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4. Active elderly and health—can moderate exercise improve health and wellbeing in older adults? Protocol for a randomized controlled trial

Author

Carta, Mauro Giovanni, Cossu, Giulia, Pintus, Elisa, Zoccheddu, Rosanna, Callia, Omar, Conti, Giuliana, Pintus, Mirra, Gonzalez, Cesar Ivan Aviles, Massidda, Maria Valeria, Mura, Gioia, Sardu, Claudia, Contu, Paolo, Minerba, Luigi, Demontis, Roberto, Pau, Massimiliano, Finco, Gabriele, Cocco, Eleonora, Penna, Maria Petronilla, Orrù, Germano, Kalcev, Goce, Cabras, Federico, Lorrai, Stefano, Loviselli, Andrea, Velluzzi, Fernanda, Monticone, Marco, Cacace, Enrico, Musu, Mario, Rongioletti, Franco, Cauli, Alberto, Ruggiero, Valeria, Scano, Alessandra, Crisafulli, Antonio, Cosentino, Sofia, Atzori, Laura, Massa, Elena, Mela, Quirico, Fortin, Dario, Migliaccio, Gianmario, Nardi, Antonio Egidio, Angermeyer, Matthias, and Preti, Antonio

Published
2021
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9. What do young people know about HIV? Results of a cross sectional study on 18-24-year-old students

Author

MEREU, ALESSANDRA, LIORI, ARIANNA, FADDA, LUCA, PUDDU, MASSIMILIANO, CHESSA, LUCHINO, CONTU, PAOLO, and SARDU, CLAUDIA

Subjects
Health Promotion and Education, Students, HIV knowledge, HIV perception, HIV prevention, Health Promotion
Abstract

Increasing people’s knowledge of transmission, prevention, early diagnosis, and available treatments is a key step toward HIV control; it means setting the conditions for empowerment and enabling individuals to make aware choices about the prevention strategy best suited to their needs. This study aims to identify unmet needs on HIV knowledge among freshman students. A cross sectional study was carried out at the University of Cagliari, which is an Italian public state university. Data were collected by means of an anonymous questionnaire; the final sample included 801 students. Results offer a detailed picture of students’ knowledge and perceptions of HIV. Several topics deserve to be better understood by students, but the main gaps relate to the pre-exposure prophylaxis and the decreased likelihood of sexually transmitting HIV due to early treatments. Students’ vision of the quality of life of people living with HIV was negatively affected by perceiving as relevant the effects of HIV on physical health or on sexual/affective domains, while conversely, it seemed positively affected by knowing that current treatments are useful for counteracting physical symptoms and decreasing the possibility of transmitting HIV. Being aware of the potential benefits of current therapies could favour a less negative view, in line with the current state of the beneficial effects of HIV treatment. Universities are a valuable setting to bridge the HIV knowledge gap and thus also contribute to tackling stigma and actively promoting HIV testing., Journal of Preventive Medicine and Hygiene, Vol. 63 No. 4 (2022): 2022634

Published
2023
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11. VCA in the Era of the COVID-19 Pandemic

Author

Petruzzo, Palmina, Kanitakis, Jean, Sardu, Claudia, Bassiri Gharb, Bahar, Morelon, Emmanuel, Amer, Hatem, Barret, Juan, Burt, James, Brandacher, Gerald, Gomez, Tomas, Kay, Simon, Kaminska, Dorotha, Kaufman, Christina L, Kumar, Dinesh S, Iglesias, Martin, Iyer, Subramania, Landin, Luis, Lanzetta, Marco, Lassus, Patrick, Levin, Scott, Papay, Francis, Pomahac, Bohdan, Sassu, Paolo, Satbhai, Nilesh G, Talbot, Simon, VCA-COVID Survey Group, HUS Musculoskeletal and Plastic Surgery, Clinicum, and Plastiikkakirurgian yksikkö

Subjects
Herpesvirus 4, Human, Transplantation, ORGAN-TRANSPLANTATION, REGISTRY, COVID-19, Humans, 3126 Surgery, anesthesiology, intensive care, radiology, Antigens, Viral, Pandemics
Abstract

Since its onset in the beginning of 2020, the coronavirus disease 2019 (COVID-19) pandemic has impacted the transplantation community broadly. Indeed, the number of transplantations decreased dramatically and transplantations were temporarily shut down in many localities.1,2 The dramatic impact of the COVID-19 pandemic on solid organ transplant (SOT) recipients began to emerge with reports initially from China, Spain, and Italy. The prevalence of COVID-19 in SOT during the first pandemic wave varied geographically, but despite several reports, the effective incidence of the COVID-19 in SOT recipients remains unclear.2-5 Most relevant, solid organ transplantation (heart, liver, and kidney) rates declined, exposing candidates to an increased rate of waitlist mortality.Vascularized composite allotransplantation (VCA) is an emerging field of transplantation; approximately 200 to 300 procedures have been performed thus far6,7 since the first hand transplantation in 1998. VCA (including upper and lower extremity, face, larynx, uterus, penis and abdominal wall transplants) is usually contemplated as life-enhancing rather than life-saving procedures but nevertheless requires lifelong immunosuppression. Although, VCA recipients are exposed to the same risks as SOT recipients, no relevant data have been so far published on the impact of COVID-19 on VCA.

Published
2022

14. Moderate Exercise Improves Cognitive Function in Healthy Elderly People: Results of a Randomized Controlled Trial

Author

Carta, Mauro Giovanni, primary, Cossu, Giulia, additional, Pintus, Elisa, additional, Zaccheddu, Rosanna, additional, Callia, Omar, additional, Conti, Giuliana, additional, Pintus, Mirra, additional, Aviles Gonzalez, Cesar Ivan, additional, Massidda, Maria Valeria, additional, Mura, Gioia, additional, Sardu, Claudia, additional, Contu, Paolo, additional, Minerba, Luigi, additional, Demontis, Roberto, additional, Pau, Massimiliano, additional, Finco, Gabriele, additional, Cocco, Eleonora, additional, Penna, Maria Pietronilla, additional, Orr, Germano, additional, Kalcev, Goce, additional, Cabras, Federico, additional, Lorrai, Stefano, additional, Loviselli, Andrea, additional, Velluzzi, Fernanda, additional, Monticone, Marco, additional, Cacace, Enrico, additional, Musu, Mario, additional, Rongioletti, Franco, additional, Cauli, Alberto, additional, Ruggiero, Valeria, additional, Scano, Alessandra, additional, Crisafulli, Antonio, additional, Cosentino, Sofia, additional, Atzori, Laura, additional, Massa, Elena, additional, Mela, Quirico, additional, Fortin, Dario, additional, Migliaccio, Gianmario, additional, Machado, Sergio, additional, Romano, Ferdinando, additional, and Preti, Antonio, additional

Published
2021
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17. Additional file 1 of Active elderly and health—can moderate exercise improve health and wellbeing in older adults? Protocol for a randomized controlled trial

Author

Carta, Mauro Giovanni, Cossu, Giulia, Pintus, Elisa, Zoccheddu, Rosanna, Callia, Omar, Conti, Giuliana, Mirra Pintus, Gonzalez, Cesar Ivan Aviles, Massidda, Maria Valeria, Mura, Gioia, Sardu, Claudia, Contu, Paolo, Minerba, Luigi, Demontis, Roberto, Pau, Massimiliano, Finco, Gabriele, Cocco, Eleonora, Penna, Maria Petronilla, Orrù, Germano, Kalcev, Goce, Cabras, Federico, Lorrai, Stefano, Loviselli, Andrea, Velluzzi, Fernanda, Monticone, Marco, Cacace, Enrico, Musu, Mario, Rongioletti, Franco, Cauli, Alberto, Ruggiero, Valeria, Scano, Alessandra, Crisafulli, Antonio, Cosentino, Sofia, Atzori, Laura, Massa, Elena, Mela, Quirico, Fortin, Dario, Migliaccio, Gianmario, Nardi, Antonio Egidio, Angermeyer, Matthias, and Preti, Antonio

Abstract

Additional file 1. See the SPIRIT 2013 checklist.

Published
2021
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18. Alcohol Consumption Is a Modifiable Risk Factor for Breast Cancer: Are Women Aware of This Relationship?

Author

Agabio, Roberta, Madeddu, Clelia, Contu, Paolo, Cosentino, Sofia, Deiana, Monica, Massa, Elena, Mereu, Alessandra, Politi, Carola, Sardu, Claudia, and Sinclair, Julia M A

Subjects
BREAST tumor risk factors, HEALTH literacy, ALCOHOL drinking, QUESTIONNAIRES, DESCRIPTIVE statistics, WOMEN'S health, HEALTH promotion
Abstract

Aims Despite alcohol consumption being a dose-dependent risk factor for breast cancer, a recent study conducted in the UK found <20% of women attending breast screening programmes were aware of this relationship and proposed proper information campaigns need to be conducted. We aimed to investigate the awareness of this relationship among a related sample of Italian women to evaluate whether similar information campaigns should also be conducted in Italy. Methods The questionnaire used by the UK study was translated into Italian, slightly modified for the Italian context, validated and submitted to a sample of Italian women. Results Overall 507 women were interviewed. Among them, 160 were classified as breast cancer screening attenders (SG), 44 as symptomatic breast clinic attenders (CAG) and 303 as non-screening group (NSG). Alcohol was correctly identified as a risk factor for breast cancer by 16.9, 11.4 and 14.9% of participants of SG, CAG and NSG, respectively without differences between the three groups. Despite the methodological differences, the rates of participants who correctly identified alcohol as a risk factor among women attending breast screening programmes were surprisingly similar between the study conducted in UK (15.7%) and the present study (16.9%). Conclusion The results of the present study confirm the limited awareness of the relationship between alcohol consumption and risk of developing breast cancer among women and suggest the urgent need to conduct proper awareness-raising campaigns to counter this in the Italian female population. [ABSTRACT FROM AUTHOR]

Published
2022
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20. Comparison of Multimaterial Decomposition Fat Fraction with DECT and Proton Density Fat Fraction with IDEAL IQ MRI for Quantification of Liver Steatosis in a Population Exposed to Chemotherapy

Author

Corrias, Giuseppe, primary, Erta, Marco, additional, Sini, Marcello, additional, Sardu, Claudia, additional, Saba, Luca, additional, Mahmood, Usman, additional, Huicochea Castellanos, Sandra, additional, Bates, David, additional, Mondanelli, Nicola, additional, Thomsen, Brian, additional, Carollo, Gabriella, additional, Sawan, Peter, additional, and Mannelli, Lorenzo, additional

Published
2021
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28. Graft vasculopathy in upper extremity allotransplantation: Results of a retrospective high‐resolution ultrasonographic study.

Author

Petruzzo, Palmina, Luong, Stephane, Kanitakis, Jean, Sardu, Claudia, Feugier, Patrick, Danjou, Fabrice, Gazarian, Aram, Badet, Lionel, and Morelon, Emmanuel

Subjects
FORELIMB, RADIAL artery, ARTERIES
Abstract

Graft vasculopathy (GV) is the most severe pathologic change of chronic rejection in vascularized composite allotransplantation. Since 2012, the intimal media thickness (IMT) of radial and ulnar arteries was annually monitored by high‐resolution ultrasonography in seven bilateral upper extremity transplant (UET) patients. We also investigated the IMT of seven matched healthy subjects (controls). No significant difference between IMT values of controls and UET patients was found. The median IMT values of recipient radial and ulnar arteries were 0.23 mm and 0.25 mm, respectively, while the median IMT values of grafted radial and ulnar arteries were 0.27 mm and 0.30 mm, respectively. There was a statistically significant difference in the IMT values of the grafted and recipient ulnar arteries (p =.043), but this difference was no longer significant when patient #2 was excluded. He showed a significant difference between recipient and grafted arteries and significantly higher IMT values (p =.001) of his grafted arteries compared with those of all transplanted patients. This patient developed GV leading to graft loss 11 years after the transplantation. In conclusion, this study showed a significant IMT increase in an UET recipient who developed GV. [ABSTRACT FROM AUTHOR]

Published
2021
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29. The link between thyroid autoimmunity (antithyroid peroxidase autoantibodies) with anxiety and mood disorders in the community: a field of interest for public health in the future

Author

Sardu Claudia, Cadeddu Mariangela, Massa Sergio, Hardoy Maria, Loviselli Andrea, Carta Mauro, Carpiniello Bernardo, Dell'Osso Liliana, and Mariotti Stefano

Subjects
Psychiatry, RC435-571
Abstract

Abstract Background To evaluate the association between mood and anxiety disorders and thyroid autoimmunity in a community sample. Methods: A community based sample of 222 subjects was examined. Psychiatric diagnoses were formulated using the International Composite Diagnostic Interview Simplified (CIDIS), according to DSM-IV criteria. All subjects underwent a complete thyroid evaluation including physical examination, thyroid echography and measure of serum free T4 (FT4), free T3 (FT3), thyroid-stimulating hormone (TSH) and anti-thyroid peroxidase autoantibodies (anti-TPO). Results 16.6% of the overall sample had an anti-TPO value above the normal cut-off. Subjects with at least one diagnosis of anxiety disorders (OR = 4.2, C.L. 95% 1.9–38.8) or mood disorders (OR = 2.9, Cl 95% 1.4–6.6, P < 0.011) were positive for serum anti-TPO more frequently than subjects without mood or anxiety disorders. A statistically significant association with anti-TPO+ was found in Anxiety Disorder Not Otherwise Specified (OR = 4.0, CL 95% 1.1–15.5), in Major Depressive Episode (OR = 2.7, CL 95% 1.1–6.7) and Depressive Disorder Not Otherwise Specified (OR = 4.4, S CL 95% 1–19.3). Conclusions The study seems to suggest that individuals in the community with thyroid autoimmunity may be at high risk for mood and anxiety disorders. The psychiatric disorders and the autoimmune reaction seem to be rooted in a same (and not easy correctable) aberrancy in the immuno-endocrine system. Should our results be confirmed, the findings may be of great interest for future preventive and case finding projects.

Published
2004
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30. Physician’s Global Assessment in Psoriatic Arthritis: A Multicenter GRAPPA Study

Author

Cauli, Alberto, primary, Gladman, Dafna D., additional, Mathieu, Alessandro, additional, Olivieri, Ignazio, additional, Porru, Giovanni, additional, Tak, Paul P., additional, Sardu, Claudia, additional, Scarpa, Raffaele, additional, Marchesoni, Antonio, additional, Taylor, William J., additional, Salvarani, Carlo, additional, Kalden, Joachim, additional, Lubrano, Ennio, additional, Carneiro, Sueli, additional, Piga, Matteo, additional, Floris, Alberto, additional, Desiati, Francesca, additional, Flynn, John A., additional, D’Angelo, Salvatore, additional, van Kuijk, Arno W.R., additional, Catanoso, Maria Grazia, additional, Caso, Francesco, additional, Contu, Paolo, additional, Ujfalussy, Ilona, additional, Helliwell, Philip S., additional, and Mease, Philip J., additional

Published
2018
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31. Intrathecal oligoclonal bands synthesis in multiple sclerosis: is it always a prognostic factor?

Author

Frau, Jessica, primary, Villar, Luisa Maria, additional, Sardu, Claudia, additional, Secci, Maria Antonietta, additional, Schirru, Lucia, additional, Ferraro, Diana, additional, Coghe, Giancarlo, additional, Lorefice, Lorena, additional, Fenu, Giuseppe, additional, Bedin, Roberta, additional, Sola, Patrizia, additional, Marrosu, Maria Giovanna, additional, and Cocco, Eleonora, additional

Published
2017
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32. Multiple sclerosis and HLA genotypes: A possible influence on brain atrophy

Author

Lorefice, Lorena, primary, Fenu, Giuseppe, additional, Sardu, Claudia, additional, Frau, Jessica, additional, Coghe, Giancarlo, additional, Costa, Gianna, additional, Schirru, Lucia, additional, Secci, Maria Antonietta, additional, Sechi, Vincenzo, additional, Barracciu, Maria Antonietta, additional, Marrosu, Maria Giovanna, additional, and Cocco, Eleonora, additional

Published
2017
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33. Multiple sclerosis and HLA genotypes: A possible influence on brain atrophy.

Author

Lorefice, Lorena, Fenu, Giuseppe, Sardu, Claudia, Frau, Jessica, Coghe, Giancarlo, Costa, Gianna, Schirru, Lucia, Secci, Maria Antonietta, Sechi, Vincenzo, Barracciu, Maria Antonietta, Marrosu, Maria Giovanna, and Cocco, Eleonora

Subjects
MULTIPLE sclerosis, CEREBRAL atrophy, HAPLOTYPES, GENETIC polymorphisms, ALLELES
Abstract

Background: The strongest genetic determinant for multiple sclerosis (MS) is located at the human leukocyte antigen (HLA) class II DRB1 and DQB1 loci. Objectives: To investigate the possible role of predisposing HLA genotypes in determining brain atrophy. Methods: HLA genotypes were categorized as high risk (two predisposing haplotypes) or medium/low risk (one or no predisposing haplotypes). Patients underwent a brain magnetic resonance imaging (MRI) study and volumes of white matter (WM), gray matter (GM), and whole brain (WB) were estimated with SIENAX. Longitudinal atrophy was also assessed with SIENA. Results: The study included 240 MS patients. In 51/240 (21%) subjects, a high-risk HLA genotype was observed, while medium- and low-risk HLA genotypes were 109/240 (45%) and 80/240 (34%), respectively. Multiple regression analysis found that the high-risk HLA genotype was associated with significant reduction in WB (p = 0.02) and GM (p = 0.03) volumes compared with the medium-/low-risk HLA genotypes, independently from MS clinical features. The longitudinal study included 60 patients and showed a brain volume loss of −0.79% in high-risk HLA genotype group versus −0.56% in low-risk HLA genotype. Conclusion: Our results suggest an influence of HLA genotype on WB and GM atrophy. Further investigations are necessary to confirm these findings. [ABSTRACT FROM AUTHOR]

Published
2019
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36. Citizens’ involvement in risk management: the view of community members

Author

Sardu, Claudia, Mereu, Alessandra, Sotgiu, Alessandra, Porceddu, Roberta, Porcedda, Emanuela, Contu, Antonio, and Contu, Paolo

Subjects
Risk management, socioeconomic context, lcsh:Public aspects of medicine, lcsh:R, DOAJ:Public Health, lcsh:Medicine, trust, lcsh:RA1-1270, DOAJ:Health Sciences, health care economics and organizations
Abstract

Background: Industrial risk management plays a central role in creating supportive environments for health. This paper examines the community’s trust in citizens’ involvement in risk management, investigating differencesamong settings exposed to different levels of industrial risk. Additionally it aims to identify the social demographic characteristics of those manifesting high trust in citizens’ involvement in risk management.Methods: The survey, performed in Sardinia between 2006 and 2007, was carried out in three representative areas this Region: a metropolitan area, an industrial area, and a rural area. A questionnaire was administered to 1,104 citizens to investigate community’s trust in citizens as “risk managers”. Results: Trust in citizens’ involvement in risk management was expressed to a greater extent by residents in the rural area, by those with a high level of education, and by older women. The expression of high trust in citizens’ involvement was more likely in older higher-educated women (58-69%) than in lower educated ones (52-63%) and, to a lesserextent, in both genders with higher education (42-51%).Conclusions: A consistent number of the community’s members would entrust citizens with risk management not only in areas with a severe industrial impact, but also in those areas where industrial risk is considered of limited entity. The community’s tendency towards citizens’ involvement in risk management appears to be an intrinsic trait of the community itself rather than an attitude triggered by a specific problem. Older women, and adults with higher education can be recognised as categories in which potential early adopters of risk management can be easily found.

Published
2010

37. Role of interferon-beta in Mycobacterium avium subspecies paratuberculosis antibody response in Sardinian MS patients

Author

Frau, Jessica, primary, Cossu, Davide, additional, Coghe, Giancarlo, additional, Lorefice, Lorena, additional, Fenu, Giuseppe, additional, Porcu, Gianluca, additional, Sardu, Claudia, additional, Murru, Maria Rita, additional, Tranquilli, Stefania, additional, Marrosu, Maria Giovanna, additional, Sechi, Leonardo Antonio, additional, and Cocco, Eleonora, additional

Published
2015
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39. Constructional apraxia in frontotemporal dementia associated with the C9orf72 mutation: Broadening the clinical and neuropsychological phenotype

Author

Floris, Gianluca, primary, Borghero, Giuseppe, additional, Cannas, Antonino, additional, Di Stefano, Francesca, additional, Ruiu, Elisa, additional, Murru, Maria R., additional, Corongiu, Daniela, additional, Cuccu, Stefania, additional, Tranquilli, Stefania, additional, Sardu, Claudia, additional, Marrosu, Maria G., additional, Chiò, Adriano, additional, and Marrosu, Francesco, additional

Published
2014
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41. Influence of treatments in multiple sclerosis disability: A cohort study

Author

Cocco, Eleonora, primary, Sardu, Claudia, additional, Spinicci, Gabriella, additional, Musu, Luigina, additional, Massa, Rita, additional, Frau, Jessica, additional, Lorefice, Lorena, additional, Fenu, Giuseppe, additional, Coghe, Giancarlo, additional, Massole, Serenella, additional, Maioli, Maria Antonietta, additional, Piras, Rachele, additional, Melis, Marta, additional, Porcu, Gianluca, additional, Mamusa, Elena, additional, Carboni, Nicola, additional, Contu, Paolo, additional, and Marrosu, Maria Giovanna, additional

Published
2014
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44. Interaction between HLA-DRB1-DQB1 Haplotypes in Sardinian Multiple Sclerosis Population

Author

Cocco, Eleonora, primary, Murru, Raffaele, additional, Costa, Gianna, additional, Kumar, Amit, additional, Pieroni, Enrico, additional, Melis, Cristina, additional, Barberini, Luigi, additional, Sardu, Claudia, additional, Lorefice, Lorena, additional, Fenu, Giuseppe, additional, Frau, Jessica, additional, Coghe, Giancarlo, additional, Carboni, Nicola, additional, and Marrosu, Maria Giovanna, additional

Published
2013
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46. HLA-DRB1-DQB1 Haplotypes Confer Susceptibility and Resistance to Multiple Sclerosis in Sardinia

Author

Cocco, Eleonora, primary, Sardu, Claudia, additional, Pieroni, Enrico, additional, Valentini, Maria, additional, Murru, Raffaele, additional, Costa, Gianna, additional, Tranquilli, Stefania, additional, Frau, Jessica, additional, Coghe, Giancarlo, additional, Carboni, Nicola, additional, Floris, Matteo, additional, Contu, Paolo, additional, and Marrosu, Maria Giovanna, additional

Published
2012
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