Search

Your search keyword '"Sandri, G. B. L."' showing total 8 results
Start Over Author "Sandri, G. B. L."
8 results on '"Sandri, G. B. L."'

1. Current status of liver surgery for non-colorectal non-neuroendocrine liver metastases: the NON.LI.MET. Italian Society for Endoscopic Surgery and New Technologies (SICE) and Association of Italian Surgeons in Europe (ACIE) collaborative international survey

Author

Libia, A, Podda, M, Di Martino, M, Pata, F, Pellino, G, Di Saverio, S, Anselmo, A, Muttillo, E, De Pastena, M, Campanile, F, Ielpo, B, Spampinato, M, Guerrieri, M, Agresta, F, Cuccurullo, D, Sartori, A, D'Ambrosio, G, Anania, G, Agrusa, A, Allaix, M, Balla, A, Botteri, E, Bracale, U, Ceccarelli, G, Milone, M, Moretto, G, Muttillo, I, Perrotta, N, Pirozzi, F, Ortenzi, M, Ioannidis, A, Stavrou, G, Gica, N, Benzoni, E, Rosa, F, Visag-Castillo, V, Award, S, Machairas, N, Manrique, M, Marino, M, De Nobili, G, Sira-gusa, L, Iossa, A, de Santibanes, M, Lisi, G, De Luca, A, Giuliani, A, Perra, T, Porcu, A, Cillara, N, Giordano, A, Laureiro, Z, Papa, M, Clementi, M, Tamini, N, Soreide, K, Mazzarella, G, Pio, L, Dopazo, C, Argenio, G, An-nechiarico, M, Andreuccetti, J, Calvo, M, Cinardi, N, Angelico, R, Nari, G, Saldino, E, Gazia, C, Anis, B, Machian, G, Romic, I, Bellido-luque, J, Pandanapoyana, S, Roscio, F, Pattaccini, G, Frazzetta, G, Lim, R, Delvecchio, A, Primavesi, F, Rodrigeuz-Lopez, M, Formisano, G, Delogu, D, Umar, M, Elisa, S, Del Basso, C, D'Alessandro, A, Sandri, G, Menna, M, De Simone, B, al-Najami, I, Curro, G, Hila, J, Quaresima, S, Cervellera, M, Sanberg, J, Cestaro, G, Capuano, M, Ammendola, M, Pinotti, E, Palomba, G, Tonini, V, Baiocchi, G, Saraceno, F, Calini, G, Reccia, I, Dasari, B, Poillucci, G, Frontali, A, Marconi, M, Bertilone, E, Basile, E, Toneto, M, Coletta, D, Cacciaguerra, A, Umar Younis, M, Merlini, D, Julianov, A, Harish, N, Morelli, L, Marone, M, Lo Conte, D, D'Ugo, S, D'Acapito, F, Saroglu, A, Santambrogio, R, Giuffrida, M, Furbetta, N, Lopez-Lopez, V, Panyko, A, Romano, F, Murillo, G, Spartalis, M, Spartalis, E, Castaldi, A, Koh, P, Koong, J, Santiago, M, Grazi, G, Martinez-Mier, G, Beatriz, D, Gkekas, I, Ioannidis, O, Lujan, S, Carneros, V, Madrid, F, Baroffio, P, Rashid, A, Irkorucu, O, Ros, E, Perez-Bertolez, S, Schizas, D, Machain, G, Altinel, Y, Veroux, M, Corallino, D, Lorenzin, D, Negoi, I, Barabi-no, M, Piccino, M, Grossi, U, Fernandez, A, Saeidi, S, Maritato, S, Picco-lo, G, Serradilla-Martin, M, Esposito, G, Albanesi, F, Lammel-Lindemann, J, Libia A., Podda M., Di Martino M., Pata F., Pellino G., Di Saverio S., Anselmo A., Muttillo E. M., De Pastena M., Campanile F. C., Ielpo B., Spampinato M. G., Guerrieri M., Agresta F., Cuccurullo D., Sartori A., D'Ambrosio G., Anania G., Agrusa A., Allaix M. E., Balla A., Botteri E., Bracale U., Ceccarelli G., Milone M., Moretto G., Muttillo I., Perrotta N., Pirozzi F., Ortenzi M., Ioannidis A., Stavrou G., Gica N., Benzoni E., Rosa F., Visag-Castillo V., Award S. S., Machairas N., Manrique M. M., Marino M., De Nobili G., Sira-gusa L., Iossa A., de Santibanes M., Lisi G., De Luca A., Giuliani A., Perra T., Porcu A., Cillara N., Giordano A., Laureiro Z. L., Papa M. V., Clementi M., Tamini N., Soreide K., Mazzarella G., Pio L., Dopazo C., Argenio G., An-nechiarico M., Andreuccetti J., Calvo M. P., Cinardi N., Angelico R., Nari G. A., Saldino E., Gazia C., Anis B., Machian G. M., Romic I., Bellido-luque J., Pandanapoyana S., Roscio F., Pattaccini G. C., Frazzetta G., Lim R., Delvecchio A. -L., Primavesi F., Rodrigeuz-Lopez M., Formisano G., Delogu D., Umar M., Elisa S., Del Basso C., d'Alessandro A., Sandri G. B. L., Menna M. P., De Simone B., al-Najami I., Curro G., Hila J., Quaresima S., Cervellera M., Sanberg J., Cestaro G., Capuano M., Ammendola M., Pinotti E., Palomba G., Tonini V., Baiocchi G. L., Saraceno F., Calini G., Reccia I., Dasari B. V. M., Poillucci G., Frontali A., Marconi M., Bertilone E., Basile E., Toneto M. G., Coletta D., Cacciaguerra A. B., Umar Younis M., Merlini D. A., Julianov A., Harish N. L., Morelli L., Marone M., Lo Conte D., D'Ugo S., D'Acapito F., Saroglu A., Santambrogio R., Giuffrida M., Furbetta N., Lopez-Lopez V., Panyko A., Romano F., Murillo G. A. A., Spartalis M., Spartalis E., Castaldi A., Koh P. S., Koong J. K., Santiago M. J. C., Grazi G. L., Martinez-Mier G., Beatriz D. A. -A., Gkekas I., Ioannidis O., Lujan S. A. W., Carneros V. J. E., Madrid F., Baroffio P., Rashid A. -S., Irkorucu O., Ros E. P. N., Perez-Bertolez S., Schizas D., Machain G. M., Altinel Y., Veroux M., Corallino D., Lorenzin D., Negoi I., Barabi-no M., Piccino M., Grossi U., Fernandez A. J. G., Saeidi S., Maritato S., Picco-lo G., Serradilla-Martin M., Esposito G., Albanesi F., Lammel-Lindemann J., Libia, A, Podda, M, Di Martino, M, Pata, F, Pellino, G, Di Saverio, S, Anselmo, A, Muttillo, E, De Pastena, M, Campanile, F, Ielpo, B, Spampinato, M, Guerrieri, M, Agresta, F, Cuccurullo, D, Sartori, A, D'Ambrosio, G, Anania, G, Agrusa, A, Allaix, M, Balla, A, Botteri, E, Bracale, U, Ceccarelli, G, Milone, M, Moretto, G, Muttillo, I, Perrotta, N, Pirozzi, F, Ortenzi, M, Ioannidis, A, Stavrou, G, Gica, N, Benzoni, E, Rosa, F, Visag-Castillo, V, Award, S, Machairas, N, Manrique, M, Marino, M, De Nobili, G, Sira-gusa, L, Iossa, A, de Santibanes, M, Lisi, G, De Luca, A, Giuliani, A, Perra, T, Porcu, A, Cillara, N, Giordano, A, Laureiro, Z, Papa, M, Clementi, M, Tamini, N, Soreide, K, Mazzarella, G, Pio, L, Dopazo, C, Argenio, G, An-nechiarico, M, Andreuccetti, J, Calvo, M, Cinardi, N, Angelico, R, Nari, G, Saldino, E, Gazia, C, Anis, B, Machian, G, Romic, I, Bellido-luque, J, Pandanapoyana, S, Roscio, F, Pattaccini, G, Frazzetta, G, Lim, R, Delvecchio, A, Primavesi, F, Rodrigeuz-Lopez, M, Formisano, G, Delogu, D, Umar, M, Elisa, S, Del Basso, C, D'Alessandro, A, Sandri, G, Menna, M, De Simone, B, al-Najami, I, Curro, G, Hila, J, Quaresima, S, Cervellera, M, Sanberg, J, Cestaro, G, Capuano, M, Ammendola, M, Pinotti, E, Palomba, G, Tonini, V, Baiocchi, G, Saraceno, F, Calini, G, Reccia, I, Dasari, B, Poillucci, G, Frontali, A, Marconi, M, Bertilone, E, Basile, E, Toneto, M, Coletta, D, Cacciaguerra, A, Umar Younis, M, Merlini, D, Julianov, A, Harish, N, Morelli, L, Marone, M, Lo Conte, D, D'Ugo, S, D'Acapito, F, Saroglu, A, Santambrogio, R, Giuffrida, M, Furbetta, N, Lopez-Lopez, V, Panyko, A, Romano, F, Murillo, G, Spartalis, M, Spartalis, E, Castaldi, A, Koh, P, Koong, J, Santiago, M, Grazi, G, Martinez-Mier, G, Beatriz, D, Gkekas, I, Ioannidis, O, Lujan, S, Carneros, V, Madrid, F, Baroffio, P, Rashid, A, Irkorucu, O, Ros, E, Perez-Bertolez, S, Schizas, D, Machain, G, Altinel, Y, Veroux, M, Corallino, D, Lorenzin, D, Negoi, I, Barabi-no, M, Piccino, M, Grossi, U, Fernandez, A, Saeidi, S, Maritato, S, Picco-lo, G, Serradilla-Martin, M, Esposito, G, Albanesi, F, Lammel-Lindemann, J, Libia A., Podda M., Di Martino M., Pata F., Pellino G., Di Saverio S., Anselmo A., Muttillo E. M., De Pastena M., Campanile F. C., Ielpo B., Spampinato M. G., Guerrieri M., Agresta F., Cuccurullo D., Sartori A., D'Ambrosio G., Anania G., Agrusa A., Allaix M. E., Balla A., Botteri E., Bracale U., Ceccarelli G., Milone M., Moretto G., Muttillo I., Perrotta N., Pirozzi F., Ortenzi M., Ioannidis A., Stavrou G., Gica N., Benzoni E., Rosa F., Visag-Castillo V., Award S. S., Machairas N., Manrique M. M., Marino M., De Nobili G., Sira-gusa L., Iossa A., de Santibanes M., Lisi G., De Luca A., Giuliani A., Perra T., Porcu A., Cillara N., Giordano A., Laureiro Z. L., Papa M. V., Clementi M., Tamini N., Soreide K., Mazzarella G., Pio L., Dopazo C., Argenio G., An-nechiarico M., Andreuccetti J., Calvo M. P., Cinardi N., Angelico R., Nari G. A., Saldino E., Gazia C., Anis B., Machian G. M., Romic I., Bellido-luque J., Pandanapoyana S., Roscio F., Pattaccini G. C., Frazzetta G., Lim R., Delvecchio A. -L., Primavesi F., Rodrigeuz-Lopez M., Formisano G., Delogu D., Umar M., Elisa S., Del Basso C., d'Alessandro A., Sandri G. B. L., Menna M. P., De Simone B., al-Najami I., Curro G., Hila J., Quaresima S., Cervellera M., Sanberg J., Cestaro G., Capuano M., Ammendola M., Pinotti E., Palomba G., Tonini V., Baiocchi G. L., Saraceno F., Calini G., Reccia I., Dasari B. V. M., Poillucci G., Frontali A., Marconi M., Bertilone E., Basile E., Toneto M. G., Coletta D., Cacciaguerra A. B., Umar Younis M., Merlini D. A., Julianov A., Harish N. L., Morelli L., Marone M., Lo Conte D., D'Ugo S., D'Acapito F., Saroglu A., Santambrogio R., Giuffrida M., Furbetta N., Lopez-Lopez V., Panyko A., Romano F., Murillo G. A. A., Spartalis M., Spartalis E., Castaldi A., Koh P. S., Koong J. K., Santiago M. J. C., Grazi G. L., Martinez-Mier G., Beatriz D. A. -A., Gkekas I., Ioannidis O., Lujan S. A. W., Carneros V. J. E., Madrid F., Baroffio P., Rashid A. -S., Irkorucu O., Ros E. P. N., Perez-Bertolez S., Schizas D., Machain G. M., Altinel Y., Veroux M., Corallino D., Lorenzin D., Negoi I., Barabi-no M., Piccino M., Grossi U., Fernandez A. J. G., Saeidi S., Maritato S., Picco-lo G., Serradilla-Martin M., Esposito G., Albanesi F., and Lammel-Lindemann J.

Abstract

Despite the increasing trend in liver resections for non-colorectal non-neuroendocrine liver metastases (NCNNLM), the role of surgery for these liver malignancies is still debated. Registries are an essential, reliable tool for assessing epidemiology, diagnosis, and therapeutic approach in a single hub, especially when data are dispersive and inconclusive, as in our case. The dissemination of this preliminary survey would allow us to understand if the creation of an International Registry is a viable option, while still offering a snapshot on this issue, investigating clinical practices worldwide. The steering committee designed an online questionnaire with Google Forms, which consisted of 37 questions, and was open from October 5th, 2022, to November 30th, 2022. It was disseminated using social media and mailing lists of the Italian Society of Endoscopic Surgery and New Technologies (SICE), the Association of Italian Surgeons in Europe (ACIE), and the Spanish Chapter of the American College of Surgeons (ACS). Overall, 141 surgeons (approximately 18% of the total invitations sent) from 27 countries on four continents participated in the survey. Most respondents worked in general surgery units (62%), performing less than 50 liver resections/year (57%). A multidisciplinary discussion was currently performed to validate surgical indications for NCNNLM in 96% of respondents. The most commonly adopted selection criteria were liver resectability, RECIST criteria, and absence of extrahepatic disease. Primary tumors were generally of gastrointestinal (42%), breast (31%), and pancreaticobiliary origin (13%). The most common interventions were parenchymal-sparing resections (51% of respondents) of metachronous metastases with an open approach. Major post-operative complications (Clavien–Dindo > 2) occurred in up to 20% of the procedures, according to 44% of respondents. A subset analysis of data from high-volume centers (> 100 cases/year) showed lower post-operative com

Published
2024

2. Defining Global Benchmarks for Laparoscopic Liver Resections: An International Multicenter Study

Author

Goh, B. K. P., Han, H. -S., Chen, K. -H., Chua, D. W., Chan, C. -Y., Cipriani, F., Aghayan, D. L., Fretland, A. A., Sijberden, J., D'Silva, M., Siow, T. F., Kato, Y., Lim, C., Nghia, P. P., Herman, P., Marino, M. V., Mazzaferro, V., Chiow, A. K. H., Sucandy, I., Ivanecz, A., Choi, S. H., Lee, J. H., Gastaca, M., Vivarelli, M., Giuliante, Felice, Ruzzenente, A., Yong, C. -C., Yin, M., Chen, Z., Fondevila, C., Efanov, M., Rotellar, F., Choi, G. -H., Campos, R. R., Wang, X., Sutcliffe, R. P., Pratschke, J., Lai, E., Chong, C. C., D'Hondt, M., Monden, K., Lopez-Ben, S., Coelho, F. F., Kingham, T. P., Liu, R., Long, T. C. D., Ferrero, A., Sandri, G. B. L., Saleh, M., Cherqui, D., Scatton, O., Soubrane, O., Wakabayashi, G., Troisi, R. I., Cheung, T. -T., Sugioka, A., Hilal, M. A., Fuks, D., Edwin, B., Aldrighetti, L., Syn, N., Prieto, M., Schotte, H., De Meyere, C., Krenzien, F., Schmelzle, M., Lee, K. -F., Salimgereeva, D., Alikhanov, R., Lee, L. -S., Jang, J. Y., Kojima, M., Ghotbi, J., Kruger, J. A. P., Lopez-Lopez, V., Valle, B. D., Casellas I Robert, M., Mishima, K., Montalti, R., Giglio, M., Mazzotta, A., Lee, B., Wang, H. -P., Pascual, F., Kadam, P., Tang, C. -N., Yu, S., Ardito, Francesco, Vani, S., Giustizieri, U., Citterio, D., Mocchegiani, F., Ettorre, G. M., Colasanti, M., Guzman, Y., Giuliante F. (ORCID:0000-0001-9517-8220), Ardito F. (ORCID:0000-0003-1596-2862), Goh, B. K. P., Han, H. -S., Chen, K. -H., Chua, D. W., Chan, C. -Y., Cipriani, F., Aghayan, D. L., Fretland, A. A., Sijberden, J., D'Silva, M., Siow, T. F., Kato, Y., Lim, C., Nghia, P. P., Herman, P., Marino, M. V., Mazzaferro, V., Chiow, A. K. H., Sucandy, I., Ivanecz, A., Choi, S. H., Lee, J. H., Gastaca, M., Vivarelli, M., Giuliante, Felice, Ruzzenente, A., Yong, C. -C., Yin, M., Chen, Z., Fondevila, C., Efanov, M., Rotellar, F., Choi, G. -H., Campos, R. R., Wang, X., Sutcliffe, R. P., Pratschke, J., Lai, E., Chong, C. C., D'Hondt, M., Monden, K., Lopez-Ben, S., Coelho, F. F., Kingham, T. P., Liu, R., Long, T. C. D., Ferrero, A., Sandri, G. B. L., Saleh, M., Cherqui, D., Scatton, O., Soubrane, O., Wakabayashi, G., Troisi, R. I., Cheung, T. -T., Sugioka, A., Hilal, M. A., Fuks, D., Edwin, B., Aldrighetti, L., Syn, N., Prieto, M., Schotte, H., De Meyere, C., Krenzien, F., Schmelzle, M., Lee, K. -F., Salimgereeva, D., Alikhanov, R., Lee, L. -S., Jang, J. Y., Kojima, M., Ghotbi, J., Kruger, J. A. P., Lopez-Lopez, V., Valle, B. D., Casellas I Robert, M., Mishima, K., Montalti, R., Giglio, M., Mazzotta, A., Lee, B., Wang, H. -P., Pascual, F., Kadam, P., Tang, C. -N., Yu, S., Ardito, Francesco, Vani, S., Giustizieri, U., Citterio, D., Mocchegiani, F., Ettorre, G. M., Colasanti, M., Guzman, Y., Giuliante F. (ORCID:0000-0001-9517-8220), and Ardito F. (ORCID:0000-0003-1596-2862)

Abstract

Objective: To establish global benchmark outcomes indicators after laparoscopic liver resections (L-LR). Background: There is limited published data to date on the best achievable outcomes after L-LR. Methods: This is a post hoc analysis of a multicenter database of 11,983 patients undergoing L-LR in 45 international centers in 4 continents between 2015 and 2020. Three specific procedures: left lateral sectionectomy (LLS), left hepatectomy (LH), and right hepatectomy (RH) were selected to represent the 3 difficulty levels of L-LR. Fifteen outcome indicators were selected to establish benchmark cutoffs. Results: There were 3519 L-LR (LLS, LH, RH) of which 1258 L-LR (40.6%) cases performed in 34 benchmark expert centers qualified as low-risk benchmark cases. These included 659 LLS (52.4%), 306 LH (24.3%), and 293 RH (23.3%). The benchmark outcomes established for operation time, open conversion rate, blood loss ≥500 mL, blood transfusion rate, postoperative morbidity, major morbidity, and 90-day mortality after LLS, LH, and RH were 209.5, 302, and 426 minutes; 2.1%, 13.4%, and 13.0%; 3.2%, 20%, and 47.1%; 0%, 7.1%, and 10.5%; 11.1%, 20%, and 50%; 0%, 7.1%, and 20%; and 0%, 0%, and 0%, respectively. Conclusions: This study established the first global benchmark outcomes for L-LR in a large-scale international patient cohort. It provides an up-to-date reference regarding the "best achievable" results for L-LR for which centers adopting L-LR can use as a comparison to enable an objective assessment of performance gaps and learning curves.

Published
2023

3. Defining Global Benchmarks for Laparoscopic Liver Resections: An International Multicenter Study

Author

Goh, B. K. P., Han, H. -S., Chen, K. -H., Chua, D. W., Chan, C. -Y., Cipriani, F., Aghayan, D. L., Fretland, A. A., Sijberden, J., D'Silva, M., Siow, T. F., Kato, Y., Lim, C., Nghia, P. P., Herman, P., Marino, M. V., Mazzaferro, V., Chiow, A. K. H., Sucandy, I., Ivanecz, A., Choi, S. H., Lee, J. H., Gastaca, M., Vivarelli, M., Giuliante, Felice, Ruzzenente, A., Yong, C. -C., Yin, M., Chen, Z., Fondevila, C., Efanov, M., Rotellar, F., Choi, G. -H., Campos, R. R., Wang, X., Sutcliffe, R. P., Pratschke, J., Lai, E., Chong, C. C., D'Hondt, M., Monden, K., Lopez-Ben, S., Coelho, F. F., Kingham, T. P., Liu, R., Long, T. C. D., Ferrero, A., Sandri, G. B. L., Saleh, M., Cherqui, D., Scatton, O., Soubrane, O., Wakabayashi, G., Troisi, R. I., Cheung, T. -T., Sugioka, A., Hilal, M. A., Fuks, D., Edwin, B., Aldrighetti, L., Syn, N., Prieto, M., Schotte, H., De Meyere, C., Krenzien, F., Schmelzle, M., Lee, K. -F., Salimgereeva, D., Alikhanov, R., Lee, L. -S., Jang, J. Y., Kojima, M., Ghotbi, J., Kruger, J. A. P., Lopez-Lopez, V., Valle, B. D., Casellas I Robert, M., Mishima, K., Montalti, R., Giglio, M., Mazzotta, A., Lee, B., Wang, H. -P., Pascual, F., Kadam, P., Tang, C. -N., Yu, S., Ardito, Francesco, Vani, S., Giustizieri, U., Citterio, D., Mocchegiani, F., Ettorre, G. M., Colasanti, M., Guzman, Y., Goh, Brian K P, Han, Ho-Seong, Chen, Kuo-Hsin, Chua, Darren W, Chan, Chung-Yip, Cipriani, Federica, Aghayan, Davit L, Fretland, Asmund A, Sijberden, Jasper, D'Silva, Mizelle, Siow, Tiing Foong, Kato, Yutaro, Lim, Chetana, Nghia, Phan Phuoc, Herman, Paulo, Marino, Marco V, Mazzaferro, Vincenzo, Chiow, Adrian K H, Sucandy, Iswanto, Ivanecz, Arpad, Choi, Sung Hoon, Lee, Jae Hoon, Gastaca, Mikel, Vivarelli, Marco, Giuliante, Felice, Ruzzenente, Andrea, Yong, Chee-Chien, Yin, Mengqui, Chen, Zewei, Fondevila, Constantino, Efanov, Mikhail, Rotellar, Fernando, Choi, Gi-Hong, Campos, Ricardo R, Wang, Xiaoying, Sutcliffe, Robert P, Pratschke, Johann, Lai, Eric, Chong, Charing C, D'Hondt, Mathieu, Monden, Kazuteru, Lopez-Ben, Santiago, Coelho, Fabricio F, Kingham, Thomas Peter, Liu, Rong, Long, Tran Cong Duy, Ferrero, Alessandro, Sandri, Giovanni B Levi, Saleh, Mansour, Cherqui, Daniel, Scatton, Olivier, Soubrane, Olivier, Wakabayashi, Go, Troisi, Roberto I, Cheung, Tan-To, Sugioka, Atsushi, Hilal, Mohammad Abu, Fuks, David, Edwin, Bjørn, and Aldrighetti, Luca

Subjects
benchmark, hepatectomy, quality assessment, Settore MED/18 - CHIRURGIA GENERALE, minimally invasive, Surgery, laparoscopic liver resection, global
Abstract

To establish global benchmark outcomes indicators after laparoscopic liver resections (L-LR).There is limited published data to date on the best achievable outcomes after L-LR.This is a post hoc analysis of a multicenter database of 11,983 patients undergoing L-LR in 45 international centers in 4 continents between 2015 and 2020. Three specific procedures: left lateral sectionectomy (LLS), left hepatectomy (LH), and right hepatectomy (RH) were selected to represent the 3 difficulty levels of L-LR. Fifteen outcome indicators were selected to establish benchmark cutoffs.There were 3519 L-LR (LLS, LH, RH) of which 1258 L-LR (40.6%) cases performed in 34 benchmark expert centers qualified as low-risk benchmark cases. These included 659 LLS (52.4%), 306 LH (24.3%), and 293 RH (23.3%). The benchmark outcomes established for operation time, open conversion rate, blood loss ≥500 mL, blood transfusion rate, postoperative morbidity, major morbidity, and 90-day mortality after LLS, LH, and RH were 209.5, 302, and 426 minutes; 2.1%, 13.4%, and 13.0%; 3.2%, 20%, and 47.1%; 0%, 7.1%, and 10.5%; 11.1%, 20%, and 50%; 0%, 7.1%, and 20%; and 0%, 0%, and 0%, respectively.This study established the first global benchmark outcomes for L-LR in a large-scale international patient cohort. It provides an up-to-date reference regarding the "best achievable" results for L-LR for which centers adopting L-LR can use as a comparison to enable an objective assessment of performance gaps and learning curves.

Published
2022

4. Technical feasibility and short-term outcomes of laparoscopic isolated caudate lobe resection: an IgoMILS (Italian Group of Minimally Invasive Liver Surgery) registry-based study

Author

Ruzzenente, A, Ciangherotti, A, Aldrighetti, L, Ettorre, G, De Carlis, L, Ferrero, A, Dalla Valle, R, Tisone, G, Guglielmi, A, Ratti, F, Gringeri, E, Russolillo, N, Campagnaro, T, Conci, S, Sandri, G, Ardito, F, Boggi, U, Gruttadauria, S, Vigano, L, Di Benedetto, F, Rossi, G, Berti, S, Ceccarelli, G, Vincenti, L, Cillo, U, Giuliante, F, Mazzaferro, V, Jovine, E, Calise, F, Belli, G, Zamboni, F, Coratti, A, Mezzatesta, P, Santambrogio, R, Navarra, G, Giuliani, A, Ferla, F, Pinna, A, Parisi, A, Colledan, M, Slim, A, Antonucci, A, Grazi, G, Frena, A, Sgroi, G, Brolese, A, Morelli, L, Floridi, A, Patriti, A, Veneroni, L, Boni, L, Maida, P, Griseri, G, Filauro, M, Guerriero, S, Romito, R, Tedeschi, U, Zimmitti, G, Ruzzenente A., Ciangherotti A., Aldrighetti L., Ettorre G. M., De Carlis L., Ferrero A., Dalla Valle R., Tisone G., Guglielmi A., Ratti F., Gringeri E., Russolillo N., Campagnaro T., Conci S., Sandri G. B. L., Ardito F., Boggi U., Gruttadauria S., Vigano L., Di Benedetto F., Rossi G. E., Berti S., Ceccarelli G., Vincenti L., Cillo U., Giuliante F., Mazzaferro V., Jovine E., Calise F., Belli G., Zamboni F., Coratti A., Mezzatesta P., Santambrogio R., Navarra G., Giuliani A., Ferla F., Pinna A. D., Parisi A., Colledan M., Slim A., Antonucci A., Grazi G. L., Frena A., Sgroi G., Brolese A., Morelli L., Floridi A., Patriti A., Veneroni L., Boni L., Maida P., Griseri G., Filauro M., Guerriero S., Romito R., Tedeschi U., Zimmitti G., Ruzzenente, A, Ciangherotti, A, Aldrighetti, L, Ettorre, G, De Carlis, L, Ferrero, A, Dalla Valle, R, Tisone, G, Guglielmi, A, Ratti, F, Gringeri, E, Russolillo, N, Campagnaro, T, Conci, S, Sandri, G, Ardito, F, Boggi, U, Gruttadauria, S, Vigano, L, Di Benedetto, F, Rossi, G, Berti, S, Ceccarelli, G, Vincenti, L, Cillo, U, Giuliante, F, Mazzaferro, V, Jovine, E, Calise, F, Belli, G, Zamboni, F, Coratti, A, Mezzatesta, P, Santambrogio, R, Navarra, G, Giuliani, A, Ferla, F, Pinna, A, Parisi, A, Colledan, M, Slim, A, Antonucci, A, Grazi, G, Frena, A, Sgroi, G, Brolese, A, Morelli, L, Floridi, A, Patriti, A, Veneroni, L, Boni, L, Maida, P, Griseri, G, Filauro, M, Guerriero, S, Romito, R, Tedeschi, U, Zimmitti, G, Ruzzenente A., Ciangherotti A., Aldrighetti L., Ettorre G. M., De Carlis L., Ferrero A., Dalla Valle R., Tisone G., Guglielmi A., Ratti F., Gringeri E., Russolillo N., Campagnaro T., Conci S., Sandri G. B. L., Ardito F., Boggi U., Gruttadauria S., Vigano L., Di Benedetto F., Rossi G. E., Berti S., Ceccarelli G., Vincenti L., Cillo U., Giuliante F., Mazzaferro V., Jovine E., Calise F., Belli G., Zamboni F., Coratti A., Mezzatesta P., Santambrogio R., Navarra G., Giuliani A., Ferla F., Pinna A. D., Parisi A., Colledan M., Slim A., Antonucci A., Grazi G. L., Frena A., Sgroi G., Brolese A., Morelli L., Floridi A., Patriti A., Veneroni L., Boni L., Maida P., Griseri G., Filauro M., Guerriero S., Romito R., Tedeschi U., and Zimmitti G.

Abstract

Background: Although isolated caudate lobe (CL) liver resection is not a contraindication for minimally invasive liver surgery (MILS), feasibility and safety of the procedure are still poorly investigated. To address this gap, we evaluate data on the Italian prospective maintained database on laparoscopic liver surgery (IgoMILS) and compare outcomes between MILS and open group. Methods: Perioperative data of patients with malignancies, as colorectal liver metastases (CRLM), hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), non-colorectal liver metastases (NCRLM) and benign liver disease, were retrospectively analyzed. A propensity score matching (PSM) analysis was performed to balance the potential selection bias for MILS and open group. Results: A total of 224 patients were included in the study, 47 and 177 patients underwent MILS and open isolated CL resection, respectively. The overall complication rate was comparable between the two groups; however, severe complication rate (Dindo–Clavien grade ≥ 3) was lower in the MILS group (0% versus 6.8%, P = ns). In-hospital mortality was 0% in both groups and mean hospital stay was significantly shorter in the MILS group (P = 0.01). After selection of 42 MILS and 43 open CL resections by PSM analysis, intraoperative and postoperative outcomes remained similar except for the hospital stay which was not significantly shorter in MILS group. Conclusions: This multi-institutional cohort study shows that MILS CL resection is feasible and safe. The surgical procedure can be technically demanding compared to open resection, whereas good perioperative outcomes can be achieved in highly selected patients.

Published
2022

5. Technical feasibility and short-term outcomes of laparoscopic isolated caudate lobe resection: an IgoMILS (Italian Group of Minimally Invasive Liver Surgery) registry-based study

Author

Ruzzenente A., Ciangherotti A., Aldrighetti L., Ettorre G. M., De Carlis L., Ferrero A., Dalla Valle R., Tisone G., Guglielmi A., Ratti F., Gringeri E., Russolillo N., Campagnaro T., Conci S., Sandri G. B. L., Ardito F., Boggi U., Gruttadauria S., Vigano L., Di Benedetto F., Rossi G. E., Berti S., Ceccarelli G., Vincenti L., Cillo U., Giuliante F., Mazzaferro V., Jovine E., Calise F., Belli G., Zamboni F., Coratti A., Mezzatesta P., Santambrogio R., Navarra G., Giuliani A., Ferla F., Pinna A. D., Parisi A., Colledan M., Slim A., Antonucci A., Grazi G. L., Frena A., Sgroi G., Brolese A., Morelli L., Floridi A., Patriti A., Veneroni L., Boni L., Maida P., Griseri G., Filauro M., Guerriero S., Romito R., Tedeschi U., Zimmitti G., Ruzzenente, A., Ciangherotti, A., Aldrighetti, L., Ettorre, G. M., De Carlis, L., Ferrero, A., Dalla Valle, R., Tisone, G., Guglielmi, A., Ratti, F., Gringeri, E., Russolillo, N., Campagnaro, T., Conci, S., Sandri, G. B. L., Ardito, F., Boggi, U., Gruttadauria, S., Vigano, L., Di Benedetto, F., Rossi, G. E., Berti, S., Ceccarelli, G., Vincenti, L., Cillo, U., Giuliante, F., Mazzaferro, V., Jovine, E., Calise, F., Belli, G., Zamboni, F., Coratti, A., Mezzatesta, P., Santambrogio, R., Navarra, G., Giuliani, A., Ferla, F., Pinna, A. D., Parisi, A., Colledan, M., Slim, A., Antonucci, A., Grazi, G. L., Frena, A., Sgroi, G., Brolese, A., Morelli, L., Floridi, A., Patriti, A., Veneroni, L., Boni, L., Maida, P., Griseri, G., Filauro, M., Guerriero, S., Romito, R., Tedeschi, U., Zimmitti, G., Ruzzenente, A, Ciangherotti, A, Aldrighetti, L, Ettorre, G, De Carlis, L, Ferrero, A, Dalla Valle, R, Tisone, G, Guglielmi, A, Ratti, F, Gringeri, E, Russolillo, N, Campagnaro, T, Conci, S, Sandri, G, Ardito, F, Boggi, U, Gruttadauria, S, Vigano, L, Di Benedetto, F, Rossi, G, Berti, S, Ceccarelli, G, Vincenti, L, Cillo, U, Giuliante, F, Mazzaferro, V, Jovine, E, Calise, F, Belli, G, Zamboni, F, Coratti, A, Mezzatesta, P, Santambrogio, R, Navarra, G, Giuliani, A, Ferla, F, Pinna, A, Parisi, A, Colledan, M, Slim, A, Antonucci, A, Grazi, G, Frena, A, Sgroi, G, Brolese, A, Morelli, L, Floridi, A, Patriti, A, Veneroni, L, Boni, L, Maida, P, Griseri, G, Filauro, M, Guerriero, S, Romito, R, Tedeschi, U, and Zimmitti, G

Subjects
medicine.medical_specialty, Carcinoma, Hepatocellular, Settore MED/18 - CHIRURGIA GENERALE, Article, NO, Cohort Studies, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Postoperative Complications, Caudate lobe, Open Resection, Internal medicine, medicine, Hepatectomy, Humans, Multi-institutional, Prospective Studies, Registries, Propensity Score, Contraindication, Retrospective Studies, LS7_4, Intrahepatic, business.industry, Carcinoma, Liver Neoplasms, Minimally invasive liver surgery, Hepatocellular, Perioperative, Hepatology, Length of Stay, medicine.disease, Surgery, Settore MED/18, Bile Ducts, Intrahepatic, Bile Duct Neoplasms, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Propensity score matching, Feasibility Studies, 030211 gastroenterology & hepatology, Laparoscopy, Bile Ducts, business, Propensity score matched, Abdominal surgery
Abstract

Background Although isolated caudate lobe (CL) liver resection is not a contraindication for minimally invasive liver surgery (MILS), feasibility and safety of the procedure are still poorly investigated. To address this gap, we evaluate data on the Italian prospective maintained database on laparoscopic liver surgery (IgoMILS) and compare outcomes between MILS and open group. Methods Perioperative data of patients with malignancies, as colorectal liver metastases (CRLM), hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), non-colorectal liver metastases (NCRLM) and benign liver disease, were retrospectively analyzed. A propensity score matching (PSM) analysis was performed to balance the potential selection bias for MILS and open group. Results A total of 224 patients were included in the study, 47 and 177 patients underwent MILS and open isolated CL resection, respectively. The overall complication rate was comparable between the two groups; however, severe complication rate (Dindo–Clavien grade ≥ 3) was lower in the MILS group (0% versus 6.8%, P = ns). In-hospital mortality was 0% in both groups and mean hospital stay was significantly shorter in the MILS group (P = 0.01). After selection of 42 MILS and 43 open CL resections by PSM analysis, intraoperative and postoperative outcomes remained similar except for the hospital stay which was not significantly shorter in MILS group. Conclusions This multi-institutional cohort study shows that MILS CL resection is feasible and safe. The surgical procedure can be technically demanding compared to open resection, whereas good perioperative outcomes can be achieved in highly selected patients.

Published
2021

6. Evidence on reporting guidelines for surgical technique in clinical disciplines: a scoping review protocol

Author

Zhang, K, Ma, Y, Shi, Q, Shen, J, Wu, J, Zhang, X, Jiao, P, Li, G, Tang, X, Petersen, R, Ng, C, Fiorelli, A, Novoa, N, Bedetti, B, Sandri, G, Hochwald, S, Lerut, T, Sihoe, A, Barchi, L, Gilbert, S, Waseda, R, Toker, A, Gonzalez-Rivas, D, Fruscio, R, Scarci, M, Davoli, F, Piessen, G, Qiu, B, Wang, S, Chen, Y, Gao, S, Zhang K., Ma Y., Shi Q., Shen J., Wu J., Zhang X., Jiao P., Li G. S., Tang X., Petersen R. H., Ng C. S. H., Fiorelli A., Novoa N. M., Bedetti B., Sandri G. B. L., Hochwald S., Lerut T., Sihoe A. D. L., Barchi L. C., Gilbert S., Waseda R., Toker A., Gonzalez-Rivas D., Fruscio R., Scarci M., Davoli F., Piessen G., Qiu B., Wang S. D., Chen Y., Gao S., Zhang, K, Ma, Y, Shi, Q, Shen, J, Wu, J, Zhang, X, Jiao, P, Li, G, Tang, X, Petersen, R, Ng, C, Fiorelli, A, Novoa, N, Bedetti, B, Sandri, G, Hochwald, S, Lerut, T, Sihoe, A, Barchi, L, Gilbert, S, Waseda, R, Toker, A, Gonzalez-Rivas, D, Fruscio, R, Scarci, M, Davoli, F, Piessen, G, Qiu, B, Wang, S, Chen, Y, Gao, S, Zhang K., Ma Y., Shi Q., Shen J., Wu J., Zhang X., Jiao P., Li G. S., Tang X., Petersen R. H., Ng C. S. H., Fiorelli A., Novoa N. M., Bedetti B., Sandri G. B. L., Hochwald S., Lerut T., Sihoe A. D. L., Barchi L. C., Gilbert S., Waseda R., Toker A., Gonzalez-Rivas D., Fruscio R., Scarci M., Davoli F., Piessen G., Qiu B., Wang S. D., Chen Y., and Gao S.

Abstract

Background: The reporting of surgical techniques is of mixed quality, with most at a very minimal level. Reporting guidelines that could be applied to guide surgical technique reporting vary in methodology for development, discipline coverage, dimension coverage and detail requested. However, a scoping review that could indicate the gaps and efforts needed in surgical technique reporting guidelines is lacking and warranted. This study aims to design a methodological rigour protocol to guide the development of a scoping review of surgical technique reporting guidelines. Methods: This protocol is designed following the 2020 manual proposed by the Joanna Briggs Institute. To further ensure the soundness of the protocol, we also included multidisciplinary professionals (including methodologists, clinicians, and journal editors) to refine the protocol. Discussion: Seven key steps for developing the scoping review are identified and presented in detail, including (I) identifying the research questions; (II) inclusion criteria; (III) search strategy; (IV) source of evidence selection; (V) data extraction; (VI) analysis of the evidence; and (VII) presentation of the results. Guided by this protocol, the subsequent scoping review will inform us the overview of surgical technique reporting guidelines and precisely guide our direction and next steps in improving surgical technique reporting guidelines. Trial registration: This protocol is not registered as the PROSPERO database only accepts registration of systematic review protocols while does not accept registration of scoping review protocols.

Published
2021

8. Platelets and hepatocellular cancer: Bridging the bench to the clinics

Author

Lai, aEmail Author, Q., Vitale, bEmail Author, A., Manzia, cEmail Author, T. M., Foschi, dEmail Author, F. G., Sandri, eEmail Author, G. B. L., Gambato, bEmail Author, M., Melandro, fEmail Author, F., Russo, bEmail Author, F. P., Miele, gEmail Author, L., Viganò, hEmail Author, L., Burra, bEmail Author, P., Giannini, iEmail Author, E. G., Aliberti, C., Baccarani, U., Bhoori, S., Borzio, M., Brancaccio, G., Cabibbo, G., Casadei, Gardini, Carrai, A., Cillo, P., Conti, U., Cucchetti, F., D’Ambrosio, A., Dell’Unto, R., Dematthaeis, C., Costanzo, Di, G. G., Di Sandro, S., Fucilli, F., Galati, G., Gasbarrini, A., Giuliante, F., Ghinolfi, D., Grieco, A., Gruttaduria, S., Guarino, M., Kostandini, A., Iavarone, M., Lenci, I., Losito, F., Lupo, L. G., Mazzocato, S., Mescoli, C., Miele, L., Morisco, F., Muley, M., Nicolini, D., Persico, M., Pompili, M., Ponziani, F. R., Pravisani, R., Rapaccini, G. L., Rendina, M., Renzulli, M., Rossi, M., Rreka, E., Sacco, R., Sangiovanni, A., Sessa, A., Simonetti, N., Sposito, C., Tortora, R., Trevisani, F., Viganò, M., Villa, E., Vincenzi, V., Violi, P., Associazione Italiana per lo Studio del Fegato (AISF) HCC Special Interest Group, Lai, Q., aEmail Author, Vitale, A., bEmail Author, Manzia, T. M., cEmail Author, Foschi, F. G., dEmail Author, Sandri, G. B. L., eEmail Author, Gambato, M., bEmail Author, Melandro, F., fEmail Author, Russo, F. P., bEmail Author, Miele, L., gEmail Author, Viganò, L., hEmail Author, Burra, P., bEmail Author, Giannini, E. G., iEmail Author, Aliberti, C., Baccarani, U., Bhoori, S., Borzio, M., Brancaccio, G., Cabibbo, G., Casadei, Gardini, A., Carrai, P., Cillo, U., Conti, F., Cucchetti, A., D’Ambrosio, R., Dell’Unto, C., Dematthaei, Di, Costanzo, G., G., Di Sandro, S., Fucilli, F., Galati, G., Gasbarrini, A., Giuliante, F., Ghinolfi, D., Grieco, A., Gruttaduria, S., Guarino, M., Kostandini, A., Iavarone, M., Lenci, I., Losito, F., Lupo, L. G., Mazzocato, S., Mescoli, C., Miele, L., Morisco, F., Muley, M., Nicolini, D., Persico, M., Pompili, M., Ponziani, F. R., Pravisani, R., Rapaccini, G. L., Rendina, M., Renzulli, M., Rossi, M., Rreka, E., Sacco, R., Sangiovanni, A., Sessa, A., Simonetti, N., Sposito, C., Tortora, R., Trevisani, F., Viganò, M., Villa, E., Vincenzi, V., Violi, P., Associazione Italiana per lo Studio del Fegato (AISF) HCC Special Interest, Group, Lai Q., Vitale A., Manzia T.M., Foschi F.G., Sandri G.B.L., Gambato M., Melandro F., Russo F.P., Miele L., Vigano L., Burra P., Giannini E.G., Aglitti A., Aliberti C., Baccarani U., Bhoori S., Borzio M., Brancaccio G., Cabibbo G., Casadei Gardini A., Carrai P., Cillo U., Conti F., Cucchetti A., D'ambrosio R., Dell'unto C., Dematthaeis N., Di Costanzo G.G., Di Sandro S., Fucilli F., Galati G., Gasbarrini A., Giuliante F., Ghinolfi D., Grieco A., Gruttaduria S., Guarino M., Kostandini A., Iavarone M., Lenci I., Losito F., Lupo L.G., Mazzocato S., Mescoli C., Morisco F., Muley M., Nicolini D., Persico M., Pompili M., Ponziani F.R., Pravisani R., Rapaccini G.L., Rendina M., Renzulli M., Rossi M., Rreka E., Sacco R., Sangiovanni A., Sessa A., Simonetti N., Sposito C., Tortora R., Trevisani F., Vigano M., Villa E., Vincenzi V., Violi P., Lai, Q., Vitale, A., Manzia, T. M., Foschi, F. G., Sandri, G. B. L., Gambato, M., Melandro, F., Russo, F. P., Vigano, L., Burra, P., Giannini, E. G., Casadei Gardini, A., Carrai, P., Cillo, U., Conti, F., Cucchetti, A., D'Ambrosio, R., Dell'Unto, C., Dematthaeis, N., Di Costanzo, G. G., and Vigano, M.

Subjects
Cancer Research, Integrins, Platelet-derived growth factor, Endothelium, Settore MED/12 - GASTROENTEROLOGIA, medicine.medical_treatment, Integrin, Review, lcsh:RC254-282, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Platelet-to-lymphocyte ratio, Selectins, Vascular endothelial growth factor, medicine, Platelet, Selectin, business.industry, Growth factor, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Extravasation, Settore MED/01, medicine.anatomical_structure, Oncology, chemistry, Tumor progression, 030220 oncology & carcinogenesis, Cancer research, 030211 gastroenterology & hepatology, business
Abstract

Growing interest is recently being focused on the role played by the platelets in favoring hepatocellular cancer (HCC) growth and dissemination. The present review reports in detail both the experimental and clinical evidence published on this topic. Several growth factors and angiogenic molecules specifically secreted by platelets are directly connected with tumor progression and neo-angiogenesis. Among them, we can list the platelet-derived growth factor, the vascular endothelial growth factor, the endothelial growth factor, and serotonin. Platelets are also involved in tumor spread, favoring endothelium permeabilization and tumor cells' extravasation and survival in the bloodstream. From the bench to the clinics, all of these aspects were also investigated in clinical series, showing an evident correlation between platelet count and size of HCC, tumor biological behavior, metastatic spread, and overall survival rates. Moreover, a better understanding of the mechanisms involved in the platelet-tumor axis represents a paramount aspect for optimizing both current tumor treatment and development of new therapeutic strategies against HCC. Growing interest is recently being focused on the role played by the platelets in favoring hepatocellular cancer (HCC) growth and dissemination. The present review reports in detail both the experimental and clinical evidence published on this topic. Several growth factors and angiogenic molecules specifically secreted by platelets are directly connected with tumor progression and neo-angiogenesis. Among them, we can list the platelet-derived growth factor, the vascular endothelial growth factor, the endothelial growth factor, and serotonin. Platelets are also involved in tumor spread, favoring endothelium permeabilization and tumor cells’ extravasation and survival in the bloodstream. From the bench to the clinics, all of these aspects were also investigated in clinical series, showing an evident correlation between platelet count and size of HCC, tumor biological behavior, metastatic spread, and overall survival rates. Moreover, a better understanding of the mechanisms involved in the platelet–tumor axis represents a paramount aspect for optimizing both current tumor treatment and development of new therapeutic strategies against HCC.

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results