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Objective. To identify the population of human immunodeficiency virus–infected pediatric long- term survivors (LTS) followed in major medical institutions in California, Florida and New Jersey. Methods. A cross-sectional survey was performed with data collection forms sent to all investigators. Demographic, clinical, and laboratory data were obtained on all living patients ≥8 years infected in the perinatal period with human immunodeficiency virus. Results. A total of 143 perinatally infected and 54 children infected by neonatal transfusion were identified. Fifty-four children (27%) had absolute CD4 counts ≥500 cells/mm3(group 1: mean age 9.8 years), 54 children (27%) had CD4 counts between 200 and 500 cells/mm3 (group 2: mean age 10.1 years), and 89 children (45%) had CD4 counts Conclusions. Pediatric LTS were in variable stages of disease progression. The proportion of children within each CD4 strata did not differ by mode of acquisition of infection. Increased CD4 counts were inversely proportional to age. Only 20% of pediatric LTS had minimal to no disease progression. HIV, pediatric long-term survivors, slow disease progression.

INCREASING INCIDENCE OF HETEROSEXUAL TRANSMISSION OF THE HUMAN IMMUNODEFICIENCY VIRUS (HIV) IN MOTHERS OF INFANTS WITH AIDS OR ARC