Search

Your search keyword '"Santamaría, Jesús"' showing total 536 results
Start Over Author "Santamaría, Jesús"
536 results on '"Santamaría, Jesús"'

1. Medicines Question Answering System, MeQA

Author

Santamaría, Jesús

Subjects
Computer Science - Computation and Language
Abstract

In this paper we present the first system in Spanish capable of answering questions about medicines for human use, called MeQA (Medicines Question Answering), a project created by the Spanish Agency for Medicines and Health Products (AEMPS, for its acronym in Spanish). Online services that offer medical help have proliferated considerably, mainly due to the current pandemic situation due to COVID-19. For example, websites such as Doctoralia, Savia, or SaludOnNet, offer Doctor Answers type consultations, in which patients or users can send questions to doctors and specialists, and receive an answer in less than 24 hours. Many of the questions received are related to medicines for human use, and most can be answered through the leaflets. Therefore, a system such as MeQA capable of answering these types of questions automatically could alleviate the burden on these websites, and it would be of great use to such patients.

Published
2021

13. Chemical and C and N stable isotope compositions of three species of epiphytic Tillandsia in a Caribbean coastal zone: air pollution sources and biomonitoring implications.

Author

Morera-Gómez, Yasser, Armas-Camejo, Alejandro, Santamaría, Jesús Miguel, Alonso-Hernández, Carlos Manuel, Lasheras, Esther, Widory, David, and Elustondo, David

Subjects
STABLE isotopes, COASTS, AIR pollution, ATMOSPHERIC nitrogen, BIOLOGICAL monitoring, CEMENT industries
Abstract

We characterized the elemental and C and N stable isotope compositions of Tillandsia fasciculata Sw., Tillandsia balbisiana Schult. & Schult.f. and Tillandsia recurvata (L.) L. samples collected in Cienfuegos (Cuba). Results showed high enrichment factors for S, Hg, Cd, Pb, P, Zn, Cu, Mo, Sb and Ca in all Tillandsia species, indicating inputs from local anthropogenic activities (road traffic, industries and cement production). Carbon concentrations and δ13C varied from 38.3–47.7 % and –20.4 to –13.4 ‰ within the three species, respectively. δ13C showed seasonal dependence with the dry and wet periods and more 13C-depleted values in urban/industrial areas, coherent with the input of anthropogenic emissions. Nitrogen concentrations (0.4–1.3 %) and δ15N values (–9.9–4.4 ‰) exhibit larger variations and are positively correlated in the three species. The most positive δ15N in T. recurvata (–0.2–4.4 ‰) are attributed to contributions from industrial activities and road traffic. In fact, both δ15N and total nitrogen (TN) values increase in sites with higher road traffic and show significant correlations with typical road traffic and industrial tracers. Finally, we calculate an average total nitrogen deposition rate of 4.4 ± 2.3 kg ha–1 a–1 from N content in T. recurvata, similar to the existing values determined in the region by field measurements, but higher than the global terrestrial average. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

19. A nanomedicine approach to targeting cuproplasia in cancer: Labile copper sequestration using polydopamine nanoparticles blocks tumor growth in vivo through altering metabolism and redox homeostasis.

Author

Bonet Aletá, Javier, primary, Encinas-Giménez, Miguel, additional, Oi, Miku, additional, Pezacki, Aidan T., additional, Sebastián, Victor, additional, de Martino, Alba, additional, Martín-Pardillos, Ana, additional, Martin-Duque, Pilar, additional, Hueso, José L., additional, Chang, Christopher J., additional, and Santamaría, Jesús, additional

Published
2023
Full Text
View/download PDF

23. Connective Tissue Diseases

Author

Santamaria, Jesus Rodriguez, Deonizio, Janyana M. D., Mukai, Maira Mitsue, Bonamigo, Renan Rangel, editor, and Dornelles, Sergio Ivan Torres, editor

Published
2018
Full Text
View/download PDF

27. Magnetically-triggered Nanocomposite Membranes: a Versatile Platform for Triggered Drug Release

Author

Hoare, Todd, Timko, Brian P., Santamaria, Jesus, Goya, Gerardo F., Irusta, Silvia, Lin, Debora, Lau, Samantha, Langer, Robert, and Kohane, Daniel S.

Subjects
Condensed Matter - Materials Science, Physics - Biological Physics, Quantitative Biology - Subcellular Processes
Abstract

Drug delivery devices based on nanocomposite membranes containing thermoresponsive nanogels and superparamagnetic nanoparticles have been demonstrated to provide reversible, on-off drug release upon application (and removal) of an oscillating magnetic field. The dose of drug delivered can be tuned by engineering the phase transition temperature of the nanogel, the loading of nanogels in the membrane, and the membrane thickness, allowing for the delivery of drugs over several orders of magnitude of release rates. The zero-order kinetics of drug release through the membranes permit drug doses from a specific device to be tuned according to the duration of the magnetic field. Drugs over a broad range of molecular weights (500-40,000 Da) can be delivered by the same membrane device. Membrane-to-membrane and cycle-to-cycle reproducibility is demonstrated, suggesting the general utility of these membranes for drug delivery., Comment: 13 Pages + Supplementary material

Published
2011
Full Text
View/download PDF

28. A Magnetically-Triggered Composite Membrane for On-Demand Drug Delivery

Author

Hoare, Todd, Santamaria, Jesus, Goya, Gerardo F., Irusta, Silvia, Lin, Debora, Lau, Samantha, Padera, Robert, Langer, Robert, and Kohane, Daniel S.

Subjects
Condensed Matter - Materials Science
Abstract

Nanocomposite membranes based on thermosensitive, poly(N-isopropylacrylamide)-based nanogels and magnetite nanoparticles have been designed to achieve "on-demand" drug delivery upon the application of an oscillating magnetic field. On-off release of sodium fluorescein over multiple magnetic cycles has been successfully demonstrated using prototype membrane-based devices. The total drug dose delivered was directly proportional to the duration of the "on" pulse. The membranes were non-cytotoxic, biocompatible, and retained their switchable flux properties after 45 days of subcutaneous implantation., Comment: 12 pages, 4 figures

Published
2011

36. Modelling and mapping heavy metal and nitrogen concentrations in moss in 2010 throughout Europe by applying Random Forests models

Author

Nickel, Stefan, Schröder, Winfried, Wosniok, Werner, Harmens, Harry, Frontasyeva, Marina V., Alber, Renate, Aleksiayenak, Julia, Barandovski, Lambe, Blum, Oleg, Danielsson, Helena, de Temmermann, Ludwig, Dunaev, Anatoly M., Fagerli, Hilde, Godzik, Barbara, Ilyin, Ilia, Jonkers, Sander, Jeran, Zvonka, Pihl Karlsson, Gunilla, Lazo, Pranvera, Leblond, Sebastien, Liiv, Siiri, Magnússon, Sigurður H., Mankovska, Blanka, Martínez-Abaigar, Javier, Piispanen, Juha, Poikolainen, Jarmo, Popescu, Ion V., Qarri, Flora, Radnovic, Dragan, Santamaria, Jesus Miguel, Schaap, Martijn, Skudnik, Mitja, Špirić, Zdravko, Stafilov, Trajce, Steinnes, Eiliv, Stihi, Claudia, Suchara, Ivan, Thöni, Lotti, Uggerud, Hilde Thelle, and Zechmeister, Harald G.

Published
2017
Full Text
View/download PDF

41. Superfluorinated Extracellular Vesicles for In Vivo Imaging by 19F-MRI

Author

Sancho-Albero, María, primary, Ayaz, Nazeeha, additional, Sebastian, Victor, additional, Chirizzi, Cristina, additional, Encinas-Gimenez, Miguel, additional, Neri, Giulia, additional, Chaabane, Linda, additional, Luján, Lluís, additional, Martin-Duque, Pilar, additional, Metrangolo, Pierangelo, additional, Santamaría, Jesús, additional, and Baldelli Bombelli, Francesca, additional

Published
2023
Full Text
View/download PDF

42. Pivotal role of the protein corona in the cell uptake of fluorinated nanoparticles with increased sensitivity for 19F-MR imaging

Author

Gatti, Lodovico, primary, Chirizzi, Cristina, additional, Rotta, Giulia, additional, Milesi, Pietro, additional, Sancho-Albero, María, additional, Sebastián, Victor, additional, Mondino, Anna, additional, Santamaría, Jesús, additional, Metrangolo, Pierangelo, additional, Chaabane, Linda, additional, and Bombelli, Francesca Baldelli, additional

Published
2023
Full Text
View/download PDF

45. Microwave-Driven Exfoliation of Bulk 2H-MoS2 after Acetonitrile Prewetting Produces Large-Area Ultrathin Flakes with Exceptionally High Yield

Author

Quirós-Ovies, Ramiro, Laborda, María, Sabanés, Natalia Martín, Martín-Pérez, Lucía, Silva, Sara Moreno-Da, Burzurí, Enrique, Sebastian, Víctor, Pérez, Emilio M., and Santamaría, Jesús

Subjects
General Engineering, General Physics and Astronomy, General Materials Science
Abstract

2D materials display exciting properties in numerous fields, but the development of applications is hindered by the low yields, high processing times, and impaired quality of current exfoliation methods. In this work we have used the excellent MW absorption properties of MoS2 to induce a fast heating that produces the near-instantaneous evaporation of an adsorbed, low boiling point solvent. The sudden evaporation creates an internal pressure that separates the MoS2 layers with high efficiency, and these are kept separated by the action of the dispersion solvent. Our fast method (90 s) gives high yields (47% at 0.2 mg/mL, 35% at 1 mg/mL) of highly exfoliated material (90% under 4 layers), large area (up to several μm2), and excellent quality (no significant MoO3 detected).

Published
2023

Catalog

Books, media, physical & digital resources
See catalog results