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16 results on '"Saruta, Yusuke"'

3. Development of labor-saving system for the maintenance of the telescopes under the extreme environment using a remote-controlled robot

Author

Narasaki, Shota, primary, Kawaguchi, Noboru, additional, Hirano, Masaki, additional, Nakaoji, Toshitaka, additional, Ezaki, Yutaka, additional, Saruta, Yusuke, additional, Hoshino, Hayato, additional, Haruna, Masaki, additional, Michida, Rui, additional, Tomida, Yosuke, additional, Koda, Yoshitaka, additional, and Sato, Toru, additional

Published
2020
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5. Design and status overview of TMT telescope structure

Author

Marshall, Heather K., Spyromilio, Jason, Usuda, Tomonori, Sugimoto, Masahiro, Ezaki, Yutaka, Kinoshita, Kyle, Sadjadpour, Amir, Takaki, Junji, Saruta, Yusuke, Hattori, Tomoya, Hoshino, Hayato, Hosokawa, Yoshihiro, Endo, Makoto, Sugie, Yusuke, Haruna, Masaki, Kawaguchi, Noboru, Horiuchi, Yasushi, Tabata, Masaki, Terada, Hiroshi, Tazawa, Seiichi, Okita, Hirofumi, Omata, Koji, Kusumoto, Hiroshi, Okamoto, Koichi, Saito, Masao, and Usuda, Tomonori

Published
2024
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6. Dupilumab treatment ameliorates clinical and hematological symptoms, including blood eosinophilia, in patients with atopic dermatitis.

Author

Yamauchi, Teruo, Sasaki, Shun, Lee, Eun Seon, Tamura, Takayuki, Seki, Marina, Miwa, Tasuku, Kobayashi, Kae, Saruta, Yusuke, Kitami, Yuki, Sueki, Hirohiko, and Watanabe, Hideaki

Subjects
ATOPIC dermatitis, IMMUNOGLOBULIN E, EOSINOPHILIA, BODY surface area, BLOOD lactate
Abstract

Background: Atopic dermatitis (AD) is an allergic disease that affects individuals of various ages. Recently, the IL‐4/13 inhibitor dupilumab has gained regulatory approval for clinical use in AD patients. Dupilumab has been reported to reduce several markers of AD, including the serum levels of thymus and activation‐regulated chemokine (TARC/CCL17), blood lactate dehydrogenase (LDH), and serum total immunoglobulin E (IgE). Methods: We retrospectively reviewed data from 40 AD patients who were treated with dupilumab. Eczema Area and Severity Index (EASI), Investigator's Global Assessment (IGA), body surface area (BSA) scores, TARC, LDH, total IgE, and eosinophil count in peripheral blood were assessed for a total of 32 weeks. Results: The EASI, IGA, and BSA scores improved significantly with treatment, indicating a reduction in AD severity. Serum TARC and LDH levels also significantly decreased with treatment. Serum IgE levels were unchanged at 2 weeks of treatment but decreased significantly between 4 and 32 weeks. The number of eosinophils in the peripheral blood decreased at 4, 16, and 32 weeks after treatment initiation. Conclusions: Several studies have reported that serum TARC, LDH, and total IgE levels are reduced by dupilumab treatment. Our real‐world data are the first to demonstrate a reduction in blood eosinophilia in patients who receive clinical treatment with dupilumab. [ABSTRACT FROM AUTHOR]

Published
2021
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10. Overview of key technologies for TMT telescope structure

Author

Ezaki, Yutaka, additional, Kato, Atsushi, additional, Hattori, Tomoya, additional, Saruta, Yusuke, additional, Sofuku, Satoru, additional, Nakaoji, Toshitaka, additional, Kawaguchi, Noboru, additional, Takaki, Junji, additional, Horiuchi, Yasushi, additional, Haruna, Masaki, additional, Tabata, Masaki, additional, Hosokawa, Yoshihiro, additional, Kusumoto, Hiroshi, additional, and Usuda, Tomonori, additional

Published
2016
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11. Segment handling system prototype progress for Thirty Meter Telescope

Author

Sofuku, Satoru, additional, Ezaki, Yutaka, additional, Kawaguchi, Noboru, additional, Nakaoji, Toshitaka, additional, Takaki, Junji, additional, Horiuchi, Yasushi, additional, Saruta, Yusuke, additional, Haruna, Masaki, additional, Kim, Ieyoung, additional, Fukushima, Kazuhiko, additional, Domae, Yukiyasu, additional, Hatta, Toshiyuki, additional, Yoshitake, Shinya, additional, and Hoshino, Hayato, additional

Published
2016
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12. Preliminary Design Study of the TMT Telescope Structure System: Overview

Author

Stepp, Larry M., Gilmozzi, Roberto, Hall, Helen J., Usuda, Tomonori, Ezaki, Yutaka, Kawaguchi, Noburu, Nagae, Kazuhiro, Kato, Atsushi, Takaki, Junji, Hirano, Masaki, Hattori, Tomoya, Tabata, Masaki, Horiuchi, Yasushi, Saruta, Yusuke, Sofuku, Satoru, Itoh, Noboru, Oshima, Takeharu, Takanezawa, Takashi, Endo, Makoto, Inatani, Junji, Iye, Masanori, Sadjadpour, Amir, Sirota, Mark, Roberts, Scott, Stepp, Larry, Stepp, Larry M., Gilmozzi, Roberto, Hall, Helen J., Usuda, Tomonori, Ezaki, Yutaka, Kawaguchi, Noburu, Nagae, Kazuhiro, Kato, Atsushi, Takaki, Junji, Hirano, Masaki, Hattori, Tomoya, Tabata, Masaki, Horiuchi, Yasushi, Saruta, Yusuke, Sofuku, Satoru, Itoh, Noboru, Oshima, Takeharu, Takanezawa, Takashi, Endo, Makoto, Inatani, Junji, Iye, Masanori, Sadjadpour, Amir, Sirota, Mark, Roberts, Scott, and Stepp, Larry

Abstract

We present an overview of the preliminary design of the Telescope Structure System (STR) of Thirty Meter Telescope (TMT). NAOJ was given responsibility for the TMT STR in early 2012 and engaged Mitsubishi Electric Corporation (MELCO) to take over the preliminary design work. MELCO performed a comprehensive preliminary design study in 2012 and 2013 and the design successfully passed its Preliminary Design Review (PDR) in November 2013 and April 2014. Design optimizations were pursued to better meet the design requirements and improvements were made in the designs of many of the telescope subsystems as follows: 1. 6-legged Top End configuration to support secondary mirror (M2) in order to reduce deformation of the Top End and to keep the same 4% blockage of the full aperture as the previous STR design. 2. “Double Lower Tube” of the elevation (EL) structure to reduce the required stroke of the primary mirror (M1) actuators to compensate the primary mirror cell (M1 Cell) deformation caused during the EL angle change in accordance with the requirements. 3. M1 Segment Handling System (SHS) to be able to make removing and installing 10 Mirror Segment Assemblies per day safely and with ease over M1 area where access of personnel is extremely difficult. This requires semi-automatic sequence operation and a robotic Segment Lifting Fixture (SLF) designed based on the Compliance Control System, developed for controlling industrial robots, with a mechanism to enable precise control within the six degrees of freedom of position control. 4. CO2 snow cleaning system to clean M1 every few weeks that is similar to the mechanical system that has been used at Subaru Telescope. 5. Seismic isolation and restraint systems with respect to safety; the maximum acceleration allowed for M1, M2, tertiary mirror (M3), LGSF, and science instruments in 1,000 year return period earthquakes are defined in the requirements. The Seismic requirements apply to any EL angle, regardless of the operational

Published
2014

13. Preliminary design study of the TMT Telescope structure system: overview

Author

Usuda, Tomonori, additional, Ezaki, Yutaka, additional, Kawaguchi, Noboru, additional, Nagae, Kazuhiro, additional, Kato, Atsushi, additional, Takaki, Junji, additional, Hirano, Masaki, additional, Hattori, Tomoya, additional, Tabata, Masaki, additional, Horiuchi, Yasushi, additional, Saruta, Yusuke, additional, Sofuku, Satoru, additional, Itoh, Noboru, additional, Oshima, Takeharu, additional, Takanezawa, Takashi, additional, Endo, Makoto, additional, Inatani, Junji, additional, Iye, Masanori, additional, Sadjadpour, Amir, additional, Sirota, Mark, additional, Roberts, Scott, additional, and Stepp, Larry, additional

Published
2014
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16. Overview of key technologies for TMT telescope structure

Author

Hall, Helen J., Gilmozzi, Roberto, Marshall, Heather K., Ezaki, Yutaka, Kato, Atsushi, Hattori, Tomoya, Saruta, Yusuke, Sofuku, Satoru, Nakaoji, Toshitaka, Kawaguchi, Noboru, Takaki, Junji, Horiuchi, Yasushi, Haruna, Masaki, Tabata, Masaki, Hosokawa, Yoshihiro, Kusumoto, Hiroshi, and Usuda, Tomonori

Published
2016
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