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15 results on '"Sakakibara, Ayaka"'

4. MO52-4 Examination of patient characteristics in breast cancer patients who underwent BRCA genetic testing, according to reason for taking the test

Author

Sakakibara, Ayaka, primary, Ishiguro, Hiroshi, additional, Oakabe, Midori, additional, Hata, Kiyoko, additional, Kojima, Manami, additional, Nakame, Ayako, additional, Fujimoto, Akihiro, additional, Ichinose, Yuki, additional, Nukui, Asami, additional, Asano, Aya, additional, Shimada, Hiroko, additional, Matsuura, Kazuo, additional, Osaki, Akihiko, additional, and Saeki, Toshiaki, additional

Published
2023
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5. Clinicopathological prognostic characteristics and long‑term outcomes of patients with breast cancer and collagen disorder in comparison to those without collagen disorder

Author

Matsuura, Kazuo, primary, Osaki, Akihiko, additional, Ichinose, Yuki, additional, Fujimoto, Akihiro, additional, Sakakibara, Ayaka, additional, Nukui, Asami, additional, Yokogawa, Hideki, additional, Shimada, Hiroko, additional, Asano, Aya, additional, Ohara, Masahiro, additional, Ishiguro, Hiroshi, additional, Takahashi, Takao, additional, and Saeki, Toshiaki, additional

Published
2023
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6. Correction to: Tumor budding and fibrotic focus—proposed grading system for tumor budding in invasive carcinoma no special type of the breast

Author

Hiratsuka, Miyuki, primary, Hasebe, Takahiro, additional, Ichinose, Yuki, additional, Sakakibara, Ayaka, additional, Fujimoto, Akihiro, additional, Wakui, Noriko, additional, Shibasaki, Satomi, additional, Hirasaki, Masataka, additional, Yasuda, Masanori, additional, Nukui, Akemi, additional, Shimada, Hiroko, additional, Yokogawa, Hideki, additional, Matsuura, Kazuo, additional, Hojo, Takashi, additional, Osaki, Akihiko, additional, and Saeki, Toshiaki, additional

Published
2022
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7. Vimentin‐positive invasive breast carcinoma of no special type: A breast carcinoma with lethal biological characteristics.

Author

Ichinose, Yuki, Hasebe, Takahiro, Hirasaki, Masataka, Sakakibara, Ayaka, Yokogawa, Hideki, Nukui, Asami, Hiratsuka, Miyuki, Fujimoto, Akihiro, Iso, Chihiro, Wakui, Noriko, Shibasaki, Satomi, Kamada, Koichi, Suzuki, Nobuyuki, Kamakura, Yasuo, Yasuda, Masanori, Aya, Asano, Shimada, Hiroko, Matsuura, Kazuo, Ishiguro, Hiroshi, and Osaki, Akihiko

Subjects
BREAST, RNA sequencing, GENE expression, CELLULAR aging, CARCINOMA, CELL proliferation
Abstract

Vimentin is a stable mesenchymal immunohistochemical marker and is widely recognized as a major marker of mesenchymal tumors. The purpose of the present study was to investigate if the vimentin expression status might serve as a significant predictor of outcomes in patients with invasive breast carcinoma of no special type (IBC‐NST) and to investigate, by comprehensive RNA sequencing analyses, the mechanisms involved in the heightened malignant potential of vimentin‐positive IBC‐NSTs. This study, conducted using the data of 855 patients with IBC‐NST, clearly identified vimentin expression status as a very important independent biological parameter for accurately predicting the outcomes in patients with IBC‐NST. RNA sequence analyses clearly demonstrated significant upregulation of coding RNAs known to be closely associated with cell proliferation or cellular senescence, and significant downregulation of coding RNAs known to be closely associated with transmembrane transport in vimentin‐positive IBC‐NSTs. We conclude that vimentin‐positive IBC‐NSTs show heightened malignant biological characteristics, possibly attributable to the upregulation of RNAs closely associated with proliferative activity and cellular senescence, and downregulation of RNAs closely associated with transmembrane transport in IBC‐NSTs. [ABSTRACT FROM AUTHOR]

Published
2023
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9. MO32-7 High ALC, low NLR and PLR are associated with longer OS in patients with metastatic breast cancer treated with eribulin

Author

Matsuura, Kazuo, primary, Osaki, Akihiko, additional, Nakame, Ayako, additional, Fujimoto, Akihiro, additional, Ichinose, Yuki, additional, Nukui, Asami, additional, Asano, Aya, additional, Shimada, Hiroko, additional, Sano, Hiroshi, additional, Kosaka, Yoshimasa, additional, Hasebe, Takahiro, additional, Sakakibara, Ayaka, additional, and Saeki, Toshiaki, additional

Published
2021
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