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10 results on '"Santagada T"'

6. Fluoroquinolone derivatives: effects on neutrophil functional tests.

Author

Bersani C, Santagada T, Bertoletti R, Fietta A, and Gialdroni Grassi G

Subjects
Candida albicans, Chemotaxis, Leukocyte drug effects, Ciprofloxacin pharmacology, Humans, In Vitro Techniques, Neutrophils drug effects, Norfloxacin pharmacology, Ofloxacin pharmacology, Pefloxacin pharmacology, Phagocytosis drug effects, Staphylococcus aureus drug effects, Anti-Infective Agents pharmacology, Neutrophils physiology
Published
1987

8. In vitro activity of macrolides on human phagocytic functions.

Author

Fietta A, Bersani C, Santagada T, Bertoletti R, and Gialdroni Grassi G

Subjects
Blood Bactericidal Activity, Chemotaxis, Leukocyte drug effects, Erythromycin analogs & derivatives, Erythromycin pharmacology, Humans, Monocytes metabolism, Staphylococcus aureus drug effects, Staphylococcus aureus metabolism, Anti-Bacterial Agents pharmacology, Phagocytosis drug effects
Abstract

The aim of this study was to examine the in vitro activity of erythromycin, josamycin, flurithromycin, miocamycin and roxithromycin on some leukocyte functional parameters. All tested macrolides did not interfere with the frequency and index of phagocytosis, nitroblue tetrazolium reduction to formazan deposits and candidacidal activity of human polymorphonuclear leukocytes (p greater than 0.05). Among macrolide antibiotics, only flurithromycin significantly inhibited neutrophil chemotaxis at a high concentration (greater than or equal to 50 micrograms/ml). All macrolides, at 10 and 50 micrograms/ml, reduced the survival of a susceptible strain of Staphylococcus aureus ingested by human monocytes.

Published
1987

10. [Changes in monocyte chemotaxis in patients with primary lung neoplasia].

Author

Merlini C, Fietta A, Bersani C, Bertoletti R, Santagada T, and Gialdroni Grassi G

Subjects
Adenocarcinoma pathology, Carcinoma, Squamous Cell pathology, Complement System Proteins, Humans, Lipopolysaccharides, Male, Carcinoma, Bronchogenic pathology, Chemotaxis, Leukocyte drug effects, Leukocytes, Mononuclear pathology, Lung Neoplasms pathology
Published
1987

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