6 results on '"Sanabria, Rafael Mauricio"'
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2. “Can I go to Glasgow?” Learnings from patient involvement at the 17th Congress of the International Society for Peritoneal Dialysis (ISPD)
- Author
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Gutman, Talia, primary, Manera, Karine E, additional, Baumgart, Amanda, additional, Johnson, David W, additional, Wilkie, Martin, additional, Boudville, Neil, additional, Craig, Jonathan C, additional, Dong, Jie, additional, Jesudason, Shilpa, additional, Mehrotra, Rajnish, additional, Neu, Alicia, additional, Shen, Jenny I, additional, Van Biesen, Wim, additional, Blake, Peter G, additional, Brunier, Gillian, additional, Cho, Yeoungjee, additional, Jefferson, Nichole, additional, Lenga, Ilan, additional, Mann, Neelem, additional, Mendelson, Asher A, additional, Perl, Jeffrey, additional, Sanabria, Rafael Mauricio, additional, Scholes-Roberston, Nicole, additional, Schwartz, Daniel, additional, Teitelbaum, Isaac, additional, and Tong, Allison, additional
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- 2020
- Full Text
- View/download PDF
3. Impact of Medium Cut-Off Dialyzers on Patient-Reported Outcomes: COREXH Registry.
- Author
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Alarcon, Juan Carlos, Bunch, Alfonso, Ardila, Freddy, Zuñiga, Eduardo, Vesga, Jasmin I., Rivera, Angela, Sánchez, Ricardo, and Sanabria, Rafael Mauricio
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RESTLESS legs syndrome ,QUALITY of life ,SYMPTOMS ,KIDNEY diseases - Abstract
Introduction: A new generation of hemodialysis (HD) membranes called medium cut-off (MCO) membranes possesses enhanced capacities for middle molecule clearance, which have been associated with adverse outcomes in this population. These improvements could potentially positively impact patient-reported outcomes (PROs). Objective: The objective of this study was to evaluate the impact of MCO membranes on PROs in a cohort of HD patients in Colombia. Methods: This was a prospective, multicenter, observational cohort study of 992 patients from 12 renal clinics in Colombia who were switched from high-flux HD to MCO therapy and observed for 12 months. Changes in Kidney Disease Quality of Life 36-Item Short Form Survey (KDQoL-SF36) domains, Dialysis Symptom Index (DSI), and restless legs syndrome (RLS) 12 months after switching to MCO membranes were compared with time on high-flux membranes. Repeated measures of ANOVA were used to evaluate changes in KDQoL-SF36 scores; severity scoring was used to assess DSI changes over time; Cochran's Q test was used to evaluate changes in frequency of diagnostic criteria of RLS. Results: During 12 months of follow-up, 3 of 5 KDQoL-SF36 domains improved compared with baseline: symptoms (p < 0.0001), effects of kidney disease (p < 0.0001), and burden of kidney disease (p < 0.001). The proportion of patients diagnosed with RLS significantly decreased from 22.1% at baseline to 10% at 12 months (p < 0.0001). No significant differences in the number of symptoms (DSI, p = 0.1) were observed, although their severity decreased (p = 0.009). Conclusions: In conventional HD patients, the expanded clearance of large middle molecules with MCO-HD membranes was associated with higher health-related quality of life scores and a decrease in the prevalence of RLS. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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4. Factores asociados con la falla del acceso vascular de hemodiálisis en pacientes con enfermedad renal crónica
- Author
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García López, Andrea Elena, Sanabria, Rafael Mauricio (Thesis advisor), and Sánchez Pedraza, Ricardo
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Fístula arteriovenosa ,Hemodiálisis ,Hemodialysis ,Acceso vascular ,Failure ,Vascular access ,Central venous catheter ,Arteriovenous fistula - Abstract
Introducción: Un acceso vascular funcional es esencial para el bienestar de los pacientes en hemodiálisis (HD) ya que su disfunción es una de las mayores causas de morbilidad. Conocer los factores asociados a su falla se considera una prioridad. Objetivo: Estimar los factores asociados a la falla del acceso vascular de hemodiálisis en pacientes con enfermedad renal crónica (ERC). Metodología: Estudio observacional analítico de cohorte histórica, conformada por adultos con ERC en HD tratados en las clínicas de Renal Therapy Services (RTS) en Colombia entre el 1 de enero y 31 de diciembre de 2016. Se evaluó asociación entre un grupo de variables independientes y el tiempo a la falla del acceso vascular mediante un análisis de supervivencia, y se ajustó por variables basales usando un modelo de regresión de Cox. Resultados: En la cohorte de 985 pacientes que iniciaron HD, el 51.27% (n=505) experimentó un cambio de acceso durante el seguimiento para un total de 1774 accesos evaluados. De estos, 1152 (64.9%) correspondieron a un acceso temporal (AVT) y 622 (35%) a un acceso permanente (AVP). La incidencia de falla en toda la cohorte fue 66.3 x 100 personas-año y los factores asociados fueron la edad (HR 2.8; p=0.008), procedencia rural (HR 17.8; p=0.00), hemoglobina (HR 0.70; p=0.021) y diabetes (HR 3.39; p=0.019) en los AVP y albumina (HR 1.2; p=0.035), hipertensión (HR 1.4; p=0.02) y hemoglobina (HR 0.9; p= 0.034) para los AVT. Conclusión: Los factores relacionados con la falla del AVP fueron edad avanzada, procedencia rural, diabetes y niveles bajos de hemoglobina y los relacionados con la falla del AVT fueron niveles bajos de hemoglobina, la hipertensión y niveles altos de albumina. Abstract: Introduction: A functional vascular access is essential for the well-being of patients in hemodialysis (HD) since their dysfunction is a major cause of morbidity. The factors associated with failure of the vascular access is considered a priority. Objective: To estimate factors associated with vascular access failure in Chronic Kidney Disease (CKD) patients with hemodialysis. Methods: We conducted a retrospective cohort study, conformed by adults with CKD in HD treated in clinics of Renal Therapy Services (RTS) in Colombia between January 1th and December 31th, 2016. Association among a group of independent variables and time to failure of the vascular access through a survival analysis was evaluated and adjusted by baseline variables using a Cox regression model. Results: A cohort of 985 patients in HD was evaluated, among 51.27% (n = 505) experienced a vascular access conversion during follow-up for a total of 1774 observations. Of these, 1152 (64.9%) corresponded to a temporary vascular access (TVA) and 622 (35%) to a permanent vascular access (PVA). The incidence of failure in the entire cohort was 66.3 x 100 person-years and the associated factors were age (HR 2.08; p = 0.008), rural origin (HR 17.8 ; p = 0.00) and hemoglobin (HR 0.70; p = 0.021) and diabetes (HR 3.39; p = 0.019) in PVA and albumin (HR 1.2; p = 0.035) , hypertension (HR 1.4; p = 0.02) and hemoglobin (0.9 HR; p = 0.034) for TVA. Conclusion: Factors related to the failure of the PVA were elderly, rural origin, diabetes and low levels of hemoglobin and the failure of TVA was related to low levels of hemoglobin, high blood pressure and high levels of albumin. Maestría
- Published
- 2019
5. Estudio de los perfiles de progresión de la enfermedad renal crónica en una población intervenida con un programa de prevención secundaria
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Ramos Montaña, Jesús David, Pardo Turriago, Campo Elías, and Sanabria, Rafael Mauricio
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progression trajectory of chronic kidney disease ,análisis armónico cualitativo ,harmonic qualitative analysis ,61 Ciencias médicas ,Medicina / Medicine and health ,enfermedad renal Crónica ,análisis multivariado de datos ,6 Tecnología (ciencias aplicadas) / Technology ,31 Colecciones de estadística general / Statistics ,5 Ciencias naturales y matemáticas / Science ,clasificación de datos cualitativos longitudinales ,análisis factorial múltiple ,chronic kidney disease - Abstract
Se combina el análisis armónico cualitativo (AAC) con el análisis factorial múltiple (AFM) para determinar distintas clases de trayectorias de pacientes con enfermedad renal crónica (ERC) e identificar variables clínicas y sociodemográficas asociadas a la evolución temporal de la enfermedad. Abstract: qualitative harmonic analysis (QHA) and multiple factor analysis (MFA) are combined to determine different types of trajectories of patients with chronic kidney disease (CKD) and to identify clinical and sociodemographic variables associated with the temporal evolution of the disease. Maestría
- Published
- 2016
6. "Can I go to Glasgow?" Learnings from patient involvement at the 17th Congress of the International Society for Peritoneal Dialysis (ISPD).
- Author
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Gutman T, Manera KE, Baumgart A, Johnson DW, Wilkie M, Boudville N, Craig JC, Dong J, Jesudason S, Mehrotra R, Neu A, Shen JI, Van Biesen W, Blake PG, Brunier G, Cho Y, Jefferson N, Lenga I, Mann N, Mendelson AA, Perl J, Sanabria RM, Scholes-Roberston N, Schwartz D, Teitelbaum I, and Tong A
- Subjects
- Adult, Aged, Female, Humans, Internationality, Kidney Diseases psychology, Kidney Diseases therapy, Male, Middle Aged, Nephrology, Attitude of Health Personnel, Biomedical Research, Congresses as Topic, Patient Participation, Peritoneal Dialysis, Societies, Medical
- Abstract
Background: Recognition of the discrepancy between the research priorities of patients and health professionals has prompted efforts to involve patients as active contributors in research activities, including scientific conferences. However, there is limited evidence about the experience, challenges, and impacts of patient involvement to inform best practice. This study aims to describe patient and health professional perspectives on patient involvement at the Congress of the International Society for Peritoneal Dialysis (ISPD)., Methods: Semi-structured interviews were conducted with 14 patients/caregivers and 15 health professionals from six countries who attended ISPD. Interviews were recorded and transcribed verbatim, and transcripts were analyzed thematically., Results: We identified four themes: protecting and enhancing scientific learning (grounding science in stories, sharing and inspiring new perspectives, distilling the key messages of research presentations, striking a balance between accommodating patients and presenting the science); democratizing access to research (redistributing power, challenging the traditional ownership of knowledge, cultivating self-management through demystifying research); inadequate support for patient/caregiver delegates (lacking purposeful inclusion, challenges in interpreting research findings, soliciting medical advice, difficulty negotiating venue and program, limited financial assistance in attending); and amplifying impact beyond the room (sparking innovation in practice, giving patients and families hope for the future)., Conclusions: Patient involvement at the ISPD Congress clarified the applicability of research to patient care and self-management, democratized science, and strengthened the potential impact of research. More structured support for patients to help them purposefully articulate their experience in relation to session objectives may enhance their contribution and their own learning experience.
- Published
- 2020
- Full Text
- View/download PDF
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