, Sjors, primary, van Hilst, Jony, additional, Wellner, Ulrich F., additional, Busch, Olivier R., additional, Coratti, Andrea, additional, D’Hondt, Mathieu, additional, Dokmak, Safi, additional, Festen, Sebastiaan, additional, Kerem, Mustafa, additional, Khatkov, Igor, additional, Lips, Daan J., additional, Lombardo, Carlo, additional, Luyer, Misha, additional, Manzoni, Alberto, additional, Molenaar, Izaäk Q., additional, Rosso, Edoardo, additional, Saint-Marc, Olivier, additional, Vansteenkiste, Franky, additional, Wittel, Uwe A., additional, Bonsing, Bert, additional, Groot Koerkamp, Bas, additional, Abu Hilal, Mohammed, additional, Fuks, David, additional, Poves, Ignasi, additional, Keck, Tobias, additional, Boggi, Ugo, additional, and Besselink, Marc G., additional
- Published
- 2020
- Full Text
- View/download PDF
40. Metastatic Endocrine Tumors: Medical Treatment, Surgical Resection, or Liver Transplantation
- Author
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Dousset, Bertrand, Saint-Marc, Olivier, Pitre, Jol, Soubrane, Olivier, Houssin, Didier, and Chapuis, Yves
- Published
- 1996
- Full Text
- View/download PDF
41. Long-term seton drainage for high anal fistulas in Crohn's disease—A sphincter-saving operation?
- Author
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Faucheron, Jean-Luc, Saint-Marc, Olivier, Guibert, Lionel, and Parc, Rolland
- Published
- 1996
- Full Text
- View/download PDF
42. LigaSure vs Clamp-and-Tie Technique to Achieve Hemostasis in Total Thyroidectomy for Benign Multinodular Goiter: A Prospective Randomized Study
- Author
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Saint Marc, Olivier, Cogliandolo, Andrea, Piquard, Arnaud, Famà, Fausto, and Pidoto, Rocco Roberto
- Published
- 2007
43. Surgical management of ileosigmoid fistulas in Crohn's disease: Role of preoperative colonoscopy
- Author
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Saint-Marc, Olivier, Vaillant, Jean-Christophe, Frileux, Pascal, Balladur, Pierre, Tiret, Emmanuel, and Parc, Rolland
- Published
- 1995
- Full Text
- View/download PDF
44. Outcomes After Minimally-invasive Versus Open Pancreatoduodenectomy A Pan-European Propensity Score Matched Study
- Author
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MS CGO, Cancer, Klompmaker, Sjors, van Hilst, Jony, Wellner, Ulrich F., Busch, Olivier R., Coratti, Andrea, D'Hondt, Mathieu, Dokmak, Safi, Festen, Sebastiaan, Kerem, Mustafa, Khatkov, Igor, Lips, Daan J., Lombardo, Carlo, Luyer, Misha, Manzoni, Alberto, Molenaar, Izaak Q., Rosso, Edoardo, Saint-Marc, Olivier, Vansteenkiste, Franky, Wittel, Uwe A., Bonsing, Bert, Koerkamp, Bas Groot, Abu Hilal, Mohammed, Fuks, David, Poves, Ignasi, Keck, Tobias, Boggi, Ugo, Besselink, Marc G., MS CGO, Cancer, Klompmaker, Sjors, van Hilst, Jony, Wellner, Ulrich F., Busch, Olivier R., Coratti, Andrea, D'Hondt, Mathieu, Dokmak, Safi, Festen, Sebastiaan, Kerem, Mustafa, Khatkov, Igor, Lips, Daan J., Lombardo, Carlo, Luyer, Misha, Manzoni, Alberto, Molenaar, Izaak Q., Rosso, Edoardo, Saint-Marc, Olivier, Vansteenkiste, Franky, Wittel, Uwe A., Bonsing, Bert, Koerkamp, Bas Groot, Abu Hilal, Mohammed, Fuks, David, Poves, Ignasi, Keck, Tobias, Boggi, Ugo, and Besselink, Marc G.
- Published
- 2020
45. Prospective evaluation of ultrasonography plus MIBI scintigraphy in selecting patients with primary hyperparathyroidism for unilateral neck exploration under local anaesthesia
- Author
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Saint Marc, Olivier, Cogliandolo, Andrea, Pidoto, Rocco Roberto, and Pozzo, Alessandro
- Published
- 2004
- Full Text
- View/download PDF
46. Análisis de situación, propuesta e implementación de mejoras en la gestión de un almacén de material de no producción de la planta de Almussafes de Ford España S.L
- Author
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Saint-Marc, Olivier Jean Baptiste
- Subjects
Almacén ,Digitalization ,Gestión ,Warehouse ,Management ,Organización ,Máster Universitario en Ingeniería Industrial-Màster Universitari en Enginyeria Industrial ,Automoción ,Automobile ,Digitalización ,Improvement ,ORGANIZACION DE EMPRESAS ,Agilización ,Organization - Abstract
[ES] El presente Trabajo de fin de Máster pretende agilizar la gestión de un almacén de material de no producción de la planta de Almussafes de Ford S.L. mediante unas implementaciones de mejora. Para entender las necesidades actuales del departamento de la empresa, se describirá el entorno de este ultimo y se analizará su situación actual. Tras realizar este análisis, se estudiarán las incidencias, sus causas y las potenciales medidas que se podrían tomar para resolverlas. A continuación, después de realizar un análisis de datos, se crearán unas reglas de organización física del almacén. Luego, se propondrá un cambio del sistema de identificación del material en el almacén para asegurar el buen seguimiento del material a mejor precio. En fin, se desarrollará por una parte la lógica de funcionamiento de una aplicación de gestión de almacén, y por otra parte su ergonomía para asegurar un uso sencillo., [EN] The objective of this Master Thesis is improving the management of a non-production material warehouse at Ford España S.L. through the implementation of several measures. To reach this objective, the environment of the problem will be explained. The department and its current situation will be analyzed to identify the causes and potential solutions to the problem. Through a study of data, some rules will be proposed to physically reorder the warehouse. In addition to that, the identification system of the material will be changed to reduce its cost and improve its efficiency. Finally, an application will be designed to help the labor force in their daily operations in stock management. On the one hand, its logic will be developed in order to ensure the respect of all the requirements, and on the other hand, its design will be drawn to ensure an easy use of such an application., [CA] El present Treball de fi de Màster pretén agilitzar la gestió d’un magatzem de materials de producció de la planta d’Almussafes de Ford S.L. mitjançant unes implementacions de millora. Per a entendre les necessitats actuals del departament de l’empresa, es descriurà l’entorn d’aquest últim y s’analitzarà la seua situació actual. Després de realitzar aquest anàlisis, s'estudiaran les incidències, les seues causes i les potencials mesures que es podrien prendre per a resoldre-les. A continuació, després de realitzar una anàlisi de dades, es crearan unes regles d'organització física del magatzem. Després, es proposarà un canvi del sistema d'identificació del material en el magatzem per a assegurar el bon seguiment del material a millor preu. En fi, es desenvoluparà d'una banda la lògica de funcionament d'una aplicació de gestió de magatzem, i d'altra banda la seva ergonomia per a assegurar un ús senzill.
- Published
- 2019
47. Robot-Assisted Total Gastrectomy: Preliminary Evaluation
- Author
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Sindayigaya, Rémy, primary, Guizani, Marwen, additional, Thébault, Baudouin, additional, Dussart, David, additional, Abou Mrad Fricquegnon, Adel, additional, Piquard, Arnaud, additional, and Saint-Marc, Olivier, additional
- Published
- 2019
- Full Text
- View/download PDF
48. Análisis de situación, propuesta e implementación de mejoras en la gestión de un almacén de material de no producción de la planta de Almussafes de Ford España S.L
- Author
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Maheut, Julien Philippe Dominique, García Sabater, José Pedro, Universitat Politècnica de València. Departamento de Organización de Empresas - Departament d'Organització d'Empreses, Universitat Politècnica de València. Escuela Técnica Superior de Ingenieros Industriales - Escola Tècnica Superior d'Enginyers Industrials, Saint-Marc, Olivier Jean Baptiste, Maheut, Julien Philippe Dominique, García Sabater, José Pedro, Universitat Politècnica de València. Departamento de Organización de Empresas - Departament d'Organització d'Empreses, Universitat Politècnica de València. Escuela Técnica Superior de Ingenieros Industriales - Escola Tècnica Superior d'Enginyers Industrials, and Saint-Marc, Olivier Jean Baptiste
- Abstract
[ES] El presente Trabajo de fin de Máster pretende agilizar la gestión de un almacén de material de no producción de la planta de Almussafes de Ford S.L. mediante unas implementaciones de mejora. Para entender las necesidades actuales del departamento de la empresa, se describirá el entorno de este ultimo y se analizará su situación actual. Tras realizar este análisis, se estudiarán las incidencias, sus causas y las potenciales medidas que se podrían tomar para resolverlas. A continuación, después de realizar un análisis de datos, se crearán unas reglas de organización física del almacén. Luego, se propondrá un cambio del sistema de identificación del material en el almacén para asegurar el buen seguimiento del material a mejor precio. En fin, se desarrollará por una parte la lógica de funcionamiento de una aplicación de gestión de almacén, y por otra parte su ergonomía para asegurar un uso sencillo., [EN] The objective of this Master Thesis is improving the management of a non-production material warehouse at Ford España S.L. through the implementation of several measures. To reach this objective, the environment of the problem will be explained. The department and its current situation will be analyzed to identify the causes and potential solutions to the problem. Through a study of data, some rules will be proposed to physically reorder the warehouse. In addition to that, the identification system of the material will be changed to reduce its cost and improve its efficiency. Finally, an application will be designed to help the labor force in their daily operations in stock management. On the one hand, its logic will be developed in order to ensure the respect of all the requirements, and on the other hand, its design will be drawn to ensure an easy use of such an application., [CA] El present Treball de fi de Màster pretén agilitzar la gestió d’un magatzem de materials de producció de la planta d’Almussafes de Ford S.L. mitjançant unes implementacions de millora. Per a entendre les necessitats actuals del departament de l’empresa, es descriurà l’entorn d’aquest últim y s’analitzarà la seua situació actual. Després de realitzar aquest anàlisis, s'estudiaran les incidències, les seues causes i les potencials mesures que es podrien prendre per a resoldre-les. A continuació, després de realitzar una anàlisi de dades, es crearan unes regles d'organització física del magatzem. Després, es proposarà un canvi del sistema d'identificació del material en el magatzem per a assegurar el bon seguiment del material a millor preu. En fi, es desenvoluparà d'una banda la lògica de funcionament d'una aplicació de gestió de magatzem, i d'altra banda la seva ergonomia per a assegurar un ús senzill.
- Published
- 2019
49. A primary pancreatic carcinoid tumour with unusual clinical complaints: A case report
- Author
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Pozzo Alessandro, Cogliandolo Andrea, Saint-Marc Olivier, and Pidoto Rocco
- Subjects
Carcinoid ,Pancreas ,Surgery ,RD1-811 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Unless metastatic or compressing the pancreatic duct, carcinoid of the pancreas are asymptomatic showing normal levels of serotonine and its metabolites in plasma and urine, thus resulting in delayed diagnosis and a consequent poor prognosis. However, if resection is timely accomplished, no local recurrence might be encountered and a normal survival might be expected in the absence of metastatic disease. Case Presentation The reported case of pancreatic carcinoid tumour in a 62-year-old woman reporting only atypical symptoms consisting of intermittent epigastric pain and nausea. Urinary 5-hydroxyindolacetic acid levels were within normal limits and only a slight elevation of serum serotonine level was detected on admission. After tumour localisation with endoscopic ultrasonography, left splenopancreasectomy with splenic, celiac and hepatic lymphadenectomy was carried out. Conclusion The role of endoscopic ultrasonography in early detection and precise localisation of pancreatic carcinoids, as well as the role of somatostatin-receptor scintigraphy with 111Indium labelled pentreotide in excluding distant metastases, are confirmed. The radical resection with lymphadenectomy is recommended in order to have a precise histological examination and detect occult lymph node metastases.
- Published
- 2004
- Full Text
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50. Preoperatively undiagnosed papillary thyroid carcinoma in patients thyroidectomized for benign multinodular goiter
- Author
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Fama, Fausto, primary, Sindoni, Alessandro, additional, Cicciu, Marco, additional, Polito, Francesca, additional, Piquard, Arnaud, additional, Saint-Marc, Olivier, additional, Gioffre´-Florio, Maria, additional, and Benvenga, Salvatore, additional
- Published
- 2018
- Full Text
- View/download PDF
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