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2. Supplementary Figure S3. The figure shows CNA profile of three IPMN samples. from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., primary, Bowitz Lothe, Inger Marie, primary, Labori, Knut Jørgen, primary, Dentro, Stefan C., primary, Buanes, Trond, primary, Skrede, Martina L., primary, Dalsgaard, Astrid M., primary, Munthe, Else, primary, Myklebost, Ola, primary, Lingjærde, Ole Christian, primary, Børresen-Dale, Anne-Lise, primary, Ikdahl, Tone, primary, Van Loo, Peter, primary, Nord, Silje, primary, and Kure, Elin H., primary

Published
2023
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3. Supplementary Figure S5. Frequency plot of the CNAs of periampullary adenocarcinomas based on site of origin. from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., primary, Bowitz Lothe, Inger Marie, primary, Labori, Knut Jørgen, primary, Dentro, Stefan C., primary, Buanes, Trond, primary, Skrede, Martina L., primary, Dalsgaard, Astrid M., primary, Munthe, Else, primary, Myklebost, Ola, primary, Lingjærde, Ole Christian, primary, Børresen-Dale, Anne-Lise, primary, Ikdahl, Tone, primary, Van Loo, Peter, primary, Nord, Silje, primary, and Kure, Elin H., primary

Published
2023
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4. Supplementary Table S1: Frequencies of gains and losses for selected genes in both OUH and TCGA cohorts. from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., primary, Bowitz Lothe, Inger Marie, primary, Labori, Knut Jørgen, primary, Dentro, Stefan C., primary, Buanes, Trond, primary, Skrede, Martina L., primary, Dalsgaard, Astrid M., primary, Munthe, Else, primary, Myklebost, Ola, primary, Lingjærde, Ole Christian, primary, Børresen-Dale, Anne-Lise, primary, Ikdahl, Tone, primary, Van Loo, Peter, primary, Nord, Silje, primary, and Kure, Elin H., primary

Published
2023
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5. Supplementary Figure S1. Heatmap shows the cytobands amplified and deleted in OUH and TCGA cohort. from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., primary, Bowitz Lothe, Inger Marie, primary, Labori, Knut Jørgen, primary, Dentro, Stefan C., primary, Buanes, Trond, primary, Skrede, Martina L., primary, Dalsgaard, Astrid M., primary, Munthe, Else, primary, Myklebost, Ola, primary, Lingjærde, Ole Christian, primary, Børresen-Dale, Anne-Lise, primary, Ikdahl, Tone, primary, Van Loo, Peter, primary, Nord, Silje, primary, and Kure, Elin H., primary

Published
2023
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6. Supplementary Figure S2. CNA profile of the two xenografts cell lines and their original tumors. from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., primary, Bowitz Lothe, Inger Marie, primary, Labori, Knut Jørgen, primary, Dentro, Stefan C., primary, Buanes, Trond, primary, Skrede, Martina L., primary, Dalsgaard, Astrid M., primary, Munthe, Else, primary, Myklebost, Ola, primary, Lingjærde, Ole Christian, primary, Børresen-Dale, Anne-Lise, primary, Ikdahl, Tone, primary, Van Loo, Peter, primary, Nord, Silje, primary, and Kure, Elin H., primary

Published
2023
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7. Data from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., primary, Bowitz Lothe, Inger Marie, primary, Labori, Knut Jørgen, primary, Dentro, Stefan C., primary, Buanes, Trond, primary, Skrede, Martina L., primary, Dalsgaard, Astrid M., primary, Munthe, Else, primary, Myklebost, Ola, primary, Lingjærde, Ole Christian, primary, Børresen-Dale, Anne-Lise, primary, Ikdahl, Tone, primary, Van Loo, Peter, primary, Nord, Silje, primary, and Kure, Elin H., primary

Published
2023
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8. Supplementary Table S3: Table shows the pathway deregulated in OUH and TCGA cohort. from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., primary, Bowitz Lothe, Inger Marie, primary, Labori, Knut Jørgen, primary, Dentro, Stefan C., primary, Buanes, Trond, primary, Skrede, Martina L., primary, Dalsgaard, Astrid M., primary, Munthe, Else, primary, Myklebost, Ola, primary, Lingjærde, Ole Christian, primary, Børresen-Dale, Anne-Lise, primary, Ikdahl, Tone, primary, Van Loo, Peter, primary, Nord, Silje, primary, and Kure, Elin H., primary

Published
2023
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9. Supplementary Figure S4. Correlation between genome instability index (GII) and ploidy. from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., primary, Bowitz Lothe, Inger Marie, primary, Labori, Knut Jørgen, primary, Dentro, Stefan C., primary, Buanes, Trond, primary, Skrede, Martina L., primary, Dalsgaard, Astrid M., primary, Munthe, Else, primary, Myklebost, Ola, primary, Lingjærde, Ole Christian, primary, Børresen-Dale, Anne-Lise, primary, Ikdahl, Tone, primary, Van Loo, Peter, primary, Nord, Silje, primary, and Kure, Elin H., primary

Published
2023
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10. Supplementary file: Legends of supplementary material from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., primary, Bowitz Lothe, Inger Marie, primary, Labori, Knut Jørgen, primary, Dentro, Stefan C., primary, Buanes, Trond, primary, Skrede, Martina L., primary, Dalsgaard, Astrid M., primary, Munthe, Else, primary, Myklebost, Ola, primary, Lingjærde, Ole Christian, primary, Børresen-Dale, Anne-Lise, primary, Ikdahl, Tone, primary, Van Loo, Peter, primary, Nord, Silje, primary, and Kure, Elin H., primary

Published
2023
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11. Supplementary Table S2: Table shows the correlation score (r) between allele frequency and gene expression from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., primary, Bowitz Lothe, Inger Marie, primary, Labori, Knut Jørgen, primary, Dentro, Stefan C., primary, Buanes, Trond, primary, Skrede, Martina L., primary, Dalsgaard, Astrid M., primary, Munthe, Else, primary, Myklebost, Ola, primary, Lingjærde, Ole Christian, primary, Børresen-Dale, Anne-Lise, primary, Ikdahl, Tone, primary, Van Loo, Peter, primary, Nord, Silje, primary, and Kure, Elin H., primary

Published
2023
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13. Author Correction: Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

Author

Chan-Seng-Yue, Michelle, Kim, Jaeseung C., Wilson, Gavin W., Ng, Karen, Figueroa, Eugenia Flores, O’Kane, Grainne M., Connor, Ashton A., Denroche, Robert E., Grant, Robert C., McLeod, Jessica, Wilson, Julie M., Jang, Gun Ho, Zhang, Amy, Liang, Sheng-Ben, Borgida, Ayelet, Chadwick, Dianne, Kalimuthu, Sangeetha, Lungu, Ilinca, Bartlett, John M. S., Krzyzanowski, Paul M., Sandhu, Vandana, Tiriac, Hervé, Froeling, Fieke E. M., Karasinska, Joanna M., Topham, James T., Renouf, Daniel J., Schaeffer, David F., Jones, Steven J. M., Marra, Marco A., Laskin, Janessa, Chetty, Runjan, Stein, Lincoln D., Zogopoulos, George, Haibe-Kains, Benjamin, Campbell, Peter J., Tuveson, David A., Knox, Jennifer J., Fischer, Sandra E., Gallinger, Steven, and Notta, Faiyaz

Published
2020
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15. 85: The Role of Cytokine Signaling in the Reversal of Chronic Lymphedema

Author

Kwan, Jennifer Yin Yee, primary, Xu, Wenxi, additional, Sandhu, Vandana, additional, Demidov, Valentin, additional, Shi, Willa, additional, Vitkin, Alex, additional, Jones, Jennifer, additional, Williams, Justin, additional, Haykal, Siba, additional, Haibe-Kains, Benjamin, additional, Brooks, David G., additional, Yip, Kenneth W., additional, and Liu, Fei-Fei, additional

Published
2020
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17. Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

Author

Chan-Seng-Yue, Michelle, primary, Kim, Jaeseung C., additional, Wilson, Gavin W., additional, Ng, Karen, additional, Figueroa, Eugenia Flores, additional, O’Kane, Grainne M., additional, Connor, Ashton A., additional, Denroche, Robert E., additional, Grant, Robert C., additional, McLeod, Jessica, additional, Wilson, Julie M., additional, Jang, Gun Ho, additional, Zhang, Amy, additional, Dodd, Anna, additional, Liang, Sheng-Ben, additional, Borgida, Ayelet, additional, Chadwick, Dianne, additional, Kalimuthu, Sangeetha, additional, Lungu, Ilinca, additional, Bartlett, John M. S., additional, Krzyzanowski, Paul M., additional, Sandhu, Vandana, additional, Tiriac, Hervé, additional, Froeling, Fieke E. M., additional, Karasinska, Joanna M., additional, Topham, James T., additional, Renouf, Daniel J., additional, Schaeffer, David F., additional, Jones, Steven J. M., additional, Marra, Marco A., additional, Laskin, Janessa, additional, Chetty, Runjan, additional, Stein, Lincoln D., additional, Zogopoulos, George, additional, Haibe-Kains, Benjamin, additional, Campbell, Peter J., additional, Tuveson, David A., additional, Knox, Jennifer J., additional, Fischer, Sandra E., additional, Gallinger, Steven, additional, and Notta, Faiyaz, additional

Published
2020
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18. Meta-Analysis of 1,200 Transcriptomic Profiles Identifies a Prognostic Model for Pancreatic Ductal Adenocarcinoma

Author

Sandhu, Vandana, primary, Labori, Knut Jorgen, additional, Borgida, Ayelet, additional, Lungu, Ilinca, additional, Bartlett, John, additional, Hafezi-Bakhtiari, Sara, additional, Denroche, Robert E., additional, Jang, Gun Ho, additional, Pasternack, Danielle, additional, Mbaabali, Faridah, additional, Watson, Matthew, additional, Wilson, Julie, additional, Kure, Elin H., additional, Gallinger, Steven, additional, and Haibe-Kains, Benjamin, additional

Published
2019
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19. Abstract 4623: Meta-analysis of transcriptomic profiles identifies prognostic model for pancreatic ductal adenocarcinoma patients

Author

Sandhu, Vandana, primary, Labori, Knut Jorgen, additional, Borgida, Ayelet, additional, Lungu, Ilinca, additional, Bartlett, John, additional, Hafezi-Bakhtiari, Sara, additional, Denroche, Rob, additional, Jang, Gun Ho, additional, Pasternack, Danielle, additional, Mbaabali, Faridah, additional, Watson, Matthew, additional, Wilson, Julie, additional, Kure, Elin H., additional, Gallinger, Steven, additional, and Haibe-Kains, Benjamin, additional

Published
2018
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20. Meta-analysis of 1,200 transcriptomic profiles identifies a prognostic model for pancreatic ductal adenocarcinoma

Author

Sandhu, Vandana, primary, Labori, Knut Jorgen, additional, Borgida, Ayelet, additional, Lungu, Ilinca, additional, Bartlett, John, additional, Hafezi-Bakhtiari, Sara, additional, Denroche, Rob, additional, Jang, Gun Ho, additional, Pasternack, Danielle, additional, Mbaabali, Faridah, additional, Watson, Matthew, additional, Wilson, Julie, additional, Kure, Elin H., additional, Gallinger, Steven, additional, and Haibe-Kains, Benjamin, additional

Published
2018
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22. Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy

Author

Eide, Hanne A., primary, Knudtsen, Ingerid Skjei, additional, Sandhu, Vandana, additional, Løndalen, Ayca M., additional, Halvorsen, Ann Rita, additional, Abravan, Azadeh, additional, Kure, Elin H., additional, Bogsrud, Trond V., additional, Brustugun, Odd Terje, additional, Kyte, Jon Amund, additional, Malinen, Eirik, additional, and Helland, Åslaug, additional

Published
2018
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23. A systems biology approach to integrated molecular analysis in pancreatic and periampullary adenocarcinoma

Author

Sandhu, Vandana

Subjects
periampullary adenocarcinoma, Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762 [VDP], pancreatic cancer, pancreatic adenocarcinoma
Abstract

Pancreatic and periampullary adenocarcinoma (PA) is a highly lethal disease, for which the mortality rate closely parallels the incidence rate. Most of the PA patients remain asymptomatic until the disease reaches an advanced stage with an overall survival of

Published
2016

24. Profiling of microRNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer

Author

Halvorsen, Ann Rita, primary, Helland, Åslaug, additional, Gromov, Pavel, additional, Wielenga, Vera Timmermans, additional, Talman, Maj-Lis Møller, additional, Brunner, Nils, additional, Sandhu, Vandana, additional, Børresen-Dale, Anne-Lise, additional, Gromova, Irina, additional, and Haakensen, Vilde D., additional

Published
2016
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25. Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease

Author

Eide, Hanne Astrid, primary, Halvorsen, Ann Rita, additional, Sandhu, Vandana, additional, Fåne, Anne, additional, Berg, Janna, additional, Haakensen, Vilde Drageset, additional, Kure, Elin H, additional, Brustugun, Odd Terje, additional, Kiserud, Cecilie Essholt, additional, Kyte, Jon Amund, additional, and Helland, Åslaug, additional

Published
2016
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26. The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma

Author

Sandhu, Vandana, primary, Wedge, David C., additional, Bowitz Lothe, Inger Marie, additional, Labori, Knut Jørgen, additional, Dentro, Stefan C., additional, Buanes, Trond, additional, Skrede, Martina L., additional, Dalsgaard, Astrid M., additional, Munthe, Else, additional, Myklebost, Ola, additional, Lingjærde, Ole Christian, additional, Børresen-Dale, Anne-Lise, additional, Ikdahl, Tone, additional, Van Loo, Peter, additional, Nord, Silje, additional, and Kure, Elin H., additional

Published
2016
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29. Molecular signatures of mRNAs and miRNAs as prognostic biomarkers in pancreatobiliary and intestinal types of periampullary adenocarcinomas

Author

Sandhu, Vandana, primary, Bowitz Lothe, Inger Marie, additional, Labori, Knut Jørgen, additional, Lingjærde, Ole Christian, additional, Buanes, Trond, additional, Dalsgaard, Astrid M., additional, Skrede, Martina, additional, Hamfjord, Julian, additional, Haaland, Terese, additional, Eide, Tor J., additional, Børresen-Dale, Anne-Lise, additional, Ikdahl, Tone, additional, and Kure, Elin H., additional

Published
2015
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30. Profiling of micro RNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer.

Author

Halvorsen, Ann Rita, Helland, Åslaug, Gromov, Pavel, Wielenga, Vera Timmermans, Talman, Maj‐Lis Møller, Brunner, Nils, Sandhu, Vandana, Børresen‐Dale, Anne‐Lise, Gromova, Irina, and Haakensen, Vilde D.

Abstract

It has been hypothesized based on accumulated data that a class of small noncoding RNAs, termed micro RNAs, are key factors in intercellular communication. Here, micro RNAs present in interstitial breast tumor fluids have been analyzed to identify relevant markers for a diagnosis of breast cancer and to elucidate the cross-talk that exists among cells in a tumor microenvironment. Matched tumor interstitial fluid samples ( TIF, n = 60), normal interstitial fluid samples ( NIF, n = 51), corresponding tumor tissue specimens ( n = 54), and serum samples ( n = 27) were collected from patients with breast cancer, and detectable micro RNAs were analyzed and compared. In addition, serum data from 32 patients with breast cancer and 22 healthy controls were obtained for a validation study. To identify potential serum biomarkers of breast cancer, first the micro RNA profiles of TIF and NIF samples were compared. A total of 266 micro RNAs were present at higher level in the TIF samples as compared to normal counterparts. Sixty-one of these micro RNAs were present in > 75% of the serum samples and were subsequently tested in a validation set. Seven of the 61 micro RNAs were associated with poor survival, while 23 were associated with the presence of immune cells and adipocytes. To our knowledge, these data demonstrate for the first time that profiling of micro RNAs in TIF can identify novel biomarkers for the prognostic classification and detection of breast cancer. In addition, the present findings demonstrate that micro RNAs may represent the cross-talk that occurs between tumor cells and their surrounding stroma. [ABSTRACT FROM AUTHOR]

Published
2017
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