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192 results on '"Sasaki, Takaya"'

7. Perioperative renal function change and oncological outcomes of radical nephroureterectomy in patients with upper tract urothelial carcinoma: A multicenter retrospective study

Author

Muramoto, Katsuki, Urabe, Fumihiko, Koike, Yuhei, Yamamoto, Shutaro, Suzuki, Hirotaka, Miyajima, Keiichiro, Fukuokaya, Wataru, Iwatani, Kosuke, Imai, Yu, Igarashi, Taro, Mori, Keiichiro, Aikawa, Koichi, Kimura, Shoji, Tashiro, Kojiro, Yamada, Yuta, Sasaki, Takaya, Sato, Shun, Yuen, Steffi Kar Kei, Shimomura, Tatsuya, Furuta, Akira, Tsuzuki, Shunsuke, Miki, Jun, and Kimura, Takahiro

Published
2024
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22. Fractional excretion of total protein predicts renal prognosis in Japanese patients with primary membranous nephropathy.

Author

Kuno, Hideaki, Kanzaki, Go, Sasaki, Takaya, Okabayashi, Yusuke, Haruhara, Kotaro, Yokote, Shinya, Koike, Kentaro, Ueda, Hiroyuki, Tsuboi, Nobuo, and Yokoo, Takashi

Subjects
JAPANESE people, BLOOD proteins, EXCRETION, KIDNEY diseases, KIDNEY failure, IGA glomerulonephritis
Abstract

Background Primary membranous nephropathy (pMN) is one of the most common types of glomerulonephritis, with a third of patients progressing to renal insufficiency. Various prognostic factors have been reported, of which urinary protein and renal function are the most critical parameters. Fractional excretion of total protein (FETP) indicates protein leakage that accounts for creatinine kinetics and serum protein levels. In this study, we investigated the association between FETP and renal prognosis in pMN. Methods We retrospectively identified 150 patients with pMN. FETP was calculated as follows: (serum creatinine × urine protein)/(serum protein × urine creatinine) %. We divided the patients into three groups according to FETP values and compared the clinicopathological findings. The primary outcome was an estimated glomerular filtration rate (eGFR) decrease of ≥30% from the baseline level. Results FETP was associated with urinary protein and renal function, Ehrenreich and Churg stage, and global glomerulosclerosis. The primary outcome was observed in 38 patients (25.3%), and the frequency of the primary outcome was higher in the high FETP group (P  = .001). FETP is higher than protein–creatinine ratio (PCR) in the area under the curve. In the multivariate analysis adjusted for age, eGFR, PCR and treatment, FETP was significantly associated with primary outcome (adjusted hazard ratio, 8.19; P  = .019). Conclusions FETP is a valuable indicator that can reflect the pathophysiology and is more useful than PCR as a predictor of renal prognosis in patients with Japanese pMN. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Does COVID-19 vaccination trigger gross hematuria in patients with IgA nephropathy?

Author

Okabe, Masahiro, Tsuboi, Nobuo, Hatanaka, Saeko, Haruhara, Kotaro, Yokote, Shinya, Shimizu, Akihiro, Sasaki, Takaya, Ueda, Hiroyuki, and Yokoo, Takashi

Subjects
COVID-19, COVID-19 pandemic, LITERATURE reviews, COVID-19 vaccines, IGA glomerulonephritis
Abstract

This article explores the potential link between COVID-19 vaccination and gross hematuria (blood in urine) in patients with immunoglobulin A nephropathy (IgAN). The study included 459 adult IgAN patients who received COVID-19 mRNA vaccinations, with 37% of them having a history of gross hematuria before vaccination. The results showed that there was no significant difference in the prevalence of gross hematuria after vaccination between patients with and without a history of gross hematuria. The study suggests that the factors governing the sensitivity to gross hematuria after vaccination and the natural history of IgAN may not be identical. However, the study has limitations, such as relying on patient reports and being conducted mostly on Japanese patients, so further research is needed to understand the immunological pathways involved in the development of gross hematuria due to infection or vaccination in IgAN patients. [Extracted from the article]

Published
2024
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28. Single-Nephron GFR in Different GBM Stages of Membranous Nephropathy

Author

Okabayashi, Yusuke, primary, Tsuboi, Nobuo, additional, Marumoto, Hirokazu, additional, Sasaki, Takaya, additional, Haruhara, Kotaro, additional, Kanzaki, Go, additional, Koike, Kentaro, additional, Ueda, Hiroyuki, additional, Shimizu, Akira, additional, Puelles, Victor G., additional, D’Agati, Vivette, additional, and Yokoo, Takashi, additional

Published
2023
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32. First Diagnosis of Immunoglobulin A Nephropathy Following SARS-CoV-2 mRNA Vaccination in Japan

Author

Yokote, Shinya, primary, Ueda, Hiroyuki, additional, Shimizu, Akihiro, additional, Okabe, Masahiro, additional, Haruhara, Kotaro, additional, Sasaki, Takaya, additional, Aoki, Ryousuke, additional, Joh, Kensuke, additional, Saeki, Harumi, additional, Tomita, Shigeki, additional, Tsuboi, Nobuo, additional, Suzuki, Hitoshi, additional, Suzuki, Yusuke, additional, and Yokoo, Takashi, additional

Published
2023
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43. Total Nephron Number and Single-Nephron Parameters in Patients with IgA Nephropathy

Author

Marumoto, Hirokazu, primary, Tsuboi, Nobuo, additional, D’Agati, Vivette D., additional, Sasaki, Takaya, additional, Okabayashi, Yusuke, additional, Haruhara, Kotaro, additional, Kanzaki, Go, additional, Koike, Kentaro, additional, Shimizu, Akira, additional, Kawamura, Tetsuya, additional, Rule, Andrew D., additional, Bertram, John F., additional, and Yokoo, Takashi, additional

Published
2021
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44. Podometrics in Japanese Living Donor Kidneys: Associations with Nephron Number, Age, and Hypertension

Author

Haruhara, Kotaro, primary, Sasaki, Takaya, additional, de Zoysa, Natasha, additional, Okabayashi, Yusuke, additional, Kanzaki, Go, additional, Yamamoto, Izumi, additional, Harper, Ian S., additional, Puelles, Victor G., additional, Shimizu, Akira, additional, Cullen-McEwen, Luise A., additional, Tsuboi, Nobuo, additional, Yokoo, Takashi, additional, and Bertram, John F., additional

Published
2021
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