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9. Antibody escape and global spread of SARS-CoV-2 lineage A.27

Author

Kaleta, Tamara, Kern, Lisa, Hong, Samuel Leandro, Hölzer, Martin, Kochs, Georg, Beer, Julius, Schnepf, Daniel, Schwemmle, Martin, Bollen, Nena, Kolb, Philipp, Huber, Magdalena, Ulferts, Svenja, Weigang, Sebastian, Dudas, Gytis, Wittig, Alice, Jaki, Lena, Padane, Abdou, Lagare, Adamou, Salou, Mounerou, Ozer, Egon Anderson, Nnaemeka, Ndodo, Odoom, John Kofi, Rutayisire, Robert, Benkahla, Alia, Akoua-Koffi, Chantal, Ouedraogo, Abdoul-Salam, Simon-Lorière, Etienne, Enouf, Vincent, Kröger, Stefan, Calvignac-Spencer, Sébastien, Baele, Guy, Panning, Marcus, and Fuchs, Jonas

Published
2022
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12. Metabolomics and transcriptomics identify pathway differences between visceral and subcutaneous adipose tissue in colorectal cancer patients: the ColoCare study 1 , 2

Author

Liesenfeld, David B, Grapov, Dmitry, Fahrmann, Johannes F, Salou, Mariam, Scherer, Dominique, Toth, Reka, Habermann, Nina, Böhm, Jürgen, Schrotz-King, Petra, Gigic, Biljana, Schneider, Martin, Ulrich, Alexis, Herpel, Esther, Schirmacher, Peter, Fiehn, Oliver, Lampe, Johanna W, and Ulrich, Cornelia M

Subjects
Clinical Research, Cancer, Digestive Diseases, Obesity, Nutrition, Colo-Rectal Cancer, Aetiology, 2.1 Biological and endogenous factors, Metabolic and endocrine, Aged, Biomarkers, Carcinoma, Cohort Studies, Colorectal Neoplasms, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Intra-Abdominal Fat, Lipid Metabolism, Male, Metabolomics, Middle Aged, Neoplasm Staging, Oligonucleotide Array Sequence Analysis, Panniculitis, Paraneoplastic Syndromes, Prospective Studies, Subcutaneous Fat, Abdominal, colorectal cancer, obesity, adipose tissue, visceral adiposity, metabolomics, inflammation, Engineering, Medical and Health Sciences, Nutrition & Dietetics
Abstract

BackgroundMetabolic and transcriptomic differences between visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) compartments, particularly in the context of obesity, may play a role in colorectal carcinogenesis. We investigated the differential functions of their metabolic compositions.ObjectivesBiochemical differences between adipose tissues (VAT compared with SAT) in patients with colorectal carcinoma (CRC) were investigated by using mass spectrometry metabolomics and gene expression profiling. Metabolite compositions were compared between VAT, SAT, and serum metabolites. The relation between patients' tumor stage and metabolic profiles was assessed.DesignPresurgery blood and paired VAT and SAT samples during tumor surgery were obtained from 59 CRC patients (tumor stages I-IV) of the ColoCare cohort. Gas chromatography time-of-flight mass spectrometry and liquid chromatography quadrupole time-of-flight mass spectrometry were used to measure 1065 metabolites in adipose tissue (333 identified compounds) and 1810 metabolites in serum (467 identified compounds). Adipose tissue gene expression was measured by using Illumina's HumanHT-12 Expression BeadChips.ResultsCompared with SAT, VAT displayed elevated markers of inflammatory lipid metabolism, free arachidonic acid, phospholipases (PLA2G10), and prostaglandin synthesis-related enzymes (PTGD/PTGS2S). Plasmalogen concentrations were lower in VAT than in SAT, which was supported by lower gene expression of FAR1, the rate-limiting enzyme for ether-lipid synthesis in VAT. Serum sphingomyelin concentrations were inversely correlated (P = 0.0001) with SAT adipose triglycerides. Logistic regression identified lipids in patients' adipose tissues, which were associated with CRC tumor stage.ConclusionsAs one of the first studies, we comprehensively assessed differences in metabolic, lipidomic, and transcriptomic profiles between paired human VAT and SAT and their association with CRC tumor stage. We identified markers of inflammation in VAT, which supports prior evidence regarding the role of visceral adiposity and cancer.

Published
2015

13. Spectroscopic study of interfaces in Al/Ni periodic multilayers

Author

Guen, K. Le, Gamblin, G., Jonnard, Philippe, Salou, M., Youssef, J. Ben, Rioual, S., and Rouvellou, B.

Subjects
Condensed Matter - Materials Science
Abstract

Using electron-induced X-ray emission spectroscopy (XES), we have studied two Al/Ni periodic multilayers that differ only by their annealing temperature: as-deposited and annealed at 115C. Our aim is to show that XES can provide further details about the chemistry at the metal-metal interface, in addition to what is obtained by X-ray diffraction. The distribution of valence states exhibiting Al 3p and Ni 3d character is determined from the analysis of the Al Kbeta and Ni Lalpha emission bands respectively. The multilayer emission bands are compared to those of reference materials: pure Al and Ni metals as well as Al3Ni, Al3Ni2 and AlNi intermetallics. We provide evidence that, for temperatures up to 115C, Al3Ni is the major component of the multilayer., Comment: 5 pages. Can also be found at : http://www.epjap.org/action/displayAbstract?fromPage=online\&aid=8011580

Published
2013
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14. New experimental setup for in situ measurement of slow ion induced sputtering

Author

Salou, P., Lebius, H., Benyagoub, A., Langlinay, T., Lelièvre, D., and Ban-d'Etat, B.

Subjects
Physics - Instrumentation and Detectors
Abstract

A new experimental equipment allowing to study the sputtering induced by ion beam irradiation is presented. The sputtered particles are collected on a catcher which is analyzed in situ by Auger electron spectroscopy without breaking the ultra high vacuum (less than 10-9mbar), avoiding thus any problem linked to possible contamination. This method allows to measure the angular distribution of sputtering yield. Thanks to this new setup it is now possible to study the sputtering of many elements especially light elements such as carbon based materials. Preliminary results are presented in the case of highly oriented pyrolytic graphite and tungsten irradiated by an Ar+ beam at respectively 2.8 keV and 7 keV.

Published
2013

15. Prevalence of severe adverse events among health professionals after receiving the first dose of the ChAdOx1 nCoV-19 coronavirus vaccine (Covishield) in Togo, March 2021

Author

Konu, Yao Rodion, Gbeasor-Komlanvi, Fifonsi Adjidossi, Yerima, Mouhoudine, Sadio, Arnold Junior, Tchankoni, Martin Kouame, Zida-Compaore, Wendpouire Ida Carine, Nayo-Apetsianyi, Josée, Afanvi, Kossivi Agbélénko, Agoro, Sibabe, Salou, Mounerou, Landoh, Dadja Essoya, Nyansa, Atany B., Boko, Essohanam, Mijiyawa, Moustafa, and Ekouevi, Didier Koumavi

Published
2021
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24. Experimental evidence for spinodal decomposition in multifragmentation of heavy systems

Author

INDRA Collaboration, Tabacaru, G., Borderie, B., Rivet, M. F., Chomaz, P., Colonna, M., Frankland, J. D., Guarnera, A., Parlog, M., Bouriquet, B., Chbihi, A., Salou, S., and Wieleczko, J. P.

Subjects
Nuclear Experiment
Abstract

Multifragmentation of fused systems was observed for central collisions between 32 AMeV 129Xe and Sn, and 36 AMeV 155Gd and U. Previous extensive comparisons between the two systems led to the hypothesis of spinodal decomposition of finite systems as the origin of multifragmentation for incident energies around 30 AMeV. New results on velocity and charge correlations of fragments bring strong arguments in favor of this interpretation., Comment: 5 pages, 3 figures, Contribution to Bologna 2000, Structure of the Nucleus at the Dawn of the Century, Bologna, Italy, May 29 - June 3, 2000, to be published by World Scientific

Published
2001

25. Experimental and Theoretical Search for a Phase Transition in Nuclear Fragmentation

Author

Chbihi, A., Schapiro, O., Salou, S., and Gross, D. H. E.

Subjects
Nuclear Theory, Condensed Matter - Statistical Mechanics, Nuclear Experiment
Abstract

Phase transitions of small isolated systems are signaled by the shape of the caloric equation of state e^*(T), the relationship between the excitation energy per nucleon e^* and temperature. In this work we compare the experimentally deduced e^*(T) to the theoretical predictions. The experimentally accessible temperature was extracted from evaporation spectra from incomplete fusion reactions leading to residue nuclei. The experimental e^*(T) dependence exhibits the characteristic S-shape at e^* = 2-3 MeV/A. Such behavior is expected for a finite system at a phase transition. The observed dependence agrees with predictions of the MMMC-model, which simulates the total accessible phase-space of fragmentation.

Published
1999

28. Efficacy and safety of three antiretroviral therapy regimens for treatment-naive African adults living with HIV-2 (FIT-2): a pilot, phase 2, non-comparative, open-label, randomised controlled trial

Author

Eholie, Serge P, Ekouevi, Didier K, Chazallon, Corine, Charpentier, Charlotte, Messou, Eugène, Diallo, Zelica, Zoungrana, Jacques, Minga, Albert, Ngom Gueye, Ndeye Fatou, Hawerlander, Denise, Dembele, Fassery, Colin, Géraldine, Tchounga, Boris, Karcher, Sophie, Le Carrou, Jérome, Tchabert-Guié, Annick, Toni, Thomas-d'Aquin, Ouédraogo, Abdoul-Salam, Bado, Guillaume, Toure Kane, Coumba, Seydi, Moussa, Poda, Armel, Mensah, Ephrem, Diallo, Illah, Drabo, Youssouf Joseph, Anglaret, Xavier, Brun-Vezinet, Françoise, Anglaret, Xavier, Assoumou, Lambert, Bado, Guillaume, Bissagnene, Emmanuel, Bonnet, Fabrice, Britto, Carlos, Brun Vezinet, Françoise, Charpentier, Charlotte, Chazallon, Corine, Chenal, Henri, Chêne, Geneviève, Chenier, Remy, Clouet, Gwenaelle, Colin, Géraldine, Collin, Gilles, Conte, Valérie, Danel, Christine, De Monteynard, Laure-Amélie, Dembele, Fassery, Diallo, Zelica, Diallo, Illah, Dohoun, Lambert, Drabo, Youssouf Joseph, Eholié, Serge Paul, Ekouevi, Didier Koumavi, Fadiga, Fatoumata, Gabillard, Delphine, Girard, Pierre Marie, Gottlieb, Geoffrey S., Hawerlander, Denise, Karcher, Sophie, Kariyiare, Benjamin, Koita Fall, Mame Basty, Konan, Romuald, Kouame, Antoine, Kouley, Serge-Olivier, Laborde Bolen, Gabriele, Landman, Roland, Le Carrou, Jérome, Marcelain, Anne Geneviève, Matheron, Sophie, Mensah, Ephrem, Mercier, Noémie, Messou, Assoua, Messou, Eugène, Minga, Albert, N'dour, Cheick Tidiane, N'chot, Celestin, Ndiaye, Bara, Ngom Gueye, Ndeye Fatou, N'guessan-Koffi, Larissa, Ouattara, Eric, Ouédraogo, Abdoul-Salam, Palokinam Pitche, Vincent, Peytavin, Gilles, Plantier, Jean Christophe, Poda, Armel, Prince-David, Mireille, Raffali, Yasmine, Rekacewicz, Claire, Rouzioux, Christine, Salou, Mounerou, Sangare, Lassana, Sawadogo, Adrien Bruno, Seydi, Moussa, Somé, Désiré, Tamegnon, Séphora, Tchabert-Guié, Annick, Tchounga, Boris, Toni, Thomas d'Aquin, Toure Kane, Coumba, Touret, Pierre, Traoré, Jean-Richard, Vitoria de Avila, Marco Antonio, Yaméogo, Seydou, Yao Yapi, Cyrille, and Zoungrana, Jacques

Abstract

Due to the low number of individuals with HIV-2, no randomised trials of HIV-2 treatment have ever been done. We hypothesised that a non-comparative study describing the outcomes of several antiretroviral therapy (ART) regimens in parallel groups would improve understanding of how differences between HIV-1 and HIV-2 might lead to different therapeutic approaches.

Published
2024
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32. Concordance of CT imaging and surgical lesions in penetrating abdominal trauma.

Author

Perrin, Jean-Mathieu, Monchal, Tristan, Texier, Gaëtan, Salou-Regis, Laure, and Goudard, Yvain

Subjects
PENETRATING wounds, COMPUTED tomography, CRONBACH'S alpha, ABDOMINAL surgery, ELECTRONIC records
Abstract

The management of penetrating abdominal wounds has greatly benefited from the development of computed tomography (CT), particularly in stable patients. In this setting, the scanner is the reference examination. Our study aims to evaluate the performance of preoperative CT in the assessment of penetrating abdominal lesions. Between January 1, 2015 and January 1, 2022, 81 patients were hospitalized following penetrating abdominal trauma at the Army Training Hospitals of Sainte-Anne and Laveran. Fifty-one stable patients who had an abdominopelvic CT scan and thereafter underwent abdominal surgery (laparotomy or laparoscopy) were included. Radiological and surgical data were collected from the electronic record and compared by a descriptive analysis (calculation of the sensitivity, specificity, positive and negative predictive value of the CT for the detection of lesions of the various organs) and by a correlation of the CT findings with surgical findings using Kripendorff's alpha coefficient. The cohort was largely male (n = 45; 88%), with injuries by knife wound in 62.7% of cases (n = 32) and gunshot in 35.3% (n = 18) of cases. The median age was 36 years (25–47). The median index of severity score (ISS) was 17 (10–26). Excellent agreement between predicted and actual findings was obtained for solid organs (α = 0.801) with high sensitivity and specificity (81.8% and 96.6%, respectively). The largest discrepancies were observed for the hollow organs (α = 26.2%, sensitivity of 53.3% and specificity of 76.2%) and the diaphragm (α = 67.3%, sensitivity 75%, specificity 92.3%). Surgical exploration was non-therapeutic for five patients (9.8%). The failure rate for non-operative treatment was 10% (n = 1). CT detection of solid organ lesions in patients with penetrating abdominal wounds is excellent. However, the detection of hollow organ and diaphragmatic wounds remains a challenge with a risk of over- and underdiagnosis. Laparoscopic exploration should be able to fill in the gaps in the CT findings. [ABSTRACT FROM AUTHOR]

Published
2023
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33. Safety and efficacy of malaria vaccine candidate R21/Matrix-M in African children: a multicentre, double-blind, randomised, phase 3 trial

Author

Datoo, Mehreen S, Dicko, Alassane, Tinto, Halidou, Ouédraogo, Jean-Bosco, Hamaluba, Mainga, Olotu, Ally, Beaumont, Emma, Ramos Lopez, Fernando, Natama, Hamtandi Magloire, Weston, Sophie, Chemba, Mwajuma, Compaore, Yves Daniel, Issiaka, Djibrilla, Salou, Diallo, Some, Athanase M, Omenda, Sharon, Lawrie, Alison, Bejon, Philip, Rao, Harish, Chandramohan, Daniel, Roberts, Rachel, Bharati, Sandesh, Stockdale, Lisa, Gairola, Sunil, Greenwood, Brian M, Ewer, Katie J, Bradley, John, Kulkarni, Prasad S, Shaligram, Umesh, Hill, Adrian V S, Mahamar, Almahamoudou, Sanogo, Koualy, Sidibe, Youssoufa, Diarra, Kalifa, Samassekou, Mamoudou, Attaher, Oumar, Tapily, Amadou, Diallo, Makonon, Dicko, Oumar Mohamed, Kaya, Mahamadou, Maguiraga, Seydina Oumar, Sankare, Yaya, Yalcouye, Hama, Diarra, Soumaila, Niambele, Sidi Mohamed, Thera, Ismaila, Sagara, Issaka, Sylla, Mala, Dolo, Amagana, Misidai, Nsajigwa, Simando, Sylvester, Msami, Hania, Juma, Omary, Gutapaka, Nicolaus, Paul, Rose, Mswata, Sarah, Sasamalo, Ibrahim, Johaness, Kasmir, Sultan, Mwantumu, Alexander, Annastazia, Kimaro, Isaac, Lwanga, Kauye, Mtungwe, Mwajuma, Khamis, Kassim, Rugarabam, Lighton, Kalinga, Wilmina, Mohammed, Mohammed, Kamange, Janeth, Msangi, Jubilate, Mwaijande, Batuli, Mtaka, Ivanny, Mhapa, Matilda, Mlaganile, Tarsis, Mbaga, Thabit, Yerbanga, Rakiswende Serge, Samtouma, Wendkouni, Sienou, Abdoul Aziz, Kabre, Zachari, Ouedraogo, Wendinpui Jedida Muriel, Yarbanga, G Armel Bienvenu, Zongo, Issaka, Savadogo, Hamade, Sanon, Joseph, Compaore, Judicael, Kere, Idrissa, Yoni, Ferdinand Lionel, Sanre, Tewende Martine, Ouattara, Seydou Bienvenu, Provstgaard-Morys, Samuel, Woods, Danielle, Snow, Robert W., Amek, Nyaguara, Ngetsa, Caroline J., Ochola-Oyier, Lynette Isabella, Musyoki, Jennifer, Munene, Marianne, Mumba, Noni, Adetifa, Uche Jane, Muiruri, Charles Mwangi, Mwawaka, Jimmy Shangala, Mwaganyuma, Mwatasa Hussein, Ndichu, Martha Njeri, Weya, Joseph Ochieng, Njogu, Kelvin, Grant, Jane, Webster, Jayne, Lakhkar, Anand, Ido, N. Félix André, Traore, Ousmane, Tahita, Marc Christian, Bonko, Massa dit Achille, Rouamba, Toussaint, Ouedraogo, D. Florence, Soma, Rachidatou, Millogo, Aida, Ouedraogo, Edouard, Sorgho, Faizatou, Konate, Fabé, and Valea, Innocent

Abstract

Recently, we found that a new malaria vaccine, R21/Matrix-M, had over 75% efficacy against clinical malaria with seasonal administration in a phase 2b trial in Burkina Faso. Here, we report on safety and efficacy of the vaccine in a phase 3 trial enrolling over 4800 children across four countries followed for up to 18 months at seasonal sites and 12 months at standard sites.

Published
2024
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34. Diagnostic evaluation of paediatric autoimmune lymphoproliferative immunodeficiencies (ALPID): a prospective cohort study

Author

Hägele, Pauline, Staus, Paulina, Scheible, Raphael, Uhlmann, Annette, Heeg, Maximilian, Klemann, Christian, Maccari, Maria Elena, Ritterbusch, Henrike, Armstrong, Martin, Cutcutache, Ioana, Elliott, Katherine S, von Bernuth, Horst, Leahy, Timothy Ronan, Leyh, Jörg, Holzinger, Dirk, Lehmberg, Kai, Svec, Peter, Masjosthusmann, Katja, Hambleton, Sophie, Jakob, Marcus, Sparber-Sauer, Monika, Kager, Leo, Puzik, Alexander, Wolkewitz, Martin, Lorenz, Myriam Ricarda, Schwarz, Klaus, Speckmann, Carsten, Rensing-Ehl, Anne, Ehl, Stephan, Abinun, Mario, Abrahamsen, Tore, Albert, Michael, Almalky, Mohamed, Altaf, Sadaf, Babayeva, Royala, Bakhtiar, Shahrzad, Baris, Safa, Baumann, Ulrich, Becker, Martina, Berger, Thomas, Biebl, Ariane, Bielack, Stefan, Biskup, Saskia, Bismarck, Philipp, Bode, Sebastian, Borchers, Regine, Boztug, Carl Friedrich, Brockmann, Knut, Bruwier, Annelyse, Buchholz, Bernd, Cant, Andrew, Castro, Carla N, Classen, Carl, Claviez, Alexander, Crazzolara, Roman, Cuntz, Franziska, Dąbrowska-Leonik, Nel, Derichs, Ute, Dückers, Gregor, Eberl, Wolfgang, Ebetsberger-Dachs, Georg, Erlacher, Miriam, Fabre, Alexandre, Faletti, Laura, Farmand, Susan, Figueiredo, Antonio, Fischer, Marco, Flaadt, Tim, Full, Hermann, Gambineri, Eleonora, Girschick, Hermann, Goldacker, Sigune, Grimbacher, Bodo, Groß, Miriam, Gruhn, Andrew J, Gungoren, Ezgi, Haberfellner, Florian, Hague, Rosie, Hauch, Holger, Hauck, Fabian, Heine, Sabine, Holzinger, Dirk, Huisman, Elise, Jakovljevic, Gordana, James, Beki, Janda, Ales, Janda, Małgorzata, Jones, Neil, Kaiser-Labusch, Petra, Kentouche, Karim, Knight, Julian, Knirsch, Stephanie, Kontny, Udo, Körholz, Julia, Krenn, Ezgi Yalcin, Kuehnle, Ingrid, Kühne, Thomas, Lee-Dimroth, Jae-Yun, Lehmann, Hartwig, Leipold, Michael H., Meinhardt, Andrea, Mönkemöller, Kirsten, Morbach, Henner, Mücke, Urs, Nathrath, Michaela, Naumann-Bartsch, Nora, Neth, Olaf, Niemeyer, Charlotte, Olbrich, Peter, Ostró, Róbert, Owens, Stephen, Pac, Malgorzata, Pachlopnik Schmid, Rita, Page, Markus G., Pekrun, Arnulf, Prader, Seraina, Proietti, Michele, Puzik, Alexander, Rajacic, Nada, Rothoeft, Tobias, Ryan, Freimut H., Salou, Sarah, Salzer, Elisabeth, Savic, Sinisa, Schilling, Antonio E., Schmid, Jana, Schönberger, Stefan, Schuetz, Catharina, Schuez-Havupalo, Tore G., Schulte, Björn, Schulz, Ansgar, Schuster, Volker, Seidel, Markus, Siepermann, Kathrin, Smisek, Petr, Soomann, Maarja, Stiefel, Martina, Storck, Simone, Strahm, Brigitte, Streiter, Elise J, Teltschik, Charlotte M., Thalhammer, Julian, Tippelt, Stephan, Toskov, Vasil, Trück, Johannes, Vieth, Simon, Wegehaupt, Oliver, and Wiesel, Thomas

Abstract

Lymphoproliferation and autoimmune cytopenias characterise autoimmune lymphoproliferative syndrome. Other conditions sharing these manifestations have been termed autoimmune lymphoproliferative syndrome-like diseases, although they are frequently more severe. The aim of this study was to define the genetic, clinical, and immunological features of these disorders to improve their diagnostic classification.

Published
2024
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40. Gamma-radiation of Glossina palpalis gambiensis revisited: effect on fertility and mating competitiveness.

Author

Pagabeleguem, Soumaïla, Koughuindida, Oumar, Salou, Ernest Wendemanegde, Gimonneau, Geoffrey, Toé, Ange Irénée, Kaboré, Bénéwendé Aristide, Dera, Kiswend-sida Mikhailou, Maïga, Hamidou, Belem, Adrien Marie Gaston, Sanou/Ouédraogo, Gisèle Marie Sophie, Vreysen, Marc JB, and Bouyer, Jeremy

Abstract

Copyright of Parasite (1252607X) is the property of EDP Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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42. Evaluation of follow-up and long-term outcomes of gunshot and stab wounds in a French civilian population.

Author

Fournier, Julie, Salou-Regis, Laure, Pauleau, Ghislain, Goin, Géraldine, de La Villeon, Bruno, and Goudard, Yvain

Abstract

Purpose: The data concerning long-term follow-up and outcomes of penetrating trauma are poorly detailed in the literature. The main objective of our study was to analyze the hospital and extra-hospital follow-up of penetrating trauma victims and to evaluate the late complications and long-term consequences of these traumas.Methods: This work was a retrospective longitudinal monocentric observational study conducted at Laveran Military Hospital, from January 2007 to January 2017. All patients hospitalized for gunshot wound or stab wound management during this period were identified via a retrospective systematic query in the hospital information system using the ICD-10 codes. Epidemiological data, traumatism characteristics, hospital management, follow-up and traumatism consequences (i.e., persistent disability) were analyzed. To improve evaluation of traumatism long-term consequences, extra-hospital follow-up data from general physicians (GP) were collected by phone call. During this interview, 9 closed questions were asked to the GP. The survey evaluated: the date of the last consultation related to injury with the GP, the specific follow-up carried out by the GP, traumatism consequences, and recurrence of traumatism. Descriptive, univariate and multivariate with regression analysis were used for statistical analysis.Results: A total number of 165 patients were included. Median (Q1, Q3) of hospital follow-up was 28 (4, 66) days. One hundred one patients (61.2%) went to their one-month consultation at hospital. GP follow-up was achieved for 76 patients (55.2%). Median (Q1, Q3) of GP follow-up was 47 (21, 75) months. Twenty-four patients (14.5%) have been totally lost to follow up. The overall follow-up identified 54 patients (32.7%) with long-term consequences, 20 being psychiatric disorders and 30 organic injuries. Organic consequences were mainly peripheral nerve damages (n = 20; 12.1%). Most of the psychiatric consequences were diagnosed during GP follow-up (n = 14; 70%). Seventeen cases (10.3%) of recurrence were found and late mortality occurred in 4 patients (2.4%). High injury severity score, older age and gunshot wound were significantly linked to long-term consequences. Data collection and analysis were carried out in accordance with MR004 reference methodology.Conclusion: This study showed a high rate of long-term consequences among patients managed for penetrating injury. If all organic lesions are diagnosed during hospital follow-up and jointly managed by hospital and extra-hospital physicians, most socio-psychiatric consequences were detected and followed by extra-hospital workers. However, for half of the patients, the extra-hospital follow-up could not be assessed. Thus, these consequences are very probably underestimated. It appears imperative to strengthen the compliance and adherence of these patients to the care network. Awareness and involvement of medical, paramedical teams and GP role seems essential to screen and manage these consequences. [ABSTRACT FROM AUTHOR]

Published
2022
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43. Prompt light particle emission in the 36Ar + 58Ni reaction at 95 MeV/nucleon

Author

Pawłowski, P., Borderie, B., Auger, G., Bacri, Ch.O., Bellaize, N., Bocage, F., Bougault, R., Brou, R., Buchet, P., Charvet, J.L., Chbihi, A., Colin, J., Cussol, D., Dayras, R., Demeyer, A., Doré, D., Durand, D., Frankland, J.D., Galichet, E., Genouin-Duhamel, E., Gerlic, E., Guinet, D., Lautesse, P., Laville, J.L., Lecolley, J.F., Legrain, R., Le Neindre, N., Lopez, O., Louvel, M., Maskay, A.M., Nalpas, L., Nguyen, A.D., Pârlog, M., Péter, J., Plagnol, E., Rivet, M.F., Rosato, E., Saint-Laurent, F., Salou, S., Steckmeyer, J.C., Stern, M., Tăbăcaru, G., Tamain, B., Tassan-Got, L., Tirel, O., Vient, E., Volant, C., Wieleczko, J.P., and (INDRA Collaboration)

Published
2000
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44. Emission time scale of light particles in the system Xe+Sn at 50 AMeV. A probe for dynamical emission?

Author

Gourio, D., Ardouin, D., Assenard, M., Auger, G., Bacri, Ch.O., Bellaize, N., Benkirane, A., Benlliure, J., Berthier, B., Bisquer, E., Borderie, B., Bougault, R., Box, P., Brou, R., Charvet, J.L., Chbihi, A., Colin, J., Cussol, D., Dayras, R., De Filippo, E., Demeyer, A., Donnet, C., Durand, D., Ecomard, P., Eudes, P., Germain, M., Guinet, D., Lakehal-Ayat, L., Lautesse, P., Laville, J.L., Lebreton, L., Le Brun, C., Lecolley, J.F., Lefort, T., Lefèvre, A., Legrain, R., Le Neindre, N., Lopez, O., Louvel, M., Marie, N., Métivier, V., Nalpas, L., Ouatizerga, A., Parlog, M., Péter, J., Plagnol, E., Pollaco, E., Rahmani, A., Régimbart, R., Reposeur, T., Rivet, M.F., Rosato, E., Saint-Laurent, F., Salou, S., Squalli, M., Steckmeyer, J.C., Tabacaru, G., Tamain, B., Tassan-Got, L., Vient, E., Volant, C., Wieleczko, J.P., Wieloch, A., and Yuasa-Nakagawa, K.

Published
2000
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45. Thermal and chemical equilibrium for vaporizing sources

Author

Borderie, B., Gulminelli, F., Rivet, M.F., Tassan-Got, L., Assenard, M., Auger, G., Bocage, F., Bougault, R., Brou, R., Buchet, Ph., Colin, J., Dayras, R., Demeyer, A., Frankland, J.D., Galichet, E., Genouin-Duhamel, E., Gerlic, E., Germain, M., Guinet, D., Lautesse, P., Laville, J.L., Lecolley, J.F., Lefort, T., Legrain, R., Le Neindre, N., Louvel, M., Maskay, A.M., Nalpas, L., Nguyen, A.D., Parlog, M., Plagnol, E., Rahmani, A., Reposeur, T., Rosato, E., Saint-Laurent, F., Salou, S., Steckmeyer, J.C., Stern, M., Tabacaru, G., Tamain, B., Tirel, O., Vintache, D., Volant, C., and The INDRA Collaboration

Published
1999
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46. Experimental evidence that immune trypanolysis using the LiTat 1.3 and LiTat 1.5 variant antigen types is not specific to Trypanosoma brucei gambiense in pigs.

Author

Ilboudo, Kadidiata, Hounyeme, Robert Eustache, Kabore, Jacques, Boulangé, Alain, Gimonneau, Geoffrey, Salou, Ernest, Belem, Adrien Gaston Marie, Lejon, Veerle, Compaoré, Charlie Franck Alfred, Bucheton, Bruno, Koffi, Mathurin, Solano, Philippe, Berthier, David, Thevenon, Sophie, and Jamonneau, Vincent

Abstract

Copyright of Parasite (1252607X) is the property of EDP Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022
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48. Growth and energetics of Leuconostoc oenos during cometabolism of glucose with citrate or fructose

Author

Loubiere, P., Salou, P., and Pareilleux, A.

Subjects
Bacteria -- Growth, Glucose metabolism -- Analysis, Biological sciences
Abstract

Analysis of growth of mixed-substrate clusters of Leuconostoc oenos, with citrate or fructose as a glucose cosubstrate, shows that growth stimulation results from the cometabolism of the substrates. The growth of L. oenos is energy limited with respect to the biomass produced and rates of these anabolic reactions. Cosubstrates affect fermentation by changing the number and/or the importance of the reduced end products.

Published
1994

49. Assessment of α-Cypermethrin Pour-On Application and Diminazene Aceturate for Treating Trypanosome-Related Diseases Caused by Tsetse Flies on Cattle in Mô, Togo

Author

Soudah, Boma, Essodina, Talaki, Toï, N’feide, Balabadi, Dao, Yao, Lombo, Martin Bienvenu, Somda, and Wendemanegde Ernest, Salou

Abstract

The effects of tsetse-transmitted trypanosomosis control in high tsetse flies (Glossina spp.) challenge and trypanocidal drug resistance settings remain poorly understood in Togo owing to poor data coverage on the current disease impact. From March 2014 to November 2017, a database of zoo-sanitary surveys integrating the evolution of disease incidence and intervention coverage made it possible to quantify the apparent effects attributable to the control effort, focused on all sedentary cattle breeds in the 1,000 km² area of Mô in Togo. The strategy involved an initial phase with cross-sectional entomological and parasitological. Then, three times a year, 20% of the bovine animals of the study area received α-cypermethrin pour-on, and infected cattle with poor health (798 cattle in 2014 and 358 in 2017) were individually given diminazene aceturate at 7 mg/kg of body weight. The tsetse density in the area decreased significantly, from 1.78 ± 0.37 in March 2014 before the α-cypermethrin application to 0.48 ± 0.07 in February 2017. The α-cypermethrin pour-on application and diminazene aceturate treatment of cattle led to the largest reduction in disease incidence, from 28.1% in 2014 to 7.8% in 2017, an improvement in hematocrit from 24.27 ± 4.9% to 27.5 ± 4.6%, and a reduction in calf mortality from 15.9 ± 11% to 5.9%. Improved access to these interventions for different types of livestock and maintaining their effectiveness, despite high tsetse (Diptera: Glossinidae) challenges, should be the primary focus of control strategies in many areas of Togo.

Published
2022
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50. PKGANESA: an ECRIS for Testing the Axisymmetric Magnetic Structure for the Production of Multicharged Ion Beams

Author

Salou, P., Maunoury, L., Gaubert, G., Michel, M., Lecesne, N., Leroy, R., Besnier, D., Pantechnik, Grand Accélérateur National d'Ions Lourds (GANIL), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Lion, Michel, and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS.PHYS.PHYS-ACC-PH]Physics [physics]/Physics [physics]/Accelerator Physics [physics.acc-ph], [PHYS.PHYS.PHYS-ACC-PH] Physics [physics]/Physics [physics]/Accelerator Physics [physics.acc-ph]
Abstract

International audience; After the development in the 90’s of the mono-charged ion source [1] based on a axisymmetricmagnetic structure, the next step towards multicharged ion source has been undertaken withthe Multigan ion source [2]. The preliminary results did not fully demonstrate the abilityof this source to produce high charge states. Therefore, GANIL and Pantechnik got bothinvolved in a collaboration to develop an ECRIS prototype using an optimized axisymmetricmagnetic structure devoted to the production of high charge state ions at 10 GHz of RFfrequency.Magnetic structure has been designed, mechanic parts have been machined and assembledbefore setting this ion source called PKGANESA on a dedicated test bench at the Pantechnikcompany.This contribution shall present the PKGANESA characteristics: magnetic structure, mechanicaldesign, RF design as well as measurements done at Pantechnik on the charge statesdistributions obtained with Ar and the evolutions of CSD regarding RF power, bias electrodesand buffer gases.

Published
2017

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