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11 results on '"Sanchez-Munoz-Torrero, Juan F."'

1. Improved lipid-lowering treatment and reduction in cardiovascular disease burden in homozygous familial hypercholesterolemia: The SAFEHEART follow-up study

Author

Alonso, Rodrigo, Arroyo-Olivares, Raquel, Díaz-Díaz, Jose Luis, Fuentes-Jiménez, Francisco, Arrieta, Francisco, de Andrés, Raimundo, Gonzalez-Bustos, Pablo, Argueso, Rosa, Martin-Ordiales, Mercedes, Martinez-Faedo, Ceferino, Illán, Fátima, Saenz, Pedro, Donate, José María, Sanchez Muñoz-Torrero, Juan F., Martinez-Hervas, Sergio, and Mata, Pedro

Published
2024
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2. The Added Value of Coronary Calcium Score in Predicting Cardiovascular Events in Familial Hypercholesterolemia

Author

Angoulvant, Denis, Beliard, Sophie, Boccara, Franck, Bruckert, Eric, Cariou, Bertrand, Carreau, Valérie, Carrie, Alain, Charrieres, Sybil, Cottin, Yves, Di Filippo, Mathilde, Ducluzeau, Pierre Henri, Dulong, Sonia, Durlach, Vincent, Farnier, Michel, Ferrari, Emile, Ferrieres, Dorota, Ferrieres, Jean, Gallo, Antonio, Giral, Philippe, Gonbert, Sophie, Hankard, Regis, Inamo, Jocelyn, Kalmykova, Olga, Krempf, Michel, Lemale, Julie, Moulin, Philippe, Paillard, François, Peretti, Noel, Perrin, Agnes, Pradignac, Alain, Rabes, Jean Pierre, Rigalleau, Vincent, Schiele, François, Sultan, Ariane, Tounian, Patrick, Valero, René, Verges, Bruno, Yelnik, Cecile, Ziegler, Olivier, Aguado, Rocío, Alonso, Rodrigo, Álvarez-Baños, M<ce:sup loc='post">a</ce:sup> Pilar, Argüeso, Rosa, Arrieta, Francisco, Barba, Miguel Ángel, Casañas, Marta, Cepeda, José María, De Andrés, Raimundo, Díaz-Soto, Gonzalo, Díaz-Diaz, Jose Luis, Dieguez, Marta, Faedo, Ceferino, Fuentes, Francisco, Garrido, Juan A., González, Aurora, González-Bustos, Pablo, Mañas, M<ce:sup loc='post">a</ce:sup> Dolores, Mata, Pedro, Mauri, Marta, Mediavilla, Juan Diego, Michán, Alfredo, Miramontes, Pablo, Muñiz, Ovidio, Pérez, Leire, De Isla, Leopoldo Perez, Pintó, Xavier, Romero, Manuel J., Rubio, Patricia, Sánchez Muñoz-Torrero, Juan F., Vidal-Pardo, Jose I., Zambón, Daniel, Pérez de Isla, Leopoldo, Charrière, Sybil, Vimont, Alexandre, Muñiz-Grijalvo, Ovidio, Díaz-Díaz, José L., and Béliard, Sophie

Published
2021
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3. Incidencia de eventos cardiovasculares y cambios en el riesgo estimado y en el tratamiento de la hipercolesterolemia familiar: registro SAFEHEART

Author

Aguado, Rocío, Perez-Corral, Begoña, Almagro, Fátima, Alonso, Rodrigo, Arroyo, Raquel, Mata, Nelva, Mata, Pedro, Isla, Leopoldo Pérez de, Saltijeral, Adriana, Arrieta, Francisco, Badimón, Lina, Padró, Teresa, Barba, Miguel Ángel, Brea, Ángel, Mosquera, Daniel, Casañas, Marta, Carbayo, Julio, Cepeda, Jose María, De Andrés, Raimundo, Díaz, José L., Díaz-Soto, Gonzalo, Diéguez, Marta, Riestra, María, Fuentes, Francisco, López-Miranda, José, Galiana, Jesús, Mañas, M. Dolores, García-Cruces, Jesús, Garrido, Juan Antonio, Irigoyen, Luis, Martínez, Pedro L., Martínez-Faedo, Ceferino, Suárez, Lorena, Mauri, Marta, Borrallo, Rosa M., Mediavilla, Juan Diego, Jaén, Fernando, González, Pablo, Michán, Alfredo, Rubio, Patricia, Miramontes, Pablo, Morera, Juan L., Muñiz, Ovidio, González, Aurora, Pereyra, Francisca, Pérez, Leire, Piedecausa, Mar, Pastor, José, Pinilla, José Miguel, Pintó, Xavier, Romero, Manuel J., Ruiz, Enrique, Álvarez, M. Pilar, Sáenz, Pedro, Sánchez, Juan F., Sanz, Consuelo, Vidal, Jose I., Argüeso, Rosa, Zambón, Daniel, Pérez de Isla, Leopoldo, Arroyo-Olivares, Raquel, Muñiz-Grijalvo, Ovidio, Díaz-Díaz, José Luis, Sánchez Muñoz-Torrero, Juan F., Miramontes-González, José Pablo, de Andrés, Raimundo, Cepeda, José M., Vidal-Pardo, José I., Ruiz-Pérez, Enrique, Riestra Fernández, María, and Pinilla, José M.

Published
2020
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4. Long-term effect of 2 intensive statin regimens on treatment and incidence of cardiovascular events in familial hypercholesterolemia: The SAFEHEART study

Author

Pérez de Isla, Leopoldo, Arroyo-Olivares, Raquel, Muñiz-Grijalvo, Ovidio, Diaz-Díaz, José Luis, Zambón, Daniel, Fuentes, Francisco, Sánchez Muñoz-Torrero, Juan F., Mediavilla, Juan Diego, González-Estrada, Aurora, Miramontes-González, Jose Pablo, de Andrés, Raimundo, Mauri, Marta, Mosquera, Daniel, Cepeda, José M., Suárez, Lorena, Barba-Romero, Miguel Ángel, Argüeso, Rosa, Álvarez-Baños, Pilar, Michán, Alfredo, Romero-Jiménez, Manuel J., García-Cruces, Jesús, Padró, Teresa, Alonso, Rodrigo, and Mata, Pedro

Published
2019
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6. Statins do not increase the risk of developing type 2 diabetes in familial hypercholesterolemia: The SAFEHEART study

Author

Fuentes, Francisco, Alcala-Diaz, Juan F., Watts, Gerald F., Alonso, Rodrigo, Muñiz, Ovidio, Díaz-Díaz, José L., Mata, Nelva, Sanchez Muñoz-Torrero, Juan F., Brea, Ángel, Galiana, Jesús, Figueras, Rosaura, Aguado, Rocio, Piedecausa, Mar, Cepeda, Jose M., Vidal, Juan I., Rodríguez-Cantalejo, Fernando, López-Miranda, Jose, and Mata, Pedro

Published
2015
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9. Prediction of early mortality in patients with cancer-associated thrombosis in the rIete Database

Author

Fuentes, Harry E., Tafur, Alfonso J., Caprini, Joseph A., Alatri, Adriano, Trujillo-santos, Javier, Farge-bancel, Dominique, Rosa, Vladimir, Font, Llorenc, Vilaseca, Alicia, Monreal, Manuel, Adarraga, Maria D., Aibar, Miguel A., Aibar, Jesus, Amado, Cristina, Aranda, Carlos, Arcelus Juan, I, Ballaz, Aitor, Barba, Raquel, Barillari, Giovanni, Barron, Manuel, Barron-Andres, Belen, Bascunana, Jose, Benzidia, Ilham, Bertoletti, Laurent, Blanco-Molina, Angeles, Bilora, Franca, Bortoluzzi, Cristiano, Bosevski, Marijan, Bounameaux, Henri, Braester, Andrei, Brandolin, Barbara, Brenner, Benjamin, Bucherini, Eugenio, Hanh My Bui, Bura-Riviere, Alessandra, Camon, Ana M., Carrasco, Cristina, Castro, Joaquin, Cesta, Alisia, Ciammaichella, Maurizio, Cruz, Javier A., de Ancos, Cristina, del Toro, Jorge, Demelo, Pablo, Dentali, Francesco, del Carmen Diaz-pedroche, Maria, Diaz-Peromingo, Jose A., Di Micco, Pierpaolo, Di Pangrazio, Marco, Ellis, Martin, Encabo, Marta, Falga, Conxita, Falvo, Nicolas, Farfan Ana, Fernandez-Capitan, Carmen, Angeles Fidalgo, Maria, Font, Carme, Fresa, Marco, Furest, Ildefonso, Garcia, Maria A., Garcia-Braoado, Ferran, Garcia-Morillo, Marcia, Garcia-Raso, Aranzazu, Gavin, Olga, Gil-Diaz, Aida, Gomez, Vicente, Gomez-Cuervo, Covadonga, Gonzalez-Martinez, Jose, Grandone, Elvira, Grau, Enric, Guijarro, Ricardo, Gutierrez, Javier, Gutierrez, Paula, Hernandez-Blasco, Luis, Hu, Adrian, Hirmerova, Jana, Imbalzano, Egidio, Jara-Palomares, Luis, Jaras, Maria J., Jimenez, David, Jou, Ines, Joya, Maria D., Krstevski, Gorjan, Lessiani, Gianfranco, Lima, Jorge, Llamas, Pilar, Lobo, Jose L., Lopez-Jimenez, Luciano, Lopez-Miguel, Patricia, Lopez-Nunez, Juan J., Lopez-Reyes, Raquel, Lopez-Saez, Juan B., Lorente, Manuel A., Lorenzo, Alicia, Loring, Monica, Lumbierres, Marina, Mahe, Isabelle, Maida, Rosa, Maly, Radovan, Manrique-Abos, Isabel, Marchena, Pablo J., Martin-Fernandez, Miguel, Martin-Guerra, Javier M., Martin-Romero, Miguel, Mastroiacovo, Danicla, Mazzolai, Lucia, Mellado, Meritxell, Merah, Adel, del Valle Morales, Maria, Moustafa, Fares, Ney, Barbara, Nieto, Jose A., Nunez, Manuel J., del Carmen Olivares, Maria, Otalora, Sonia, Otero, Remedios, Pace, Federica, Parisi, Roberto, Pedrajas, Jose Maria, Pellejero, Galadriel, Perez-Ductor, Cristina, Perez-Jacoiste, Asuncion, Perez-Rus, Gloria, Peris, Maria L., Pesavento, Raffaele, Pesce, Maria L., Porras, Jose A., Prandoni, Paolo, Quinta-Valla, Roberto, Riesco, David, Rivas, Agustina, Rocci, Anna, Rodriguez-Davila, Maria A., Rodriguez-Hernandez, Adela, Rubio, Carmen M., Ruiz-Alcaraz, Sandra, Ruiz-Artacho, Pedro, Ruiz-Ruiz, Justo, Ruiz-Sada, Pablo, Ruiz-Torregrosa, Paloma, Sahuquillo, Joan C., Sala-Sainz, Carmen, Salgado, Estuardo, Samperiz, Angel, Sanchez-Munoz-Torrero, Juan F., Sancho, Teresa, Sanoja, Indra D., Siniscalchi, Carmine, Skride, Andris, Soler, Silvia, Sotgiu, Pietro, Soto, Maria J., Surinach, Jose M., Tiraferri, Eros, Tonello, Diego, Torres Maria, Tufano, Antonella, Tzoran, Inns, Uresandi, Fernando, Usandizaga, Esther, Valle, Reins, Vanassche, Thomas, Vandenbriele, Christophe, Vazquez, Fernando J., Verhamme, Peter, Villalobos, Aurora, Visona, Adriana, Ngoc Vo Hong, Yoo, Hugo H., Zdraveska, Marija, Fuentes, Harry E., Tafur, Alfonso J., Caprini, Joseph A., Alatri, Adriano, Trujillo-santos, Javier, Farge-bancel, Dominique, Rosa, Vladimir, Font, Llorenc, Vilaseca, Alicia, Monreal, Manuel, Adarraga, Maria D., Aibar, Miguel A., Aibar, Jesu, Amado, Cristina, Aranda, Carlo, Arcelus, Juan, I, Ballaz, Aitor, Barba, Raquel, Barillari, Giovanni, Barron, Manuel, Barron-Andres, Belen, Bascunana, Jose, Benzidia, Ilham, Bertoletti, Laurent, Blanco-Molina, Angele, Bilora, Franca, Bortoluzzi, Cristiano, Bosevski, Marijan, Bounameaux, Henri, Braester, Andrei, Brandolin, Barbara, Brenner, Benjamin, Bucherini, Eugenio, Hanh My, Bui, Bura-Riviere, Alessandra, Camon, Ana M., Carrasco, Cristina, Castro, Joaquin, Cesta, Alisia, Ciammaichella, Maurizio, Cruz, Javier A., de Ancos, Cristina, del Toro, Jorge, Demelo, Pablo, Dentali, Francesco, del Carmen Diaz-pedroche, Maria, Diaz-Peromingo, Jose A., Di Micco, Pierpaolo, Di Pangrazio, Marco, Ellis, Martin, Encabo, Marta, Falga, Conxita, Falvo, Nicola, Farfan, Ana, Fernandez-Capitan, Carmen, Angeles Fidalgo, Maria, Font, Carme, Fresa, Marco, Furest, Ildefonso, Garcia, Maria A., Garcia-Braoado, Ferran, Garcia-Morillo, Marcia, Garcia-Raso, Aranzazu, Gavin, Olga, Gil-Diaz, Aida, Gomez, Vicente, Gomez-Cuervo, Covadonga, Gonzalez-Martinez, Jose, Grandone, Elvira, Grau, Enric, Guijarro, Ricardo, Gutierrez, Javier, Gutierrez, Paula, Hernandez-Blasco, Lui, Hu, Adrian, Hirmerova, Jana, Imbalzano, Egidio, Jara-Palomares, Lui, Jaras, Maria J., Jimenez, David, Jou, Ine, Joya, Maria D., Krstevski, Gorjan, Lessiani, Gianfranco, Lima, Jorge, Llamas, Pilar, Lobo, Jose L., Lopez-Jimenez, Luciano, Lopez-Miguel, Patricia, Lopez-Nunez, Juan J., Lopez-Reyes, Raquel, Lopez-Saez, Juan B., Lorente, Manuel A., Lorenzo, Alicia, Loring, Monica, Lumbierres, Marina, Mahe, Isabelle, Maida, Rosa, Maly, Radovan, Manrique-Abos, Isabel, Marchena, Pablo J., Martin-Fernandez, Miguel, Martin-Guerra, Javier M., Martin-Romero, Miguel, Mastroiacovo, Danicla, Mazzolai, Lucia, Mellado, Meritxell, Merah, Adel, del Valle Morales, Maria, Moustafa, Fare, Ney, Barbara, Nieto, Jose A., Nunez, Manuel J., del Carmen Olivares, Maria, Otalora, Sonia, Otero, Remedio, Pace, Federica, Parisi, Roberto, Pedrajas, Jose Maria, Pellejero, Galadriel, Perez-Ductor, Cristina, Perez-Jacoiste, Asuncion, Perez-Rus, Gloria, Peris, Maria L., Pesavento, Raffaele, Pesce, Maria L., Porras, Jose A., Prandoni, Paolo, Quinta-Valla, Roberto, Riesco, David, Rivas, Agustina, Rocci, Anna, Rodriguez-Davila, Maria A., Rodriguez-Hernandez, Adela, Rubio, Carmen M., Ruiz-Alcaraz, Sandra, Ruiz-Artacho, Pedro, Ruiz-Ruiz, Justo, Ruiz-Sada, Pablo, Ruiz-Torregrosa, Paloma, Sahuquillo, Joan C., Sala-Sainz, Carmen, Salgado, Estuardo, Samperiz, Angel, Sanchez-Munoz-Torrero, Juan F., Sancho, Teresa, Sanoja, Indra D., Siniscalchi, Carmine, Skride, Andri, Soler, Silvia, Sotgiu, Pietro, Soto, Maria J., Surinach, Jose M., Tiraferri, Ero, Tonello, Diego, Torres, Maria, Tufano, Antonella, Tzoran, Inn, Uresandi, Fernando, Usandizaga, Esther, Valle, Rein, Vanassche, Thoma, Vandenbriele, Christophe, Vazquez, Fernando J., Verhamme, Peter, Villalobos, Aurora, Visona, Adriana, Ngoc Vo, Hong, Yoo, Hugo H., and Zdraveska, Marija

Subjects
Adult, Male, Internationality, Adolescent, Population, 030204 cardiovascular system & hematology, 030230 surgery, computer.software_genre, Logistic regression, Risk Assessment, Cohort Studies, Young Adult, 03 medical and health sciences, Mortality, Neoplasms, Premature, Thrombosis, 0302 clinical medicine, Predictive Value of Tests, Risk Factors, Humans, Medicine, Registries, Child, education, Aged, education.field_of_study, Framingham Risk Score, Database, business.industry, Infant, Newborn, Infant, Venous Thromboembolism, Odds ratio, Middle Aged, medicine.disease, Pulmonary embolism, Logistic Models, Child, Preschool, Predictive value of tests, Multivariate Analysis, Female, Cardiology and Cardiovascular Medicine, Risk assessment, business, computer, Cohort study
Abstract

BACKGROUND: Proper risk stratification of patients for early mortality after cancer-associated thrombosis may lead to personalized anticoagulation protocols. Therefore, we aimed to derive and validate a scoring system to predict early mortality in this population. To this end, we selected patients with active cancer and thrombosis from the Computerized Registry of Patients with Venous Thromboembolism database. METHODS: The main outcome was all cause mortality within the month following a thrombotic event. We used a simple random selection to split are data in a derivation and a validation cohort. In the derivation cohort, we used recursive partitioning and binary logistic regression to identify groups at risk and to determine the likelihood of the primary outcome. The risk score was developed based on odds ratios from the final multivariate model, and then tested in the validation cohort. RESULTS: In 10,025 eligible patients, we identified 6 predictors of 30-day mortality: leukocytosis =11.5x109/L; platelet count =160x109/L, metastasis, recent immobility, initial presentation as pulmonary embolism and Body Mass Index

Published
2019

11. Attainment of LDL-Cholesterol Treatment Goals in Patients With Familial Hypercholesterolemia 5-Year SAFEHEART Registry Follow-Up

Author

Perez de Isla, Leopoldo, Alonso, Rodrigo, Watts, Gerald F, Mata, Nelva, Saltijeral Cerezo, Adriana, Muñiz, Ovidio, Fuentes, Francisco, Diaz-Diaz, José Luís, de Andrés, Raimundo, Zambón, Daniel, Rubio-Marin, Patricia, Barba-Romero, Miguel A, Saenz, Pedro, Sanchez Muñoz-Torrero, Juan F, Martinez-Faedo, Ceferino, Miramontes-Gonzalez, José P, Badimón, Lina, Mata, Pedro, SAFEHEART Investigators, [Perez de Isla, Leopoldo] Hosp Clin San Carlos, IDISSC, Dept Cardiol, Madrid, Spain, [Perez de Isla, Leopoldo] Fdn Hipercolesterolemia Familiar, C Gen Alvarez Castro 14, Madrid 28010, Spain, [Alonso, Rodrigo] Fdn Hipercolesterolemia Familiar, C Gen Alvarez Castro 14, Madrid 28010, Spain, [Mata, Nelva] Fdn Hipercolesterolemia Familiar, C Gen Alvarez Castro 14, Madrid 28010, Spain, [Saltijeral Cerezo, Adriana] Fdn Hipercolesterolemia Familiar, C Gen Alvarez Castro 14, Madrid 28010, Spain, [Mata, Pedro] Fdn Hipercolesterolemia Familiar, C Gen Alvarez Castro 14, Madrid 28010, Spain, [Alonso, Rodrigo] Clin Las Condes, Santiago, Chile, [Watts, Gerald F.] Royal Perth Hosp, Ctr Cardiovasc Med, Lipid Disorders Clin, Perth, WA 6001, Australia, [Watts, Gerald F.] Univ Western Australia, Sch Med & Pharmacol, Perth, WA 6009, Australia, [Mata, Nelva] Madrid Hlth Author, Dept Epidemiol, Madrid, Spain, [Saltijeral Cerezo, Adriana] Hosp Tajo, Dept Cardiol, Madrid, Spain, [Muniz, Ovidio] Hosp Virgen Rocio, Dept Internal Med, Seville, Spain, [Fuentes, Francisco] Univ Hosp, Dept Internal Med, Cordoba, Spain, [Luis Diaz-Diaz, Jose] Hosp Abente & Lago, Dept Internal Med, La Coruna, Spain, [de Andres, Raimundo] Fdn Jimenez Diaz, Dept Internal Med, E-28040 Madrid, Spain, [Zambon, Daniel] Hosp Clin Barcelona, Dept Endocrinol, Barcelona, Spain, [Rubio-Marin, Patricia] Hosp SAS Jerez Frontera, Dept Internal Med, Cadiz, Spain, [Barba-Romero, Miguel A.] Complejo Hosp Univ, Dept Internal Med, Albacete, Spain, [Saenz, Pedro] Hosp Merida, Dept Internal Med, Extremadura, Spain, [Sanchez Munoz-Torrero, Juan F.] Hosp San Pedro Alcantara, Dept Internal Med, Caceres, Spain, [Martinez-Faedo, Ceferino] Cent Hosp, Dept Endocrinol, Asturias, Spain, [Miramontes-Gonzalez, Jose P.] Univ Hosp, Dept Internal Med, Salamanca, Spain, [Badimon, Lina] IIB St Pau, Inst Catalan Ciencias Cardiovasc, Barcelona, Spain, Fundacion Hipercolesterolemia Familiar, Instituto de Salud Carlos III (ISCIII), Centro Nacional de Investigacion Cardiovascular (CNIC), Merck Sharp Dohme, AstraZeneca, AMGEN, AEGERION, ISIS, and Sanofi

Subjects
Adult, Male, Risk, Time Factors, Adolescent, Efficacy, Care, Hyperlipoproteinemia Type II, Young Adult, cardiovascular disease, Atorvastatin, Humans, Disease, Prospective Studies, Registries, Rosuvastatin Calcium, Mortality, low-density lipoprotein cholesterol, Dose-Response Relationship, Drug, LDL-receptor mutations, lipid-lowering therapy, Anticholesteremic Agents, Cohort, Cholesterol, LDL, Middle Aged, Ezetimibe, Management, Treatment Outcome, Spain, Guidance, Drug Therapy, Combination, Female, Therapy, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Biomarkers, Follow-Up Studies
Abstract

Familial hypercholesterolemia (FH) is the most common genetic disorder associated with premature atherosclerotic cardiovascular disease (ASCVD). There are sparse data on attainment of treatment targets; large registries that reflect real-life clinical practice can uniquely provide this information. We sought to evaluate the achievement of low-density lipoprotein cholesterol (LDL-C) treatment goals in FH patients enrolled in a large national registry. The SAFEHEART study (Spanish Familial Hypercholesterolemia Cohort Study) is a large, ongoing registry of molecularly defined patients with heterozygous FH treated in Spain. The attainment of guideline-recommended plasma LDL-C goals at entry and follow-up was investigated in relation to use of lipid-lowering therapy (LLT). The study recruited 4,132 individuals (3,745 of whom were ≥18 years of age); 2,752 of those enrolled were molecularly diagnosed FH cases. Mean follow-up was 5.1 ± 3.1 years; 71.8% of FH cases were on maximal LLT, and an LDL-C treatment target Despite the use of intensified LLT, many FH patients continue to experience high plasma LDL-C levels and, consequently, do not achieve recommended treatment targets. Type of LDL-receptor mutation, use of ezetimibe, coexistent diabetes, and ASCVD status can bear significantly on the likelihood of attaining LDL-C treatment goals.

Published
2016

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