1. Molecular epidemiology of multidrug-resistant Acinetobacter baumannii isolates from hospitals in Myanmar
- Author
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Tatsuya Tada, Hiroki Uchida, Tomomi Hishinuma, Shin Watanabe, Mari Tohya, Kyoko Kuwahara-Arai, San Mya, Khin Nyein Zan, Teruo Kirikae, and Htay Htay Tin
- Subjects
Multidrug-resistant Acinetobacter baumannii ,16S rRNA methylase ,molecular epidemiology ,Microbiology ,QR1-502 - Abstract
Objective: The aim of this study was to clarify the genetic and epidemiological properties of multidrug-resistant Acinetobacter baumannii in medical settings in Myanmar. Methods: A total of 45 A. baumannii clinical isolates were obtained in medical settings in Myanmar. The whole genomes were sequenced by a next generation sequencer, and the phylogenetic tree was constructed from single nucleotide polymorphism concatemers. Multilocus sequence types were deduced and drug resistance genes were identified. Results: Thirty-eight MDR Acinetobacter baumannii isolates were obtained from seven hospitals in Myanmar. The majority of MDR A. baumannii isolates belonged to ST2. Of the 38 isolates, 5 harbored blaNDM-1, and 28 did armA or armA2 Conclusions: A. baumannii ST2 producing 16S rRNA methylase ArmA has been spreading in medical settings in Myanmar.
- Published
- 2020
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