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2. Effect of the relationship between anaemia and systemic inflammation on the risk of incident tuberculosis and death in people with advanced HIV: a sub-analysis of the REMEMBER trial

Author

Araújo-Pereira, Mariana, Krishnan, Sonya, Salgame, Padmini, Manabe, Yukari C., Hosseinipour, Mina C., Bisson, Gregory, Severe, Damocles Patrice, Rouzier, Vanessa, Leong, Samantha, Mave, Vidya, Sawe, Fredrick Kipyego, Siika, Abraham M., Kanyama, Cecilia, Dadabhai, Sufia S., Lama, Javier R., Valencia-Huamani, Javier, Badal-Faesen, Sharlaa, Lalloo, Umesh Gangaram, Naidoo, Kogieleum, Mohapi, Lerato, Kityo, Cissy, Andrade, Bruno B., and Gupta, Amita

Published
2023
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6. Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations

Author

Sarathy, Jansy, Blanc, Landry, Alvarez-Cabrera, Nadine, O’Brien, Paul, Dias-Freedman, Isabela, Mina, Marizel, Zimmerman, Matthew, Kaya, Firat, Liang, Hsin-Pin Ho, Prideaux, Brendan, Dietzold, Jillian, Salgame, Padmini, Savic, Radojka M, Linderman, Jennifer, Kirschner, Denise, Pienaar, Elsje, and Dartois, Véronique

Subjects
Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Infectious Diseases, Prevention, Tuberculosis, Orphan Drug, Emerging Infectious Diseases, Clinical Research, Biodefense, Clinical Trials and Supportive Activities, Vaccine Related, Antimicrobial Resistance, Rare Diseases, Infection, Good Health and Well Being, Animals, Antitubercular Agents, Fluoroquinolones, Levofloxacin, Microbial Sensitivity Tests, Moxifloxacin, Rabbits, Tandem Mass Spectrometry, Tuberculosis, Multidrug-Resistant, MDR-TB, fluoroquinolone, lesion-centric pharmacology, moxifloxacin, tuberculosis, Microbiology, Medical Microbiology, Medical microbiology, Pharmacology and pharmaceutical sciences
Abstract

Fluoroquinolones represent the pillar of multidrug-resistant tuberculosis (MDR-TB) treatment, with moxifloxacin, levofloxacin, or gatifloxacin being prescribed to MDR-TB patients. Recently, several clinical trials of "universal" drug regimens, aiming to treat drug-susceptible and drug-resistant TB, have included a fluoroquinolone. In the absence of clinical data comparing their side-by-side efficacies in controlled MDR-TB trials, a pharmacological rationale is needed to guide the selection of the most efficacious fluoroquinolone. The present studies were designed to test the hypothesis that fluoroquinolone concentrations (pharmacokinetics) and activity (pharmacodynamics) at the site of infection are better predictors of efficacy than the plasma concentrations and potency measured in standard growth inhibition assays and are better suited to determinations of whether one of the fluoroquinolones outperforms the others in rabbits with active TB. We first measured the penetration of these fluoroquinolones in lung lesion compartments, and their potency against bacterial populations that reside in each compartment, to compute lesion-centric pharmacokinetic-pharmacodynamic (PK/PD) parameters. PK modeling methods were used to quantify drug penetration from plasma to tissues at human-equivalent doses. On the basis of these metrics, moxifloxacin emerged with a clear advantage, whereas plasma-based PK/PD favored levofloxacin (the ranges of the plasma AUC/MIC ratio [i.e., the area under the concentration-time curve over 24 h in the steady state divided by the MIC] are 46 to 86 for moxifloxacin and 74 to 258 for levofloxacin). A comparative efficacy trial in the rabbit model of active TB demonstrated the superiority of moxifloxacin in reducing bacterial burden at the lesion level and in sterilizing cellular and necrotic lesions. Collectively, these results show that PK/PD data obtained at the site of infection represent an adequate predictor of drug efficacy against TB and constitute the baseline required to explore synergies, antagonism, and drug-drug interactions in fluoroquinolone-containing regimens.

Published
2019

14. Tuberculosis—Learning the Impact of Nutrition (TB LION): protocol for an interventional study to decrease TB risk in household contacts

Author

Cintron, Chelsie, Narasimhan, Prakash Babu, Locks, Lindsey, Babu, Senbagavalli, Sinha, Pranay, Rajkumari, Nonika, Kaipilyawar, Vaishnavi, Bhargava, Anurag, Maloomian, Kimberly, Chandrasekaran, Padma, Verma, Sheetal, Joseph, Noyal, Johnson, W. Evan, Wanke, Christine, Horsburgh, Jr., C. Robert, Ellner, Jerrold J., Sarkar, Sonali, Salgame, Padmini, Lakshminarayanan, Subitha, and Hochberg, Natasha S.

Published
2021
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15. High resolution imaging and five-year tuberculosis contact outcomes

Author

Esmail, Hanif, primary, Coussens, Anna K, additional, Thienemann, Friedrich, additional, Sossen, Bianca, additional, Mukasa, Sandra L, additional, Warwick, James, additional, Goliath, Rene T., additional, Davies, Nashreen Omar, additional, Douglass, Emily, additional, Jackson, Amanda, additional, Lakay, Francisco, additional, Streicher, Elizabeth, additional, Munro, Jacob E., additional, Barrios, Marilou H, additional, Heinsohn, Torben, additional, Macpherson, Liana, additional, Sheerin, Dylan, additional, Aziz, Saalikha, additional, Serole, Keboile, additional, Daroowala, Remy, additional, Taliep, Arshad, additional, Ahlers, Petri, additional, Malherbe, Stephanus T., additional, Bowden, Rory, additional, Warren, Robin, additional, Walzl, Gerhard, additional, Via, Laura E., additional, Bahlo, Melanie, additional, Jacobson, Karen R., additional, Horsburgh, C. Robert, additional, Salgame, Padmini, additional, Alland, David, additional, Barry, Clifton Earl, additional, Flynn, JoAnne L., additional, Ellner, Jerrold J, additional, and Wilkinson, Robert J, additional

Published
2023
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19. Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis

Author

Gupta, Shamba, primary, Bhagavathula, Madhuri, additional, Sharma, Vartika, additional, Sharma, Nishant, additional, Sharma, Nevadita, additional, Biswas, Ashis, additional, Palacios, Ainhoa, additional, Salgueiro, Vivian, additional, Lavín, Jose L, additional, Dogra, Navneet, additional, Salgame, Padmini, additional, Prados‐Rosales, Rafael, additional, and Rodríguez, G Marcela, additional

Published
2023
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20. Strains of Mycobacterium tuberculosis transmitting infection in Brazilian households and those associated with community transmission of tuberculosis

Author

Vinhas, Solange Alves, Jones-López, Edward C., Ribeiro Rodrigues, Rodrigo, Gaeddert, Mary, Peres, Renata Lyrio, Marques-Rodrigues, Patricia, de Aguiar, Paola Poloni Lobo, White, Laura Forsberg, Alland, David, Salgame, Padmini, Hom, David, Ellner, Jerrold J., Dietze, Reynaldo, Collins, Lauren F., Shashkina, Elena, Kreiswirth, Barry, and Palaci, Moisés

Published
2017
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29. Predictors of weight loss during the intensive phase of tuberculosis treatment in patients with drug-susceptible pulmonary tuberculosis in South India.

Author

Kalva, Jayashree, Babu, Senbagavalli P, Narasimhan, Prakash B, Raghupathy, Kalaivani, Ezhumalai, Komala, Knudsen, Selby, Horsburgh, Charles R, Hochberg, Natasha, Salgame, Padmini, Roy, Gautam, Ellner, Jerrold, and Sarkar, Sonali

Subjects
WEIGHT loss -- Risk factors, SPUTUM microbiology, DRUG therapy for tuberculosis, STATISTICS, BODY weight, MULTIPLE regression analysis, MULTIVARIATE analysis, PEOPLE with alcoholism, RISK assessment, T-test (Statistics), WASTING syndrome, DESCRIPTIVE statistics, CHI-squared test, RESEARCH funding, DATA analysis software, ODDS ratio, LONGITUDINAL method, DISEASE risk factors
Abstract

Background Tuberculosis (TB) is well-known for causing wasting. Patients on treatment gain weight and weight loss is associated with unfavorable treatment outcomes. There is limited description of weight loss and its predictors during intensive treatment phase. The objective of this study was to assess the predictors of weight loss during intensive phase and to see if there is any association exists with sputum conversion at the end of intensive phase of treatment. Methods Data collected as a part of the prospective TB cohort (Regional Prospective Observational Research for TB India Phase 1) conducted in Pondicherry, Cuddalore and Viluppuram districts of Tamil Nadu were used for this study. Sputum smear and body weight comparison were made in the baseline and at the end of second month of treatment. Results In all, 726 participants had weight measurements at the two time points and 18.7% had weight loss; mean weight lost being 2.3 kg (SD 3.05). Mean weight loss was more among males (2.4 kg, SD 3.2), diabetics (2.8 kg, SD 3.9) and alcoholics (2.1 kg, SD 2.4). Alcohol consumption was the only predictor of weight loss after adjusting for age, diabetes, marital status and BMI (aRR 1.52, P 0.02). Weight loss was not associated with sputum conversion at the end of second month. Conclusions Alcohol use emerged as the major predictor for weight loss during intensive phase. [ABSTRACT FROM AUTHOR]

Published
2023
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31. Predictors of weight loss during the intensive phase of tuberculosis treatment in patients with drug-susceptible pulmonary tuberculosis in South India

Author

Kalva, Jayashree, primary, Babu, Senbagavalli P, additional, Narasimhan, Prakash B, additional, Raghupathy, Kalaivani, additional, Ezhumalai, Komala, additional, Knudsen, Selby, additional, Horsburgh, Charles R, additional, Hochberg, Natasha, additional, Salgame, Padmini, additional, Roy, Gautam, additional, Ellner, Jerrold, additional, and Sarkar, Sonali, additional

Published
2022
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32. Impact of Undernutrition on Tuberculosis Treatment Outcomes in India: A Multicenter, Prospective, Cohort Analysis

Author

Sinha, Pranay, primary, Ponnuraja, Chinnaiyan, additional, Gupte, Nikhil, additional, Babu, Senbagavalli Prakash, additional, Cox, Samyra R, additional, Sarkar, Sonali, additional, Mave, Vidya, additional, Paradkar, Mandar, additional, Cintron, Chelsie, additional, Govindarajan, S, additional, Kinikar, Aarti, additional, Priya, Nadesan, additional, Gaikwad, Sanjay, additional, Thangakunam, Balamugesh, additional, Devarajan, Arutselvi, additional, Dhanasekaran, Mythili, additional, Tornheim, Jeffrey A, additional, Gupta, Amita, additional, Salgame, Padmini, additional, Christopher, Devashyam Jesudas, additional, Kornfeld, Hardy, additional, Viswanathan, Vijay, additional, Ellner, Jerrold J, additional, Horsburgh, C Robert, additional, Gupte, Akshay N, additional, Padmapriyadarsini, Chandrasekaran, additional, and Hochberg, Natasha S, additional

Published
2022
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33. Diagnostic biomarkers for active tuberculosis: progress and challenges

Author

Nogueira, Betânia M F, primary, Krishnan, Sonya, additional, Barreto‐Duarte, Beatriz, additional, Araújo‐Pereira, Mariana, additional, Queiroz, Artur T L, additional, Ellner, Jerrold J, additional, Salgame, Padmini, additional, Scriba, Thomas J, additional, Sterling, Timothy R, additional, Gupta, Amita, additional, and Andrade, Bruno B, additional

Published
2022
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34. Corrigendum: Malnutrition leads to increased inflammation and expression of tuberculosis risk signatures in recently exposed household contacts of pulmonary tuberculosis

Author

VanValkenburg, Arthur, primary, Kaipilyawar, Vaishnavi, additional, Sarkar, Sonali, additional, Lakshminarayanan, Subitha, additional, Cintron, Chelsie, additional, Babu, Senbagavalli Prakash, additional, Knudsen, Selby, additional, Joseph, Noyal Mariya, additional, Horsburgh, C. Robert, additional, Sinha, Pranay, additional, Ellner, Jerrold J., additional, Narasimhan, Prakash Babu, additional, Johnson, William Evan, additional, Hochberg, Natasha S., additional, and Salgame, Padmini, additional

Published
2022
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36. Malnutrition leads to increased inflammation and expression of tuberculosis risk signatures in recently exposed household contacts of pulmonary tuberculosis

Author

VanValkenburg, Arthur, primary, Kaipilyawar, Vaishnavi, additional, Sarkar, Sonali, additional, Lakshminarayanan, Subitha, additional, Cintron, Chelsie, additional, Prakash Babu, Senbagavalli, additional, Knudsen, Selby, additional, Joseph, Noyal Mariya, additional, Horsburgh, C. Robert, additional, Sinha, Pranay, additional, Ellner, Jerrold J., additional, Narasimhan, Prakash Babu, additional, Johnson, W. Evan, additional, Hochberg, Natasha S., additional, and Salgame, Padmini, additional

Published
2022
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37. Development of prognostic scoring system for predicting 1-year mortality among pulmonary tuberculosis patients in South India

Author

Krishnamoorthy, Yuvaraj, primary, Ezhumalai, Komala, additional, Murali, Sharan, additional, Rajaa, Sathish, additional, Majella, Marie Gilbert, additional, Sarkar, Sonali, additional, Lakshminarayanan, Subitha, additional, Joseph, Noyal Mariya, additional, Soundappan, Govindarajan, additional, Prakash Babu, Senbagavalli, additional, Horsburgh, Charles, additional, Hochberg, Natasha, additional, Johnson, W Evan, additional, Knudsen, Selby, additional, Pentakota, Sri Ram, additional, Salgame, Padmini, additional, Roy, Gautam, additional, and Ellner, Jerrold, additional

Published
2022
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38. Development of prognostic scoring system for predicting 1-year mortality among pulmonary tuberculosis patients in South India.

Author

Krishnamoorthy, Yuvaraj, Ezhumalai, Komala, Murali, Sharan, Rajaa, Sathish, Majella, Marie Gilbert, Sarkar, Sonali, Lakshminarayanan, Subitha, Joseph, Noyal Mariya, Soundappan, Govindarajan, Babu, Senbagavalli Prakash, Horsburgh, Charles, Hochberg, Natasha, Johnson, W Evan, Knudsen, Selby, Pentakota, Sri Ram, Salgame, Padmini, Roy, Gautam, and Ellner, Jerrold

Subjects
TUBERCULOSIS treatment, EXPERIMENTAL design, CONFIDENCE intervals, LEUCOPENIA, RESEARCH methodology, INTERVIEWING, NEUTROPHILS, LYMPHOCYTES, ANEMIA, RESEARCH funding, DESCRIPTIVE statistics, PREDICTIVE validity, POLICY sciences, SOCIODEMOGRAPHIC factors, LONGITUDINAL method, PROBABILITY theory
Abstract

Background Development of a prediction model using baseline characteristics of tuberculosis (TB) patients at the time of diagnosis will aid us in early identification of the high-risk groups and devise pertinent strategies accordingly. Hence, we did this study to develop a prognostic-scoring model for predicting the death among newly diagnosed drug sensitive pulmonary TB patients in South India. Methods We undertook a longitudinal analysis of cohort data under the Regional Prospective Observational Research for Tuberculosis India consortium. Multivariable cox regression using the stepwise backward elimination procedure was used to select variables for the model building and the nomogram-scoring system was developed with the final selected model. Results In total, 54 (4.6%) out of the 1181 patients had died during the 1-year follow-up period. The TB mortality rate was 0.20 per 1000 person-days. Eight variables (age, gender, functional limitation, anemia, leukopenia, thrombocytopenia, diabetes, neutrophil–lymphocyte ratio) were selected and a nomogram was built using these variables. The discriminatory power was 0.81 (95% confidence interval: 0.75–0.86) and this model was well-calibrated. Decision curve analysis showed that the model is beneficial at a threshold probability ~15–65%. Conclusions This scoring system could help the clinicians and policy makers to devise targeted interventions and in turn reduce the TB mortality in India. [ABSTRACT FROM AUTHOR]

Published
2023
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39. Effect of treatment adherence on the association between sex and unfavourable treatment outcomes among tuberculosis patients in Puducherry, India: a mediation analysis.

Author

Barathi, Arivarasan, Krishnamoorthy, Yuvaraj, Sinha, Pranay, Horsburgh, Charles, Hochberg, Natasha, Johnson, Evan, Salgame, Padmini, Govindarajan, Soundappan, Senbagavalli, P B, Lakshinarayanan, Subitha, Roy, Gautam, Ellner, Jerrold, and Sarkar, Sonali

Subjects
TUBERCULOSIS mortality, DRUG therapy for tuberculosis, PARASITOLOGY, CONFIDENCE intervals, SPUTUM, SEX distribution, TREATMENT effectiveness, MICROBIOLOGICAL techniques, FACTOR analysis, RESEARCH funding, PATIENT compliance, BODY mass index, DRUG resistance in microorganisms, LOGISTIC regression analysis, ODDS ratio, LONGITUDINAL method, MICROBIAL sensitivity tests
Abstract

Background A better understanding of the complex interplay between risk factors of tuberculosis (TB) is essential. This study was part of the Regional Prospective Observational Research for Tuberculosis (RePORT) India consortium and includes newly diagnosed TB patients in Puducherry between 2014 and 2018. We employed mediation analysis to identify the effect of treatment adherence on association between sex and unfavourable TB treatment outcomes. Methods Required demographic and treatment-related variables were extracted from the RePORT India consortium database and causal mediation analysis using parametric regression models was done. Results Of the 712 TB patients, ~87 (12.2%) had unfavourable TB treatment outcomes. Total effect of male sex was significantly associated with the unfavourable TB treatment outcomes [adjusted odds ratio (aOR) = 2.48; 95% confidence interval (CI): 1.11–5.55]. However, the overall association between male sex and TB treatment outcomes was dominated by the indirect pathway, as the direct pathway does not show significant association (aOR = 1.67; 95% CI: 0.75–3.75), while the indirect pathway shows significantly higher odds of TB treatment outcomes (aOR = 1.48; 95% CI:1.27–1.73), indicating complete mediation by the treatment adherence. Conclusions The study has shown a complete mediation of sexes through TB treatment adherence for unfavourable treatment outcomes. Developing of treatment strategies require better understanding between the biological and social factors related to TB. [ABSTRACT FROM AUTHOR]

Published
2023
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40. Impact of Undernutrition on Tuberculosis Treatment Outcomes in India: A Multicenter, Prospective, Cohort Analysis.

Author

Sinha, Pranay, Ponnuraja, Chinnaiyan, Gupte, Nikhil, Babu, Senbagavalli Prakash, Cox, Samyra R, Sarkar, Sonali, Mave, Vidya, Paradkar, Mandar, Cintron, Chelsie, Govindarajan, S, Kinikar, Aarti, Priya, Nadesan, Gaikwad, Sanjay, Thangakunam, Balamugesh, Devarajan, Arutselvi, Dhanasekaran, Mythili, Tornheim, Jeffrey A, Gupta, Amita, Salgame, Padmini, and Christopher, Devashyam Jesudas

Subjects
TUBERCULOSIS treatment, RESEARCH, CONFIDENCE intervals, MULTIPLE regression analysis, TREATMENT effectiveness, MALNUTRITION, RESEARCH funding, BODY mass index, ODDS ratio, LONGITUDINAL method, POISSON distribution, DISEASE complications
Abstract

Background Undernutrition is the leading risk factor for tuberculosis (TB) globally. Its impact on treatment outcomes is poorly defined. Methods We conducted a prospective cohort analysis of adults with drug-sensitive pulmonary TB at 5 sites from 2015–2019. Using multivariable Poisson regression, we assessed associations between unfavorable outcomes and nutritional status based on body mass index (BMI) nutritional status at treatment initiation, BMI prior to TB disease, stunting, and stagnant or declining BMI after 2 months of TB treatment. Unfavorable outcome was defined as a composite of treatment failure, death, or relapse within 6 months of treatment completion. Results Severe undernutrition (BMI <16 kg/m2) at treatment initiation and severe undernutrition before the onset of TB disease were both associated with unfavorable outcomes (adjusted incidence rate ratio [aIRR], 2.05; 95% confidence interval [CI], 1.42–2.91 and aIRR, 2.20; 95% CI, 1.16–3.94, respectively). Additionally, lack of BMI increase after treatment initiation was associated with increased unfavorable outcomes (aIRR, 1.81; 95% CI, 1.27–2.61). Severe stunting (height-for-age z score <−3) was associated with unfavorable outcomes (aIRR, 1.52; 95% CI, 1.00–2.24). Severe undernutrition at treatment initiation and lack of BMI increase during treatment were associated with a 4- and 5-fold higher rate of death, respectively. Conclusions Premorbid undernutrition, undernutrition at treatment initiation, lack of BMI increase after intensive therapy, and severe stunting are associated with unfavorable TB treatment outcomes. These data highlight the need to address this widely prevalent TB comorbidity. Nutritional assessment should be integrated into standard TB care. [ABSTRACT FROM AUTHOR]

Published
2023
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42. Effect of treatment adherence on the association between sex and unfavourable treatment outcomes among tuberculosis patients in Puducherry, India: a mediation analysis

Author

Barathi, Arivarasan, primary, Krishnamoorthy, Yuvaraj, additional, Sinha, Pranay, additional, Horsburgh, Charles, additional, Hochberg, Natasha, additional, Johnson, Evan, additional, Salgame, Padmini, additional, Govindarajan, Soundappan, additional, Senbagavalli, P B, additional, Lakshinarayanan, Subitha, additional, Roy, Gautam, additional, Ellner, Jerrold, additional, and Sarkar, Sonali, additional

Published
2022
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43. Immunologic Biomarkers in Peripheral Blood of Persons With Tuberculosis and Advanced HIV

Author

Queiroz, Artur T. L., primary, Araújo-Pereira, Mariana, additional, Barreto-Duarte, Beatriz, additional, Gomes-Silva, Adriano, additional, Costa, Allyson G., additional, Andrade, Alice M. S., additional, Miguez-Pinto, João Pedro, additional, Spener-Gomes, Renata, additional, Souza, Alexandra B., additional, Benjamin, Aline, additional, Sant’Anna, Flavia, additional, Figueiredo, Marina C., additional, Mave, Vidya, additional, Salgame, Padmini, additional, Ellner, Jerrold J., additional, Sterling, Timothy R., additional, Cordeiro-dos-Santos, Marcelo, additional, Andrade, Bruno B., additional, and Rolla, Valeria C., additional

Published
2022
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44. Derivation of a parsimonious Tuberculosis gene signature using the digital NanoString nCounter platform.

Author

Kaipilyawar, Vaishnavi, primary, Zhao, Yue, additional, Wang, Xutao, additional, Joseph, Noyal M, additional, Babu, Senbagavalli Prakash, additional, Hochberg, Natasha S, additional, Sarkar, Sonali, additional, Horsburgh, Charles, additional, Ellner, Jerrold J, additional, Johnson, William Evan, additional, and Salgame, Padmini, additional

Published
2022
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45. Comparison of IGRA and TST in the diagnosis of latent tuberculosis among women of reproductive age in SOUTH India

Author

Babu, Senbagavalli Prakash, primary, Ezhumalai, Komala, additional, Raghupathy, Kalaivani, additional, Sundaresan, Madhusudanan, additional, Jain, Komal, additional, Narasimhan, Prakash Babu, additional, Knudsen, Selby, additional, Horsburgh, C. Robert, additional, Hochberg, Natasha S., additional, Salgame, Padmini, additional, Ellner, Jerrold, additional, and Sarkar, Sonali, additional

Published
2022
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46. Development and Validation of a Parsimonious Tuberculosis Gene Signature Using the digital NanoString nCounter Platform

Author

Kaipilyawar, Vaishnavi, primary, Zhao, Yue, additional, Wang, Xutao, additional, Joseph, Noyal M, additional, Knudsen, Selby, additional, Prakash Babu, Senbagavalli, additional, Muthaiah, Muthuraj, additional, Hochberg, Natasha S, additional, Sarkar, Sonali, additional, Horsburgh, Charles R, additional, Ellner, Jerrold J, additional, Johnson, W Evan, additional, and Salgame, Padmini, additional

Published
2022
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47. Impact of the Relationship between Anaemia and Systemic Inflammation on the Risk of Incident Tuberculosis and Death in Persons with Advanced HIV: A Sub-Analysis of the REMEMBER Trial

Author

Araújo-Pereira, Mariana, primary, Krishnan, Sonya, additional, Salgame, Padmini, additional, Manabe, Yukari, additional, Hosseinipour, Mina C., additional, Bisson, Gregory, additional, Severe, Damocles Patrice, additional, Rouzier, Vanessa, additional, Leong, Samantha, additional, Mave, Vidya, additional, Sawe, Fred, additional, Siika, Abraham M., additional, Kanyama, Cecilia, additional, Dadabhai, Sufia, additional, Lama, Javier, additional, Valencia-Huamani, Javier, additional, Badal-Faesen, Sharlaa, additional, Lallo, Umesh Gangaram, additional, Naidoo, Kogieleum, additional, Mohapi, Lerato, additional, Kityo, Cissy, additional, Andrade, Bruno B., additional, and Gupta, Amita, additional

Published
2022
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48. Prevalence and risk factors associated with latent tuberculosis infection among household contacts of smear positive pulmonary tuberculosis patients in South India

Author

Krishnamoorthy, Yuvaraj, primary, Ezhumalai, Komala, additional, Murali, Sharan, additional, Rajaa, Sathish, additional, Jose, Maria, additional, Sathishkumar, Abilasha, additional, Soundappan, Govindarajan, additional, Horsburgh, Charles, additional, Hochberg, Natasha, additional, Johnson, William Evan, additional, Knudsen, Selby, additional, Salgame, Padmini, additional, Ellner, Jerrold, additional, Prakash Babu, Senbagavalli, additional, and Sarkar, Sonali, additional

Published
2021
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50. ‘People listen more to what actors say’: A qualitative study of tuberculosis-related knowledge, behaviours, stigma, and potential interventions in Puducherry, India

Author

Sabin, Lora L, primary, Thulasingam, Mahalakshmy, additional, Carwile, Madeline, additional, Babu, Senbagavalli Prakash, additional, Knudsen, Selby, additional, Dong, Lijia, additional, Stephens, Jessie, additional, Fernandes, Priyanka, additional, Cintron, Chelsie, additional, Horsburgh, C Robert, additional, Salgame, Padmini, additional, Ellner, Jerrold J, additional, Sarkar, Sonali, additional, and Hochberg, Natasha S, additional

Published
2021
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