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2. The FAIR Funder pilot programme to make it easy for funders to require and for grantees to produce FAIR Data

Author

Wittenburg, P., Sustkova, H. Pergl, Montesanti, A., Bloemers, S. M., de Waard, S. H., Musen, M. A., Graybeal, J. B., Hettne, K. M., Jacobsen, A., Pergl, R., Hooft, R. W. W., Staiger, C., van Gelder, C. W. G., Knijnenburg, S. L., van Arkel, A. C., Meerman, B., Wilkinson, M. D., Sansone, S-A, Rocca-Serra, P., McQuilton, P., Gonzalez-Beltran, A. N., Aben, G. J. C., Henning, P., Alencar, S., Ribeiro, C., Silva, C. R. L., Sayao, L., Sales, L., Veiga, V., Lima, J., Dib, S., Xavier, P., Murtinho, R., Tendel, J., Schaap, B. F., Brouwer, P. M., Gavai, A. K., Bouzembrak, Y., Marvin, H. J. P., Mons, A., Kuhn, T., Gambardella, A. A., Azevedo, R. de Miranda, Muhonen, V., van der Naald, M., Smit, N. W., Buys, M. J., de Bruin, T. F., Schoots, F., Goodson, H. J. E., Rzepa, H. S., Jeffery, K. G., Shanahan, H. P., Axton, M., Tkachenko, V., Maya, A. D., Meyers, N. K., Conlon, M., Haak, L. L., and Schultes, E. A.

Subjects
Computer Science - Digital Libraries
Abstract

There is a growing acknowledgement in the scientific community of the importance of making experimental data machine findable, accessible, interoperable, and reusable (FAIR). Recognizing that high quality metadata are essential to make datasets FAIR, members of the GO FAIR Initiative and the Research Data Alliance (RDA) have initiated a series of workshops to encourage the creation of Metadata for Machines (M4M), enabling any self-identified stakeholder to define and promote the reuse of standardized, comprehensive machine-actionable metadata. The funders of scientific research recognize that they have an important role to play in ensuring that experimental results are FAIR, and that high quality metadata and careful planning for FAIR data stewardship are central to these goals. We describe the outcome of a recent M4M workshop that has led to a pilot programme involving two national science funders, the Health Research Board of Ireland (HRB) and the Netherlands Organisation for Health Research and Development (ZonMW). These funding organizations will explore new technologies to define at the time that a request for proposals is issued the minimal set of machine-actionable metadata that they would like investigators to use to annotate their datasets, to enable investigators to create such metadata to help make their data FAIR, and to develop data-stewardship plans that ensure that experimental data will be managed appropriately abiding by the FAIR principles. The FAIR Funders design envisions a data-management workflow having seven essential stages, where solution providers are openly invited to participate. The initial pilot programme will launch using existing computer-based tools of those who attended the M4M Workshop., Comment: This is a pre-print of the FAIR Funders pilot, an outcome of the first Metadata for Machines workshop, see: https://www.go-fair.org/resources/go-fair-workshop-series/metadata-for-machines-workshops/. Corresponding author: E. A Schultes, ORCID 0000-0001-8888-635X

Published
2019

4. Broad autism spectrum and obsessive–compulsive symptoms in adults with the fragile X premutation

Author

Schneider, A, Johnston, C, Tassone, F, Sansone, S, Hagerman, RJ, Ferrer, E, Rivera, SM, and Hessl, D

Subjects
Biological Psychology, Psychology, Intellectual and Developmental Disabilities (IDD), Autism, Behavioral and Social Science, Fragile X Syndrome, Brain Disorders, Clinical Research, Pediatric, Mental Health, Neurosciences, Rare Diseases, Mental health, Neurological, Adult, Autism Spectrum Disorder, Female, Fragile X Mental Retardation Protein, Humans, Male, Neurologic Examination, Neuropsychological Tests, Obsessive-Compulsive Disorder, Photic Stimulation, Social Behavior, Young Adult, Social cognition, fragile X premutation, broad autism spectrum phenotype, obsessive-compulsive disorder, obsessive–compulsive disorder, Cognitive Sciences, Clinical Psychology, Applied and developmental psychology, Biological psychology, Clinical and health psychology
Abstract

ObjectiveClinical observations and a limited number of research studies provide evidence that the fragile X premutation may confer risk for autism, executive dysfunction, and psychopathology. The link to autism spectrum symptoms and social cognition deficits with the premutation remains uncertain, and thus was the focus of the present investigation.MethodOur sample included 131 individuals, 42 men/22 women with the FMR1 premutation (mean age = 31.83 ± 8.59 years) with a normal neurological exam, and 48 men/19 women healthy age-matched controls (mean age = 29.48 ± 7.29 years). Individuals completed a comprehensive neuropsychological battery with additional assessments for social cognition, broad autism spectrum, and obsessive-compulsive (OC) symptoms.ResultsPremutation carriers self-reported higher rates of autism-related symptoms (Autism Quotient; p = .001). Among males only, premutation carriers showed more atypical social interaction (p

Published
2016

5. Towards richer descriptions of our collection of genomes and metagenomes

Author

Field, D., Garrity, G, Selengut, J., Sterk, P., Tatusova, T., Thomson, N., Ashburner, M., Boore, J.L., Cochrane, G., Cole, J., de Pamphilus, C., Edwards, R., Faruque, N., Feldman, R., Gray, T., Gurr, S., Haft, D., Hancock, D., Hertz-Fowler, C., Hughes, J., Joint, I., Kane, M., Kennedy, J., Kolker, E., Kyripides, N., Leebens-Mack, J., Lewis, S., Maltsev, N., Markowitz, V., Methe, B., Morrison, N., Nelson, K., Parkhill, J., Sansone, S., Spiers, A., Stevens, R., Swift, P., Taylor, C., Tateno, Y., Tett, T., Turner, S., Ussery, D., Vaughan, B., Whetzel, T., Wilson, G., and Wipat, A.

Subjects
Basic biological sciences, Genomics standardization open-access Genomics Standards Consortium ontologies metadata
Published
2008

6. Making Common Fund data more findable: catalyzing a data ecosystem

Author

Charbonneau, AL, Brady, A, Czajkowski, K, Aluvathingal, J, Canchi, S, Carter, R, Chard, K, Clarke, DJB, Crabtree, J, Creasy, HH, D'Arcy, M, Felix, V, Giglio, M, Gingrich, A, Harris, RM, Hodges, TK, Ifeonu, O, Jeon, M, Kropiwnicki, E, Lim, MCW, Liming, RL, Lumian, J, Mahurkar, AA, Mandal, M, Munro, JB, Nadendla, S, Richter, R, Romano, C, Rocca-Serra, P, Schor, M, Schuler, RE, Tangmunarunkit, H, Waldrop, A, Williams, C, Word, K, Sansone, S-A, Ma'ayan, A, Wagner, R, Foster, I, Kesselman, C, Brown, CT, and White, O

Subjects
Metadata, Good Health and Well Being, Financial Management, Health Informatics, Ecosystem, Computer Science Applications
Abstract

The Common Fund Data Ecosystem (CFDE) has created a flexible system of data federation that enables researchers to discover datasets from across the US National Institutes of Health Common Fund without requiring that data owners move, reformat, or rehost those data. This system is centered on a catalog that integrates detailed descriptions of biomedical datasets from individual Common Fund Programs’ Data Coordination Centers (DCCs) into a uniform metadata model that can then be indexed and searched from a centralized portal. This Crosscut Metadata Model (C2M2) supports the wide variety of data types and metadata terms used by individual DCCs and can readily describe nearly all forms of biomedical research data. We detail its use to ingest and index data from 11 DCCs.

Published
2022

12. ELIXIR and Toxicology: a community in development [version 2; peer review: 2 approved]

Author

Martens, M., Stierum, R., Schymanski, E.L., Evelo, C.T., Aalizadeh, R., Aladjov, H., Arturi, K., Audouze, K., Babica, P., Berka, K., Bessems, J., Blaha, L., Bolton, E.E., Cases, M., Damalas, D.E., Dave, K., Dilger, M., Exner, T., Geerke, D.P., Grafström, R., Gray, A., Hancock, J.M., Hollert, H., Jeliazkova, N., Jennen, D., Jourdan, F., Kahlem, P., Klanova, J., Kleinjans, J., Kondic, T., Kone, B., Lynch, I., Maran, U., Martinez Cuesta, S., Ménager, H., Neumann, S., Nymark, P., Oberacher, H., Ramirez, N., Remy, S., Rocca-Serra, P., Salek, R.M., Sallach, B., Sansone, S.-A., Sanz, F., Sarimveis, H., Sarntivijai, S., Schulze, Tobias, Slobodnik, J., Spjuth, O., Tedds, J., Thomaidis, N., Weber, R.J.M., van Westen, G.J.P., Wheelock, C.E., Williams, A.J., Witters, H., Zdrazil, B., Županič, A., Willighagen, E.L., Martens, M., Stierum, R., Schymanski, E.L., Evelo, C.T., Aalizadeh, R., Aladjov, H., Arturi, K., Audouze, K., Babica, P., Berka, K., Bessems, J., Blaha, L., Bolton, E.E., Cases, M., Damalas, D.E., Dave, K., Dilger, M., Exner, T., Geerke, D.P., Grafström, R., Gray, A., Hancock, J.M., Hollert, H., Jeliazkova, N., Jennen, D., Jourdan, F., Kahlem, P., Klanova, J., Kleinjans, J., Kondic, T., Kone, B., Lynch, I., Maran, U., Martinez Cuesta, S., Ménager, H., Neumann, S., Nymark, P., Oberacher, H., Ramirez, N., Remy, S., Rocca-Serra, P., Salek, R.M., Sallach, B., Sansone, S.-A., Sanz, F., Sarimveis, H., Sarntivijai, S., Schulze, Tobias, Slobodnik, J., Spjuth, O., Tedds, J., Thomaidis, N., Weber, R.J.M., van Westen, G.J.P., Wheelock, C.E., Williams, A.J., Witters, H., Zdrazil, B., Županič, A., and Willighagen, E.L.

Abstract

Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities.

Published
2021

14. A computational framework for complex disease stratification from multiple large-scale datasets

Author

De Meulder, B., Lefaudeux, D., Bansal, A. T., Mazein, A., Chaiboonchoe, A., Ahmed, H., Balaur, I., Saqi, M., Pellet, J., Ballereau, S., Lemonnier, N., Sun, K., Pandis, I., Yang, X., Batuwitage, M., Kretsos, K., van Eyll, J., Bedding, A., Davison, T., Dodson, P., Larminie, C., Postle, A., Corfield, J., Djukanovic, R., Chung, K. F., Adcock, I. M., Guo, Y. -K., Sterk, P. J., Manta, A., Rowe, A., Baribaud, F., Auffray, C., Gibeon, D., Hoda, U., Kuo, S., Meah, S., Meiser, A., Fleming, L. J., Hu, S., Pavlidis, S., Rossios, C., Russel, K., Wiegman, C., Nezhad, A. T., Oehmichen, A., O'Malley, D., Guitton, F., Emam, I., Agapow, P., Rice, P., Miles, S., Elyasigomari, V., Bel, E., Brinkman, P., Dekker, T., Dijkhuis, A., Hashimoto, S., Hekking, P. -P., Lone-Latif, S., Lutter, R., Ravanetti, L., Smids, B., van Aalderen, W., van de Pol, M., van Drunen, K., van Drunen, M., Wagener, A., Zwinderman, K., Adriaens, N., Carusi, A. M., Richard, F., Nogueira, M. M., Taibi, N., Brasier, O., Aliprantis, A., Alving, K., Faulenbach, C., Braun, A., Hohlfeld, J., Krug, N., Badorrek, P., Bakke, P., Berglind, A., Chaleckis, R., Dahlen, B., Delin, I., Gallart, H., Gomez, C., Hedlin, G., Henriksson, E., James, A. J., Kolmert, J., Konradsen, J., Kupczyk, M., Lantz, A. -S., Lazarinis, L., Mathon, C., Middelveld, R., Naz, S., Nordlund, B., Petren, A., Reinke, S., Sjodin, M., Soderman, P., Strandberg, K., Wheelock, C. E., Zetterquist, W., Balgoma, D., Brandsma, J., Burg, D., Dennison, P., Nicholas, B., Schofield, J. P. R., Skipp, P. J., Staykova, D., Tariq, K., Ward, J., Wilson, S. J., Barber, C., Loza, M. J., Bautmans, A., Sandstrom, T., Behndig, A. F., De Alba, J., Beleta, J., Berton, A., de Verdier, M. G., Nihlen, U., Ostling, J., Dalentoft, T., Lindgren, E., Boedigheimer, M. J., Hu, R., Hu, X., Yu, W., Bigler, J., Bonnelykke, K., Thorsen, J., Vising, N., Bisgaard, H., Bochenek, G., Caruso, M., Emma, R., Campagna, D., Thornton, B., Carayannopoulos, L., Gent, J., Manzies-Gow, A., Sogbesan, A., da Purificacao Rocha, P. C., Pedro, J., Chanez, P., Edwards, J., Flood, B., Hudson, V., Kennington, E. J., Metcalf, L., Rahman-Amin, M., Reynolds, L., Roberts, A., Smith, J., Supple, D., Versnel, J., Walker, S., Coleman, C., Hasan, S., Compton, C., Myles, D., Riley, J., Sousa, A. R., Yeyasingham, E., Pennazza, G., Santoninco, M., D'Amico, A., Dahlen, S. -E., de Boer, P., Robberechts, M., De Lepeleire, I., Fitch, N., Garret, T., Wagers, S., Draper, A., Thorngren, J. -O., Ericsson, M., Erpenbeck, V., Kluglich, M., Nething, K., Riemann, K., Schoelch, C., Seibold, W., Sigmund, R., Wald, F., Wetzel, K., Fichtner, K., Erzen, D., Galffy, G., Horvath, I., Szentkereszty, M., Tamasi, L., Fowler, S. J., Krueger, L., Singer, F., Frey, U., Gahlemann, M., Geiser, T., Hewitt, L., Howarth, P., Marouzet, L., Martin, J., Pink, S., Ray, E., Roberts, G., Smith, C., Gove, K., Gozzard, N., Williams, S., Haughney, J., Higgenbottam, T., Matthews, J. G., Holweg, C., Rutgers, M., Kamphuis, J., Kerry, D., Vink, A., Knobel, H., Knowles, R., Shaw, D. E., Smith, K. M., Know, A., Kots, M., Lambrecht, B., Masefield, S., Nilsson, P., Mikus, M., Miralpeix, M., Monk, P., Mores, N., Valente, S., Montuschi, P., Murray, C. S., Musial, J., Pacino, A., Pahus, L., Palkonen, S., Powel, P., Rao, N., Santini, G., Vestbo, J., von Garnier, C., Weiszhart, Z., Woodcock, A., Biryukov, M., Schneider, R., Herzinger, S., Satagopam, V., Gu, W., da Silva, A. B., Tielmann, A., Bergeron, J., Gaudette, A., Silberberg, A., Henderson, D., Hayat, S., Elefsinioti, A., Moltzen, E. K., Harbo, I. S., Birgitte, J., Bratfalean, D., Houston, P., Kisler, B., Capdevila, F. B., Verbeeck, D., Marchetti, G., Rahal, G., Schuermann, H. D., Mazuranok, L., Hendlich, M., Painell'S, L., Marren, D., Martasek, J., Rimell, J., Romacker, M., Braxenthaler, M., Sansone, S. -A., Rocca-Serra, P., Commission of the European Communities, Pulmonology, Graduate School, Experimental Immunology, Paediatric Pulmonology, Ear, Nose and Throat, Epidemiology and Data Science, APH - Methodology, ARD - Amsterdam Reproduction and Development, Consortium, U-Biopred Study Group And The Etriks, Rocca-Serra, P, Sansone, S, De Meulder, Bertrand [0000-0002-2108-7657], and Apollo - University of Cambridge Repository

Subjects
Quality Control, 0301 basic medicine, Computer science, Bioinformatics, Systems biology, Big data, Environmental data, Machine Learning, Set (abstract data type), 03 medical and health sciences, Structural Biology, Modelling and Simulation, Cluster Analysis, U-BIOPRED Study Group and the eTRIKS Consortium, Disease, False Positive Reactions, Cluster analysis, Molecular signatures, Molecular Biology, lcsh:QH301-705.5, ‘Omics data, 'Omics data, business.industry, Systems Biology, Applied Mathematics, 1199 Other Medical And Health Sciences, Data science, 3. Good health, Computer Science Applications, Systems medicine, 030104 developmental biology, lcsh:Biology (General), Feature (computer vision), Modeling and Simulation, Stratification, Scale (map), business, Biomarkers, Research Article
Abstract

Background Multilevel data integration is becoming a major area of research in systems biology. Within this area, multi-‘omics datasets on complex diseases are becoming more readily available and there is a need to set standards and good practices for integrated analysis of biological, clinical and environmental data. We present a framework to plan and generate single and multi-‘omics signatures of disease states. Methods The framework is divided into four major steps: dataset subsetting, feature filtering, ‘omics-based clustering and biomarker identification. Results We illustrate the usefulness of this framework by identifying potential patient clusters based on integrated multi-‘omics signatures in a publicly available ovarian cystadenocarcinoma dataset. The analysis generated a higher number of stable and clinically relevant clusters than previously reported, and enabled the generation of predictive models of patient outcomes. Conclusions This framework will help health researchers plan and perform multi-‘omics big data analyses to generate hypotheses and make sense of their rich, diverse and ever growing datasets, to enable implementation of translational P4 medicine. Electronic supplementary material The online version of this article (10.1186/s12918-018-0556-z) contains supplementary material, which is available to authorized users.

Published
2018
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16. Quality of bowel cleansing in hospitalized patients undergoing colonoscopy: A multicentre prospective regional study

Author

Rotondano, G, Rispo, A, Bottiglieri, Me, De, Luca, L, Lamanda, R, Orsini, L, BRUZZESE, EUGENIA, GALLORO, GIUSEPPE, Romano, M, Miranda, A, Loguercio, C, Esposito, P, NARDONE, GERARDO ANTONIO PIO, COMPARE, DEBORA, Magno, L, Ruggiero, S, Imperatore, N, De, Palma, Gennarelli, N, Cuomo, R, Passananti, V, Cirillo, M, Cattaneo, D, Bozzi, Rm, D'Angelo, V, Marone, P, Riccio, E, DE NUCCI, GERMANA, C, Monastra, S, CARAVELLI, ANTONELLA, Verde, C, Di, Giorgio, P, Giannattasio, F, Capece, G, Taranto, D, De, Seta, M, Spinosa, G, De, Stefano, S, Familiari, V, Cipolletta, L, Bianco, Ma, Sansone, S, Galasso, G, DE COLIBUS, PATRIZIA, Borgheresi, P, Ricco, Antonio, Martorano, M, Gravina, Ag, Marmo, R, Rea, M, Maurano, A, Labianca, O, Colantuoni, E, Iuliano, D, Trovato, C, Fontana, A, Pasquale, L, Morante, A, Perugini, B, Scaglione, G, Mauro, B., BRUZZESE DARIO, Rotondano, G, Rispo, A, Bottiglieri, Me, De, Luca, L, Lamanda, R, Orsini, L, Bruzzese, Eugenia, Galloro, Giuseppe, Romano, M, Miranda, A, Loguercio, C, Esposito, P, Nardone, GERARDO ANTONIO PIO, Compare, Debora, Magno, L, Ruggiero, S, Imperatore, N, De, Palma, Gd, Gennarelli, N, Cuomo, R, Passananti, V, Cirillo, M, Cattaneo, D, Bozzi, Rm, D'Angelo, V, Marone, P, Riccio, E, DE NUCCI, Germana, Monastra, S, Caravelli, Antonella, Verde, C, Di, Giorgio, P, Giannattasio, F, Capece, G, Taranto, D, De, Seta, M, Spinosa, G, De, Stefano, S, Familiari, V, Cipolletta, L, Bianco, Ma, Sansone, S, Galasso, G, DE COLIBUS, Patrizia, Borgheresi, P, Ricco, Antonio, Martorano, M, Gravina, Ag, Marmo, R, Rea, M, Maurano, A, Labianca, O, Colantuoni, E, Iuliano, D, Trovato, C, Fontana, A, Pasquale, L, Morante, A, Perugini, B, Scaglione, G, Mauro, B., Bruzzese, Dario, De Luca, L, Bruzzese, D, Galloro, G, SIED Campania PISCoPO study group, Investigator, Romano, Marco, Loguercio, Carmelina, Nardone, G, Compare, D, De Palma, Gd, De Nucci, C, Caravelli, G, Di Giorgio, P, De Seta, M, De Stefano, S, De Colibus, P, Ricco, G, and Scaglione, G.

Subjects
Male, Multivariate analysis, Hospitalized patients, Colonoscopy, Sex Factor, Gastroenterology, Body Mass Index, Cardiovascular Disease, Outpatients, Prospective Studies, Aged, 80 and over, Chronic constipation, education.field_of_study, medicine.diagnostic_test, Cathartics, Cathartic, Outpatient, Diabetes Mellitu, Middle Aged, Cardiovascular Diseases, Cleansing, Female, Inpatient, Human, Adult, medicine.medical_specialty, Population, Sex Factors, Bowel preparation, Internal medicine, Diabetes mellitus, Preoperative Care, Diabetes Mellitus, medicine, Humans, education, Aged, Inpatients, Hepatology, business.industry, Odds ratio, Hospitalized patient, medicine.disease, Endoscopy, Prospective Studie, Chronic Disease, business, Constipation
Abstract

Background Quality of bowel cleansing in hospitalized patients undergoing colonoscopy is often unsatisfactory. No study has investigated the inpatient or outpatient setting as cause of inadequate cleansing. Aims To assess degree of bowel cleansing in inpatients and outpatients and to identify possible predictors of poor bowel preparation in the two populations. Methods Prospective multicentre study on consecutive colonoscopies in 25 regional endoscopy units. Univariate and multivariate analysis with odds ratio estimation were performed. Results Data from 3276 colonoscopies were analyzed (2178 outpatients, 1098 inpatients). Incomplete colonoscopy due to inadequate cleansing was recorded in 369 patients (11.2%). There was no significant difference in bowel cleansing rates between in- and outpatients in both colonic segments. In the overall population, independent predictors of inadequate cleansing both at the level of right and left colon were: male gender (odds ratio, 1.20 [1.02–1.43] and 1.27 [1.05–1.53]), diabetes mellitus (odds ratio, 2.35 [1.68–3.29] and 2.12 [1.47–3.05]), chronic constipation (odds ratio, 1.60 [1.30–1.97] and 1.55 [1.23–1.94]), incomplete purge intake (odds ratio, 2.36 [1.90–2.94] and 2.11 [1.68–2.65]) and a runway time >12 h (odds ratio, 3.36 [2.40–4.72] and 2.53 [1.74–3.67]). Conclusions We found no difference in the rate of inadequate bowel preparation between hospitalized patients and outpatients.

Published
2015
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17. Multimodal therapy for previously manipulated lesions using EndoRotor.

Author

Rehman, H., Qaddoumi, A., Sansone, S., Zaghloul, M., Khan, H., Baig, F., and Adolfo, P. B.

Subjects
COMBINED modality therapy, ARGON plasmas, ENDOSCOPIC surgery
Abstract

This article discusses the effectiveness and safety of powered endoscopic resection (EndoRotor) treatment for scarred polyps (manipulated lesions) that occur after the treatment of large polyps with conventional endoscopic and/or surgical methods. The study, conducted at Nottingham University Hospitals NHS Trust, included 42 patients who received EndoRotor treatment. The primary outcome was the complete eradication of the polyps, which was achieved in 93% of patients within three treatment sessions. The study concludes that EndoRotor is a safe and effective treatment for scarred polyps, with most patients achieving complete eradication within three sessions. [Extracted from the article]

Published
2024
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19. CDF Central Outer Tracker

Author

Affolder, T, Allspach, D, Ambrose, D, Bialek, J, Bokhari, W, Brozovic, M, Binkley, M, Burkett, K, Byon-Wagner, A, Cogswell, F, Dressnandt, N, Feng, Z, Franklin, M, Galtieri, L, Gerdes, D.W, Greenwood, J, Guarino, V, Guimaraes da Costa, J, Haggerty, R, Hall, C, Heinrich, J, Holloway, A, Jacobi, T, Kephart, K, Khazins, D, Kim, Y.K, Kirby, M, Kononenko, W, Kotwal, A.V, Kraus, J, Liss, T.M, Lockyer, N, Madrak, R, Miao, T, Mukherjee, A, Neu, C, Newcomer, M, Niczyporuk, J.M, Nodulman, L, Orejudous, W, Phillips, T.J, Pitts, K.T, Reigler, W, Richards, R, Rivetta, C, Robertson, W.J, Roser, R, Sadler, L, Sandberg, R, Sansone, S, Schmitt, R, Schultz, K, Shuman, D, Silva, R, Singh, P, Snihur, R, Tamburello, P, Taylor, J, Thurman-Keup, R, Tousignant, D, Ukegawa, F, Van Berg, R, Veramendi, G, Vickey, T, Wacker, J, Wagner, R.L, Weidenbach, R, Wester, W.C, III, Williams, H.H, Wilson, P, Wittich, P, Yagil, A, Yu, I, Yu, S, and Yun, J.C

Published
2004
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26. The center for expanded data annotation and retrieval

Author

Musen, MA, Bean, CA, Cheung, K-H, Dumontier, M, Durante, KA, Gevaert, O, Gonzalez-Beltran, AN, Khatri, P, Kleinstein, SH, O'Connor, MJ, Pouliot, Y, Rocca-Serra, P, Sansone, S-A, Wiser, JA, and The CEDAR Team

Subjects
data curation, Biomedical Research, data collection, Information retrieval, Data element, Data curation, Computer science, Information Storage and Retrieval, Data discovery, Meta Data Services, datasets as topic, Health Informatics, Information repository, United States, Metadata repository, Metadata, standards, Data Mining, Humans, Brief Communications on Big Data, biological ontologies, Datasets as Topic
Abstract

The Center for Expanded Data Annotation and Retrieval is studying the creation of comprehensive and expressive metadata for biomedical datasets to facilitate data discovery, data interpretation, and data reuse. We take advantage of emerging community-based standard templates for describing different kinds of biomedical datasets, and we investigate the use of computational techniques to help investigators to assemble templates and to fill in their values. We are creating a repository of metadata from which we plan to identify metadata patterns that will drive predictive data entry when filling in metadata templates. The metadata repository not only will capture annotations specified when experimental datasets are initially created, but also will incorporate links to the published literature, including secondary analyses and possible refinements or retractions of experimental interpretations. By working initially with the Human Immunology Project Consortium and the developers of the ImmPort data repository, we are developing and evaluating an end-to-end solution to the problems of metadata authoring and management that will generalize to other data-management environments. ? The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Published
2015
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27. BioSharing: Harnessing Metadata Standards for the Data Commons

Author

Sansone, S-A, Gonzalez-Beltran, A, Rocca-Serra, P, McQuilton, P, Izzo, M, Lister, A, and Thurston, M

Subjects
0303 health sciences, 020205 medical informatics, Computer science, business.industry, Big data, Interoperability, Meta Data Services, 02 engineering and technology, Discoverability, Metadata, World Wide Web, 03 medical and health sciences, Annotation, Resource (project management), 0202 electrical engineering, electronic engineering, information engineering, business, 030304 developmental biology
Abstract

The use of community-driven metadata standards, such as minimal information guidelines, terminologies, formats/models, is essential to ensure that data and other digital research outputs are Findable, Accessible, Interoperable, and Reusable, according to the FAIR principles. As with other types of digital assets, metadata standards also need be FAIR. Their discoverability and accessibility is ensured by BioSharing, the most comprehensive resource of metadata standards, interlinked to data repositories and policies, available in the life, environmental and biomedical sciences. With its growing content, endorsements, and collaborative network, BioSharing is part of a larger ecosystem of interoperable resources. Here we describe some of the activities under the USA National Institutes of Health (NIH)’s Big Data to Knowledge (BD2K) Initiative, illustrating how we track the evolution and use of metadata standards and work to connect them to indexes and annotation tools.

Published
2017
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32. The Plates

Author

Borradaile, G. J., Kehlenbeck, M. M., Friedman, M., Higgs, N. G., Morritt, R. F. C., Powell, C. McA., Vernon, R. H., Watkinson, A. J., Bayly, B. M., Mancktelow, N. S., Davies, W., Lincoln, B. Z., Means, W. D., McClay, K. R., Russell-Head, D. S., Wilson, C. J. L., Williams, V. A., Pfiffner, O. A., Steuer, M. R., Cosgrove, J. W., Bradbury, H. J., Harris, A. L., Gray, D. R., Holcombe, R. J., Martin, D., Puppolo, D., Weber, K., Knipe, R. J., White, S. H., Granath, J. W., Gardner, D. A. C., Solé-Sugrañes, L., Maxwell, J. C., Spang, J. H., Oldershaw, A. E., Ghent, E. D., Stout, M. Z., Alvarez, W., Engelder, T., Sansone, S. A., Hancock, P. L., Crook, K. A. W., Dennis, J. G., Wright, T. O., Gill, G., Platt, L. B., Mimran, Y., De Boer, R. B., Nagtegaal, P. J. C., Wright, E. K., Cook, D., Boulter, C. A., Durney, D. W., Seymour, D. B., Beach, A., Ahmad, R., Lebedeva, N. B., Williams, P. R., Williams, P. F., Nickelsen, R. P., Gregg, W. J., Cox, S. F., Etheridge, M. A., Burger, H. R., Bishop, D. G., Kennedy, M. C., Breaks, F. W., Bond, W. D., Finley, S., Bouchez, J.-L., Wenk, H. R., Ainsworth, J., Cclay, K. R., Boudier, F., Nicolas, A., Talbot, C. J., Twombly, G., Wardlaw, N. C., Hudleston, P. J., Kissin, S. A., Heard, H. C., Conaghan, P. J., Maltman, A. J., Bell, T. H., Rubenach, M. J., Moench, R. H., Bates, D. E. B., Poulsen, K. H., Jackson, P. A., Hughes, K. C., Glen, R. A., Burchfiel, B. C., Roberts, D., Simon, R. I., Borradaile, Graham J., editor, Bayly, M. Brian, editor, and Powell, Chris McA., editor

Published
1982
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34. The future of metabolomics in ELIXIR

Author

van Rijswijk, M, Beirnaert, C, Caron, C, Cascante, M, Dominguez, V, Dunn, WB, Ebbels, TMD, Giacomoni, F, Gonzalez-Beltran, A, Hankemeier, T, Haug, K, Izquierdo-Garcia, JL, Jimenez, RC, Jourdan, F, Kale, N, Klapa, MI, Kohlbacher, O, Koort, K, Kultima, K, Le Corguillé, G, Moreno, P, Moschonas, NK, Neumann, S, O'Donovan, C, Reczko, M, Rocca-Serra, P, Rosato, A, Salek, RM, Sansone, S-A, Satagopam, V, Schober, D, Shimmo, R, Spicer, RA, Spjuth, O, Thévenot, EA, Viant, MR, Weber, RJM, Willighagen, EL, Zanetti, G, Steinbeck, C, Dutch Techcentre for Life Sciences [Utrecht], Netherlands Metabolomics Centre, Department of Mathematics and Computer Science, ADReM, University of Antwerp (UA), French Institute of Bioinformatics (ELIXIR-FR), Department of Biochemistry and Molecular Biomedicine, Faculty of Science and Technology, Biochemistry and Molecular Biology, University of Barcelona, Birmingham Metabolomics Training Centre, University of Birmingham, Department of Surgery and Cancer, Imperial College London, Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), MetaboHUB, Oxford e-Research Centre, University of Oxford, Leiden Academic Centre for Drug Research (LACDR), Universiteit Leiden, European Bioinformatics Institute [Hinxton] (EMBL-EBI), EMBL Heidelberg, Centro Nacional de Investigaciones Cardiovasculares, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), ELIXIR Hub [Cambridge], Métabolisme et Xénobiotiques (ToxAlim-MeX), ToxAlim (ToxAlim), Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT), Forth ICE-HT, Institute of Chemical Engineering Sciences, Foundation for Research and Technology - Hellas (FORTH), Max Planck Institute for Developmental Biology, Max-Planck-Gesellschaft, Department of Computer Science, Duke University [Durham], Center for Bioinformatics, University of Tübingen, The Centre of Excellence in Neural and Behavioural Sciences, Tallinn University, School of Natural Sciences and Health, Department of Medical Sciences (University of Miyasaki), University of Miyasaki, ABiMS - Informatique et bioinformatique = Analysis and Bioinformatics for Marine Science (ABIMS), Fédération de recherche de Roscoff (FR2424), Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS), Department of General Biology, Universidade Federal de Minas Gerais [Belo Horizonte] (UFMG), University of Patras, Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry (IPB), BSRC 'Alexander Fleming', Magnetic Resonance Center/Interuniversity Consortium of Magnetic Resonance Metalloproteins, Università degli Studi di Firenze = University of Florence (UniFI), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg [Luxembourg], Université du Luxembourg (Uni.lu), Department of Pharmaceutical Biosciences, Uppsala University, Laboratoire Sciences des Données et de la Décision (LS2D), Département Métrologie Instrumentation & Information (DM2I), Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Department of Bioinformatics, BiGCaT, Maastricht University [Maastricht], NUTRIM, Data-Intensive Computing, CRS4 Bioinformat, Friedrich-Schiller-Universität = Friedrich Schiller University Jena [Jena, Germany], ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 654241,H2020,H2020-EINFRA-2014-2,PhenoMeNal(2015), European Commission, Unité de Nutrition Humaine - Clermont Auvergne (UNH), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne (UCA), Leiden University, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA), ABiMS - Informatique et bioinformatique = Analysis and Bioinformatics for Marine Science (FR2424), Université Pierre et Marie Curie (Paris 6), Federal University of Minas Gerais Belo Horizonte, University of Patras [Patras], University of Florence (UNIFI), Laboratoire d'analyse des données et d'intelligence des systèmes (LADIS), Laboratoire d'Intégration des Systèmes et des Technologies (LIST), Université Paris-Saclay-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Laboratoire d'Intégration des Systèmes et des Technologies (LIST), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Maastricht University, Friedrich-Schiller-Universität Jena, ANR-11-INBS-0010/11-INBS-0010,METABOHUB,Développement d’une infrastructure française distribuée pour la métabolomique dédiée à l’innovation(2011), Commission of the European Communities, European Molecular Biology Laboratory, Apollo-University Of Cambridge Repository, van Rijswijk, Merlijn [0000-0002-1067-7766], Beirnaert, Charlie [0000-0003-3007-2569], Gonzalez-Beltran, Alejandra [0000-0003-3499-8262], Haug, Kenneth [0000-0003-3168-4145], Jimenez, Rafael C [0000-0001-5404-7670], Kale, Namrata [0000-0002-4255-8104], Klapa, Maria I [0000-0002-2047-3185], Moschonas, Nicholas K [0000-0002-2556-537X], Rosato, Antonio [0000-0001-6172-0368], Salek, Reza M [0000-0001-8604-1732], Sansone, Susanna-Assunta [0000-0001-5306-5690], Schober, Daniel [0000-0001-8014-6648], Spicer, Rachel A [0000-0002-2807-8796], Spjuth, Ola [0000-0002-8083-2864], Thévenot, Etienne A [0000-0003-1019-4577], Willighagen, Egon L [0000-0001-7542-0286], Steinbeck, Christoph [0000-0001-6966-0814], Apollo - University of Cambridge Repository, RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health, Bioinformatica, RS: NUTRIM - R4 - Gene-environment interaction, University of Oxford [Oxford], Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST), Università degli Studi di Firenze = University of Florence [Firenze], Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées

Subjects
0301 basic medicine, databases, Data management, computational workflows, infrastructure en ligne, Cloud computing, Computational biology, Biology, General Biochemistry, Genetics and Molecular Biology, Chemical Biology of the Cell, analyse métabolomique, 03 medical and health sciences, statistical analysis, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], [INFO.INFO-DL]Computer Science [cs]/Digital Libraries [cs.DL], Use case, General Pharmacology, Toxicology and Pharmaceutics, signal processing, computer.programming_language, bioinformatics infrastructure, training, 030102 biochemistry & molecular biology, General Immunology and Microbiology, metabolomics, bioinformatics, distributed computing, cloud, business.industry, cloud computing, pipeline, Articles, General Medicine, Opinion Article, Data science, metabolomics, Open data, Identification (information), 030104 developmental biology, Workflow, multi-omics approaches, Elixir (programming language), [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], business, data standards, computer, Omics technologies
Abstract

We are grateful to the proteomics community for sharing their experiences from their meeting “The future of proteomics in ELIXIR” on March 1–2 2017 in Tübingen, allowing us to build on this and organise our workshop as a one-day event.The meeting was funded by PhenoMeNal, European Commission's Horizon2020 programme, grant agreement number 654241; Metabolomics, the youngest of the major omics technologies, is supported by an active community of researchers and infrastructure developers across Europe. To coordinate and focus efforts around infrastructure building for metabolomics within Europe, a workshop on the "Future of metabolomics in ELIXIR" was organised at Frankfurt Airport in Germany. This one-day strategic workshop involved representatives of ELIXIR Nodes, members of the PhenoMeNal consortium developing an e-infrastructure that supports workflow-based metabolomics analysis pipelines, and experts from the international metabolomics community. The workshop established metabolite identification as the critical area, where a maximal impact of computational metabolomics and data management on other fields could be achieved. In particular, the existing four ELIXIR Use Cases, where the metabolomics community - both industry and academia - would benefit most, and which could be exhaustively mapped onto the current five ELIXIR Platforms were discussed. This opinion article is a call for support for a new ELIXIR metabolomics Use Case, which aligns with and complements the existing and planned ELIXIR Platforms and Use Cases

Published
2017
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35. The Ontology for Biomedical Investigations

Author

Bandrowski, A, Brinkman, R, Brochhausen, M, Brush, MH, Bug, B, Chibucos, MC, Clancy, K, Courtot, M, Derom, D, Dumontier, M, Fan, L, Fostel, J, Fragoso, G, Gibson, F, Gonzalez-Beltran, A, Haendel, MA, He, Y, Heiskanen, M, Hernandez-Boussard, T, Jensen, M, Lin, Y, Lister, AL, Lord, P, Malone, J, Manduchi, E, McGee, M, Morrison, N, Overton, JA, Parkinson, H, Peters, B, Rocca-Serra, P, Ruttenberg, A, Sansone, S-A, Scheuermann, RH, Schober, D, Smith, B, Soldatova, LN, Stoeckert, CJ, Taylor, CF, Torniai, C, Turner, JA, Vita, R, Whetzel, PL, Zheng, J, Xue, Y, and Xue, Y

Subjects
0301 basic medicine, Databases, Factual, Microarrays, Computer science, Interoperability, Social Sciences, lcsh:Medicine, Ontology (information science), Bioinformatics, 0302 clinical medicine, Sociology, Consortia, Medicine and Health Sciences, Psychology, ontologies, lcsh:Science, Data Management, Language, computer.programming_language, Protozoans, Multidisciplinary, Malarial Parasites, Web Ontology Language, Genomics, Semantics, Functional Genomics, 3. Good health, ontology for Biomedical Investigations (OBI), Bioassays and Physiological Analysis, Vertebrates, web ontology language, Ontology, Web resource, Research Article, biomedical investigations, Computer and Information Sciences, Research and Analysis Methods, Basic Formal Ontology, Birds, World Wide Web, Open Biomedical Ontologies, 03 medical and health sciences, Text mining, Ontologies, Parasitic Diseases, Genetics, Animals, Humans, Ontology for Biomedical Investigations, Internet, Metadata, Raptors, business.industry, lcsh:R, Organisms, Cognitive Psychology, Computational Biology, Biology and Life Sciences, Biological Ontologies, Parasitic Protozoans, Owls, 030104 developmental biology, Amniotes, Cognitive Science, lcsh:Q, business, computer, Software, 030217 neurology & neurosurgery, Neuroscience
Abstract

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource (http://obi-ontology.org) providing details on the people, policies, and issues being addressed in association with OBI. The current release of OBI is available at http://purl.obolibrary.org/obo/obi.owl. This work was supported by the National Institute of Allergy and Infectious Diseases (https:// www.niaid.nih.gov/Pages/default.aspx) R01AI081062 to YH, the National Institutes of Health (http://www. nih.gov/) R01GM093132, U01 DK 072473, P41 HG003619 and HHSN272201400030C to CJS, HHSN272201400028C to RHS, HHSN272201200010C and 1U19AI118626 to BP, the California Institute for Regenerative Medicine (https:// www.cirm.ca.gov) GC1R-06673-B to RHS, the National Science Foundation Division of Biological Infrastructure (http://www.nsf.gov) 1458400 to MCC

Published
2016

36. ELIXIR-UK role in bioinformatics training at the national level and across ELIXIR

Author

Larcombe, L., primary, Hendricusdottir, R., additional, Attwood, T.K., additional, Bacall, F., additional, Beard, N., additional, Bellis, L.J., additional, Dunn, W.B., additional, Hancock, J.M., additional, Nenadic, A., additional, Orengo, C., additional, Overduin, B., additional, Sansone, S-A, additional, Thurston, M., additional, Viant, M.R., additional, Winder, C.L., additional, Goble, C.A., additional, Ponting, C.P., additional, and Rustici, G., additional

Published
2017
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40. Meeting Report:'Metagenomics, Metadata and Meta-analysis' (M3) Special Interest Group at ISMB 2009

Author

Hirschman, L., Sterk, P., Field, D., Wooley, J., Cochrane, G., Gilbert, J., Kolker, E., Kyrpides, N., Meyer, F., Mizrachi, I., Nakamura, Y., Sansone, S., Schriml, L., Tatusova, T., White, O., and Yilmaz, P.

Abstract

This report summarizes the M3 Workshop held at the January 2010 Pacific Symposium on Biocomputing. The workshop, organized by Genomic Standards Consortium members, included five contributed talks, a series of short presentations from stakeholders in the genomics standards community, a poster session, and, in the evening, an open discussion session to review current projects and examine future directions for the GSC and its stakeholders.

Published
2015

41. Effect of immunosop_ pressive therapy on patients with inflammatory bowel diseases and hepatitis B or C virus infection

Author

Morisco F, Castiglione F, Rispo A, Stroffolini T, Sansone S, Vitale R, Guarino M, Biancone L, Caruso A, D’Incà R, Marmo R, A. Orlando, L. Donnarumma, S. Camera, Zorzi F, Renna S, Bove V, Tontini G, Vecchi M, Caporaso N., RIEGLER, Gabriele, Morisco, F, Castiglione, F, Rispo, A, Stroffolini, T, Sansone, S, Vitale, R, Guarino, M, Biancone, L, Caruso, A, D’Incà, R, Marmo, R, A., Orlando, Riegler, Gabriele, L., Donnarumma, S., Camera, Zorzi, F, Renna, S, Bove, V, Tontini, G, Vecchi, M, and Caporaso, N.

Subjects
biological agents, HBV reactivation, virus diseases, antiviral, digestive system diseases
Abstract

Viral hepatitis reactivation has been widely reported in patients undergoing immunosuppressive therapy; however, few data are available about the risk of HBV and HCV reactivation in patients with inflammatory bowel disease, receiving immunosuppressive drugs. The aim of our study was to assess the prevalence of HBV and HCV infection in a consecutive series of patients with inflammatory bowel disease and to value the effects of immunosuppressive therapy during the course of the infection. Retrospective observational multicenter study included all consecutive patients with inflammatory bowel disease who have attended seven Italian tertiary referral hospitals in the last decade. A total of 5096 patients were consecutively included: 2485 Crohn’s disease and 2611 Ulcerative Colitis. 30.5% and 29.7% of the patients were investigated for HBV and HCV infection. A total of 30 HBsAg positive, 17 isolated anti-HBc and 60 anti-HCV-positive patients were identified. In all, 20 patients with HBV or HCV infection received immunosuppressive therapy (six HBsAg+; four isolated anti- HBc+ and 10 anti-HCV+). One of six patients showed HBsAg + and one of four isolated anti-HBc+ experienced reactivation of hepatitis. Two of six HBsAg patients received prophylactic therapy with lamivudine. Only one of 10 anti-HCV+ patients showed mild increase in viral load and ALT elevation. Screening procedures for HBV and HCV infection at diagnosis have been underused in patients with inflammatory bowel disease. We confirm the role of immunosuppressive therapy in HBV reactivation, but the impact on clinical course seems to be less relevant than previous reported.

Published
2013

42. Multimodal treatment of constipation: surgery, riabilitation or both?

Author

Brusciano L, Di Stazio C, Del Genio GM, TOLONE, SALVATORE, Sansone S, Lucido F, Verde I, D'Alessandro A, Gili S, Topatino A, Amoroso V, Casalino P, DOCIMO, Ludovico, LIMONGELLI, Paolo, RUGGIERO, Roberto, DOCIMO, Giovanni, Brusciano, L, Di Stazio, C, Limongelli, Paolo, Del Genio, Gm, Tolone, Salvatore, Sansone, S, Lucido, F, Verde, I, D'Alessandro, A, Ruggiero, Roberto, Gili, S, Topatino, A, Amoroso, V, Casalino, P, Docimo, Giovanni, and Docimo, Ludovico

Published
2012

43. GOBLET: the Global Organisation for Bioinformatics Learning, Education and Training

Author

Atwood T.K., Bongcam-Rudloff E., Brazas M.E., Corpas M., Gaudet P., Lewitter F., Mulder N., Palagi P.M., Schneider M.V., van Gelder C.W.G., Attwood T.K., Banag C., Blackford S., Blatter M.C., Brazas M.D., Brooksbank C., Budd A., Charleston M., Christoffels A., Conesa A., Crowe M., Davies A., de Crecy-Lagard V., De Las Rivas J., Doyle M., Edwards R., Facchiano A., Fernandes P., Gaeta B., Heger A., Herringa J., Hughes D., Jimenez R.C., Kille P., Korpelainen E., Kumuthini J., MacLean D., Martinez S.A.R., McGrath A., Michalopoulos I., Ouellette B.F., Pearson W.R., Qi W., Romano P., Rother K., Sansone S-A., Schonbach C., Tastan-Bishop O., Trelles O., Twells R., Via A., Vriend G., Warnow T., Watson M., Westervelt N., and Zanzoni A.

Subjects
Bioinformatics, learning, education, training, QH301-705.5, Computer science, International scale, Big data, Globe, Other Research Radboud Institute for Molecular Life Sciences [Radboudumc 0], ddc:616.07, Training (civil), Cellular and Molecular Neuroscience, Genetics, medicine, Biology (General), Molecular Biology, Curriculum, Ecology, Evolution, Behavior and Systematics, Ecology, business.industry, 4. Education, Outreach, March of Progress, medicine.anatomical_structure, Computational Theory and Mathematics, Modeling and Simulation, Perspective, Stewardship, business
Abstract

Contains fulltext : 155330.pdf (Publisher’s version ) (Open Access) In recent years, high-throughput technologies have brought big data to the life sciences. The march of progress has been rapid, leaving in its wake a demand for courses in data analysis, data stewardship, computing fundamentals, etc., a need that universities have not yet been able to satisfy--paradoxically, many are actually closing "niche" bioinformatics courses at a time of critical need. The impact of this is being felt across continents, as many students and early-stage researchers are being left without appropriate skills to manage, analyse, and interpret their data with confidence. This situation has galvanised a group of scientists to address the problems on an international scale. For the first time, bioinformatics educators and trainers across the globe have come together to address common needs, rising above institutional and international boundaries to cooperate in sharing bioinformatics training expertise, experience, and resources, aiming to put ad hoc training practices on a more professional footing for the benefit of all.

Published
2015
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44. The ATLAS Experiment at the CERN Large Hadron Collider

Author

Aad, G, Bentvelsen, S, Bobbink, G J, Bos, K, Boterenbrood, H, Brouwer, G, Buis, E J, Buskop, J J F, Colijn, A P, Dankers, R, Daum, C, de Boer, R, de Jong, P, Ennes, P, Gosselink, M, Groenstege, H, Hart, R G G, Hartjes, F, Hendriks, P J, Hessey, N P, Jansweijer, P P M, Kieft, G, Klous, S, Kluit, P, Koffeman, E, Koutsman, A, Liebig, W, Limper, M, Linde, F, Luijckx, G, Massaro, G, Muijs, A, Peeters, S J M, Reichold, A, Rewiersma, P, Rijpstra, M, Scholte, R C, Schuijlenburg, H W, Snuverink, J, van der Graaf, H, van der Kraaij, E, Van Eijk, B, van Kesteren, Z, van Vulpen, I, Verkerke, W, Vermeulen, J C, Vreeswijk, M, Werneke, P, Cakir, O, Ciftci, A K, Duran Yildiz, H, Sultanov, S, Turk Cakir, I, Yilmaz, M, Aubert, B, Bazan, A, Beaugiraud, B, Bellachia, F, Berger, N, Blaising, J J, Colas, J, Consonni, M, Delebecque, P, Delsart, P A, Di Ciaccio, L, Dayot, N Dumont>, Elles, S, Ghez, Philippe>, Girard, C G, Gouanere, M, Goy, C, Guillemin, T, Ionescu, G, Jeremie, A, Jezequel, S, Lafaye, R, Laplace, S, Marchand, J F, Massol, N, Neukermans, L, Perrodo, P, Perrot, G, Prast, J, Przysiezniak, H, Sauvage, G, Thion, J, Wingerter-Seez, I, Zitoun, R, Zolnierowski, Y, Baranov, S, Blair, R E, Cranshaw, J, Dawson, J W, Drake, G, Fullana Torregrosa, E, Gieraltowski, G F, Grudzinski, J, Guarino, V J, Hill, D, Hill, N, Karr, K, LeCompte, T, Lim, H, Malon, D, May, E N, Nodulman, L J, Petereit, E, Price, L E, Proudfoot, J, Schlereth, J L, Stanek, R W, Underwood, D G, van Gemmeren, P, Vaniachine, A, Yoshida, R, Zhang, J, Cheu, E, Johns, K A, Lampl, W, Loch, P, Rutherfoord, J P, Savine, A Y, Shaver, L, Shupe, M A, Tompkins, D, Varnes, E W, Alexopoulos, T, Avramidou, R, Dris, M, Filippas, A, Fokitis, M, Gazis, E N, Katsoufis, E, Maltezos, S, Papadopoulou, T, Savva, P, Tsipolitis, G, Tzamariudaki, E, Vlachos, S, Antonaki, A, Arabidze, G, Fassouliotis, D, Giakoumopoulou, V, Giokaris, N, Ioannou, P, Kourkoumelis, C, Manousakis-Katsikakis, A, Nikolopoulos, K, Tzanakos, G, Vellidis, C, Abdinov, O, Aliyev, M, Huseynov, N, Khalilzade, F, Biscarat, C, Blanch, O, Blumenschein, U, Bosman, M, Bravo, S, Casado, M P, Cavalli-Sforza, M, Deluca Silberberg, C, Domingo, E, Dosil, M, Espinal Curull, X, Fiorini, L, Flix, J, Garitaonandia, H, Iglesias Escudero, M C, Korolkov, I, Mir, L M, Verge, L Miralles>, Norniella Francisco, O, Osuna, C, Pacheco Pages, A, Padilla Aranda, C, Park, I, Perez Codina, E, Puigdengoles, C, Dachs, I Riu>, Ruiz, H, Salto Bauza, O, Sanchez Sanchez, C A, Segura, E, Sushkov, S, Vives Vaques, F, Volpi, M, Chen, T, Cheng, S, Feng, C, Han, H, Han, L, He, M, Jiang, Y, Jin, G, Jin, S, Lu, F, Ouyang, Q, Pei, E, Ping, J, Qi, M, Shan, L, Tong, G, Xie, Y, Xu, G, Yang, Y, Yu, X, Zhang, H, Zhang, X, Zheng, S, Zhu, C G, Krstic, J, Milosavljevic, M, Popovic, D S, Reljic, D, Sijacki, D, Simic, L, Vranjes, N, Vudragovic, M, Buanes, T, Eigen, G, Johansen, L G, Kastanas, A, Lipniacka, A, Mohn, B, Sandaker, H, Stugu, B, Tonoyan, A, Kolanoski, H, Kwee, R, Lohse, T, zur Nedden, M, Ambrosini, G, Beck, H P, Borer, K, Ereditato, A, Gjelsten, B K, Haeberli, C, Haug, S, Hess, M, Kabana, S, Kordas, K, Pretzl, K, Thomas, E, Topfel, C, Booth, J R A, Bright-Thomas, P G, Charlton, D G, Curtis, C J, Dowell, J D, Garvey, J, Hillier, S J, Hollins, T I, Homer, R J, Jovanovic, P, Mahout, G, McMahon, T J, Moye, T H, O'Neale, S W, Staley, R J, Thomas, J P, Typaldos, D, Watkins, P M, Watson, A T, Wilson, J A, Woehrling, E, Antonelli, S, Bellagamba, L, Bertin, A, Boscherini, D, Bruni, A, Bruni, G, Bruschi, M, Caforio, D, Corradi, M, De Castro, S, Fabbri, L, Faccioli, P, Giacobbe, B, Giusti, P, Grimaldi, F, Iacobucci, G, Massa, I, Mazzanti, P, Piccinini, M, Polini, A, Sbarra, C, Sbrizzi, A, Semprini-Cesari, N, Spighi, R, Villa, M, Vitale, A, Zoccoli, A, Ackers, M, Brock, I, Cammin, J, Cristinziani, M, Desch, K K, Dietsche, W, Eyring, A, Fischer, P, Fleischmann, S, Geich-Gimbel, C, Grosse-Knetter, J, Honerbach, W, Huegging, F, Karagounis, M, Klute, M, Kokott, T, Lehmacher, M, Loddenkoetter, T, Martinez, G, Mathes, M, Meuser, S, Nderitu, S K, Nunes Hanninger, G, Ockenfels, W, Odenthal, I, Peric, I, Pleier, M A, Prabhu, R, Raith, B, Runolfsson, O, Ruwiedel, C, Schmitz, M, Stockmanns, T, Ta, D, Treis, J, Wermes, N, Wienemann, P, Zendler, C, Ahlen, S P, Butler, J M, Hazen, E, Lewandowska, M, Love, J, Marin, A, Nation, N R, Posch, C, Shank, J T, Whitaker, S P, Yan, Z, Youssef, S P, Bensinger, J R, Blocker, C, Dushkin, A, Hashemi, K, Kirsch, L E, Kotchetkov, D, Schricker, A, Skvorodnev, N, Wellenstein, H, Bednar, P, Bruncko, D, Coss, J, Ferencei, J, Gazo, E, Kladiva, E, Lovas, L, Seman, M, Stavina, P, Strizenec, P, Sykora, I, Tokar, S, Tomasz, F, Zenis, T, Zilka, B, Adams, D L, Armstrong, S R, Assamagan, K, Burns, R, Chan, A, Chen, H, Cunha, A, Damazio, D, Deng, W, Duffin, S, Farrell, J, Gibbard, B, Gordeev, A, Gordon, H, Greenwood, D, Hackenburg, R, Hoffmann, A E, Hover, J, Ito, H, Izen, J M, Junnarkar, S S, Kandasamy, A, Kandasamy, S, Kierstead, J A, Klimentov, A, Lanni, F, Le Vine, M, Lissauer, A, Lou, X, Lynn, D, Ma, H, Maeno, T, Makowiecki, D, Misawa, S, Muller, T R, Nevski, P, Paige, F, Panitkin, S, Park, W, Pate, D, Petti, R, Polychronakos, V, Popescu, R, Purohit, M, Radeka, V, Rahm, D, Rajagopalan, S, Redlinger, G R, Rehak, M, Rescia, S, Sexton, K A, Smith, J, Snyder, S, Sondericker, J, Stumer, I, Takai, H, Tarrade, F, Tcherniatine, V, Undrus, A, Wenaus, T, White, S, Wlodek, T, Yarradoddi, K, Yu, D, Zhao, X, Alexa, C, Badescu, E, Boldea, V, Caprini, I, Caprini, M, Caramarcu, C, Chesneanu, D, Ciubancan, M, Constantinescu, S, Dita, P, Dita, S, Gruse, C, Micu, L, Niculescu, M, Pantea, D, Preda, T, Rotaru, M, Gonzalez Silva, M L, Piegaia, R, Romeo, G, Bieri, M, Komaragiri, J R, O'Neil, D C, Rezaie, E, Schouten, D, Stewart, T D, Vetterli, M C, Benedict, B H, Bold, T, Ciobotaru, M D, Corso-Radu, A, Gough Eschrich, I, Hawkins, D, Kolos, S, Lankford, A J, McCormick, C, Mommsen, R, Murillo Garcia, R, Negri, A, Pier, S, Schernau, M, Stancu, S N, Unel, G, Wheeler-Ellis, S J, Chouridou, S, Dorfan, D E, Dubbs, T, Fadeyev, V, Grillo, A A, Hansl-Kozanecka, T, Litke, A M, Lockman, W S, Nielsen, J, Pequenao, J, Rosenbaum, F, Sadrozinski, H F W, Seiden, A, Spencer, E, Taylor, G, Batley, J R, Brochu, F M, Carter, J R, Frost, J A, Goodrick, M J, Hill, J C, Lester, C G, Munday, D J, Palmer, M J, Parker, M A, Phillips, A W, Robinson, D, Ward, C P, White, M J, Aleksa, M, Amaral, P, Amaral, S P, Amelung, C, Anghinolfi, F, Avolio, G, Bachy, G, Baltasar Dos Santos Pedrosa, F, Baron, S, Poy, A Barriuso>, Batraneanu, S, Battistin, M, Beltramello, O, Berge, D, Bergsma, F, Bertinelli, F, Bitadze, A, Blanchot, G, Bock, R, Bogaerts, J A, Boisvert, V, Bonneau, P, Boosten, M, Bosteels, M, Boyd, J, Braem, A, Bremer, J, Bujor, F, Burckhart, H, Burckhart-Chromek, D, Butin, F, Campana, S, Capeans Garrido, M D M, Cardiel Sas, L, Carli, T, Catinaccio, A, Cattai, A, Cernoch, C, Cerri, A, Chevalley, J L, Cook, J, Cornelissen, T, Da Silva, R, Danielsson, H O, Dannheim, D, Dauvergne, J P, De Oliveira Branco, M, Dell'Acqua, A, Delmastro, M, Delruelle, N, Di Girolamo, B, Di Simone, A, Dittus, F, Dobinson, R, Dobos, D, Dobson, M, Donega, M, Drakoulakos, D, Drevermann, H, Dudarev, A, Dydak, F, Eklund, L M, Ellis, N, Elsing, M, Fabjan, C W, Fabre, C, Farthouat, P, Fassnacht, P, Fedorko, I, Ferrari, P, Flammer, J, Flegel, W, Fonseca Martin, T M, Foussat, A, Francis, D, Franz, S, Fratianni, S, Froidevaux, D, Gallas, M V, Garonne, V G, Gayde, J C, Gianotti, F, Gildemeister, O, Godlewski, J, Gollub, N P, Gonidec, A, Goossens, L, Gorini, B, Gorski, B T, Goulette, M, Grabowska-Bold, I, Grognuz, J, Grothe, M E M, Gruwe, M, Gschwendtner, E M, Haas, S, Hahn, F, Haider, S, Hallgren, B, Hatch, M, Haug, F, Hauschild, M, Hauviller, C, Hawkings, R J, Henriques Correia, A M, Hervas, L, Hocker, Andreas>, Hoffmann, H F, Hooton, I, Hryn'ova, T, Hulsbergen, W, Iengo, P, Inigo-Golfin, J, Jaekel, M, Jarp, S, Jarron, P, Jenni, P, Jones, R, Jonsson, O, Joos, M, Joram, C, Kaplon, J, Kataoka, M, Klioutchnikova, T, Knezo, E, Knobloch, J, Koffas, T, Kono, T, Krasznahorkay, A, Kruger, K, Kubischta, W, Lasseur, C, Le Bihan, A C, Leahu, L, Leahu, M, Lee, H, Lehmann Miotto, G, Letheren, M, Lichard, P, Liko, D, Lucas, S, Lytken, E, Mair, K, Mandl, M, Mapelli, A, Mapelli, L, Marchesotti, M, Martin, B, Maugain, J M, McLaren, R A, Meinhard, H, Meirosu, C, Menot, C, Meyer, T C, Michelotto, M, Miele, P, Mladenov, D, Molina-Perez, J, Mornacchi, G, Nairz, A M, Nassiakou, M, Nessi, M, Nicquevert, B, Niinikoski, T, Nordberg, M, Nunes, R, Nyman, T, Onea, A, Pailler, P M, Palestini, S, Palla, J, Papadopoulos, I, Parkman, C, Passardi, G, Passmore, M S, Pauly, T, Pengo, R, Perez Reale, V, Pernegger, H, Petersen, J, Petersen, T C, Pezzetti, M, Pimenta Dos Santos, M A, Pirotte, O, Placci, A, Pommes, K, Poppleton, A, Pospichal, P, Poulard, G, Price, M J, Primor, D, Rabbers, J J, Rammer, H, Rangod, S, Raymond, M, Rembser, C, Roe, S, Rohrbach, F, Ruggiero, G, Sbrissa, E, Schaller, M, Schlager, G, Schlenker, S, Schmid, P, Schmitt, C, Schoerner, T, Schuh, S, Schuler, G, Schweiger, D, Schwick, C, Siebel, M, Sloper, J, Speckmayer, P, Spegel, M, Spigo, G, Spiwoks, R, Sprachmann, G, Stavrianakou, M, Stelzer, H J, Szeless, B, Taboada Gameiro, S, Tappern, G P, Ten Kate, H, Tique Aires Viegas, F J, Treichel, M, Tremblet, L, Tyrvainen, H, Unal, G, Van der Bij, H, Vandelli, W, Vandoni, G, Varela Rodriguez, F, Veness, R, Verducci, M, Vincke, H, von Boehn-Buchholz, R, Voss, R, Vuillemin, V, Vuillermet, R, Wallny, R S, Weilhammer, P M, Wells, P S, Wenig, S, Werner, P, Wiesmann, M, Wildauer, A, Wilkens, H G, Witzeling, W, Wotschack, J, Zajacova, Z, Zema, P F, Zsenei, A, Anderson, K J, Brubaker, E, Costin, T, Feng, E J, Gardner, R W, Gupta, A, Hurwitz, M, Jen-La Plante, I, Kapliy, A, Mambelli, M, Merritt, F S, Oreglia, M J, Pilcher, J E, Shochet, M J, Smirnov, Y, Usai, G, Yorita, K, Apsimon, R, Baines, J T, Barclay, P, Barnett, B M, Batchelor, L E, Baynham, D E, Bizzell, J P, Botterill, D, Brawn, I P, Butterworth, J, Carr, F S, Clifft, R W, Cragg, D A, Dallison, S J, Densham, C J, Emeliyanov, D, Fisher, S M, Gallop, B J, Gee, C N P, Gibson, M D, Gillman, A R, Greenfield, D, Hart, J C, Hatley, R W, Hayler, T, Haywood, S J, Hicheur, A, Holt, R, Holtom, E, Jones, A, Kirk, J, Li, W, Lintern, A J, Macwaters, C, Matheson, J, McCubbin, N A, McMahon, S J, Middleton, R, Morrissey, M C, Murray, W J, Nelson, C, Nichols, A, Norton, P R, Perera, V J O, Phillips, P W, Prieur, D, Qian, W, Rochford, J H, Sankey, D P C, Scott, W G, Shah, T P, Smith, B, Sole, D, Tarrant, J, Towndrow, E F, Tricoli, A, Tyndel, M, Villani, E G, Warner, G P, Weber, M, Wickens, F J, Wielers, M, Wilmut, I, Busato, E, Calvet, D, Cogneras, E, Defay, P O, Febbraro, R, Garde, V, Gris, P L Y, Guicheney, C J, Montarou, G, Pallin, D, Podlyski, F, Santoni, C, Says, L P, Vazeille, F, Bertelsen, H, Czyczula, Z, Dam, M, Driouichi, C, Facius, K, Hansen, F H, Hansen, J R, Hansen, J B, Hansen, J D, Hansen, P H, Klinkby, E B, Lindahl, A, Lundquist, J, Mackeprang, R, Nilsson, B S, Rensch, B, Waananen, A, Xella-Hansen, S, Adorisio, C, Castrovillari, F, Crosetti, G, La Rotonda, L, Lamanna, E, Meoni, E, Policicchio, A, Salvatore, D, Schioppa, M, Susinno, G, Klaiber-Lodewigs, J, Klingenberg, R, Krasel, O, Kudlaty, J, Mass, M, Rajek, S, Reisinger, I, Walbersloh, J, Weber, J, Weingarten, J, Wunstorf, R, Kobel, M, Lacker, H, Ludwig, A, Mader, W F, Schaarschmidt, J, Schumacher, J, Schwierz, R, Warsinsky, M, Aleksandrov, I N, Barashkou, A, Bardin, D Y, Batusov, V, Bednyakov, V A, Boyko, I R, Budagov, I A, Chelkov, G A, Chepurnov, V F, Dedovich, D V, Demichev, M, Evtoukhovitch, P, Glonti, G L, Gongadze, A, Gostkin, M I, Gousakov, I, Grigalashvili, N, Ilyushenka, Y, Kakurin, S, Kalinovskaya, L V, Kazarinov, M Y, Kekelidze, G D, Kharchenko, D, Khovanskiy, N, Khramov, E, Kolesnikov, V, Kotov, V M, Kruchonak, U, Krumshteyn, Z V, Kukhtin, V, Ladygin, E, Lazarev, A B, Liabline, M, Lysan, V, Malyukov, S, Manjavidze, I D, Mialkovski, V, Minashvili, I A, Mineev, M, Nanava, G, Neganov, A, Nikolaev, K, Olchevski, A G, Perepelkin, E, Peshekhonov, V D, Romanov, V M, Rumyantsev, L, Rusakovich, N A, Sadykov, R, Shilov, S, Shiyakova, M, Sisakyan, A N, Topilin, N D, Usov, Y, Vinogradov, V B, Vorozhtsov, A S, Vorozhtsov, S B, Zhemchugov, A, Zhuravlov, V, Zimin, N I, Benjamin, P, Bocci, A, Ebenstein, W L, Fowler, A J, Ko, B R, Oh, S H, Thomas, A, Wang, C, Ahmed, H, Buchanan, N J, Caron, B, Chen, L, Gingrich, D M, Liu, S, Lu, J, Macpherson, A, MacQueen, D, Moore, R W, Pinfold, J L, Soluk, R, Soukup, J, Yao, Y, Berry, T, Boorman, G, Cheng, T L, Cooper-Smith, N J, Cowan, G, De Santo, A, George, S, Goncalo, R, Green, B, Hollyman, G, Kilvington, G, Lowe, A, McGarvie, S, McMahon, T R, Misiejuk, A, Potter, C J, Strong, J A, Tamsett, M C, Teixeira-Dias, P, Adamyan, F, Grabski, V, Hakobyan, H, Mkrtchyan, S, Simonyan, M, Antonelli, M, Barone, M, Beretta, M, Bertolucci, S, Bilokon, H, Braccini, S, Cerutti, F, Chiarella, V, Curatolo, M, Esposito, B, Ferrer, M L, Gatti, C, Laurelli, P, Maccarrone, G, Martini, A, Miscetti, S, Nicoletti, G, Sansoni, A, Ventura, S, Vilucchi, E, Wen, M, Ahles, F, Bianchi, R M, Buszello, K P, Caron, S, Carpentieri, C, Christov, A, Dahlhoff, A, Dietrich, J, Eckert, S, Feld, L, Fox, H, Heldmann, M, Herten, G, Jakobs, K, Joos, D, Ketterer, C, Kollefrath, M, Kononov, A I, Kramer, A, Lai, S, Landgraf, U, Ludwig, I, Ludwig, J, Lumb, D, Maassen, M, Mahboubi, K, Meinhardt, J, Meisel, F, Messmer, I, Mohr, W, Nilsen, H, Parzefall, U, Pfeifer, B, Piacquadio, G, Portell Bueso, X, Raufer, T, Runge, K, Schroff, D, Titov, M, Tobias, J, Webel, M, Weiser, C, Xie, S, Zimmermann, S, Abdelalim, A A, Barbier, G, Blondel, A, Bonino, R, Chamizo llatas, M, Clark, A, Couyoumtzelis, C, D'Onofrio, M, Demierre, P, Diaz Gomez, M M, Efthymiopoulos, I, Eifert, T, Ferrere, D, Gadomski, S, Gaumer, O, Hamilton, A, Kambara, H, Keil, M, La Marra, D, Lefevre, R P, Leger, A, Liu, Y, Macina, D, Mangin-Brinet, M, Mazzucato, F, Mikulec, B, Moneta, L, Morone, M C, Orellana, F, Perrin, E, Pohl, M, Robichaud-Veronneau, A, Rosselet, L, Sfyrla, A, Straessner, A, Vu Anh, T, Vuaridel, B, Wu, X, Barberis, D, Beccherle, R B, Caso, C, Cervetto, M, Coccaro, A, Cuneo, S, Dameri, M, Darbo, G, Ferro, F, Gagliardi, G, Garelli, N, Gemme, C, Kostyukhin, V V, Morettini, P, Odino, G A, Olcese, M, Osculati, B, Parodi, F, Rossi, L P, Schiavi, C, Stenzel, H, Allwood-Spiers, S E, Bates, R L, Bell, W H, Buttar, C M, Cheplakov, A, Clements, D, Collins-Tooth, C, D'Auria, S, Doherty, T, Doyle, A T, Ferrag, S, Kenyon, M, McGlone, H, Nicholson, C, O'Shea, V, Pickford, A, Raine, C, Robson, A, Saxon, D H, Shaw, C, Smith, K M, St Denis, R D, Stewart, G, Thompson, A S, Wright, C, Ay, C, Quadt, A, Uhrmacher, M, Albrand, S, Andrieux, M L, Belhorma, B, Beteille, A, Boyer, B H, Carcagno, Y, Chevallier, F, Clement, B C, Collot, J, de Saintignon, P, Dzahini, D, Ferrari, A, Fulachier, J, Hostachy, J Y, Labbe, J A, Lambert, F, Ledroit-Guillon, F, Lleres, A, Lucotte, A, Malek, F, Martin, Ph>, Morel, J, Petit, P J F, Crepe-Renaudin, S R C, Rey-Campagnolle, M, Saboumazrag, S, Trocme, B, Viret, S, Behar Harpaz, S, Ben Ami, S, Bressler, S, Gernizky, Y, Hadash, E, Harel, A, Kajomovitz, E, Landsman, H, Lifshitz, R, Lupu, N, Panikashvili, N, Rozen, Y, Tarem, S, Barisonzi, M, Ehrenfeld, W, Glazov, A, Haller, J, Kama, S, Kowalski, H, Mamuzic, J, Medinnis, M, Moll, A, Naumann, T, Placakyte, R, Terwort, M, Vogt, H, Addy, T N, Harvey, A, Long, M C, McFarlane, K W, Shin, T, Vassilakopoulos, V I, Barreiro Guimaraes da Costa, J, Black, K M, Brandenburg, G W, Feldman, G, Haggerty, R, Harder, S, Hurst, P, Huth, J, Kashif, L, Outschoorn, V Martinez>, Moed, S, Morii, M, Oliver, J, Prasad, S, Riegler, W, Sansone, S, Smith, B C, Achenbach, R, Andrei, V, Geweniger, C, Hanke, P, Kluge, E E, Lendermann, V, Meier, K, Schmitt, K, Schultz-Coulon, H C, Stamen, R, Weber, P, Nagasaka, Y, Benekos, N, Errede, D, 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Botchev, B, Engelmann, R, Finocchiaro, G, Goodson, J J, Grimm, K, Khodinov, A, McCarthy, R L, Rijssenbeek, M, Steffens, J L, Thioye, M, Yurkewicz, A, Grahn, K J, Hansson, P, Lund-Jensen, B, Tayalati, Y, Bergeaas, E, Berglund, S, Bohm, C, Clement, C, Eriksson, D, Gellerstedt, K, Hellman, S, Hidvegi, A, Holmgren, S O, Johansen, M, Johansson, K E, Jon-And, K, Lesser, J, Milstead, D A, Moa, T, Ramstedt, M, Sellden, B, Silverstein, S B, Lee, J S H, Peak, L S, Saavedra, A F, Varvell, K E, Waugh, A T, Chu, M L, Hou, S, Lee, S C, Lin, S C, Qing, D, Ren, Z, Teng, P K, Zhou, S, Zhou, Y, Chikovani, L, Djobava, T, Khubua, J, Mosidze, M, Tskhadadze, E G, Abramowicz, H, Alexander, G, Amram, N, Bella, G, Ben Moshe, M, Benary, O, Benhammou, Y, Brodet, E, Etzion, E, Ginzburg, J, Mahalalel, Y, Oren, Y, Reinherz-Aronis, E, Soffer, A, Urkovsky, E, De, K, Dipanjan, R, Farbin, A, Kim, H, Li, J, Nilsson, P, Ozturk, N, Pravahan, R, Sosebee, M, Spurlock, B, Vartapetian, A, White, A, Yu, J, Anastopoulos, C, Bachas, K, Bouzakis, K, Christidi, I A, Krepouri, A, Liolios, A, Petridou, C, Sampsonidis, D, Tsiafis, I, Bratzler, U, Fukunaga, C, Asai, S, Imori, M, Ishino, M, Kanaya, N, Kaneda, M, Kataoka, Y, Kawamoto, T, Kobayashi, T, Kubota, T, Mashimo, T, Matsumoto, H, Matsunaga, H, Nomoto, H, Okawa, H, Sakamoto, H, Tanaka, J, Ueda, I, Yamamoto, S, Bailey, D C, Gibson, A, Gorbounov, P A, Groer, L S, Guo, B, Joo, K K, Knecht, N K, Krieger, P, Le Maner, C, Ma, L L, Martens, F K, Mayer, J K, Mazini, R, Orr, R S, Rosenbaum, G A, Savard, P, Sinervo, P, Teuscher, R J, Trischuk, W, Amako, K, Arai, Y, Doi, Y, Haruyama, T, Ikegami, Y, Ikeno, M, Ishii, K, Iwasaki, H, Jinnouchi, O, Kagawa, S, Kanzaki, J, Kawai, M, Kohriki, T, Kondo, T, Kondo, Y, Makida, Y, Manabe, A, Murakami, K, Nagano, K, Nozaki, M, Odaka, S, Ozone, K, Sasaki, O, Sasaki, T, Tanaka, K, Terada, S, Tojo, J, Tokushuku, K, Tsuno, S, Unno, Y, Yamamoto, A, Yamaoka, H, Yasu, Y, Hara, K, Inoue, K, Kim, S H, Maruyama, T, Mochizuki, A, Nagai, Y, Nakamura, K, Nakamura, Y, Ukegawa, F, Mann, W A, Napier, A, Rolli, S, Sliwa, K, Todorova-Nova, S, Acharya, B S, Cauz, D, Cobal, M, De Lotto, B, Del Papa, C, Giordani, M P, Grassmann, H, Luisa, L, Santi, L, Belanger-Champagne, C, Bingefors, N, Brenner, R, Coniavitis, E, Ekelof, T, Ellert, M, Flechl, M, Hansen, C J, Lindquist, L, Ruber, R, Abdallah, J, Ballester, F, Bernabeu, J, Cabrera Urban, S, Cabruja Casas, E, Calderon Terol, D, Camarena, F, Campabadal Segura, F, Castelo, J, Castillo Gimenez, V, Civera, J V, Costa, M J, Almenar, C Cuenca>, Diez Cornell, S, Escobar, C, Fassi, F, Ferrer, A, Fleta Corral, C M, Fuster, J, Garcia, C, Garcia Navarro, J E, Gil Botella, Ines>, Gonzalez de la Hoz, S, Gonzalez Millan, V, Gonzalez-Sevilla, S, Higon-Rodriguez, E, Kaci, M, Lacasta, C, Lacuesta, V R, Lara, V, Llosa Llacer, G, Lozano Fantoba, M, Lopez-Amengual, J M, March, L, Marti i Garcia, S, Martinez Lacambra, C, Minano, M, Mitsou, V A, Modesto, P, Moles Valls, R M, Moreno, A, Pellegrini, G, Poveda, J, Rafi, J M, Roldan, J, Romance, J B, Ros, E, Ruiz-Martinez, A, Salt, J, Salvachua Ferrando, B M, Sanchis Lozano, M A, Sanchis Peris, E, Santander, J, Solans, C A, Medel, J Soret>, Suay, L Sospedra>, Sanchez, J, Torres Pais, J G, Ullan Comes, M, Valero, A, Valls Ferrer, J A, Vives, R, Vos, M, Axen, A, Gay, C, Loh, C W, Hodges, T A, Ishizawa, Y, Kurchaninov, L L, Langstaf, R R, Losty, M J, Moraes, A, Oram, C J, Tafirout, R, Trigger, I M, Walker, R, Wellisch, H P, Albert, J, Astbury, A, Berghaus, F, Courneyea, L, Fincke-Keeler, M, Honma, A, Ince, T, Keeler, R, Kowalewski, Robert V, Lefebvre, M, Lelas, D, Lessard, J R, McPherson, R A, Poffenberger, P, Seuster, R, Sobie, R, Taylor, R P, Voss, K C, Daly, C H, Forbush, D A, Gaudio, G, Kuykendall, W, Lubatti, H J, Mockett, P, Rothberg, J, Twomey, M S, Wang, J C, Watts, G, Zhao, T, Griesmayer, E, Chen, X, Dos Anjos, A, Fang, Y, Fasching, D, Ferguson, D, Flores Castillo, L R, Goldschmidt, N, Gonzalez, S, Jared, R C, Joseph, J, Leung 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Soderberg, M, Kopke, L, Schafer, U, Muller, M, Gottfert, T, Hartel, R, Mohrdieck-Mock, S, Schmucker, H, Strohmer, R, Konig, A C, Rohne, O, Asman, B, Engstrom, M, Sjolin, J, Imhauser, M, Mattig, P, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire 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L., FIRAN A., FISCHER P., FISHER MJ., FISHER SM., FLAMINIO V., FLAMMER J., FLECHL M., FLECK I., FLEGEL W., FLEISCHMANN P., FLEISCHMANN S., CORRAL CMF., FLEURET F., FLICK T., FLIX J., CASTILLO LRF., FLOWERDEW MJ., FOHLISCH F., FOKITIS M., MARTIN TMF., FOPMA J., FORBUSH DA., FORMICA A., FOSTER JM., FOURNIER D., FOUSSAT A., FOWLER AJ., FOX H., FRANCAVILLA P., FRANCIS D., FRANZ S., FRASER JT., FRATERNALI M., FRATIANNI S., FREESTONE J., FRENCH RS., FRITSCH K., FROIDEVAUX D., FROST JA., FUKUNAGA C., FULACHIER J., TORREGROSA EF., FUSTER J., GABALDON C., GADOMSKI S., GAGLIARDI G., GAGNON P., GALLAS EJ., GALLAS MV., GALLOP BJ., GAN KK., GANNAWAY FC., GAO YS., GAPIENKO VA., GAPONENKO A., GARCIA C., GARCIA-SCIVERES M., NAVARRO JEG., GARDE V., GARDNER RW., GARELLI N., GARITAONANDIA H., GARONNE VG., GARVEY J., GATTI C., GAUDIO G., GAUMER O., GAUTARD V., GAUZZI P., GAVRILENKO IL., GAY C., GAYDE JC., GAZIS EN., GAZO E., GEE CNP., GEICH-GIMBEL C., GELLERSTEDT K., GEMME C., GENEST MH., GENTILE S., 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NANAVA G., NAPIER A., NASSIAKOU M., NASTEVA I., NATION NR., NAUMANN T., NAUYOCK F., NDERITU SK., NEAL HA., NEBOT E., NECHAEVA P., NEGANOV A., NEGRI A., NEGRONI S., NELSON C., NEMECEK S., NEMETHY P., NEPOMUCENO AA., NESSI M., NESTEROV SY., NEUKERMANS L., NEVSKI P., NEWCOMER FM., NICHOLS A., NICHOLSON C., NICHOLSON R., NICKERSON RB., NICOLAIDOU R., NICOLETTI G., NICQUEVERT B., NICULESCU M., NIELSEN J., NIINIKOSKI T., NIINIMAKI MJ., NIKITIN N., NIKOLAEV K., NIKOLIC-AUDIT I., NIKOLOPOULOS K., NILSEN H., NILSSON BS., NILSSON P., NISATI A., NISIUS R., NODULMAN LJ., NOMACHI M., NOMOTO H., NOPPE JM., NORDBERG M., FRANCISCO ON., NORTON PR., NOVAKOVA J., NOWAK M., NOZAKI M., NUNES R., HANNINGER GN., NUNNEMANN T., NYMAN T., O'CONNOR P., O'NEALE SW., O'NEIL DC., O'NEILL M., O'SHEA V., OAKHAM FG., OBERLACK H., OBERMAIER M., OBERSON P., OCHI A., OCKENFELS W., ODAKA S., ODENTHAL I., ODINO GA., OGREN H., OH SH., OHSHIMA T., OHSHITA H., OKAWA H., OICESE M., OLCHEVSKI AG., OLIVER C., OLIVER J., GOMEZ MO., OLSZEWSKI A., OLSZOWSKA J., OMACHI C., ONEA A., ONOFRE A., ORAM CJ., ORDONEZ G., OREGLIA MJ., ORELLANA F., OREN Y., ORESTANO D., ORLOV IO., ORR RS., ORSINI F., OSBORNE LS., OSCULATI B., OSUNA C., OTEC R., OTHEGRAVEN R., OTTEWELL B., OULD-SAADA F., OURAOU A., OUYANG Q., OYE OK., OZCAN VE., OZONE K., OZTURK N., PAGES AP., PADHI S., ARANDA CP., PAGANIS E., PAIGE F., PAILLER PM., PAJCHEL K., PALESTINI S., PALLA J., PALLIN D., PALMER MJ., PAN YB., PANIKASHVILI N., PANIN VN., PANITKIN S., PANTEA D., PANUSKOVA M., PAOLONE V., PAOLONI A., PAPADOPOULOS I., PAPADOPOULOU T., PARK I., PARK W., PARKER MA., PARKER S., PARKMAN C., PARODI F., PARSONS JA., PARZEFALL U., PASQUALUCCI E., PASSARDI G., PASSERI A., PASSMORE MS., PASTORE F., PATARAIA S., PATE D., PATER JR., PATRICELLI S., PAULY T., PAUNA E., PEAK LS., PEETERS SJM., PEEZ M., PEI E., PELEGANCHUK SV., PELLEGRINI G., PENGO R., PEQUENAO J., PERANTONI M., PERAZZO A., PEREIRA A., PEREPELKIN E., PERERA VJO., CODINA EP., REALE VP., PERIC I., PERINI L., PERNEGGER H., PERRIN E., PERRINO R., PERRODO P., PERROT G., PERUS P., PESHEKHONOV VD., PETEREIT E., PETERSEN J., PETERSEN TC., PETIT PJF., PETRIDOU C., PETROLO E., PETRUCCI F., PETTI R., PEZZETTI M., PFEIFER B., PHAN A., PHILLIPS AW., PHILLIPS PW., PIACQUADIO G., PICCININI M., PICKFORD A., PIEGAIA R., PIER S., PILCHER JE., PILKINGTON AD., DOS SANTOS MAP., PINA J., PINFOLD JL., PING J., PINHAO J., PINTO B., PIROTTE O., PLACAKYTE R., PLACCI A., PLAMONDON M., PLANO WG., PLEIER MA., PLESKACH AV., PODKLADKIN S., PODLYSKI F., POFFENBERGER P., POGGIOLI L., POHL M., POLAK I., POLESELLO G., POLICICCHIO A., POLINI A., POLYCHRONAKOS V., POMAREDE DM., POMMES K., PONSOT P., PONTECORVO L., POPE BG., POPESCU R., POPOVIC DS., POPPLETON A., POPULE J., BUESO XP., POSCH C., POSPELOV GE., POSPICHAL P., POSPISIL S., POSTRANECKY M., POTRAP IN., POTTER CJ., POULARD G., POUSADA A., POVEDA J., PRABHU R., PRALAVORIO P., PRASAD S., PRAST J., PRAT S., PRATA M., PRAVAHAN R., PREDA T., PRETZ K., PRIBY L., PRICE D., PRICES LE., PRICE MJ., PRICHARD PM., PRIEUR D., PRIMAVERA M., PRIMOR D., PROKOFIEV K., PROSSO E., PROUDFOOT J., PRZYSIEZNIAK H., PUIGDENGOLES C., PURDHAM J., PUROHIT M., PUZO P., PYLAEV AN., PYLYPCHENKO Y., QI M., QIAN J., QIAN W., QIAN Z., QING D., QUADT A., QUARRIE DR., QUAYLE WB., RABBERS JJ., RADEKA V., RAFI JM., RAGUSA F., RAHIMI AM., RAHM D., RAINE C., RAITH B., RAJAGOPALAN S., RAJEK S., RAMMER H., RAMSTEDT M., RANGOD S., RATOFF PN., RAUFER T., RAUSCHER F., RAUTER E., RAYMOND M., READS AL., REBUZZI D., REDLINGER GR., REEVES K., REHAK M., REICHOLD A., REINHERZ-ARONIS E., REISINGER I., RELJIC D., REMBSER C., REN Z., RENAUDIN-CREPE SRC., RENKEL P., RENSCH B., RESCIA S., RESCIGNO M., RESCONI S., RESENDE B., REWIERSMA P., REY J., REY-CAMPAGNOLLE M., REZAIE E., REZNICEK P., RICHARDS RA., RICHER JP., RICHTER RH., RICHTER R., RICHTER-WAS E., RIDEL M., RIEGLER W., RIEKE S., RIJPSTRA M., RIJSSENBEEK M., RIMOLDI A., RIOS RR., DACHS IR., RIVLINE M., RIVOLTELLA G., RIZATDINOVA F., ROBERTSON SH., ROBICHAUD-VERONNEAU A., ROBINS S., ROBINSON D., ROBSON A., ROCHFORD JH., RODA C., RODIER S., ROE S., ROHNE O., ROHRBACH F., ROLDAN J., ROLLI S., ROMANCE JB., ROMANIOUK A., ROMANOV VM., ROMEO G., ROOS L., ROS E., ROSATI S., ROSENBAUM F., ROSENBAUM GA., ROSENBERG EI., ROSSELET L., ROSSI LP., ROSSI L., ROTARU M., ROTHBERG J., ROTTLANDER I., ROUSSEAU D., ROZANOV A., ROZEN Y., RUBER R., RUCKERT B., RUDOLPH G., RUHR F., RUGGIERI F., RUGGIERO G., RUIZ H., RUIZ-MARTINEZ A., RULIKOWSKA-ZAREBSKA E., RUMIANTSEV V., RUMYANTSEV L., RUNGE K., RUNOLFSSON O., RUSAKOVICH NA., RUST DR., RUTHERFOORD JP., RUWIEDEL C., RYABOV YF., RYADOVIKOV V., RYAN P., RYBKINE G., DA COSTA JS., SAAVEDRA AF., SABOUMAZRAG S., SADROZINSKI HFW., SADYKOV R., SAKAMOTO H., SALA P., SALAMON A., SALEEM M., SALIHAGIC D., SALT J., BAUZA OS., FERRANDO BMS., SALVATORE D., SALZBURGER A., SAMPSONIDIS D., SAMSET BH., SANCHEZ CAS., LOZANO MAS., PERIS ES., SANDAKER H., SANDER HG., SANDHOFF M., SANDVOSS S., SANKEY DPC., SANNY B., SANSONE S., SANSONI A., RIOS CS., SANTANDER J., SANTI L., SANTONI C., SANTONICO R., SANTOS J., SAPINSKI M., SARAIVA JG., SARRI F., SASAKI O., SASAKI T., SASAO N., SATSOUNKEVITCH I., SAUVAGE D., SAUVAGE G., SAVARD P., SAVINE AY., SAVINOV V., SAVOY-NAVARRO A., SAVVA P., SAXON DH., SAYS LP., SBARRA C., SBRISSA E., SBRIZZI A., SCANNICCHIO DA., SCHAARSCHMIDT J., SCHACHT P., SCHAFER U., SCHAFFER AC., SCHAILE D., SCHALLER M., SCHAMOV AG., SCHEGELSKY VA., SCHEIRICH D., SCHERNAU M., SCHERZER MI., SCHIAVI C., SCHICK H., SCHIECK J., SCHIEFERDECKER P., SCHIOPPA M., SCHLAGER G., SCHLENKER S., SCHLERETH JL., SCHMID P., SCHMIDT MP., SCHMITT C., SCHMITT K., SCHMITZ M., SCHMUCKER H., SCHOERNER T., SCHOLTE RC., SCHOTT M., SCHOUTEN D., SCHRAM M., SCHRICKER A., SCHROFF D., SCHUH S., SCHUIJLENBURG HW., SCHULER G., SCHULTES J., SCHULTZ-COULON HC., SCHUMACHER J., SCHUMACHER M., SCHUNE P., SCHWARTZMAN A., SCHWEIGER D., SCHWEMLING P., SCHWICK C., SCHWIENHORST R., SCHWIERZ R., SCHWINDLING J., SCOTT WG., SECKER H., SEDYKH E., SEGUIN-MOREAU N., SEGURA E., SEIDEL SC., SEIDEN A., SEIXAS JM., SEKHNIAIDZE G., SELIVERSTOV DM., SELLDEN B., SEMAN M., SEMPRINI-CESARI N., SERFON C., SERIN L., SEUSTER R., SEVERINI H., SEVIOR ME., SEXTON KA., SFYRLA A., SHAH TP., SHAN L., SHANK JT., SHAPIRO M., SHATALOV PB., SHAVER L., SHAW C., SHEARS TG., SHERWOOD P., SHIBATA A., SHIELD P., SHILOV S., SHIMOJIMA M., SHIN T., SHIYAKOVA M., SHMELEVA A., SHOA M., SHOCHET MJ., SHUPE MA., SICHO P., SIDOTI A., SIEBEL A., SIEBE M., SIEGRIST J., SIJACKI D., SILVA J., SILVERSTEIN SB., SIMAK V., SIMIC L., SIMION S., SIMMONS B., SIMONYAN M., SINERVO P., SIPICA V., SIRAGUSA G., SISAKYAN AN., SIVOKLOKOV S., SJOLIN J., SKUBIC P., SKVORODNEV N., SLATTERY P., SLAVICEK T., SLIWA K., SLOAN TJ., SLOPER J., SMAKHTIN V., SMALL A., SMIRNOV SY., SMIRNOV Y., SMIRNOVA L., SMIRNOVA O., SMITH NA., SMITH BC., SMITH DS., SMITH J., SMITH KM., SMITH B., SMIZANSKA M., SMOLEK K., SNESAREV AA., SNOW SW., SNOW J., SNUVERINK J., SNYDER S., SOARES M., SOARES S., SOBIE R., SODOMKA J., SODERBERG M., SOFFER A., SOLANS CA., SOLAR M., SOLE D., CAMILLOCCI ES., SOLODKOV AA., SOLOV'YANOV OV., SOLOVIEV I., SOLUK R., SONDERICKER J., SOPKO V., SOPKO B., SORBI M., MEDEL JS., SOSEBEE M., SOSNOVTSEV VV., SUAY LS., SOUKHAREV A., SOUKUP J., SPAGNOLO S., SPANO F., SPECKMAYER P., SPEGEL M., SPENCER E., SPIGHI R., SPIGO G., SPILA F., SPIRITI E., SPIWOKS R., SPOGLI L., SPOUSTA M., SPRACHMANN G., SPURLOCK B., DENIS RDS., STAHL T., STALEY RJ., STAMEN R., STANCU SN., STANECKA E., STANEK RW., STANESCU C., STAPNES S., STARCHENKO EA., STAROBA P., STASTNY J., STAUDE A., STAVINA P., STAVRIANAKOU M., STAVROPOULOS G., STEFANIDIS E., STEFFENS JL., STEKL I., STELZER HJ., STENZEL H., STEWART G., STEWART TD., STILLER W., STOCKMANNS T., STODULSKI M., STONJEK S., STRADLING A., STRAESSNER A., STRANDBERG J., STRANDLIE A., STRAUSS M., STRICKLAND V., STRIEGEL D., STRIZENEC P., STROHMER R., STROM DM., STRONG JA., STROYNOWSKI R., STUGU B., STUMER I., SU D., SUBRAMANIA S., SUCHKOV SI., SUGAYA Y., SUGIMOTO T., SUK M., SULIN VV., SULTANOV S., SUN Z., SUNDAL B., SUSHKOV S., SUSINNO G., SUTCLIFFE P., SUTTON MR., SVIRIDOV YM., SYKORA I., SZCZYGIEL RR., SZELESS B., SZYMOCHA T., SANCHEZ J., TA D., GAMEIRO ST., TADEL M., TAFIROUT R., TAGA A., TAKAI H., TAKASHIMA R., TAKEDA H., TAKESHITA T., TALBY M., TALYSHEV A., TAMSETT MC., TANAKA J., TANAKA K., TANAKA R., TANAKA S., TANAKA Y., TAPPERN GP., TAPPROGGE S., TAREM S., TARRADE F., TARRANT J., TARTARELLI G., TAS P., TASEVSKY M., TAYALATI Y., TAYLOR FE., TAYLOR G., TAYLOR GN., TAYLOR RP., TCHERNIATINE V., TEGENFELDT F., TEIXEIRA-DIAS P., TEN KATE H., TENG PK., TER-ANTONYAN R., TERADA S., TERRON J., TERWORT M., TEUSCHER RJ., TEVLIN CM., THADOME J., THION J., THIOYE M., THOMAS A., THOMAS JP., THOMAS TL., THOMAS E., THOMPSON RJ., THOMPSON AS., THUN RP., TIC T., TIKHOMIROV VO., TIKHONOV YA., TIMM S., TIMMERMANS CJWP., TIPTON P., VIEGAS FJTA., TISSERANT S., TITOV M., TOBIAS J., TOCUT VM., TOCZEK B., TODOROVA-NOVA S., TOJO J., TOKAR S., TOKUSHUKU K., TOMASEK L., TOMASEK M., TOMASZ F., TOMOTO M., TOMPKINS D., TOMPKINS L., TOMS K., TONAZZO A., TONG G., TONOYAN A., TOPFEL C., TOPILIN ND., TORRENCE E., PAIS JGT., TOTH J., TOUCHARD F., TOVEY DR., TOVEY SN., TOWNDROW EF., TREFZGER T., TREICHEL M., TREIS J., TREMBLET L., TRIBANEK W., TRICOLI A., TRIGGER IM., TRILLING G., TRINCAZ-DUVOID S., TRIPIANA MF., TRISCHUK W., TRKA Z., TROCME B., TRONCON C., TSENG JCL., TSIAFIS I., TSIARESHKA PV., TSIPOLITIS G., TSKHADADZE EG., TSUKERMAN II., TSULAIA V., TSUNO S., TURALA M., CAKIR IT., TURLAY E., TUTS PM., TWOMEY MS., TYNDE M., TYPALDOS D., TYRVAINEN H., TZAMARIOUDAKI E., TZANAKOS G., UEDA I., UHRMACHER M., UKEGAWA F., COMES MU., UNAL G., UNDERWOOD DG., UNDRUS A., UNEL G., UNNO Y., URKOVSKY E., USAI G., USOV Y., VACAVANT L., VACEK V., VACHON B., VAHSEN S., VALDERANIS C., VALENTA J., VALENTE P., VALERO A., VALKAR S., FERRER JAV., VAN DER BIJ H., VAN DER GRAAF H., VAN DER KRAAIJ E., VAN EIJK B., VAN ELDIK N., VAN GEMMEREN P., VAN KESTEREN Z., VAN VULPEN I., VANBERG R., VANDELLI W., VANDONI G., VANIACHINE A., VANNUCCI F., VARANDA M., RODRIGUEZ FV., VARI R., VARNES EW., VAROUCHAS D., VARTAPETIAN A., VARVE KE., VASSILAKOPOULOS VI., VASSILIEVA L., VATAGA E., VAZ L., VAZEILLE F., VEDRINE P., VEGNI G., VEILLET JJ., VELLIDIS C., VELOSO F., VENESS R., VENEZIANO S., VENTURA A., VENTURA S., VERCESI V., VERDUCCI M., VERKERKE W., VERMEULEN JC., VERTOGARDOV L., VETTERLI MC., VICHOU I., VICKEY T., VIEHHAUSER GHA., VIGEOLAS E., VILLA M., VILLANI EG., VILLATE J., VILLELLA I., VILUCCHI E., VINCENT P., VINCKE H., VINCTER MG., VINOGRADOV VB., VIRCHAUX M., VIRET S., VIRZI J., VITALE A., VIVARELLI I., VIVES R., VAQUES FV., VLACHOS S., VOGT H., VOKAC P., VOLLMER CF., VOLPI M., VOLPINI G., VON BOEHN-BUCHHOLZ R., VON DER SCHMITT H., VON TOERNE E., VOROBEL V., VOROBIEV AP., VOROZHTSOV AS., VOROZHTSOV SB., VOS M., VOSS KC., VOSS R., VOSSEBELD JH., VOVENKO AS., VRANJES N., VRBA V., VREESWIJK M., ANH TV., VUARIDEL B., VUDRAGOVIC M., VUILLEMIN V., VUILLERMET R., WANANEN A., WAHLEN H., WALBERSLOH J., WALKER R., WALKOWIAK W., WALL R., WALLNY RS., WALSH S., WANG C., WANG JC., WAPPLER F., WARBURTON A., WARD CP., WARNER GP., WARREN M., WARSINSKY M., WASTIE R., WATKINS PM., WATSON AT., WATTS G., WAUGH AT., WAUGH BM., WEAVERDYCK C., WEBEL M., WEBER G., WEBER J., WEBER M., WEBER P., WEIDBERG AR., WEILHAMMER PM., WEINGARTEN J., WEISER C., WELLENSTEIN H., WELLISCH HP., WELLS P., WEMANS A., WEN M., WENAUS T., WENDLER S., WENGLER T., WENIG S., WERMES N., WERNEKE P., WERNER P., WERTHENBACH U., WHEELER-ELLIS SJ., WHITAKER SP., WHITE A., WHITE MJ., WHITE S., WHITTINGTON D., WICEK F., WICKE D., WICKENS FJ., WIEDENMANN W., WIELERS M., WIENEMANN P., WIESMANN M., WIJNEN T., WILDAUER A., WILHELM I., WILKENS HG., WILLIAMS HH., WILLIS W., WILLOCQ S., WILMUT I., WILSON JA., WILSON A., WINGERTER-SEEZ I., WINTON L., WITZELING W., WLODEK T., WOEHRLING E., WOLTER MW., WOLTERS H., WOSIEK B., WOTSCHACK J., WOUDSTRA MJ., WRIGHT C., WU SL., WU X., WUESTENFELD J., WUNSTORF R., XELLA-HANSEN S., XIANG A., XIE S., XIE Y., XU G., XU N., YAMAMOTO A., YAMAMOTO S., YAMAOKA H., YAMAZAKI Y., YAN Z., YANG H., YANG JC., YANG S., YANG UK., YANG Y., YANG Z., YAO WM., YAO Y., YARRADODDI K., YASU Y., YE J., YILMAZ M., YOOSOOFMIYA R., YORITA K., YOSHIDA H., YOSHIDA R., YOUNG C., YOUSSEF SP., YU D., YU J., YU M., YU X., YUAN J., YURKEWICZ A., ZAETS VG., ZAIDAN R., ZAITSEV AM., ZAJAC J., ZAJACOVA Z., ZALITE AY., ZALITE YK., ZANEO L., ZARZHITSKY P., ZAYTSEV A., ZDRAZIL M., ZEITNITZ C., ZELLER M., ZEMA PF., ZENDLER C., ZENIN AV., ZENIS T., ZENONOS Z., ZENZ S., ZERWAS D., ZHANG H., ZHANG J., ZHENG W., ZHANG X., ZHAO L., ZHAO T., ZHAO X., ZHAO Z., ZHELEZKO A., ZHEMCHUGOV A., ZHENG S., ZHICHAO L., ZHOU B., ZHOU N., ZHOU S., ZHOU Y., ZHU CG., ZHU HZ., ZHUANG XA., ZHURAVLOV V., ZILKA B., ZIMIN NI., ZIMMERMANN S., ZIOLKOWSKI M., ZITOUN R., ZIVKOVIC L., ZMOUCHKO VV., ZOBERNIG G., ZOCCOLI A., ZOELLER MM., ZOLNIEROWSKI Y., ZSENEI A., ZUR NEDDEN M., ZYCHACEK V., Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), G., Aad, Aloisio, Alberto, Alviggi, Mariagrazia, Canale, Vincenzo, Cevenini, Francesco, Chiefari, Giovanni, DELLA VOLPE, Domenico, Merola, Leonardo, Patricelli, Sergio, Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Bianco, Michele, G., Cataldi, G., Chiodini, Coluccia, MARIA RITA, Gorini, Edoardo, F., Grancagnolo, Grancagnolo, Sergio, R., Perrino, Primavera, Margherita, Siragusa, Giovanni, Spagnolo, Stefania Antonia, Ventura, Andrea, Doğuş Üniversitesi, Fen Edebiyat Fakültesi, Fizik Bölümü, TR3959, Çetin, Serkant Ali, Abdelalim Aly, Ahmed Aly, Barbier, Gerard, Blondel, Alain, Bonino, Roberto, Chamizo Llatas, Maria, Clark, Allan Geoffrey, Couyoumtzelis, Christian, D'Onofrio, Monica, Demierre, Philippe, Diaz-Gomez, Manuel, Efthymiopoulos, Ilias, Eifert, Till, Ferrere, Didier, Gadomski, Szymon, Gaumer, Olivier, Hakobyan, Hayk, Hamilton, Andrew, Kambara, Hisanori, Keil, Markus, La Marra, Daniel, Lefevre, Régis, Leger, Annie, Liu, Yanwen, Macina-Buono, Daniela, Mangin-Brinet, Mariane, Mazzucato, Federica, Mikulec, Bettina, Moneta, Lorenzo, Morone, Maria Cristina, Orellana, Frédérik, Perrin, Eric, Pohl, Martin, Robichaud-Veronneau, Andrée, Rosselet, Laurent, Sfyrla, Anna, Straessner, Arno, Vu Anh, Tuan, Vuaridel, Bertrand, Wu, Xin, Faculdade de Engenharia, UCL - SST/IRMP - Institut de recherche en mathématique et physique, ATLAS (IHEF, IoP, FNWI), Aad, G, Petrucci, Fabrizio, and Ceradini, Filippo

Subjects
Heavy-ion collisions, Optical alignment systems, Física [Ciências exactas e naturais], ATLAS LHC High Energy Physics, Physics::Instrumentation and Detectors, Ciencias Físicas, 01 natural sciences, High-level trigger, Trigger and data acquisition, Particle identification, Tracking algorithms, Optical fibres, Transition radiation, Drift tubes, CERN, Fluorinert cooling, Jets, Superconducting magnets, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Bunch-crossings, Detectors and Experimental Techniques, Nuclear Experiment, Instrumentation, Mathematical Physics, ATLAS Experiment, Impact parameter measurements, Muons, Resistive-plate chambers, Solenoidal field, Toroidal field, Settore FIS/01 - Fisica Sperimentale, ATLAS, Accordion geometry, Missing transverse energy, Detector control system, Carbon-fibre reinforced plastics, Trigger chambers, LHC, Minimum-bias events, CIENCIAS NATURALES Y EXACTAS, Sampling calorimeters, Precision-tracking chambers, Event filter, Pixel detectors, Accelerator, Longitudinal segmentation, Electrons, ddc:500.2, Calorimetry, Taus, Lateral segmentation, b-tagging, Proton-proton collisions, Physical sciences [Natural sciences], Silicon micro-strip detectors, Bandwidth, Inner detector, Muon spectrometer, Forward detectors, 0103 physical sciences, Cerenkov light, Pile-up, Magnetic field measurements, Hall probes, Charged-particle tracking, Vertex measurement, Time-over-threshold, Radiation-hard electronics, Liquid argon, Scintillator tiles, Electromagnetic and hadronic interactions, Forward calorimetry, Thin-gap chambers, Roman Pots, Zero-degree calorimetry, Processor farm, Leptons, Photons, Vertexing algorithms, 010306 general physics, accelerator, accordion geometry, atlas, bandwidth, bunch-crossings, calorimetry, carbon-fibre reinforced plastics, cerenkov light, cern, charged-particle tracking, detector control system, drift tubes, electromagnetic and hadronic interactions, electrons, event filter, fluorinert cooling, forward calorimetry, forward detectors, hall probes, heavy-ion collisions, high-level trigger, impact parameter measurements, inner detector, jets, lateral segmentation, leptons, lhc, liquid argon, longitudinal segmentation, magnetic field measurements, minimum-bias events, missing transverse energy, muon spectrometer, muons, optical alignment systems, optical fibres, particle identification, photons, pile-up, pixel detectors, precision-tracking chambers, processor farm, proton-proton collisions, radiation-hard electronics, resistive-plate chambers, roman pots, sampling calorimeters, scintillator tiles, silicon micro-strip detectors, solenoidal field, superconducting magnets, taus, thin-gap chambers, time-over-threshold, toroidal field, tracking algorithms, transition radiation, trigger and data acquisition, trigger chambers, vertex measurement, vertexing algorithms, zero-degree calorimetry, 010308 nuclear & particles physics, Astronomía, Física experimental, Física, Experimental physics, Physical sciences, Experimental High Energy Physics, Physics::Accelerator Physics, High Energy Physics::Experiment
Abstract

The ATLAS detector as installed in its experimental cavern at point 1 at CERN is described in this paper. A brief overview of the expected performance of the detector when the Large Hadron Collider begins operation is also presented. Fil: Aad, G.. Aix-Marseille Université; Francia. Centre National de la Recherche Scientifique; Francia Fil: Anduaga, Xabier Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina Fil: Antonelli, S.. Università di Bologna; Italia Fil: Bendel, M.. Johannes Gutenberg Universitat Mainz; Alemania Fil: Breiler, B.. University of Montreal; Canadá Fil: Castrovillari, F.. Università della Calabria; Italia Fil: Civera, J.V.. Universidad de Valencia; España. Consejo Superior de Investigaciones Científicas; España Fil: Del Prete, T.. Università degli Studi di Pisa; Italia Fil: Dova, Maria Teresa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina Fil: Duffin, S.. Academy of Sciences of the Czech Republic; República Checa Fil: Fichet, S.. Université Paris Diderot - Paris 7; Francia. Universite Pierre et Marie Curie; Francia Fil: Gaumer, O.. Universidad de Ginebra; Suiza Fil: González Silva, María Laura. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Goodrick, M. J.. University of Cambridge; Reino Unido Fil: Goujdami, D.. Université Hassan II; Marruecos Fil: Herten, G.. Universität Freiburg; Alemania Fil: Jeremie, A. Université de Savoie; Francia. Centre National de la Recherche Scientifique; Francia Fil: Kieft, G.. University of New Mexico; Estados Unidos Fil: König, S.. Universität Freiburg; Alemania Fil: Kirk, J.. Rutherford Appleton Laboratory. Science and Technology Facilities Council; Reino Unido Fil: Lapin, V.V.. Federal Agency of Atomic Energy; Rusia Fil: LeGeyt, B.C.. University of Pennsylvania; Estados Unidos Fil: Love, J.. Boston University; Estados Unidos Fil: Merola,L.. Seconda Universita Degli Studi Di Napoli; Italia Fil: Miyagawa, P.S.. University of Manchester; Reino Unido Fil: Monticelli, Fernando Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina Fil: Piegaia, Ricardo Nestor. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina Fil: Plamondon, M.. Université Paris Sud; Francia. Centre National de la Recherche Scientifique; Francia Fil: Raith, B.. Universitat Bonn; Alemania Fil: Romeo, Gaston Leonardo. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Saavedra, A.F.. University of Sydney; Australia Fil: Sanchis Lozano, M.A. Universidad de Valencia; España. Consejo Superior de Investigaciones Científicas; España Fil: Schott, M.. Ludwig Maximilians Universitat; Alemania Fil: Soloviev, I.. Petersburg Nuclear Physics Institute; Rusia Fil: Tripiana, Martin Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina Fil: Zychacek, V.. Czech Technical University in Prague; República Checa

Published
2008
Full Text
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46. Comment: The FAIR Guiding Principles for scientific data management and stewardship

Author

Wilkinson, M D, Dumontier, M, Aalbersberg, I J, Appleton, G, Axton, M, Baak, A, Blomberg, N, Boiten, J W, Santos, L B D, Bourne, P E, Bouwman, J, Brookes, AJ, Clark, T, Crosas, M, Dillo, I, Dumon, O, Edmunds, S, Evelo, C T, Finkers, R, Gonzalez-Beltran, A, Gray, A J G, Groth, P, Goble, C, Grethe, J S, Heringa, J, 't Hoen, PAC, Hooft, R, Kuhn, T, Kok, R, Kok, J, Lusher, SJ, Martone, M E, Mons, A, Packer, A L, Persson, B, Rocca-Serra, P, Roos, M, van Schaik, R, Sansone, S A, Schultes, E, Sengstag, T, Slater, T, Strawn, G, Swertz, MA, Thompson, M, Lei, Johan, van Mulligen, Erik, Velterop, J, Waagmeester, A, Wittenburg, P, Wolstencroft, K, Zhao, J, Mons, B, Wilkinson, M D, Dumontier, M, Aalbersberg, I J, Appleton, G, Axton, M, Baak, A, Blomberg, N, Boiten, J W, Santos, L B D, Bourne, P E, Bouwman, J, Brookes, AJ, Clark, T, Crosas, M, Dillo, I, Dumon, O, Edmunds, S, Evelo, C T, Finkers, R, Gonzalez-Beltran, A, Gray, A J G, Groth, P, Goble, C, Grethe, J S, Heringa, J, 't Hoen, PAC, Hooft, R, Kuhn, T, Kok, R, Kok, J, Lusher, SJ, Martone, M E, Mons, A, Packer, A L, Persson, B, Rocca-Serra, P, Roos, M, van Schaik, R, Sansone, S A, Schultes, E, Sengstag, T, Slater, T, Strawn, G, Swertz, MA, Thompson, M, Lei, Johan, van Mulligen, Erik, Velterop, J, Waagmeester, A, Wittenburg, P, Wolstencroft, K, Zhao, J, and Mons, B

Published
2016

50. ISA software suite: supporting standards-compliant experimental\ud annotation and enabling curation at the community level\ud

Author

Rocca-Serra, P., Brandizi, M., Maguire, E., Sklyar, N., Taylor, C., Begley, K., Field, D., Harris, S., Hide, W., Hofmann, O., Neumann, S., Sterk, P., Tong, W., and Sansone, S-A.

Abstract

The first open source software suite for experimentalists and curators that (i) assists in the annotation and local management of experimental metadata from high-throughput studies employing one or a combination of omics and other technologies; (ii) empowers users to uptake community-defined checklists and ontologies; and (iii) facilitates submission to international public repositories.

Published
2010

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